Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_F09
(678 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferas... 308 9e-84
CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein. 308 9e-84
BC020790-1|AAH20790.1| 331|Homo sapiens Rab geranylgeranyltrans... 308 9e-84
AL357314-5|CAI22393.1| 331|Homo sapiens Rab geranylgeranyltrans... 308 9e-84
AB209023-1|BAD92260.1| 320|Homo sapiens Rab geranylgeranyltrans... 308 9e-84
U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferas... 307 3e-83
Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl transf... 305 9e-83
AL357314-4|CAI22392.1| 152|Homo sapiens Rab geranylgeranyltrans... 206 4e-53
L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transfer... 103 8e-22
L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transfer... 103 8e-22
BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CA... 103 8e-22
L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase... 62 2e-09
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 32 2.2
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 32 2.2
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 32 2.2
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 31 5.0
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 30 8.7
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 30 8.7
>X98001-1|CAA66638.1| 331|Homo sapiens geranylgeranyl transferase
II protein.
Length = 331
Score = 308 bits (757), Expect = 9e-84
Identities = 137/202 (67%), Positives = 163/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>CR456941-1|CAG33222.1| 331|Homo sapiens RABGGTB protein.
Length = 331
Score = 308 bits (757), Expect = 9e-84
Identities = 137/202 (67%), Positives = 163/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>BC020790-1|AAH20790.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 308 bits (757), Expect = 9e-84
Identities = 137/202 (67%), Positives = 163/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>AL357314-5|CAI22393.1| 331|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 331
Score = 308 bits (757), Expect = 9e-84
Identities = 137/202 (67%), Positives = 163/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>AB209023-1|BAD92260.1| 320|Homo sapiens Rab
geranylgeranyltransferase, beta subunit variant protein.
Length = 320
Score = 308 bits (757), Expect = 9e-84
Identities = 137/202 (67%), Positives = 163/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 38.3 bits (85), Expect = 0.025
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILY 364
+W L +++++G+ + +E + FI CQD E+GG + G D H +Y
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPG-DMHFIY 289
>U49245-1|AAA91473.1| 331|Homo sapiens geranylgeranyl transferase
type II beta-subunit protein.
Length = 331
Score = 307 bits (753), Expect = 3e-83
Identities = 136/202 (67%), Positives = 162/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV +LL +LDAI++ K +EFVLSCMNFDG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATFALLGKLDAINVEKAIEFVLSCMNFDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>Y08201-1|CAA69383.1| 331|Homo sapiens rab geranylgeranyl
transferase protein.
Length = 331
Score = 305 bits (749), Expect = 9e-83
Identities = 136/202 (67%), Positives = 162/202 (80%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQH-ECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDG 610
V Y+ LQ+EDGSF GD WGEIDTRFSFCAV L+LL +LDAI++ K +EFVLSCMN DG
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNSDG 179
Query: 611 GFGSKPGSESHAGLIYCCVGTL 676
GFG +PGSESHAG IYCC G L
Sbjct: 180 GFGCRPGSESHAGQIYCCTGFL 201
Score = 37.9 bits (84), Expect = 0.033
Identities = 18/59 (30%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Frame = +2
Query: 221 YWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGH--DP-HILYTLSAVQVL 388
+W L +++++G+ + +E + FI CQD E+GG + G DP H L+ ++ + +L
Sbjct: 243 WWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLL 301
>AL357314-4|CAI22392.1| 152|Homo sapiens Rab
geranylgeranyltransferase, beta subunit protein.
