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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P01_F_G23
         (655 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P33993 Cluster: DNA replication licensing factor MCM7; ...   219   5e-56
UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n...   119   7e-26
UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep:...   118   9e-26
UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7, ...    92   9e-18
UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium ...    89   1e-16
UniRef50_Q5DG64 Cluster: SJCHGC09554 protein; n=1; Schistosoma j...    83   4e-15
UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor...    82   1e-14
UniRef50_P38132 Cluster: DNA replication licensing factor CDC47;...    75   1e-12
UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, wh...    74   3e-12
UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7 homol...    73   5e-12
UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota...    73   8e-12
UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE...    72   1e-11
UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7...    66   5e-10
UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47...    56   6e-07
UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6; ...    53   7e-06
UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/...    51   2e-05
UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mc...    50   4e-05
UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;...    36   2e-04
UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;...    46   0.001
UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase, minich...    46   0.001
UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Re...    44   0.003
UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme...    43   0.006
UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1; ...    43   0.006
UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum lac...    43   0.006
UniRef50_P53091 Cluster: DNA replication licensing factor MCM6; ...    43   0.006
UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomon...    43   0.007
UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1; ...    43   0.007
UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n...    42   0.013
UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM re...    42   0.017
UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=...    40   0.039
UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium ...    40   0.039
UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, wh...    40   0.039
UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermu...    40   0.039
UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-l...    40   0.052
UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7 ...    40   0.052
UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep:...    40   0.052
UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1; Natron...    40   0.052
UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance pr...    40   0.052
UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1; Haloqu...    40   0.069
UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta t...    40   0.069
UniRef50_Q22D74 Cluster: Putative uncharacterized protein; n=1; ...    39   0.091
UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6, ...    39   0.091
UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1; ...    39   0.091
UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489...    39   0.091
UniRef50_P49731 Cluster: DNA replication licensing factor mcm6; ...    39   0.091
UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3 h...    39   0.091
UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole geno...    39   0.12 
UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE...    39   0.12 
UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6 ...    39   0.12 
UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing fac...    39   0.12 
UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus lu...    38   0.16 
UniRef50_UPI000049A27A Cluster: DNA replication licensing factor...    38   0.21 
UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lambl...    38   0.21 
UniRef50_Q4Q826 Cluster: DNA replication licensing factor, putat...    38   0.21 
UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2...    38   0.21 
UniRef50_Q979U9 Cluster: DNA replication initiator; n=4; Thermop...    38   0.21 
UniRef50_P30666 Cluster: DNA replication licensing factor mcm3; ...    38   0.21 
UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM...    38   0.28 
UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lambli...    38   0.28 
UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomon...    38   0.28 
UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of str...    38   0.28 
UniRef50_Q5HCB0 Cluster: Putative uncharacterized protein Erum06...    37   0.37 
UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7; ...    37   0.37 
UniRef50_A7S8B1 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ...    37   0.37 
UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2; ...    37   0.37 
UniRef50_UPI00006CFD9E Cluster: conserved hypothetical protein; ...    37   0.49 
UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14;...    37   0.49 
UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia b...    36   0.64 
UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus tropica...    36   0.85 
UniRef50_Q8ILG6 Cluster: Coatamer protein, beta subunit, putativ...    36   0.85 
UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 l...    36   0.85 
UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, wh...    36   0.85 
UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;...    36   0.85 
UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing fact...    36   0.85 
UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/...    36   1.1  
UniRef50_UPI0000499A20 Cluster: hypothetical protein 53.t00045; ...    35   1.5  
UniRef50_A3DIH5 Cluster: Radical SAM; n=1; Clostridium thermocel...    35   1.5  
UniRef50_A0YYA0 Cluster: Putative uncharacterized protein; n=2; ...    35   2.0  
UniRef50_Q54H83 Cluster: Putative uncharacterized protein; n=1; ...    35   2.0  
UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomon...    35   2.0  
UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1; ...    34   2.6  
UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome s...    34   3.4  
UniRef50_Q5TN00 Cluster: ENSANGP00000028786; n=4; Culicidae|Rep:...    34   3.4  
UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1; ...    34   3.4  
UniRef50_P49736 Cluster: DNA replication licensing factor MCM2; ...    34   3.4  
UniRef50_Q6KD52 Cluster: Putative uncharacterized protein; n=4; ...    33   4.5  
UniRef50_A7HCY8 Cluster: Heavy metal efflux pump, CzcA family; n...    33   4.5  
UniRef50_Q9VDT2 Cluster: CG17186-PA; n=1; Drosophila melanogaste...    33   4.5  
UniRef50_A0DPP4 Cluster: Chromosome undetermined scaffold_59, wh...    33   4.5  
UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured hal...    33   4.5  
UniRef50_UPI000058665D Cluster: PREDICTED: similar to LOC495125 ...    33   6.0  
UniRef50_Q91GJ2 Cluster: Putative uncharacterized protein; n=1; ...    33   6.0  
UniRef50_Q54S44 Cluster: Putative uncharacterized protein; n=2; ...    33   6.0  
UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme...    33   6.0  
UniRef50_Q5V011 Cluster: MCM / cell division control protein 21;...    33   6.0  
UniRef50_A3CTI4 Cluster: CRISPR-associated protein Cas1; n=1; Me...    33   6.0  
UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1; Te...    33   7.9  
UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome s...    33   7.9  
UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whol...    33   7.9  
UniRef50_Q6JT33 Cluster: NADH-ubiquinone oxidoreductase chain 1;...    33   7.9  
UniRef50_A5K611 Cluster: DNA replication licensing factor, putat...    33   7.9  
UniRef50_Q6BT17 Cluster: Similar to CA1866|IPF7647 Candida albic...    33   7.9  
UniRef50_P24279 Cluster: DNA replication licensing factor MCM3; ...    33   7.9  

>UniRef50_P33993 Cluster: DNA replication licensing factor MCM7;
           n=52; Eukaryota|Rep: DNA replication licensing factor
           MCM7 - Homo sapiens (Human)
          Length = 719

 Score =  219 bits (535), Expect = 5e-56
 Identities = 102/185 (55%), Positives = 139/185 (75%)
 Frame = +1

Query: 100 MAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE 279
           MA++DY  +KE  K F  +F Q D+ GKK FKY  QL ++AHREQ+A  VDLDD+ E + 
Sbjct: 1   MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP 60

Query: 280 DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEM 459
           +L +++ +N RRY  + +D V E+LP YK +EVV KD LDVYIEHR+M+E R+ R PG +
Sbjct: 61  ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRS-RDPGMV 119

Query: 460 RDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVV 639
           R P+N+YP EL+RRFE+YF+  S++K   IREV+A+ +GKL TVRGIVTR ++VKP +VV
Sbjct: 120 RSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVV 179

Query: 640 ATYSC 654
           ATY+C
Sbjct: 180 ATYTC 184


>UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n=6;
           Dikarya|Rep: ATP dependent DNA helicase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 788

 Score =  119 bits (286), Expect = 7e-26
 Identities = 62/161 (38%), Positives = 95/161 (59%), Gaps = 2/161 (1%)
 Frame = +1

Query: 178 GKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLT--EAVKQNTRRYTNMVSDVVYEM 351
           G+  FKY   L +VA+R +    +DL DL   + DL+    ++ NTRRY  + SDV+ ++
Sbjct: 78  GRTKFKYLRMLREVANRRREDIVIDLKDLKRHSNDLSLLHNIQNNTRRYIQLFSDVIDKI 137

Query: 352 LPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLST 531
           +P    +     D LD+ ++ R  + A+     GE       +PPEL+RR+ VYF+ L +
Sbjct: 138 MPPPDNEVDYTDDVLDLIMQQRREMNAQVEA--GERNADAGMFPPELMRRYNVYFRPLRS 195

Query: 532 SKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
              + +R V+  H+GKL TVRGIVTR ++VKPLL+V  Y+C
Sbjct: 196 DDVLAVRAVRGAHLGKLITVRGIVTRVSEVKPLLIVNAYTC 236


>UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep:
           Protein PROLIFERA - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 716

 Score =  118 bits (285), Expect = 9e-26
 Identities = 74/188 (39%), Positives = 104/188 (55%), Gaps = 3/188 (1%)
 Frame = +1

Query: 100 MAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE 279
           M   D+  DK   K F  +F   D  G+   KY E L +V++R+  A +VDLDDL    +
Sbjct: 1   MKDHDFDGDKGLAKGFLENFA--DANGRS--KYMEILQEVSNRKIRAIQVDLDDLFNYKD 56

Query: 280 DLTE---AVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIP 450
           +  E    + +NTRRY ++ S  V E+LP+    E    D  D+ +  R    A +    
Sbjct: 57  ESEEFLGRLTENTRRYVSIFSAAVDELLPEPT--EAFPDDDHDILMTQR----ADDGTDN 110

Query: 451 GEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPL 630
            ++ DP  + P E+ R +EVYFK  S  +   IREVKA HIG+L  + GIVTRC+DVKPL
Sbjct: 111 PDVSDPHQQIPSEIKRYYEVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPL 170

Query: 631 LVVATYSC 654
           + VA Y+C
Sbjct: 171 MAVAVYTC 178


>UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7,
           putative; n=10; Ascomycota|Rep: DNA replication
           licensing factor Mcm7, putative - Aspergillus fumigatus
           (Sartorya fumigata)
          Length = 854

 Score = 92.3 bits (219), Expect = 9e-18
 Identities = 64/174 (36%), Positives = 97/174 (55%), Gaps = 20/174 (11%)
 Frame = +1

