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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P01_F_H05
         (644 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P36188 Cluster: Troponin I; n=50; cellular organisms|Re...   165   1e-39
UniRef50_Q9XUN9 Cluster: Troponin I 3; n=6; Caenorhabditis|Rep: ...    91   2e-17
UniRef50_Q5DDC3 Cluster: SJCHGC00516 protein; n=4; Schistosoma j...    70   6e-11
UniRef50_Q7M3Y3 Cluster: Troponin I; n=5; Pectinidae|Rep: Tropon...    60   4e-08
UniRef50_UPI0000E48440 Cluster: PREDICTED: similar to troponin I...    58   2e-07
UniRef50_P50754 Cluster: Troponin I, cardiac muscle; n=18; Tetra...    55   2e-06
UniRef50_P19429 Cluster: Troponin I, cardiac muscle; n=108; Chor...    53   7e-06
UniRef50_Q9NDR9 Cluster: Troponin I; n=1; Branchiostoma belcheri...    50   4e-05
UniRef50_Q8WPC1 Cluster: Adult cardiac troponin I; n=9; Ascidiac...    50   4e-05
UniRef50_Q71N42 Cluster: Fast muscle troponin I; n=31; Euteleost...    50   5e-05
UniRef50_P48788 Cluster: Troponin I, fast skeletal muscle; n=15;...    48   1e-04
UniRef50_P45379 Cluster: Troponin T, cardiac muscle; n=294; Eute...    45   0.001
UniRef50_Q4RGJ7 Cluster: Chromosome undetermined SCAF15099, whol...    42   0.013
UniRef50_Q25148 Cluster: Troponin T; n=2; Halocynthia roretzi|Re...    40   0.068
UniRef50_P45378 Cluster: Troponin T, fast skeletal muscle; n=64;...    39   0.12 
UniRef50_Q5CUD2 Cluster: Uncharacterized protein with several co...    34   2.6  
UniRef50_A2E6E9 Cluster: PIKK family atypical protein kinase; n=...    34   3.4  
UniRef50_Q54U84 Cluster: Putative uncharacterized protein; n=1; ...    33   4.5  
UniRef50_Q6C3Y3 Cluster: Similar to tr|Q12191 Saccharomyces cere...    33   5.9  
UniRef50_UPI00006CC4C7 Cluster: hypothetical protein TTHERM_0013...    33   7.8  
UniRef50_Q759L7 Cluster: ADR259Wp; n=1; Eremothecium gossypii|Re...    33   7.8  

>UniRef50_P36188 Cluster: Troponin I; n=50; cellular organisms|Rep:
           Troponin I - Drosophila melanogaster (Fruit fly)
          Length = 269

 Score =  165 bits (400), Expect = 1e-39
 Identities = 87/184 (47%), Positives = 102/184 (55%)
 Frame = +3

Query: 93  NTTTMADDEANKAKQAEIDRKRAEVRKRMEEASXXXXXXXGFMTPXXXXXXXXXXXXXXX 272
           N   +  +EA KAKQAEI+RKRAEVRKRMEEAS       GFMTP               
Sbjct: 58  NDPKVKAEEAKKAKQAEIERKRAEVRKRMEEASKAKKAKKGFMTPERKKKLRLLLRKKAA 117

Query: 273 XXXXXXXXXXXXXXXXXXXXXCGKPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERA 452
                                CG P+N+ DA+E ELQ IC+ Y+ R+Y  EG K++LE  
Sbjct: 118 EELKKEQERKAAERRRIIEERCGSPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYE 177

Query: 453 IEIRKMEISDLNSQVNDLRGKFVKPTLKKVSKYXXXXXXXXXXXXXXXXRNQLKVVKXKE 632
           +  +  EI+DLN+QVNDLRGKFVKP LKKVSKY                RNQLKVVK KE
Sbjct: 178 VRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQKKAAEFNFRNQLKVVKKKE 237

Query: 633 FTLE 644
           FTLE
Sbjct: 238 FTLE 241


>UniRef50_Q9XUN9 Cluster: Troponin I 3; n=6; Caenorhabditis|Rep:
           Troponin I 3 - Caenorhabditis elegans
          Length = 260