Length = 152
Score = 206 bits (504), Expect = 4e-53
Identities = 93/147 (63%), Positives = 114/147 (77%)
Frame = +2
Query: 71 MSFTTKDVVLKEDRPKTLLLQKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELM 250
M KDV++K D P TLLL+KH+DY+ASYG KDDYEYCM+EYLRMSGIYW LT M+LM
Sbjct: 1 MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLM 60
Query: 251 GQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGI 430
GQ RM +E+I+ FI CQ E GGISASIGHDPH+LYTLSAVQ+L +YD ++ +D+ +
Sbjct: 61 GQLHRMNREEILAFIKSCQ-HECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKV 119
Query: 431 VRYIVSLQQEDGSFYGDKWGEIDTRFS 511
V Y+ LQ+EDGSF GD WG + RFS
Sbjct: 120 VEYVKGLQKEDGSFAGDIWGNV--RFS 144
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/78 (29%), Positives = 38/78 (48%)
Frame = +2
Query: 383 VLAMYDRLDAVDIEGIVRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDAID 562
V+ + +L ++ E I+ +I S Q E G + ++ AV L+L ++ ID
Sbjct: 56 VMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVID 115
Query: 563 INKTVEFVLSCMNFDGGF 616
+NK VE+V DG F
Sbjct: 116 VNKVVEYVKGLQKEDGSF 133
>L10414-1|AAA86286.1| 387|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 387
Score = 103 bits (246), Expect = 8e-22
Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 4/186 (2%)
Frame = +2
Query: 131 QKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELMGQS-SRMPKEDIIEFITQCQ 307
+KH YL GL + Y + R YW L ++EL+ + ++ D+ +F+ CQ
Sbjct: 26 EKHFHYLKR-GLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQ 84
Query: 308 DSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDI---EGIVRYIVSLQQEDGSFYG 478
E GG G PH+ T +AV L + +A DI E +++Y+ SL+Q DGSF
Sbjct: 85 SPE-GGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLM 143
Query: 479 DKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIY 658
GE+D R ++CA SL + T E++ C N++GG G PG E+H G +
Sbjct: 144 HVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTF 203
Query: 659 CCVGTL 676
C + L
Sbjct: 204 CGLAAL 209
Score = 39.5 bits (88), Expect = 0.011
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 EDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGIVRYIVSLQ 454
E E+I +CQ+ E GGI G + H YT + L + R +++++ +++++ S Q
Sbjct: 173 EGTAEWIARCQNWE-GGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQ 231
Query: 455 Q-EDGSFYGDKWGEIDTRFSFCAVMCLSLLQR 547
+G F G +D +SF L LL R
Sbjct: 232 MLFEGGFQGRCNKLVDGCYSFWQAGLLPLLHR 263
>L00635-1|AAA35854.1| 437|Homo sapiens farnesyl-protein transferase
beta-subunit protein.
Length = 437
Score = 103 bits (246), Expect = 8e-22
Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 4/186 (2%)
Frame = +2
Query: 131 QKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELMGQS-SRMPKEDIIEFITQCQ 307
+KH YL GL + Y + R YW L ++EL+ + ++ D+ +F+ CQ
Sbjct: 76 EKHFHYLKR-GLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQ 134
Query: 308 DSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDI---EGIVRYIVSLQQEDGSFYG 478
E GG G PH+ T +AV L + +A DI E +++Y+ SL+Q DGSF
Sbjct: 135 SPE-GGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLM 193
Query: 479 DKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIY 658
GE+D R ++CA SL + T E++ C N++GG G PG E+H G +
Sbjct: 194 HVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTF 253
Query: 659 CCVGTL 676
C + L
Sbjct: 254 CGLAAL 259
Score = 40.7 bits (91), Expect = 0.005
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 EDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGIVRYIVSLQ 454
E E+I +CQ+ E GGI G + H YT + L + R +++++ +++++ S Q
Sbjct: 223 EGTAEWIARCQNWE-GGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQ 281
Query: 455 QE-DGSFYGDKWGEIDTRFSFCAVMCLSLLQR 547
+G F G +D +SF L LL R
Sbjct: 282 MRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHR 313
>BC020232-1|AAH20232.1| 437|Homo sapiens farnesyltransferase, CAAX
box, beta protein.
