BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fcaL-P01_F_C22 (741 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p... 210 3e-53 UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 p... 159 7e-38 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 142 1e-32 UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1... 136 5e-31 UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chai... 132 1e-29 UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-... 129 6e-29 UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP000... 125 1e-27 UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 121 2e-26 UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 103 6e-21 UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ... 95 2e-18 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 95 2e-18 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ... 93 6e-18 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 93 9e-18 UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketor... 92 2e-17 UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 91 3e-17 UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 89 8e-17 UniRef50_A2TF13 Cluster: 11-beta short-chain dehydrogenase reduc... 89 1e-16 UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 89 1e-16 UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;... 89 1e-16 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 88 2e-16 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 88 2e-16 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 87 4e-16 UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 87 4e-16 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR... 87 6e-16 UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam... 86 7e-16 UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR... 86 1e-15 UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; ... 86 1e-15 UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A7QUU9 Cluster: Chromosome chr1 scaffold_180, whole gen... 85 1e-15 UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero... 85 2e-15 UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15 UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R... 85 2e-15 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 85 2e-15 UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reducta... 85 2e-15 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q9LUF2 Cluster: 11-beta-hydroxysteroid dehydrogenase-li... 84 3e-15 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 84 4e-15 UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep... 83 5e-15 UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:... 83 5e-15 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 83 7e-15 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 83 7e-15 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 83 7e-15 UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR... 83 7e-15 UniRef50_Q0GJJ3 Cluster: 11-beta-hydroxysteroid dehydrogenase-li... 83 7e-15 UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A... 83 9e-15 UniRef50_Q0HN46 Cluster: Short-chain dehydrogenase/reductase SDR... 83 9e-15 UniRef50_A7DMA1 Cluster: Short-chain dehydrogenase/reductase SDR... 83 9e-15 UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH... 82 1e-14 UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q9LUF1 Cluster: 11-beta-hydroxysteroid dehydrogenase-li... 82 1e-14 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 82 2e-14 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 82 2e-14 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 82 2e-14 UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogena... 82 2e-14 UniRef50_Q1ARR8 Cluster: Short-chain dehydrogenase/reductase SDR... 82 2e-14 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 82 2e-14 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 82 2e-14 UniRef50_Q01LD3 Cluster: OSIGBa0132D06.4 protein; n=9; BEP clade... 82 2e-14 UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re... 81 2e-14 UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 81 2e-14 UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribact... 81 2e-14 UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena... 81 3e-14 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 81 3e-14 UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 81 3e-14 UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6... 81 4e-14 UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 81 4e-14 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 81 4e-14 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 81 4e-14 UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 80 5e-14 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 80 6e-14 UniRef50_Q128G0 Cluster: Short-chain dehydrogenase/reductase SDR... 80 6e-14 UniRef50_A6GPQ6 Cluster: Short chain dehydrogenase; n=1; Limnoba... 80 6e-14 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 80 6e-14 UniRef50_Q8YSW6 Cluster: Oxidoreductase; n=3; Nostocaceae|Rep: O... 79 9e-14 UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri... 79 9e-14 UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa... 79 9e-14 UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Microm... 79 9e-14 UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 79 9e-14 UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_Q01LD2 Cluster: OSIGBa0132D06.5 protein; n=2; Oryza sat... 79 9e-14 UniRef50_A7RI27 Cluster: Predicted protein; n=1; Nematostella ve... 79 9e-14 UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam... 79 9e-14 UniRef50_Q3IPT1 Cluster: Predicted dehydrogenase; n=2; Halobacte... 79 9e-14 UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 79 1e-13 UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacte... 79 1e-13 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1... 79 1e-13 UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 78 2e-13 UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 78 2e-13 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 78 2e-13 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 78 3e-13 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR... 78 3e-13 UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 78 3e-13 UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,... 77 3e-13 UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 77 3e-13 UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 77 3e-13 UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q2S733 Cluster: Short-chain dehydrogenase of various su... 77 5e-13 UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 77 5e-13 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q8YX01 Cluster: All1418 protein; n=4; Bacteria|Rep: All... 77 6e-13 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 6e-13 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 77 6e-13 UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR... 77 6e-13 UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core ... 77 6e-13 UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 76 8e-13 UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E... 76 8e-13 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 76 8e-13 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 76 1e-12 UniRef50_Q1DAW1 Cluster: Oxidoreductase, short-chain dehydrogena... 76 1e-12 UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 76 1e-12 UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 76 1e-12 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 76 1e-12 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 76 1e-12 UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillu... 75 1e-12 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 75 1e-12 UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 75 1e-12 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 75 2e-12 UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 75 2e-12 UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 75 2e-12 UniRef50_Q1VRQ5 Cluster: Short chain dehydrogenase; n=2; Flavoba... 75 2e-12 UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|... 75 2e-12 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 75 2e-12 UniRef50_UPI000023CB35 Cluster: hypothetical protein FG03285.1; ... 75 2e-12 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 75 2e-12 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 75 2e-12 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 75 2e-12 UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenas... 75 2e-12 UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 75 2e-12 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A1ZFM2 Cluster: Oxidoreductase; n=1; Microscilla marina... 75 2e-12 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 75 2e-12 UniRef50_Q7NK97 Cluster: Gll1581 protein; n=1; Gloeobacter viola... 74 3e-12 UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 74 3e-12 UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu... 74 3e-12 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 74 3e-12 UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 74 3e-12 UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductas... 74 3e-12 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 74 3e-12 UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=... 74 4e-12 UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_Q1NHB1 Cluster: Oxidoreductase; n=1; Sphingomonas sp. S... 74 4e-12 UniRef50_Q1ASB7 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A1UJQ6 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 74 4e-12 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta... 74 4e-12 UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb... 74 4e-12 UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 73 6e-12 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 73 6e-12 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 73 6e-12 UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12 UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain de... 73 6e-12 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 73 6e-12 UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 73 6e-12 UniRef50_A5FER5 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_UPI0000E49977 Cluster: PREDICTED: similar to dehydrogen... 73 7e-12 UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacter... 73 7e-12 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 73 7e-12 UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell... 73 7e-12 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 73 7e-12 UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 73 7e-12 UniRef50_Q3W2E5 Cluster: Short-chain dehydrogenase/reductase SDR... 73 7e-12 UniRef50_Q2C7C6 Cluster: Oxidoreductase, short-chain dehydrogena... 73 7e-12 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 73 7e-12 UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 73 7e-12 UniRef50_A6CPA0 Cluster: Short-chain dehydrogenase/reductase SDR... 73 7e-12 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 73 7e-12 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 73 1e-11 UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae... 73 1e-11 UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR... 73 1e-11 UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 73 1e-11 UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR... 73 1e-11 UniRef50_Q2R3W3 Cluster: Oxidoreductase, short chain dehydrogena... 73 1e-11 UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;... 73 1e-11 UniRef50_A6QZL8 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 73 1e-11 UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with dif... 72 1e-11 UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 72 1e-11 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 72 1e-11 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 72 1e-11 UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 72 1e-11 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0Z805 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 72 1e-11 UniRef50_A7RZW0 Cluster: Predicted protein; n=2; Nematostella ve... 72 1e-11 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 72 2e-11 UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogena... 72 2e-11 UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR... 72 2e-11 UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya... 72 2e-11 UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot... 72 2e-11 UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogena... 72 2e-11 UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR... 72 2e-11 UniRef50_Q9URX0 Cluster: Short chain dehydrogenase; n=1; Schizos... 72 2e-11 UniRef50_Q7RV91 Cluster: TETRAHYDROXYNAPHTHALENE REDUCTASE; n=12... 72 2e-11 UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 72 2e-11 UniRef50_UPI000023D9EA Cluster: hypothetical protein FG11198.1; ... 71 2e-11 UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomona... 71 2e-11 UniRef50_Q3DYV2 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q2MFL7 Cluster: SriL03.9; n=3; Actinomycetales|Rep: Sri... 71 2e-11 UniRef50_Q1INP7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A5GUC7 Cluster: Possible short chain dehydrogenase; n=5... 71 2e-11 UniRef50_A5D4R4 Cluster: Dehydrogenases with different specifici... 71 2e-11 UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein... 71 2e-11 UniRef50_A1SNX1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 71 2e-11 UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 71 2e-11 UniRef50_Q9MA93 Cluster: Glucose and ribitol dehydrogenase homol... 71 2e-11 UniRef50_Q9FZ42 Cluster: Glucose and ribitol dehydrogenase homol... 71 2e-11 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 71 2e-11 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 71 3e-11 UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ... 71 3e-11 UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena... 71 3e-11 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 71 3e-11 UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductas... 71 3e-11 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 71 3e-11 UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A7SXC4 Cluster: Predicted protein; n=2; Fungi/Metazoa g... 71 3e-11 UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 71 3e-11 UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb... 71 3e-11 UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 71 4e-11 UniRef50_Q1NAA1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_Q1GWK3 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_Q11C87 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_Q0RWG5 Cluster: Probable short chain dehydrogenase; n=2... 71 4e-11 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_A5FCR2 Cluster: Short-chain dehydrogenase/reductase SDR... 71 4e-11 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 71 4e-11 UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 71 4e-11 UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular... 71 4e-11 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 70 5e-11 UniRef50_Q7WPF5 Cluster: Putative short chain dehydrogenase; n=1... 70 5e-11 UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 70 5e-11 UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de... 70 5e-11 UniRef50_Q28SS4 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 70 5e-11 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 70 5e-11 UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 70 5e-11 UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central ... 70 5e-11 UniRef50_A1SCT9 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_A7PHJ9 Cluster: Chromosome chr17 scaffold_16, whole gen... 70 5e-11 UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan... 70 5e-11 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 70 7e-11 UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 70 7e-11 UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_Q21BL9 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 70 7e-11 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_A4ADP4 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_A1ZSH9 Cluster: Oxidoreductase, short-chain dehydrogena... 70 7e-11 UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR... 70 7e-11 UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 70 7e-11 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 69 9e-11 UniRef50_Q8KES3 Cluster: Sepiapterin reductase; n=11; Chlorobiac... 69 9e-11 UniRef50_Q3IVC8 Cluster: Short-chain alcohol dehydrogenases; n=2... 69 9e-11 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 69 9e-11 UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 69 9e-11 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11 UniRef50_A7MMI9 Cluster: Putative uncharacterized protein; n=1; ... 69 9e-11 UniRef50_A7B0B1 Cluster: Putative uncharacterized protein; n=1; ... 69 9e-11 UniRef50_A6DG05 Cluster: Short chain dehydrogenase; n=1; Lentisp... 69 9e-11 UniRef50_A3PSW5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 69 9e-11 UniRef50_A1IB60 Cluster: Short-chain alcohol dehydrogenase-like ... 69 9e-11 UniRef50_A0PLX0 Cluster: Carveol-like dehydrogenase; n=1; Mycoba... 69 9e-11 UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11 UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 9e-11 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 69 9e-11 UniRef50_Q9PH01 Cluster: Oxidoreductase; n=17; Proteobacteria|Re... 69 1e-10 UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl... 69 1e-10 UniRef50_Q89BG7 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo... 69 1e-10 UniRef50_Q81NI8 Cluster: Oxidoreductase, short-chain dehydrogena... 69 1e-10 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 69 1e-10 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 69 1e-10 UniRef50_Q7D7H4 Cluster: Oxidoreductase, short-chain dehydrogena... 69 1e-10 UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p... 69 1e-10 UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10 UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder... 69 1e-10 UniRef50_Q0SBJ1 Cluster: Probable short chain dehydrogenase; n=1... 69 1e-10 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q027N3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 69 1e-10 UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A4XEN1 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena... 69 2e-10 UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 69 2e-10 UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni... 69 2e-10 UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 2e-10 UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobac... 69 2e-10 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 69 2e-10 UniRef50_A3HT01 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 69 2e-10 UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR... 69 2e-10 UniRef50_A0JAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 2e-10 UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 2e-10 UniRef50_Q74GP9 Cluster: Oxidoreductase, short chain dehydrogena... 68 2e-10 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 68 2e-10 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q3VRG3 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q03ND1 Cluster: 3-oxoacyl-acyl carrier protein reductas... 68 2e-10 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10 UniRef50_A6W9E3 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 68 2e-10 UniRef50_A3VC22 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q2UFW9 Cluster: Dehydrogenases with different specifici... 68 2e-10 UniRef50_Q9HRV8 Cluster: Oxidoreductase homolog; n=1; Halobacter... 68 2e-10 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 68 2e-10 UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=... 68 2e-10 UniRef50_Q4S0T0 Cluster: Chromosome undetermined SCAF14779, whol... 68 3e-10 UniRef50_Q7N3C0 Cluster: Similar to pteridine reductase 1; n=1; ... 68 3e-10 UniRef50_Q3WGR0 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_A7IEU0 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_A5VH80 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_A5USZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 3e-10 UniRef50_A0NJV5 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 68 3e-10 UniRef50_Q5KIP0 Cluster: Oxidoreductase, putative; n=2; Basidiom... 68 3e-10 UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10 UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3;... 68 3e-10 UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 68 3e-10 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 68 3e-10 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 68 3e-10 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 68 3e-10 UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:... 67 4e-10 UniRef50_Q8UAP0 Cluster: Dehydrogenase; n=7; Bacteria|Rep: Dehyd... 67 4e-10 UniRef50_Q88T86 Cluster: Short-chain dehydrogenase/oxidoreductas... 67 4e-10 UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogena... 67 4e-10 UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 67 4e-10 UniRef50_Q0S3V2 Cluster: Short chain dehydrogenase; n=4; Bacteri... 67 4e-10 UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1... 67 4e-10 UniRef50_Q0REU7 Cluster: Putatine short chain dehydrogenase/redu... 67 4e-10 UniRef50_A6E7X1 Cluster: Short chain dehydrogenase; n=1; Pedobac... 67 4e-10 UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopire... 67 4e-10 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 67 4e-10 UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q8TTF8 Cluster: Cyclohexanol dehydrogenase; n=1; Methan... 67 4e-10 UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_UPI000023E5B7 Cluster: hypothetical protein FG10672.1; ... 67 5e-10 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 67 5e-10 UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 67 5e-10 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 67 5e-10 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 67 5e-10 UniRef50_O54218 Cluster: Oxidoreductase; n=1; Staphylococcus epi... 67 5e-10 UniRef50_A6E7M9 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 67 5e-10 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_A1UP20 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_A1TCY9 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 67 5e-10 UniRef50_Q54Q00 Cluster: Putative uncharacterized protein; n=7; ... 67 5e-10 UniRef50_A7RYX9 Cluster: Predicted protein; n=1; Nematostella ve... 67 5e-10 UniRef50_Q5KF96 Cluster: Peroxisomal hydratase-dehydrogenase-epi... 67 5e-10 UniRef50_Q8R6S8 Cluster: Dehydrogenases with different specifici... 66 6e-10 UniRef50_Q3IVH6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_Q41CQ8 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=... 66 6e-10 UniRef50_Q1H4T7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_Q0I7J4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 66 6e-10 UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 66 6e-10 UniRef50_A5UY97 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 66 6e-10 UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 66 6e-10 UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1... 66 6e-10 UniRef50_A1UJT5 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A1RDE7 Cluster: Putative Oxidoreductase, short chain de... 66 6e-10 UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 66 6e-10 UniRef50_A0RYU1 Cluster: Short-chain alcohol dehydrogenase; n=1;... 66 6e-10 UniRef50_Q12634 Cluster: Tetrahydroxynaphthalene reductase; n=23... 66 6e-10 UniRef50_UPI000045C012 Cluster: COG1028: Dehydrogenases with dif... 66 9e-10 UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;... 66 9e-10 UniRef50_Q2JDM5 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q937T4 Cluster: DcaC; n=2; Acinetobacter sp. ADP1|Rep: ... 66 9e-10 UniRef50_A6GMI9 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A5V309 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 66 9e-10 UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q9LUE4 Cluster: Similarity to oxidoreductase; n=1; Arab... 66 9e-10 UniRef50_Q1DSR4 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_P37694 Cluster: Ketoacyl reductase hetN; n=3; Nostocace... 66 9e-10 UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy... 66 1e-09 UniRef50_Q9KEP9 Cluster: Dehydrogenase/reductase family; n=12; B... 66 1e-09 UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici... 66 1e-09 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 66 1e-09 UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 66 1e-09 UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob... 66 1e-09 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 66 1e-09 UniRef50_Q0SFE0 Cluster: Probable short chain dehydrogenase; n=1... 66 1e-09 UniRef50_Q0S0Q5 Cluster: Probable oxidoreductase; n=2; Nocardiac... 66 1e-09 UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc... 66 1e-09 UniRef50_A6ECN3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A5NMG7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A1UD76 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A1D0L3 Cluster: Oxidoreductase, short-chain dehydrogena... 66 1e-09 UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacter... 66 1e-09 UniRef50_Q01373 Cluster: Peroxisomal hydratase-dehydrogenase-epi... 66 1e-09 UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb... 66 1e-09 UniRef50_Q9RUC2 Cluster: Oxidoreductase, short-chain dehydrogena... 65 1e-09 UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 65 1e-09 UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 65 1e-09 UniRef50_Q8EY16 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 65 1e-09 UniRef50_Q7NKQ6 Cluster: Glr1421 protein; n=10; Bacteria|Rep: Gl... 65 1e-09 UniRef50_Q1YRW1 Cluster: Pteridine reductase; n=1; gamma proteob... 65 1e-09 UniRef50_Q1ITR9 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q12BL9 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q0RX75 Cluster: Probable glucose dehydrogenase; n=1; Rh... 65 1e-09 UniRef50_Q0FPM7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 65 1e-09 UniRef50_A4XYR7 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A3PZY6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A1W2L0 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A1K1C4 Cluster: Short-chain dehydrogenase family protei... 