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
 Frame = +3

Query: 111 DDEANKAKQAEIDRKRAEVRKRMEEASXXXXXXXGFMTPXXXXXXXXXXXXXXXXXXXXX 290
           DD A KA++ E+  K+AEVRKRMEEA+       GF+TP                     
Sbjct: 19  DDAARKAQEREL--KKAEVRKRMEEAAKKGSKKKGFLTPERKKKLRKLLMMKAAEDLKQQ 76

Query: 291 XXXXXXXXXXXXXXXCGKPKNIDDANE-AELQTICQMYWHRIYNLEGDKYELERAIEIRK 467
                               ++D  N+  +L  I +  + R+  LE +K+++   +   +
Sbjct: 77  QMLKEQERQKTLQQRTIPLPDVDSINDQGQLLKIYEDMFARVCALEEEKFDINFGVSQTE 136

Query: 468 MEISDLNSQVNDLRGKFVKPTLKKVSKYXXXXXXXXXXXXXXXXRNQLKVVKXKEFTLE 644
            EI+ L  QVNDLRGKFVKPTLKKVSKY                RN LKVVK KE  L+
Sbjct: 137 AEINQLTIQVNDLRGKFVKPTLKKVSKYDNKFKSSGEVKEKSNFRNNLKVVK-KETDLD 194


>UniRef50_Q5DDC3 Cluster: SJCHGC00516 protein; n=4; Schistosoma
           japonicum|Rep: SJCHGC00516 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 221

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           +P  +D   E +L    +  + R+  LEGDKY+ E  +  +  EI++L  +VND++GKFV
Sbjct: 108 EPLKLDGLGENDLNAKVKQLYERVRQLEGDKYDWEEKLRRQDFEINELTIKVNDVKGKFV 167

Query: 522 KPTLKKVSK---YXXXXXXXXXXXXXXXXRNQLKVVKXKEFTLE 644
           KP LKKVSK   +                RNQLK     ++ LE
Sbjct: 168 KPVLKKVSKTESHMARFEKKEGGHSLSSFRNQLKSTGHSKYALE 211


>UniRef50_Q7M3Y3 Cluster: Troponin I; n=5; Pectinidae|Rep: Troponin
           I - Chlamys nipponensis akazara (Akazara scallop)
           (Japanese scallop)
          Length = 292

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
 Frame = +3

Query: 345 PK-NIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           PK + D  + A LQ +C+ +  R+ +LE D Y+ E  I  +  EI++L  +VND +GKFV
Sbjct: 184 PKFSTDGKDVAALQALCKDFHKRLASLEEDVYDWEAKIRKQDFEINELTLKVNDTKGKFV 243

Query: 522 KPTLKKVSK 548
           KP L+KV+K
Sbjct: 244 KPVLRKVNK 252


>UniRef50_UPI0000E48440 Cluster: PREDICTED: similar to troponin I,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to troponin I, partial -
           Strongylocentrotus purpuratus
          Length = 312

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 25/69 (36%), Positives = 43/69 (62%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           KP +ID  +   L+ +C+    ++ + EG+K++LE  I  + +EI D+  + N+ RGKF 
Sbjct: 230 KPLSIDSLSRDRLRALCEELTEQLTDAEGNKFDLEVIIRKQDLEIEDMKVRANEARGKFE 289

Query: 522 KPTLKKVSK 548
           +P LKKV +
Sbjct: 290 RPELKKVQR 298


>UniRef50_P50754 Cluster: Troponin I, cardiac muscle; n=18;
           Tetrapoda|Rep: Troponin I, cardiac muscle - Xenopus
           laevis (African clawed frog)
          Length = 244

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 24/67 (35%), Positives = 41/67 (61%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           +P  +   + +ELQ +CQ    RI  ++ ++Y++E  +     E+ DLN ++ DLRGKF 
Sbjct: 106 QPLQLSGLSRSELQDLCQELHARIDVVDEERYDMEAKVNKNITELEDLNQKIFDLRGKFK 165

Query: 522 KPTLKKV 542
           KP L++V
Sbjct: 166 KPNLRRV 172


>UniRef50_P19429 Cluster: Troponin I, cardiac muscle; n=108;
           Chordata|Rep: Troponin I, cardiac muscle - Homo sapiens
           (Human)
          Length = 210

