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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P01_F_E20
         (517 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X68836-1|CAA48726.1|  395|Homo sapiens S-adenosylmethionine synt...   273   3e-73
DQ083239-1|AAY85355.1|  395|Homo sapiens methionine adenosyltran...   273   3e-73
BC001854-1|AAH01854.1|  395|Homo sapiens methionine adenosyltran...   273   3e-73
BC001686-1|AAH01686.1|  395|Homo sapiens methionine adenosyltran...   273   3e-73
AC016753-1|AAY24339.1|  395|Homo sapiens unknown protein.             273   3e-73
X69078-1|CAA48822.1|  395|Homo sapiens methionine adenosyltransf...   263   3e-70
D49357-1|BAA08355.1|  395|Homo sapiens S-adenosylmethionine synt...   263   3e-70
BC018359-1|AAH18359.1|  395|Homo sapiens methionine adenosyltran...   263   3e-70
AL359195-2|CAI13695.1|  395|Homo sapiens methionine adenosyltran...   263   3e-70
AL359195-3|CAI13696.1|  145|Homo sapiens methionine adenosyltran...   117   3e-26
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.                29   9.7  
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei...    29   9.7  
AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein.            29   9.7  
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3...    29   9.7  
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3...    29   9.7  

>X68836-1|CAA48726.1|  395|Homo sapiens S-adenosylmethionine
           synthetase protein.
          Length = 395

 Score =  273 bits (669), Expect = 3e-73
 Identities = 126/159 (79%), Positives = 143/159 (89%), Gaps = 1/159 (0%)
 Frame = +3

Query: 42  QTNG-HSYXMEAGSVFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKT 218
           Q NG H   +E G+ FLFTSESVGEGHP K+CDQISDA+LDAHL QDPDAKVACET+ KT
Sbjct: 4   QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKT 62

Query: 219 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 398
           GM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GVH
Sbjct: 63  GMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVH 122

Query: 399 ENRNDEEVGAGDQGLMFGYATDETEECMPLTVXLAHKLN 515
            +RN+E++GAGDQGLMFGYATDETEECMPLT+ LAHKLN
Sbjct: 123 LDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLN 161


>DQ083239-1|AAY85355.1|  395|Homo sapiens methionine
           adenosyltransferase II protein.
          Length = 395

 Score =  273 bits (669), Expect = 3e-73
 Identities = 126/159 (79%), Positives = 143/159 (89%), Gaps = 1/159 (0%)
 Frame = +3

Query: 42  QTNG-HSYXMEAGSVFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKT 218
           Q NG H   +E G+ FLFTSESVGEGHP K+CDQISDA+LDAHL QDPDAKVACET+ KT
Sbjct: 4   QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKT 62

Query: 219 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 398
           GM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GVH
Sbjct: 63  GMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVH 122

Query: 399 ENRNDEEVGAGDQGLMFGYATDETEECMPLTVXLAHKLN 515
            +RN+E++GAGDQGLMFGYATDETEECMPLT+ LAHKLN
Sbjct: 123 LDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLN 161


>BC001854-1|AAH01854.1|  395|Homo sapiens methionine
           adenosyltransferase II, alpha protein.
          Length = 395

 Score =  273 bits (669), Expect = 3e-73
 Identities = 126/159 (79%), Positives = 143/159 (89%), Gaps = 1/159 (0%)
 Frame = +3

Query: 42  QTNG-HSYXMEAGSVFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKT 218
           Q NG H   +E G+ FLFTSESVGEGHP K+CDQISDA+LDAHL QDPDAKVACET+ KT
Sbjct: 4   QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKT 62

Query: 219 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 398
           GM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GVH
Sbjct: 63  GMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVH 122

Query: 399 ENRNDEEVGAGDQGLMFGYATDETEECMPLTVXLAHKLN 515
            +RN+E++GAGDQGLMFGYATDETEECMPLT+ LAHKLN
Sbjct: 123 LDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLN 161


>BC001686-1|AAH01686.1|  395|Homo sapiens methionine
           adenosyltransferase II, alpha protein.
          Length = 395

 Score =  273 bits (669), Expect = 3e-73
 Identities = 126/159 (79%), Positives = 143/159 (89%), Gaps = 1/159 (0%)
 Frame = +3

Query: 42  QTNG-HSYXMEAGSVFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKT 218
           Q NG H   +E G+ FLFTSESVGEGHP K+CDQISDA+LDAHL QDPDAKVACET+ KT
Sbjct: 4   QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKT 62

Query: 219 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 398
           GM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GVH
Sbjct: 63  GMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVH 122

Query: 399 ENRNDEEVGAGDQGLMFGYATDETEECMPLTVXLAHKLN 515
            +RN+E++GAGDQGLMFGYATDETEECMPLT+ LAHKLN
Sbjct: 123 LDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLN 161


>AC016753-1|AAY24339.1|  395|Homo sapiens unknown protein.
          Length = 395

 Score =  273 bits (669), Expect = 3e-73
 Identities = 126/159 (79%), Positives = 143/159 (89%), Gaps = 1/159 (0%)
 Frame = +3

Query: 42  QTNG-HSYXMEAGSVFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKT 218
           Q NG H   +E G+ FLFTSESVGEGHP K+CDQISDA+LDAHL QDPDAKVACET+ KT
Sbjct: 4   QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKT 62

Query: 219 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 398
           GM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA GVH
Sbjct: 63  GMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVH 122

Query: 399 ENRNDEEVGAGDQGLMFGYATDETEECMPLTVXLAHKLN 515
            +RN+E++GAGDQGLMFGYATDETEECMPLT+ LAHKLN
Sbjct: 123 LDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLN 161


>X69078-1|CAA48822.1|  395|Homo sapiens methionine
           adenosyltransferase protein.
          Length = 395