65 1e-09 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 65 1e-09 UniRef50_Q9T0G0 Cluster: Putative oxidoreductase; n=3; Magnoliop... 65 1e-09 UniRef50_Q8LKV5 Cluster: Steroleosin-B; n=5; core eudicotyledons... 65 1e-09 UniRef50_Q17D91 Cluster: Short-chain dehydrogenase; n=2; Aedes a... 65 1e-09 UniRef50_A6S2H4 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09 UniRef50_Q8EXT7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 65 2e-09 UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr... 65 2e-09 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 2e-09 UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1; Thermob... 65 2e-09 UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 65 2e-09 UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ... 65 2e-09 >UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p - Drosophila melanogaster (Fruit fly) Length = 269 Score = 210 bits (513), Expect = 3e-53 Identities = 105/179 (58%), Positives = 126/179 (70%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--I 369 MNFAGKVV +K GA L+L GRNVENL+KV+ +C K + + + Sbjct: 14 MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV 73 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+ KE+D ++I +T+ YGKLDVLVNNAGIIETGTIE TSL QYDR+MNTN+R+IY+ Sbjct: 74 VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH 133 Query: 550 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 LTMLA P L+++KG GIRSFPGVLAYNISK VDQFTRCVAL LA KGVRV Sbjct: 134 LTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRV 192 >UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC79752 protein - Strongylocentrotus purpuratus Length = 303 Score = 159 bits (386), Expect = 7e-38 Identities = 78/183 (42%), Positives = 116/183 (63%), Gaps = 2/183 (1%) Frame = +1 Query: 184 SEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-- 357 ++++ + G ++ F S LGA+L L GR NL + C + + Sbjct: 45 AQLSQSATGAIINRWASSGIGAATSILF-SHLGARLVLAGRKEANLMRTKDSCMQTGNEE 103 Query: 358 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 537 L++T +L S + ++++ ++ YGKLD+LVNNAG+I G+IEN+SL YD +M+ NVR Sbjct: 104 ALTVTGELRDGSYRKHLVEQAMEEYGKLDILVNNAGVISLGSIENSSLEDYDTMMDVNVR 163 Query: 538 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 S+++LT LAVPHL+E+KG G+R+F GVL+Y +SKA++D FTRC AL LAPKG Sbjct: 164 SVFHLTSLAVPHLIETKGNIVNVSSVNGLRAFAGVLSYCMSKAALDHFTRCTALELAPKG 223 Query: 718 VRV 726 VRV Sbjct: 224 VRV 226 >UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p - Drosophila melanogaster (Fruit fly) Length = 255 Score = 142 bits (343), Expect = 1e-32 Identities = 71/177 (40%), Positives = 108/177 (61%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M+ + KVV L++ GA L+L GRNV NL+ K K + A Sbjct: 5 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSL-KGTQAEIVVA 63 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+TK++D I+++T+ +G++DVLVNNAGI+ G + + + ++D ++NTN+R + LT Sbjct: 64 DVTKDADA--IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLT 121 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +PHLL++KG GIR F G L+Y +SKA++DQFT+ VAL +AP+GVRV Sbjct: 122 KAVLPHLLKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRV 178 >UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3alpha-reductase - Spodoptera littoralis (Egyptian cotton leafworm) Length = 249 Score = 136 bits (329), Expect = 5e-31 Identities = 70/178 (39%), Positives = 105/178 (58%), Gaps = 3/178 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITAD 378 FA KVV K GA ++ GRN L++V C + A+ L+I AD Sbjct: 2 FANKVVLVTGGSSGIGAATVEAFVKEGASVAFVGRNQAKLKEVESRCQQHGANILAIKAD 61 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLT 555 ++K+ + + I+++T+D +GKLDVLVNNAGI+ +E T + +D MNTN+R + +T Sbjct: 62 VSKDEEAKIIVQQTVDKFGKLDVLVNNAGILRFASVLEPTLIQTFDETMNTNLRPVVLIT 121 Query: 556 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 LA+PHL+ +KG I PG+++Y++SKA++D FT+ AL LAP GVRV Sbjct: 122 SLAIPHLIATKGSIVNVSSILSTIVRIPGIMSYSVSKAAMDHFTKLAALELAPSGVRV 179 >UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 269 Score = 132 bits (318), Expect = 1e-29 Identities = 73/180 (40%), Positives = 101/180 (56%), Gaps = 5/180 (2%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 369 F GKVV + GA L+L GR+ L+K ++DC L+I Sbjct: 4 FVGKVVLITGASSGIGAETAVHFAAEGAGLALVGRDEGRLEKTAQDCMAKGLAKDKVLTI 63 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIY 546 AD+ E D+++I++ TI ++G+LDVLVNNAG + + + T + +D L+ NVRS+ Sbjct: 64 KADMCVEEDVKRIVESTITYFGRLDVLVNNAGQAKLDLLRSETVMENFDDLLKLNVRSVV 123 Query: 547 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 LT LAVPHL+ SKG G R +YNI +A+ DQFTRC A+ LAPKGVRV Sbjct: 124 QLTNLAVPHLITSKGSVVNVSSLAGKRVAHMSFSYNILRAATDQFTRCCAVDLAPKGVRV 183 >UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-like protein; n=3; Bilateria|Rep: U2 snRNP splicing factor small subunit-like protein - Schistosoma mansoni (Blood fluke) Length = 265 Score = 129 bits (312), Expect = 6e-29 Identities = 72/187 (38%), Positives = 104/187 (55%), Gaps = 10/187 (5%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----- 360 ++ + KV +KLGA ++L R+ L++ + C + + Sbjct: 2 ISLSRKVAIITGASSGIGRATAILFAKLGACVALIARDKSRLEETRQACIQISHPDVYEK 61 Query: 361 -----LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 525 L I ADL + +IEK + I+H+ +LD+LVNNAG + T E+ ++A+Y+ LM Sbjct: 62 HKEPFLCIEADLAETCEIEKAYRLAINHFHQLDILVNNAGCMIRDTAESFNVAEYEHLMK 121 Query: 526 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXL 705 NV + LT LA+P L SKG G RSFPGV++Y ISKA++DQFTRC AL L Sbjct: 122 VNVTAAITLTNLAIPDLAASKGSIVNVSSVCGKRSFPGVMSYCISKAALDQFTRCTALDL 181 Query: 706 APKGVRV 726 APKG+RV Sbjct: 182 APKGIRV 188 >UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP00000021339; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000021339 - Strongylocentrotus purpuratus Length = 242 Score = 125 bits (301), Expect = 1e-27 Identities = 62/156 (39%), Positives = 95/156 (60%), Gaps = 4/156 (2%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSITADLTKESDIEKIIKKTIDHYGK 438 + LG +L+LTGRN+E LQ+V+ +C + L I AD E+D+++ ++TI + + Sbjct: 6 ASLGCRLALTGRNMETLQEVTNECIRRGLDKNKILMIQADFELEADVKRTAEETIQKFNQ 65 Query: 439 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 618 +DVLVNNAG++ G++E SL +D++ NVR+ LT L P L+++KG Sbjct: 66 IDVLVNNAGVLTAGSVETVSLESFDKIFAVNVRAPLQLTQLLAPQLIKTKGTVVNVSSVV 125 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G S P L Y++SK ++D TR +A LAP GVRV Sbjct: 126 GKVSMPDFLIYSMSKTALDHMTRSIAEELAPHGVRV 161 >UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 250 Score = 121 bits (291), Expect = 2e-26 Identities = 65/177 (36%), Positives = 98/177 (55%), Gaps = 4/177 (2%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSITA 375 GKV +++G +L+LTGR+ E L+ V K C + + L I A Sbjct: 3 GKVALITGSSSGIGAGIAERFAEIGCRLALTGRDAEKLKDVGKSCCERGLSEKEILVIAA 62 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 DLT++ D+E+I KTI+ +G+LD+L+NNAG G + + +D +M N+RS YL+ Sbjct: 63 DLTEDEDLERIFSKTIEKFGRLDILINNAGRPAKGRFHDLQMTFFDDVMRLNLRSAIYLS 122 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 LA+P+L ESKG + Y+ISK ++DQFT+ +A+ L P GVRV Sbjct: 123 KLAIPYLKESKGCVVNMSSVASKTTCDYNPTYSISKVALDQFTKSLAVELGPYGVRV 179 >UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Sphingobacteriales|Rep: Short-chain dehydrogenase/reductase SDR - Microscilla marina ATCC 23134 Length = 273 Score = 104 bits (250), Expect = 2e-21 Identities = 57/155 (36%), Positives = 83/155 (53%), Gaps = 1/155 (0%) Frame = +1 Query: 274 KLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 450 K GA++ +TGRN E L KVS + + L I AD + ESD + ++K+TID YGK+DVL Sbjct: 30 KAGAKVVITGRNNEKLVKVSDMLNIEQIDNLPIVADSSVESDCKMVVKETIDKYGKIDVL 89 Query: 451 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 630 +NNAGI L+ +R+M N Y+T A+P+L +++G G R Sbjct: 90 INNAGISMRAMFAELDLSVIERVMQINFFGTVYITKFALPYLTQTQGSIVGVSSIAGFRG 149 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 PG Y+ SK ++ F + L K V V V+ Sbjct: 150 LPGRTGYSASKFAMQGFLESLRTELLKKNVNVLVA 184 >UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14; n=5; Caenorhabditis|Rep: Dehydrogenases, short chain protein 14 - Caenorhabditis elegans Length = 279 Score = 103 bits (246), Expect = 6e-21 Identities = 61/184 (33%), Positives = 99/184 (53%), Gaps = 9/184 (4%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 369 F+GKV L++ GA++++TGRN + L++ ++ K LSI Sbjct: 4 FSGKVALVTGSSNGIGRATAVLLAQEGAKVTITGRNADRLEETRQEILKSGVPEDHVLSI 63 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTI-ENTSLAQYDRLMNTNVR 537 DL E ++++ TI +G+LD+LVNNAG + G + + ++ YDR+M N+R Sbjct: 64 ATDLATEKGQDELVNSTIQKFGRLDILVNNAGAAFNDDQGRVGVDQDVSVYDRIMQINMR 123 Query: 538 SIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 S+ LT A HL+++KG G ++ P + Y +SKA++DQ+TR A+ L Sbjct: 124 SVVTLTQKAKEHLVKAKGEVVNVSSIGAGPQAQPTFMYYAMSKAALDQYTRSAAIDLIQY 183 Query: 715 GVRV 726 GVRV Sbjct: 184 GVRV 187 >UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Pasteurellaceae|Rep: Short-chain dehydrogenase/reductase SDR - Actinobacillus succinogenes 130Z Length = 248 Score = 95.5 bits (227), Expect = 1e-18 Identities = 54/153 (35%), Positives = 82/153 (53%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 ++K GA + + GRN L++ ++ + + AD+ K DI +++ + + +GKLD+ Sbjct: 26 MAKDGANVVIIGRNEATLEE---SAEQHENITYLVADVLKSEDIARVLTEIQEEFGKLDI 82 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 627 +VNNAGI IEN +LA +DR NVR++ +T A+P+L SKG Sbjct: 83 VVNNAGIAPMTPIENINLADFDRTFALNVRAVIDVTAQAIPYLKASKGNIVNIISGLVHN 142 Query: 628 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PG Y SKA+V TR A LA G+RV Sbjct: 143 PMPGNCIYTASKAAVLSLTRTWAKELAAYGIRV 175 >UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; Frankia|Rep: Putative dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 295 Score = 94.7 bits (225), Expect = 2e-18 Identities = 47/151 (31%), Positives = 80/151 (52%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++++ GR+ + V + + I AD+T ++ +I+ T+DH+G LD+L Sbjct: 75 GARVAVVGRDKAKMDAVVESLAPLGEIIGIQADVTVVAEAARIVSATVDHFGGLDILATV 134 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSF 633 AG+ E + + + A YD + NV+ Y+ A HL++ +G G+R+F Sbjct: 135 AGVFEGAPLLDATEADYDIQFDLNVKGTYFCAQAAARHLVDQGRRGKIITVGSVAGLRAF 194 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PGV Y +KA+V T+ +A LAP G+ V Sbjct: 195 PGVSVYGATKAAVGFLTQVLAGELAPHGINV 225 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 94.7 bits (225), Expect = 2e-18 Identities = 58/184 (31%), Positives = 93/184 (50%), Gaps = 9/184 (4%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC----DKFASTLSI 369 F KV L+ GA++++TGRN E L++ + L + Sbjct: 4 FTDKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGNVLVV 63 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI----IETGTIENTSLAQYDRLMNTNVR 537 D+T+ES E +IK T+D +GK+D+LVNNAG + + N S+ Y + NV+ Sbjct: 64 VGDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQ 123 Query: 538 SIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 S+ +T A PHL +++G G + Y+I+KA++DQ+TR A+ L P+ Sbjct: 124 SVIEMTQKARPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAAIDLVPE 183 Query: 715 GVRV 726 G+RV Sbjct: 184 GIRV 187 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 94.3 bits (224), Expect = 3e-18 Identities = 50/180 (27%), Positives = 98/180 (54%), Gaps = 3/180 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 ++ +GKV LS+ GA +++TG+ E L+KVS + +++ +I A Sbjct: 23 LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEKVSSE---ISNSFAIVA 79 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+ K D++ IKK ++ +G+LD+LVNNAG+ + + +++ +++ N+ + + Sbjct: 80 DVRKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRV 139 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALXLAPKGVRV 726 T A+PHL ++ G G++++ G AY+ +KA++ T+C AL + +RV Sbjct: 140 TKEAIPHLQKTSGSIINISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRV 199 >UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella sediminis HAW-EB3|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sediminis HAW-EB3 Length = 245 Score = 93.9 bits (223), Expect = 4e-18 Identities = 57/176 (32%), Positives = 82/176 (46%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 378 NF KVV GA + +TGR L++ S++ I D Sbjct: 3 NFENKVVLITGGGTGIGKATASAFIAKGATVVITGRRQSVLEETSQELGP--QVYPIVGD 60 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 ++K+ +I+++TI +G+LDVLVNNAG + G + TS + + TNV ++ L Sbjct: 61 VSKKGGPARIVEETISKFGRLDVLVNNAGTGKMGPLSETSDEDIESIYRTNVFALLALVR 120 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A HL SKG P V AY SKA+V+ TR +A L P G+RV Sbjct: 121 EATVHLANSKGAVVNISSVAAQGMMPAVAAYASSKAAVEHATRLLAAELGPMGIRV 176 >UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 402 Score = 93.1 bits (221), Expect = 6e-18 Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 9/184 (4%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL----QKVSKDCDKFASTLSI 369 F+GKV ++ GA++++TGRN E L Q + K + L+I Sbjct: 126 FSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEETRQAILKSGVPAENVLAI 185 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ----YDRLMNTNVR 537 ADL + +I T+ +G+LD+LVNNAG + Q +D+ N+R Sbjct: 186 AADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGIDQQIEDFDKTFQINMR 245 Query: 538 SIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 S+ L A HL+++KG G + P ++ Y +SKA++DQFTR A+ L Sbjct: 246 SVVTLVQKAKEHLIKTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLIQH 305 Query: 715 GVRV 726 GVRV Sbjct: 306 GVRV 309 Score = 34.7 bits (76), Expect = 2.4 Identities = 15/29 (51%), Positives = 21/29 (72%) Frame = +1 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRV 726 ++ Y +SKA++DQFTR A+ L GVRV Sbjct: 1 MMYYGMSKAALDQFTRSTAITLIQHGVRV 29 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 92.7 bits (220), Expect = 9e-18 Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 M F GKV L++ GA + + R+ + + + + L++ Sbjct: 1 MEFQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVI 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 AD++ ESD +I T+ +G +D+LVNNAGI + GTIE+T+L + ++N N+ ++ + Sbjct: 61 ADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVFLV 120 Query: 553 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + +P L G G+R+ G AY SK V TR +AL AP G+RV Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRV 179 >UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketoreductase - Symbiobacterium thermophilum Length = 241 Score = 91.9 bits (218), Expect = 2e-17 Identities = 52/152 (34%), Positives = 80/152 (52%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 450 ++ GA++ +TGR E L++ +TAD+T SD +++++ +G++DV+ Sbjct: 19 ARRGAKVLITGRRPEPLRETEAAAPGIRG---VTADVTVASDARRVVEEAAKLWGRIDVV 75 Query: 451 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 630 VNNAG+ +G E +L TNV L A+P L ES+G G ++ Sbjct: 76 VNNAGMFASGPFEKVGAETAAQLFATNVFGPINLVREALPWLKESRGAIINVSSTYGHKA 135 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 V Y SKA++D TRC AL LAP G+RV Sbjct: 136 AANVAHYAASKAALDHLTRCWALELAPYGIRV 167 >UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; Sarcoptes scabiei type suis|Rep: Putative uncharacterized protein - Sarcoptes scabiei type suis Length = 304 Score = 91.9 bits (218), Expect = 2e-17 Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 7/183 (3%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS----TLS 366 +F+GKV ++ GA++ +TGR+ L+KV+ + +K L Sbjct: 38 DFSGKVALVTGSSSGIGAAIALQFAQYGAKVCITGRDSNALEKVAGEIEKATGGKHRPLK 97 Query: 367 ITADLTKESDIE-KIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQ-YDRLMNTNVR 537 I L ++ + ++I +T++ +G+LD LVNNAG G + + +L YD++ + NVR Sbjct: 98 IIGGLVEDRQLPVRLINETVNEFGRLDFLVNNAGGSTAHGKLTDENLMDSYDKVFDLNVR 157 Query: 538 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 S+ +L +A PHL ++KG I P L Y+ SKA++D T+C+A+ G Sbjct: 158 SVLHLCQVAKPHLEKTKGNIINISSIAAI--VPYSLIYSPSKAALDMMTKCLAIEYGDIG 215 Query: 718 VRV 726 VRV Sbjct: 216 VRV 218 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 91.1 bits (216), Expect = 3e-17 Identities = 50/122 (40%), Positives = 69/122 (56%) Frame = +1 Query: 358 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 537 TL + AD+ IE II ++++ G LDVLVNNAGI TG TS + +M NV Sbjct: 60 TLKV-ADVGDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVD 118 Query: 538 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 ++Y T A+PHL++S+G GI + AY+ SK +V FTR VA+ A +G Sbjct: 119 GLFYATRAALPHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVAVDYAQRG 178 Query: 718 VR 723 VR Sbjct: 179 VR 180 >UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; Rhizobium sp. NGR234|Rep: Putative uncharacterized protein - Rhizobium sp. (strain NGR234) Length = 244 Score = 89.4 bits (212), Expect = 8e-17 Identities = 46/122 (37%), Positives = 73/122 (59%), Gaps = 1/122 (0%) Frame = +1 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 SI+ D+T E + + I K + G+LD+L+NNAG+ E+G++E TSL Q+ RL++TN+ SI Sbjct: 49 SISLDVTDEGNWTRAISKVVSAAGRLDILINNAGVRESGSVEETSLEQWRRLIDTNLTSI 108 Query: 544 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 + AVP + ++ G GIR ++AY+ SK+ + T +AL LA + Sbjct: 109 FLGCRAAVPAIRQAGGGAIVNVGSITGIRGTENMVAYSASKSGITSMTSSLALDLASDNI 168 Query: 721 RV 726 RV Sbjct: 169 RV 170 >UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; Methanosarcina|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Methanosarcina acetivorans Length = 242 Score = 89.4 bits (212), Expect = 8e-17 Identities = 47/149 (31%), Positives = 80/149 (53%), Gaps = 3/149 (2%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDC--DKFASTLSITADLTKESDIEKIIKKTIDHYGKL 441 L+K G + + RN E+ K ++D D + I D+ E D+ ++I +TID G+L Sbjct: 31 LAKEGVNIIIAARN-ESESKETQDQLKDMGSKAFEIPVDVRNEEDVRRLISRTIDKCGRL 89 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 618 D+L+NNAG+ +E T++ +YD++++TN++ ++ T A+P+L SK G Sbjct: 90 DILINNAGVALKKRLEETTVEEYDKIIDTNLKGVFLCTKYAIPYLRRSKNGKIINISSIG 149 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXL 705 G+ P Y SK V+ T +A L Sbjct: 150 GLHGIPEFSVYCASKFGVNGVTEAIAAEL 178 >UniRef50_A2TF13 Cluster: 11-beta short-chain dehydrogenase reductase; n=3; Brassicaceae|Rep: 11-beta short-chain dehydrogenase reductase - Brassica napus (Rape) Length = 238 Score = 89.0 bits (211), Expect = 1e-16 Identities = 55/156 (35%), Positives = 82/156 (52%), Gaps = 3/156 (1%) Frame = +1 Query: 283 AQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 A L+L R + LQ V+ K +S + I D+TK +D K I +TI H+GK+D L+N Sbjct: 1 ADLALVARREDRLQIVADTSRKLSSRDVIIIPGDVTKINDCMKFISETISHFGKVDHLIN 60 Query: 457 NAGIIETGTIENTSLAQ-YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 633 NAG+ T EN S Q + +M+TN Y+T A+PHL +SKG + Sbjct: 61 NAGVSRTVLFENFSQIQDANPIMDTNFWGSTYITYYAIPHLRKSKGKIVVIASAAAKIAI 120 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRVTVSIL 741 P Y+ SKA++ F + + L P ++VT+ L Sbjct: 121 PVATIYSASKAALLGFYEALRIELNP-DIKVTIVFL 155 >UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 283 Score = 89.0 bits (211), Expect = 1e-16 Identities = 54/189 (28%), Positives = 93/189 (49%), Gaps = 6/189 (3%) Frame = +1 Query: 178 KYSEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS 357 +Y + GKVV ++G+++ + R+ + +Q V K + + S Sbjct: 6 QYKAAFPDLKGKVVIVTGSTRGIGYEIVKLFKEMGSRVVVNARSADEVQTVVKKLNDYVS 65 Query: 358 ---TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNT 528 + + D++K D EKI+ +T+D YGK+DVLVNNAGI N S+ ++R + Sbjct: 66 DGEAIGVAGDVSKYEDCEKIVNETVDKYGKIDVLVNNAGINMIRDSLNLSIDDWERTLRI 125 Query: 529 NVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVAL 699 ++ S +Y++ L ++ + KG G I + P AY +KA + TR +A+ Sbjct: 126 DLFSAFYMSQLVARTMVAKKVKGSIVNIASMVGPIVALPKRAAYAAAKAGLVGLTRVLAV 185 Query: 700 XLAPKGVRV 726 AP G+RV Sbjct: 186 EWAPLGIRV 194 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 89.0 bits (211), Expect = 1e-16 Identities = 54/179 (30%), Positives = 89/179 (49%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 372 MNF GKVV ++ GA++++ + E ++ + + I Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+ K D E+I+KKT++ +G+LD+LVNNAGI+ G IE TS +D+ M NV+ + L Sbjct: 61 GDVAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118 Query: 553 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + AV + + G G+ P Y++SKA++ TR +A+ G+RV Sbjct: 119 SKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRV 177 >UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1; Thermobifida fusca YX|Rep: Short-chain alcohol dehydrogenase - Thermobifida fusca (strain YX) Length = 267 Score = 88.6 bits (210), Expect = 1e-16 Identities = 43/151 (28%), Positives = 80/151 (52%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA + RN + + D T L++TAD++ +D E++ T++H+G++D++ Sbjct: 33 GASVVCVDRNADAAHSAADDIAAAGGTALALTADVSSAADAERMTTTTLEHFGRIDIVFA 92 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 633 NAGI +G T+ ++DR++ N++ ++ + A+PH++E + G G+ Sbjct: 93 NAGIPGSGDAHTTTEEEWDRVIAINLKGVWLTSKYALPHMVERRSGVITNQASVGGLIGI 152 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PG+ Y +K V TR +A AP +RV Sbjct: 153 PGIFPYAAAKGGVISMTRQMAAAYAPHNIRV 183 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 88.2 bits (209), Expect = 2e-16 Identities = 47/149 (31%), Positives = 75/149 (50%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA + L GR L +V + + AD+T +D+E ++ + +G++D+LVNN Sbjct: 31 GAIVVLNGRRESKLAEVGAELGTDRCMIR-PADVTIAADVESLVADAVRRFGRIDILVNN 89 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AG + + Q+ L NV + Y+T A+PHL+ES G G+ G Sbjct: 90 AGTGALIDFLGSPIQQWRDLFAVNVDGVLYMTRAALPHLIESGGSIVNVSSLSGLGGDRG 149 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRV 726 + YN +K +V TR +AL P+GVR+ Sbjct: 150 LSFYNATKGAVSNLTRSLALEFGPRGVRI 178 >UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; n=4; Xanthobacter autotrophicus Py2|Rep: 2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp. (strain Py2) Length = 250 Score = 87.8 bits (208), Expect = 2e-16 Identities = 47/125 (37%), Positives = 68/125 (54%), Gaps = 4/125 (3%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 531 L + AD+ E D+ I T++ +G +DVLVNNAGI E G + T + Q+D++M N Sbjct: 55 LRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114 Query: 532 VRSIYYLTMLAVPH-LLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 708 VR I+ +PH LL+ G + +FPG AY SK +V Q T+ VA+ A Sbjct: 115 VRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYA 174 Query: 709 PKGVR 723 G+R Sbjct: 175 GSGIR 179 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 87.0 bits (206), Expect = 4e-16 Identities = 53/179 (29%), Positives = 82/179 (45%), Gaps = 4/179 (2%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 381 FAGK V GA + + RN E KV+ D TL+ D+ Sbjct: 7 FAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDA-DRTLTCPGDV 65 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 + +I+ KT++ +G LD LVNNAG+ + + T + DR+++ NV+ + YL Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIYLCRA 125 Query: 562 AVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+PHL +S+ G GI + YN SK ++ TR +A + G+RV Sbjct: 126 AIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRV 184 >UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15; n=4; Caenorhabditis|Rep: Dehydrogenases, short chain protein 15 - Caenorhabditis elegans Length = 278 Score = 87.0 bits (206), Expect = 4e-16 Identities = 55/184 (29%), Positives = 89/184 (48%), Gaps = 9/184 (4%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS----I 369 F+ KV L++ GA++++TGR+ E +Q+ + K + + Sbjct: 4 FSDKVAIITGSSSGIGRSTAVLLAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIV 63 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTI-ENTSLAQYDRLMNTNVR 537 DL + +++IK T+ +GK+D+L+NNAG +G I ++ +D +M N+R Sbjct: 64 LGDLNESECQDELIKSTLSRFGKIDILINNAGAAFADPSGKIGSEAAIGIFDDMMKLNLR 123 Query: 538 SIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 S+ L PHL+ SKG G + + Y I KA +DQ TR +AL L P Sbjct: 124 SVVELVKKCRPHLIASKGEIVNVSSIAAGPQPYIYYTYYGICKAGLDQLTRSLALELIPF 183 Query: 715 GVRV 726 VRV Sbjct: 184 DVRV 187 >UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium beijerinckii NCIMB 8052 Length = 246 Score = 86.6 bits (205), Expect = 6e-16 Identities = 49/178 (27%), Positives = 86/178 (48%), Gaps = 2/178 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSIT 372 N GKV LS LGA++ + N ++V ++ K ++I Sbjct: 3 NLEGKVAIITGASRGIGSAIARQLSALGAKVVVNYSNNAVKAEEVVEEITKSGEQAVAIK 62 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 AD++ D+EK+ +TI +G++D+L+NNAG+I + + + ++D+L N NV+ Y+ Sbjct: 63 ADVSNIKDVEKLFSETITKFGRVDILINNAGVILYKLLSDVTEEEFDKLFNINVKGTYFA 122 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+ H +E+ G FP Y +K +V+Q TR +A PK + + Sbjct: 123 CQQAMKH-MENNGRIINFSTSVVGSMFPTYSVYAATKGAVEQITRQLAKEFGPKKITI 179 >UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR; n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 251 Score = 86.6 bits (205), Expect = 6e-16 Identities = 51/151 (33%), Positives = 76/151 (50%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLV 453 GA ++ T G +V + KV D + L I AD + I + +T+ G LD+LV Sbjct: 35 GAAVAFTYGSSVSDADKVVVDVSRGGGRVLPIRADSSDAGQIASAVDETVTRLGGLDILV 94 Query: 454 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 633 NNAG+ G +E+ L Q+DRL+ NVR ++ AVPHL + Sbjct: 95 NNAGVAHLGAVESFPLDQFDRLVAVNVRGVFVAIQCAVPHLGDGGRIINIGSVNADRVPS 154 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PG+ Y ++KA+V TR +A L P+G+ V Sbjct: 155 PGLSVYAMTKAAVAGLTRGLARELGPRGITV 185 >UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=1; Neosartorya fischeri NRRL 181|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 255 Score = 86.2 bits (204), Expect = 7e-16 Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 5/181 (2%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSIT- 372 + AG+V L+KLGA L+L+ NVE LQK +C ++ S +++T Sbjct: 4 SIAGRVYTVTGASSGIGQATAVKLAKLGAAGLALSDVNVEGLQKTKDECSRYESNVTVTR 63 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIENTSLAQYDRLMNTNVRSI 543 D+++ + + +T+ +G+LD N AGI T E S +DRLM+ N++ + Sbjct: 64 VDVSRNDQVTRWASETVQQFGRLDGAANIAGIAMGDGTTNCETISPESWDRLMDVNLKGV 123 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +PHL G G+R P AY+ SK V + A P G+R Sbjct: 124 MLCMRAQLPHLPRPGGVIVNVSSTSGLRGLPHNAAYSSSKFGVIGLSASAAGEFGPLGIR 183 Query: 724 V 726 + Sbjct: 184 I 184 >UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Pedobacter sp. BAL39|Rep: Short-chain dehydrogenase/reductase SDR - Pedobacter sp. BAL39 Length = 250 Score = 85.8 bits (203), Expect = 1e-15 Identities = 45/152 (29%), Positives = 83/152 (54%), Gaps = 1/152 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA ++ GRN E L++ + D F ++I D+T D+E++++ T + +GK+D+LV Sbjct: 30 GASGAIVGRNQETLKRAASQLGDGF---IAINGDVTNPGDLERMMRNTSEQFGKIDILVA 86 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 636 NAG TGT+ + S + YD+ M+ N++S+Y+ A+P++ + R++P Sbjct: 87 NAGAGTTGTVADISESDYDKTMDLNLKSVYFTVQKALPYMADGSSIILIGSNAAH-RAYP 145 