Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_J20
(609 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1; ... 87 2e-16
UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole... 84 3e-15
UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein ... 81 2e-14
UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -... 81 2e-14
UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1... 81 3e-14
UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma j... 54 2e-06
UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cul... 54 4e-06
UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep: Cull... 49 1e-04
UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|R... 47 4e-04
UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.026
UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces pomb... 40 0.035
UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2... 38 0.14
UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin ... 38 0.25
UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involv... 37 0.43
UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1; ... 36 0.57
UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces cere... 36 0.75
UniRef50_A0KM85 Cluster: Putative membrane protein; n=2; Gammapr... 36 0.99
UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2; ... 36 0.99
UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protei... 34 3.0
UniRef50_Q9V2Q2 Cluster: NrdD anaerobic ribonucleoside triphosph... 33 4.0
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein... 33 5.3
UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar bin... 33 5.3
UniRef50_A0AYK1 Cluster: Putative uncharacterized protein; n=3; ... 32 9.3
>UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1;
n=2; Apocrita|Rep: PREDICTED: similar to cullin 1 -
Nasonia vitripennis
Length = 810
Score = 87.4 bits (207), Expect = 2e-16
Identities = 41/68 (60%), Positives = 52/68 (76%), Gaps = 2/68 (2%)
Frame = +1
Query: 394 STSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHH-- 567
S+ ++N+ L+Q D DQIWGDL+EGIEQVY +Q M K RYI+LYTHVYNYCTSVH
Sbjct: 42 SSHSSNQGPPGLKQIDLDQIWGDLKEGIEQVYNRQCMSKPRYIELYTHVYNYCTSVHQQI 101
Query: 568 HSAGSSSR 591
+S+ SS+
Sbjct: 102 NSSRQSSK 109
>UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7068,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 796
Score = 83.8 bits (198), Expect = 3e-15
Identities = 39/64 (60%), Positives = 46/64 (71%), Gaps = 2/64 (3%)
Frame = +1
Query: 403 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 576
++NR Q P LRQ DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH S
Sbjct: 2 SSNRTQNPHGLRQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSSQ 61
Query: 577 GSSS 588
G S
Sbjct: 62 GRGS 65
>UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein
isoform 3; n=1; Bos taurus|Rep: PREDICTED: hypothetical
protein isoform 3 - Bos taurus
Length = 776
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/67 (55%), Positives = 47/67 (70%), Gaps = 2/67 (2%)
Frame = +1
Query: 403 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 576
++NR Q P L+Q DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH +
Sbjct: 2 SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61
Query: 577 GSSSRVP 597
+ VP
Sbjct: 62 ARGAGVP 68
>UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -
Bos taurus (Bovine)
Length = 187
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/67 (55%), Positives = 47/67 (70%), Gaps = 2/67 (2%)
Frame = +1
Query: 403 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 576
++NR Q P L+Q DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH +
Sbjct: 2 SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61
Query: 577 GSSSRVP 597
+ VP
Sbjct: 62 ARGAGVP 68
>UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1 -
Homo sapiens (Human)
Length = 776
Score = 80.6 bits (190), Expect = 3e-14
Identities = 36/69 (52%), Positives = 47/69 (68%)
Frame = +1
Query: 391 MSTSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHH 570
MS++ + P L+Q DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH
Sbjct: 1 MSSTRSQNPH-GLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQS 59