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 23/67 (34%), Positives = 41/67 (61%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           +P  +     AELQ +C+    R+  ++ ++Y++E  +     EI+DL  ++ DLRGKF 
Sbjct: 81  QPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFK 140

Query: 522 KPTLKKV 542
           +PTL++V
Sbjct: 141 RPTLRRV 147


>UniRef50_Q9NDR9 Cluster: Troponin I; n=1; Branchiostoma
           belcheri|Rep: Troponin I - Branchiostoma belcheri
           (Amphioxus)
          Length = 180

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 22/56 (39%), Positives = 36/56 (64%)
 Frame = +3

Query: 375 ELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKPTLKKV 542
           EL+ +C+    +I   E +KY++E+ +EI   E++DL  ++  L GKF KP LK+V
Sbjct: 60  ELEELCRRLHAQITKAEEEKYDVEQKVEINDKELADLTQRMYSLTGKFKKPQLKRV 115


>UniRef50_Q8WPC1 Cluster: Adult cardiac troponin I; n=9;
           Ascidiacea|Rep: Adult cardiac troponin I - Halocynthia
           roretzi (Sea squirt)
          Length = 260

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 21/64 (32%), Positives = 39/64 (60%)
 Frame = +3

Query: 351 NIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKPT 530
           N+   +E +L+ +C+    +I  ++  +Y++E  +     EI DLN ++ DLRGKF +P 
Sbjct: 132 NLGGMSEQDLKDLCRELHAKIEKVDEQRYDIEVKVNKNDQEIEDLNQRIFDLRGKFKRPP 191

Query: 531 LKKV 542
           L++V
Sbjct: 192 LRRV 195


>UniRef50_Q71N42 Cluster: Fast muscle troponin I; n=31;
           Euteleostomi|Rep: Fast muscle troponin I - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 176

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 23/56 (41%), Positives = 35/56 (62%)
 Frame = +3

Query: 375 ELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKPTLKKV 542
           ELQ +C+    +I  ++ ++Y++E  +     EI DL  +V DL+GKF KP LKKV
Sbjct: 56  ELQDLCKKLHQQIDKVDEERYDMEAKVAKADKEIEDLKVKVIDLKGKFKKPALKKV 111


>UniRef50_P48788 Cluster: Troponin I, fast skeletal muscle; n=15;
           Eutheria|Rep: Troponin I, fast skeletal muscle - Homo
           sapiens (Human)
          Length = 182

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 20/57 (35%), Positives = 37/57 (64%)
 Frame = +3

Query: 372 AELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKPTLKKV 542
           +E+Q +C+    +I   E +KY++E  ++    E+ D+N ++ DLRGKF +P L++V
Sbjct: 59  SEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRV 115


>UniRef50_P45379 Cluster: Troponin T, cardiac muscle; n=294;
           Euteleostomi|Rep: Troponin T, cardiac muscle - Homo
           sapiens (Human)
          Length = 298

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 19/50 (38%), Positives = 32/50 (64%)
 Frame = +3

Query: 354 IDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVND 503
           ID  NE +L+   +  W  IYNLE +K++L+   + +K EI+ L +++ND
Sbjct: 231 IDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIND 280


>UniRef50_Q4RGJ7 Cluster: Chromosome undetermined SCAF15099, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF15099, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 334

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 18/69 (26%), Positives = 41/69 (59%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFV 521
           KP N+D+ ++ +L+   +  W  +YNLE  K++    ++ ++ E+  L +++++L+    
Sbjct: 262 KPLNVDNLSDDKLRETAKELWELLYNLEEIKFDHCEKLKRQRYEVISLRNRIDELQKHLE 321

Query: 522 KPTLKKVSK 548
           K T+ K +K
Sbjct: 322 KMTVGKKNK 330


>UniRef50_Q25148 Cluster: Troponin T; n=2; Halocynthia roretzi|Rep:
           Troponin T - Halocynthia roretzi (Sea squirt)
          Length = 248

 Score = 39.5 bits (88), Expect = 0.068
 Identities = 17/58 (29%), Positives = 34/58 (58%)
 Frame = +3

Query: 351 NIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVK 524
           ++D  +  +L+   Q  W  +Y+LE +K + E  I+ +K +++ L  +VN+  GK+ K
Sbjct: 170 SVDHLSPDKLREKAQELWDLLYSLEEEKIDYEVRIDRQKYDLNQLRQRVNEYMGKYSK 227