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 Y +KA+V + + L + +RV V Sbjct: 146 SFGLYGAAKAAVIFLAKSFSNDLLDRKIRVNV 177 >UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 85.8 bits (203), Expect = 1e-15 Identities = 57/188 (30%), Positives = 93/188 (49%), Gaps = 13/188 (6%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSI 369 F+GKVV + GA++ L GR+ ++++K K C + + L Sbjct: 6 FSGKVVLISGSSKGIGQATAVKFAAEGAKIVLNGRSADDVEKTRKLCMEVGAKPWDLLPT 65 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIE-NTSLAQYDRLMNTNVR 537 D+T E ++ ++ I ++GKLD+L+NNAG +E TG + DR N+N + Sbjct: 66 VGDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWNSNFK 125 Query: 538 SIYYLTMLAVPHLLESKG-----XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX 702 S+ LT A+PHL+++KG G+ S P Y + KA++DQ +R +A Sbjct: 126 SVLMLTQAAMPHLIKTKGDIVNVSTFLSSGPIGVMSMP---YYAVPKAALDQMSRSMAHE 182 Query: 703 LAPKGVRV 726 KGVR+ Sbjct: 183 YMLKGVRL 190 >UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 255 Score = 85.4 bits (202), Expect = 1e-15 Identities = 47/155 (30%), Positives = 82/155 (52%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L++ GA L L RN ++ KV+ + K L++ D+ K DI+ ++ K I +G +D Sbjct: 30 LAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKTDMLKADDIQAMVDKGIAQFGTID 89 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 +LVNNAGI N + +D +++TN++ + + + ++++K G G Sbjct: 90 ILVNNAGINLVKPFVNLTEEDWDSVVDTNLKGYFLCSQVVGREMIKNKNGCVINNASVFG 149 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +R FP + +Y SK V Q TR +A+ A +RV Sbjct: 150 LRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRV 184 >UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia phymatum STM815 Length = 257 Score = 85.4 bits (202), Expect = 1e-15 Identities = 51/181 (28%), Positives = 85/181 (46%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M+FA K L GA++++TGR+ + L + + + S L I A Sbjct: 1 MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGP--SALPIRA 58 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+ + I+ ++K D +GKLD++ NAG+ + T+ +++ +M TNV S++ Sbjct: 59 DINDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTV 118 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 AVP L+ G PG AY+ SKA++ R +A L +G+RV Sbjct: 119 QAAVP-LMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTV 177 Query: 736 I 738 I Sbjct: 178 I 178 >UniRef50_A7QUU9 Cluster: Chromosome chr1 scaffold_180, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_180, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 331 Score = 85.4 bits (202), Expect = 1e-15 Identities = 68/221 (30%), Positives = 101/221 (45%), Gaps = 4/221 (1%) Frame = +1 Query: 91 SLNYIIT-L**AYSCLFYSQQEVFNTVSH*KYSEVTMNFAGKVVXXXXXXXXXXXXXXXF 267 ++N ++T L A CL +F V + N A KVV Sbjct: 10 AINLVLTPLVFAIICLILPFLIIFRLVVSISSRFSSENMARKVVLITGASSGIGEHMAYE 69 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKL 441 +K+GA L+L R E L+ V+ S L++ AD++ +D ++ I TI+H+GKL Sbjct: 70 YAKMGACLALVARRKEKLEAVAARARGLGSPDVLALRADVSNVNDCKRSIDDTINHFGKL 129 Query: 442 DVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 618 + LVNNAGI +E T + LM+ N Y T A+PHL ++KG Sbjct: 130 NHLVNNAGIGSVCALEEITDITNSGSLMDVNYWGSVYPTYFAIPHLRKTKGKIVVNSSTS 189 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVSIL 741 + P + Y SKA+V F + L P+ VTVSI+ Sbjct: 190 ALVQPPSMSFYTSSKAAVIGFFESLRGELDPE---VTVSIV 227 >UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bacteroidetes|Rep: Short chain dehydrogenase - Algoriphagus sp. PR1 Length = 252 Score = 85.0 bits (201), Expect = 2e-15 Identities = 50/179 (27%), Positives = 87/179 (48%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 M GK S+ GA L L+GRN EN ++ + ++ + + Sbjct: 1 MRLKGKTAIITGATSGMGKAIAKRFSEEGAFLILSGRNQENGIELERSLNEAGGKAVFVK 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+ E ++K I ++GKLD++V NAG + G++ SLA++ MNTN ++++L Sbjct: 61 GDVGIIETNEALVKAAISNFGKLDIVVTNAGKLGLGSVTEISLAEWQETMNTNFNAVFFL 120 Query: 553 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + A+P +++S G +SFP AY SKA++ + +A+ P +RV Sbjct: 121 SRFAIPEMIKSGGGTILANSSIAAFKSFPNHAAYCASKAALVALVKEMAVDYGP-NIRV 178 >UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; Zymomonas mobilis|Rep: Putative uncharacterized protein - Zymomonas mobilis Length = 254 Score = 84.6 bits (200), Expect = 2e-15 Identities = 50/185 (27%), Positives = 94/185 (50%), Gaps = 4/185 (2%) Frame = +1 Query: 190 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLS 366 V+ +++GKV +K A +++ GR+ N+Q+ + + ++ Sbjct: 3 VSFDYSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIA 62 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSL--AQYDRLMNTNVRS 540 I AD+++E I+ I+KT++ +GKLD NNAG IE I + ++DR+++TN+ Sbjct: 63 IQADVSQEDSIKAAIEKTVETFGKLDFAFNNAG-IEHKAIPAADIPSEEWDRIISTNLNG 121 Query: 541 IYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 +++ +P +L+S G G++ FPG AY SK + ++ AL A + Sbjct: 122 VFFSMKHEIPAMLKSGSGSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAALDYAKQH 181 Query: 718 VRVTV 732 +R+ V Sbjct: 182 LRINV 186 >UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 253 Score = 84.6 bits (200), Expect = 2e-15 Identities = 48/178 (26%), Positives = 84/178 (47%) Frame = +1 Query: 190 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI 369 ++ F GKV L + GA + ++GR + L V+ S + + Sbjct: 1 MSKRFDGKVAIVTGGGSGIGAAIANRLLEEGASVMMSGRTEKRLSDVASKMPADRSGIFV 60 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 A+++ D + ++ T++ +G++D +VN AG+ GTI+ TS +D + +++ ++Y Sbjct: 61 -ANVSSRPDCDALVAATVERFGRIDTVVNAAGMNFVGTIQETSDQDWDECIASDLSGVFY 119 Query: 550 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 ++ AVPHL E+KG + AYN +K V TR A L GVR Sbjct: 120 MSRAAVPHLKETKGSIVNIGSVSSLGGGWSHAAYNAAKGGVANLTRSAACDLGKFGVR 177 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 84.6 bits (200), Expect = 2e-15 Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 3/176 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSI 369 M+ GK + L+K G + LT R E L+++ DK L I Sbjct: 1 MSMKGKTIIITGASSGIGEATAMRLAKEGVNVVLTARREEKLKELKSKIDKENGGKALVI 60 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+TK+ D + +I KT +G +D L+NNAG++ ++N ++D++++ N++ + Sbjct: 61 PGDVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLN 120 Query: 550 LTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 +P ++E K G + +PG Y +K++V F+ + LAPK Sbjct: 121 GVAAVLPTMMEQKSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGLRQELAPK 176 >UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reductase; n=5; Pezizomycotina|Rep: 1,3,6,8-tetrahydroxynaphthalene reductase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 276 Score = 84.6 bits (200), Expect = 2e-15 Identities = 49/176 (27%), Positives = 88/176 (50%), Gaps = 2/176 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITAD 378 +GKV L++ GA +++ G + ++ Q+V + S ++I AD Sbjct: 11 SGKVALVTGGGRGIGAGIALELARRGASVAINYGHSAKSAQEVVEAIQAIGSQAVAIKAD 70 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 LT +IE +IK+ + H+G+LD++V+N+G+ + +E T+L ++ + N N R+ ++ Sbjct: 71 LTCVPNIESLIKQVVSHFGRLDIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQMFVAR 130 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A H+ G+ PG Y SKA+++ FTRC+A KG V Sbjct: 131 YAYDHIQPGGRVILMSSIAAGL-GVPGHALYAGSKAAIEGFTRCLAADFGRKGCTV 185 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 84.2 bits (199), Expect = 3e-15 Identities = 47/189 (24%), Positives = 90/189 (47%), Gaps = 3/189 (1%) Frame = +1 Query: 169 SH*KYSEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD- 345 +H + + G+V L+K GA++ L R+ +++++++ + Sbjct: 10 AHPERKRYMFDLTGQVALVTGASRGIGEAAARSLAKYGAKVVLAARSDKDIERIAGEIRA 69 Query: 346 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLM 522 + ++ D+ D+ K ++ +D YG LD+LVNNAG+IE IE++ A++ +++ Sbjct: 70 EGQDATAVVCDVADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVI 129 Query: 523 NTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 699 + NV+ +YY A H+L + G + + G Y SKA+ TRC Sbjct: 130 DINVKGVYYGLHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK 189 Query: 700 XLAPKGVRV 726 KG+R+ Sbjct: 190 EFGDKGLRI 198 >UniRef50_Q9LUF2 Cluster: 11-beta-hydroxysteroid dehydrogenase-like; n=2; Arabidopsis thaliana|Rep: 11-beta-hydroxysteroid dehydrogenase-like - Arabidopsis thaliana (Mouse-ear cress) Length = 303 Score = 84.2 bits (199), Expect = 3e-15 Identities = 55/178 (30%), Positives = 85/178 (47%), Gaps = 3/178 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADL 381 GKVV ++ GA L+L R + LQ V+ C K S + D+ Sbjct: 47 GKVVIITGSSSGIGEHLAYEYARRGAYLTLVARREDRLQVVADRCRKLGSPDVAVVRGDV 106 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTS-LAQYDRLMNTNVRSIYYLTM 558 + D ++ +++TI +G+LD LVNNAGI E E+ S ++ ++NTN Y T Sbjct: 107 SVIKDCKRFVQETISRFGRLDHLVNNAGIAEAKFFEDYSEISDVLPIVNTNFWGPVYATH 166 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 A+PHL ++KG G P + Y SKA++ F + + L P+ V VT+ Sbjct: 167 FAIPHLKKTKGKIIAVASPAGWSGVPRMSIYAASKAAMINFYETLRIELHPE-VGVTI 223 >UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succiniciproducens MBEL55E|Rep: FabG protein - Mannheimia succiniciproducens (strain MBEL55E) Length = 248 Score = 83.8 bits (198), Expect = 4e-15 Identities = 48/153 (31%), Positives = 79/153 (51%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 L++ GA++ + GR + LQ+ + A + AD+ K+ D++KI+++ YG LD+ Sbjct: 26 LAQEGAKVLVVGRTEKTLQETTALHPNIAYAV---ADIEKDDDVQKIVQQLNQKYGGLDI 82 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 627 L+NNAG I + +YD++ NVR++ LT+ +P L KG Sbjct: 83 LINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLTLQCLPMLKARKGNIINMSSAICRN 142 Query: 628 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P + Y +KA+V+ FT+ A L GVRV Sbjct: 143 HLPNMSMYAGTKAAVEIFTKIWAKELGADGVRV 175 >UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 281 Score = 83.4 bits (197), Expect = 5e-15 Identities = 45/151 (29%), Positives = 79/151 (52%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ +TGRN E L +K+ A L++ AD T + E I++ + +GK D++ N Sbjct: 53 GAKVVITGRNKETLAAAAKELGPNA--LAVVADATDIAATEAAIRQGAEKFGKFDIVFAN 110 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AGI + + +L ++++++TN+ +++ A+PH L + PG Sbjct: 111 AGIPGSTPLGAATLEVFEKVISTNLTGVFFTVQSALPH-LNDNASIILNGSVISVLGIPG 169 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 AY +KA V R +A L+P+G+RV V Sbjct: 170 YSAYGAAKAGVRAMARIMASELSPRGIRVNV 200 >UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR precursor - Solibacter usitatus (strain Ellin6076) Length = 346 Score = 83.4 bits (197), Expect = 5e-15 Identities = 46/179 (25%), Positives = 86/179 (48%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD-CDKFASTLSIT 372 M+ GKVV ++ GA+++L R+ E L++ +D + A + T Sbjct: 29 MDMRGKVVLITGGSHGLGLALARRFAQEGAKIALCARSEEELRRAREDVASRGAEVFTAT 88 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D++ +E ++ T+D + ++DVLVNNAGII G ++ ++ +++ M Y Sbjct: 89 CDVSDRLQVEAVVTATLDRFRRIDVLVNNAGIIHVGPVDAMTIEDFEQAMGVMFWGTVYA 148 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 TM +PH+ + G + S P +L Y+ +K + F+ + L+ GV+V Sbjct: 149 TMAVLPHMRGRRDQRIVNITSIGAKVSVPHLLPYSCAKFAAAAFSEGMRAELSGTGVKV 207 >UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep: Oxidoreductase - Streptomyces echinatus Length = 295 Score = 83.4 bits (197), Expect = 5e-15 Identities = 46/151 (30%), Positives = 81/151 (53%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ + GR L++ ++ ++ AD+T + ++ ++ +G++DVLVNN Sbjct: 74 GARVLVVGRTPGTLEETARH---HPGIRALPADITAPDGPDTVVSAALERFGRIDVLVNN 130 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGX--XXXXXXXXGIRSF 633 A + GT++ A D + TN+R+ LT A+P L +S G G R++ Sbjct: 131 AALGIAGTLDTLDPADLDAQLATNLRAPMLLTRRALPALEKSSGTVVNLSTAGSLGRRAW 190 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PG+ Y +K ++D TR A+ LAP+G+RV Sbjct: 191 PGMSVYGATKTALDFLTRTWAVELAPRGIRV 221 >UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase precursor; n=3; Cyanobacteria|Rep: NAD-dependent epimerase/dehydratase precursor - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 251 Score = 83.0 bits (196), Expect = 7e-15 Identities = 44/155 (28%), Positives = 82/155 (52%), Gaps = 3/155 (1%) Frame = +1 Query: 271 SKLGAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 +K A++ + GR + E + V + + +D+TKE+D++ ++ K + +G+LD+ Sbjct: 26 AKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQSDVTKEADVKAMVDKAVGVFGRLDI 85 Query: 448 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 621 NNAG++ E ++ + A+YDR+MN NV+ ++ + +L + G G Sbjct: 86 AFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLSMKYEIAQMLKQGSGAIVNTSSGAG 145 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + + PGV Y SK +V T+ AL A G+R+ Sbjct: 146 VVALPGVPLYTASKHAVVGLTKAAALQYAKAGIRI 180 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 83.0 bits (196), Expect = 7e-15 Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 546 + D+T E+ + +I + ++ G LD L NAG+ +G I A +D L N R+ + Sbjct: 58 VQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRSGAIAGFEQANWDALFAVNARAHF 117 Query: 547 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 + A+PHL S KG G R PG++AY+ SK +V FT +AL LAP +R Sbjct: 118 FGAKHAIPHLQRSGKGSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALALELAPDNIR 177 Query: 724 V 726 V Sbjct: 178 V 178 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 83.0 bits (196), Expect = 7e-15 Identities = 52/184 (28%), Positives = 92/184 (50%), Gaps = 3/184 (1%) Frame = +1 Query: 181 YSEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFAS 357 +S+ N +GKV L++ GAQ+ ++ RN E +V+K+ ++ Sbjct: 2 HSKDQFNLSGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLD 61 Query: 358 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNV 534 T+ I + KE + ++ KTI+ +G++D+LVNNA I G IE S +D++M+ NV Sbjct: 62 TIGIACHIGKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNV 121 Query: 535 RSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 711 ++ + L+ L +PH +K G + G+ Y+ SKA++ T+ A Sbjct: 122 KAPWSLSNLVLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGK 181 Query: 712 KGVR 723 GV+ Sbjct: 182 YGVK 185 >UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 256 Score = 83.0 bits (196), Expect = 7e-15 Identities = 47/151 (31%), Positives = 82/151 (54%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++++ N E + V+ + A +++T D++K +D+ + +++TID +G++D+ +NN Sbjct: 36 GARVAIVDLNGEGAKAVADALQQNA--IAVTCDVSKGADVSRAVQETIDAFGRVDIAINN 93 Query: 460 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSF 633 AG + + R+ NV SI++ T VPH + G GIR Sbjct: 94 AGWSHRNQPALDVDFETFKRVYEVNVDSIFHATHALVPHWRDIGGGVMINVGSTAGIRPR 153 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 PG+ YN SK +V+ T+ +A+ LAP VRV Sbjct: 154 PGLSWYNSSKGAVNMMTKTLAVELAPDRVRV 184 >UniRef50_Q0GJJ3 Cluster: 11-beta-hydroxysteroid dehydrogenase-like protein; n=1; Pinus taeda|Rep: 11-beta-hydroxysteroid dehydrogenase-like protein - Pinus taeda (Loblolly pine) Length = 333 Score = 83.0 bits (196), Expect = 7e-15 Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 3/179 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT--ADL 381 GKVV +K GA L + R L++V+K+C + + ++ ADL Sbjct: 50 GKVVLITGASSGIGQHMAWEYAKRGANLVVVARRRNRLEEVAKECKAYGAQYAVVCPADL 109 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIYYLTM 558 TK D ++I++ T+ +G+LDVLVNNAG E + A+Y R+++ + T Sbjct: 110 TKPQDCKRIVEFTVSTFGRLDVLVNNAGTAGGSLFEEYENAAEYKRIVDIDFWGHVNTTH 169 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 A+ HL +G FP Y+ +K ++ F + + L K V VT++ Sbjct: 170 FALEHLQRRRGQIVVISSMIAFLPFPFTTVYSAAKGALLNFFETLRIELISKSVTVTIA 228 >UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: AGR_C_2317p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 292 Score = 82.6 bits (195), Expect = 9e-15 Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 2/180 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSITAD 378 F+G+VV + GA + +TGRN NL K A + +D Sbjct: 45 FSGQVVVVTGGSTGIGFSVAKLFLEGGASTVYVTGRNSANLDAAVAKLGKGA--IGFVSD 102 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 + K SD+E++ + K+DVLV NAGI E + T A YDR+ + NV+ ++Y Sbjct: 103 VAKLSDLEQLKSRLEADGRKVDVLVANAGIAENNDLGETHEALYDRIFDINVKGVFYTVQ 162 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV-TVS 735 +P +L G G + + AYN SKA+V F R A L +G+RV TVS Sbjct: 163 TLLP-VLRDGGSIVLTGSIVGNKGMERLSAYNASKAAVRSFARSFANDLKGRGIRVNTVS 221 >UniRef50_Q0HN46 Cluster: Short-chain dehydrogenase/reductase SDR; n=16; Alteromonadales|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain MR-4) Length = 267 Score = 82.6 bits (195), Expect = 9e-15 Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 2/177 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLT 384 GKVV ++++G QL L+ RN L ++ + + T + AD++ Sbjct: 6 GKVVIITGASEGIGRALAIAMARVGCQLVLSARNETRLASLALEIANYGPTPFVFAADVS 65 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTML 561 S E +I+ TI HYG+LD+LVNNAG+ E L+ + +M N YLT Sbjct: 66 SASQCEALIQATIVHYGRLDILVNNAGMTMWSRFDELNQLSVLEDIMRVNYLGPAYLTHA 125 Query: 562 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 A+P+L S+G G+ P Y SK +V F + + L V VTV Sbjct: 126 ALPYLKSSQGQVVVVASVAGLTGVPTRSGYAASKHAVIGFFDSLRIELTDDNVAVTV 182 >UniRef50_A7DMA1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methylobacterium extorquens PA1|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 336 Score = 82.6 bits (195), Expect = 9e-15 Identities = 42/155 (27%), Positives = 82/155 (52%), Gaps = 1/155 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA++ L RN E L ++ + ++ + + + D+++ + +E + + ID YG++D VN Sbjct: 35 GARVVLAARNGEALAEIQAEIERHGGAAIHVVTDVSERAQVEALARAAIDRYGRIDTWVN 94 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 636 +AG+ G +E + + RL + N + Y +++A+PHL ES G +FP Sbjct: 95 DAGLSIIGRLEEIEDSDHRRLFDVNFWGVVYGSLVALPHLKESGGTLINLGSVASDVAFP 154 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRVTVSIL 741 Y+ SK ++ FT + + L +G V V+++ Sbjct: 155 LQGMYSASKHAIKGFTDSLRIELKEEGAPVAVTLI 189 >UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE; n=10; Proteobacteria|Rep: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE - Brucella melitensis Length = 262 Score = 82.2 bits (194), Expect = 1e-14 Identities = 51/183 (27%), Positives = 90/183 (49%), Gaps = 6/183 (3%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 ++ GKV +K GA++ + R+ ++V+ + A L++ A Sbjct: 11 VSLEGKVALITGAGSGFGEGMAKRFAKGGAKVVIVDRDKAGAERVAGEIGDAA--LAVAA 68 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 552 D++KE+D++ ++ + +GK+D+LVNNAGI + E ++DR++ NVR +Y + Sbjct: 69 DISKEADVDAAVEAALSKFGKVDILVNNAGIGHKPQNAELVEPEEFDRIVGVNVRGVYLM 128 Query: 553 TMLAVPHLLE--SKG---XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 T +PH E +KG R P + YN +K V T+ +A+ LAP Sbjct: 129 TRKLIPHFKENGAKGQECVILNVASTGAGRPRPNLAWYNATKGWVVSVTKALAIELAPAK 188 Query: 718 VRV 726 +RV Sbjct: 189 IRV 191 >UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR precursor - Clostridium phytofermentans ISDg Length = 258 Score = 82.2 bits (194), Expect = 1e-14 Identities = 50/186 (26%), Positives = 86/186 (46%), Gaps = 6/186 (3%) Frame = +1 Query: 187 EVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA-STL 363 E + GKV +K GA ++L R +E L +V + +K + Sbjct: 2 EKLFDLTGKVAVVTGASSGLGADAALAYAKAGADVALLARRIEKLNEVKAEIEKIGRKVV 61 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 ++ D+T E ++ ++ ID +G +D+L+NNAGI G +++ S+ +D+ +TNV+ I Sbjct: 62 AVGCDVTNEESVKTAMQTVIDTFGHIDILLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGI 121 Query: 544 YYLTMLAVPHLLE---SKGXXXXXXXXXGIRSFPGVL--AYNISKASVDQFTRCVALXLA 708 + + VP + E K F + +YN SKA+V TR +A A Sbjct: 122 FLASKYVVPQMKERGYGKIINIASVNAVVADKFDAFIRHSYNSSKAAVVGLTRGMAASYA 181 Query: 709 PKGVRV 726 G+ V Sbjct: 182 RYGITV 187 >UniRef50_Q9LUF1 Cluster: 11-beta-hydroxysteroid dehydrogenase-like; n=7; core eudicotyledons|Rep: 11-beta-hydroxysteroid dehydrogenase-like - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 82.2 bits (194), Expect = 1e-14 Identities = 57/198 (28%), Positives = 95/198 (47%), Gaps = 3/198 (1%) Frame = +1 Query: 148 QEVFNTVSH*KYSEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK 327 Q +F+T+ +SE N GKVV + GA L+LT R L++ Sbjct: 34 QSIFSTI----FSE---NLYGKVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEE 86 Query: 328 VSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TS 498 V++ + S +++ AD++K D +I+ TI H+G+LD LVNNAG+ + EN Sbjct: 87 VAEIARELGSPNVVTVHADVSKPDDCRRIVDDTITHFGRLDHLVNNAGMTQISMFENIED 146 Query: 499 LAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQ 678 + + +++TN Y T A+P+L +S G + P + YN SKA++ Sbjct: 147 ITRTKAVLDTNFWGSVYTTRAALPYLRQSNGKIVAMSSSAAWLTAPRMSFYNASKAALLS 206 Query: 679 FTRCVALXLAPKGVRVTV 732 F + + L V +T+ Sbjct: 207 FFETMRIELG-GDVHITI 223 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 81.8 bits (193), Expect = 2e-14 Identities = 44/177 (24%), Positives = 85/177 (48%), Gaps = 3/177 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLT 384 GK+ L++ GA++ + R + L+ + K + K L I D+ Sbjct: 6 GKIALVTGASSGIGAATAAKLAEAGAKVGIAARRTDKLEDLKKKIEAKGGEALVIEMDVV 65 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 564 + +E +KK +D YG +D+LVNNAG++ I+ + ++ R+++ NV+ + T Sbjct: 66 DTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAAV 125 Query: 565 VPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK-GVRVT 729 +P ++ + G G + F G+ Y +K +V F+ + + + K G+RVT Sbjct: 126 LPQMIKQHSGHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGLRMEVGQKHGIRVT 182 >UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=19; Bacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 242 Score = 81.8 bits (193), Expect = 2e-14 Identities = 44/156 (28%), Positives = 81/156 (51%), Gaps = 2/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L+K G + L R+ ENL+ V+K+ + + + TAD++ ++ I+ + G +D Sbjct: 30 LAKEGVNVGLLARSEENLKAVAKEVEAEGVKAVIATADVSSYEEVTTAIETLKNGLGSID 89 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 +L+NNAGI + G +A +++++ N+ +YY T A+P ++E + G G Sbjct: 90 ILINNAGISKFGKFLELDVADWEKIIQVNLMGVYYATRAALPSMIEQQSGDIINISSTAG 149 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 + P AY+ SK V T +A+ + +RVT Sbjct: 150 QKGAPVTSAYSASKFGVLGLTESLAMEVRKHNIRVT 185 >UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) reductase precursor; n=1; Rhodopseudomonas palustris|Rep: Putative 3-oxoacyl-(Acyl carrier ptn) reductase precursor - Rhodopseudomonas palustris Length = 262 Score = 81.8 bits (193), Expect = 2e-14 Identities = 49/178 (27%), Positives = 84/178 (47%), Gaps = 1/178 (0%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 372 M F GKV L++ GA + L+ + + L + ++ A +S + Sbjct: 1 MRFNGKVAVVTAAASGIGAATAARLAREGAYVYLSDIDQDALGRQAESLVDVAERISTVV 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 AD+T + +I G+LD+L+NNAG+ G I + + R+ V SI++ Sbjct: 61 ADVTVPEQVSALIDGAARERGRLDILINNAGMGAFGRITEVTPEAWHRVFGICVDSIFHA 120 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + A+PHL++++G G+ G AYN +K +V TR +AL + G+RV Sbjct: 121 SRAAIPHLIKARGTIVNTASISGLFGDYGFAAYNAAKGAVINLTRNMALDYSRDGLRV 178 >UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=5; Cyanobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime) Length = 280 Score = 81.8 bits (193), Expect = 2e-14 Identities = 44/152 (28%), Positives = 77/152 (50%), Gaps = 3/152 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 453 G +L+L R E L++ + + ++ A L++ D+T+ ++ ++++T++ YG++D L+ Sbjct: 26 GYRLALAARTAETLRQTAIELEQSLNAEVLAVPTDVTQPEQVQNLVERTLERYGRIDCLI 85 Query: 454 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRS 630 NNAGI G T+L + LM N Y +P +L+ KG G Sbjct: 86 NNAGICLKGPFLQTTLEHWQALMAVNFWGYLYTIRAVLPDMLKRKKGQIINVGSVGGKMP 145 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P + AY SK +V T + L L P G++V Sbjct: 146 LPQMSAYCASKYAVSGLTEALRLELQPHGIQV 177 >UniRef50_Q1ARR8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 241 Score = 81.8 bits (193), Expect = 2e-14 Identities = 50/175 (28%), Positives = 79/175 (45%), Gaps = 1/175 (0%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD-CDKFASTLSITADLT 384 GKV L++ G +L L GR+ L+ V++ D +++ D+ Sbjct: 6 GKVFAITGASRGIGAATALALAREGCRLGLGGRDEAALEGVARGVADAGGEAVAVRCDVR 65 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 564 + D E++ +T+ +G LD LV NAG+ G + + S Q D +++TN R Y A Sbjct: 66 RYEDCERLASETVGRFGGLDGLVANAGVGAYGGLLDLSPEQIDEMLDTNARGTVYSVRAA 125 Query: 565 VPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 +P LLE G G++ P Y SK + F + L +GVRVT Sbjct: 126 LPALLEGGGDLVIVASVAGLKGLPNESVYCASKHAQVGFAEALDHELRLRGVRVT 180 >UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=2; Bacteria|Rep: Predicted short chain dehydrogenase - Bacillus sp. B14905 Length = 251 Score = 81.8 bits (193), Expect = 2e-14 Identities = 47/156 (30%), Positives = 77/156 (49%), Gaps = 1/156 (0%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 444 ++K GA +++ N E + + KD + + ++ + A+L + + KII ++ YGKLD Sbjct: 26 MAKEGAIVTIVDLNAEAGEAMEKDLQQISPKSMFLQANLMERDQLPKIIDTVVEKYGKLD 85 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 624 VLVNNA + TIE T+ A D T +YL A+PHL E++G GI Sbjct: 86 VLVNNAHAAKQVTIEETTQADLDLSFGTGFYPTFYLMQAALPHLKETQGNIINFASGAGI 145 Query: 625 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 + AY +K ++ +R A G+ V + Sbjct: 146 QGHETQAAYAAAKEAIRGISRVAANEWGRYGINVNI 181 >UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 254 Score = 81.8 bits (193), Expect = 2e-14 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 2/178 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 375 N GKV L GA +++ R L+ D L+ + Sbjct: 7 NLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACST 66 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+T E+ +E+++ T++ +G++D+LVNN+GI+ T + S ++DR++ TN+R + T Sbjct: 67 DITDEASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLAT 126 Query: 556 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 HL+ + G ++ AY+ SKA V FTR +A+ A ++V Sbjct: 127 RAVGRHLVAQRSGKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQV 184 >UniRef50_Q01LD3 Cluster: OSIGBa0132D06.4 protein; n=9; BEP clade|Rep: OSIGBa0132D06.4 protein - Oryza sativa (Rice) Length = 368 Score = 81.8 bits (193), Expect = 2e-14 Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 3/180 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITAD 378 AGKVV ++ GA+L+L R +L +V+ S L++ D Sbjct: 65 AGKVVLVTGASSGIGEQVAYRYARRGARLALVARREASLGEVAARARALGSPDVLAVPGD 124 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT-SLAQYDRLMNTNVRSIYYLT 555 + + D + ++ T++H+G+LD LVNNAG+ E +A + ++++ N + T Sbjct: 125 VARPDDCRRFVQATVEHFGRLDHLVNNAGLANVCWFEEVPDVANFKQVLDVNFWGTVHPT 184 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 A+PHL S+G + + P + YN SKA+V F + + L + V VTV+ Sbjct: 185 HAALPHLKASRGKIFVNSSASAVLAMPRMSFYNASKAAVHNFAETLRMELHGE-VGVTVA 243 >UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep: Blr1409 protein - Bradyrhizobium japonicum Length = 266 Score = 81.4 bits (192), Expect = 2e-14 Identities = 49/179 (27%), Positives = 89/179 (49%), Gaps = 3/179 