Query: 193 KYAEQLTKVAHREQIAFEVDLDDL----HEMNED----LTEAVKQNTRRYTNMVSDVVYE 348
           KY + L  +A RE+    ++LDDL      + ED    L E++++NT+RY ++ SD V  
Sbjct: 82  KYMQILQDIADRERSNVLIELDDLATFEKSLPEDTDLKLVESIQRNTKRYIDVFSDAVDA 141

Query: 349 MLPDYKFKEVVAKDS-LDVYIEHRIML-EARNHRIPGEMRDPR--NRYPPELIRRFEVYF 516
           ++P  + KE+  KD  LDV +  R    EA       +M      + +PPEL RR+ + F
Sbjct: 142 VMPK-ETKEITFKDDVLDVIMSQREKRNEAMAMAAEADMDAAAAPSMFPPELTRRYTLNF 200

Query: 517 KDLSTS--------KSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           K L+ S        K++ +R V+AEH+G L TVRGI TR +DVKP + +  Y+C
Sbjct: 201 KPLTPSGSSSDRYSKALAVRNVRAEHLGSLITVRGITTRVSDVKPSVQINAYTC 254


>UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium
           discoideum AX4|Rep: MCM family protein - Dictyostelium
           discoideum AX4
          Length = 789

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 63/208 (30%), Positives = 106/208 (50%), Gaps = 27/208 (12%)
 Frame = +1

Query: 112 DYTADKESFKNFFVDFCQTDDEGKKYF-KYAEQLTKVAHREQIAFEVDLDDLHEMNEDLT 288
           DY ++KE  K+F   F  TD+     F KY E + ++  R++  F+++LDD++  N DL 
Sbjct: 47  DYLSEKEKCKDFLNFFKCTDNGNIGGFEKYVEMMKEITQRKRKNFDIELDDVYNFNRDLV 106

Query: 289 --EAVKQNTRRYTNMVSDVVYEML--PDYKFKEVVA-----------KDSLDVYIEHRIM 423
             E+++  T  Y  + +  + E++  PD                   K+    Y    ++
Sbjct: 107 FVESIENQTSTYLRLFTYALDELIPPPDLSSTRSAMGFNNDDGFDKNKEDQKFYQNSDMV 166

Query: 424 LEA-RNHRIPGE-MRDPRNR---------YPPELIRRFEVYFKDLSTSKSVPIREVKAEH 570
           L+   + RI  +     +NR         +P E+IRRFE++F        +PIR +++E 
Sbjct: 167 LDLLASQRIQRKKFLQEQNRLDLDSNEFDFPQEIIRRFELHFIPRKGKSIIPIRLIRSEL 226

Query: 571 IGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IG+L T  G+VTR TDVKPL+V++ Y+C
Sbjct: 227 IGRLVTFSGVVTRVTDVKPLVVISLYTC 254


>UniRef50_Q5DG64 Cluster: SJCHGC09554 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC09554 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 135

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 38/69 (55%), Positives = 48/69 (69%)
 Frame = +1

Query: 448 PGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKP 627
           P  M + R+R+PPEL+RRFEVYF   S  K + +R V A  IG L  VRG+VTR T+VKP
Sbjct: 23  PVNMAEVRSRFPPELLRRFEVYFCGRSDKKPLSVRNVLASSIGHLIQVRGVVTRATEVKP 82

Query: 628 LLVVATYSC 654
           L+  ATY+C
Sbjct: 83  LITTATYTC 91


>UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
           replication licensing factor - Entamoeba histolytica
           HM-1:IMSS
          Length = 690

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 55/183 (30%), Positives = 90/183 (49%), Gaps = 6/183 (3%)
 Frame = +1

Query: 124 DKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNED------L 285
           DK + ++F   +  +D  G  Y    EQ+          F  D+ D   +N++      +
Sbjct: 29  DKITIEHFLTTYVLSD--GSTYKSRLEQINIQRDGNFTIFLDDVKDYLSLNDNQIKDKKI 86

Query: 286 TEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRD 465
            + ++ N  RY N+  +V+Y +LP     +  + DS+DV     + ++    ++      
Sbjct: 87  LDRIESNAARYLNIFKEVIYTLLPSRVGLDPSSLDSVDV-----LTIQRETKKL------ 135

Query: 466 PRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVAT 645
               +P EL  +FE + +     +  PIRE++AE IGKL  V+GIVTR TDV+PL  V T
Sbjct: 136 ---SFPLELKAKFETFIRPRKNQEITPIRELRAEKIGKLVRVKGIVTRATDVRPLARVIT 192

Query: 646 YSC 654
           YSC
Sbjct: 193 YSC 195


>UniRef50_P38132 Cluster: DNA replication licensing factor CDC47;
           n=21; Eukaryota|Rep: DNA replication licensing factor
           CDC47 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 845

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 66/202 (32%), Positives = 94/202 (46%), Gaps = 48/202 (23%)
 Frame = +1

Query: 193 KYAEQLTKVAHREQIAFEVDLDD-LHEMNE---------DLTEAVKQNTRRYTNMVSDVV 342
           KY   L KVA+RE  +  +DLDD L   NE         DL  A++QN   +T +    +
Sbjct: 62  KYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAI 121

Query: 343 YEMLPDYKFKEVVAKDS-LDVYIEHRI-----MLEARNHRIPGE---------------- 456
              +P    KE+  KD  LDV +  R      ML  R + I  E                
Sbjct: 122 DNNMP-LPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180

Query: 457 ----MRDPRNRYPPELIRRFEVYFKDLS------------TSKSVPIREVKAEHIGKLXT 588
               + D    +PP L RR+ +YFK LS            +SK + +R++K + +G+L T
Sbjct: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240

Query: 589 VRGIVTRCTDVKPLLVVATYSC 654
           VRGI+TR +DVKP + V  Y+C
Sbjct: 241 VRGIITRVSDVKPAVEVIAYTC 262


>UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_43,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 745

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 50/190 (26%), Positives = 98/190 (51%), Gaps = 9/190 (4%)
 Frame = +1

Query: 112 DYTADKESFKNFFVDFCQTD----DEGKKYFKYAEQLTKVAHREQIAFEVDLDDL-HEMN 276
           +Y ++  S   F  +F        D      KY  +L ++A+R+    ++ ++DL +  N
Sbjct: 14  EYASELSSLSEFLAEFRDNSIVEIDNTYGQRKYMIELQRIANRQTNRIDIYVEDLEYFFN 73

Query: 277 E--DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIP 450
           +  D    +K NT  Y  ++ D    ++P  + ++   + + D++ E   +   +N    
Sbjct: 74  DRIDFVNKIKTNTLSYQRLLYDACDTLMPQ-QTRDF--EQNFDLFDEEINVQRQQNMEQD 130

Query: 451 GEMRDPRNRYPPELIRRFEVYF-KDLSTSKSV-PIREVKAEHIGKLXTVRGIVTRCTDVK 624
           G   + + R PPELIRR++++  +   T + V  IR +KA+ IG L T++ +V R ++V+
Sbjct: 131 GN-NNHQKRLPPELIRRYQLFIIRGPQTKQQVMAIRNLKAQLIGSLITIKAMVVRTSEVR 189

Query: 625 PLLVVATYSC 654
           P ++VA +SC
Sbjct: 190 PQIIVACFSC 199


>UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7
           homologue; n=1; Ostreococcus tauri|Rep: Replication
           licensing factor MCM7 homologue - Ostreococcus tauri
          Length = 354

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 48/190 (25%), Positives = 90/190 (47%), Gaps = 5/190 (2%)
 Frame = +1

Query: 100 MAMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE 279
           M+   Y  D+E  + F     +T   G     Y   + ++  R+  + +++L  + E +E
Sbjct: 45  MSEEVYAHDRELIRGFL----ETFKSGAAKPLYIIAMQEIIDRQSCSMQIELQHVKEFSE 100

Query: 280 ----DLTEAVKQNTRRYTNMVSDVVYEMLPDY-KFKEVVAKDSLDVYIEHRIMLEARNHR 444
                L   V  N +RY+ + ++ + +++    +   +   D+ D+ + H          
Sbjct: 101 AERDQLVRRVVSNCKRYSTIFAEEIDKIMARMIESSSMHPDDTADIVLRHHFGDHRNGSA 160

Query: 445 IPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVK 624
            PG +R           R F+V+FK  + +  + +RE++A+ IGK  T +G+ TR TDVK
Sbjct: 161 APGSLR-----------RHFDVFFKPATGTTPIKMREIRAKMIGKYVTFKGMCTRLTDVK 209

Query: 625 PLLVVATYSC 654
           PL+ VA Y+C
Sbjct: 210 PLMEVACYTC 219


>UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota|Rep:
            MCM2/3/5 family protein - Tetrahymena thermophila SB210
          Length = 1681

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 48/164 (29%), Positives = 87/164 (53%), Gaps = 10/164 (6%)
 Frame = +1

Query: 193  KYAEQLTKVAHREQIAFEVDLDDLHEM-----NEDLTEAVKQNTRRYTNMVSDVVYEMLP 357
            KY   L +VA+ +    ++ ++DL E      +  L +A+++NT R+ +++S V   ++P
Sbjct: 971  KYMNLLQRVANNQDSRVDILMEDLEEYFKSEKDRPLIDAIQRNTSRFVDILSKVCDTVMP 1030