Length = 437
Score = 103 bits (246), Expect = 8e-22
Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 4/186 (2%)
Frame = +2
Query: 131 QKHSDYLASYGLNKDDYEYCMTEYLRMSGIYWSLTAMELMGQS-SRMPKEDIIEFITQCQ 307
+KH YL GL + Y + R YW L ++EL+ + ++ D+ +F+ CQ
Sbjct: 76 EKHFHYLKR-GLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQ 134
Query: 308 DSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDI---EGIVRYIVSLQQEDGSFYG 478
E GG G PH+ T +AV L + +A DI E +++Y+ SL+Q DGSF
Sbjct: 135 SPE-GGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLM 193
Query: 479 DKWGEIDTRFSFCAVMCLSLLQRLDAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIY 658
GE+D R ++CA SL + T E++ C N++GG G PG E+H G +
Sbjct: 194 HVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTF 253
Query: 659 CCVGTL 676
C + L
Sbjct: 254 CGLAAL 259
Score = 40.7 bits (91), Expect = 0.005
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = +2
Query: 275 EDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVLAMYDRLDAVDIEGIVRYIVSLQ 454
E E+I +CQ+ E GGI G + H YT + L + R +++++ +++++ S Q
Sbjct: 223 EGTAEWIARCQNWE-GGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQ 281
Query: 455 QE-DGSFYGDKWGEIDTRFSFCAVMCLSLLQR 547
+G F G +D +SF L LL R
Sbjct: 282 MRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHR 313
>L25441-1|AAA35888.1| 377|Homo sapiens geranylgeranyltransferase
type I beta-subunit protein.
Length = 377
Score = 61.7 bits (143), Expect = 2e-09
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Frame = +2
Query: 353 HILYTLSAVQVLAMY-DRLDAVDIEGIVRYIVSLQQEDGSFYGDKWG-EIDTRFSFCAVM 526
HI T + + L + D L V+ E + + +LQ EDGSF G E D RF +CA
Sbjct: 121 HIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASC 180
Query: 527 CLSLLQRLDAIDINKTVEFVLSCMNFDGGFGSKPGSESHAGLIYCCVGTL 676
+L +D+ K + ++ M++D G G ESH G +C + +L
Sbjct: 181 ICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASL 230
Score = 37.1 bits (82), Expect = 0.057
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Frame = +2
Query: 209 MSGIYWSLTAMELMGQSSRMPKEDIIEFITQCQDSESGGISASIGHDPHILYTLSAVQVL 388
M +Y + ++ S M + I +I + S G++ G + H T + L
Sbjct: 172 MRFVYCASCICYMLNNWSGMDMKKAITYIRRSM-SYDNGLAQGAGLESHGGSTFCGIASL 230
Query: 389 AMYDRLDAV----DIEGIVRYIVSLQQEDGSFYGDKWGEIDTRFSFCAVMCLSLLQRLDA 556
+ +L+ V ++ I R+ + ++Q++G ++G +DT +SF L LL+
Sbjct: 231 CLMGKLEEVFSEKELNRIKRWCI-MRQQNG-YHGRPNKPVDTCYSFWVGATLKLLKIFQY 288
Query: 557 IDINKTVEFVLSCMN-FDGGFGSKPGSESHA 646
+ K ++LS + GGF P S A
Sbjct: 289 TNFEKNRNYILSTQDRLVGGFAKWPDSHPDA 319
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 31.9 bits (69), Expect = 2.2
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Frame = -1
Query: 618 PNPPSKFMQLSTNSTVLLMSMASNRCKSDRHITAQKENLVSISPHXXXXXXXXXXXKETM 439
P+P + ST S+V +S ++ +S R +++ + +VS SP+ +
Sbjct: 1541 PSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAV 1600
Query: 438 YLTIPSISTASNLSYIASTCTALNVYSMC--GSCPMLAEIPPLS----LSWHCVMNSIIS 277
P ASN ++ + T S+ S M P S S SII+
Sbjct: 1601 TEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIIT 1660
Query: 276 SLGILDDCPMSSIAVKLQ*IPDILRYSVIQYS*SSLFKP 160
S L P+ S+ ++ D++ + I + SSL P
Sbjct: 1661 SAAPLISSPLKSVVSPVKSAVDVISSAKITMA-SSLSSP 1698