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 375 + GKV L++LGA++ ++ R + ++V+ + + I Sbjct: 16 DLTGKVAIVTGSSRGIGRSSAELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPC 75 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYL 552 ++ +++++E +I HYGK+D+LV NA + G + + + +D++M +NV+S +L Sbjct: 76 NIARKAEVEALIAGATTHYGKIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWL 135 Query: 553 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + LA+P + E G G+R + AY ISKA+ R +A PKGVRV Sbjct: 136 SALAIPQMAERGNGSVIIISSIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRV 194 >UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 258 Score = 81.4 bits (192), Expect = 2e-14 Identities = 45/154 (29%), Positives = 82/154 (53%), Gaps = 5/154 (3%) Frame = +1 Query: 280 GAQ-LSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 453 GA+ L + GR ++ + C + A+ +++ D+T+E D+ +++ ++ G+LDV Sbjct: 37 GAEALIIAGRREAEIEATAAACREIGAAAIALKTDITREDDVARLVGIAVERCGRLDVAF 96 Query: 454 NNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 627 NNAG E +E YD + +TNVR+++ +P +L + +G G+R Sbjct: 97 NNAGFQERRAPLEEQGTEIYDSVFDTNVRALFLCLRHQLPAMLAQGRGSIVVNASVSGVR 156 Query: 628 S-FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + PG Y+ SKA+ TR A+ AP+G+R+ Sbjct: 157 NPNPGFSLYSASKAAAISLTRSAAMENAPRGIRI 190 >UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aurantiacus J-10-fl Length = 249 Score = 81.4 bits (192), Expect = 2e-14 Identities = 53/181 (29%), Positives = 83/181 (45%), Gaps = 4/181 (2%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSIT 372 M F GKV L GA + L R +E L+ V + D K A TL++ Sbjct: 1 MEFEGKVALVTGAGTGIGEAIAERLLAGGALVVLVSRRLEPLELVCRRIDPKGARTLALE 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIY 546 AD+ +E +K+TI+ +GKLD+ VNNAG+ +++ + +++T++ I+ Sbjct: 61 ADVRNPMAMEAAVKRTIERFGKLDMAVNNAGVTGPAGVPVQDVEAEIWREVIDTDLTGIF 120 Query: 547 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 Y +P +L G G+ G+ AY +K V TR AL LA +R Sbjct: 121 YSMKYEIPAMLANGSGAIVNMSSANGLVGLAGMAAYTAAKHGVIGLTRSAALELAESNIR 180 Query: 724 V 726 V Sbjct: 181 V 181 >UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Jannaschia sp. CCS1|Rep: Short-chain dehydrogenase/reductase SDR - Jannaschia sp. (strain CCS1) Length = 254 Score = 81.4 bits (192), Expect = 2e-14 Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 1/150 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA++++TGR E L+ V+ + +I A D++ E D ++I + H G L L N Sbjct: 30 GAKVTITGRRAEKLEDVA---GAIGPSCAIAAGDVSIEEDRRRMIDTAVAHGGGLQGLFN 86 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 636 NAG + G I + + +MN NV + LT LA PHL E G R+FP Sbjct: 87 NAGNMLRGPITDLAAEDILEVMNVNVVAGMRLTGLAAPHLEEHGGAVVFVGSGHTRRAFP 146 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G Y SK +V+ + +A L PKG+RV Sbjct: 147 GASPYAASKGAVEVLAQVLAAELGPKGIRV 176 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 81.4 bits (192), Expect = 2e-14 Identities = 50/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSIT 372 MNF +VV ++ GA+L+L NV L + + ++ S Sbjct: 2 MNFKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQP 61 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYY 549 D++ E +++ I T H+G+LDV +NNAGI + T+ + ++R+M+ NV+ +Y Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121 Query: 550 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +PH++ + G GI P + AY SK +V T+ VA G+RV Sbjct: 122 CMKYQIPHMIKQGGGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRV 181 >UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribacter dokdonensis MED152|Rep: Putative dehydrogenase - Polaribacter dokdonensis MED152 Length = 277 Score = 81.4 bits (192), Expect = 2e-14 Identities = 47/146 (32%), Positives = 76/146 (52%), Gaps = 1/146 (0%) Frame = +1 Query: 298 TGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 477 T R + + +K+ K A +I D+T E IE IK I + K+DVLVNNAG+ Sbjct: 33 TFRKQSQVDEFNKNSTKNAQ--AILLDITNEKSIEDNIKNIISEHVKIDVLVNNAGVGFV 90 Query: 478 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYN 654 G +E TSL + + N +T +P++ + K G GI++F G YN Sbjct: 91 GAVEETSLKEVRTVFEPNFFGTLKMTQSVLPYMRKEKSGNIVQISSHGGIKAFAGFGIYN 150 Query: 655 ISKASVDQFTRCVALXLAPKGVRVTV 732 SK +++ F+ +A +AP G++V++ Sbjct: 151 ASKFALEGFSEAMAQEVAPLGIKVSI 176 >UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Synechococcus|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime) Length = 291 Score = 81.0 bits (191), Expect = 3e-14 Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 2/181 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 ++ A +VV +K GA+L L R E LQ V +K + L + Sbjct: 2 LSLANQVVLITGASAGIGKAVALEAAKRGARLVLAARREELLQNVKDLVEKQGTEALVVP 61 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+ + +E + +K +D +G++D+LVNNAG + G +E +A R NV ++ L Sbjct: 62 TDMADTAQVEALAQKALDRFGRVDILVNNAGYGQMGPVEEVDVAAMRRQFEVNVFGLHAL 121 Query: 553 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 T +P + E G G S P Y+ +K +V+ + + + +AP G++V Sbjct: 122 TRALLPQMRERGSGRILNLSSVAGQMSMPFSGVYSATKFAVEALSDALRVEVAPFGIKVI 181 Query: 730 V 732 V Sbjct: 182 V 182 >UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=1; Halothermothrix orenii H 168|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Halothermothrix orenii H 168 Length = 243 Score = 81.0 bits (191), Expect = 3e-14 Identities = 44/123 (35%), Positives = 68/123 (55%), Gaps = 1/123 (0%) Frame = +1 Query: 346 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 525 K +TL + ADLT + K++++ I +G+LD++VN+AGI G IE TS A++++ Sbjct: 44 KGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVNSAGITGVGNIETTSPAEFEKQFA 103 Query: 526 TNVRSIYYLTMLAVPHLLESKGXX-XXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALX 702 NV + AV L + G G++ P +AY SKA+V FT+C+AL Sbjct: 104 VNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCMALD 163 Query: 703 LAP 711 L P Sbjct: 164 LGP 166 >UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family precursor; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Oxidoreductase, short chain dehydrogenase/reductase family precursor - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 252 Score = 81.0 bits (191), Expect = 3e-14 Identities = 56/179 (31%), Positives = 84/179 (46%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSIT 372 M GKV L+ GA++ + GR E L + V ++ L+I Sbjct: 1 MKLKGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIP 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 +D+TK DIEK + + YG+LD+LVNNAG TSL +DR+ ++RS++ + Sbjct: 61 SDVTKIEDIEKARDEVRETYGRLDILVNNAGSALFKPFMKTSLEDFDRIYQVDLRSVFAV 120 Query: 553 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + L +P +LE G G+ AY K V Q TR +A L P+ +RV Sbjct: 121 SQLMLPLMLEGGGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAELGPE-IRV 178 >UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6; Pseudomonas aeruginosa|Rep: Probable short-chain dehydrogenase - Pseudomonas aeruginosa Length = 252 Score = 80.6 bits (190), Expect = 4e-14 Identities = 38/118 (32%), Positives = 67/118 (56%) Frame = +1 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 ADL + ++ K + G+LD LVN AG+ G +EN + +D ++ N+++ +Y+ Sbjct: 55 ADLRSADNCHTLMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYM 114 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+P+L E++G G +++ G AY SKA++ ++ +AL LA +GVRV Sbjct: 115 CQAAIPYLKENQGSIVNISSDSGRQAYRGSAAYCASKAALTMLSKTLALELAEQGVRV 172 >UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=2; Bacillaceae|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. B14905 Length = 248 Score = 80.6 bits (190), Expect = 4e-14 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = +1 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYL 552 ++ +E + I ++ +D YG++D LVN GI + T IE ++ +++RLM+ NV+S++ Sbjct: 56 NVLQEERVNDIFQQIVDKYGRIDGLVNALGIAQAATPIEQVTMDEWNRLMDVNVKSLFIT 115 Query: 553 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 VP + + KG +R PG+ AY SK + + FTR +A+ LAP +RV Sbjct: 116 AKAVVPFMKKQQKGSIVTIASISAVRPRPGLQAYIASKGAAESFTRGLAIELAPNQIRV 174 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 80.6 bits (190), Expect = 4e-14 Identities = 50/176 (28%), Positives = 85/176 (48%), Gaps = 2/176 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 381 AGKV + GAQ+ + + E Q + ++ A L + AD+ Sbjct: 14 AGKVALITGAGSGIGRATALLFATEGAQIVVCDLDPEGGQATVRAIEQAGAQALFVQADV 73 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 + +D + +++T+ H+ +LDVL NNAGI + +TS A +D +M NV+SI+ ++ Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133 Query: 562 AVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 AVP + E G G+ ++Y +K +V TR +AL P+ +RV Sbjct: 134 AVPVMAEQGGGSIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDHGPQRIRV 189 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 80.6 bits (190), Expect = 4e-14 Identities = 44/152 (28%), Positives = 79/152 (51%), Gaps = 4/152 (2%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ L RN+E L+ K+ ST ++T DL ES +++ + +D YGK+D+LVNN Sbjct: 29 GAKVILIARNLEGLENTRKEIGNEDSTAAMTCDLVDESQTLQVVNQIMDTYGKIDILVNN 88 Query: 460 AGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 633 AG I ++ +L+N N+ ++ +T + + + K G R+ Sbjct: 89 AGAINDPIHFHEMQNSEIQKLINVNLLGVFNMTKAVLTKMADVKSGSIVNIGSISSERAI 148 Query: 634 PGV--LAYNISKASVDQFTRCVALXLAPKGVR 723 P V Y+ +KA++ FT+ +A+ A + +R Sbjct: 149 PRVHLAVYSATKAAIPMFTKSIAVEYARRNIR 180 >UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 254 Score = 80.2 bits (189), Expect = 5e-14 Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 8/163 (4%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLD 444 L++ GA ++L R + L++++ D T L + D+T ++ +K+T+ G+LD Sbjct: 27 LARHGAAMALVARRGDRLERLAADITGAGGTALPLPLDITDQAQAADAVKRTVAELGRLD 86 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 621 +VNNAGI+ G I + ++DR++ N++ + Y+T A+PHLL + G Sbjct: 87 TVVNNAGIMLPGPILDAPTEEWDRMVALNLQGLLYVTHAALPHLLTAADGGPRQVADLVN 146 Query: 622 IRSFPGVLA------YNISKASVDQFTRCVALXLAPKGVRVTV 732 I S G A YN++K V+ FT + + + VRV+V Sbjct: 147 ISSVAGRHATMGAGIYNLTKFGVNAFTESLRQEVTARHVRVSV 189 >UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 249 Score = 80.2 bits (189), Expect = 5e-14 Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA L L R+ E L VS+ + A + + D+T + ++ + + +G LD+LVN Sbjct: 30 GAHLLLADRDEERLAAAVSRYSEGEAKAVGVVVDVTDPDQTKMMVDRCLAEFGALDILVN 89 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 633 AG++ + +A +D +++ ++RS++ AVPH+L + G GI+ Sbjct: 90 CAGLLTEVPLAEMDVATWDEMISVDLRSVFLCCRWAVPHMLAQGSGRIINISSQLGIKGG 149 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G++ Y +KA V TR +A LAP GV V Sbjct: 150 VGLVHYCAAKAGVIGLTRALARELAPSGVLV 180 >UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 252 Score = 79.8 bits (188), Expect = 6e-14 Identities = 45/147 (30%), Positives = 73/147 (49%), Gaps = 1/147 (0%) Frame = +1 Query: 289 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 468 + L G +E+L SK L++ D+++ +D++ + I +GK+D+L NNAGI Sbjct: 35 IDLDGGKLEHL--ASKITSSGGICLALRGDVSQSADVQNALNTAIGRFGKIDILFNNAGI 92 Query: 469 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVL 645 + G I+ T+ Q+DR M NV+S+Y VPH E G +R+ Sbjct: 93 VPAGKIDVTTEEQWDRAMAINVKSMYLFCHAIVPHFKEHGGGVILNTASATALRAVVDRA 152 Query: 646 AYNISKASVDQFTRCVALXLAPKGVRV 726 Y +KA+V T+ +AL +RV Sbjct: 153 CYTATKAAVVGLTKSMALDYVRDNIRV 179 >UniRef50_Q128G0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 270 Score = 79.8 bits (188), Expect = 6e-14 Identities = 48/156 (30%), Positives = 75/156 (48%), Gaps = 4/156 (2%) Frame = +1 Query: 274 KLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 450 + G L L RN L +V+ C A TL + D++ E+ ++I + +G++D L Sbjct: 26 RTGVALVLAARNEALLAEVAAQCAAHGAQTLVVKTDVSVEAQCRQLIAAAVARFGRIDAL 85 Query: 451 VNNAGIIETGTIENTS---LAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 621 VNNAG E+ LA Y++LM N+ + T A+PHL +S+G G Sbjct: 86 VNNAGRSAQALFEDVKAEDLAWYEQLMRINLWGSVWCTHAALPHLKQSRGAIVAVSSLAG 145 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 + PG AY+ +K ++ F + L GV VT Sbjct: 146 LIGVPGRTAYSATKFAMTGFFEALRAELKGAGVSVT 181 >UniRef50_A6GPQ6 Cluster: Short chain dehydrogenase; n=1; Limnobacter sp. MED105|Rep: Short chain dehydrogenase - Limnobacter sp. MED105 Length = 272 Score = 79.8 bits (188), Expect = 6e-14 Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 456 G +L L R +E LQ+V K + + A D+ +++ E ++++++ +G +D++VN Sbjct: 29 GNKLVLAARRLEKLQEVGKQVEAAGGQVHCVACDVMEQAQCENLVEESVKAFGGIDMIVN 88 Query: 457 NAGIIETGTIEN-TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 633 NAG+ E+ T L ++RL NV S+ ++T A+PH+ +SKG G Sbjct: 89 NAGVSMHAWFEDITDLGTFERLFRVNVMSMVWITHKALPHIKKSKGLIVGVSSLAGKTGV 148 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P Y SK ++ F + + L GV V Sbjct: 149 PARTTYCTSKFAMSGFMEALRIELMGTGVDV 179 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 79.8 bits (188), Expect = 6e-14 Identities = 47/152 (30%), Positives = 80/152 (52%), Gaps = 3/152 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQK--VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 453 GA++ +T + E K V++ K S ++I AD+ E D++K+I K YG+LD+LV Sbjct: 31 GAKVVITWESHEESAKNVVNEIHHKNGSAMAIQADVRNEDDVKKVINKIKGEYGRLDILV 90 Query: 454 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 630 NNAGI++ + T ++D L+ TN + + + A +L+ K G G+ Sbjct: 91 NNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYSRAAAKLMLKHKSGRIINISSVVGVYG 150 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G Y+ +K+ + FT+ +A L P G+ V Sbjct: 151 SKGQSVYSATKSFLIAFTKSLAKELGPFGITV 182 >UniRef50_Q8YSW6 Cluster: Oxidoreductase; n=3; Nostocaceae|Rep: Oxidoreductase - Anabaena sp. (strain PCC 7120) Length = 293 Score = 79.4 bits (187), Expect = 9e-14 Identities = 38/147 (25%), Positives = 78/147 (53%), Gaps = 2/147 (1%) Frame = +1 Query: 295 LTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII 471 L R ++ L+ ++ + + ++I+ D+ + + +++K I H+G++DVL+NNAGI Sbjct: 52 LAARQLDRLEAIATEIREMGQQAIAISTDVKDATQVNNMMQKAIAHFGQVDVLINNAGIF 111 Query: 472 ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLA 648 G++EN SL + ++++TN+ + +PH L+ G G+ P + Sbjct: 112 CLGSVENFSLEDWHQIIDTNLWGYIHTIHAILPHFLQRGAGTIVNVSSIGGLEPIPYHVP 171 Query: 649 YNISKASVDQFTRCVALXLAPKGVRVT 729 Y SK ++ T+ + L+PK + V+ Sbjct: 172 YTASKYAITGLTKSLHAELSPKNIHVS 198 >UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 268 Score = 79.4 bits (187), Expect = 9e-14 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 3/152 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GAQ+ RN ++ +K D+ + TAD+++ ++IE ++ + YG++DVL N Sbjct: 35 GAQVFCVDRNGTAAEETAKIINDEGGKATAFTADVSRSAEIEAMVAACLKAYGRIDVLDN 94 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 636 N GI E G++ + +DR+ + N++S Y+ +P ++E G Sbjct: 95 NVGIAEMGSVVEVTEESWDRVFSVNLKSAYFAMKHVIPVMVEQGGGSIINISSIASIRHM 154 Query: 637 GV--LAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ + Y SKA+++Q TR A+ A VRV Sbjct: 155 GISYVTYGTSKAAMNQMTRTTAIEFARHHVRV 186 >UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Salinibacter ruber DSM 13855|Rep: NAD-binding domain 4, putative - Salinibacter ruber (strain DSM 13855) Length = 241 Score = 79.4 bits (187), Expect = 9e-14 Identities = 49/156 (31%), Positives = 76/156 (48%), Gaps = 6/156 (3%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA + R+ + LQ + D ++ + ++ D+ E IE + D G+LDVLVNN Sbjct: 29 GATVCGLARSTDALQALHDDLG--SAFVPVSCDVRNEDAIESAFETVDDEAGRLDVLVNN 86 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK------GXXXXXXXXXG 621 AG+ + G +++ +D M+TNVR +Y T AVP + E G G Sbjct: 87 AGLGQFGPVDDLDTDAFDVQMDTNVRGVYLCTREAVPRMREQNEATGFGGHIVNIASIAG 146 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 + P + AYN SK +V F+ V + G+RVT Sbjct: 147 LLGNPNISAYNASKFAVRGFSEAVMKEVREDGIRVT 182 >UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Micromonospora sp. ML1|Rep: NAD or NADP oxidoreductase - Micromonospora sp. ML1 Length = 264 Score = 79.4 bits (187), Expect = 9e-14 Identities = 48/148 (32%), Positives = 75/148 (50%) Frame = +1 Query: 283 AQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNA 462 A + GR L++++ D +T + AD+T+ E ++ +G + LVNNA Sbjct: 46 ANVVAVGRREAALRELTGDGGGQVAT--VAADITEPGAAEHVVAAATTRFGTVHGLVNNA 103 Query: 463 GIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGV 642 G+ T++ S +DRL+ TNVR+ L A+PHL E +G + + PG Sbjct: 104 GLARFATLDTASDEDFDRLLATNVRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGR 163 Query: 643 LAYNISKASVDQFTRCVALXLAPKGVRV 726 Y SKA+++ TR +A LAP VRV Sbjct: 164 SFYGASKAALNSLTRSLARELAP-DVRV 190 >UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 259 Score = 79.4 bits (187), Expect = 9e-14 Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 1/121 (0%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 546 + DL++ + E+++++ + G LDVLVNNAGI +T YD + + N++ + Sbjct: 59 VRGDLSRVPECERVVEEAAEALGGLDVLVNNAGITRALDFLDTDEETYDAIFDLNMKGYF 118 Query: 547 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 + AVPH+LE+ G G FP AY +K ++ FTR +A+ LA +G+R Sbjct: 119 FCARSAVPHMLEAGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIR 178 Query: 724 V 726 V Sbjct: 179 V 179 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 79.4 bits (187), Expect = 9e-14 Identities = 43/175 (24%), Positives = 82/175 (46%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 381 F KV L++ GA + L N + ++ D A +++ D+ Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGAHVVLADVNDNGGKSIAADLGPTA--MAVKCDV 63 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 + +++E ++K ++ +G++D+L NNAGI GT A+++R++ ++ S+YY Sbjct: 64 SSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYACHF 123 Query: 562 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+PH+ G+ AYN +K +V +TR +A+ G+RV Sbjct: 124 AIPHMPRG-SAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALAVDHGRDGIRV 177 >UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Roseiflexus castenholzii DSM 13941|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus castenholzii DSM 13941 Length = 260 Score = 79.4 bits (187), Expect = 9e-14 Identities = 45/153 (29%), Positives = 77/153 (50%), Gaps = 1/153 (0%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 450 ++ G + + N++ L K + + D + L+I D+ + I++T+ HYGK+D + Sbjct: 28 ARAGGSVVIADINLD-LAKATLERDLQGNGLAIQCDVASSESVRAAIEQTLAHYGKIDAI 86 Query: 451 VNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 627 NNA I + + TS Q+D LM TN++S+YY T + L S+G G+ Sbjct: 87 HNNAAISRPSAPLHETSEEQWDALMATNLKSVYYTTFYGIDALKASRGCILNTASMVGVL 146 Query: 628 SFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 AY +K ++ T+ +AL A G+RV Sbjct: 147 GQERHAAYVATKGAMIALTKAMALDYASYGIRV 179 >UniRef50_Q01LD2 Cluster: OSIGBa0132D06.5 protein; n=2; Oryza sativa|Rep: OSIGBa0132D06.5 protein - Oryza sativa (Rice) Length = 355 Score = 79.4 bits (187), Expect = 9e-14 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 3/178 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITAD 378 AGKVV ++ GA L+L R E+L++V S L + D Sbjct: 50 AGKVVLITGASSGIGEHLAYEYARRGAYLALVARREESLREVGDAALAAGSPGVLVVAGD 109 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIYYLT 555 ++ D K + TI ++G+LD LVNNA I + G E T + + +LM+ N Y T Sbjct: 110 VSSPDDCRKFVDDTIRYFGRLDHLVNNASIWQVGKFEELTDVNHFRKLMDINFWGHVYPT 169 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 A+PHL +++G P YN SKA+ + + LA G+ +T Sbjct: 170 RHAIPHLKKTRGRIVGVTSNSSYIFMPRNTFYNASKAAAANLYETLRMELAGDGIAIT 227 >UniRef50_A7RI27 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 309 Score = 79.4 bits (187), Expect = 9e-14 Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 7/183 (3%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS----- 366 F GKVV +K G++L L+ R + L++V +C + L+ Sbjct: 49 FNGKVVWITGASSGIGEHLAYEFTKHGSKLVLSARREKRLEQVKNNCLERGLPLAAEDIL 108 Query: 367 -ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 + DLTK ++ +K + H+G++DVLVNNAG I NT L ++++TN+ Sbjct: 109 VLPLDLTKFDTHSELAEKAVQHFGRVDVLVNNAGTASLDYIRNTPLRLTKKVLDTNILGT 168 Query: 544 YYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 +T +PH+L+ KG G +FP + Y SK ++ + + + L + + Sbjct: 169 ISVTEAVLPHMLKRGKGHIAVVNSIMGKFAFPLIAPYVTSKFGLEGYFKVLRFELLSRNI 228 Query: 721 RVT 729 VT Sbjct: 229 DVT 231 >UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=3; Pezizomycotina|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Aspergillus clavatus Length = 249 Score = 79.4 bits (187), Expect = 9e-14 Identities = 42/124 (33%), Positives = 66/124 (53%), Gaps = 2/124 (1%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVR 537 +++ AD++K DI +++K T+D +GK+DVLV NAG++ + G + + + +D L NVR Sbjct: 57 IAVQADVSKREDIARLVKTTVDRFGKIDVLVLNAGLLWQKGDLLSITEQDFDTLFAANVR 116 Query: 538 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALXLAPK 714 S + A PHL E P L Y SK +V+Q TR +A L + Sbjct: 117 SPLFTIQEAAPHLTEGGRVMLFSTSLAAFSGVTPNYLLYAASKGAVEQMTRVLAKDLGRR 176 Query: 715 GVRV 726 G+ V Sbjct: 177 GITV 180 >UniRef50_Q3IPT1 Cluster: Predicted dehydrogenase; n=2; Halobacteriaceae|Rep: Predicted dehydrogenase - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 257 Score = 79.4 bits (187), Expect = 9e-14 Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 3/154 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 G + L RN +L V+ DC+ S L++ D+T+ + ++ TID +G+LD +V Sbjct: 40 GTNVVLAARNETSLTAVADDCEAAGSNALAVPTDVTEYDAVAALVDATIDRFGRLDTVVV 99 Query: 457 NAGIIETGTIENTSLA--QYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 630 NAGI E + + L Q++R+ TNV YY T A+P L ++ G G Sbjct: 100 NAGIGEKRDVPMSELPLEQFERVTETNVHGAYYTTKAALPALSDANGSLVFVGSYKGKHP 159 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 Y SK + F VA + P GV VT+ Sbjct: 160 STSTPVYAASKWWLRGFALSVAGRVGPDGVGVTL 193 >UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=1; Pseudoalteromonas haloplanktis TAC125|Rep: 7-alpha-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 264 Score = 79.0 bits (186), Expect = 1e-13 Identities = 47/159 (29%), Positives = 87/159 (54%), Gaps = 6/159 (3%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 444 L+ GA + +T R +E++++ + + S L + D+ E + ++ KTI+H+G+LD Sbjct: 31 LADAGADIVVTARTIEDIEQTAAQIRQRGSRALVVACDVLDEQQRQSLVDKTIEHFGRLD 90 Query: 445 VLVNNAGIIETGTIENT---SLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXX 609 +LVNN G +G I+ T S A+ + N + + L+ ++ PH++ + +G Sbjct: 91 ILVNNVG--GSGAIKPTLSSSAAELENCFKLNTATAFDLSRISAPHMVNTSGQGSIINIS 148 Query: 610 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G + PG ++Y I+KA+++ T +A APK VRV Sbjct: 149 SVAGQLAQPGFISYGIAKAALNFMTLNLAQDFAPK-VRV 186 >UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacter caesariensis|Rep: Pteridine reductase - Neptuniibacter caesariensis Length = 246 Score = 79.0 bits (186), Expect = 1e-13 Identities = 43/124 (34%), Positives = 68/124 (54%) Frame = +1 Query: 355 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 534 S + +ADL + ++ + + H+G+L++L+NNA IE TSL Q+D L+N+N+ Sbjct: 57 SAKTFSADLNNLEQLNQLAEDILRHFGQLNLLINNASTFYPTPIEETSLHQWDELINSNL 116 Query: 535 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 R+ Y+L L ES G R PG Y+I+KA ++ T+ +A LAP+ Sbjct: 117 RAPYFLCATLSKTLRESNGCIINMIDIHAQRGLPGYPIYSIAKAGLEMLTKSLAKELAPQ 176 Query: 715 GVRV 726 VRV Sbjct: 177 -VRV 179 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 79.0 bits (186), Expect = 1e-13 Identities = 41/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%) Frame = +1 Query: 406 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LE 582 +I T+ +G+LD+LVNNAGI G + SL +D L+ NV S++Y A+PH+ + Sbjct: 72 LIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRAAIPHMRRQ 131 Query: 583 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G G+R AY+ SKA+V FTR +AL A + +RV Sbjct: 132 GGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADENIRV 179 >UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 269 Score = 79.0 bits (186), Expect = 1e-13 Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 6/178 (3%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 387 GKV L+ GA + + E + ++ D A +++ DL + Sbjct: 10 GKVAIVTGGAGGIGEATARLLTARGACVVIADIAFERAEALAAD---LAGAIALPLDLEQ 66 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAGII------ETGTIENTSLAQYDRLMNTNVRSIYY 549 E +E ++++T+ H+G+LDVL NNA ++ G +E A +DR NVR Sbjct: 67 EQSVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWDRTFAVNVRGTMI 126 Query: 550 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 A+PHL E++G ++ AY+ SKA+V Q TR +A GVR Sbjct: 127 ACRAALPHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAIAASHGKAGVR 184 >UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudomonas fluorescens (strain PfO-1) Length = 260 Score = 78.6 bits (185), Expect = 1e-13 Identities = 51/179 (28%), Positives = 82/179 (45%), Gaps = 3/179 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITA 375 + AG+ V GA++ LT R VE L +V+KD + LS+ Sbjct: 10 SLAGRTVLITGASSGIGAHLARVAGHAGARVVLTARRVERLAQVAKDIEWDCGQALSVEL 69 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+T + +E H+G +DV++NNAGI S Q+ +++TN+ ++ + Sbjct: 70 DVTDRNSVEAAFDAAEAHFGVVDVVLNNAGIGNGQRPLEISEEQWREMLSTNLDGVWRVA 129 Query: 556 MLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +A L ++ KG G+R G Y +KA V Q T+ +AL LA +RV Sbjct: 130 QVAAQRLAKAGRKGSIVNVASILGLRVSTGYSHYCAAKAGVVQLTKSLALELARYNIRV 188 >UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 255 Score = 78.6 bits (185), Expect = 1e-13 Identities = 49/157 (31%), Positives = 85/157 (54%), Gaps = 4/157 (2%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 444 L++ GA ++++GR+ E KV ++ L ITAD+T++ D++++ + I G LD Sbjct: 31 LAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADITRQDDVDRMTAEAISALGHLD 90 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 621 +LVNNAG + + Q+D + + NV++++ ++ A H+ E G G Sbjct: 91 ILVNNAGTCYHAESWDVTEEQWDSVFDLNVKALWACSLAAGAHMRERGSGSIVNIGSMSG 150 Query: 622 -IRSFPGVL-AYNISKASVDQFTRCVALXLAPKGVRV 726 I + P + AYN SKA+V T+ +A P G+RV Sbjct: 151 LIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRV 187 >UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=15; Fungi/Metazoa group|Rep: Nonribosomal peptide synthetase 10 - Gibberella moniliformis (Fusarium verticillioides) Length = 1284 Score = 78.6 bits (185), Expect = 1e-13 Identities = 46/177 (25%), Positives = 83/177 (46%), Gaps = 2/177 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADL 381 AGKV L+K GA +++ R E L+ V K + + I D+ Sbjct: 1042 AGKVAVVTGASSGIGAAVAAGLAKEGAHVAIAARRTEALEGVKKKISVYGGKVLIHKTDV 1101 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 TK+ ++E ++K+ + G +D+LV+ AG++ + N +++R ++ N + + + Sbjct: 1102 TKKVEVESLMKEATEQLGLVDILVSCAGVMYFTMMANNQTDEWERTVDVNCKGLLHCLSS 1161 Query: 562 AVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 VP +L G G + FPG+ Y+ SK V+ + + L A G+RVT Sbjct: 1162 TVPGMLSRGAGHIVAISSDAGRKVFPGLGVYSASKFFVEATLQALRLETAGSGLRVT 1218 >UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 248 Score = 78.2 bits (184), Expect = 2e-13 Identities = 44/156 (28%), Positives = 79/156 (50%), Gaps = 1/156 (0%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 