Query: 358  DYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMR---DPRNRYPPELIRRFEVYF--KD 522
                + V      ++    +I+ + R   + G+     + +NR  P L R+F+++     
Sbjct: 1031 A---RNVPMTSDEEMENMQQILNDQRMSNMEGDQNKDDNVKNRLNPLLNRKFQLFIIRGP 1087

Query: 523  LSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
             S  K  PIR +K+E IG L T++ IV R +DVKP++ VA Y C
Sbjct: 1088 DSKQKITPIRNLKSEDIGGLVTIKAIVIRTSDVKPMMQVACYIC 1131


>UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
           MCM FAMILY MCM7; n=1; Encephalitozoon cuniculi|Rep: DNA
           REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM7 -
           Encephalitozoon cuniculi
          Length = 694

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 53/182 (29%), Positives = 89/182 (48%), Gaps = 1/182 (0%)
 Frame = +1

Query: 112 DYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNED-LT 288
           DY ADK+    F + F + D E      YA +L +       + E+D++D+   +E  L 
Sbjct: 15  DYQADKDRLSKFLL-FHEEDGE----LTYANRLREAGG----SVEIDMEDIAVYDETGLV 65

Query: 289 EAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDP 468
             ++ N   Y N++  VV E+L +      + ++  D++  HR+       R P   +  
Sbjct: 66  GRIEGNAMSYINLLYTVVDEILLEGG-DVPMGEEPEDIFFYHRV--SRLKERFPE--KSA 120

Query: 469 RNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATY 648
              +P  L+RR+ +  K    S+   +R +K+ HIG L  V G+VT+ + VKP + VATY
Sbjct: 121 LEVFPSFLLRRYSLVLKPRRNSRVYSVRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATY 180

Query: 649 SC 654
            C
Sbjct: 181 VC 182


>UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7p;
           n=2; Cryptosporidium|Rep: Minichromosome maintenance
           protein mcm7p - Cryptosporidium hominis
          Length = 857

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 48/169 (28%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
 Frame = +1

Query: 163 QTDDEGK--KYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSD 336
           +T+ EG   K+ KY + L  +++RE+    +++DD+    +      +     Y N+V  
Sbjct: 50  ETEKEGSIWKHKKYMKSLQSISNREKNVLYIEVDDILSFGK-----YENKVTEYNNLVHS 104

Query: 337 VVYEMLPDYKFKEVVAKDSLDVYIEHRIM---LEARNHRIPGEMRDPRNRYPPELIRRFE 507
           ++       +   + A + L V     I+   LE  N+    E     N  P  L   FE
Sbjct: 105 ILSNTKRYVQLIYIAADNCLPVPTRTNIIDFKLEEMNNTKRSESMKTCN-VPAYLRSNFE 163

Query: 508 VYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           VY K        P+REV+AE++G    V  IVTR ++VKP + V  Y+C
Sbjct: 164 VYIKASKRMPITPLREVRAEYVGGYVQVNCIVTRVSNVKPRMQVVNYTC 212


>UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47
           homolog) (Minichromosome maintenance (MCM) complex
           subunit, putative); n=6; Trypanosomatidae|Rep: DNA
           replication licensing factor (CDC47 homolog)
           (Minichromosome maintenance (MCM) complex subunit,
           putative) - Leishmania major
          Length = 725

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 55/183 (30%), Positives = 86/183 (46%), Gaps = 2/183 (1%)
 Frame = +1

Query: 112 DYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNE-DLT 288
           +Y  D++  K F  +F   D  G+   KY  Q   +A R+ I F + LDD+    +  L 
Sbjct: 19  NYINDRDVCKRFLEEF--RDSTGQA--KYVIQAHHIAQRQSIVFSIFLDDVAGFGQLHLA 74

Query: 289 EAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDP 468
           + V+ N   Y   +  VV  ++P  +   VV  D +D     ++++EA   R+ G+    
Sbjct: 75  QRVQMNVVGYMEELYRVVDSIIP--QTDRVV--DMVD-----QLIMEA---RMSGQ---- 118

Query: 469 RNRYPPELIRRFEVYFKDLS-TSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVAT 645
               P  L RR+E+    LS  S  +P+RE+K   IG L  +RGI    T V+P L +  
Sbjct: 119 --ELPALLTRRYELKIHPLSEDSVPIPLRELKGGKIGTLTVLRGICIAATAVRPKLSMLV 176

Query: 646 YSC 654
             C
Sbjct: 177 SVC 179


>UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6;
           Thermoproteales|Rep: DNA replication licensing factor -
           Pyrobaculum aerophilum
          Length = 680

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 33/140 (23%), Positives = 71/140 (50%)
 Frame = +1

Query: 235 IAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEH 414
           ++ E++LD L +   +L  + ++ +    N++      +  D+    +  K   D+ +E 
Sbjct: 1   MSLEIELDLLRDKFRELVTSNEKISDEVINIIIQRKRSLEVDFHDILMFDKSLADLVVER 60

Query: 415 RIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVR 594
             ++     ++  E+ + ++    + ++RF  YF+   +  SV +R++++E+IG+L  + 
Sbjct: 61  PKLVLPEADKVVREIVEEKDPETAKALKRF--YFRVRGSPLSVSLRKLRSEYIGRLIKIE 118

Query: 595 GIVTRCTDVKPLLVVATYSC 654
           GIVTR T  K  L  A Y C
Sbjct: 119 GIVTRQTPPKHFLYKALYRC 138


>UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/3/5
           family; n=3; Thermococcus kodakarensis KOD1|Rep: DNA
           replication licensing factor, MCM2/3/5 family -
           Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
          Length = 1157

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/61 (39%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
 Frame = +1

Query: 475 RYPPELIRR-FEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYS 651
           R PP L+ R F+V+ +  +  K++ ++E+ +EHI KL  V GI+TR ++VKP +  A + 
Sbjct: 80  REPPLLVEREFKVHARFYNLPKTLLVKELGSEHINKLIQVEGIITRVSEVKPFVEKAVFV 139

Query: 652 C 654
           C
Sbjct: 140 C 140


>UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mcm
           protein - Archaeoglobus fulgidus
          Length = 698

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 21/47 (44%), Positives = 32/47 (68%)
 Frame = +1

Query: 514 FKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           F  L T++ V IR ++AEHIGK   + GIV + T+V+P +V A ++C
Sbjct: 90  FYSLPTARKVLIRNLRAEHIGKFMAIEGIVRKVTEVRPRIVEAAFAC 136


>UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;
           n=4; Sulfolobaceae|Rep: Minichromosome maintenance
           protein MCM - Sulfolobus solfataricus
          Length = 686

 Score = 36.3 bits (80), Expect(2) = 2e-04
 Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
 Frame = +1

Query: 445 IPGEMRDPRNRYPPELIRRFE-VYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDV 621
           + G + D   +  P   R  E V+ + +   + + +R++++  IGKL T+ GI+ + T V
Sbjct: 74  LEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPV 133

Query: 622 KPLLVVATY 648
           K  +  ATY
Sbjct: 134 KERIYKATY 142



 Score = 31.1 bits (67), Expect(2) = 2e-04
 Identities = 13/71 (18%), Positives = 34/71 (47%)
 Frame = +1

Query: 136 FKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRR 315
           +++ F++F  T        KY E++ ++    + +  ++  D+   NE+L   +  NT+ 
Sbjct: 10  YRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKI 69

Query: 316 YTNMVSDVVYE 348
              ++   +Y+
Sbjct: 70  ILPILEGALYD 80


>UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;
           n=2; Theileria|Rep: Replication licensing factor,
           putative - Theileria annulata
          Length = 1021

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/77 (37%), Positives = 42/77 (54%)
 Frame = +1

Query: 424 LEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIV 603
           LE     +  E+ +  NR P    R+F + F    T    P+REVK   +G+L  +RG V
Sbjct: 154 LEDVLQNLVNEISNAVNRVP----RKFYLQFLHTPTI-IYPLREVKCFMLGELICIRGQV 208

Query: 604 TRCTDVKPLLVVATYSC 654
           TR +DV+P L+ AT+ C
Sbjct: 209 TRVSDVRPELIRATFRC 225


>UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase,
           minichromosome maintenance protein; n=2; Pyrococcus|Rep:
           MCM inteins containing helicase, minichromosome
           maintenance protein - Pyrococcus abyssi
          Length = 1112

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 18/40 (45%), Positives = 28/40 (70%)
 Frame = +1

Query: 535 KSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           K++ ++E+ AEHI KL  V G+VTR T++KP +  A + C
Sbjct: 100 KTLMVKEIGAEHINKLIQVEGVVTRVTEIKPFVSSAVFVC 139


>UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Rep:
           Mcm protein - Methanosarcina acetivorans
          Length = 702

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 15/50 (30%), Positives = 33/50 (66%)
 Frame = +1

Query: 505 EVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           + + + ++    VPI E++++H+GKL ++ G+V + T+V+P +  A + C
Sbjct: 84  DAHVRIMNVPTRVPIGELRSKHLGKLISIEGMVRKATEVRPRITKAAFQC 133


>UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
           thermophila SB210|Rep: MCM2/3/5 family protein -
           Tetrahymena thermophila SB210
          Length = 826

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 20/47 (42%), Positives = 32/47 (68%)
 Frame = +1

Query: 514 FKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           F +L T K   IRE+  + IGKL +++G+VTR ++V+P L+  T+ C
Sbjct: 111 FYNLPTEKK--IRELGTQEIGKLNSIKGLVTRSSEVRPELLYGTFIC 155


>UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1;
           Pyrococcus furiosus|Rep: Cell division control protein
           21 - Pyrococcus furiosus
          Length = 1049

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 17/50 (34%), Positives = 33/50 (66%)
 Frame = +1

Query: 505 EVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +++ +  +  +++ ++++ AEHI KL  V GIVTR  ++KP + VA + C
Sbjct: 90  KIHARFYNLPETLMVKDIGAEHINKLIQVEGIVTRVGEIKPFVSVAVFVC 139


>UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: MCM family protein -
           Halorubrum lacusprofundi ATCC 49239
          Length = 700

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
 Frame = +1

Query: 274 NEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPG 453
           N+DLTE   Q  R Y       + +  P+ +    +  D  D+Y   R + E    + P 
Sbjct: 6   NQDLTERFIQFYRNYYREEIGGLAQRYPNEQRSLYIEYD--DLYQFDRDLAEDFRTK-PE 62

Query: 454 EMRDPRNRYPPELIRRFEV---------YFKDLSTSKSVPIREVKA--EHIGKLXTVRGI 600
           +MR+    Y  E +R +++         + +  +  +S+ IR ++   +HIGKL +++GI
Sbjct: 63  QMRE----YAEEALRLYDLPADVSLGRAHVRIENLPESIDIRGIRVHDDHIGKLVSIKGI 118

Query: 601 VTRCTDVKPLLVVATYSC 654
           V + TDV+P +  A + C
Sbjct: 119 VRKATDVRPKVTEAAFEC 136


>UniRef50_P53091 Cluster: DNA replication licensing factor MCM6;
           n=7; Saccharomycetales|Rep: DNA replication licensing
           factor MCM6 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 1017

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 21/58 (36%), Positives = 37/58 (63%)
 Frame = +1

Query: 481 PPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           P +  R F++ F +L T     IR++++E IG L ++ G VTR ++V+P L  A+++C
Sbjct: 256 PEQTERVFQISFFNLPTVHR--IRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTC 311


>UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
           vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
           vaginalis G3
          Length = 754

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 42/177 (23%), Positives = 72/177 (40%), Gaps = 1/177 (0%)
 Frame = +1

Query: 127 KESFKNFFVDFCQT-DDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQ 303
           +   K  F+ F  T  +EG     Y  Q  K+   E     V  + L++ +    E + +
Sbjct: 8   QNQIKARFLTFLNTYKEEGSDELYYHVQFEKMKEEENTTLRVSYEHLYQFDSTFAEIIAE 67

Query: 304 NTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYP 483
           N  R+ N +       L D+    V+A+D +              + I G   +PR    
Sbjct: 68  NLYRFYNSL----VAALVDF----VMAQDKM--------------YAIEGRTHNPRP--- 102

Query: 484 PELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
                 F +   D +   +  +R++K  H+G L   +G VTR +DV+P L+  T+ C
Sbjct: 103 ------FALSITDYNVKSA--LRQIKPSHVGTLIMFQGTVTRISDVQPELLKGTFRC 151


>UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1;
           Haloarcula marismortui|Rep: Cell division control
           protein 21 - Haloarcula marismortui (Halobacterium
           marismortui)
          Length = 1175

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +1

Query: 535 KSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +S  IR+++ EH G L  VRGI+ + TDV+P ++ A + C
Sbjct: 95  ESEDIRDLRHEHHGNLVAVRGIIRKATDVRPKVIEAAFEC 134


>UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n=1;
           Babesia bovis|Rep: ATP dependent DNA helicase, putative
           - Babesia bovis
          Length = 765

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 9/163 (5%)
 Frame = +1

Query: 193 KYAEQLTKVAHREQIAFEVDLDD-----LHEMNE-DLTEAVKQNTRRYTNMV---SDVVY 345
           +Y  QL ++ +R+     V LDD     L + NE  + E +  N  RY  ++   +D   
Sbjct: 49  RYMNQLQEIKNRKSNILRVYLDDIRQHFLKDTNEHQVYEGLMLNAYRYLELMYAAADACL 108

Query: 346 EMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDL 525
           E +     +    + S   + ++  +L++ +     E R  +++ P  L   FE++    
Sbjct: 109 EGIERNVEEHDPYRLSPGRHNQNPDVLDSVDEL--RERRMKQSKLPVYLYSNFEIWLIPG 166

Query: 526 STSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           S+   + ++ V A++IG L  +   VTR   +KP + VATY C
Sbjct: 167 SSDSVMKMKTVNADYIGCLSLIEVDVTRVGLLKPRVQVATYEC 209


>UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM
           related protein; n=1; uncultured euryarchaeote
           Alv-FOS1|Rep: DNA replication licensing factor MCM
           related protein - uncultured euryarchaeote Alv-FOS1
          Length = 682

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 15/44 (34%), Positives = 28/44 (63%)
 Frame = +1

Query: 523 LSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +S +  + IR+++  HIGK   +RGI+ R ++V+P L +  + C
Sbjct: 88  ISDNFKMEIRKLRTTHIGKFVAIRGIIRRASEVRPKLKIGAFKC 131


>UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=9;
           Magnoliophyta|Rep: Uncharacterized protein At5g44635.1 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 831

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 29/96 (30%), Positives = 45/96 (46%)
 Frame = +1

Query: 367 FKEVVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVP 546
           F + + K   D Y+     L     R   EM +P         +   V F +L  +K   
Sbjct: 63  FNDALQKAIADEYLRFEPYLRNACKRFVIEM-NPSFISDDTPNKDINVSFYNLPFTKR-- 119

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +RE+    IGKL +V G+VTR ++V+P L+  T+ C
Sbjct: 120 LRELTTAEIGKLVSVTGVVTRTSEVRPELLYGTFKC 155


>UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium
           discoideum|Rep: MCM family protein - Dictyostelium
           discoideum AX4
          Length = 867

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 17/43 (39%), Positives = 29/43 (67%)
 Frame = +1

Query: 526 STSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           + S  V IRE+++  IG L ++ G VTR ++V+P LV+ ++ C
Sbjct: 164 NVSTFVHIRELRSSRIGSLCSISGTVTRTSEVRPELVIGSFIC 206


>UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_45,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 803

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 34/139 (24%), Positives = 68/139 (48%), Gaps = 2/139 (1%)
 Frame = +1

Query: 244 EVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSL--DVYIEHR 417
           E  +  L+++NE   + +     R+    ++ +Y+ L  Y  + +   D++   V+ +  
Sbjct: 94  EYYMSQLNQLNET-DQFILNIDGRHLLEFNNHLYQQLIHYPAEIIPIFDTVVQKVFYDDF 152

Query: 418 IMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRG 597
           + L+ARN +   E R     Y   L+         ++  ++V +RE+  + I KL +V G
Sbjct: 153 LSLKARNEQEREEFR----LYAQRLLIGI------INLERNVQVRELNPKDINKLISVTG 202

Query: 598 IVTRCTDVKPLLVVATYSC 654
           IV RC+++ P +  AT+ C
Sbjct: 203 IVIRCSELYPDMKQATFKC 221


>UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermus
           marinus F1|Rep: MCM family protein - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 1047

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 28/75 (37%), Positives = 41/75 (54%)
 Frame = +1

Query: 424 LEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIV 603
           +EA +  I   MR     Y  E + +F   F++   SK + IRE+ +E+IGK   V GI+
Sbjct: 76  IEAASIAIKELMRRENPEYA-ESVDKFYPRFRN--PSKVLRIRELTSEYIGKFVAVEGIL 132

Query: 604 TRCTDVKPLLVVATY 648
           TR T V+  LV A +
Sbjct: 133 TRLTRVEARLVKAVF 147


>UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-like
           AAA ATpase; n=3; Cryptosporidium|Rep: DNA replication
           licensing factor MCM6-like AAA ATpase - Cryptosporidium
           parvum Iowa II
          Length = 1055

 Score = 39.9 bits (89), Expect = 0.052
 Identities = 15/36 (41%), Positives = 26/36 (72%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R ++ E +GKL ++RG +TR +DV+P L+ A + C
Sbjct: 147 LRTLRCEKLGKLCSLRGTITRTSDVRPELIKACFEC 182


>UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7
           homolog), putative; n=2; Theileria|Rep: DNA replication
           licensing factor (MCM7 homolog), putative - Theileria
           annulata
          Length = 827

 Score = 39.9 bits (89), Expect = 0.052
 Identities = 43/192 (22%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
 Frame = +1

Query: 121 ADKESFKNFFVDFC-----QTDDEGKKYF---KYAEQLTKVAHREQIAFEVDLDDLHEM- 273
           A  +S   FF +F      Q +D   K F   KY  QL  + +      +V +DD+ +  
Sbjct: 17  AHTKSLSTFFEEFTSPLNLQDEDGDYKPFGDKKYKNQLQMIKNDSSKVLKVYMDDVRQYF 76

Query: 274 -----NEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARN 438
                ++D  E +  NT RY  ++  +  EM+      E + KD  + Y +  +  +  +
Sbjct: 77  LKENHDKDFYEGLMMNTYRYLELLY-IASEMV-----LEKLTKD--ENYPKFGLYYDPID 128

Query: 439 HRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTD 618
                 M+  +N+ P  L   +++   + +    + ++ V A+ +G L  +   V +  +
Sbjct: 129 ELRVSRMK--QNKLPINLRSNYDILLVNGNDDYIMKMKYVNADFVGCLVLIEVDVFKVAN 186

Query: 619 VKPLLVVATYSC 654
           + P L++ATY C
Sbjct: 187 ISPKLLIATYEC 198


>UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep:
           NEQ282 - Nanoarchaeum equitans
          Length = 657