>UniRef50_P45378 Cluster: Troponin T, fast skeletal muscle; n=64;
           Euteleostomi|Rep: Troponin T, fast skeletal muscle -
           Homo sapiens (Human)
          Length = 269

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 17/53 (32%), Positives = 31/53 (58%)
 Frame = +3

Query: 342 KPKNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVN 500
           KP NID   E +L+   +  W  ++ LE DK+E    ++ +K +I+ L S+++
Sbjct: 195 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRID 247


>UniRef50_Q5CUD2 Cluster: Uncharacterized protein with several
           coiled coil regions; n=2; Cryptosporidium|Rep:
           Uncharacterized protein with several coiled coil regions
           - Cryptosporidium parvum Iowa II
          Length = 719

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = +3

Query: 375 ELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKPTLKK 539
           EL   C  Y   + N+E + YEL + I I + EIS L  +  +L  K    T +K
Sbjct: 430 ELFQKCTEYTTNVQNIEAENYELSKKISILEDEISFLREKNEELLNKIEDDTKEK 484


>UniRef50_A2E6E9 Cluster: PIKK family atypical protein kinase; n=2;
            Eukaryota|Rep: PIKK family atypical protein kinase -
            Trichomonas vaginalis G3
          Length = 2195

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 16/44 (36%), Positives = 23/44 (52%)
 Frame = +3

Query: 360  DANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNS 491
            D  E ++  I Q +  R+ N+ GD Y   R  EIR M I+  N+
Sbjct: 1368 DYKEGKVNNISQRWERRLNNISGDSYSWMRLAEIRSMIINPTNN 1411


>UniRef50_Q54U84 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 674

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 17/53 (32%), Positives = 28/53 (52%)
 Frame = +3

Query: 360 DANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKF 518
           D N+     + Q     I+NL+   YE ++ IE ++  I DLN ++N L+  F
Sbjct: 96  DYNKTIYSEVLQEKDQHIFNLKNKNYEQQKLIENQQDLIRDLNRKINSLKINF 148


>UniRef50_Q6C3Y3 Cluster: Similar to tr|Q12191 Saccharomyces
           cerevisiae YDL099w; n=1; Yarrowia lipolytica|Rep:
           Similar to tr|Q12191 Saccharomyces cerevisiae YDL099w -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 337

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +3

Query: 90  TNTTTMADDEANKAKQAEIDRKRAEVRKRMEE 185
           T+TT M+D+E   A   E D K A  +KR EE
Sbjct: 15  TSTTIMSDEEVKNASGGEEDEKLAAAKKRFEE 46


>UniRef50_UPI00006CC4C7 Cluster: hypothetical protein
           TTHERM_00138580; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00138580 - Tetrahymena
           thermophila SB210
          Length = 1398

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 16/64 (25%), Positives = 34/64 (53%)
 Frame = +3

Query: 348 KNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKP 527
           KN+D+  +  +Q +CQM      + E  K  L + I+   +E S+ N ++N  R ++++ 
Sbjct: 466 KNVDEQEKMNMQVLCQMVMDSGMSAEDQKRALMK-IQQLYLESSNGNGEINQERQRYIQQ 524

Query: 528 TLKK 539
            + +
Sbjct: 525 MMNQ 528


>UniRef50_Q759L7 Cluster: ADR259Wp; n=1; Eremothecium gossypii|Rep:
           ADR259Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 409

 Score = 32.7 bits (71), Expect = 7.8
 Identities = 20/67 (29%), Positives = 32/67 (47%)
 Frame = +3

Query: 348 KNIDDANEAELQTICQMYWHRIYNLEGDKYELERAIEIRKMEISDLNSQVNDLRGKFVKP 527
           KN+D  +E EL     MY H    L  DK EL+  I  R  +IS     + + + K +  
Sbjct: 187 KNVDSRSEVELNLSKHMYEHVKCKLNIDKQELKEQIRTRDHKISKYRDTIME-KNKQINR 245

Query: 528 TLKKVSK 548
            ++ ++K
Sbjct: 246 LMRILNK 252


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 466,382,796
Number of Sequences: 1657284
Number of extensions: 7069099
Number of successful extensions: 23889
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 23064
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23881
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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