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 31.9 bits (69), Expect = 2.2
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Frame = -1
Query: 618 PNPPSKFMQLSTNSTVLLMSMASNRCKSDRHITAQKENLVSISPHXXXXXXXXXXXKETM 439
P+P + ST S+V +S ++ +S R +++ + +VS SP+ +
Sbjct: 1541 PSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAV 1600
Query: 438 YLTIPSISTASNLSYIASTCTALNVYSMC--GSCPMLAEIPPLS----LSWHCVMNSIIS 277
P ASN ++ + T S+ S M P S S SII+
Sbjct: 1601 TEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIIT 1660
Query: 276 SLGILDDCPMSSIAVKLQ*IPDILRYSVIQYS*SSLFKP 160
S L P+ S+ ++ D++ + I + SSL P
Sbjct: 1661 SAAPLISSPLKSVVSPVKSAVDVISSAKITMA-SSLSSP 1698
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 31.9 bits (69), Expect = 2.2
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Frame = -1
Query: 618 PNPPSKFMQLSTNSTVLLMSMASNRCKSDRHITAQKENLVSISPHXXXXXXXXXXXKETM 439
P+P + ST S+V +S ++ +S R +++ + +VS SP+ +
Sbjct: 1541 PSPIKSTLGASTTSSVKSISDVASPIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAPAV 1600
Query: 438 YLTIPSISTASNLSYIASTCTALNVYSMC--GSCPMLAEIPPLS----LSWHCVMNSIIS 277
P ASN ++ + T S+ S M P S S SII+
Sbjct: 1601 TEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIIT 1660
Query: 276 SLGILDDCPMSSIAVKLQ*IPDILRYSVIQYS*SSLFKP 160
S L P+ S+ ++ D++ + I + SSL P
Sbjct: 1661 SAAPLISSPLKSVVSPVKSAVDVISSAKITMA-SSLSSP 1698
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 30.7 bits (66), Expect = 5.0
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
Frame = -1
Query: 618 PNPPSKFMQLSTNSTVLLMSMASNRCKSDRHITAQKENLVSISPHXXXXXXXXXXXKETM 439
P+P + ST S+V +S ++ +S R +++ + +VS SP+ +
Sbjct: 1546 PSPIKSTLGASTTSSVKSISDVASPIRSLRTMSSPIKTVVSQSPYNIQVSSGTLARAPAV 1605
Query: 438 YLTIPSISTASNLSYIASTCTALNVYSMC--GSCPMLAEIPPLS----LSWHCVMNSIIS 277
P ASN ++ + T S+ S M P S S SII+
Sbjct: 1606 TEATPLKGLASNSTFSSRTSPVTTAGSLLERSSITMTPPASPKSNINMYSSSLPFKSIIT 1665
Query: 276 SLGILDDCPMSSIAVKLQ*IPDILRYSVIQYS*SSLFKP 160
S L P+ S+ ++ D++ + I + SSL P
Sbjct: 1666 SAAPLISSPLKSVVSPVKSRVDVISSAKITMA-SSLSSP 1703
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 29.9 bits (64), Expect = 8.7
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Frame = -1
Query: 651 RPAWLSDPGLEPNPPSKF--MQLSTNSTVL--LMSMASNRCKSDRHITAQKE 508
+P SDP EP+PP K +++ NS L L + K D +IT+ +E
Sbjct: 19715 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 19766
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 29.9 bits (64), Expect = 8.7
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 4/52 (7%)
Frame = -1
Query: 651 RPAWLSDPGLEPNPPSKF--MQLSTNSTVL--LMSMASNRCKSDRHITAQKE 508
+P SDP EP+PP K +++ NS L L + K D +IT+ +E
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYRE 12342
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,703,663
Number of Sequences: 237096
Number of extensions: 1999021
Number of successful extensions: 4307
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4114
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4262
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7671262118
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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