 Score = 39.9 bits (89), Expect = 0.052
 Identities = 18/53 (33%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
 Frame = +1

Query: 502 FEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLL--VVATYSC 654
           + + F D+   ++V IRE+++ H+ KL  + GI+ + + VKP+L   V  +SC
Sbjct: 72  YYIAFTDVQYYRNVKIRELRSHHLNKLVAIEGIIKQSSMVKPVLKRAVFRHSC 124


>UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1;
           Natronomonas pharaonis DSM 2160|Rep: ATP-dependent DNA
           helicase - Natronomonas pharaonis (strain DSM 2160 /
           ATCC 35678)
          Length = 1037

 Score = 39.9 bits (89), Expect = 0.052
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IR+++A H G L  V GIV + TDV+P +  A + C
Sbjct: 99  IRDIRARHRGNLVEVTGIVRKATDVRPKITEAAFEC 134


>UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance
           protein; n=3; Methanobacteriaceae|Rep: Predicted
           minichromosome maintenance protein - Methanosphaera
           stadtmanae (strain DSM 3091)
          Length = 670

 Score = 39.9 bits (89), Expect = 0.052
 Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
 Frame = +1

Query: 340 VYEMLPDYKFKEVVAKDSLDVYIEHR--IMLEARNHRIPGEMRDPRNRYPPELIRRFEVY 513
           V +M P+ K   VV  + L+++      +++E  +  +    +   N  P     +  V 
Sbjct: 34  VLDMFPEEK-SVVVDYNELEMFDPDSADLLIEKPDETLEAATKSIVNIDPQRKNAKLNVR 92

Query: 514 FKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           FK++  +  +P+R +++E IGK   V GIV +  ++ P ++ A + C
Sbjct: 93  FKNVRNN--IPLRFLRSEFIGKFIAVDGIVRKTDEIHPRIMSAVFEC 137


>UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1;
           Haloquadratum walsbyi DSM 16790|Rep: ATP-dependent DNA
           helicase - Haloquadratum walsbyi (strain DSM 16790)
          Length = 2216

 Score = 39.5 bits (88), Expect = 0.069
 Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 7/133 (5%)
 Frame = +1

Query: 277 EDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGE 456
           +DLT+   Q  R+Y       + +  P  K    +  D  D+Y    + L     R P +
Sbjct: 9   QDLTDRFIQFYRKYYRDDIGTLAQQFPHEKRSLYI--DYHDLYA-FDVELAEDYRREPDQ 65

Query: 457 MRDPRNR----YP-PELIRRFEVYFKDLSTSKSVPIREVKA--EHIGKLXTVRGIVTRCT 615
           +R+        Y  P  ++    + +  S   +V IR ++   +HIG L  V+GIV + T
Sbjct: 66  LREYAEEALRLYDLPADVKLGRAHVRMRSLPDTVDIRNIRVHDDHIGHLIAVQGIVRKAT 125

Query: 616 DVKPLLVVATYSC 654
           DV+P +  A + C
Sbjct: 126 DVRPKITEAAFEC 138


>UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta
           thermophila PT|Rep: MCM family protein - Methanosaeta
           thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 689

 Score = 39.5 bits (88), Expect = 0.069
 Identities = 15/35 (42%), Positives = 24/35 (68%)
 Frame = +1

Query: 550 REVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           R+++++HIGKL  + G V   T+V+P +V A Y C
Sbjct: 95  RDLRSDHIGKLIAIEGQVRTATEVRPKIVRAAYEC 129


>UniRef50_Q22D74 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2107

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 28/109 (25%), Positives = 56/109 (51%), Gaps = 1/109 (0%)
 Frame = +1

Query: 199  AEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLP-DYKFKE 375
            A+QL + +  +    E +   LH++++ L E  +Q   +Y N VSDV Y +   + + +E
Sbjct: 1882 ADQLQRSSRHQSDQEEYERRSLHQLDQ-LEEEDQQRDNQYLNQVSDVQYTLQEMESRIQE 1940

Query: 376  VVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKD 522
            ++A+D  +   +H+ +LE   +   GE  +  +   P+L  R  + + D
Sbjct: 1941 LMARDE-EAQRQHQQILEDEQNYDHGEYNNNYSD-QPQLSLRIRLQYAD 1987


>UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6,
           putative; n=7; Plasmodium|Rep: DNA replication licensing
           factor MCM6, putative - Plasmodium vivax
          Length = 944

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 15/36 (41%), Positives = 26/36 (72%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R ++ E +G++ +VRG VTR +DV+P L +A + C
Sbjct: 221 LRSLRCEMLGEMISVRGQVTRTSDVRPELTLAAFKC 256


>UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 877

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 15/36 (41%), Positives = 28/36 (77%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R ++A++IG+L ++ G VTR ++V+P L +AT+ C
Sbjct: 392 VRALRAKNIGQLLSISGTVTRTSEVRPELSLATFMC 427


>UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489;
           n=10; Methanococcales|Rep: Uncharacterized MCM-type
           protein MJ1489 - Methanococcus jannaschii
          Length = 682

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
 Frame = +1

Query: 469 RNRYPPELI---RRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVV 639
           RN YP  +I   +     FK     K   I +++++ +GKL    GI+   + ++P+L  
Sbjct: 87  RNEYPTNVIIAVKNLPKIFKTTRKGKIFTIEDIRSKTLGKLVEFEGIIVMASKIRPMLKK 146

Query: 640 ATYSC 654
           A Y C
Sbjct: 147 AYYIC 151


>UniRef50_P49731 Cluster: DNA replication licensing factor mcm6;
           n=4; Dikarya|Rep: DNA replication licensing factor mcm6
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 892

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 15/36 (41%), Positives = 25/36 (69%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IR+++ + IG+L T+ G VTR ++V+P L   T+ C
Sbjct: 198 IRDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFIC 233


>UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3
           homolog; n=15; Magnoliophyta|Rep: DNA replication
           licensing factor MCM3 homolog - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 776

 Score = 39.1 bits (87), Expect = 0.091
 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
 Frame = +1

Query: 463 DPRNRYPPELIR-RFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVV 639
           DP+     EL+   FE YF     S+ V  RE+ ++ IG +  V GIVT+C+ V+P +V 
Sbjct: 79  DPKYLKEGELVLVGFEGYF----VSRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVK 134

Query: 640 ATYSC 654
           + + C
Sbjct: 135 SVHFC 139


>UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole genome
           shotgun sequence; n=3; Magnoliophyta|Rep: Chromosome
           chr8 scaffold_29, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 741

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 15/38 (39%), Positives = 27/38 (71%)
 Frame = +1

Query: 541 VPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           + ++ +K+ +I KL +VRG V + + VKPL+V  T++C
Sbjct: 129 IALKNLKSAYIDKLVSVRGTVVKASTVKPLVVQMTFAC 166


>UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
           MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA
           REPLICATION LICENSING FACTOR OF THE MCM FAMILY -
           Encephalitozoon cuniculi
          Length = 726

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 17/36 (47%), Positives = 24/36 (66%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IRE+K+  +G+L +  G VTR T V+P LV  T+ C
Sbjct: 112 IRELKSNRLGQLLSFSGTVTRTTQVRPELVSGTFVC 147


>UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6
           component; n=4; Saccharomycetaceae|Rep: DNA replication
           licensing factor, MCM6 component - Pichia stipitis
           (Yeast)
          Length = 949

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 19/53 (35%), Positives = 33/53 (62%)
 Frame = +1

Query: 496 RRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           R F++ F +L T     IR+++   IG L ++ G VTR ++V+P L  A+++C
Sbjct: 209 RVFQISFFNLPTINR--IRDIRTAKIGSLMSISGTVTRTSEVRPELFRASFTC 259


>UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing factor
           ATPase; n=2; Thermoprotei|Rep: Cdc46/Mcm DNA replication
           licensing factor ATPase - Cenarchaeum symbiosum
          Length = 697

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 16/36 (44%), Positives = 24/36 (66%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +RE+ A+ I K+ +V G+V R ++VKPL     YSC
Sbjct: 111 LREINADIINKMTSVSGMVVRASEVKPLAKELVYSC 146


>UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 755

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 16/37 (43%), Positives = 24/37 (64%)
 Frame = +1

Query: 544 PIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           P+R++    I K+  VRG+VTRCT + P L +A + C
Sbjct: 137 PMRDLNPSDIDKMVCVRGMVTRCTTIIPDLKLAYFKC 173


>UniRef50_UPI000049A27A Cluster: DNA replication licensing factor;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
           replication licensing factor - Entamoeba histolytica
           HM-1:IMSS
          Length = 733

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           I+E+KA  IGKL  ++G V R + +KP LV   + C
Sbjct: 119 IKELKASSIGKLICIKGTVIRASSIKPHLVSMVFCC 154


>UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_680_44640_47504 - Giardia lamblia
           ATCC 50803
          Length = 954

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 15/36 (41%), Positives = 25/36 (69%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           + E+ + HIG+L  + G VTR +DV+P L++ T+ C
Sbjct: 139 LSELTSSHIGQLVELVGTVTRTSDVQPELILGTFRC 174


>UniRef50_Q4Q826 Cluster: DNA replication licensing factor,
           putative; n=6; Trypanosomatidae|Rep: DNA replication
           licensing factor, putative - Leishmania major
          Length = 880

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 14/40 (35%), Positives = 27/40 (67%)
 Frame = +1