Query: 571 SAGSSSRVP 597
+ + VP
Sbjct: 60 NQARGAGVP 68
>UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03444 protein - Schistosoma
japonicum (Blood fluke)
Length = 195
Score = 54.4 bits (125), Expect = 2e-06
Identities = 20/47 (42%), Positives = 34/47 (72%)
Frame = +1
Query: 451 IWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSSR 591
+W DL+ G + +++ + + ++RY++L+THVYNYCTSV S + SR
Sbjct: 11 VWDDLKNGFDAIFRLETIKRKRYMELHTHVYNYCTSVDPKSHTTPSR 57
>UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cullin
- Oikopleura dioica (Tunicate)
Length = 770
Score = 53.6 bits (123), Expect = 4e-06
Identities = 20/40 (50%), Positives = 30/40 (75%)
Frame = +1
Query: 445 DQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVH 564
++ W ++QEG+ V+ M +RYI+LYTHVYNYCT+V+
Sbjct: 13 ERTWAEVQEGLNNVFFHHGMGHKRYIELYTHVYNYCTAVN 52
>UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep:
Cullin-1 - Caenorhabditis elegans
Length = 780
Score = 48.8 bits (111), Expect = 1e-04
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +1
Query: 439 DFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSV 561
D + +W LQ+G++ Y+++ M + Y+ LYT VY+YCTS+
Sbjct: 12 DSEVVWKKLQDGLDVAYRRENMAPKDYMTLYTSVYDYCTSI 52
>UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|Rep:
Cullin-6 - Caenorhabditis elegans
Length = 729
Score = 46.8 bits (106), Expect = 4e-04
Identities = 17/48 (35%), Positives = 33/48 (68%)
Frame = +1
Query: 445 DQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSS 588
+ +WG LQ+G+ +Y++++M K+ Y+ LY VYN CT+ ++ ++S
Sbjct: 4 EAVWGTLQDGLNLLYRREHMSKKYYMMLYDAVYNICTTTTLANSNNNS 51
>UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 750
Score = 40.7 bits (91), Expect = 0.026
Identities = 13/42 (30%), Positives = 30/42 (71%), Gaps = 2/42 (4%)
Frame = +1
Query: 445 DQIWGDLQEGIEQVYK--KQYMVKRRYIDLYTHVYNYCTSVH 564
D++W + ++ E ++ K+ + ++RY+++YT +YNYC+S +
Sbjct: 8 DELWAECEQTFEDLFLNLKKGLSRKRYMEIYTKIYNYCSSAN 49
>UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces
pombe|Rep: Cullin-1 - Schizosaccharomyces pombe (Fission
yeast)
Length = 767
Score = 40.3 bits (90), Expect = 0.035
Identities = 19/59 (32%), Positives = 37/59 (62%), Gaps = 5/59 (8%)
Frame = +1
Query: 391 MSTSNANRPQVPLRQKDFDQI---WGDLQEGIEQVYKK--QYMVKRRYIDLYTHVYNYC 552
M+T N N +P+ +K +D + W L+ G+ Q++++ + M +Y++LYT ++NYC
Sbjct: 1 MTTLNTNDKDLPIVKK-YDSLNGTWDFLKTGVSQIFERLDEGMTITKYMELYTAIHNYC 58
>UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2;
Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 775
Score = 38.3 bits (85), Expect = 0.14
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +1
Query: 394 STSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQY--MVKRRYIDLYTHVYNYCT 555
S + + Q P + D Q W L G++ + + M YI LYT +YNYCT
Sbjct: 9 SWTEPTKAQAPPKDADLKQAWAFLSVGVDHIMTRLSFGMSYSYYILLYTAIYNYCT 64
>UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin -
Aedes aegypti (Yellowfever mosquito)
Length = 757
Score = 37.5 bits (83), Expect = 0.25
Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +1
Query: 436 KDFDQIWGDLQEGIEQVYKKQYMVK-RRYIDLYTHVYNYC 552
K D+ W L +GI ++Y+++ + R++ +T+VYNYC
Sbjct: 23 KQQDETWTKLSDGIGRLYRQEESLNLERFLQYHTYVYNYC 62
>UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involved
in cell cycle control; n=5; Saccharomycetales|Rep:
Ubiquitin ligase (Cullin) of SCF involved in cell cycle
control - Pichia stipitis (Yeast)
Length = 776
Score = 36.7 bits (81), Expect = 0.43
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Frame = +1
Query: 439 DFDQIWGDLQEGIEQVYKKQY---MVKRRYIDLYTHVYNYCTSVHHHSAGSSS 588
D + W +Q G+E + Q + + Y++ YT VYNYC + H A ++S
Sbjct: 8 DLNATWSFIQPGLEFILGAQGDQGVTPKMYMNCYTAVYNYCVNKSRHGATATS 60
>UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 724
Score = 36.3 bits (80), Expect = 0.57
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Frame = +1
Query: 415 PQVPLRQKDFDQIWGDLQEGIEQVYK--KQYMVKRRYIDLYTHVYNYCTS-------VHH 567
P P++ D D W LQ+GI + +Q + + Y+ +YT V+N+CTS +
Sbjct: 10 PMQPVKD-DIDTTWTYLQDGITMIMMNLQQGIDLQTYMGIYTAVHNFCTSQKAVGFALQS 68
Query: 568 HSAGSSSR 591
H GSS R
Sbjct: 69 HVIGSSQR 76
>UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces
cerevisiae YDL132w CDC53 controls G1/S transition; n=1;
Yarrowia lipolytica|Rep: Similar to sp|Q12018
Saccharomyces cerevisiae YDL132w CDC53 controls G1/S
transition - Yarrowia lipolytica (Candida lipolytica)
Length = 788
Score = 35.9 bits (79), Expect = 0.75
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 5/55 (9%)
Frame = +1
Query: 409 NRPQVPLRQKDFDQIWGDLQEGIEQVYKKQY-----MVKRRYIDLYTHVYNYCTS 558
N P +P R D D W +++G+ QV + + + Y++LY+ ++NYC S
Sbjct: 3 NTPPLP-RADDIDATWKYIEDGVGQVLRDDLAHGAGLSSQMYMNLYSAIHNYCVS 56
>UniRef50_A0KM85 Cluster: Putative membrane protein; n=2;
Gammaproteobacteria|Rep: Putative membrane protein -
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966
/ NCIB 9240)
Length = 357
Score = 35.5 bits (78), Expect = 0.99
Identities = 16/46 (34%), Positives = 30/46 (65%)
Frame = -3
Query: 343 FCFN*IYSLKNVSIRLLIPLQNAML*SLITSRNHSVGSDYFTLIFI 206
FC +YS++N L++ L ++ LI++ ++VGSDYF+ ++I
Sbjct: 9 FCSLYMYSVQNYKASLIVLLPPFIIYFLISALQYNVGSDYFSYLYI 54
>UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2;
Cryptosporidium|Rep: Putative uncharacterized protein -
Cryptosporidium parvum Iowa II
Length = 311
Score = 35.5 bits (78), Expect = 0.99
Identities = 13/48 (27%), Positives = 28/48 (58%)
Frame = -2
Query: 329 NIFTEKRIDPITNSVTKCNAIKLNNE*KSQCWQRLFYFNIYIT*LFVF 186
++F + PI N++ N L N+ K++ +QR YF +++ +++F
Sbjct: 195 SLFIVSKYQPIVNNIQIINIFDLANKNKNKLYQRKAYFEVFVVGIYIF 242
>UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protein,
putative; n=3; Plasmodium (Vinckeia)|Rep: Sodium/hydrogen
exchanger family protein, putative - Plasmodium yoelii
yoelii
Length = 1688
Score = 33.9 bits (74), Expect = 3.0
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 15/66 (22%)
Frame = +1
Query: 412 RPQVPLRQKDFDQI---------------WGDLQEGIEQVYKKQYMVKRRYIDLYTHVYN 546
RP++ ++ K FDQI +G L++G+ Y+KQ + K R +LY ++N
Sbjct: 1395 RPKIKIQSKQFDQIRRSRSHENYRKNKDKYGKLKDGVFHSYRKQIIRKEREGELYIMIFN 1454
Query: 547 YCTSVH 564
C ++
Sbjct: 1455 TCKELY 1460
>UniRef50_Q9V2Q2 Cluster: NrdD anaerobic ribonucleoside triphosphate
reductase; n=8; Archaea|Rep: NrdD anaerobic
ribonucleoside triphosphate reductase - Pyrococcus
abyssi
Length = 658
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Frame = +1
Query: 391 MSTSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDL---YTHVYNYCTS 558
++ + N P++ L+ +D D+ W + + +E V + RYI L Y H+Y+ T+
Sbjct: 370 INVTTVNLPRIALKARDDDEFWEEYERVLEIVRITTEWFRDRYISLIRNYPHMYSMITT 428
>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
exchanger protein - Tetrahymena thermophila SB210
Length = 5392
Score = 33.1 bits (72), Expect = 5.3
Identities = 13/41 (31%), Positives = 27/41 (65%)
Frame = +1
Query: 436 KDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTS 558
K FD+I ++ E IEQ+ K+ ++ ++ I+ ++H+ +Y S
Sbjct: 4484 KTFDEIKKNMNENIEQIKKETLLIAQKVIEDFSHLNSYYES 4524
>UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar
binding; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Glycoside hydrolase family 2, sugar binding -
Victivallis vadensis ATCC BAA-548
Length = 215
Score = 33.1 bits (72), Expect = 5.3
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +3
Query: 414 TPSAAAAKGL*SDMGRSSRGNRTSLQKTVHGQETIHRSVY 533
TP AAAKG+ +++G + +RT L T G H+ VY
Sbjct: 111 TPEQAAAKGMRAELGHINTADRTFLNGTQIGAADEHKRVY 150
>UniRef50_A0AYK1 Cluster: Putative uncharacterized protein; n=3;
Burkholderia cenocepacia|Rep: Putative uncharacterized
protein - Burkholderia cenocepacia (strain HI2424)
Length = 1140
Score = 32.3 bits (70), Expect = 9.3
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +1
Query: 448 QIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYN 546
QIWG L+ G + ++ ++Y RY+ L HV N
Sbjct: 387 QIWGFLERGHDHIFLREYSDLDRYVALNGHVSN 419
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 484,039,614
Number of Sequences: 1657284
Number of extensions: 8444995
Number of successful extensions: 20139
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 19582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 20130
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43562448615
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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