 Score =  263 bits (644), Expect = 3e-70
 Identities = 117/145 (80%), Positives = 136/145 (93%)
 Frame = +3

Query: 81  VFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKAN 260
           VF+FTSESVGEGHP K+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCGEITS A 
Sbjct: 17  VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAM 76

Query: 261 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQG 440
           VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQG
Sbjct: 77  VDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQG 136

Query: 441 LMFGYATDETEECMPLTVXLAHKLN 515
           LMFGYATDETEECMPLT+ LAHKLN
Sbjct: 137 LMFGYATDETEECMPLTIILAHKLN 161


>D49357-1|BAA08355.1|  395|Homo sapiens S-adenosylmethionine
           synthetase protein.
          Length = 395

 Score =  263 bits (644), Expect = 3e-70
 Identities = 117/145 (80%), Positives = 136/145 (93%)
 Frame = +3

Query: 81  VFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKAN 260
           VF+FTSESVGEGHP K+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCGEITS A 
Sbjct: 17  VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAM 76

Query: 261 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQG 440
           VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQG
Sbjct: 77  VDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQG 136

Query: 441 LMFGYATDETEECMPLTVXLAHKLN 515
           LMFGYATDETEECMPLT+ LAHKLN
Sbjct: 137 LMFGYATDETEECMPLTIILAHKLN 161


>BC018359-1|AAH18359.1|  395|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 395

 Score =  263 bits (644), Expect = 3e-70
 Identities = 117/145 (80%), Positives = 136/145 (93%)
 Frame = +3

Query: 81  VFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKAN 260
           VF+FTSESVGEGHP K+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCGEITS A 
Sbjct: 17  VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAM 76

Query: 261 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQG 440
           VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQG
Sbjct: 77  VDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQG 136

Query: 441 LMFGYATDETEECMPLTVXLAHKLN 515
           LMFGYATDETEECMPLT+ LAHKLN
Sbjct: 137 LMFGYATDETEECMPLTIILAHKLN 161


>AL359195-2|CAI13695.1|  395|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 395

 Score =  263 bits (644), Expect = 3e-70
 Identities = 117/145 (80%), Positives = 136/145 (93%)
 Frame = +3

Query: 81  VFLFTSESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKAN 260
           VF+FTSESVGEGHP K+CDQISDA+LDAHL QDP+AKVACET+ KTGMVLLCGEITS A 
Sbjct: 17  VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAM 76

Query: 261 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQG 440
           VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQG
Sbjct: 77  VDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQG 136

Query: 441 LMFGYATDETEECMPLTVXLAHKLN 515
           LMFGYATDETEECMPLT+ LAHKLN
Sbjct: 137 LMFGYATDETEECMPLTIILAHKLN 161


>AL359195-3|CAI13696.1|  145|Homo sapiens methionine
           adenosyltransferase I, alpha protein.
          Length = 145

 Score =  117 bits (281), Expect = 3e-26
 Identities = 53/76 (69%), Positives = 66/76 (86%), Gaps = 3/76 (3%)
 Frame = +3

Query: 297 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGAGDQGLMFGYATDE 467
           H+  D ++K   GFD+KTC+V++AL+QQSP+IA  VH +RN+E+VGAGDQGLMFGYATDE
Sbjct: 23  HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDE 82

Query: 468 TEECMPLTVXLAHKLN 515
           TEECMPLT+ LAHKLN
Sbjct: 83  TEECMPLTIILAHKLN 98



 Score = 72.9 bits (171), Expect = 6e-13
 Identities = 41/81 (50%), Positives = 48/81 (59%)
 Frame = +3

Query: 99  ESVGEGHPXKMCDQISDAILDAHLNQDPDAKVACETITKTGMVLLCGEITSKANVDYQKV 278
           ESVGEGHP K+CDQISDA+LDAHL QDP+AKVAC    KT  VL+  E  S        +
Sbjct: 1   ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHL 60

Query: 279 VRETVKHIGYDDSSKGFDYKT 341
            R   + +G  D    F Y T
Sbjct: 61  DRNE-EDVGAGDQGLMFGYAT 80


>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
          Length = 3113

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 7    ACRXLQKCMDTRKPTDTVMXWKLDQYFCSHRNLLARV 117
            AC  L+K +   K  ++ +  KL+ + C H+ LL RV
Sbjct: 1823 ACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV 1859


>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
            protein.
          Length = 3210

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 7    ACRXLQKCMDTRKPTDTVMXWKLDQYFCSHRNLLARV 117
            AC  L+K +   K  ++ +  KL+ + C H+ LL RV
Sbjct: 1920 ACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV 1956


>AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein.
          Length = 1211

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 14/27 (51%), Positives = 15/27 (55%)
 Frame = -1

Query: 451  PNIKPWSPAPTSSSFLFSCTPAAMFGD 371
            P+  PWSPA TSS  L S  P    GD
Sbjct: 1178 PDEPPWSPAATSSGNLSSRGPGPATGD 1204


>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
            350/400ka (mitosin) protein.
          Length = 3114

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 7    ACRXLQKCMDTRKPTDTVMXWKLDQYFCSHRNLLARV 117
            AC  L+K +   K  ++ +  KL+ + C H+ LL RV
Sbjct: 1824 ACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV 1860


>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
            350/400ka (mitosin) protein.
          Length = 3114

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +1

Query: 7    ACRXLQKCMDTRKPTDTVMXWKLDQYFCSHRNLLARV 117
            AC  L+K +   K  ++ +  KL+ + C H+ LL RV
Sbjct: 1824 ACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRV 1860


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,293,044
Number of Sequences: 237096
Number of extensions: 1801181
Number of successful extensions: 3522
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3390
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3522
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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