Query: 535 KSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           + + IR ++A  +G+L  ++G+VTR + V+P L+V  + C
Sbjct: 153 RCLTIRSLRASLVGQLCAIKGVVTRTSQVRPELLVGVFRC 192


>UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2;
           Desulfurococcales|Rep: Minichromosome maintenance
           protein - Aeropyrum pernix
          Length = 697

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 21/75 (28%), Positives = 40/75 (53%)
 Frame = +1

Query: 130 ESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNT 309
           E FK F  +F    +EGK   KY E + ++ + E+ + EV+  DL+  +  L+E + +  
Sbjct: 16  ERFKTFLENF--RTEEGK--LKYVEAIRRMINYEETSLEVEFKDLYRYDPLLSEILLEKP 71

Query: 310 RRYTNMVSDVVYEML 354
           R +    S+ + E++
Sbjct: 72  REFLKEASEALKEIV 86


>UniRef50_Q979U9 Cluster: DNA replication initiator; n=4;
           Thermoplasmatales|Rep: DNA replication initiator -
           Thermoplasma volcanium
          Length = 699

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
 Frame = +1

Query: 496 RRFEVYFKDLST-SKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           R F +  KDL   + S  IR++++ +IG L +V GIV + T+V P L  A + C
Sbjct: 88  RIFHLRIKDLEDRNTSYNIRDIRSANIGTLISVSGIVRKNTEVFPKLKNAAFEC 141


>UniRef50_P30666 Cluster: DNA replication licensing factor mcm3;
           n=10; Fungi/Metazoa group|Rep: DNA replication licensing
           factor mcm3 - Schizosaccharomyces pombe (Fission yeast)
          Length = 879

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 17/51 (33%), Positives = 30/51 (58%)
 Frame = +1

Query: 502 FEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           F V F+       V  R ++A H+ K+ ++ GIVTRC+ V+P ++ + + C
Sbjct: 102 FYVGFRGSFGDHHVNPRTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYC 152


>UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM6;
           n=2; Ostreococcus|Rep: Mini-chromosome maintenance
           protein MCM6 - Ostreococcus tauri
          Length = 873

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 17/56 (30%), Positives = 33/56 (58%)
 Frame = +1

Query: 487 ELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           E  R  E + K ++  +   +R ++A +IG+L +  G VTR ++V+P L++  + C
Sbjct: 122 EKSREKEFWVKFVNLPRVERLRSLRANNIGQLSSFSGTVTRTSEVRPELLLGCFKC 177


>UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_29_20689_22803 - Giardia lamblia
           ATCC 50803
          Length = 704

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
 Frame = +1

Query: 445 IPGEMRDPRNRYPPELIRRF--EVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTD 618
           +P E R      P  L R F  E+  ++      +P+R V A  IG L    GIVT  + 
Sbjct: 82  LPEEERGQYTNQPYRLSRWFSVEIVPENDMLEHPLPLRSVSASMIGHLVVFSGIVTFISQ 141

Query: 619 VKPLLVVATYSC 654
           V P   +AT++C
Sbjct: 142 VVPECEIATFTC 153


>UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
           vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
           vaginalis G3
          Length = 842

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 20/62 (32%), Positives = 31/62 (50%)
 Frame = +1

Query: 469 RNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATY 648
           R  YP   IR+  V    L    +  IR+++  H+  L   +G+VTRC D+ P L+   +
Sbjct: 229 RKMYPNLDIRKITVRITHLPIIDN--IRDLRQIHLDSLVRTKGVVTRCNDILPHLLQIKW 286

Query: 649 SC 654
            C
Sbjct: 287 RC 288


>UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 921

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 19/53 (35%), Positives = 31/53 (58%)
 Frame = +1

Query: 496 RRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           R F++ F +L       IRE+K + IG L ++ G VTR ++V+P L +  + C
Sbjct: 209 RHFQICFHNLPVV--CRIRELKTDKIGCLISLGGTVTRTSEVRPELYLGAFQC 259


>UniRef50_Q5HCB0 Cluster: Putative uncharacterized protein Erum0660;
            n=3; Ehrlichia ruminantium|Rep: Putative uncharacterized
            protein Erum0660 - Ehrlichia ruminantium (strain
            Welgevonden)
          Length = 3715

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 22/70 (31%), Positives = 37/70 (52%)
 Frame = +2

Query: 146  FSWIFVKLMMKEKSILNMLNNLLKLHTENR*HLKLTWMIYMR*MKI*LRQSNKIPEDTLI 325
            F WI   +  K   I+N+++  +  + E   H+KL  MI     ++ +RQS K+P    +
Sbjct: 1119 FVWILKNI--KPSEIINVIDENIAEYRETNDHMKLYDMI-----EVSIRQSYKVPNLPSM 1171

Query: 326  WCQTWFMKCC 355
            +  T F+KCC
Sbjct: 1172 FTDTQFIKCC 1181


>UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7;
           n=8; Plasmodium|Rep: DNA replication licensing factor
           mcm7 - Plasmodium yoelii yoelii
          Length = 850

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 24/67 (35%), Positives = 30/67 (44%)
 Frame = +1

Query: 454 EMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLL 633
           E R    + P  L   FE+     S      +R V A+ IG L T    V R T +KP +
Sbjct: 201 EERMKEYKLPAYLRVNFEIILIPSSRDLIRKMRIVNADCIGSLSTFECEVIRATQLKPRI 260

Query: 634 VVATYSC 654
            VATY C
Sbjct: 261 QVATYEC 267


>UniRef50_A7S8B1 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 191

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
 Frame = +1

Query: 172 DEGKKYFKYA---EQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVV 342
           D+ ++Y KY    E+L     REQ +F+  ++DL    ++  EAV++++  +T    DV 
Sbjct: 45  DQEQRYLKYMSNLEELQNEEKREQESFKSQIEDLKTRCQEKQEAVEKSSADFTKFKFDVA 104

Query: 343 YEMLPDYKFKEVVAKD 390
            + +     K +  KD
Sbjct: 105 KQAINSRSGKPIPPKD 120


>UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2;
           n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION
           LICENSING FACTOR MCM2 - Encephalitozoon cuniculi
          Length = 780

 Score = 37.1 bits (82), Expect = 0.37
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R ++  H+GKL  V G+VTR + V PL  +  +SC
Sbjct: 202 VRSLRNRHLGKLVRVSGVVTRRSGVFPLYSIVKFSC 237


>UniRef50_UPI00006CFD9E Cluster: conserved hypothetical protein; n=1;
            Tetrahymena thermophila SB210|Rep: conserved hypothetical
            protein - Tetrahymena thermophila SB210
          Length = 2254

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = +1

Query: 166  TDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRY--TNMVSDV 339
            TD + K YF   EQ++K+ H+ Q   +  + ++   N +L E VK     Y  T M++D+
Sbjct: 963  TDSDIKDYFNKFEQISKITHQNQKEIQ-KIKEVIFQNNNLIELVKLPVNLYLTTRMLNDL 1021

Query: 340  VYEMLPDYKFKEV-VAKDSLDV 402
              ++  D  FK++  A D +D+
Sbjct: 1022 --DLKDDKIFKDLKQASDQVDI 1041


>UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14;
           Ascomycota|Rep: DNA replication licensing factor -
           Aspergillus oryzae
          Length = 970

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 13/36 (36%), Positives = 25/36 (69%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R+++   IGKL ++ G VTR ++++P L + T+ C
Sbjct: 239 LRQLRTSQIGKLLSISGTVTRTSEIRPELSLGTFIC 274


>UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia
           bovis|Rep: MCM2/3/5 family protein - Babesia bovis
          Length = 918

 Score = 36.3 bits (80), Expect = 0.64
 Identities = 13/36 (36%), Positives = 25/36 (69%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +++++   +G+L T+ G VTR +DV+P L+  T+ C
Sbjct: 193 LKDLRCHMLGELLTISGQVTRTSDVRPELIRGTFKC 228


>UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus
           tropicalis|Rep: MGC146393 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 675

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = +1

Query: 544 PIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           P++ ++A   GK   +RG V R +++KPL V   +SC
Sbjct: 197 PLKNLRASLYGKYVALRGTVVRVSNIKPLCVKMAFSC 233


>UniRef50_Q8ILG6 Cluster: Coatamer protein, beta subunit, putative;
           n=3; Plasmodium|Rep: Coatamer protein, beta subunit,
           putative - Plasmodium falciparum (isolate 3D7)
          Length = 1394

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 15/50 (30%), Positives = 26/50 (52%)
 Frame = +2

Query: 62  EDSNYSNNIFLTKWQCVITLQIKNLSRTFSWIFVKLMMKEKSILNMLNNL 211
           +++N+ NNI       +  ++   + R F W+  + M  E  I+N LNNL
Sbjct: 645 KNNNFQNNILEKMIDSIFDIKKATILRIFFWVIGQYMFNEHMIINFLNNL 694


>UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 like
           AAA+ ATpase; n=2; Cryptosporidium|Rep: DNA replication
           licensing factor MCM4 like AAA+ ATpase - Cryptosporidium
           parvum Iowa II
          Length = 896

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +REV    I +L ++RGIV RC+D+ P +  A + C
Sbjct: 230 MREVNPSDIEQLVSIRGIVIRCSDIIPEMQKAVFRC 265


>UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_99,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 805

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
 Frame = +1

Query: 505 EVYFKDLST-SKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           ++YF  +S  + +  IR+++A  IGKL +  G VTR  +V+P L+   ++C
Sbjct: 102 KLYFLAVSNLAATEKIRDLRANKIGKLSSFIGTVTRTYEVRPELLSGQFTC 152


>UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;
           n=1; Halobacterium salinarum|Rep: MCM / cell division
           control protein 21 - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 831

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 13/36 (36%), Positives = 24/36 (66%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IR ++AEH+  + +++G+V + TDV P +  A + C
Sbjct: 51  IRAIRAEHLNTMVSIQGMVRKATDVMPKIQRAVFVC 86


>UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing factor;
           n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
           DNA replication licensing factor - Uncultured
           methanogenic archaeon RC-I
          Length = 862

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 12/44 (27%), Positives = 26/44 (59%)
 Frame = +1

Query: 523 LSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +   +   +RE+++  + KL ++ G V + TDV+P ++ A + C
Sbjct: 88  IKVPRKTQVRELRSSDVNKLVSLEGTVRKITDVRPRILEAAFEC 131


>UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/3/5
           family; n=1; Thermococcus kodakarensis KOD1|Rep: DNA
           replication licensing factor, MCM2/3/5 family -
           Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
          Length = 810

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/56 (33%), Positives = 33/56 (58%)
 Frame = +1

Query: 487 ELIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           E+   + V+F +L   K  P  +V+AEH+GKL  ++G+VT  ++V+     A + C
Sbjct: 228 EVRGEWSVHFTNLR-DKLKP-EDVRAEHVGKLVEIKGLVTGVSNVRSFYRKAVFVC 281


>UniRef50_UPI0000499A20 Cluster: hypothetical protein 53.t00045;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 53.t00045 - Entamoeba histolytica HM-1:IMSS
          Length = 511

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 16/75 (21%), Positives = 38/75 (50%)
 Frame = +1

Query: 169 DDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYE 348
           +D+ +K      ++  + ++E+I    ++  + EM   + E  K+N +   NM     Y 
Sbjct: 262 NDKQEKIESVLNEIKTICYKERIVMNKEISSIEEMEISIEEQNKENEQMVENMKGLEDYF 321

Query: 349 MLPDYKFKEVVAKDS 393
           +    +FK+++A++S
Sbjct: 322 VQQTNEFKKIIAEES 336


>UniRef50_A3DIH5 Cluster: Radical SAM; n=1; Clostridium thermocellum
           ATCC 27405|Rep: Radical SAM - Clostridium thermocellum
           (strain ATCC 27405 / DSM 1237)
          Length = 341

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 21/95 (22%), Positives = 43/95 (45%)
 Frame = +1

Query: 208 LTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAK 387
           ++K  ++E    E+D D+ +  N     ++K NT+ Y   +   +     + KF  +   
Sbjct: 149 VSKERYKETCGVEIDFDE-YVKNLSYLYSIKGNTQIYIKAIDATLKSKEEEEKFFNIFGN 207

Query: 388 DSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPEL 492
               +YIEH I+++ +   +   +   +N Y  EL
Sbjct: 208 ICDKIYIEHLIVMQQQMGELKKIVDGTKNFYNEEL 242


>UniRef50_A0YYA0 Cluster: Putative uncharacterized protein; n=2;
           Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
           protein - Lyngbya sp. PCC 8106
          Length = 873

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 21/110 (19%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
 Frame = +1

Query: 202 EQLTKVAHRE-QIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEV 378
           E+L KV  +E ++  +  L+  H+  ED+ + +    R++   + +   E+    K+KE 
Sbjct: 214 EKLEKVLPQEAEVKPQKQLESKHQQAEDIQQQISDLKRQHQEQLQNREAEL--SVKYKEQ 271

Query: 379 VAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLS 528
           + +   ++ ++H+  LE    ++  + ++   R   EL+ +     K ++
Sbjct: 272 IRQREAELSLQHQEQLEKSESQLKHQHQEQLKRRETELLAQINQLQKQIT 321


>UniRef50_Q54H83 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 726

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
 Frame = +1

Query: 118 TADKESFKNF--FVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTE 291
           T+D  S +NF  F+D   +D     YFK   +  K+  +E +   VD D  ++ N+  T 
Sbjct: 28  TSDMVSIENFEFFLDHVYSDVLSSYYFKTLIEQEKILKKEDLNKIVDGDKDND-NKQATR 86

Query: 292 AVK-QNTRRYTNMVSDVVYEMLPDYKFKE---VVAKDSLDVY 405
            +  Q+  +  +++  ++   + DYK K    V+  DS +V+
Sbjct: 87  IINTQDKDKRIDIIKQIMNSKIRDYKTKVDNFVLESDSFEVF 128


>UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
           vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
           vaginalis G3
          Length = 752

 Score = 34.7 bits (76), Expect = 2.0
 Identities = 18/50 (36%), Positives = 29/50 (58%)
 Frame = +1

Query: 505 EVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           EV  +  +  ++  IRE+    I +L +VRG++TR + V P L  AT+ C
Sbjct: 146 EVQVRPYNLLETKSIRELHPTDIDRLVSVRGMITRSSPVIPDLSQATFRC 195


>UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 915

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 13/34 (38%), Positives = 24/34 (70%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATY 648
           +R+++   IGKL +V G VTR ++++P L + T+
Sbjct: 242 LRQLRTSQIGKLLSVSGTVTRTSEIRPELSLGTF 275


>UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome
           shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 15
           SCAF14542, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 996

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 21/55 (38%), Positives = 27/55 (49%)
 Frame = +1

Query: 490 LIRRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           L + F V  +DL T     IRE+ +  IG L  + G V R   V P LV  T+ C
Sbjct: 103 LNKEFYVALEDLPTRHK--IRELSSMRIGTLVKISGQVVRTHPVHPELVSGTFQC 155


>UniRef50_Q5TN00 Cluster: ENSANGP00000028786; n=4; Culicidae|Rep:
           ENSANGP00000028786 - Anopheles gambiae str. PEST
          Length = 694

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
 Frame = +1

Query: 193 KYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFK 372
           K  ++  K+A  E +  E +  DL  + E   E +K+N  R   +   +  E+ P  K +
Sbjct: 432 KELDKCQKIAETEIMQCEFEKRDLRTLWEASNEVIKENENRLAELERRLKVELEPGAKSR 491

Query: 373 EVVAKDSLDVYIE-HRIMLEARNHRI 447
           + +  ++ D+ +E  R+  E  N+++
Sbjct: 492 DELETEARDLALECSRLKTEKYNYQL 517


>UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 231

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 14/47 (29%), Positives = 29/47 (61%)
 Frame = +1

Query: 496 RRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLV 636
           +++ + FK    S SV  R + + ++ K+ ++ GIVTR + V+P ++
Sbjct: 109 QQYYLSFKGAFGSHSVTARSIDSSYLSKMVSIEGIVTRASLVRPKVI 155


>UniRef50_P49736 Cluster: DNA replication licensing factor MCM2;
           n=45; Fungi/Metazoa group|Rep: DNA replication licensing
           factor MCM2 - Homo sapiens (Human)
          Length = 904

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R ++  H+ +L    G+VT CT V P L +  Y+C
Sbjct: 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNC 329


>UniRef50_Q6KD52 Cluster: Putative uncharacterized protein; n=4;
           Enterobacteriaceae|Rep: Putative uncharacterized protein
           - Escherichia coli
          Length = 186

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
 Frame = +1

Query: 196 YAEQLTKVAHR-EQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDYKFK 372
           Y +     A R E       L D H+ + +L EAV Q   +   M+ D++       +FK
Sbjct: 81  YLDAFAGCAERGEMCGIYAMLSDSHQFSPELQEAVSQLAHQEIQMIKDIITSGQNSGEFK 140

Query: 373 EVVAKDSLDVYI 408
            V+  D L V +
Sbjct: 141 TVLLPDELAVIV 152


>UniRef50_A7HCY8 Cluster: Heavy metal efflux pump, CzcA family; n=9;
           Bacteria|Rep: Heavy metal efflux pump, CzcA family -
           Anaeromyxobacter sp. Fw109-5
          Length = 1040

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
 Frame = +1

Query: 376 VVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTSKSVPIRE 555
           V A+D LDV       +EA   R+ GE+R+   R+ P  +R    Y +D     +VP+R 
Sbjct: 729 VAARDVLDV-------VEAVGTRVAGEVREGERRF-PLAVRLRAPYREDPEKLATVPVRT 780

Query: 556 VKAEHI--GKLXTVRGI 600
              + +  G+L T+R +
Sbjct: 781 PSGDRVPLGRLATIREV 797


>UniRef50_Q9VDT2 Cluster: CG17186-PA; n=1; Drosophila
           melanogaster|Rep: CG17186-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 381

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
 Frame = +1

Query: 175 EGKKYFKYAEQLTKVAHREQIAF--EVDLDDLHEMN--EDLTEAVKQNTRRYTNMVS-DV 339
           E  +Y +   +L ++ HRE+  F  E+D+D + E +  ED+ +  KQN     N+V  D 
Sbjct: 277 EPVEYLEAENELEEIDHREERNFVEELDMDVMEEPDVVEDIQDIDKQNGLEEINLVEIDE 336

Query: 340 VYEMLPDYKFKEVVAKDSLDVYIE 411
           V ++ P ++  E    +  +VY E
Sbjct: 337 VVQIDPGFEMIEYTTAEE-NVYEE 359


>UniRef50_A0DPP4 Cluster: Chromosome undetermined scaffold_59, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_59, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2949