L+ LGA + + R E+ Q+V++ + A + D+TKE + + + + I+ +G+LDV Sbjct: 26 LASLGAIVGVAARKDEDAQEVAEMIGE-AHAFPVQLDVTKELEWKTAVDEIINKFGRLDV 84 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGI 624 LVNNAG ++ + T+L Y +L+N N ++ +P + + KG Sbjct: 85 LVNNAGALKRKPFKETTLDDYQQLINVNQLGVFMGMQAVIPQMEKQQKGSIINNVSISAF 144 Query: 625 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 AY +K+SV ++ A+ L P G+RV + Sbjct: 145 APISQSSAYAATKSSVVAMSKAAAIELGPAGIRVNM 180 >UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 254 Score = 78.2 bits (184), Expect = 2e-13 Identities = 44/178 (24%), Positives = 83/178 (46%), Gaps = 2/178 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITA 375 N GKV L++ GA + + R +L V+++ +L++ Sbjct: 7 NLEGKVAIVTGGSRGFGKAIALGLAQAGADVVVASRTQADLDAVAEEIRALGRKSLAVAT 66 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+ IE + KT++ +GK+D+LVNNAG T + Q+D++++ N++ + T Sbjct: 67 DMLDRGSIENLAAKTMEAFGKIDILVNNAGQGWTVPFLKWTDEQWDQILDVNLKGYFLCT 126 Query: 556 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + H+ ++K G G P ++ Y SK ++ T+C+A A +G+ V Sbjct: 127 QIVGQHMFKAKAGRVINISSAMGSYPLPYMVPYAASKGGINAMTKCLAQEWATRGITV 184 >UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n=7; Firmicutes|Rep: Sorbitol-6-phosphate 2-dehydrogenase - Clostridium botulinum A str. ATCC 3502 Length = 261 Score = 78.2 bits (184), Expect = 2e-13 Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 3/180 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKF-ASTLSI 369 MNF K V ++ GA + + N E KVS++ +K+ ++++ Sbjct: 1 MNFKEKTVIITGGAQSLGEYIAYSFAEKGANIVIADINYEQANKVSQNIINKYKVRSIAV 60 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+ KE +++ +IK TID++ K+D+L+ NAG++ + + ++D ++N N+ + Sbjct: 61 KVDVCKEEEVKNLIKNTIDNFSKIDILICNAGVVYSTKVTELPKEKWDNILNVNLTGYFL 120 Query: 550 LTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A +++ K G G + AY+ SK T+ +AL LA G+RV Sbjct: 121 CAKEAAKEMVKRKQGVIIDINSKSGKKGSLHNCAYSASKFGAIGLTQSLALDLAEDGIRV 180 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 78.2 bits (184), Expect = 2e-13 Identities = 49/183 (26%), Positives = 84/183 (45%), Gaps = 3/183 (1%) Frame = +1 Query: 187 EVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS 366 E TM K V + GA + + N E L + +D +F +S Sbjct: 17 EATMKLKNKTVIVTGAAQGLGYACALRFLQDGANVVMADVNAEKLAESVQDLIEFDGAVS 76 Query: 367 -ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 + D+TK +++ ++ + +YG LDV++NNAGI + S +YD +M+ N+R Sbjct: 77 SMVCDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGA 136 Query: 544 YYLTMLAVPHLL-ESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 + T +A ++ + K G + + P + Y ISK ++Q T A+ LAP Sbjct: 137 FIGTQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPHN 196 Query: 718 VRV 726 +RV Sbjct: 197 IRV 199 >UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 252 Score = 77.8 bits (183), Expect = 3e-13 Identities = 42/149 (28%), Positives = 78/149 (52%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++++ R+ LQ+ + + + L+I AD+T +++ EK+ + ++ YG +D+LVNN Sbjct: 31 GAKVAIVARDAHGLQEAKR---QLGNVLTIQADVTDKNEREKVFSQLLETYGTIDILVNN 87 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AG G I T L+ ++ + N S + + LA+P + + R G Sbjct: 88 AGGSNGGLISETELSLFEEAFSLNYFSAVHFSQLALPVMKAKQSGAIINISSIFGRESGG 147 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRV 726 YN +KA++ FT+ +A + G+RV Sbjct: 148 KATYNSAKAAMISFTKSLADEVIRDGIRV 176 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 77.8 bits (183), Expect = 3e-13 Identities = 41/118 (34%), Positives = 64/118 (54%), Gaps = 2/118 (1%) Frame = +1 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+T E+D+ ++ + + H+G+LDVLVNNAGI +LAQ+ R+++ NV ++ Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 553 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 T A+PH+ G GI P V AY+ SKA+V + A+ A K +R Sbjct: 129 TRAAIPHIDAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAVRMMAKVDAMLYAAKNIR 186 >UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 244 Score = 77.8 bits (183), Expect = 3e-13 Identities = 43/125 (34%), Positives = 67/125 (53%), Gaps = 4/125 (3%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI---IETGTIENTSLAQYDRLMNTN 531 LS+ AD+T + +E ++ +D +G++D+LVNNAGI E +T + Q+D + N Sbjct: 49 LSLEADVTDPAGVESAVEAILDAFGRVDLLVNNAGITGSAEATVCHDTPVEQWDLVHAVN 108 Query: 532 VRSIYYLTMLAVP-HLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 708 VR + T +P L++ G G+ +FPG AY SK + FTR +A+ A Sbjct: 109 VRGPFLCTRAVLPTMLIQKSGHVITVASVAGLVAFPGRCAYTASKGAAIAFTRSLAVDYA 168 Query: 709 PKGVR 723 GVR Sbjct: 169 AAGVR 173 >UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 268 Score = 77.8 bits (183), Expect = 3e-13 Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 L+ +GA +++ NVE ++ + + D ++ D+T E +E +++ D G +DV Sbjct: 42 LTDMGADVAIADVNVEKAERTASELDGETDVIATEVDVTDEGSVEAMVEDVTDRLGPIDV 101 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGI 624 LVNNAGI+E E TS+ + R+++ N+ ++ +L +G G Sbjct: 102 LVNNAGIVENSPAEETSVESWRRVVSVNLDGVFLCAKHVGQQMLNRGEGRIVNISSMSGF 161 Query: 625 R-SFPGVLA-YNISKASVDQFTRCVALXLAPKGVRV 726 + P A YN +KA V T+ +A+ +GVRV Sbjct: 162 DVNVPQKQASYNTTKAGVRMLTQSLAVEWGDQGVRV 197 >UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 246 Score = 77.4 bits (182), Expect = 3e-13 Identities = 47/176 (26%), Positives = 83/176 (47%), Gaps = 2/176 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLT 384 GKV L+K GA +SL R E LQ V K+ D + + D+T Sbjct: 4 GKVAIVTGASSGIGIGIALELAKAGASVSLAARREEKLQDVKKEIEDVGGKAMFVKTDVT 63 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 564 ++ +IKKT + +G +D+LVNNAGI ++N ++++++ N + + Sbjct: 64 VRQQVKDLIKKTEEEFGPVDILVNNAGIGYITYMKNLHEDAWEKMIDVNCKGVLNGIGAV 123 Query: 565 VPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 +P ++E K G G +FP Y +K V+ +R + + + +G++VT Sbjct: 124 LPGMMERKRGHIVNISSNAGRAAFPLFAVYTGTKFFVEGVSRSLRMEVKDEGIKVT 179 >UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 273 Score = 77.4 bits (182), Expect = 3e-13 Identities = 44/151 (29%), Positives = 76/151 (50%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 G + ++GR E L+++ ++ L+ +D+ + +++ + YG+LD LV N Sbjct: 28 GHHVVISGRRAEPLRRLERE----TGALACPSDVGDPDAADGLVRTALAAYGRLDGLVLN 83 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AGI G + + SL + +M TNV L A+PHLL++KG +R+ Sbjct: 84 AGIGRGGAVGDVSLEDWHDVMRTNVTGPLLLLRAAIPHLLDTKGAVVAVASVSALRNGAS 143 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 + Y SKA++ Q R VA+ +GVR + Sbjct: 144 NVPYATSKAALLQLCRSVAVDYGRQGVRANI 174 >UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; Yersinia|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Yersinia pestis Length = 248 Score = 77.4 bits (182), Expect = 3e-13 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 3/155 (1%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 S++G + +GR E + + D + L + AD+ ESDI+ +I+ T++ +G LDV Sbjct: 23 SEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDV 82 Query: 448 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 621 VN AG + ET I+ + + + NTNV +P ++E KG G Sbjct: 83 AVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAG 142 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + P Y SK +++ T+ AL +A GVR+ Sbjct: 143 LVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRI 177 >UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 296 Score = 77.4 bits (182), Expect = 3e-13 Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 3/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSI 369 ++ G+V L+ GA +++ R V+ L++ + D L++ Sbjct: 41 LDLTGRVAIVTGGGTGIGAATARLLAAHGADVAVAARTVDELERTAADIRAATGRRCLAV 100 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+ E + +++++T++ G++DVLVNNAG G + + +D + NVR+ Y+ Sbjct: 101 PTDVKDEEQVIRLVRRTVEELGRIDVLVNNAGGTRMGPLSSLPTRAWDASFDLNVRAAYF 160 Query: 550 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 T A HL+ + G G+ G Y +KA++ FT A GVR Sbjct: 161 CTREAGRHLVAQRSGAIVNISSDAGLHGVRGGAHYASAKAALQMFTTVTAAEWGRYGVR 219 >UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia metallidurans CH34|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 269 Score = 77.4 bits (182), Expect = 3e-13 Identities = 43/155 (27%), Positives = 86/155 (55%), Gaps = 4/155 (2%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 ++LGA++ + R+ + + + + + + D+ +E++I ++ + +H+G +DV Sbjct: 36 ARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDV 95 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 624 L +N GI +TG + +T + +D N NVRS+ + +P ++E +G G+ Sbjct: 96 LHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGL 155 Query: 625 R--SFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 R +P L+Y++SKA++ QFTR +A A G+R Sbjct: 156 RYIGYPH-LSYSVSKAALIQFTRMIAQQYAGSGIR 189 >UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 256 Score = 77.4 bits (182), Expect = 3e-13 Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 2/175 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLT 384 G+V L++ GA + L GR E L+ + D + +++ D+T Sbjct: 9 GRVAVITGGGTGIGRASALVLAEHGADVVLAGRREEPLKATAADVEALGRRAIAVPTDVT 68 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLA 564 K + ++ T+ +G+LDVL+NNAG ET ++ + ++ ++ N+ S +YL+ A Sbjct: 69 KADQCQALVDATLGEFGRLDVLLNNAGGGETKSLMKWTDEEWHEVLELNLSSAWYLSRAA 128 Query: 565 V-PHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P + + KG + + P Y +KA ++ T +A KGVRV Sbjct: 129 AKPMIAQGKGAIVNISSGASLLAMPQAPVYAAAKAGLNNLTGSMAAAWTRKGVRV 183 >UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 249 Score = 77.4 bits (182), Expect = 3e-13 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = +1 Query: 280 GAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 G ++ ++GRN E + V++ + + I AD+T E D+ ++ KT++ +G+LDV V Sbjct: 30 GGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVEDDVRNLVAKTVEAFGRLDVFVA 89 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF- 633 N+G+ G ++DR+++ N++ I+ AV +L+ +G I SF Sbjct: 90 NSGVGSLGDPHEVETEEWDRVLDVNLKGIFLCDKYAVQQMLK-QGQGGAIVNTGSIHSFV 148 Query: 634 --PGVLAYNISKASVDQFTRCVALXLAPKGVR 723 GV AY +K V TR + A +G+R Sbjct: 149 AKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIR 180 >UniRef50_Q2S733 Cluster: Short-chain dehydrogenase of various substrate specificities; n=3; Gammaproteobacteria|Rep: Short-chain dehydrogenase of various substrate specificities - Hahella chejuensis (strain KCTC 2396) Length = 281 Score = 77.0 bits (181), Expect = 5e-13 Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 1/152 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 G + TGRN++ L+KV K ++ L + D+ S E K+ H+G +D+LVNN Sbjct: 30 GENVVATGRNLDALRKVYKPDERL---LLLALDVCSHSQAEDCAKQAAAHFGGVDILVNN 86 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFP 636 AG + G E + + TNV + +T +P++ E + G G F Sbjct: 87 AGYGQLGVFEEVAADKISAQFETNVFGLMGVTRAILPYMREQRQGRIFNISSIGGAIGFE 146 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 G AY +K +V+ F+ C+A + G+ VT+ Sbjct: 147 GASAYCATKFAVEGFSECLAAEVKQFGIGVTI 178 >UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; n=5; Proteobacteria|Rep: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC - Comamonas testosteroni (Pseudomonas testosteroni) Length = 252 Score = 77.0 bits (181), Expect = 5e-13 Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 444 LS+ GA + + N E Q+++ + + L + D++KE+D ++ I G L Sbjct: 25 LSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQLGGLH 84 Query: 445 VLVNNAGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 618 ++VNNAG + ++DR+ N++S+Y+ A+PH + G Sbjct: 85 IVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVNVASTT 144 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+R PG+ Y+ SKA++ T+ +AL A GVR+ Sbjct: 145 GVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRI 180 >UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR precursor - Nocardioides sp. (strain BAA-499 / JS614) Length = 258 Score = 77.0 bits (181), Expect = 5e-13 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 2/179 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITAD 378 F KV L+ GA + + E+ ++ V+ D +++ A+ Sbjct: 6 FDNKVAVITGAGSGIGRAAAELLASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAAN 65 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 + +++E I K + YG L+VL NNAG G++ + + ++R + N + + + Sbjct: 66 VADSAEVEAAIAKVVAEYGGLNVLYNNAGCDSRGSVADATDEDWERAFSVNAKGTFVCSR 125 Query: 559 LAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 AVPHL S G + P AY +K +V TR +A+ LAP+ +RV V Sbjct: 126 AAVPHLTASGGGAIVNQGSVAALVGVPNFAAYCAAKGAVVALTRSMAIDLAPRKIRVNV 184 >UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 264 Score = 77.0 bits (181), Expect = 5e-13 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 2/181 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSIT 372 M+F K V +KLGA + L R E L +++ + +KF +T Sbjct: 1 MDFKNKTVLITGASSGIGKQTAIEFAKLGANIILVARRKEKLDELASELEKFKVTTFVCK 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D++ ++ ++++ K ++ + +DVLVNNAG G++++ S+ + + M TN + Y Sbjct: 61 CDVSDKTQVKEMSKTVLEKFDSVDVLVNNAGFAIYGSVKDLSVDEIESQMETNYFGMMYC 120 Query: 553 TMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 +P +L+ K G PG+ +Y SK ++ F+ + L GV +T Sbjct: 121 IKNFLPSMLDKKSGHIVNVASVAASFGLPGIASYCASKFAILGFSEGLKHELHGTGVGIT 180 Query: 730 V 732 V Sbjct: 181 V 181 >UniRef50_Q8YX01 Cluster: All1418 protein; n=4; Bacteria|Rep: All1418 protein - Anabaena sp. (strain PCC 7120) Length = 277 Score = 76.6 bits (180), Expect = 6e-13 Identities = 48/182 (26%), Positives = 84/182 (46%), Gaps = 2/182 (1%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSI 369 +M+F K + LS+ A L L RN E L++ C + +++ Sbjct: 8 SMSFTNKTIVLTGASAGIGRMLAISLSQQDANLVLAARNQEALEQTMTACTNYPGKVIAV 67 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIY 546 D+T+ +++I++ I +G++D+L+NNAGI + T E T ++ ++++M N Sbjct: 68 HTDVTQAEACQQLIERAIATFGQIDILINNAGIGMLTRFDEVTDISIFEQVMQANYLGAV 127 Query: 547 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 Y T A+P+L S+G G P Y SK ++ F + + L GV V Sbjct: 128 YCTHYALPYLKASQGQLVAISSICGKTGVPTRTGYVASKHAMQGFFDTLRIELHSTGVDV 187 Query: 727 TV 732 V Sbjct: 188 LV 189 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 76.6 bits (180), Expect = 6e-13 Identities = 44/156 (28%), Positives = 79/156 (50%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 441 ++K G + L N E +++ + D K TL ++ ++TK D + +I + +GKL Sbjct: 33 IAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSCNVTKPEDCDSVIAGVKEKFGKL 92 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 618 D LVNNAG+++ S ++D +++ N++ ++ +T A LL+++ G Sbjct: 93 DFLVNNAGVLKDNLFIRMSEQEFDFVLDVNLKGVFLMTKYASKLLLKAESGRIVNISSVS 152 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ PG Y+ SKA V T+ A A + V V Sbjct: 153 GLTGQPGQANYSSSKAGVIALTKVAAREFAGRNVLV 188 >UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=33; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Shewanella oneidensis Length = 254 Score = 76.6 bits (180), Expect = 6e-13 Identities = 53/187 (28%), Positives = 89/187 (47%), Gaps = 6/187 (3%) Frame = +1 Query: 184 SEVTM----NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD--CD 345 SE+TM N GKV L+ GA ++ T + E ++ D Sbjct: 2 SELTMKSSNNLQGKVAFVQGGSRGIGAAIVKRLASEGAAVAFTYVSSEAQSQLLVDEVIA 61 Query: 346 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 525 + ++I AD T+ I + I++T H G LD++VNNAGI+ +IEN +L ++R++N Sbjct: 62 QGGKAIAIKADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVN 121 Query: 526 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXL 705 TNVRS++ + A H+ + F G Y +SK+++ + +A L Sbjct: 122 TNVRSVFVASQEAALHMNDGGRIINIGSTNAERIPFVGGAIYGMSKSALVGLAKGLARDL 181 Query: 706 APKGVRV 726 P+ + V Sbjct: 182 GPRAITV 188 >UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 257 Score = 76.6 bits (180), Expect = 6e-13 Identities = 46/158 (29%), Positives = 85/158 (53%), Gaps = 6/158 (3%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 447 ++ GA L L RN+E + + + K ++ D+ ++ +++ ++ T++ +GK+D+ Sbjct: 32 AEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIGEQDEVKAVVAHTMNRFGKIDI 91 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGI 624 LVNNAGI G +++T L ++D+L +TNVR Y+ T V P + G G+ Sbjct: 92 LVNNAGISWGGELQDTPLKKWDQLYSTNVRGNYFFTTEVVSPMIAGGGGNIINIVSIGGV 151 Query: 625 RSF-PGVL---AYNISKASVDQFTRCVALXLAPKGVRV 726 RS P V+ AY +K ++ T+ ++ A +RV Sbjct: 152 RSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRV 189 >UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 306 Score = 76.6 bits (180), Expect = 6e-13 Identities = 45/126 (35%), Positives = 66/126 (52%), Gaps = 4/126 (3%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLA---QYDRLMNTN 531 +++ D+T DIE++I +D +GKLDVL NNAG TG I + A +D +M N Sbjct: 114 IAVHVDVTSTEDIERMITTAVDRFGKLDVLYNNAGF--TGPIVPLAEAGEDYFDAVMAVN 171 Query: 532 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 708 V+ +Y A+P +L G G+ + G+ Y +K +V Q TR AL A Sbjct: 172 VKGVYLGMKAAIPVMLAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYA 231 Query: 709 PKGVRV 726 KG+RV Sbjct: 232 AKGIRV 237 >UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase SDR precursor - Flavobacterium johnsoniae UW101 Length = 247 Score = 76.6 bits (180), Expect = 6e-13 Identities = 48/179 (26%), Positives = 80/179 (44%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M+F K V K GA + +TGRN ENL+K + + + +I + Sbjct: 1 MDFTNKNVLITGGTTGIGLATAKEFIKAGANVWITGRNSENLEKAANEINS-QKLKTIVS 59 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D SD+ + K ++ LDVL NAGI +IE+ + A +D NTNV+ ++ Sbjct: 60 DTANLSDLSLLEKAFAENNAPLDVLFLNAGIARFTSIEDVTEADFDAQFNTNVKGHFFTL 119 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 +PHL E + G Y+ +K ++++ + A LA + +RV + Sbjct: 120 QKLLPHLAEGSSVIFTSSTVATASNL-GSSIYSATKGALNKIAQIAANELAGRKIRVNI 177 >UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core eudicotyledons|Rep: Similarity to dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 341 Score = 76.6 bits (180), Expect = 6e-13 Identities = 47/151 (31%), Positives = 72/151 (47%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 G ++ T R+ + + ++ KD F L D+ E + K++ K ID +G++DVLVNN Sbjct: 33 GCRVVATSRSQKTMTELEKDSKFFVQEL----DVQSEQSVSKVVSKVIDKFGQIDVLVNN 88 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AG+ G + ++ D NTNV +T VPH+ K I + PG Sbjct: 89 AGVQCIGPLAEIPISAMDYTFNTNVLGSMRMTQAVVPHMASKKKGKIVNIGSISIMA-PG 147 Query: 640 VLA--YNISKASVDQFTRCVALXLAPKGVRV 726 A Y SKA++ T + L L P G+ V Sbjct: 148 PWAGVYTASKAALHALTDTLRLELKPFGIDV 178 >UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein; n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like protein - Streptomyces natalensis Length = 257 Score = 76.2 bits (179), Expect = 8e-13 Identities = 45/178 (25%), Positives = 83/178 (46%), Gaps = 4/178 (2%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 381 +GKV ++ GA + L R V+ L+ + + + A I D+ Sbjct: 9 SGKVSLITGASSGIGAATARLFAREGAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDV 68 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 ++E D+ + ++ T++ YG+LD+ NNAG+ + ++ YD +M TNVR +++ Sbjct: 69 SQEEDVRRAVEFTVEKYGRLDLAFNNAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQ 128 Query: 559 LAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + +L + G G+++ P Y SK +V T+ A AP+G+RV Sbjct: 129 HEISAMLHNGVGGSIVNNSSVAGLQAIPAGAPYIASKHAVIGLTKAAAAEYAPQGIRV 186 >UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 261 Score = 76.2 bits (179), Expect = 8e-13 Identities = 43/155 (27%), Positives = 77/155 (49%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 444 ++K GA + +TGR+ L + + T+ S D+ E ++++ HY ++D Sbjct: 49 VAKEGASVIITGRDEHTLHHAADQIKRDGGTVVSHVCDVRDEDSVDELFAAIHRHYSQID 108 Query: 445 VLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 621 VLVNNAG+ + +++ SL + + TN+ + T A+P ++ Sbjct: 109 VLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLCTRAALP-MMSPGATVVNNVSVAA 167 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +FPG+ AY+ SKA + FT + L P+G+RV Sbjct: 168 NTAFPGMAAYSASKAGLLAFTNTLREELRPRGIRV 202 >UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Roseiflexus|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 264 Score = 76.2 bits (179), Expect = 8e-13 Identities = 41/122 (33%), Positives = 70/122 (57%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 540 ++I DL++ +D E+++ T++ +G+LD+LVNNAGI + + + + ++D L+NTN+RS Sbjct: 80 IAIPGDLSRVADCERVVDATLEQWGRLDLLVNNAGIWGSTPVGSVTEERWDELLNTNLRS 139 Query: 541 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 ++++ A L S G R + Y ISK V TR +A LAP+ + Sbjct: 140 MFFVAQRAADALRASHGVIINIADVGVERPWRNHTPYLISKGGVVTLTRALAKDLAPE-I 198 Query: 721 RV 726 RV Sbjct: 199 RV 200 >UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. ELB17|Rep: Oxidoreductase - Marinobacter sp. ELB17 Length = 252 Score = 76.2 bits (179), Expect = 8e-13 Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEK-IIKKTIDHYGKLDVLVN 456 G +L L GRN ++L++ ++ + A ++ K +++KTI YG LD+LVN Sbjct: 29 GGKLVLAGRNQDSLEETRAGVEQAGGEAIVVAGDVNDAGWRKTVVEKTIQTYGGLDILVN 88 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSF 633 NAG++ G +EN S + + +N+ + LT A+P L +S K G+ Sbjct: 89 NAGVVSAGWLENLSEDDVNTQLQSNLVAPILLTRAALPALRQSPKAAIVNISSIFGLVGM 148 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P Y +KA + F + LA +G+ V Sbjct: 149 PFYATYGATKAGIAHFGEAMRRELADQGIHV 179 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 76.2 bits (179), Expect = 8e-13 Identities = 43/157 (27%), Positives = 83/157 (52%), Gaps = 3/157 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDC--DKFASTLSITADLTKESDIEKIIKKTIDHYGKL 441 L+ G ++ LTGR+ L +V+K +K A + D+T + ++ ++++KT + +G++ Sbjct: 26 LANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIVDVTHKEEVTELVEKTKEKFGQI 85 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 618 D+LVN+AG++ + I + ++ +++ N++ Y +P +L +S G Sbjct: 86 DILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTLYTINAVLPSMLNQSSGHIINIASIS 145 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 G Y+ SKA+V T+ + LA GVRVT Sbjct: 146 GFEVTKKSTLYSASKAAVHSITQGLEKELAKTGVRVT 182 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 75.8 bits (178), Expect = 1e-12 Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 2/141 (1%) Frame = +1 Query: 310 VENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI 486 +++++K+ ++ + SI AD+T + I++++ + +GK+DVL+NNAGII+ G I Sbjct: 33 IDDIEKLREEFSSPQGSFSIEKADVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYI 92 Query: 487 ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISK 663 S ++ ++N N+ ++ T H++ + G GI PG Y+ +K Sbjct: 93 MLMSAKDWNDVINVNLTGVFNCTKAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAK 152 Query: 664 ASVDQFTRCVALXLAPKGVRV 726 V FT ++ LAP +RV Sbjct: 153 GGVIAFTMALSKELAPFCIRV 173 >UniRef50_Q1DAW1 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Myxococcus xanthus DK 1622|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Myxococcus xanthus (strain DK 1622) Length = 275 Score = 75.8 bits (178), Expect = 1e-12 Identities = 50/180 (27%), Positives = 82/180 (45%), Gaps = 2/180 (1%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSI 369 T F G+VV + GA + L R + L+ +++ L + Sbjct: 8 TQPFKGRVVLITGASGGIGRTAARAYAAAGADVVLAARRLPELEDAAREVASLGVRALPV 67 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+T D+ +++++T +G LDVLVNNAG G +E Q ++ NV S++ Sbjct: 68 RCDVTVGDDVTRLVRETDAAFGGLDVLVNNAGQGLYGPLEGVGEEQLRQVFELNVFSLWR 127 Query: 550 LTMLAVPHLLESKGX-XXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +T A+P L + +G G R P + Y SKA+V+ T + LA +G+RV Sbjct: 128 MTREALPLLRKRRGAQVVNVSSVLGHRGLPLLGGYCASKAAVNAMTESLRAELAAEGIRV 187 >UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Firmicutes|Rep: Amino acid adenylation domain - Bacillus cereus subsp. cytotoxis NVH 391-98 Length = 2031 Score = 75.8 bits (178), Expect = 1e-12 Identities = 39/155 (25%), Positives = 79/155 (50%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 444 +++ GA +++ R L + + + K L I D+ + +D++ I+K +GK+D Sbjct: 1805 MAQEGASVAIVSRTEHQLDETACEIRKLGIEPLVIPGDIGEWNDVQHIVKTVSKQFGKID 1864 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 ++VNNAGI + G++ + + ++ ++ NV Y++ +P+L+E K G Sbjct: 1865 IVVNNAGITKVGSVTDVTSEEWKEIIRVNVFGTYHMCRATIPYLIEQKCGKIINIGSDSS 1924 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +P + AY SK V T+ +A + P ++V Sbjct: 1925 FIGYPFMSAYAASKHGVLGLTKSLAEEMKPYNIQV 1959 >UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Flavobacteriaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leeuwenhoekiella blandensis MED217 Length = 246 Score = 75.8 bits (178), Expect = 1e-12 Identities = 44/150 (29%), Positives = 78/150 (52%), Gaps = 1/150 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 G ++ + GRN E ++ + + + + I DL I K+I + + GK+DVLVNN Sbjct: 27 GYKVYIIGRNEEKTRQAADNLGELV--VPIVFDLNNLEAIPKLIDELLQATGKIDVLVNN 84 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR-SFP 636 AGI + A++DR+++TNV+S++ ++ V + + G + P Sbjct: 85 AGINMKKDFAEVTDAEFDRILHTNVKSVFAISREVVKSMKGNYGGSIVNISSMAAQYGIP 144 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRV 726 V+AY SK +++ TR +A+ LA +RV Sbjct: 145 QVIAYTASKTAIEGMTRAMAVDLAQYNIRV 174 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 75.8 bits (178), Expect = 1e-12 Identities = 43/157 (27%), Positives = 84/157 (53%), Gaps = 4/157 (2%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L+ GA++ + N E ++ K ++ + + AD++K D+EK + ++ YG++D Sbjct: 25 LASNGAKVVIVDFNKETGEETLKLVKEQGGEGIFVQADVSKSEDVEKYVNAAVETYGRID 84 Query: 445 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX--XXXXX 615 V NNAG+I+ + + ++YDR+M+ NV+ + +L + V ++E +G Sbjct: 85 VFFNNAGVIQKISPLTEIADSEYDRIMSINVKGV-FLGLKHVIKVMEGQGSGSIINTAST 143 Query: 616 XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+RS + Y+ SK +V T+ +L KG+R+ Sbjct: 144 AGVRSEHSMAVYSASKHAVIGLTKSASLEYVKKGIRI 180 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 75.8 bits (178), Expect = 1e-12 Identities = 54/180 (30%), Positives = 80/180 (44%), Gaps = 1/180 (0%) Frame = +1 Query: 190 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI 369 +T GKV K GA + LTGR+ E Q ++ A I Sbjct: 1 MTNRLQGKVAIITGGTSGIGEATADIYIKEGATVVLTGRSEEKGQAIANRLGDKAHY--I 58 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 AD++KE DI I +T++ +GKLDVL NNAG GTI++ + + ++ + S+ Sbjct: 59 KADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSSVVL 118 Query: 550 LTMLAV-PHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+ P G IR G L Y+ KA+V +T+ + L P G+RV Sbjct: 119 GIRYAIEPMKANGGGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAGVELGPLGIRV 178 >UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillus cereus ATCC 14579|Rep: Short chain dehydrogenase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 260 Score = 75.4 bits (177), Expect = 1e-12 Identities = 41/161 (25%), Positives = 77/161 (47%), Gaps = 2/161 (1%) Frame = +1 Query: 211 KVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTK 387 KVV +L+ G + L+ RN L+ V K + I AD++K Sbjct: 27 KVVVITGASDGIGYETAIYLASKGMIVVLSSRNKTKLESVRKKIHTMGGEAIVIPADISK 