Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_J13
(787 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial acetoacetyl... 261 2e-69
D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial acetoacetyl... 261 2e-69
BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein. 152 1e-36
AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA acetyltransf... 152 1e-36
AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A acety... 151 3e-36
AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA transferase-... 151 3e-36
S70154-1|AAB30856.1| 397|Homo sapiens cytosolic acetoacetyl-coe... 149 1e-35
BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein. 122 1e-27
BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein. 122 2e-27
BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A acylt... 105 1e-22
D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-C... 104 4e-22
X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA... 77 5e-14
X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRN... 77 5e-14
X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for ... 77 5e-14
BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 77 5e-14
BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A acylt... 77 5e-14
BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 74 5e-13
D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase b... 74 7e-13
BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 74 7e-13
BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 74 7e-13
BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A ... 74 7e-13
AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein. 74 7e-13
BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein. 54 1e-11
X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase pr... 64 5e-10
U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunction... 54 6e-07
D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase b... 52 2e-06
AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens ... 41 0.006
>D90228-1|BAA14278.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase precursor protein.
Length = 427
Score = 261 bits (639), Expect = 2e-69
Identities = 127/223 (56%), Positives = 156/223 (69%)
Frame = +2
Query: 119 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 298
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 299 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 478
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 151
Query: 479 GMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQ 658
GMESMSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R +Q
Sbjct: 152 GMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 211
Query: 659 DEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 787
D YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 212 DAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254
>D10511-1|BAA01387.1| 427|Homo sapiens mitochondrial
acetoacetyl-CoA thiolase protein.
Length = 427
Score = 261 bits (639), Expect = 2e-69
Identities = 127/223 (56%), Positives = 156/223 (69%)
Frame = +2
Query: 119 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 298
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 299 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 478
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G QD+++AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 151
Query: 479 GMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQ 658
GMESMSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R +Q
Sbjct: 152 GMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 211
Query: 659 DEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 787
D YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 212 DAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254
>BC000408-1|AAH00408.1| 397|Homo sapiens ACAT2 protein protein.
Length = 397
Score = 152 bits (369), Expect = 1e-36
Identities = 83/206 (40%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +2
Query: 149 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 328
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 329 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 508
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 509 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 682
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++R+DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 683 KRSAAAYEAKAFVDELVPVPVPQKRG 760
R+ A +A F E+VPV V +RG
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRRG 212
>AB208993-1|BAD92230.1| 404|Homo sapiens Acetyl-CoA
acetyltransferase, cytosolic variant protein.
Length = 404
Score = 152 bits (369), Expect = 1e-36
Identities = 83/206 (40%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +2
Query: 149 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 328
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 15 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 74
Query: 329 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 508
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 75 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 134
Query: 509 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 682
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++R+DQD+ AV S
Sbjct: 135 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 193
Query: 683 KRSAAAYEAKAFVDELVPVPVPQKRG 760
R+ A +A F E+VPV V +RG
Sbjct: 194 NRTENAQKAGHFDKEIVPVLVSTRRG 219
>AL135914-6|CAI21850.1| 397|Homo sapiens acetyl-Coenzyme A
acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
protein.
Length = 397
Score = 151 bits (366), Expect = 3e-36
Identities = 82/206 (39%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +2
Query: 149 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 328
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 329 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 508
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 509 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 682
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++R+DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 683 KRSAAAYEAKAFVDELVPVPVPQKRG 760
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>AF356877-1|AAM00223.1| 397|Homo sapiens acetyl CoA
transferase-like protein protein.
Length = 397
Score = 151 bits (366), Expect = 3e-36
Identities = 82/206 (39%), Positives = 115/206 (55%), Gaps = 2/206 (0%)
Frame = +2
Query: 149 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 328
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 329 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 508
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 509 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 682
YL+ G G M L D I+ DGLTD ++ HMG AEN AKK Q++R+DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186
Query: 683 KRSAAAYEAKAFVDELVPVPVPQKRG 760
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>S70154-1|AAB30856.1| 397|Homo sapiens cytosolic
acetoacetyl-coenzyme A thiolase protein.
Length = 397
Score = 149 bits (360), Expect = 1e-35
Identities = 81/206 (39%), Positives = 114/206 (55%), Gaps = 2/206 (0%)
Frame = +2
Query: 149 VVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSANLGQ 328
VVI SA RT + + ++RA + E++ EV G+V +A GQ
Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
Query: 329 APARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 508
P RQA + AG+P S + +C SG+K++ LA Q + G I++AGGME+MS P
Sbjct: 68 NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
Query: 509 --YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 682
YL+ G G M L D I+ DGLTD ++ HMG AEN A K Q++R+DQD+ AV S
Sbjct: 128 LAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHMGITAENVATKWQVSREDQDKVAVLSQ 186
Query: 683 KRSAAAYEAKAFVDELVPVPVPQKRG 760
R+ A +A F E+VPV V ++G
Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTRKG 212
>BC010942-1|AAH10942.1| 162|Homo sapiens ACAT1 protein protein.