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 3/107 (2%)
 Frame = +1

Query: 115  YTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQIAFE-VDLDDLHEMNEDLTE 291
            Y   KE+F+N  +DF Q   +   Y  +  QL KV  + ++  E ++ +   ++ + +  
Sbjct: 2051 YDGGKETFQNDCIDFIQHQIQSPVYDYFCSQL-KVMQKSELPMEYMESNKTCQIGKFI-- 2107

Query: 292  AVKQNTRRYTNMVSDVVYEMLPDYKF--KEVVAKDSLDVYIEHRIML 426
             VK N       ++   YE   D++F  K+V+   +++  +E+R+ L
Sbjct: 2108 VVKMNKWIEQTYLTPSNYEPSNDFQFNWKQVLTYSTIEQSLENRLFL 2154


>UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured
           haloarchaeon|Rep: MCM family protein - uncultured
           haloarchaeon
          Length = 647

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 13/36 (36%), Positives = 22/36 (61%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IR ++A+ I  L  + GI+++ T+VKP   V  + C
Sbjct: 130 IRNLRAKDINTLVGIDGIISKVTEVKPKFTVVVFQC 165


>UniRef50_UPI000058665D Cluster: PREDICTED: similar to LOC495125
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC495125 protein -
           Strongylocentrotus purpuratus
          Length = 188

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
 Frame = +1

Query: 64  RQQLFE*HISNKM--AMRDYTADKESFKNFFVDFCQTDDEGKKYFKYAEQLTKVAHREQI 237
           +Q+  E  +S ++  A ++ T +K   +   ++   T+ E  K  K+A    K AH+E  
Sbjct: 34  KQEFLEGKVSKELVIAKQNGTKNKREAQREALENANTNAEVLKNMKFASTALKTAHKEMG 93

Query: 238 AFEVD--LDDLHEMNEDLTE 291
             +VD  + D+HE  E  TE
Sbjct: 94  VEDVDDLMADVHEQMELATE 113


>UniRef50_Q91GJ2 Cluster: Putative uncharacterized protein; n=1;
           Epiphyas postvittana NPV|Rep: Putative uncharacterized
           protein - Epiphyas postvittana nucleopolyhedrovirus
           (EppoMNPV)
          Length = 881

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 32/128 (25%), Positives = 54/128 (42%), Gaps = 3/128 (2%)
 Frame = +1

Query: 184 KYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPD- 360
           K    AE+ TK  H E       +  L  +N+++ E V     +Y N   +   E L D 
Sbjct: 400 KALPVAEETTKNLHEELRGERATITKLQRINQEVQEKVNDLQTKYNNAQDE--NESLNDE 457

Query: 361 -YKFKEVVAK-DSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFEVYFKDLSTS 534
             K   ++ K +SL   +E    L+ +N R+   + D  N +  E  RR     + L  +
Sbjct: 458 ISKLSPLIQKTESLKEEVER---LDKKNKRLKQNLADEHNNFLEEQQRRQNAQ-QSLQNT 513

Query: 535 KSVPIREV 558
           + + I+ V
Sbjct: 514 EDLQIQNV 521


>UniRef50_Q54S44 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 796

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 22/101 (21%), Positives = 45/101 (44%)
 Frame = +1

Query: 280 DLTEAVKQNTRRYTNMVSDVVYEMLPDYKFKEVVAKDSLDVYIEHRIMLEARNHRIPGEM 459
           D++  +K+N     ++  D +YE+L DY+   +      D   + +   +  N R   ++
Sbjct: 2   DISGFLKENKESLKDLKEDDIYEILEDYEIDNI-----NDPKQKIKFFKKVENKRKRLKI 56

Query: 460 RDPRNRYPPELIRRFEVYFKDLSTSKSVPIREVKAEHIGKL 582
            + +NR   E  + F + F++        + E K E + KL
Sbjct: 57  EEEKNRMSEEEKKEFLIKFEEEKQKLKTEVEEEKKEFLIKL 97


>UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
           thermophila SB210|Rep: MCM2/3/5 family protein -
           Tetrahymena thermophila SB210
          Length = 797

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 15/53 (28%), Positives = 31/53 (58%)
 Frame = +1

Query: 496 RRFEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           +R +V  +  +  +SV +R++KA  I K   V+G+V + + V+ ++   T+ C
Sbjct: 153 KRKKVIVRLYNYDQSVQLRDIKANIINKYLQVKGVVLKTSPVQVMINEMTFQC 205


>UniRef50_Q5V011 Cluster: MCM / cell division control protein 21;
           n=2; Halobacteriaceae|Rep: MCM / cell division control
           protein 21 - Haloarcula marismortui (Halobacterium
           marismortui)
          Length = 681

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 14/30 (46%), Positives = 20/30 (66%)
 Frame = +1

Query: 565 EHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           E+IG+L  +RG V + +DVKP L  A + C
Sbjct: 106 ENIGQLLDIRGQVQKVSDVKPRLTEAVWEC 135


>UniRef50_A3CTI4 Cluster: CRISPR-associated protein Cas1; n=1;
           Methanoculleus marisnigri JR1|Rep: CRISPR-associated
           protein Cas1 - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 392

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
 Frame = +1

Query: 235 IAFEVDLDDLHEMNEDLTEAV-KQNTRRYTNMVSDVVYEML-----PDYKFKEVVAKDSL 396
           I +  +LD LH+  E+L+ +V  +N RR + + +D+ YE+L     P+  F+   ++  L
Sbjct: 210 IFYAGELDFLHQAREELSASVTMENLRRLSRLTTDMYYEILSRTLPPELGFRRRTSRPYL 269

Query: 397 D 399
           D
Sbjct: 270 D 270


>UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1;
           Tetrahymena thermophila SB210|Rep: MCM2/3/5 family
           protein - Tetrahymena thermophila SB210
          Length = 730

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 16/38 (42%), Positives = 24/38 (63%)
 Frame = +1

Query: 502 FEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCT 615
           F+V+   +ST     +R++KA  I KL TV GI+T+ T
Sbjct: 114 FQVFL--ISTQDPKNLRDIKASSISKLITVSGIITQAT 149


>UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 17 SCAF14597, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 546

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 544 PIREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           P+R V+A   G+L  V+G V R + ++PL     + C
Sbjct: 119 PLRMVRASVFGRLVCVKGTVVRVSSIRPLCTRMAFRC 155


>UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF15020,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 965

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 13/36 (36%), Positives = 21/36 (58%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           IR ++  H+ +L    G+V+ CT V P L +  Y+C
Sbjct: 303 IRSLRQLHLNQLIRTSGVVSSCTGVLPQLGMVKYNC 338


>UniRef50_Q6JT33 Cluster: NADH-ubiquinone oxidoreductase chain 1;
           n=12; Araneae|Rep: NADH-ubiquinone oxidoreductase chain
           1 - Heptathela hangzhouensis
          Length = 304

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 15/33 (45%), Positives = 20/33 (60%)
 Frame = -3

Query: 500 LLISSGGYLFLGSLISPGILWFLASNIILCSMY 402
           LL+ S  YL +  LI   ILWF   N+IL +M+
Sbjct: 151 LLMISNSYLLIDILIYQEILWFFLGNLILLTMW 183


>UniRef50_A5K611 Cluster: DNA replication licensing factor,
           putative; n=1; Plasmodium vivax|Rep: DNA replication
           licensing factor, putative - Plasmodium vivax
          Length = 1310

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 13/36 (36%), Positives = 22/36 (61%)
 Frame = +1

Query: 547 IREVKAEHIGKLXTVRGIVTRCTDVKPLLVVATYSC 654
           ++E++++HIGK  +  GI+TR  + K L     Y C
Sbjct: 337 LQEIRSKHIGKFVSTEGIITRVGEKKILEECKKYRC 372


>UniRef50_Q6BT17 Cluster: Similar to CA1866|IPF7647 Candida albicans
           IPF7647 unknown function; n=1; Debaryomyces
           hansenii|Rep: Similar to CA1866|IPF7647 Candida albicans
           IPF7647 unknown function - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 704

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 24/111 (21%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
 Frame = +1

Query: 184 KYFKYAEQLTKVAHREQIAFEVDLDDLHEMNEDLTEAVKQNTRRYTNMVSDVVYEMLPDY 363
           K+F+Y EQ+    H  Q  ++  ++     +E+L+  V + T  + +     V+   P+ 
Sbjct: 102 KHFQYLEQIKGKKHIFQYLYDGSIEGEANKSEELSTQVAEETEFHKHAFK--VFNPYPNI 159

Query: 364 KFKE---VVAKDSLDVYIEHRIMLEARNHRIPGEMRDPRNRYPPELIRRFE 507
           K  E    V ++SL++ +     ++    ++ G     +N Y  EL   F+
Sbjct: 160 KGDEKKCSVIENSLNLEVSESKTMQVSLEKVVGNFVTQKNEYYQELSPFFQ 210


>UniRef50_P24279 Cluster: DNA replication licensing factor MCM3;
           n=6; Saccharomycetales|Rep: DNA replication licensing
           factor MCM3 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 971

 Score = 32.7 bits (71), Expect = 7.9
 Identities = 15/45 (33%), Positives = 29/45 (64%)
 Frame = +1

Query: 502 FEVYFKDLSTSKSVPIREVKAEHIGKLXTVRGIVTRCTDVKPLLV 636
           +++ FK    + ++  R + A+H+ KL +V GIVT+ + V+P L+
Sbjct: 153 WKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLI 197


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 605,110,682
Number of Sequences: 1657284
Number of extensions: 11865955
Number of successful extensions: 36533
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 35213
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36511
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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