86 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 567 ++E++I KTI+ YG++DVL+NNAG++ ++N + + ++ N++ + Y + Sbjct: 87 AKEVEQLINKTIELYGRIDVLINNAGVMPLSWLKNFDIREASSAIDVNIKGVLYGIRYVL 146 Query: 568 PHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTR 687 PH+L +G P + Y+ +K +V+ T+ Sbjct: 147 PHMLTRDEGIIVNIGSTVSYEIPPYGVIYSATKHAVNAITK 187 >UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus thuringiensis Length = 247 Score = 75.4 bits (177), Expect = 1e-12 Identities = 36/122 (29%), Positives = 70/122 (57%), Gaps = 1/122 (0%) Frame = +1 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 ++ AD++K D +++++ ++H+GK+D+LVNNAGI T + + ++R+++ N+ S+ Sbjct: 60 AVQADVSKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSV 119 Query: 544 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 + T +P++ E+ +G G G Y+ +KA + FT+ +AL LA V Sbjct: 120 FNTTSAVLPYITEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLALELAKTNV 179 Query: 721 RV 726 V Sbjct: 180 TV 181 >UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR precursor - Frankia sp. EAN1pec Length = 312 Score = 75.4 bits (177), Expect = 1e-12 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT-AD 378 FAGKVV ++ GA++ GR E ++V ++ + T AD Sbjct: 56 FAGKVVLVTGATSGIGRAAAIAFAREGARVGFCGRREELGRRVEEEIRAAGGEATYTRAD 115 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 + + +E + D YG+LDV +NNAG + ++ ++D +TN R ++ Sbjct: 116 VRDPAQVESFVAGVADRYGRLDVALNNAGTQIVKPLHEMTVEEWDDTAHTNTRGVFLAIK 175 Query: 559 LAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 VP + ES G S PG+ AY+ SK V R AL +RV Sbjct: 176 YEVPPMRESGGGVILVTGSANEFASRPGLGAYSASKGGVTGLVRTAALDYGQDNIRV 232 >UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Streptomyces sp. Tu6071 Length = 244 Score = 75.4 bits (177), Expect = 1e-12 Identities = 45/151 (29%), Positives = 72/151 (47%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA +++TGR+ + ++V K + I A+L ES ++ + + +G++DVLVN Sbjct: 27 GADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGESSARRLAQAAVARFGRIDVLVN 86 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 633 NAG+ G E T+ A +D + NVR Y+L P + G Sbjct: 87 NAGVFPFGPTERTTEADFDAVFGLNVRVPYFLVAELAPAMARRGHGAIVNVTTAAAAYGA 146 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ Y SKA++ T+ A P+GVRV Sbjct: 147 AGLGLYGASKAALVLLTKAWAAEYGPRGVRV 177 >UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 75.4 bits (177), Expect = 1e-12 Identities = 47/184 (25%), Positives = 85/184 (46%), Gaps = 3/184 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 M GKV L++ GA++ + NVE +K +D K L + Sbjct: 1 MRLEGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVE 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYY 549 D+++E +++++T+ +G++DVL NNAGI I G++ + + R NV I++ Sbjct: 61 CDVSREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFW 120 Query: 550 LTMLAVPHLLESKGXXXXXXXX-XGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + A+P + ++ G + G AY SK +V TR +A+ A + +RV Sbjct: 121 CSRYAIPEMRKNGGGRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRV 180 Query: 727 TVSI 738 + Sbjct: 181 NAIV 184 >UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Solibacter usitatus (strain Ellin6076) Length = 249 Score = 75.4 bits (177), Expect = 1e-12 Identities = 44/175 (25%), Positives = 77/175 (44%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 381 F GK + GA++ +TGRN ++ + A + + +D Sbjct: 4 FKGKTALITGGTTGLGLATAKLFIEEGARVIVTGRNPATIKAAQAELGDNA--IVVPSDA 61 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 T D++ + K + +GK+DVL NAG E + A YD ++N N + Y++ Sbjct: 62 TSLPDMDALATKVKETFGKIDVLFVNAGYGHFVPFEAVTEAVYDEMLNLNAKGPYFIVQK 121 Query: 562 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P L+ +++ P + AY +KA++ TR +A L P+G+RV Sbjct: 122 LAP-LMPEGSSVVFTTSIANVKAVPTLSAYGAAKAALRAMTRSIAAELLPRGIRV 175 >UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - unidentified eubacterium SCB49 Length = 256 Score = 75.4 bits (177), Expect = 1e-12 Identities = 38/123 (30%), Positives = 69/123 (56%), Gaps = 3/123 (2%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVRSI 543 I+ DLTKE+D ++K+T++ G LD+L+NNAG ++ + + ++M+ N+ S+ Sbjct: 64 ISGDLTKEADANTLVKQTVEALGGLDILINNAGSLVARKLLSEMETEFWHKVMDINLTSM 123 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIR--SFPGVLAYNISKASVDQFTRCVALXLAPKG 717 ++T A P+L +++ R PG L Y+ SK ++ FTR ++ L +G Sbjct: 124 MFVTRAASPYLAKNENSSIVNLASLAGRKGGHPGSLVYSTSKGAILTFTRALSTELGAQG 183 Query: 718 VRV 726 +RV Sbjct: 184 IRV 186 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 75.4 bits (177), Expect = 1e-12 Identities = 47/181 (25%), Positives = 82/181 (45%), Gaps = 3/181 (1%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSI 369 T +F GKV L+ GA + + + E + K + + + Sbjct: 3 TFDFTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGGEAIFV 62 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 546 D++K D++ ++ +D YGK+D+L+NNAG + + + +D+LM NVR ++ Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122 Query: 547 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +PH++ K G G+ P ++AY SK +V T+ + AP GVR Sbjct: 123 LGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSGVR 182 Query: 724 V 726 V Sbjct: 183 V 183 >UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Desulfococcus oleovorans Hxd3 Length = 266 Score = 75.4 bits (177), Expect = 1e-12 Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 5/154 (3%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA +++ R +ENL V+++ K L + A + + + I+++ + +G++D+LVN Sbjct: 35 GADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGRMDQLPAIVEQVVAEFGQIDILVN 94 Query: 457 NAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 633 NA TI +D ++ N++ +Y+L+ AV ++E KG I F Sbjct: 95 NAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQ-AVARVMEEKGAGGSIINVSSIDGF 153 Query: 634 PG---VLAYNISKASVDQFTRCVALXLAPKGVRV 726 V Y+ISKA V+ TR +AL LAP +RV Sbjct: 154 APQAQVGIYSISKAGVNMATRSMALELAPHKIRV 187 >UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE; n=6; Brucellaceae|Rep: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella melitensis Length = 249 Score = 74.9 bits (176), Expect = 2e-12 Identities = 41/151 (27%), Positives = 82/151 (54%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ L NV+ ++ D ++ +SI AD+++++D+E++ + + +G++D++VNN Sbjct: 30 GARVVLADVNVKRVEDGLADIS--SNGISIQADVSRKNDMERVARTAFEEFGRIDIMVNN 87 Query: 460 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRSF 633 AG + + +D ++ N++++YY T L VP + + G G+ Sbjct: 88 AGFTHRNMPLTDVDEHNFDLIVAVNMKALYYSTQLVVPIMEHQGGGVIINTASATGLHPR 147 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ Y SK+ V T+ +AL LA + +RV Sbjct: 148 KGLTWYCASKSWVVSATKAMALELAERNIRV 178 >UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 245 Score = 74.9 bits (176), Expect = 2e-12 Identities = 46/156 (29%), Positives = 81/156 (51%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLT-GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKL 441 L+K GA + + R+ E +V + ++ T ++I AD++ ++ ++ KT++ YG++ Sbjct: 24 LAKEGATVVVNYARSAEAALEVVQRIEQQGGTAIAIAADVSVPEQVDTLVAKTVETYGRV 83 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 618 DVLVNNAGI + SL + ++N N+ ++ T +L+ K G Sbjct: 84 DVLVNNAGITRDTLLLRMSLEDWQAVINLNLTGVFLCTRAVSKLMLKQKRGRIINIASVA 143 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G PG Y+ +KA V F++ VA LA +G+ V Sbjct: 144 GQMGNPGQANYSAAKAGVIGFSKTVAKELASRGITV 179 >UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 246 Score = 74.9 bits (176), Expect = 2e-12 Identities = 46/179 (25%), Positives = 84/179 (46%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M F + V + GA+L++TGRN E L+ V+++ D L I + Sbjct: 1 MRFRDRCVAILGGNAGIGLAAARLFAAEGAKLAITGRNAETLRAVAEELD----ALCIRS 56 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+ +D E+ +++ D G +DVL NAG+ + + + +D++ + N+R ++ Sbjct: 57 DMGDLNDTERALEEIEDALGGIDVLFVNAGVGGFAMVPDVTPEFWDQIHSVNLRGAFFAI 116 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 A+P L+ G + + PG +AY +KA + R V L P+ +RV + Sbjct: 117 QRALP-LMRDGGSIVITGSIGSMAAVPGNVAYAAAKAGLRAMARIVGKELLPRRIRVNM 174 >UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammaproteobacteria|Rep: Short chain dehydrogenase - Photobacterium profundum 3TCK Length = 662 Score = 74.9 bits (176), Expect = 2e-12 Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 4/177 (2%) Frame = +1 Query: 211 KVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLTK 387 KVV L+ A L L R++E LQ+ D + I ADL+K Sbjct: 379 KVVVLTGASSGIGYTTALKLADTNATLVLIARDLERLQQTRNDVESRGGRAFIYQADLSK 438 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTS-LAQYDRLMNTNVRSIYYLTML 561 E + K++ + H+G +D+L+NNAG I + +T L Y+R M N L + Sbjct: 439 EEESNKVMDEIKRHHGNIDILINNAGRSIRRSVMHSTDRLHDYERTMQINYFGALRLILS 498 Query: 562 AVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 ++P ++E + G + + P AY SK+++D FTR + L +GV T Sbjct: 499 SLPGMVEQQSGHIINLSSVAVLTNQPRFSAYAASKSALDSFTRTASAELCGQGVNFT 555 >UniRef50_Q1VRQ5 Cluster: Short chain dehydrogenase; n=2; Flavobacteriaceae|Rep: Short chain dehydrogenase - Psychroflexus torquis ATCC 700755 Length = 244 Score = 74.9 bits (176), Expect = 2e-12 Identities = 44/157 (28%), Positives = 78/157 (49%), Gaps = 3/157 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGR---NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK 438 L K G +++T R + + KV K + A + I +D+ + EK ++K + +G+ Sbjct: 30 LMKQGVHVAITSRTQSSADQAVKVLKSSNPNAKAIGIESDVRELKHQEKAVQKILSEFGQ 89 Query: 439 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 618 LD ++ NAG+ +IE+ + Q+ ++TN+ +++ +V L +SKG Sbjct: 90 LDYVIANAGMGHYHSIEDLTETQWKETIDTNLTGVFFSIKASVEALKKSKGYFITISSLA 149 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 G F AYN SK + FT+ V + L GV V+ Sbjct: 150 GTNFFAKGSAYNASKFGLTGFTQAVMMDLRDYGVNVS 186 >UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|Rep: Glucose 1-dehydrogenase - Synechococcus sp. (strain CC9311) Length = 265 Score = 74.9 bits (176), Expect = 2e-12 Identities = 43/158 (27%), Positives = 83/158 (52%), Gaps = 5/158 (3%) Frame = +1 Query: 268 LSKLGAQLSLTGRN-VENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 441 + LGA++ + R+ E +++ ++ + ++ + AD++K D++ +I + +GK+ Sbjct: 35 VGSLGAKVVIDYRSHPERTEELIEEVGELGGQSIGVQADVSKLVDLQHLIDTAVQTFGKI 94 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 621 DV+VNNAGI +I +TS +D++MN N+R +++ T A ++ S+G Sbjct: 95 DVMVNNAGIETRTSILDTSPDDFDKVMNVNLRGVFFATQYAAKQMI-SQGSGGRIINISS 153 Query: 622 IRS---FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + P Y ++K V TR + LA KGV + Sbjct: 154 VHEDWPMPNNTPYCVAKGGVRMLTRTAGVELAGKGVSI 191 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 74.9 bits (176), Expect = 2e-12 Identities = 44/155 (28%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLTKESDIEKIIKKTIDHYGKLD 444 L+ G +++L R+ L +V+ + +I AD+T E + + + + YGK+D Sbjct: 27 LAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIFRADVTSEEQVRQAERAILATYGKVD 86 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 621 +L+NNAG+ + ++ ++ R+M+TNV + + + VP + G Sbjct: 87 ILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAAFLMCRSFVPAMSGRGYGRILNMTSIMS 146 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 S PG +AY+ SK ++ TR +AL LAP+G+ V Sbjct: 147 HVSLPGRIAYSTSKTALLGMTRTLALELAPQGITV 181 >UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 268 Score = 74.9 bits (176), Expect = 2e-12 Identities = 41/149 (27%), Positives = 73/149 (48%) Frame = +1 Query: 286 QLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG 465 ++++ GR L V+ + + +D+ K++ + H+G+LD LV NAG Sbjct: 34 RVAICGRRKAPLDAVAAE----TGAVPFVSDVGDPEAARKLVADVVAHFGRLDGLVLNAG 89 Query: 466 IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVL 645 I+ SL +++ + N+ + LT A+PHLL KG G+++ PG+ Sbjct: 90 ILINAPFGEMSLDAWNQQIGINLTGPFVLTQAALPHLLARKGAVVSITSVGGVQTGPGLA 149 Query: 646 AYNISKASVDQFTRCVALXLAPKGVRVTV 732 AY+ SKA + T+ +A A G+R + Sbjct: 150 AYSASKAGLQLMTQALAYEHARDGLRANI 178 >UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 246 Score = 74.9 bits (176), Expect = 2e-12 Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 1/178 (0%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M F GK V + GA++++ +NV L++ + AS I Sbjct: 1 MLFEGKNVIVTGAASGIGRATAIRFAAEGARVTIGDKNVAGLEETAA---MMASAPVIQP 57 Query: 376 -DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D + K+++ + LDVL N +G+++ G E+ SL +D +M N S++ L Sbjct: 58 FDAVDNASCRKLVE--VGARNGLDVLCNISGVLKWGRSEDFSLEDFDLVMRVNTHSVFTL 115 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+PHL+ESKG ++ +AY SK +V T+ +A+ A +GVRV Sbjct: 116 CQAALPHLVESKGNIVNTASAAALQGIAYTVAYVASKHAVAGMTKSLAVEFASRGVRV 173 >UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 253 Score = 74.9 bits (176), Expect = 2e-12 Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 1/150 (0%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ + N+E +KV+++ + ++T E+ + ++ T+ +G+LD+ VNN Sbjct: 31 GARVMIGDINLEQGRKVAEELSSLGDIAFVENNVTAEASCQNAVEHTVKRFGRLDIAVNN 90 Query: 460 AGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 636 AG+I ET + S + R MN N+ +++ V +L + G + P Sbjct: 91 AGVIGETKPLLELSAEGWQRTMNININGVFFGLKAQVNQMLATGGSIINLASIASKIATP 150 Query: 637 GVLAYNISKASVDQFTRCVALXLAPKGVRV 726 Y SK +VD T+ AL A G+R+ Sbjct: 151 SCADYITSKHAVDGLTKAAALDYATMGIRI 180 >UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 260 Score = 74.9 bits (176), Expect = 2e-12 Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 4/179 (2%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITA 375 F GKV L GA + + RN +N+ + + T I Sbjct: 8 FEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAG 67 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 552 + D +K++ T+ +GK+++LVNN GI G I S +D+L NV++ + + Sbjct: 68 HIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQM 127 Query: 553 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 T L PH+ E G +S PG+ AY ++K ++ TR +A+ LA +RV Sbjct: 128 TKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 >UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452; n=30; Bacteria|Rep: Uncharacterized oxidoreductase Lin0452 - Listeria innocua Length = 248 Score = 74.9 bits (176), Expect = 2e-12 Identities = 43/185 (23%), Positives = 86/185 (46%), Gaps = 3/185 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M KV+ L++ GA+L L R VE L+K+ + K +S +I A Sbjct: 1 MTIKNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTI-KASSGEAIFA 59 Query: 376 --DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+TK D +K+++ I+ YGK+D + NAGI+ + +++++++ N++ + Sbjct: 60 KTDVTKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLN 119 Query: 550 LTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +P + K G G++++PG Y +K +V + + A +G + Sbjct: 120 GIAAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNI 179 Query: 727 TVSIL 741 + + Sbjct: 180 RTATI 184 >UniRef50_UPI000023CB35 Cluster: hypothetical protein FG03285.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03285.1 - Gibberella zeae PH-1 Length = 272 Score = 74.5 bits (175), Expect = 2e-12 Identities = 36/126 (28%), Positives = 68/126 (53%), Gaps = 1/126 (0%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 540 L+I D+ + +++ +D +G++DV+VNNAG E ++E+TS + +N N Sbjct: 52 LAIALDVANAQQASETVREAVDKFGRIDVVVNNAGYAEMSSVEDTSFESFHSQVNVNFFG 111 Query: 541 IYYLTMLAVPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALXLAPKG 717 + +T +P + + K G R PG++AY +K +V F+ ++ +AP G Sbjct: 112 VVNVTKAVLPIMRQQKSGHIIQVSTIGDRVGSPGIVAYQSAKWAVAGFSTGLSREVAPFG 171 Query: 718 VRVTVS 735 ++VTV+ Sbjct: 172 IKVTVA 177 >UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 255 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 5/183 (2%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSI 369 T F GK L+ GA + + GR L + + ++ L++ Sbjct: 3 TQRFTGKTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALVEQAGGKALAV 62 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIY 546 TAD+T+ D++ ++ ++H+G LDV VNNAG+ G + + S + ++ NV ++ Sbjct: 63 TADVTRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVF 122 Query: 547 YLTMLAVPHLLESKGXXX---XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 V H+ G + PG AY +KA+V TR AL G Sbjct: 123 LALRAEVRHMRAQPGGGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAALDHIGDG 182 Query: 718 VRV 726 VR+ Sbjct: 183 VRI 185 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 74.5 bits (175), Expect = 2e-12 Identities = 53/177 (29%), Positives = 82/177 (46%), Gaps = 4/177 (2%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADL 381 AGKV +K GA++ + N+E QK V+ D+ + L++ A++ Sbjct: 5 AGKVAVVTGAASGMGQQIAVLFAKEGAKVVVADLNLEAAQKTVALIEDEQGTALAVVANV 64 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ-YDRLMNTNVRSIYYLTM 558 TK+ DIE +I K + YG LD+LVNNAGI++ + +D++ N + T Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124 Query: 559 LAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 A+ H+ E K G G+ AY SK +V FT+ V A K +R Sbjct: 125 KAL-HIFEEKGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVGFQYANKNIR 180 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/179 (26%), Positives = 75/179 (41%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 M KV + GA+L L N E + + S + I Sbjct: 1 MKLQDKVAVITGGVSGIGAATAKLFASEGAKLILVDMNEEKGASIEAELKSQGSEAIFIK 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 AD+T E ++ I ID +GK+D+L NNAGI E + A++ + + ++ ++ + Sbjct: 61 ADVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLV 120 Query: 553 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+ L++ G G PG AYN +KA V TR + L A + +RV Sbjct: 121 AQAAIKEFLKAGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGLEYAARNIRV 179 >UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenase; n=1; Gluconobacter oxydans|Rep: NAD(P)-dependent glucose 1-dehydrogenase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 266 Score = 74.5 bits (175), Expect = 2e-12 Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 4/179 (2%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--ITA 375 FAGK V ++ GAQ++L GR + L V + K + T Sbjct: 9 FAGKKVLVTGASQGIGEATALRFAEEGAQVALNGRKEDKLIAVREKLPKVSGGEHPIATG 68 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D++KE D+++++ ++I G LDVLV NAG E+ L ++ +M NV + Sbjct: 69 DISKEDDVKRLVAESIKAMGGLDVLVCNAGYQIPSPSEDIKLEDFEGVMAVNVTGVMLPC 128 Query: 556 MLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + + LE+ KG I P L Y+ SK +V R +AL A +G+RV Sbjct: 129 REVIRYWLENGIKGTIIVNSSVHQIIPKPHYLGYSASKGAVGNIVRTLALEYATRGIRV 187 >UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Nostocaceae|Rep: Short-chain dehydrogenase/reductase SDR - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 262 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 3/184 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC--DKFASTLSI 369 + GKV + GA++ ++ R+ E ++K + + + A L++ Sbjct: 3 LQLRGKVALVTAASKGLGKATAWQFAHEGAKVVISARS-ELVEKAAAEIASETGAEVLAV 61 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 AD+T+ SDIE++I T++ +G LD+LV NAG +GT + T LA ++ +N N+ S Sbjct: 62 RADVTQPSDIERVINTTVERFGGLDILVTNAGGPPSGTFDETDLATWETAINLNLLSAVS 121 Query: 550 LTMLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 L A+PHL +S + ++ N + V T+ ++ L +RV Sbjct: 122 LVKYALPHLRQSTAPAILTITSTSTKQPVKNLVLSNSIRLGVIGLTKTLSQELGKDQIRV 181 Query: 727 TVSI 738 ++ Sbjct: 182 NSTL 185 >UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia sp. 383|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 261 Score = 74.5 bits (175), Expect = 2e-12 Identities = 45/154 (29%), Positives = 73/154 (47%), Gaps = 1/154 (0%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 L++ GAQ+ + +N V + L + D+ + + + + ++ H+G+LD Sbjct: 29 LAQCGAQVVVAEKNAARADAVRERLGG-RDALFVETDVAEPASVAALFERVDAHHGRLDG 87 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI- 624 LVNNAGI G + SL DRL TN+RS++ LA P + + G Sbjct: 88 LVNNAGITLHGPFDAFSLDDCDRLYRTNLRSMFQCAQLAAPRIARAGGGAIVNIASNHAG 147 Query: 625 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 S PG Y +K + +R +A LAP+ +RV Sbjct: 148 ASVPGFEMYAATKGGIVAMSRAMATSLAPQRIRV 181 >UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 259 Score = 74.5 bits (175), Expect = 2e-12 Identities = 39/175 (22%), Positives = 84/175 (48%), Gaps = 2/175 (1%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKV-SKDCDKFASTLSITADL 381 AGKV + GA++++ R+ + + + S+ D + AD+ Sbjct: 10 AGKVAVVSGGAGGCGGAASELFAAQGAKVAIIDRDGDAAETLASRLRDAGLQAIGFGADV 69 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 +K++++++ + + YG D+L N+AG + + +++D LM NV+S++ +T Sbjct: 70 SKQAEVQQAVNAAREQYGNADILFNHAGTLIVKPFLDIEESEWDWLMGVNVKSMFLMTKA 129 Query: 562 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +P +LE +G + + PG + Y+ +K + F R +A+ +G+R Sbjct: 130 VLPQMLEKGRGSIVCTSSISAVCATPGEVLYDATKGACHMFARAIAVEYRDRGIR 184 >UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Roseovarius sp. 217 Length = 256 Score = 74.5 bits (175), Expect = 2e-12 Identities = 44/156 (28%), Positives = 79/156 (50%), Gaps = 2/156 (1%) Frame = +1 Query: 265 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 FLS+ GA+++L +V++L + D L+I AD++ D ++ + +T++ +G++D Sbjct: 26 FLSE-GAKVALVDLHVDDLSDAAGDLGNPDDLLTIAADVSSVEDCKRYVAQTVEKFGRID 84 Query: 445 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 618 V NNAG+ + + + +DR+M NVR + +P + + G Sbjct: 85 VFFNNAGVEGMVAPLVDQKIEDFDRVMAVNVRGAFLGLQHVLPVMTGQQSGSVINMSSIA 144 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G++ P V Y SK +V TR A+ +A VRV Sbjct: 145 GLKGSPNVAPYITSKHAVVGLTRAAAIEVAGHNVRV 180 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 74.5 bits (175), Expect = 2e-12 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 3/180 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 372 M KV +K GA++ +T N ++ + D F L + Sbjct: 4 MRLENKVAVITGGGTGIGKETALLFAKEGAKIVITDINEQSGNETVSDIQAFGGEALFVL 63 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 D++ E D +K+ + I + K+D+L NNAGI + L+ ++RLM+ NV + +L Sbjct: 64 HDVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGV-FL 122 Query: 553 TMLAVPHLL--ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 M + L+ ++KG G+ G + Y SK +V T+ A+ AP GVRV Sbjct: 123 GMKHIMPLMAKQNKGSVINASSIAGLTGAAGHVLYGASKGAVRIMTKDAAMEYAPYGVRV 182 >UniRef50_A1ZFM2 Cluster: Oxidoreductase; n=1; Microscilla marina ATCC 23134|Rep: Oxidoreductase - Microscilla marina ATCC 23134 Length = 264 Score = 74.5 bits (175), Expect = 2e-12 Identities = 37/118 (31%), Positives = 65/118 (55%), Gaps = 1/118 (0%) Frame = +1 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+T E++I + +K+ I++ G +DVLVNNAG+ G +E T L+ +++ TNV + LT Sbjct: 48 DITNETEIVQGVKQVIENEGHIDVLVNNAGLGTAGALEETPLSDIEQVFATNVMGVVRLT 107 Query: 556 MLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +P++ + G G+ P Y SK ++D T + + +AP G++V Sbjct: 108 QEVLPYMRKQQSGKIINIGSIGGVMGLPYRATYCASKFAIDGLTEALRMEVAPFGIQV 165 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 74.5 bits (175), Expect = 2e-12 Identities = 46/183 (25%), Positives = 85/183 (46%), Gaps = 3/183 (1%) Frame = +1 Query: 187 EVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFA-ST 360 EV + GKV+ +K AQ+ + ++ + + + + S Sbjct: 4 EVILMLNGKVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITALGHSA 63 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 540 ++I AD+T E +++++ ++ + YG+LD+LVNNAGI++ + T + +Y +M+ N + Sbjct: 64 MAIRADVTCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKG 123 Query: 541 IYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 + T A ++ K G G+ G AY SK+ V FT+C A L Sbjct: 124 TFLCTQHAAKIMVRQKAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAKELGAFN 183 Query: 718 VRV 726 + V Sbjct: 184 ITV 186 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 74.5 bits (175), Expect = 2e-12 Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 5/153 (3%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 456 GA++ + GR E Q V + K S D+T + IEK+I T + YGK+D+LVN Sbjct: 32 GAKVVICGRREEKGQAVVDNITKEGGESSYHFFDITNTNSIEKLIDDTAEKYGKIDILVN 91 Query: 457 NAG--IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGI 624 NA ++ G I+ ++ +D + +++R +Y T +P+L E+ G Sbjct: 92 NAANVALKDGNIDELTIDMWDAIFESDLRGTFYATKCVIPYLQKNENGGSIINIGSMASC 151 Query: 625 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 G AY +K+ VD FT+ AL +R Sbjct: 152 GGDLGSTAYACAKSGVDMFTQYTALQYGKDNIR 184 >UniRef50_Q7NK97 Cluster: Gll1581 protein; n=1; Gloeobacter violaceus|Rep: Gll1581 protein - Gloeobacter violaceus Length = 218 Score = 74.1 bits (174), Expect = 3e-12 Identities = 45/155 (29%), Positives = 81/155 (52%), Gaps = 1/155 (0%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 L++ G ++L R+ E L+++ + A T+++ DLT + ++ G +DV Sbjct: 5 LAEQGFGVALVARSRERLEQLQSELAP-AKTVALAQDLTDFGAADGVVAAVQTKLGPIDV 63 Query: 448 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGI 624 LVN+AG+ T T+E T +A ++R++ N+ + + +T +P + G G Sbjct: 64 LVNSAGMAYTNTLEGTPVADWERVLALNLTAPFAMTRAVLPGMRARRSGLVVNLVSIAGE 123 Query: 625 RSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 R+F G AY SKA + TR +A + +G+RVT Sbjct: 124 RAFAGWGAYCASKAGLLAMTRVLAEEVRSEGIRVT 158 >UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Lactobacillus reuteri 100-23 Length = 246 Score = 74.1 bits (174), Expect = 3e-12 Identities = 40/157 (25%), Positives = 80/157 (50%), Gaps = 4/157 (2%) Frame = +1 Query: 274 KLGAQLSLTGRNVENLQKVSKDCDKF---ASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 K G L GR+ E +V + + A + I AD++K S++E + + T++ + +D Sbjct: 23 KNGWNTVLIGRDAEKGMQVERQLGETYSPAQVVFIQADISKSSEVEHVKQITLNKFKTVD 82 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 621 +VNNAGI+ G + TS ++++ + +V+ + ++ +P ++E G G Sbjct: 83 AIVNNAGIVIHGEVHETSEEDWNKIFDVDVKGTFLISKAFLPTMIEQDHGSIVNISSVSG 142 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 + ++AYN +K ++ TR +A+ +RV V Sbjct: 143 MAGDRAMVAYNAAKGAIINMTRAMAIDYGKNNIRVNV 179 >UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 255 Score = 74.1 bits (174), Expect = 3e-12 Identities = 37/127 (29%), Positives = 70/127 (55%), Gaps = 2/127 (1%) Frame = +1 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 ++ D+T + I++++++TID YG++DVLVNN G+ G + + + +DR + N++S+ Sbjct: 55 ALLCDVTDPASIDRVVRETIDAYGRIDVLVNNVGVSAPGGVVDMTEEIWDRQFDINLKSV 114 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALXLAPKG 717 + + +P + +G + G +AY+ SKA++ QFTR AL + Sbjct: 115 FLMCKAVLPLMDRQRGGNVVNVSSLSALRYSGKPQIAYSASKAALIQFTRMAALMHSEHN 174 Query: 718 VRVTVSI 738 VR+ I Sbjct: 175 VRLNCVI 181 >UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Herpetosiphon aurantiacus ATCC 23779 Length = 257 Score = 74.1 bits (174), Expect = 3e-12 Identities = 43/181 (23%), Positives = 86/181 (47%), Gaps = 3/181 (1%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSI 369 T + +GKV ++ GA++ + R +E+LQ V+ ++ T L++ Sbjct: 3 TFDLSGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAM 62 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 546 K ++ ++ +T+ +G++D++VNNA G + N+ +Q+D+ NV+ + Sbjct: 63 ACHTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYF 122 Query: 547 YLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +L A + + G G++ + Y+ISKA+V T+ +A L P +R Sbjct: 123 WLIQAAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIR 182 Query: 724 V 726 V Sbjct: 183 V 183 >UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|Rep: FabG3_1 - Roseovarius sp. HTCC2601 Length = 249 Score = 74.1 bits (174), Expect = 3e-12 Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 1/178 (0%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M+ GKVV ++ GA + L + ++ +++D A L++ Sbjct: 1 MDVTGKVVLISGAARGMGAHEARRFAEAGACVILGDVLDDEVRALAEDLGD-ARALAVPL 59 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+++ D E + + +G++DVLVNNAGI+ IE S +++++++ N+ + Sbjct: 60 DVSRSEDWEGAVAAGVARFGQIDVLVNNAGILRFSNIETCSDEEWEKVLSINLGGAFKGI 119 Query: 556 MLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +P + + G G+++F GV AY SK + TR A+ LA G+RV Sbjct: 120 RAVLPVMKRNGSGSIINISSTAGLKAFGGVSAYVTSKFGIRGLTRAAAVELAGHGIRV 177 >UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep: Dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 254 Score = 74.1 bits (174), Expect = 3e-12 Identities = 41/152 (26%), Positives = 81/152 (53%), Gaps = 3/152 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 456 G ++++ + +K ++ DK + L + D++ ES +E ++K +G++D+LVN Sbjct: 35 GMKVAILSVGEGSAKKAAESIDKSGTGALGLQCDVSDESSVELALEKINSLFGRIDILVN 94 Query: 457 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR--S 630 +AGI++ +IE + +D++++TN+R + ++ +L +SK R Sbjct: 95 SAGILDMSSIEEMTTEHWDKVLSTNLRGTFTTIQKSIKYLEKSKFPRIINISSNSGRMGG 154 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 F +AY+ SK + T +A LAPKG+ V Sbjct: 155 FENGMAYSASKGGIIALTYGLARKLAPKGITV 186 >UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductase; n=1; Microscilla marina ATCC 23134|Rep: 3-oxoacyl-acyl-carrier-protein reductase - Microscilla marina ATCC 23134 Length = 253 Score = 74.1 bits (174), Expect = 3e-12 Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 2/156 (1%) Frame = +1 Query: 265 FLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGK 438 FL++ GA++ +TGR+ E L+ +++ K + L+I AD + +K+ + D +GK Sbjct: 26 FLAE-GAKVVVTGRSDEKLKATNEELAKIHANHFLTIKADAADVTSNKKVFEAAQDKFGK 84 Query: 439 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 618 +D+L NAG+ + + + A YD +MNTN++ ++L +P+ E Sbjct: 85 VDILFANAGVGRFMPLSDVTEAMYDEVMNTNLKGPFFLVQAGLPYFNEGASIILNTSVSN 144 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + PG AY SKA + R A L+ +RV Sbjct: 145 QM-GMPGASAYAASKAGLRLLARVFAAELSAHKIRV 179 >UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 248 Score = 74.1 bits (174), Expect = 3e-12 Identities = 50/181 (27%), Positives = 85/181 (46%), Gaps = 5/181 (2%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQL---SLTGRNVENLQKVSKDCDKFASTLSI 369 N +GKV L++ GA + +TG+ E ++V K +++ Sbjct: 3 NLSGKVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENEVAEEVRK---LGGQGMAL 59 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+T E++ + D YG +D+LVNNAGI + + R++N N+ ++ Sbjct: 60 RLDVTDGKMAEEVARTVFDKYGHIDILVNNAGIYPFKPFMEMTFNDWYRVINVNLNGVFN 119 Query: 550 LTMLAVPHLLESK-GXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +T VP++++ K G G + F G+ Y+ SKA + FTR +AL LA G+ Sbjct: 120 VTRAVVPYMVKQKNGRIINIASIAGAVMGFMGLTHYSASKAGIVGFTRALALELARYGIT 179 Query: 724 V 726 V Sbjct: 180 V 180 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 74.1 bits (174), Expect = 3e-12 Identities = 51/174 (29%), Positives = 79/174 (45%), Gaps = 2/174 (1%) Frame = +1 Query: 211 KVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSITADLTK 387 KVV L++ GA + L+ N E Q V++ + + D+T Sbjct: 7 KVVLVTGGAMGMGLTHCTLLAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTN 66 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 567 E+ + + +LD LVNNAGI+ +++TS ++DR+ NVRS++ T + Sbjct: 67 ENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVI 126 Query: 568 -PHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P KG G+ PG AY SK +V FT+ A+ LAP +RV Sbjct: 127 EPMRKAHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRV 180 >UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=4; Bacteria|Rep: Predicted short chain dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 250 Score = 73.7 bits (173), Expect = 4e-12 Identities = 38/149 (25%), Positives = 77/149 (51%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA+++ GRN E L ++ +++ D T D+++++ +T+ +G +D++V N Sbjct: 31 GAKVAAFGRNTEALDALA--AAHAGKVVTVKGDATCAEDLQRLVDETLKAFGGVDIVVPN 88 Query: 460 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 639 AGI + E+++ ++ + N+ + L +PH+ + FPG Sbjct: 89 AGIARVVSFEDSTREAFETQFSVNLFAAAETVRLFLPHIRRGGSVQFITTFLTQV-GFPG 147 Query: 640 VLAYNISKASVDQFTRCVALXLAPKGVRV 726 + Y+ SKA++ F + +A LAP+G+RV Sbjct: 148 LAIYSASKAALKSFAQTLAAELAPRGIRV 176 >UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rhodobacteraceae|Rep: Short-chain dehydrogenase/reductase SDR - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 259 Score = 73.7 bits (173), Expect = 4e-12 Identities = 37/120 (30%), Positives = 62/120 (51%) Frame = +1 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 +I AD + + + +D G+LDVLVNNAG+++ +E +LA ++R + N+ + Sbjct: 46 AIAADFADADAPARAVAEAVDRAGRLDVLVNNAGVMQEARVEEMALADWERTIRVNLTAP 105 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 + A+PHL +G G+ + P AY SKA + TR VA+ +G+R Sbjct: 106 FLAIRAALPHLRAVRGAIVNVGSIEGLGANPRHAAYCASKAGLHGLTRAVAVDHGAEGIR 165 >UniRef50_Q1NHB1 Cluster: Oxidoreductase; n=1; Sphingomonas sp. SKA58|Rep: Oxidoreductase - Sphingomonas sp. SKA58 Length = 260 Score = 73.7 bits (173), Expect = 4e-12 Identities = 45/151 (29%), Positives = 75/151 (49%), Gaps = 1/151 (0%) Frame = +1 Query: 286 QLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG 465 ++ L R+ NLQ V+ A+T + DL + ++I+ + H +D +++NAG Sbjct: 31 RMLLADRDAANLQVVADAVGPAAATCVV--DLAEPDCGDRIVAAALAHMDGIDAVISNAG 88 Query: 466 IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVL 645 II G + ++ +DR+ N RS + L A PHL ESKG + P + Sbjct: 89 IIMGGALVELPISDFDRIFAINTRSSWLLGKAAHPHLKESKGAFVATASMSATQPTPALG 148 Query: 646 AYNISKASVDQFTRCVALXLAPKGVRV-TVS 735 Y+ SKA++ R +++ P G+R TVS Sbjct: 149 FYSSSKAALLMMIRQLSIEWGPDGIRCNTVS 179 >UniRef50_Q1ASB7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 235 Score = 73.7 bits (173), Expect = 4e-12 Identities = 39/175 (22%), Positives = 88/175 (50%), Gaps = 2/175 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLT 384 GKV ++ GA+L++ R E+++ V+++ + A L++ AD++ Sbjct: 4 GKVALVTGASQGLGRALALAYAQAGARLAINARREESIRPVAEEIARAGAQVLAVAADVS 63 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTML 561 + D+ + + + ++ +G++D+LVNNAG++ I ++ R+++ N+ + ++ Sbjct: 64 RSEDVGRFVGEAVERFGRIDILVNNAGLLGPRVPIVEYPEEEWRRVIDVNLTGAFLVSKA 123 Query: 562 AVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+PH + + P AY++SK ++ T+ +A L +G+RV Sbjct: 124 AIPH-MPPGSSIINVVSGVSVEGRPRWGAYSVSKFGLEGLTQILAAELKDRGIRV 177 >UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 282 Score = 73.7 bits (173), Expect = 4e-12 Identities = 42/178 (23%), Positives = 83/178 (46%), Gaps = 3/178 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITAD 378 F GKV ++ GAQ+++T R E L+++ + + + ++I D Sbjct: 38 FNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCD 97 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLT 555 ++ D+ + +T++ +G+LD NNAG+ + + +L ++DR+++ N+R + Sbjct: 98 VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVCM 157 Query: 556 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + +L + G GIR G +Y SK ++ T+ AL A +RV Sbjct: 158 KHEIAQMLRQGGGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRV 215 >UniRef50_A1UJQ6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 246 Score = 73.7 bits (173), Expect = 4e-12 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 8/185 (4%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE------NLQKVSKDCDKFAS 357 M+ AGKV L+ GA +++ R+ + + V++ Sbjct: 1 MSLAGKVAFVAGASRGIGATVAKALAAEGAAVAVAARSEQPGKLPGTIHTVAESITASGG 60 Query: 358 -TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 534 L ++ D+T ES +E + +T+ +G +D+LV NAG++ G IE+T L ++ +N N+ Sbjct: 61 RALPVSCDVTDESSVETAVAETVSEFGGIDILVANAGVLWLGPIESTPLKRWQLCLNVNL 120 Query: 535 RSIYYLTMLAVPHLLESKGXXXXXXXXXGI-RSFPGVLAYNISKASVDQFTRCVALXLAP 711 ++ +T +PH+ G G+ + G AY +SKA+ ++ +A L Sbjct: 121 TGVFLVTKAVIPHVRARGGGSLIAVTTTGVTMTDQGSNAYWVSKAAAERLYLGLAADLRA 180 Query: 712 KGVRV 726 + V Sbjct: 181 DNIAV 185 >UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - marine gamma proteobacterium HTCC2080 Length = 248 Score = 73.7 bits (173), Expect = 4e-12 Identities = 38/126 (30%), Positives = 66/126 (52%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 540 ++I AD++ + + + +TI +G++DV+VNNAG+ G +E S + ++N N+ Sbjct: 56 IAIQADVSDVAAAQSAVDETIATFGRIDVVVNNAGVHRGGKVERLSPEDWQTVLNVNLTG 115 Query: 541 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 + A PH + S G R FPG +AY SKA + T +A+ +A +G+ Sbjct: 116 ALNMIRAAKPH-MGSGSSIINIGAVVGFRGFPGDVAYASSKAGLSGMTNALAIEMAKQGI 174 Query: 721 RVTVSI 738 V + I Sbjct: 175 TVNLVI 180 >UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 253 Score = 73.7 bits (173), Expect = 4e-12 Identities = 38/126 (30%), Positives = 69/126 (54%), Gaps = 4/126 (3%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVR 537 ++ + D+T +E ++K D +G+LD+L+NNAGI + +++ + ++ + N N + Sbjct: 54 VTFSVDVTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQK 113 Query: 538 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG---VLAYNISKASVDQFTRCVALXLA 708 +Y+ +LA +++G + + YN+SKA+VD T+C AL LA Sbjct: 114 GVYH-GILAGGRQFQAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAALELA 172 Query: 709 PKGVRV 726 P GVRV Sbjct: 173 PLGVRV 178 >UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Trichocomaceae|Rep: 3-ketoacyl-acyl carrier protein reductase - Aspergillus fumigatus (Sartorya fumigata) Length = 256 Score = 73.7 bits (173), Expect = 4e-12 Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 10/187 (5%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS------ 357 M+ GK+ L+K GA L+L + + Q +++ CD+ S Sbjct: 1 MSLRGKIAIVTGASRGIGAGIALDLAKQGANLTLIYTSASSDQAINQLCDQIHSLNNGST 60 Query: 358 TLSITADLTKESDIEKIIKKTIDHY----GKLDVLVNNAGIIETGTIENTSLAQYDRLMN 525 + + ADL +I+ T D + K+D+LVNNAG+ + +T+ + + Sbjct: 61 AIKVQADLRHSDAPAQILAATFDAFPNANNKIDILVNNAGVSLCKNLADTTDHDISSVFD 120 Query: 526 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXL 705 NV + +T +PH L + G R PG Y+ SKA+V+ FTR +A L Sbjct: 121 INVYGLISMTRAVIPH-LRAPGRIINLSSVAARRGSPGFSVYSASKAAVEGFTRSLACEL 179 Query: 706 APKGVRV 726 P G V Sbjct: 180 GPVGCTV 186 >UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family member 7 precursor; n=25; Euteleostomi|Rep: Dehydrogenase/reductase SDR family member 7 precursor - Homo sapiens (Human) Length = 339 Score = 73.7 bits (173), Expect = 4e-12 Identities = 49/153 (32%), Positives = 71/153 (46%), Gaps = 6/153 (3%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 432 LSKLG L L+ R V L++V + C K L + DLT E K + + Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129 Query: 433 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 609 G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189 Query: 610 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 708 GI S P + Y SK ++ F + LA Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELA 222 >UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=18; Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 255 Score = 73.3 bits (172), Expect = 6e-12 Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 5/178 (2%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 387 GKV L+ GA ++ GR+ + + + LSI AD + Sbjct: 9 GKVALITGANTGIGQGIAIALAAAGADIAAAGRSAPTETQAAVEA-LGRKFLSIKADFSS 67 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 567 +++++ +T+ +GK+D+LVNNAGII S A +D +M+TN++ +++LT Sbjct: 68 IEPVQRVVDETVAAFGKVDILVNNAGIIRRADSIEFSEADWDAVMDTNLKVVFFLTQAFA 127 Query: 568 PHLLES--KGXXXXXXXXXGIRSFPG---VLAYNISKASVDQFTRCVALXLAPKGVRV 726 L+ +G + SF G V +Y SK+ + T+ +A A KG+ V Sbjct: 128 KQALKQGFEGGQAKVINIASLLSFQGGIRVPSYTASKSGLAGLTKILANEWATKGINV 185 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 73.3 bits (172), Expect = 6e-12 Identities = 42/156 (26%), Positives = 85/156 (54%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTG-RNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 441 L+K G +++T ++ ++ ++V ++ K L+I D++K ++EK ++K I+ +G + Sbjct: 25 LAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSKYHEVEKAVEKVIEEFGSI 84 Query: 442 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 618 DV+VNNAGI + I ++D++++ N++ + + A ++++ KG Sbjct: 85 DVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIKKRKGKIINISSVV 144 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ G Y SKA + T+ VA LA +G+ V Sbjct: 145 GLMGNVGQANYAASKAGIIGLTKSVAKELASRGITV 180 >UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebacterium glutamicum|Rep: Putative oxidoreductase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 73.3 bits (172), Expect = 6e-12 Identities = 44/182 (24%), Positives = 84/182 (46%), Gaps = 1/182 (0%) Frame = +1 Query: 184 SEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL 363 + T GKV L+ GA++ +T N E Q++ K+ + + Sbjct: 29 THTTKRVEGKVAFITGAASGMGASHARVLAAHGAKVVITDLNDELGQELVKEIGEEKAHY 88 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 + ++T + E ++K ++ +GK+D L+NNAGI +G++E+ + A +D+ + ++ Sbjct: 89 -VHLNVTSFEEWEVAVQKALERFGKIDTLINNAGIFSSGSVEDATAADWDKTIAIDLNGT 147 Query: 544 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 +Y A+P L E+ G+ F AY+ +K V T+ A+ L + Sbjct: 148 FYGMKAALPALKENPTASIINISSIAGVTGFKNRAAYSAAKWGVQGLTKTSAMDLGKYNI 207 Query: 721 RV 726 RV Sbjct: 208 RV 209 >UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 262 Score = 73.3 bits (172), Expect = 6e-12 Identities = 42/183 (22%), Positives = 84/183 (45%), Gaps = 5/183 (2%) Frame = +1 Query: 193 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLS 366 + + GKV + G L++T R + ++++KD + L Sbjct: 9 SFDLTGKVAIVTGGTKGIGYAVAATFAMYGCDLAITSRTPADCERIAKDIETLYGVKCLG 68 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSI 543 I+AD + + DI++++ +T++ +GK+D+L+NNAGI +T + + + + ++NTN++ + Sbjct: 69 ISADSSNKDDIDRVVAQTVETFGKIDILINNAGISGKTAALLDQTEDDFMNVINTNLKGV 128 Query: 544 YYLTMLAVPHLLE--SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 + + + G G+ V Y SKA V T+ +A A G Sbjct: 129 FQFAQAVAAQIAKQGKGGRIVNIASVGGLIGGKSVAPYGASKAGVLSLTKTMANEWARYG 188 Query: 718 VRV 726 + V Sbjct: 189 ITV 191 >UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep: Putative oxidoreductase; short-chain dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 297 Score = 73.3 bits (172), Expect = 6e-12 Identities = 50/181 (27%), Positives = 83/181 (45%), Gaps = 4/181 (2%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITAD 378 FAG VV + GA + + R ++ ++ ++ S + D Sbjct: 36 FAGTVVLVTGAGRGLGRTIAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGD 95 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 L + +D+ + + + +G LDV+V++A G + D L+ +NV +++++T Sbjct: 96 LAERADVATMFDEAVARHGALDVVVHSAADNAQGLLAEIDDDTLDYLLRSNVHALHWITR 155 Query: 559 LAVPHLLESK--GXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 AVPHL SK G R F PG+ AY +KA ++ F R +A L P GVRV Sbjct: 156 AAVPHLTRSKLPGRMIFISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVN 215 Query: 730 V 732 V Sbjct: 216 V 216 >UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1 Length = 263 Score = 73.3 bits (172), Expect = 6e-12 Identities = 45/126 (35%), Positives = 68/126 (53%), Gaps = 3/126 (2%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSI 543 +TAD+ E D+E +++ + YG+LD NNAG + IE T+ +YD +M TNVRS Sbjct: 60 VTADVLSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTN-DEYDTVMATNVRSA 118 Query: 544 YYLTMLAVPHLLESKGXXXXX-XXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 ++ + +L G +R+ PG+ AY+ SKA + TR VA+ A K + Sbjct: 119 FWCMKYQLKAMLAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNI 178 Query: 721 RV-TVS 735 R TVS Sbjct: 179 RANTVS 184 >UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 254 Score = 73.3 bits (172), Expect = 6e-12 Identities = 44/158 (27%), Positives = 83/158 (52%), Gaps = 4/158 (2%) Frame = +1 Query: 271 SKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDV 447 +K GA+L++ R E L++V +D ++ A L++ AD++ + D+++ + T YG++DV Sbjct: 37 AKEGAKLAICARGEEKLKEVQRDLERIGAEVLAVAADVSNQRDVDRFVSITEGVYGRVDV 96 Query: 448 LVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 618 L+NNA + G + + +++ ++ NV + +T +P +L G Sbjct: 97 LINNASVFGKGPCLLLDYLNEEFEDVLRVNVMNTLMMTKRVLPGMLSRGGGSVINLTSEA 156 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 G F AY ISK +V+ T+ A L+ GVR+ + Sbjct: 157 GKTGFAEWGAYGISKFAVEGMTQTWADELSETGVRMNM 194 >UniRef50_A5FER5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 268 Score = 73.3 bits (172), Expect = 6e-12 Identities = 44/157 (28%), Positives = 77/157 (49%), Gaps = 1/157 (0%) Frame = +1 Query: 265 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 FL+K G ++ T RNV+ L + + + TL + D +ES +++K +H+G +D Sbjct: 22 FLTK-GYNVAATARNVDTLNDLKEKYGQSVLTLKLDVDNREES--LSVVEKVQNHFGSID 78 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 +L+NNAG TG IE + + TN +LT +P + K G G Sbjct: 79 ILINNAGYALTGAIEEATPNEARAQFETNFFGTLWLTQAVLPIMRNQKSGHIIQVSSILG 138 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 + + P + YN SK +++ + +A + G+ VT+ Sbjct: 139 LAALPTMGLYNASKFAIEGLSETLAAEVKQFGINVTL 175 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 73.3 bits (172), Expect = 6e-12 Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 2/179 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 ++F GKVV ++ GA++ + + + V + + L + Sbjct: 5 LDFTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAETVRLIEESGGTALFVRT 64 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 552 D+T +D++++++ T+D YG L V NNAGI+ TG + S +DR + +++ ++ Sbjct: 65 DVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFDRTIAVDLKGVFLA 124 Query: 553 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + H+ + G G+ + PG+ Y +K V TR A+ A GVRV Sbjct: 125 LKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAIDYAAAGVRV 183 >UniRef50_UPI0000E49977 Cluster: PREDICTED: similar to dehydrogenase/reductase (SDR family) member 7; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to dehydrogenase/reductase (SDR family) member 7 - Strongylocentrotus purpuratus Length = 344 Score = 72.9 bits (171), Expect = 7e-12 Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 6/184 (3%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST-----L 363 N G+VV L++ GA++ L+ R V L++V +C +F L Sbjct: 64 NMMGRVVWITGASSGIGEELAYQLARKGAKVVLSARRVNELERVRGNCVRFPEVREENIL 123 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 + D TK ++ + +D YGK+D+L+NN+G + +++ + +M+ N+ Sbjct: 124 VLPMDATKYETHGQVAETIVDRYGKIDILINNSGRSQRALVQDCKIEVDKAIMDLNLMGP 183 Query: 544 YYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 L +A+P++LE+ G GI P AY SK + F V L+ + + Sbjct: 184 ISLFKVALPYMLENNYGQIINISSATGIMPAPLSSAYCASKHGMHGFFNSVRSELSHRNI 243 Query: 721 RVTV 732 VT+ Sbjct: 244 AVTM 247 >UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacteria|Rep: SHORT-CHAIN DEHYDROGENASE - Brucella melitensis Length = 269 Score = 72.9 bits (171), Expect = 7e-12 Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 4/177 (2%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQ-LSLTGRNVENLQKVSKDCDKF-ASTLSITADL 381 GK+ ++ GAQ L + GR+ E + + ++ A + + DL Sbjct: 7 GKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAVFVQVDL 66 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 561 K D +I+ + +G+LD+LVN AG+ + GTI +TS +DRL N R+ ++L Sbjct: 67 EKVEDCRRIVAEADRAFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAPFFLIQE 126 Query: 562 AVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A+ + G + P + AY SK ++D TR VA + +RV Sbjct: 127 AIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCASKGALDTLTRNVAYSVLRNRIRV 183 >UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 255 Score = 72.9 bits (171), Expect = 7e-12 Identities = 48/177 (27%), Positives = 81/177 (45%), Gaps = 2/177 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 381 F KVV + GA+L+L E L+K + + + L ITA++ Sbjct: 2 FKDKVVLITGAAGGIGLEAAKAYAHEGAKLALVDLKNEALEKAASEIET-EEILLITANV 60 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY-LT 555 KE D++ + +T + YGK+D+ +NNAGI + I + + + + NV +++ + Sbjct: 61 GKEEDVKNYVDRTKEQYGKIDIFINNAGINGQFKNIIEQTKENFSNVFDVNVMGVFFGMK 120 Query: 556 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + L+ G G+ PG+ AY SK +V + AL +A GVRV Sbjct: 121 YVLQVMKLQKSGVVINTASNGGLLGAPGMSAYVASKHAVIGLNKTAALEMAEYGVRV 177 >UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetella|Rep: Putative oxidoreductase - Bordetella parapertussis Length = 262 Score = 72.9 bits (171), Expect = 7e-12 Identities = 44/178 (24%), Positives = 83/178 (46%), Gaps = 4/178 (2%) Frame = +1 Query: 205 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVS-KDCDKFASTLSITADL 381 AG+V + GA L+L R + +++++ + C + + + AD+ Sbjct: 15 AGRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAADV 74 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIYYLT 555 T + + + +++ ++H+G++D L N AG G ++ LA ++R + ++ S Sbjct: 75 TDDDSVRQAVRRAVEHFGRIDTLFNCAGGSVAGDTAVDKVDLALWNRTLRLDLDSTMLCC 134 Query: 556 MLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 AVP ++ + G G+R G AY +K +V TR +A AP GVRV Sbjct: 135 RHAVPAIVRAGGGAVVNMSSGAGLRGSFGGHAYTAAKGAVIALTRALAAEYAPHGVRV 192 >UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14; cellular organisms|Rep: Short-chain alcohol dehydrogenase - Zymomonas mobilis Length = 248 Score = 72.9 bits (171), Expect = 7e-12 Identities = 40/183 (21%), Positives = 80/183 (43%), Gaps = 2/183 (1%) Frame = +1 Query: 190 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLS 366 + N K+V LS LGA + L R E + ++ K L+ Sbjct: 1 MNQNIRNKIVVITGASSGLGAETARHLSDLGATVVLGARREERIATLANSIVAKGGQALA 60 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 546 I D+T ++ ++ + YG++DVL+NNAG++ +E + +++ +++ N++ + Sbjct: 61 IKTDVTDRESVKNLVDTAVKTYGRVDVLLNNAGVMPLSPLEKLRVDEWELMVDVNIKGVL 120 Query: 547 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 Y A+PH+ K G G + G Y+ +K +V + + + +R Sbjct: 121 YGIAAALPHMKSQKFGHIINVSSVAGHKVIDGGAVYSATKFAVRALSEGLRAEVKSYNLR 180 Query: 724 VTV 732 T+ Sbjct: 181 TTI 183 >UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=34; cellular organisms|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Silicibacter pomeroyi Length = 260 Score = 72.9 bits (171), Expect = 7e-12 Identities = 46/183 (25%), Positives = 79/183 (43%), Gaps = 4/183 (2%) Frame = +1 Query: 190 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLS 366 +TM GK + + GA L L R L +++ + + Sbjct: 9 MTMELKGKTIIITGASSGIGASAALLFASEGANLVLGARRAAELNQLTGQITQSNGRAVC 68 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSI 543 + D+T E+ +++ YG+LD NNAG++ E G + S A + ++ TN+ S Sbjct: 69 LAGDVTDEAYAHRLVDLARSEYGRLDGAFNNAGMMGEIGPVAEMSAANWTEVITTNLTSA 128 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIRS--FPGVLAYNISKASVDQFTRCVALXLAPKG 717 ++ +P L+E G G+ + PG+ AY SKA + R +A A +G Sbjct: 129 FFSAKAQIPALVEQGGVLVFTSSFVGVDNGGMPGMGAYAASKAGLVGLVRSLAADHAAEG 188 Query: 718 VRV 726 +RV Sbjct: 189 IRV 191 >UniRef50_Q3W2E5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 267 Score = 72.9 bits (171), Expect = 7e-12 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 1/147 (0%) Frame = +1 Query: 289 LSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVNNAG 465 L+ E L + + + A T+S+ AD++ + + + +GKLDVL N AG Sbjct: 50 LAAKALETEALATEALETARVAGTVSVRQADVSDPGACAEAVAACVAEFGKLDVLGNVAG 109 Query: 466 IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVL 645 I ++ QY R+M N+ + ++L A+PHLLE+ G G++ P Sbjct: 110 IYLAEHTTKVTVEQYRRVMGVNLDACFFLAQAAIPHLLETGGNIVNIASNAGLQGVPYSA 169 Query: 646 AYNISKASVDQFTRCVALXLAPKGVRV 726 AY++SK V TR +A+ +RV Sbjct: 170 AYSMSKGGVVALTRSLAVEFLKTPLRV 196 >UniRef50_Q2C7C6 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Photobacterium sp. SKA34|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Photobacterium sp. SKA34 Length = 197 Score = 72.9 bits (171), Expect = 7e-12 Identities = 34/110 (30%), Positives = 62/110 (56%) Frame = +1 Query: 397 IEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL 576 ++ I +T ++ K+D+L+NNAG+ GTI ++S+ ++++ + N+ Y + +PHL Sbjct: 1 MKNFIDQTTKNFNKVDILMNNAGVHIPGTILDSSVQYWEKISSVNINGAIYCSKYTLPHL 60 Query: 577 LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 +ESKG G+ + G Y +SK + TR +A+ +GVRV Sbjct: 61 IESKGCIVNNDSVSGLGADWGAAYYCVSKGVIVNLTRVLAMDFGLEGVRV 110 >UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase - gamma proteobacterium HTCC2207 Length = 253 Score = 72.9 bits (171), Expect = 7e-12 Identities = 43/156 (27%), Positives = 78/156 (50%), Gaps = 2/156 (1%) Frame = +1 Query: 265 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 F+S+ GA++ L N + Q + + + + D+ + +E +++ T+D +G +D Sbjct: 25 FVSE-GAKVMLADINTDITQPLVNELGAYRCAC-VAVDVAEADQVENMVRTTVDTFGSID 82 Query: 445 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX-X 618 V V NAG + G+I +T ++ D+++ NVR ++ +P + + G Sbjct: 83 VFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGVWLGLHYVMPVMRDGGGGSIIITSSGA 142 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G++ P AYN SK +V RC AL A G+RV Sbjct: 143 GVQGSPNTAAYNTSKHAVIGLMRCAALESAQFGIRV 178 >UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Marinomonas sp. MWYL1 Length = 244 Score = 72.9 bits (171), Expect = 7e-12 Identities = 43/181 (23%), Positives = 84/181 (46%), Gaps = 2/181 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 375 M VV + + GA+ L R + L ++K+ + L++ Sbjct: 1 MQIKNSVVLITGASSGIGEATARTVVQAGARAVLLARRQDRLDDLAKELGE--DVLALPC 58 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 555 D+T +++K ++ D YG++DVL+NNAG IE+ ++ + L+N N + + Sbjct: 59 DVTNPVEVQKAVQIAQDKYGRIDVLINNAGQGLYAAIEDITIEDFQELLNINTVAPLIMM 118 Query: 556 MLAVPHLLESKGXXXXXXXXXG--IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 +P L+ +G G + ++PG AY SK++++ ++ L LA G+ V+ Sbjct: 119 QAVIP-LMRKQGAGCIINVSSGATLATYPGSAAYTSSKSALNMISKVARLELADAGISVS 177 Query: 730 V 732 + Sbjct: 178 L 178 >UniRef50_A6CPA0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus sp. SG-1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. SG-1 Length = 240 Score = 72.9 bits (171), Expect = 7e-12 Identities = 44/155 (28%), Positives = 76/155 (49%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSK-DCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L K ++SL G + + + K + F SI AD++ E D+ K +++T+ +GK+D Sbjct: 24 LLKKSVKVSLVGSSAQIHETAEKLKNEGFDHLHSIQADVSIEQDVTKAVEETVKQFGKID 83 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 +LVNNAGI E + ++ +L NV +++ + +P++ E K G Sbjct: 84 ILVNNAGIGFFKPTEEVTSEEWRKLFEVNVHGVFHFSKAVLPYMKEQKFGSLITISSDVA 143 