Length = 162
Score = 122 bits (295), Expect = 1e-27
Identities = 60/114 (52%), Positives = 74/114 (64%)
Frame = +2
Query: 119 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 298
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 299 GNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 460
GNV GQAP RQAV+ AGLP ST CTT+NKVCASGMK+IM+A+Q L G Q
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQ 145
>BC063853-1|AAH63853.1| 289|Homo sapiens ACAT1 protein protein.
Length = 289
Score = 122 bits (293), Expect = 2e-27
Identities = 70/165 (42%), Positives = 96/165 (58%), Gaps = 6/165 (3%)
Frame = +2
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
+ LG + A+ AG+PK +V + M +++ +G Q + +L G +
Sbjct: 64 ATKLGSIAIQGAIEKAGIPKE-------EVKEAYMGNVLQGGEG-QAPTRQAVLGAGCDG 115
Query: 491 MS------NVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQ 652
+VP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R
Sbjct: 116 GRWDGEHVHVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 175
Query: 653 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 787
+QD YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 176 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 220
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/81 (45%), Positives = 47/81 (58%)
Frame = +2
Query: 119 AFSTKVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYI 298
++ +K +L EVVI SA RTP+ + AIE+AGIPKEE+KE Y+
Sbjct: 32 SYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 91
Query: 299 GNVCSANLGQAPARQAVIFAG 361
GNV GQAP RQAV+ AG
Sbjct: 92 GNVLQGGEGQAPTRQAVLGAG 112
>BC001918-1|AAH01918.1| 397|Homo sapiens acetyl-Coenzyme A
acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A
thiolas protein.
Length = 397
Score = 105 bits (253), Expect = 1e-22
Identities = 64/210 (30%), Positives = 103/210 (49%), Gaps = 3/210 (1%)
Frame = +2
Query: 140 LNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSAN 319
L V + +A RTP AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 320 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 496
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 497 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYA 670
P+ ++ R T G ++ ++ LTD + + M AEN A K +I+R++ D+YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183
Query: 671 VNSYKRSAAAYEAKAFVDELVPVPVPQKRG 760
+ S +R AA +A F DE+ P+ V K+G
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKG 213
>D16294-1|BAA03800.1| 397|Homo sapiens mitochondrial 3-oxoacyl-CoA
thiolase protein.
Length = 397
Score = 104 bits (249), Expect = 4e-22
Identities = 63/210 (30%), Positives = 102/210 (48%), Gaps = 3/210 (1%)
Frame = +2
Query: 140 LNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVCSAN 319
L V + +A RTP AA+ + E + V +GNV ++
Sbjct: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63
Query: 320 LGQAP-ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 496
AR + G+PK T T+N++C SG +SI+ Q + +++L GG ESMS
Sbjct: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123
Query: 497 NVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYA 670
P+ ++ R T G ++ ++ LTD + + M AEN K +I+R++ D+YA
Sbjct: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLTVKHKISREECDKYA 183
Query: 671 VNSYKRSAAAYEAKAFVDELVPVPVPQKRG 760
+ S +R AA +A F DE+ P+ V K+G
Sbjct: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKG 213
>X65140-1|CAA46270.1| 424|Homo sapiens peroxisomal 3-oxoacyl-CoA
thiolase protein.
Length = 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 49/167 (29%), Positives = 89/167 (53%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 598
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 599 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
MG +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X14813-1|CAA32918.1| 424|Homo sapiens protein ( Human liver mRNA
for 3-oxoacyl-CoA thiolase. ).
Length = 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 49/167 (29%), Positives = 89/167 (53%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 598
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 599 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
MG +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>X12966-1|CAA31412.1| 424|Homo sapiens protein ( Human mRNA for
3-oxoacyl-CoA peroxisomal thiolase. ).
Length = 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 49/167 (29%), Positives = 89/167 (53%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 598
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 599 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
MG +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC011977-1|AAH11977.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 49/167 (29%), Positives = 89/167 (53%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 598
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 599 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
MG +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC000635-1|AAH00635.1| 424|Homo sapiens acetyl-Coenzyme A
acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A
thiolase) protein.
Length = 424
Score = 77.4 bits (182), Expect = 5e-14
Identities = 49/167 (29%), Positives = 89/167 (53%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKF 598
++ A G++ G+ DI +A G+ESMS RG +L++ + D
Sbjct: 129 AVASIAGGIRNGSYDIGMACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--I 179
Query: 599 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
MG +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 180 PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>BC014572-1|AAH14572.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 74.1 bits (174), Expect = 5e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLTD---VYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLASELPAVSEFSTSETMGHSA 228
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>D16481-1|BAA03942.1| 474|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of trifunctional protein protein.
Length = 474
Score = 73.7 bits (173), Expect = 7e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 48 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 107
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 108 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 272
>BC066963-1|AAH66963.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 73.7 bits (173), Expect = 7e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>BC030824-1|AAH30824.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 73.7 bits (173), Expect = 7e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>BC017564-1|AAH17564.1| 475|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenz
protein.
Length = 475
Score = 73.7 bits (173), Expect = 7e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 49 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 108
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 109 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 168
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 169 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 228
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 229 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 273
>AC010896-2|AAY14644.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 73.7 bits (173), Expect = 7e-13
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 18/226 (7%)
Frame = +2
Query: 131 KVSLNEVVIASAVRTPMXXXXXXXXXXXXXXXXXXXVNAAIERAGIPKEEIKEVYIGNVC 310
K ++ VV+ VRTP + + R +PKE + + G V
Sbjct: 48 KPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVI 107
Query: 311 SANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 490
AR+A + AG T TV C S +++ + +G D+I+AGG+E
Sbjct: 108 QEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVEL 167
Query: 491 MSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---DVYNKFH----MGNCA 616
MS+VP L + ++ + L+ F+ L ++F MG+ A
Sbjct: 168 MSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227
Query: 617 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
+ A ++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPGK 272
>BC014474-1|AAH14474.1| 331|Homo sapiens ACAA1 protein protein.
Length = 331
Score = 53.6 bits (123), Expect(2) = 1e-11
Identities = 24/84 (28%), Positives = 49/84 (58%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128
Query: 419 SIMLAAQGLQTGAQDIILAGGMES 490
++ A G++ G+ DI +A G+ S
Sbjct: 129 AVASIAGGIRNGSYDIGMACGITS 152
Score = 36.3 bits (80), Expect(2) = 1e-11
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +2
Query: 605 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 739
G +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 149 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 193
>X51460-1|CAA35825.1| 326|Homo sapiens 3-oxoacyl-CoA thiolase
protein.
Length = 326
Score = 64.1 bits (149), Expect = 5e-10
Identities = 43/135 (31%), Positives = 74/135 (54%)
Frame = +2
Query: 335 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 514
AR A + +P++ +TVN+ C+SG++++ A G++ G+ DI +A G+ESMS
Sbjct: 3 ARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LA 58
Query: 515 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 694
RG +L++ + D MG +EN A++ I+R+ QD +A+ S +++A
Sbjct: 59 DRGNPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAA 113
Query: 695 AAYEAKAFVDELVPV 739
A F E+VPV
Sbjct: 114 RAQSKGCFQAEIVPV 128
>U49441-1|AAB09424.1| 224|Homo sapiens mitochondrial trifunctional
protein beta subunit protein.
Length = 224
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 18/158 (11%)
Frame = +2
Query: 335 ARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY- 511
AR+A + AG T TV C S +++ A + +G D+++AGG+E MS+VP
Sbjct: 15 AREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRH 74
Query: 512 ----------LKRGETSYGGMQLVDGIVFDGLT-------DVYNKFHMGNCAENTAKKLQ 640
L + +T + L+ + L+ + MG+ A+ A
Sbjct: 75 SRNMRKMMLDLNKAKTLGQRLSLLSKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFA 134
Query: 641 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 754
++R +QDEYA+ S+ + A + + + ++VP VP K
Sbjct: 135 VSRMEQDEYALRSHSLAKKAQD-EGHLSDIVPFKVPGK 171
>D86850-1|BAA22061.1| 410|Homo sapiens 3-ketoacyl-CoA thiolase
beta-subunit of mitochondrial trifunctional protein
protein.
Length = 410
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/181 (25%), Positives = 83/181 (45%), Gaps = 18/181 (9%)
Frame = +2
Query: 266 IPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 445
+ + + KE G CS ++ A A + AG T TV C S +++ +
Sbjct: 30 VSQTQYKECCGGGWCSHSIF-AVWHFAALGAGFSDKTPAHTVTMACISANQAMTTGVGLI 88
Query: 446 QTGAQDIILAGGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGLT---D 583
+G D+I+AGG+E MS+VP L + ++ + L+ F+ L
Sbjct: 89 ASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELP 148
Query: 584 VYNKFH----MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQ 751
++F MG+ A+ A ++R +QDEYA+ S+ + A + + + ++VP VP
Sbjct: 149 AVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVPFKVPG 207
Query: 752 K 754
K
Sbjct: 208 K 208
>AF035295-1|AAB88181.1| 132|Homo sapiens protein ( Homo sapiens
clone 23623 mRNA, partial cds. ).
Length = 132
Score = 40.7 bits (91), Expect = 0.006
Identities = 16/62 (25%), Positives = 36/62 (58%)
Frame = +2
Query: 239 VNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMK 418
+ A ++ + E++ ++ +GNV G AR A + +P++ +TVN+ C+SG++
Sbjct: 48 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 107
Query: 419 SI 424
++
Sbjct: 108 AV 109
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,293,590
Number of Sequences: 237096
Number of extensions: 2143737
Number of successful extensions: 7750
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 7553
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7743
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9590293096
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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