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + P AY SK +V F +A + G+RV Sbjct: 144 RYTIPNGAAYVASKYAVQGFCGSLAQEVREYGIRV 178 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 72.9 bits (171), Expect = 7e-12 Identities = 44/182 (24%), Positives = 86/182 (47%), Gaps = 1/182 (0%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITAD 378 N KVV LS+ GA+L L R ++ L+K+ + + ++ T D Sbjct: 3 NVKDKVVVITGASSGIGEETVNLLSENGAKLVLGARRLDRLEKIQQKVGHDSVSIKKT-D 61 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 +TK ++ +I+ + +G++DVL+NNAG++ +E +++++++ N++ + Y Sbjct: 62 VTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYGIG 121 Query: 559 LAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 +P++ + K G G FPG Y +K +V T + A G + + Sbjct: 122 AVLPYMRKQKSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGSNIRTT 181 Query: 736 IL 741 IL Sbjct: 182 IL 183 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 72.5 bits (170), Expect = 1e-11 Identities = 47/176 (26%), Positives = 80/176 (45%), Gaps = 3/176 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLT 384 GKVV L GA+++L N ++L K + + +IT ++T Sbjct: 3 GKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVT 62 Query: 385 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY-LTM 558 E D+E +K+T+D +GK+DV NNAG+ I A ++++M+ NV ++ L Sbjct: 63 VEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLKH 122 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + + G G+++Y SK +V T+ AL +A G+RV Sbjct: 123 VMKQMKKQGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRV 178 >UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae|Rep: Blr0893 protein - Bradyrhizobium japonicum Length = 279 Score = 72.5 bits (170), Expect = 1e-11 Identities = 45/152 (29%), Positives = 77/152 (50%), Gaps = 3/152 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ + GR + + ++K A+ + D+T E+ ++ +I +D +G++D L NN Sbjct: 30 GAKIVIAGRRLPEGEALAKQLG--ANCIFRQTDVTVEAQMQALIALAVDKFGRIDCLFNN 87 Query: 460 A-GIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXG-IRS 630 A G +TG IE + ++D M T VRS+ A P++ + G G + Sbjct: 88 AGGPAQTGGIEGLEVERFDAAMATLVRSVMLGMKHAAPYMKKQGSGSIINNGSIAGRLAG 147 Query: 631 FPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 F + Y +KA+V T+CVA+ L VRV Sbjct: 148 FSSSVVYGAAKAAVIHLTKCVAMELGESNVRV 179 >UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter bemidjiensis Bem|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter bemidjiensis Bem Length = 253 Score = 72.5 bits (170), Expect = 1e-11 Identities = 44/151 (29%), Positives = 77/151 (50%), Gaps = 2/151 (1%) Frame = +1 Query: 280 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 459 GA++ + + + L +KD + +I D++K DI++++ I+ G LDVLVNN Sbjct: 26 GAEVCVCDIDEKALDTAAKD---ISGLKTIVCDVSKPDDIKRMVTSAIEALGGLDVLVNN 82 Query: 460 AGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR-SF 633 AGI T +E+ Q++ +M +V +++T L +PHL +S G R + Sbjct: 83 AGIAGPTAPVEDVDPDQWEAVMTVDVIGTFHVTRLCIPHLKKSAAGSIVVMSSLGGRFGY 142 Query: 634 PGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 P AY +K + F + ++ L P +RV Sbjct: 143 PNRSAYCTAKMGLIGFAKTLSRELGPYNIRV 173 >UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR precursor - Delftia acidovorans SPH-1 Length = 264 Score = 72.5 bits (170), Expect = 1e-11 Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Frame = +1 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 549 AD++ ++ + K + G LD+LVNNAG+ TG +E LA + R ++ N+ + Sbjct: 61 ADVSDALQVQALFKAVDNELGGLDILVNNAGVAGPTGAVETLDLADWQRTLDVNITGAFL 120 Query: 550 LTMLAVPHLLES-----KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 T LAVP L +S + G PG AY+ SK +V FT+ +AL L Sbjct: 121 CTRLAVPRLRQSAREGRQAAIVNLSSAAGHLGMPGRSAYSASKWAVIGFTKSLALELGAD 180 Query: 715 GVRV 726 G+RV Sbjct: 181 GIRV 184 >UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR; n=13; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Arthrobacter sp. (strain FB24) Length = 297 Score = 72.5 bits (170), Expect = 1e-11 Identities = 41/118 (34%), Positives = 63/118 (53%), Gaps = 1/118 (0%) Frame = +1 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 552 DL + +++ + G LD+LVNNAG + IE S Q+D + TNV ++++L Sbjct: 111 DLKDAAVCRELVDTAVRELGGLDILVNNAGKQVAQEDIEEISDEQFDHTLKTNVYAMFWL 170 Query: 553 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 T AVPHL + P ++ Y +KAS++ FT+ +A LAPKG+RV Sbjct: 171 TKAAVPHL-PAGSTIINTTSIQAYNPSPTLVDYATTKASINNFTKGLAQQLAPKGIRV 227 >UniRef50_Q2R3W3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed; n=10; Oryza sativa|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 354 Score = 72.5 bits (170), Expect = 1e-11 Identities = 52/178 (29%), Positives = 83/178 (46%), Gaps = 3/178 (1%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADL 381 GKVV +K GA ++LT R L+ V+K + L + AD+ Sbjct: 52 GKVVLVTGASSGIGEHLVYEYAKKGACVALTARTEIALRAVAKTARDLGAPDVLVVPADI 111 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIYYLTM 558 TK D ++ +++T+ H+GKL+ LV NAGI + E T++ + +++ N Y T Sbjct: 112 TKVDDAKRAVEETVAHFGKLNHLVANAGIWSSCFFEEITNITAFHNVIDLNFWGAVYPTY 171 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 A+P+L S+G G + YN SK +V +F + L VRVT+ Sbjct: 172 FALPYLKASRGNIVVTSSVAGRVPTARMSFYNASKGAVIRFYETLRAELG-SHVRVTI 228 >UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13; n=4; Bilateria|Rep: Dehydrogenases, short chain protein 13 - Caenorhabditis elegans Length = 257 Score = 72.5 bits (170), Expect = 1e-11 Identities = 48/156 (30%), Positives = 82/156 (52%), Gaps = 3/156 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L GA + + R EN+ + V+ + TA + +SD K+I T+D + KLD Sbjct: 31 LGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSDRTKLIDFTLDRFTKLD 90 Query: 445 VLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 618 +LV+NA + G + + +Q+D+L++ NV+S + LT AVPHL S +G Sbjct: 91 ILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEAVPHLEASGRGNVVFVSSVA 150 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G + AY++ K ++ ++ +AL LA + +RV Sbjct: 151 GYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRV 186 >UniRef50_A6QZL8 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 1002 Score = 72.5 bits (170), Expect = 1e-11 Identities = 45/197 (22%), Positives = 91/197 (46%), Gaps = 2/197 (1%) Frame = +1 Query: 142 SQQEVFNTVSH*KYSEVTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL 321 S++ N ++H ++ +G+V L++ GA ++L R ++ L Sbjct: 742 SRKHCLNRIAHPPPKDL---LSGRVAVITGASSGIGAAVAAGLAREGAHVALGARRMKVL 798 Query: 322 QKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTS 498 + + ++ + D+T +S +E +++ D G +DVLV AG++ + NT Sbjct: 799 EAIKSSLPLRYNKAIIRQTDVTDKSQVEALVRAAHDELGPVDVLVVCAGVMYFTMMANTQ 858 Query: 499 LAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVD 675 + ++DR ++ N + + + VP +L +G G + FPG+ Y SK V+ Sbjct: 859 MEEWDRTVDVNCKGLLHCLGATVPSMLSRGRGQIVAISSDAGRKVFPGLSVYFASKFFVE 918 Query: 676 QFTRCVALXLAPKGVRV 726 + + L A KG+R+ Sbjct: 919 ATLQGLRLETAGKGLRI 935 >UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member 10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human) Length = 270 Score = 72.5 bits (170), Expect = 1e-11 Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 1/176 (0%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 381 +AGKVV GA++ + ++ + + ++ + I D+ Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQE---LPGAVFILCDV 63 Query: 382 TKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Y LT Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 Query: 559 LAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 LA+P+L +S+G G + Y +K +V T+ +AL +P GVRV Sbjct: 124 LALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179 >UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 247 Score = 72.1 bits (169), Expect = 1e-11 Identities = 42/183 (22%), Positives = 81/183 (44%), Gaps = 3/183 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 375 N+ GKV ++ GA + + + + Q+ + + L++ Sbjct: 8 NYTGKVAFVTGAANGIGRATALAFAREGANVVVADVSEQGNQETVRLIEDLGGRVLAVKC 67 Query: 376 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYL 552 D+T+ D+ + KTI+ +G+LD NNAG+ + A++DR++NT++RS++ Sbjct: 68 DVTRTEDVTAALSKTIETFGRLDFAFNNAGVEQKKAATAELEEAEWDRIVNTDLRSVFLC 127 Query: 553 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVT 729 +P +L + G G+ G AY +K V T+ AL A + +R+ Sbjct: 128 LKHEIPLMLKQGGGAIVNTSSGAGVIGIKGGAAYTAAKHGVIGLTKAAALDYASQNIRIN 187 Query: 730 VSI 738 + Sbjct: 188 XRV 190 >UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; Leptospira|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Leptospira interrogans Length = 256 Score = 72.1 bits (169), Expect = 1e-11 Identities = 51/190 (26%), Positives = 86/190 (45%), Gaps = 13/190 (6%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SIT 372 M+ GK V +K GA++ L+ + E L++ KD + + S Sbjct: 1 MDIKGKTVLVTGSASGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKTLGTEVYSFK 60 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII----------ETG-TIENTSLAQYDRL 519 AD++KE D EK+++ + +G LDV + NAGI+ ETG I SL+ + + Sbjct: 61 ADVSKEEDAEKLMQSAVKQFGSLDVAILNAGILRDGLLVKTDKETGKVISKMSLSNWQSV 120 Query: 520 MNTNVRSIYYLTMLAVPHLLESKGXXXXX-XXXXGIRSFPGVLAYNISKASVDQFTRCVA 696 ++ N+ ++ A ++ESK + PG Y+ +KA V T+ A Sbjct: 121 IDVNLTGVFLTGREAAIQMIESKSKGVIIPIASVAMHGNPGQTNYSAAKAGVASMTKLWA 180 Query: 697 LXLAPKGVRV 726 L+ G+RV Sbjct: 181 KELSRYGIRV 190 >UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=14; Clostridia|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium tetani Length = 249 Score = 72.1 bits (169), Expect = 1e-11 Identities = 35/121 (28%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 546 I D++ D + +I+K I +GK+D+L+NNAGI + G + +D ++NTN++ ++ Sbjct: 63 IKCDVSSYEDTKLMIEKIIRDFGKIDILINNAGISKIGLFIDMEEEDWDNIINTNLKGVF 122 Query: 547 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 + +P+++ E G G + Y+ SK VD FT+ +A + P +R Sbjct: 123 NCSRNVLPYMIGEKNGVIINISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIR 182 Query: 724 V 726 V Sbjct: 183 V 183 >UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 258 Score = 72.1 bits (169), Expect = 1e-11 Identities = 43/168 (25%), Positives = 82/168 (48%), Gaps = 1/168 (0%) Frame = +1 Query: 208 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 387 GKV L++ GA++ +T NV++ Q ++ + A + + D++ Sbjct: 6 GKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGA--IFLRHDVSD 63 Query: 388 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 567 E+ II++T+ +G+LD+LVNNAG++ +E+T++ + + ++ A+ Sbjct: 64 EAQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCKHAI 123 Query: 568 PHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLA 708 P + S G GI +P V AY+ SK ++ T+ VA+ A Sbjct: 124 PAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIRAMTKSVAVHCA 171 >UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB18) Length = 254 Score = 72.1 bits (169), Expect = 1e-11 Identities = 36/125 (28%), Positives = 57/125 (45%) Frame = +1 Query: 352 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 531 A +++ D++ D ++ + + +G++DVLVN AG+ E E T LA + +TN Sbjct: 64 AQGIAVAGDISNSEDARAMVGEVVARFGRIDVLVNCAGVAEYRAFEATDLAMFRATFDTN 123 Query: 532 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 711 V + A+PHL G R P Y SKA+V T +A P Sbjct: 124 VFGTVAMIQAALPHLTAPGGRIINFSSALATRPIPTASIYAASKAAVSALTHALAKEFGP 183 Query: 712 KGVRV 726 +G+ V Sbjct: 184 RGITV 188 >UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family - Psychroflexus torquis ATCC 700755 Length = 245 Score = 72.1 bits (169), Expect = 1e-11 Identities = 50/161 (31%), Positives = 84/161 (52%), Gaps = 8/161 (4%) Frame = +1 Query: 268 LSKLGAQLSLTGRN-----VENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHY 432 L + GA+L +T R +++L++ D F S D+T +S +KII T+D + Sbjct: 30 LGEAGAKLVVTSRTDKFGGLDSLKEAGHDVSFFES------DITDKSVPQKIIDYTLDKH 83 Query: 433 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL-TMLAVPHLLESKGXXXXXX 609 G +D+LVNNAG+ + G +E + D++MN NV S++ + + P + G Sbjct: 84 GVIDILVNNAGVAQHGEMEEFNDELLDKIMNINVDSVFRMCRSVLTPMKKQGSGVILNIG 143 Query: 610 XXXG-IRSFP-GVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G + + P +AYN SKA+V T+ +A A + +RV Sbjct: 144 SISGLVSNIPQPQVAYNASKAAVHMMTKSLASDFADQNIRV 184 >UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 275 Score = 72.1 bits (169), Expect = 1e-11 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 2/179 (1%) Frame = +1 Query: 202 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITAD 378 F GKV L++ GA +++T N E + V+ + + S+ D Sbjct: 4 FQGKVAFVTGGGSGLGRALSEELARRGAVIAVTDINAEAAEHVAAAITESGGKSCSMKLD 63 Query: 379 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 558 +++ D+ I + YG+LD + NNAGII G + + L + RL++ N+ + Y T Sbjct: 64 VSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYGTT 123 Query: 559 LAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 A H++ + G G+ P AY +K +V + + + GVR+TV Sbjct: 124 AAYSHMVRQGYGHIVNIASVGGLVPLPTYAAYAATKHAVVGLSTSMRPEASKLGVRITV 182 >UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Planctomycetaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Blastopirellula marina DSM 3645 Length = 256 Score = 72.1 bits (169), Expect = 1e-11 Identities = 40/155 (25%), Positives = 76/155 (49%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 444 ++ GA++++ RN E L + + + D+TK +E ++ ++ + KLD Sbjct: 35 MASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVTKRESVEAVVDAVMEKWEKLD 94 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 VLVNNAG+ + + ++D ++ TN+R ++ T A ++ ++ G G Sbjct: 95 VLVNNAGVTRDNLLPVMTDDEWDNVIETNLRGMFLFTRAASKQMMRARFGRIINISSVSG 154 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 + PG Y+ SKA + FTR ++ L + V V Sbjct: 155 LMGNPGQTNYSASKAGMIGFTRSLSRELGKRKVTV 189 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 72.1 bits (169), Expect = 1e-11 Identities = 43/159 (27%), Positives = 81/159 (50%), Gaps = 3/159 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L++ GA++ ++ + E +KV + + + I D+ KE + + +I+ T++ YGKL Sbjct: 26 LAREGAKIVVSDIDEEGGKKVVQQIKEDGGEAIFIKQDVAKEDEWKNVIETTLETYGKLH 85 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL--LESKGXXXXXXXXX 618 +L N+AGI GT+E+ +L + L++ N+ + T + + + G Sbjct: 86 ILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGTKYGIKGMRKTDEGGSIINFSSIE 145 Query: 619 GIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTVS 735 G+ P + AYN SK V FT+ AL A +G + ++ Sbjct: 146 GLIGDPNLPAYNASKGGVTIFTKSAALHCAKQGYGIRIN 184 >UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rhodobacteraceae|Rep: Short-chain dehydrogenase/reductase SDR - Sagittula stellata E-37 Length = 275 Score = 72.1 bits (169), Expect = 1e-11 Identities = 37/133 (27%), Positives = 75/133 (56%), Gaps = 3/133 (2%) Frame = +1 Query: 349 FASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNT 528 FA+ ++ D+ ++ +E++++ D +G++D+L N G+ ++G T+ A + R+ + Sbjct: 65 FAAEAAVV-DVLDDASVERLVEGVADRHGRIDILHCNVGLGKSGPSGQTTPADWRRISDA 123 Query: 529 NVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRS--FPGVLAYNISKASVDQFTRCVAL 699 N+ S++ +PH+ + +G IR+ +P LAY+ +KA +QF R +A+ Sbjct: 124 NLTSLHVAAQAVLPHMRAQGRGVITVTSSIASIRNVGYPH-LAYSATKAGANQFARALAV 182 Query: 700 XLAPKGVRVTVSI 738 LAP+ +RV I Sbjct: 183 ELAPENIRVNAII 195 >UniRef50_A0Z805 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; marine gamma proteobacterium HTCC2080|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - marine gamma proteobacterium HTCC2080 Length = 257 Score = 72.1 bits (169), Expect = 1e-11 Identities = 44/183 (24%), Positives = 87/183 (47%), Gaps = 6/183 (3%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDC-DKFASTLSI 369 M+ G+ L++LG + + ++ Q V K+ D A +++ Sbjct: 1 MSHLGQTALITGASSGVGAATALKLAQLGINVVVNYNSSLSGAQAVVKNITDLGAQAIAV 60 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAG---IIETGTIENTSLAQYDRLMNTNVRS 540 D+++E D +I++KTI+ +G+LD+L+NNAG + +E + + + + N+ Sbjct: 61 QGDVSQEKDCRRIVEKTIERFGRLDILINNAGTTTFVPHHDLEGLTEDIWHQTLGVNLMG 120 Query: 541 IYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKG 717 +++ AVP+L E+ G + + +AY SKA ++ T+ +A L G Sbjct: 121 AFFMCREAVPYLREAGSGVVVMTSSIASVTANGSSIAYCASKAGMNSLTKTLAKTLGSDG 180 Query: 718 VRV 726 +RV Sbjct: 181 IRV 183 >UniRef50_A7RZW0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 300 Score = 72.1 bits (169), Expect = 1e-11 Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 8/163 (4%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS------TLSITADLTKESDIEKIIKKTIDH 429 L+K G +L L+ R L++V + C S L + D+T+ ++++ +DH Sbjct: 62 LAKFGCKLVLSARRRSELERVKEQCIANTSYNADQDILVLPMDVTEYDKHTELVRSVLDH 121 Query: 430 YGKLDVLVNNAGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXX 603 + K+D+L+NN+G + G +E + +++ N ++ LT +PH++E K G Sbjct: 122 FNKIDILINNSGRSQRGLAVETPGIEVEKAMLDLNFLAVVSLTKAVLPHMIERKNGHIVV 181 Query: 604 XXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRVTV 732 G P +YN +K +V + + + L PK + VT+ Sbjct: 182 TSSVAGKIGAPMSTSYNATKFAVQGYFDGLRVELFPKNIHVTL 224 >UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 249 Score = 72.1 bits (169), Expect = 1e-11 Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 3/127 (2%) Frame = +1 Query: 355 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 531 S L + D+T E D E++++ T+ +G++DV VNNAG + ++D++ N N Sbjct: 63 SMLFVKMDVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVN 122 Query: 532 VRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGI-RSFPGVLAYNISKASVDQFTRCVALXL 705 V+SI+Y T +P+++ + +G G R G++ YN SKA+V T+ +A Sbjct: 123 VKSIFYATRHFIPNVINQGEGGSMINIASIGASRPRAGLVWYNASKAAVVNATKGLAAEY 182 Query: 706 APKGVRV 726 PK +R+ Sbjct: 183 GPKNIRI 189 >UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein) reductase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: 3-oxoacyl-(acyl-carrier protein) reductase - Entamoeba histolytica HM-1:IMSS Length = 265 Score = 71.7 bits (168), Expect = 2e-11 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 2/174 (1%) Frame = +1 Query: 196 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDK--FASTLSI 369 MNF GKV L++ + GR E + +S + + F I Sbjct: 1 MNFEGKVALITGGTSGIGEAIVRQLTEQKCNVIFIGRRKELGESISHELNNKHFGQIDFI 60 Query: 370 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 549 D+T + + ++ + Y +LD+LVNNAGI+ T + + +D + TNV+S++ Sbjct: 61 PFDVTNFKEYDSLVHIVQEKYNRLDLLVNNAGIVTYDTCDELTEETFDLIYQTNVKSVWQ 120 Query: 550 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 711 +T L +S G I++ P Y+ SKA+V T+ +AL AP Sbjct: 121 MTKHFHNLLEQSYGAVVNIGSDVSIKADPQYFGYSDSKAAVMHITKMMALQYAP 174 >UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=4; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Rhodopirellula baltica Length = 273 Score = 71.7 bits (168), Expect = 2e-11 Identities = 49/159 (30%), Positives = 78/159 (49%), Gaps = 6/159 (3%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-----TLSITADLTKESDIEKIIKKTIDHY 432 L+ GA + L RN Q+ S +K A ++ I AD+T E+D+ +++ +D Sbjct: 48 LASAGANVCLVSRNE---QEASAAAEKIAGEYPVRSIGIGADVTVEADVANMVQACVDQL 104 Query: 433 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXX 609 LDVL+N+AGI G+I+ SL Q+ ++ +TNV ++ A + ++ G Sbjct: 105 SGLDVLINSAGINVRGSIDELSLEQFRQVQSTNVDGMWLCCKHASSVMKKNGSGRIINLA 164 Query: 610 XXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 G+ Y SK +V Q TR + L LAP V V Sbjct: 165 STLGLVGLANRTPYASSKGAVVQMTRALGLELAPHNVTV 203 >UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 272 Score = 71.7 bits (168), Expect = 2e-11 Identities = 42/157 (26%), Positives = 84/157 (53%), Gaps = 4/157 (2%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 444 L++ GA++++ NV+ +V+ D ++I AD++K++D E + ++T++ +G +D Sbjct: 27 LAREGARIAVVDLNVDAATRVASSIDPDGKRAIAIRADISKKADTEAMARQTLEAFGTID 86 Query: 445 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 618 +LVNNAG+ + + + +DR+M N + I + +P + + KG Sbjct: 87 ILVNNAGVGGASALACDVTEENWDRVMGVNAKGILFCCQAVIPAMKAQGKGKIVNIDSIA 146 Query: 619 GIR-SFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 GIR ++ + Y SK +V T+ +A LA + + V Sbjct: 147 GIRMAYFSSVDYTASKHAVTGLTQHLAWELADQRINV 183 >UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya majuscula Length = 246 Score = 71.7 bits (168), Expect = 2e-11 Identities = 38/121 (31%), Positives = 67/121 (55%) Frame = +1 Query: 364 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 543 ++ DL + +DIE++ + T + +LD+LVN+A ++TG+IE+ S+ + R+ N + Sbjct: 60 AMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRVFAVN-STA 118 Query: 544 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +LT+ L + G + + PG+ AY SK S++Q TR A LA +G+ Sbjct: 119 PFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRVAAWELADRGIT 178 Query: 724 V 726 V Sbjct: 179 V 179 >UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to 3-oxoacyl-[acyl carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 254 Score = 71.7 bits (168), Expect = 2e-11 Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 2/155 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 LS+ GA +++ R ++++ +++ + +L I AD+TK D+ K+++ + + +D Sbjct: 30 LSESGAHVAVASRTFSDVEETAQEIEGNGVKSLPIAADVTKPEDVTKMVEMVLSKFKTID 89 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 621 +LV+N G G+I++ SL + +++ N+ S Y H+L+ K G G Sbjct: 90 ILVSNVGAFIGGSIQDISLDDWHKMIEINLTSTYLCVKTVGKHMLDKKCGKIITMSSALG 149 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 I AY K V Q T+ +A+ A + V Sbjct: 150 IFGANRSSAYCSGKGGVIQLTKALAIEWAKYNINV 184 >UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogenase; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Short-chain alcohol-related dehydrogenase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 272 Score = 71.7 bits (168), Expect = 2e-11 Identities = 43/123 (34%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Frame = +1 Query: 367 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 546 I D+ ++ I +K ID GKLDVLVNNAGI G+IE+++ + + TNV I Sbjct: 48 IALDVLDDTTITPALKTIIDAEGKLDVLVNNAGIGMLGSIEDSTAEEVKEVFETNVYGIL 107 Query: 547 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPKGVR 723 +PH+ E K G G P Y+ +KASV T + + L P GV Sbjct: 108 RTCQAVLPHMRERKMGLIINVSSIAGYMGLPYRGIYSATKASVHMITEAMRMELKPYGVH 167 Query: 724 VTV 732 V Sbjct: 168 ACV 170 >UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 266 Score = 71.7 bits (168), Expect = 2e-11 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 2/153 (1%) Frame = +1 Query: 268 LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 444 L+ GA L L R+ L +V+ + K +T DL + +E + +D +D Sbjct: 29 LADAGASLILAARDAAKLGEVADEVRAKGRDARIVTFDLADMASVEAAARGLVDEGAPID 88 Query: 445 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM-LAVPHLLESKGXXXXXXXXXG 621 +LVNN GI E G + +SL ++R + NV +IY L L+ P G Sbjct: 89 ILVNNGGIAEWGPLHGSSLDHWERTFDVNVSAIYLLCRELSKPMAERGWGRIINFASYVA 148 Query: 622 IRSFPGVLAYNISKASVDQFTRCVALXLAPKGV 720 P + AY SK +V TR VA LAP GV Sbjct: 149 ETGRPNLSAYVASKHAVLGLTRAVAADLAPHGV 181 >UniRef50_Q9URX0 Cluster: Short chain dehydrogenase; n=1; Schizosaccharomyces pombe|Rep: Short chain dehydrogenase - Schizosaccharomyces pombe (Fission yeast) Length = 258 Score = 71.7 bits (168), Expect = 2e-11 Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Frame = +1 Query: 355 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 534 + L++ AD++K IE I+K I G +DVL+NNAG+ + E S +D ++ + Sbjct: 46 AALALQADVSKADQIETAIEKVIQTLGPIDVLINNAGLADDTPFEQLSHESWDHDVSLVL 105 Query: 535 RSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 711 R Y +PH+ + KG + G AY+ +KA ++ T+ +A+ P Sbjct: 106 RGNYLTQRYVIPHMAKQGKGGSIVNIGSVNGHIYLGSPAYSAAKAGLENLTKALAVRYGP 165 Query: 712 KGVRVTV 732 G+RV V Sbjct: 166 LGIRVNV 172 >UniRef50_Q7RV91 Cluster: TETRAHYDROXYNAPHTHALENE REDUCTASE; n=121; Pezizomycotina|Rep: TETRAHYDROXYNAPHTHALENE REDUCTASE - Neurospora crassa Length = 282 Score = 71.7 bits (168), Expect = 2e-11 Identities = 44/179 (24%), Positives = 87/179 (48%), Gaps = 3/179 (1%) Frame = +1 Query: 199 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFAS-TLSIT 372 + GKV L + GA++ + N + + +V + K S ++I Sbjct: 26 HLGGKVALVTGAGRGIGREMALELGRRGAKVVVNYANSDISANEVVQAIKKIGSDAVAIK 85 Query: 373 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 552 A+++ S IE++ ++ +GKLD++ +N+G++ G I++ + +YDR+ N N R +++ Sbjct: 86 ANVSDVSQIERLFREAKQRFGKLDIVCSNSGVVSFGHIKDVTPEEYDRVFNINTRGQFFV 145 Query: 553 TMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALXLAPKGVRV 726 A + LE G G ++ P Y+ SK +++ F RC+A+ K + V Sbjct: 146 AREAYKN-LEVGGRLILMGSITGQAKAVPKHTVYSASKGAIETFVRCMAIDFGDKKITV 203 >UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolobus acidocaldarius|Rep: Short chain dehydrogenase - Sulfolobus acidocaldarius Length = 255 Score = 71.7 bits (168), Expect = 2e-11 Identities = 38/129 (29%), Positives = 71/129 (55%), Gaps = 2/129 (1%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVR 537 L + AD++K+ D+E+ +++T + Y ++DVL NNAGI++ T + S ++R++ N+ Sbjct: 60 LGVKADVSKKKDVEEFVRRTFETYSRIDVLCNNAGIMDGVTPVAEVSDELWERVLAVNLY 119 Query: 538 SIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK 714 S +Y + +P +L + KG GIR Y ++K + TR +A + Sbjct: 120 SAFYSSRAVIPIMLKQGKGVIVNTASIAGIRGGFAGAPYTVAKHGLIGLTRSIAAHYGDQ 179 Query: 715 GVRVTVSIL 741 G+R V++L Sbjct: 180 GIR-AVAVL 187 >UniRef50_UPI000023D9EA Cluster: hypothetical protein FG11198.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG11198.1 - Gibberella zeae PH-1 Length = 291 Score = 71.3 bits (167), Expect = 2e-11 Identities = 40/124 (32%), Positives = 64/124 (51%), Gaps = 2/124 (1%) Frame = +1 Query: 361 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 540 L+I AD++ DIEK+I+ T+D +GK+D ++ NA +E+T+ +D+ NV+ Sbjct: 56 LAIKADVSSIPDIEKLIQATVDKFGKIDCVMANAACAPMNDLESTTEEAFDKSFMLNVKG 115 Query: 541 IYYLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAPK- 714 Y+L AVPH+ + + P L Y SK ++Q TR +A L K Sbjct: 116 PYFLVQKAVPHMPRDGRVILVSTGILHNSNVVPRYLLYAASKGPIEQMTRVMAKELGAKH 175 Query: 715 GVRV 726 G+ V Sbjct: 176 GITV 179 >UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomonadaceae|Rep: Pteridine reductase 1 - Xylella fastidiosa Length = 245 Score = 71.3 bits (167), Expect = 2e-11 Identities = 40/125 (32%), Positives = 66/125 (52%) Frame = +1 Query: 352 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 531 +STL++ DL + + E +I + H+G+LDVL+NNA + + AQ+D L N Sbjct: 56 SSTLALLGDLHENAVPEMLIARCAGHFGRLDVLINNASNFYPTPLGEVTPAQWDDLFAIN 115 Query: 532 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALXLAP 711 ++ ++L A P L + +G G + Y +KA+++ TR +AL LAP Sbjct: 116 AKAPFFLAQAATPLLRKHRGAIINLTDLHGTQPLRRHAVYTAAKAALEMLTRSLALELAP 175 Query: 712 KGVRV 726 + VRV Sbjct: 176 Q-VRV 179 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 685,186,133 Number of Sequences: 1657284 Number of extensions: 13239179 Number of successful extensions: 36298 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 33989 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 35003 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 60500186565 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -