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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P01_F_C14
         (695 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A5A7A0 Cluster: Mevalonate kinase; n=1; Bombyx mori|Rep...   204   2e-51
UniRef50_UPI00015B4200 Cluster: PREDICTED: similar to mevalonate...    71   4e-11
UniRef50_UPI0000587FA1 Cluster: PREDICTED: similar to Mevalonate...    66   1e-09
UniRef50_A7SJK4 Cluster: Predicted protein; n=1; Nematostella ve...    63   5e-09
UniRef50_UPI0000E810F5 Cluster: PREDICTED: hypothetical protein;...    57   5e-07
UniRef50_UPI0000D56452 Cluster: PREDICTED: similar to mevalonate...    56   6e-07
UniRef50_UPI000155619E Cluster: PREDICTED: hypothetical protein,...    55   1e-06
UniRef50_A3LQ81 Cluster: Mevalonate kinase; n=5; Saccharomycetal...    55   1e-06
UniRef50_Q65XX9 Cluster: Putative uncharacterized protein; n=5; ...    55   2e-06
UniRef50_Q03426 Cluster: Mevalonate kinase; n=26; Euteleostomi|R...    54   3e-06
UniRef50_Q6CEF6 Cluster: Yarrowia lipolytica chromosome B of str...    54   4e-06
UniRef50_UPI0000DB6B27 Cluster: PREDICTED: similar to Mevalonate...    52   1e-05
UniRef50_Q7PWI8 Cluster: ENSANGP00000021364; n=2; Culicidae|Rep:...    52   2e-05
UniRef50_Q0UWF5 Cluster: Putative uncharacterized protein; n=1; ...    52   2e-05
UniRef50_Q4WP25 Cluster: Mevalonate kinase; n=15; Pezizomycotina...    50   5e-05
UniRef50_Q86AG7 Cluster: Similar to Rattus norvegicus (Rat). Mev...    49   1e-04
UniRef50_Q4TG59 Cluster: Chromosome undetermined SCAF3891, whole...    49   1e-04
UniRef50_A2SR97 Cluster: Mevalonate kinase; n=4; Methanomicrobia...    48   3e-04
UniRef50_Q09780 Cluster: Putative mevalonate kinase; n=1; Schizo...    47   4e-04
UniRef50_Q8TT37 Cluster: Mevalonate kinase; n=5; Euryarchaeota|R...    46   7e-04
UniRef50_P07277 Cluster: Mevalonate kinase; n=3; Saccharomycetal...    46   9e-04
UniRef50_Q50559 Cluster: Mevalonate kinase; n=2; Methanothermoba...    46   9e-04
UniRef50_Q0LHN3 Cluster: Mevalonate kinase; n=2; Chloroflexi (cl...    46   0.001
UniRef50_A0B6E3 Cluster: Mevalonate kinase; n=1; Methanosaeta th...    46   0.001
UniRef50_Q9V187 Cluster: Mevalonate kinase; n=4; Thermococcaceae...    46   0.001
UniRef50_Q58487 Cluster: Mevalonate kinase; n=1; Methanocaldococ...    44   0.003
UniRef50_Q7K2V9 Cluster: GH04687p; n=1; Drosophila melanogaster|...    44   0.004
UniRef50_Q756D2 Cluster: AER335Wp; n=3; Saccharomycetaceae|Rep: ...    44   0.004
UniRef50_O27995 Cluster: Mevalonate kinase; n=1; Archaeoglobus f...    44   0.004
UniRef50_Q9HQI6 Cluster: Mevalonate kinase; n=5; Halobacteriacea...    43   0.006
UniRef50_Q2HTL9 Cluster: Mevalonate and galactokinase; n=5; core...    43   0.008
UniRef50_A1RYL2 Cluster: Mevalonate kinase; n=1; Thermofilum pen...    43   0.008
UniRef50_P46086 Cluster: Mevalonate kinase; n=8; Magnoliophyta|R...    43   0.008
UniRef50_UPI000155611C Cluster: PREDICTED: hypothetical protein,...    42   0.014
UniRef50_A5UV63 Cluster: Mevalonate kinase; n=3; Chloroflexaceae...    42   0.014
UniRef50_A2E1U7 Cluster: Mevalonate kinase family protein; n=1; ...    41   0.033
UniRef50_A7DRD8 Cluster: Mevalonate kinase; n=1; Candidatus Nitr...    41   0.033
UniRef50_UPI00015BB033 Cluster: mevalonate kinase; n=1; Ignicocc...    40   0.058
UniRef50_Q2NG06 Cluster: Putative mevalonate kinase; n=1; Methan...    40   0.058
UniRef50_A5UN66 Cluster: Mevalonate kinase; n=1; Methanobrevibac...    40   0.058
UniRef50_A3H636 Cluster: Mevalonate kinase; n=1; Caldivirga maqu...    40   0.058
UniRef50_Q74JA4 Cluster: Mevalonate kinase; n=7; Lactobacillus|R...    40   0.077
UniRef50_Q2BIK0 Cluster: Mevalonate kinase, putative; n=1; Neptu...    40   0.077
UniRef50_Q8TWN9 Cluster: Mevalonate kinase; n=1; Methanopyrus ka...    39   0.10 
UniRef50_A2BL67 Cluster: Mevalonate kinase; n=1; Hyperthermus bu...    39   0.13 
UniRef50_Q9Y946 Cluster: Mevalonate kinase; n=1; Aeropyrum perni...    39   0.13 
UniRef50_Q8L1I1 Cluster: Phosphomevalonate kinase; n=1; Paracocc...    38   0.18 
UniRef50_A6G140 Cluster: Hydroxymethylglutaryl-CoA reductase; n=...    38   0.18 
UniRef50_Q8L1I2 Cluster: Mevalonate kinase; n=1; Paracoccus zeax...    38   0.31 
UniRef50_A5EVP5 Cluster: GHMP kinase family protein; n=1; Dichel...    38   0.31 
UniRef50_A5EUV5 Cluster: GHMP kinase family protein; n=1; Dichel...    38   0.31 
UniRef50_Q6LXL5 Cluster: Mevalonate kinase; n=5; Methanococcus|R...    38   0.31 
UniRef50_A0E671 Cluster: Chromosome undetermined scaffold_8, who...    37   0.41 
UniRef50_Q7QVN5 Cluster: GLP_305_18405_19430; n=1; Giardia lambl...    36   0.72 
UniRef50_Q22LZ8 Cluster: ATPase, AAA family protein; n=1; Tetrah...    36   0.72 
UniRef50_Q83DT4 Cluster: Phosphomevalonate kinase, putative; n=2...    36   0.95 
UniRef50_Q03FN7 Cluster: Mevalonate kinase; n=1; Pediococcus pen...    36   0.95 
UniRef50_A6G138 Cluster: Mevalonate kinase; n=1; Plesiocystis pa...    36   0.95 
UniRef50_A2U564 Cluster: Mevalonate kinase; n=1; Bacillus coagul...    36   1.3  
UniRef50_Q9FD69 Cluster: Mevalonate kinase; n=4; Enterococcus|Re...    35   2.2  
UniRef50_Q2BIJ9 Cluster: GHMP kinase; n=1; Neptuniibacter caesar...    35   2.2  
UniRef50_Q2GZQ7 Cluster: Putative uncharacterized protein; n=1; ...    35   2.2  
UniRef50_Q97UL6 Cluster: (Phospho) mevalonate kinase, putative; ...    35   2.2  
UniRef50_A3DL21 Cluster: Mevalonate kinase; n=1; Staphylothermus...    34   2.9  
UniRef50_Q38X71 Cluster: Mevalonate kinase; n=1; Lactobacillus s...    34   3.8  
UniRef50_A5VK03 Cluster: Mevalonate kinase; n=2; Lactobacillus r...    34   3.8  
UniRef50_A4VT18 Cluster: Mevalonate kinase; n=4; Streptococcus|R...    34   3.8  
UniRef50_Q8F618 Cluster: Putative uncharacterized protein; n=2; ...    33   5.1  
UniRef50_Q83DT3 Cluster: Mevalonate kinase, putative; n=3; Coxie...    33   5.1  
UniRef50_Q8H912 Cluster: Putative zinc knuckle domain containing...    33   5.1  
UniRef50_Q7XJS3 Cluster: At2g17440 protein; n=3; Brassicaceae|Re...    33   5.1  
UniRef50_Q60ED2 Cluster: Putative uncharacterized protein OSJNBa...    33   5.1  
UniRef50_Q8SQK4 Cluster: MEVALONATE KINASE; n=1; Encephalitozoon...    33   5.1  
UniRef50_Q08UJ8 Cluster: Mevalonate kinase; n=2; Cystobacterinea...    33   6.7  
UniRef50_Q031R4 Cluster: Mevalonate kinase; n=3; Lactococcus lac...    33   6.7  
UniRef50_Q6C026 Cluster: Similarity; n=1; Yarrowia lipolytica|Re...    33   6.7  
UniRef50_Q8ZTT2 Cluster: Mevalonate kinase; n=4; Pyrobaculum|Rep...    33   6.7  
UniRef50_Q1WU40 Cluster: Mevalonate kinase; n=1; Lactobacillus s...    33   8.8  
UniRef50_A3HYY0 Cluster: Galactokinase; n=1; Algoriphagus sp. PR...    33   8.8  
UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|R...    33   8.8  
UniRef50_Q8TQ19 Cluster: Putative uncharacterized protein; n=2; ...    33   8.8  

>UniRef50_A5A7A0 Cluster: Mevalonate kinase; n=1; Bombyx mori|Rep:
           Mevalonate kinase - Bombyx mori (Silk moth)
          Length = 413

 Score =  204 bits (498), Expect = 2e-51
 Identities = 95/96 (98%), Positives = 95/96 (98%)
 Frame = +3

Query: 408 GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY 587
           GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY
Sbjct: 87  GITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTY 146

Query: 588 LPVKSMDISMGSELTIGAGTGSSASFAVCLXGALIQ 695
           LPVKSMDISMGSELTIGAGTGSSASFAVCL GALIQ
Sbjct: 147 LPVKSMDISMGSELTIGAGTGSSASFAVCLAGALIQ 182



 Score =  183 bits (445), Expect = 4e-45
 Identities = 87/87 (100%), Positives = 87/87 (100%)
 Frame = +2

Query: 149 MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH 328
           MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH
Sbjct: 1   MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIH 60

Query: 329 LPCVDLQETIPLEPTVKSLFHPKLAPG 409
           LPCVDLQETIPLEPTVKSLFHPKLAPG
Sbjct: 61  LPCVDLQETIPLEPTVKSLFHPKLAPG 87


>UniRef50_UPI00015B4200 Cluster: PREDICTED: similar to mevalonate
           kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to mevalonate kinase - Nasonia vitripennis
          Length = 388

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 38/70 (54%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQETIP 361
           +SAPGKVIL GEHSVVYGKTA+A SLGLRSS+   E+  PHE   +HI +P + + + + 
Sbjct: 6   ISAPGKVILFGEHSVVYGKTAVAASLGLRSSLHFTEL--PHEECIIHIKMPKLGISKILS 63

Query: 362 LEPTVKSLFH 391
           L   V+  FH
Sbjct: 64  LH-QVEEDFH 72



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/82 (32%), Positives = 47/82 (57%)
 Frame = +3

Query: 447 IDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSE 626
           ++HD   +++++Y+  +   F++   +Q+ S+  F Y    +  S  L + S  + + SE
Sbjct: 82  MNHDAINQKLQKYVATL--GFEN--PDQRLSMECFFYAMMQVIRSDQLRLSSFILELDSE 137

Query: 627 LTIGAGTGSSASFAVCLXGALI 692
           L+IGAG GSSASF VCL    +
Sbjct: 138 LSIGAGAGSSASFTVCLVACFL 159


>UniRef50_UPI0000587FA1 Cluster: PREDICTED: similar to Mevalonate
           kinase (MK); n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Mevalonate kinase (MK) -
           Strongylocentrotus purpuratus
          Length = 413

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 29/60 (48%), Positives = 46/60 (76%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 355
           ++ +SAPGK+ILHGEH+VV+GKTA+A  L LRS + +KE ++     +H++LP +DL+ +
Sbjct: 15  SIFISAPGKIILHGEHAVVHGKTALAAGLNLRSYLCLKEKDSGR---LHLNLPDIDLERS 71



 Score = 37.5 bits (83), Expect = 0.31
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
 Frame = +3

Query: 507 FDSLPNNQKNSLRSFLYVFSGIFGST-YLPVKSMDISMGSELTIGAGTGSSASFAVCLXG 683
           +      ++ ++ +FLY++  I G     P+  +D  + S L  GAG GSSA+F+VCL  
Sbjct: 108 YSDTETTKRLAVMAFLYLYLCIAGRNGKFPI--LDTLVSSALPPGAGLGSSAAFSVCLAA 165

Query: 684 ALI 692
            L+
Sbjct: 166 GLL 168


>UniRef50_A7SJK4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 415

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 28/40 (70%), Positives = 36/40 (90%)
 Frame = +2

Query: 170 LFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 289
           L  V VSAPGK+ILHGEH+VVYGK AIAVS+GLR+++V++
Sbjct: 3   LSRVVVSAPGKIILHGEHAVVYGKAAIAVSIGLRTTVVLQ 42


>UniRef50_UPI0000E810F5 Cluster: PREDICTED: hypothetical protein;
           n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 527

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 29/55 (52%), Positives = 40/55 (72%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQ 349
           VSAPGKVILHGEH+VV+GK A+AV+LGLR+ + ++         + IHLP V ++
Sbjct: 181 VSAPGKVILHGEHAVVHGKAALAVALGLRTFLRLRPGGGER---LRIHLPGVGVR 232



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 25/52 (48%), Positives = 36/52 (69%)
 Frame = +3

Query: 537 SLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGALI 692
           ++ +FLY+   I  + Y  V S+DI++ SEL  GAG GSSA++AVCL  AL+
Sbjct: 312 AILAFLYMCLAI-SAKYGDVPSVDIAVWSELPTGAGLGSSAAYAVCLAAALL 362


>UniRef50_UPI0000D56452 Cluster: PREDICTED: similar to mevalonate
           kinase; n=3; Endopterygota|Rep: PREDICTED: similar to
           mevalonate kinase - Tribolium castaneum
          Length = 490

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 26/37 (70%), Positives = 30/37 (81%)
 Frame = +2

Query: 170 LFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 280
           L  + VSAPGKVILHGEHSVVY K A+A SLGLR+ +
Sbjct: 95  LSEIRVSAPGKVILHGEHSVVYDKLAVAASLGLRTRL 131



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
 Frame = +3

Query: 414 TGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLP 593
           T  ++   P  +DHD     VE+++ L +         Q+ +L SF Y+F  I GST   
Sbjct: 172 TAYYNLTHPELLDHDKITEIVEKFVDLNRHE-----PKQRQALVSFFYLFFAIVGSTDSN 226

Query: 594 VKS-MDISMGSELTIGAGTGSSASFAVCLXGALI 692
           +     +++ S+LT+GAGTGSSASFAV +   L+
Sbjct: 227 LSDGFKLAVRSDLTVGAGTGSSASFAVAIAAFLL 260


>UniRef50_UPI000155619E Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein, partial - Ornithorhynchus anatinus
          Length = 282

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/60 (48%), Positives = 40/60 (66%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 355
           T+ VSAPGK ILHGEHSVV+GK A+AV+L LR+ +   +     +  V + LP + L+ T
Sbjct: 5   TLVVSAPGKAILHGEHSVVHGKVALAVALNLRTFL---QFRPGDQDRVTVSLPNLGLRRT 61



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 25/83 (30%), Positives = 43/83 (51%)
 Frame = +3

Query: 438 PHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISM 617
           P  +     + +++E+  L     DS    Q  +L +FLY+++ I G T      +D+++
Sbjct: 144 PSAVPTPERMEKLKEFAGLAPGPLDS----QGLALLAFLYLYTAI-GGTDGAWPGVDVTV 198

Query: 618 GSELTIGAGTGSSASFAVCLXGA 686
            SEL  G G GSSA+++ C   A
Sbjct: 199 WSELPPGGGLGSSAAYSACSASA 221


>UniRef50_A3LQ81 Cluster: Mevalonate kinase; n=5;
           Saccharomycetales|Rep: Mevalonate kinase - Pichia
           stipitis (Yeast)
          Length = 432

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDL-----Q 349
           VSAPGKVI+ GEHS VYGK AIA +L LR+ +++     P    +++  P ++L     +
Sbjct: 7   VSAPGKVIIFGEHSAVYGKPAIAAALSLRAYLLVTPSQDP--DTINLSFPDINLTHSWNK 64

Query: 350 ETIPLEPTVKSLFHPKLAPGXNRQILLEITPQ 445
             IP +  VK +      P  + +++ EI  Q
Sbjct: 65  NDIPWDSIVKHINLVDNLPQTSEELVPEIVDQ 96



 Score = 36.7 bits (81), Expect = 0.54
 Identities = 21/47 (44%), Positives = 27/47 (57%)
 Frame = +3

Query: 549 FLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGAL 689
           FLY+++ +       +  M   + S L IGAG GSSAS AVCL  AL
Sbjct: 116 FLYLYTHLCNQE---LAGMSFCIRSTLPIGAGLGSSASTAVCLASAL 159


>UniRef50_Q65XX9 Cluster: Putative uncharacterized protein; n=5;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 614

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/66 (42%), Positives = 46/66 (69%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 364
           VSAPGK+IL GEH+VVYG+TAIA S+ LR+ +    + T  +  +++ LP + +++T  L
Sbjct: 144 VSAPGKIILFGEHAVVYGRTAIAGSIDLRTYV---SLYTSADGRIYLSLPDLGVEKTWML 200

Query: 365 EPTVKS 382
           +  +K+
Sbjct: 201 KDLLKA 206


>UniRef50_Q03426 Cluster: Mevalonate kinase; n=26; Euteleostomi|Rep:
           Mevalonate kinase - Homo sapiens (Human)
          Length = 396

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 29/56 (51%), Positives = 40/56 (71%), Gaps = 1/56 (1%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPA-VHIHLPCVDLQ 349
           VSAPGKVILHGEH+VV+GK A+AVSL LR+ + ++    PH    V + LP + ++
Sbjct: 8   VSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQ----PHSNGKVDLSLPNIGIK 59



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 23/61 (37%), Positives = 37/61 (60%)
 Frame = +3

Query: 510 DSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGAL 689
           D     ++ ++ +FLY++  I       + S+DI + SEL  GAG GSSA+++VCL  AL
Sbjct: 99  DDCAVTERLAVLAFLYLYLSICRKQRA-LPSLDIVVWSELPPGAGLGSSAAYSVCLAAAL 157

Query: 690 I 692
           +
Sbjct: 158 L 158


>UniRef50_Q6CEF6 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 449

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/61 (40%), Positives = 39/61 (63%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 364
           +SAPGKVIL GEH+ V+GK AIA ++ LR+ +++ E  T   P V +  P + L   + +
Sbjct: 5   ISAPGKVILFGEHAAVFGKPAIAAAIDLRTYLLV-ETTTSDTPTVTLEFPDIHLNFKVQV 63

Query: 365 E 367
           +
Sbjct: 64  D 64



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 28/89 (31%), Positives = 43/89 (48%)
 Frame = +3

Query: 426 SWRLPHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSM 605
           +W  P  +D   H+      L L++     L   Q+ ++ SFLY++  +   +     S 
Sbjct: 79  NWSTPKTLDK--HIFDSLSSLALLEE--PGLTKVQQAAVVSFLYLYIHLCPPSVCEDSSN 134

Query: 606 DISMGSELTIGAGTGSSASFAVCLXGALI 692
            + + S L IGAG GSSAS  VCL   L+
Sbjct: 135 WV-VRSTLPIGAGLGSSASICVCLAAGLL 162


>UniRef50_UPI0000DB6B27 Cluster: PREDICTED: similar to Mevalonate
           kinase (MK); n=1; Apis mellifera|Rep: PREDICTED: similar
           to Mevalonate kinase (MK) - Apis mellifera
          Length = 359

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 24/37 (64%), Positives = 30/37 (81%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEV 295
           VSAPGKVIL GEH+VVYGKTA+A S+ LR+ +   E+
Sbjct: 6   VSAPGKVILFGEHAVVYGKTAVAASIDLRTVLNFTEL 42



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/55 (41%), Positives = 30/55 (54%)
 Frame = +3

Query: 528 QKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGALI 692
           QK SL +F Y    I     + +K   I + +EL I +G GSSASFAVCL    +
Sbjct: 81  QKLSLEAFFYTLIYIAQKEEMEIKPFQIQLNTELAINSGLGSSASFAVCLAACFV 135


>UniRef50_Q7PWI8 Cluster: ENSANGP00000021364; n=2; Culicidae|Rep:
           ENSANGP00000021364 - Anopheles gambiae str. PEST
          Length = 402

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 24/30 (80%), Positives = 26/30 (86%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRS 274
           VSAPGKVILHGEHSVVYG  AIA S+GL +
Sbjct: 11  VSAPGKVILHGEHSVVYGHPAIAGSIGLHT 40



 Score = 36.7 bits (81), Expect = 0.54
 Identities = 16/29 (55%), Positives = 21/29 (72%)
 Frame = +3

Query: 609 ISMGSELTIGAGTGSSASFAVCLXGALIQ 695
           +S+ SE++IGAG GSSAS+ VCL     Q
Sbjct: 143 LSLYSEMSIGAGLGSSASYGVCLAAGAYQ 171


>UniRef50_Q0UWF5 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 526

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 24/57 (42%), Positives = 39/57 (68%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 355
           VSAPGKVI++GEH+VV+GK AIA ++ LRS + +  ++  +   V +  P + ++ T
Sbjct: 37  VSAPGKVIVYGEHAVVHGKAAIAAAISLRSYLHVSFLSKSNR-TVKLRFPDIQMEHT 92



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
 Frame = +3

Query: 420 KFSWRLPHKIDHDYHLRRVEEYLHLIKPNF-DSLPNNQKNSLRSFLYVFSGIFGSTYLPV 596
           K+ + L   +D D  +  ++ ++  + P   +S+      S  SFLY+F  +      P 
Sbjct: 110 KYYYDLVTSLDPDL-MAAIQPFIDEVSPKAPESVRKIHHASACSFLYLFLSLASRKTPPC 168

Query: 597 KSMDISMGSELTIGAGTGSSASFAVCLXGALI 692
                ++ S + IGAG GSSAS +VCL  A++
Sbjct: 169 I---YTLRSTIPIGAGLGSSASISVCLSAAML 197


>UniRef50_Q4WP25 Cluster: Mevalonate kinase; n=15;
           Pezizomycotina|Rep: Mevalonate kinase - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 538

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 24/69 (34%), Positives = 44/69 (63%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIPL 364
           VSAPGKVI++GEH+VV+GK A+A ++ LRS +++  + +  +  + ++   + L  T  +
Sbjct: 94  VSAPGKVIVYGEHAVVHGKAAMAAAISLRSYLLVTTL-SKSQRTITMNFRDIGLDHTWNI 152

Query: 365 EPTVKSLFH 391
           +     +FH
Sbjct: 153 DELPWDVFH 161



 Score = 40.3 bits (90), Expect = 0.044
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
 Frame = +3

Query: 399 WHQGITGKFSWRLPHKIDHDYHLRRVEEYLHLIKPNF-DSLPNNQKNSLRSFLYVFSGIF 575
           +H     KF + L   +D +  +  ++ +   + P+  + +    + S  +FLY+F  + 
Sbjct: 160 FHHPSKKKFYYDLVTSLDPEL-VAAIQPHADAVSPDKPEDVRKIHRRSASAFLYLFLSL- 217

Query: 576 GSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGALI 692
           GS+  P      ++ S + IGAG GSSAS  VCL  AL+
Sbjct: 218 GSSQNP--GAIYTLRSTIPIGAGLGSSASVCVCLSAALL 254


>UniRef50_Q86AG7 Cluster: Similar to Rattus norvegicus (Rat).
           Mevalonate kinase; n=2; Dictyostelium discoideum|Rep:
           Similar to Rattus norvegicus (Rat). Mevalonate kinase -
           Dictyostelium discoideum (Slime mold)
          Length = 390

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 24/44 (54%), Positives = 34/44 (77%)
 Frame = +2

Query: 149 MLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 280
           M++  DN+  + VSAPGK+IL GEH+VV  KTAIA +L LR+++
Sbjct: 1   MISNQDNI--IQVSAPGKIILFGEHAVVLEKTAIASALSLRTTV 42



 Score = 37.1 bits (82), Expect = 0.41
 Identities = 20/52 (38%), Positives = 32/52 (61%)
 Frame = +3

Query: 540 LRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGALIQ 695
           + +FL++F  +   T    K+ +I + S+L IGAG GSSASF V +   L++
Sbjct: 107 IHTFLFLFCALTKCT----KAYNIKITSDLPIGAGLGSSASFCVSICAGLLK 154


>UniRef50_Q4TG59 Cluster: Chromosome undetermined SCAF3891, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF3891,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 173

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 29/62 (46%), Positives = 40/62 (64%), Gaps = 7/62 (11%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKT-------AIAVSLGLRSSIVIKEVNTPHEPAVHIHLPC 337
           + VSAPGK ILHGEH+VV+GK        A+AVSL LRS + ++  +T     V ++LP 
Sbjct: 1   IYVSAPGKAILHGEHAVVHGKVTSNKAKMALAVSLNLRSYLRLEATST---GTVGVNLPN 57

Query: 338 VD 343
           +D
Sbjct: 58  ID 59



 Score = 42.3 bits (95), Expect = 0.011
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +3

Query: 501 PNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLX 680
           PN D+  +   + L+ F    SG    T L    + +S+ SEL  GAG GSSA++ VCL 
Sbjct: 56  PNIDTFLHWNLSELKQFAPSVSGNEQLT-LGAAQLTVSVWSELPTGAGLGSSAAYTVCLA 114

Query: 681 GALI 692
            AL+
Sbjct: 115 AALL 118


>UniRef50_A2SR97 Cluster: Mevalonate kinase; n=4;
           Methanomicrobiales|Rep: Mevalonate kinase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 290

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 22/42 (52%), Positives = 29/42 (69%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEP 313
           SAPGKVIL GEHSVVYGK AIA+++  R  + ++      +P
Sbjct: 5   SAPGKVILFGEHSVVYGKPAIAMAIKPRVQVTVRHSRYYQKP 46


>UniRef50_Q09780 Cluster: Putative mevalonate kinase; n=1;
           Schizosaccharomyces pombe|Rep: Putative mevalonate
           kinase - Schizosaccharomyces pombe (Fission yeast)
          Length = 404

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 21/38 (55%), Positives = 28/38 (73%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVN 298
           VS+PGK IL GEH+VVYG TA+A ++ LRS   ++  N
Sbjct: 7   VSSPGKTILFGEHAVVYGATALAAAVSLRSYCKLQTTN 44



 Score = 33.5 bits (73), Expect = 5.1
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +3

Query: 486 LHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASF 665
           L L++   + L N +   + S +     +F S   P +   +++ S++ +GAG GSSA+ 
Sbjct: 85  LDLLQGLGELLKNEENGLIHSAMLCTLYLFTSLSSPSQGCTLTISSQVPLGAGLGSSATI 144

Query: 666 AVCLXGALI 692
           +V +  +L+
Sbjct: 145 SVVVATSLL 153


>UniRef50_Q8TT37 Cluster: Mevalonate kinase; n=5; Euryarchaeota|Rep:
           Mevalonate kinase - Methanosarcina acetivorans
          Length = 305

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 19/37 (51%), Positives = 29/37 (78%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 289
           +S SAPGK+ L GEH+VVYG+TAI  ++ LR+ + ++
Sbjct: 6   ISCSAPGKIYLFGEHAVVYGETAIGCAIELRTRVRVE 42


>UniRef50_P07277 Cluster: Mevalonate kinase; n=3;
           Saccharomycetales|Rep: Mevalonate kinase - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 443

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 22/40 (55%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTP 304
           SAPGKVI+ GEHS VY K A+A S+  LR+ ++I E + P
Sbjct: 8   SAPGKVIIFGEHSAVYNKPAVAASVSALRTYLLISESSAP 47


>UniRef50_Q50559 Cluster: Mevalonate kinase; n=2;
           Methanothermobacter thermautotrophicus str. Delta H|Rep:
           Mevalonate kinase - Methanobacterium thermoautotrophicum
          Length = 303

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 20/42 (47%), Positives = 28/42 (66%)
 Frame = +2

Query: 182 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPH 307
           S SAP K IL GEH+VVY K AIA ++  R ++ + E ++ H
Sbjct: 4   SASAPAKAILFGEHAVVYSKPAIAAAIDRRVTVTVSESSSTH 45


>UniRef50_Q0LHN3 Cluster: Mevalonate kinase; n=2; Chloroflexi
           (class)|Rep: Mevalonate kinase - Herpetosiphon
           aurantiacus ATCC 23779
          Length = 313

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/54 (42%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTPHEPAVHIHLPCVDL 346
           SAPGK+IL GEH+VVYG+ A+A+ +  LR+S+ ++    P    + +H P + L
Sbjct: 3   SAPGKLILAGEHAVVYGQPALAMPIAALRASVAVEP--APRGAGMTVHAPDLGL 54


>UniRef50_A0B6E3 Cluster: Mevalonate kinase; n=1; Methanosaeta
           thermophila PT|Rep: Mevalonate kinase - Methanosaeta
           thermophila (strain DSM 6194 / PT)
           (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 321

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/47 (40%), Positives = 33/47 (70%)
 Frame = +2

Query: 182 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVH 322
           + SAPGKVIL GEH+VV G  A+  ++ LR+ ++++++    E ++H
Sbjct: 3   AASAPGKVILFGEHAVVSGAPALGTAIDLRARVLVEDLPGKTEISIH 49


>UniRef50_Q9V187 Cluster: Mevalonate kinase; n=4;
           Thermococcaceae|Rep: Mevalonate kinase - Pyrococcus
           abyssi
          Length = 335

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/34 (61%), Positives = 26/34 (76%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSI 280
           V  SAP K+IL GEHSVVYGK AIA ++ LR+ +
Sbjct: 5   VLASAPAKIILFGEHSVVYGKPAIASAIDLRTYV 38


>UniRef50_Q58487 Cluster: Mevalonate kinase; n=1; Methanocaldococcus
           jannaschii|Rep: Mevalonate kinase - Methanococcus
           jannaschii
          Length = 312

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 20/36 (55%), Positives = 27/36 (75%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 292
           +  P KVIL GEH+VVYG  AI++++ L S+I IKE
Sbjct: 3   IETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKE 38


>UniRef50_Q7K2V9 Cluster: GH04687p; n=1; Drosophila
           melanogaster|Rep: GH04687p - Drosophila melanogaster
           (Fruit fly)
          Length = 390

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 18/37 (48%), Positives = 29/37 (78%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEV 295
           V +PGKVILHGEH+VVY + A+A  +GL +++  +++
Sbjct: 6   VHSPGKVILHGEHAVVYHRPALAAVVGLGTTLRFRQL 42


>UniRef50_Q756D2 Cluster: AER335Wp; n=3; Saccharomycetaceae|Rep:
           AER335Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 428

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/54 (42%), Positives = 31/54 (57%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQ 349
           SAPGKVI+ GEHS VY K AIA S+    + +  E +   + AV +  P +  Q
Sbjct: 19  SAPGKVIIFGEHSAVYNKPAIAASVSSLRTYLFVEADAESD-AVRMEFPDIGFQ 71



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 20/47 (42%), Positives = 29/47 (61%)
 Frame = +3

Query: 549 FLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGAL 689
           FLY+++ +       V+ +  ++ S L IGAG GSSAS AVCL  A+
Sbjct: 123 FLYIYTCLCRE----VQGVRFTVKSTLPIGAGLGSSASIAVCLALAM 165


>UniRef50_O27995 Cluster: Mevalonate kinase; n=1; Archaeoglobus
           fulgidus|Rep: Mevalonate kinase - Archaeoglobus fulgidus
          Length = 284

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 17/35 (48%), Positives = 27/35 (77%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 292
           SAPGK+IL GEH+VVYG+ A+  ++ LR  + +++
Sbjct: 4   SAPGKIILFGEHAVVYGRHAVVSAINLRCRVSVRK 38


>UniRef50_Q9HQI6 Cluster: Mevalonate kinase; n=5;
           Halobacteriaceae|Rep: Mevalonate kinase - Halobacterium
           salinarium (Halobacterium halobium)
          Length = 330

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 18/39 (46%), Positives = 27/39 (69%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 292
           T + SAPGKV L GEH+VVYG+ A+  ++  R+ + + E
Sbjct: 2   TTTSSAPGKVYLFGEHAVVYGEPAVPCAIERRAHVTVSE 40


>UniRef50_Q2HTL9 Cluster: Mevalonate and galactokinase; n=5; core
           eudicotyledons|Rep: Mevalonate and galactokinase -
           Medicago truncatula (Barrel medic)
          Length = 388

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 20/42 (47%), Positives = 30/42 (71%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTP 304
           V   APGK+IL GEH+VV+G TA+A S+ L + + ++  +TP
Sbjct: 3   VKARAPGKIILAGEHAVVHGSTAVASSIDLYTYVSLR-FSTP 43



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 18/53 (33%), Positives = 31/53 (58%)
 Frame = +3

Query: 534 NSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASFAVCLXGALI 692
           + + +FL+++S I G      K   + + S+L +G+G GSSA+F V L  A +
Sbjct: 113 SGVAAFLWLYSSIQG-----FKPATVVINSDLPLGSGLGSSAAFCVALAAAFL 160


>UniRef50_A1RYL2 Cluster: Mevalonate kinase; n=1; Thermofilum
           pendens Hrk 5|Rep: Mevalonate kinase - Thermofilum
           pendens (strain Hrk 5)
          Length = 322

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 19/38 (50%), Positives = 27/38 (71%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 301
           SAP KVIL GEH VV G+ AIA ++ LR+ + ++  +T
Sbjct: 7   SAPAKVILFGEHFVVEGQPAIAAAISLRAHVTVEPADT 44


>UniRef50_P46086 Cluster: Mevalonate kinase; n=8; Magnoliophyta|Rep:
           Mevalonate kinase - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 378

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 17/37 (45%), Positives = 27/37 (72%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 289
           V   APGK+IL GEH+VV+G TA+A ++ L + + ++
Sbjct: 3   VKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLR 39


>UniRef50_UPI000155611C Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein, partial - Ornithorhynchus anatinus
          Length = 269

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 26/85 (30%), Positives = 45/85 (52%)
 Frame = +3

Query: 438 PHKIDHDYHLRRVEEYLHLIKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISM 617
           P  +     + +++E+  L     DS    Q  +L +FLY+++ I G T      +D+++
Sbjct: 68  PSAVPTPEQMEKLKEFAGLAPGPLDS----QGLALLAFLYLYTAI-GGTDGAWPGVDVTV 122

Query: 618 GSELTIGAGTGSSASFAVCLXGALI 692
            SEL  G G GSSA+++ CL   L+
Sbjct: 123 WSELPPGGGLGSSAAYSACLAACLL 147


>UniRef50_A5UV63 Cluster: Mevalonate kinase; n=3;
           Chloroflexaceae|Rep: Mevalonate kinase - Roseiflexus sp.
           RS-1
          Length = 314

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 18/25 (72%), Positives = 22/25 (88%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSL 262
           SAPGK+IL GEH+VVYG+ AIA+ L
Sbjct: 4   SAPGKIILCGEHAVVYGRPAIAIPL 28


>UniRef50_A2E1U7 Cluster: Mevalonate kinase family protein; n=1;
           Trichomonas vaginalis G3|Rep: Mevalonate kinase family
           protein - Trichomonas vaginalis G3
          Length = 315

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 18/30 (60%), Positives = 23/30 (76%)
 Frame = +2

Query: 182 SVSAPGKVILHGEHSVVYGKTAIAVSLGLR 271
           S S PGKVIL GEH+VVYG+ A+A ++  R
Sbjct: 5   SFSFPGKVILFGEHAVVYGEAAVASAISRR 34


>UniRef50_A7DRD8 Cluster: Mevalonate kinase; n=1; Candidatus
           Nitrosopumilus maritimus SCM1|Rep: Mevalonate kinase -
           Candidatus Nitrosopumilus maritimus SCM1
          Length = 313

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 18/37 (48%), Positives = 26/37 (70%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVN 298
           SAPGKVIL GEH VVYG  AI  ++  R ++  ++++
Sbjct: 6   SAPGKVILFGEHFVVYGVKAILCAINKRIAVTAEKID 42


>UniRef50_UPI00015BB033 Cluster: mevalonate kinase; n=1; Ignicoccus
           hospitalis KIN4/I|Rep: mevalonate kinase - Ignicoccus
           hospitalis KIN4/I
          Length = 321

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 19/29 (65%), Positives = 21/29 (72%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSL 262
           +VS  AP KV L GEHSVVYGK AI  S+
Sbjct: 2   SVSARAPTKVTLFGEHSVVYGKPAIVFSM 30


>UniRef50_Q2NG06 Cluster: Putative mevalonate kinase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Putative
           mevalonate kinase - Methanosphaera stadtmanae (strain
           DSM 3091)
          Length = 322

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 17/28 (60%), Positives = 22/28 (78%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSL 262
           +   APGK+IL GEH+VVY K AIAV++
Sbjct: 3   IKAFAPGKIILFGEHTVVYKKPAIAVAI 30


>UniRef50_A5UN66 Cluster: Mevalonate kinase; n=1; Methanobrevibacter
           smithii ATCC 35061|Rep: Mevalonate kinase -
           Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
           861)
          Length = 320

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 20/38 (52%), Positives = 25/38 (65%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 301
           SAP K IL GEHSVVY + AIA ++  R+ + I E  T
Sbjct: 6   SAPAKTILFGEHSVVYDEPAIAGAVNKRAYVEITESKT 43


>UniRef50_A3H636 Cluster: Mevalonate kinase; n=1; Caldivirga
           maquilingensis IC-167|Rep: Mevalonate kinase -
           Caldivirga maquilingensis IC-167
          Length = 334

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 17/38 (44%), Positives = 27/38 (71%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKE 292
           V+ +APG V L GEH+VVYG+ AIA+++     + ++E
Sbjct: 6   VTATAPGVVKLFGEHAVVYGRPAIAMAINKGIKVTVEE 43


>UniRef50_Q74JA4 Cluster: Mevalonate kinase; n=7; Lactobacillus|Rep:
           Mevalonate kinase - Lactobacillus johnsonii
          Length = 305

 Score = 39.5 bits (88), Expect = 0.077
 Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTP 304
           + V A GKVIL GEHSVVYG  A+A+ +  L  +  ++E + P
Sbjct: 5   IEVKAHGKVILIGEHSVVYGYDALALPIQALNITTTVEETDGP 47


>UniRef50_Q2BIK0 Cluster: Mevalonate kinase, putative; n=1;
           Neptuniibacter caesariensis|Rep: Mevalonate kinase,
           putative - Neptuniibacter caesariensis
          Length = 327

 Score = 39.5 bits (88), Expect = 0.077
 Identities = 17/33 (51%), Positives = 24/33 (72%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSS 277
           +   APGK+IL GEHSVVYG  AIA ++  +++
Sbjct: 1   MKAQAPGKLILSGEHSVVYGAPAIATAVAQQAT 33


>UniRef50_Q8TWN9 Cluster: Mevalonate kinase; n=1; Methanopyrus
           kandleri|Rep: Mevalonate kinase - Methanopyrus kandleri
          Length = 328

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 18/28 (64%), Positives = 22/28 (78%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSL 262
           +SV AP K IL GEH+VVYG  A+AV+L
Sbjct: 3   ISVKAPLKAILAGEHAVVYGYPAVAVAL 30


>UniRef50_A2BL67 Cluster: Mevalonate kinase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Mevalonate kinase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 316

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 17/29 (58%), Positives = 23/29 (79%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRS 274
           SAP KVI+ GEH VV+G  A+A ++GLR+
Sbjct: 6   SAPAKVIVFGEHWVVHGGLALAAAIGLRA 34


>UniRef50_Q9Y946 Cluster: Mevalonate kinase; n=1; Aeropyrum
           pernix|Rep: Mevalonate kinase - Aeropyrum pernix
          Length = 324

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK 289
           SAPGKVI+ GEH VV G  AI  ++G R  + ++
Sbjct: 8   SAPGKVIIVGEHFVVRGSLAIVAAIGRRLRVTVR 41


>UniRef50_Q8L1I1 Cluster: Phosphomevalonate kinase; n=1; Paracoccus
           zeaxanthinifaciens|Rep: Phosphomevalonate kinase -
           Paracoccus zeaxanthinifaciens
          Length = 305

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 16/36 (44%), Positives = 23/36 (63%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVI 286
           +  SAPG V++ GEH+VVYG  AI   +  R+ + I
Sbjct: 5   IRASAPGSVMITGEHAVVYGHRAIVAGIEQRAHVTI 40


>UniRef50_A6G140 Cluster: Hydroxymethylglutaryl-CoA reductase; n=1;
           Plesiocystis pacifica SIR-1|Rep:
           Hydroxymethylglutaryl-CoA reductase - Plesiocystis
           pacifica SIR-1
          Length = 810

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 16/34 (47%), Positives = 26/34 (76%)
 Frame = +2

Query: 173 FTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRS 274
           +T +VSAPGK  L GE++V+YG +AI  ++ +R+
Sbjct: 43  YTGTVSAPGKAFLIGEYAVLYGHSAIVTAVDVRA 76


>UniRef50_Q8L1I2 Cluster: Mevalonate kinase; n=1; Paracoccus
           zeaxanthinifaciens|Rep: Mevalonate kinase - Paracoccus
           zeaxanthinifaciens
          Length = 378

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 15/24 (62%), Positives = 21/24 (87%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSL 262
           APGK+IL GEHSV+YG  A+A+++
Sbjct: 12  APGKLILSGEHSVLYGAPALAMAI 35


>UniRef50_A5EVP5 Cluster: GHMP kinase family protein; n=1;
           Dichelobacter nodosus VCS1703A|Rep: GHMP kinase family
           protein - Dichelobacter nodosus (strain VCS1703A)
          Length = 303

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET 355
           T+  SA G V++ GEH+VVYG+ AI  ++  R  + +   N   +  + IH    D + T
Sbjct: 2   TIETSASGSVMICGEHAVVYGQPAIVAAIAQRIRVRLTPRN---DDKITIHSALGDYEST 58


>UniRef50_A5EUV5 Cluster: GHMP kinase family protein; n=1;
           Dichelobacter nodosus VCS1703A|Rep: GHMP kinase family
           protein - Dichelobacter nodosus (strain VCS1703A)
          Length = 352

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 16/24 (66%), Positives = 20/24 (83%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSL 262
           APGK+IL GEH+VVYG  AI V++
Sbjct: 8   APGKLILSGEHAVVYGAPAIVVAV 31


>UniRef50_Q6LXL5 Cluster: Mevalonate kinase; n=5; Methanococcus|Rep:
           Mevalonate kinase - Methanococcus maripaludis
          Length = 317

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +2

Query: 182 SVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQETIP 361
           ++  P K+IL GEH+VV G  AI+++L L+++  I+E    +   + I L  VDL E   
Sbjct: 3   TIKTPSKIILFGEHAVVDGYPAISMALDLKTTGEIEE----NFDTISIDL--VDLNEIFE 56

Query: 362 LEP-TVKSLFHPKLAP 406
           + P  +K+L     +P
Sbjct: 57  ITPELIKNLEISNFSP 72


>UniRef50_A0E671 Cluster: Chromosome undetermined scaffold_8, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_8,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 288

 Score = 37.1 bits (82), Expect = 0.41
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVI 286
           V AP K+I+ GEHSVVYG  A+  ++   ++I I
Sbjct: 3   VRAPAKIIISGEHSVVYGHKALCAAINKYTTIKI 36


>UniRef50_Q7QVN5 Cluster: GLP_305_18405_19430; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_305_18405_19430 - Giardia lamblia
           ATCC 50803
          Length = 341

 Score = 36.3 bits (80), Expect = 0.72
 Identities = 18/31 (58%), Positives = 21/31 (67%)
 Frame = +2

Query: 185 VSAPGKVILHGEHSVVYGKTAIAVSLGLRSS 277
           V  P K IL GEHSVVYG   IA++L L +S
Sbjct: 13  VRTPLKAILSGEHSVVYGHPCIAMALDLYTS 43


>UniRef50_Q22LZ8 Cluster: ATPase, AAA family protein; n=1;
           Tetrahymena thermophila SB210|Rep: ATPase, AAA family
           protein - Tetrahymena thermophila SB210
          Length = 741

 Score = 36.3 bits (80), Expect = 0.72
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
 Frame = +2

Query: 110 LVNFACAYY-IKRTMLTAVDNLFTVSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVI 286
           L+N+  AY  I + M+ ++D + T   S    +++ G  S+  GKTAIA +  L+S I  
Sbjct: 508 LINYGEAYERISKQMIQSIDYVKTSENSLIHSILIEG--SIGTGKTAIAAAFALKSDITY 565

Query: 287 KEVNTP 304
            ++ TP
Sbjct: 566 VKILTP 571


>UniRef50_Q83DT4 Cluster: Phosphomevalonate kinase, putative; n=2;
           Coxiella burnetii|Rep: Phosphomevalonate kinase,
           putative - Coxiella burnetii
          Length = 313

 Score = 35.9 bits (79), Expect = 0.95
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIK----EVNTPHEPAVHIHLPCVDLQETI 358
           APG ++L GE++V+ GKTAI  ++    SI +     E      P   + L C  ++ + 
Sbjct: 7   APGSLMLLGEYAVLQGKTAIVAAIDKFISISLSPRHDEKINIDSPLGKLTLDCQSIKLSP 66

Query: 359 PLEPTVKSLFHPKLAPGXNRQILLEITP 442
           P E  + +L   KL  G +  I   + P
Sbjct: 67  PFEFVLAALASKKLPSGCDINIQSTLPP 94


>UniRef50_Q03FN7 Cluster: Mevalonate kinase; n=1; Pediococcus
           pentosaceus ATCC 25745|Rep: Mevalonate kinase -
           Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 306

 Score = 35.9 bits (79), Expect = 0.95
 Identities = 17/38 (44%), Positives = 28/38 (73%), Gaps = 1/38 (2%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVN 298
           S+  K+IL GEHSVVYG+ AIA+ +  +++++ I+  N
Sbjct: 7   SSNSKIILIGEHSVVYGQPAIALPIRNVKTTVKIQPTN 44


>UniRef50_A6G138 Cluster: Mevalonate kinase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Mevalonate kinase - Plesiocystis
           pacifica SIR-1
          Length = 320

 Score = 35.9 bits (79), Expect = 0.95
 Identities = 22/52 (42%), Positives = 28/52 (53%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDL 346
           A GK+IL GEHSVVYG  A+A  L  R  I+          A+ + +P  DL
Sbjct: 11  ACGKIILLGEHSVVYGHPALAAGLS-RGLILRARPLDGRGGAMELSIPAWDL 61


>UniRef50_A2U564 Cluster: Mevalonate kinase; n=1; Bacillus coagulans
           36D1|Rep: Mevalonate kinase - Bacillus coagulans 36D1
          Length = 314

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 16/27 (59%), Positives = 22/27 (81%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAV 256
           T + +A GK+IL GEH+VVYG+ AIA+
Sbjct: 8   TATGTAHGKLILAGEHAVVYGQPAIAL 34


>UniRef50_Q9FD69 Cluster: Mevalonate kinase; n=4; Enterococcus|Rep:
           Mevalonate kinase - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 314

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 15/21 (71%), Positives = 18/21 (85%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIA 253
           A GK+IL GEH+VVYG+ AIA
Sbjct: 11  ATGKIILMGEHAVVYGEPAIA 31


>UniRef50_Q2BIJ9 Cluster: GHMP kinase; n=1; Neptuniibacter
           caesariensis|Rep: GHMP kinase - Neptuniibacter
           caesariensis
          Length = 309

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 12/29 (41%), Positives = 22/29 (75%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGKTAIAVSL 262
           T+ V  PG ++L GEH+V++G+ A+A ++
Sbjct: 3   TIKVKVPGSIMLMGEHAVLFGEKALACAV 31


>UniRef50_Q2GZQ7 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 460

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
 Frame = +2

Query: 176 TVSVSAPGKVILHGEHSVVYGK-TAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQE 352
           TV VSAPGKV+L G + V+  K T +   L  R  ++ +E++T    +  +HL  + +Q 
Sbjct: 12  TVVVSAPGKVLLAGGYIVLDRKHTGLVFGLSARIHVLAQEIHT----SAGVHLREIVVQS 67

Query: 353 TIPLEPTVKSLFH 391
              L  T K  +H
Sbjct: 68  PQFLNATWKYGYH 80


>UniRef50_Q97UL6 Cluster: (Phospho) mevalonate kinase, putative;
           n=4; Sulfolobaceae|Rep: (Phospho) mevalonate kinase,
           putative - Sulfolobus solfataricus
          Length = 323

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 14/39 (35%), Positives = 26/39 (66%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEV 295
           + VSAPGK++  G +SVV+G  +  +++  R S  ++E+
Sbjct: 2   IKVSAPGKILWIGSYSVVFGGISHVIAVNKRVSCSLREI 40


>UniRef50_A3DL21 Cluster: Mevalonate kinase; n=1; Staphylothermus
           marinus F1|Rep: Mevalonate kinase - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 324

 Score = 34.3 bits (75), Expect = 2.9
 Identities = 17/38 (44%), Positives = 23/38 (60%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNT 301
           +AP KVIL GEH VV  K AI  ++ L +   I E+ +
Sbjct: 5   AAPAKVILFGEHFVVKDKPAIVTAVNLYAKTCITELES 42


>UniRef50_Q38X71 Cluster: Mevalonate kinase; n=1; Lactobacillus
           sakei subsp. sakei 23K|Rep: Mevalonate kinase -
           Lactobacillus sakei subsp. sakei (strain 23K)
          Length = 315

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 16/42 (38%), Positives = 29/42 (69%), Gaps = 1/42 (2%)
 Frame = +2

Query: 200 KVILHGEHSVVYGKTAIAVSL-GLRSSIVIKEVNTPHEPAVH 322
           K+IL GEH+VVYG+ AIA+ +  +++++ +    T  EP ++
Sbjct: 11  KIILIGEHAVVYGQPAIALPIFAVQTTVRVTAQPTLSEPLIN 52


>UniRef50_A5VK03 Cluster: Mevalonate kinase; n=2; Lactobacillus
           reuteri|Rep: Mevalonate kinase - Lactobacillus reuteri
           F275
          Length = 316

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 15/21 (71%), Positives = 18/21 (85%)
 Frame = +2

Query: 200 KVILHGEHSVVYGKTAIAVSL 262
           K+IL GEHSVVYG+ AIA+ L
Sbjct: 13  KIILMGEHSVVYGQPAIALPL 33


>UniRef50_A4VT18 Cluster: Mevalonate kinase; n=4; Streptococcus|Rep:
           Mevalonate kinase - Streptococcus suis (strain 05ZYH33)
          Length = 317

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 15/22 (68%), Positives = 18/22 (81%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAV 256
           A GK+IL GEH+VVYG  AIA+
Sbjct: 13  ANGKIILMGEHAVVYGHPAIAM 34


>UniRef50_Q8F618 Cluster: Putative uncharacterized protein; n=2;
           Leptospira interrogans|Rep: Putative uncharacterized
           protein - Leptospira interrogans
          Length = 77

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
 Frame = +3

Query: 453 HDYHLRRVEEYLHLIKPN-FDSLPNNQKNSLRSFLYVFS 566
           +DYHLR +E +L  +K N F S     + SL+SFLYV S
Sbjct: 2   YDYHLRVLERFLKNLKGNDFCSFYKLFRFSLQSFLYVMS 40


>UniRef50_Q83DT3 Cluster: Mevalonate kinase, putative; n=3; Coxiella
           burnetii|Rep: Mevalonate kinase, putative - Coxiella
           burnetii
          Length = 340

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 13/23 (56%), Positives = 19/23 (82%)
 Frame = +2

Query: 194 PGKVILHGEHSVVYGKTAIAVSL 262
           P K+IL GEH+VVYG  A++V++
Sbjct: 11  PAKLILSGEHAVVYGHPALSVAI 33


>UniRef50_Q8H912 Cluster: Putative zinc knuckle domain containing
           protein; n=3; Oryza sativa (japonica
           cultivar-group)|Rep: Putative zinc knuckle domain
           containing protein - Oryza sativa subsp. japonica (Rice)
          Length = 910

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 2/56 (3%)
 Frame = +1

Query: 226 GRVRKNCDRCQPRPKELHSDKGS--KHSTRTSSPHTFAVRGSTGDHSIGADSQKSV 387
           GR R + D CQ R +  HS + S    S RT SP +   RG  G    G  + K V
Sbjct: 575 GRQRAHGDGCQGRSRTRHSSRCSCRCRSRRTRSPSSLTPRGQDGTGDAGGATTKVV 630


>UniRef50_Q7XJS3 Cluster: At2g17440 protein; n=3; Brassicaceae|Rep:
           At2g17440 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 526

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 15/27 (55%), Positives = 18/27 (66%)
 Frame = -2

Query: 694 CINAPXRQTAKDAELPVPAPMVSSDPI 614
           CI +P   TA    +PVPAP+VSSD I
Sbjct: 109 CIASPNSTTALPRSVPVPAPVVSSDEI 135


>UniRef50_Q60ED2 Cluster: Putative uncharacterized protein
           OSJNBa0002D18.17; n=5; Oryza sativa|Rep: Putative
           uncharacterized protein OSJNBa0002D18.17 - Oryza sativa
           subsp. japonica (Rice)
          Length = 911

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 13/33 (39%), Positives = 20/33 (60%)
 Frame = -1

Query: 365 PMEWSPVDPRTANVCGLLVRVECLLPLSLWSSL 267
           P+E   V  + +N CG LVR  CL+ + LW ++
Sbjct: 131 PVEPPIVQSKFSNTCGTLVRTHCLINVKLWETV 163


>UniRef50_Q8SQK4 Cluster: MEVALONATE KINASE; n=1; Encephalitozoon
           cuniculi|Rep: MEVALONATE KINASE - Encephalitozoon
           cuniculi
          Length = 276

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 18/54 (33%), Positives = 29/54 (53%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQE 352
           +P KVIL GEH V+ G   +AV++ +   + +K  +      +  +  CVDL E
Sbjct: 7   SPLKVILFGEHGVLSGGRCLAVAIDVYGYLAMKSSSINKAIIIDTNGNCVDLIE 60


>UniRef50_Q08UJ8 Cluster: Mevalonate kinase; n=2;
           Cystobacterineae|Rep: Mevalonate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 310

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 15/19 (78%), Positives = 16/19 (84%)
 Frame = +2

Query: 197 GKVILHGEHSVVYGKTAIA 253
           GKVIL GEHSVVYG  A+A
Sbjct: 14  GKVILLGEHSVVYGHPALA 32


>UniRef50_Q031R4 Cluster: Mevalonate kinase; n=3; Lactococcus
           lactis|Rep: Mevalonate kinase - Lactococcus lactis
           subsp. cremoris (strain SK11)
          Length = 310

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +2

Query: 191 APGKVILHGEHSVVYGKTAIAVSLGLRSSIV 283
           A  K+IL GEHSVVYG+ AIA+ + +  + V
Sbjct: 11  AHSKLILIGEHSVVYGQPAIALPVTILKTTV 41


>UniRef50_Q6C026 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
           Similarity - Yarrowia lipolytica (Candida lipolytica)
          Length = 273

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
 Frame = +2

Query: 206 ILHGEHSVVYGKTAIAVSLGLRSSIVIKEVNTPHEPAVHIHLPCVDLQET-IPLEPTVKS 382
           +L G+  ++Y K    V   +    ++  ++ P   ++ +H     L++T +P+E  +K 
Sbjct: 110 LLGGKALLLYRKQKNQVLPWVELKRLVHTLDKPVLRSIAVHKELAKLEDTDLPIEYRIKM 169

Query: 383 LFH--PKLAPG--XNRQI-LLEITPQNRP*LSLAKGGGIPAFDQ 499
           + H  P+L P    +R + ++ I P+    +  A  GGI +FDQ
Sbjct: 170 IRHWEPQLDPSPLGDRVVEVIRIIPEKEADIMKAVEGGISSFDQ 213


>UniRef50_Q8ZTT2 Cluster: Mevalonate kinase; n=4; Pyrobaculum|Rep:
           Mevalonate kinase - Pyrobaculum aerophilum
          Length = 314

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 14/28 (50%), Positives = 19/28 (67%)
 Frame = +2

Query: 179 VSVSAPGKVILHGEHSVVYGKTAIAVSL 262
           V +  P  V L GEH+VVYGK AI+ ++
Sbjct: 2   VKIFVPAAVKLFGEHAVVYGKPAISAAI 29


>UniRef50_Q1WU40 Cluster: Mevalonate kinase; n=1; Lactobacillus
           salivarius subsp. salivarius UCC118|Rep: Mevalonate
           kinase - Lactobacillus salivarius subsp. salivarius
           (strain UCC118)
          Length = 314

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 15/25 (60%), Positives = 19/25 (76%)
 Frame = +2

Query: 188 SAPGKVILHGEHSVVYGKTAIAVSL 262
           S+  K+IL GEH+VVYG  AIA+ L
Sbjct: 10  SSHAKIILIGEHAVVYGHPAIALPL 34


>UniRef50_A3HYY0 Cluster: Galactokinase; n=1; Algoriphagus sp.
           PR1|Rep: Galactokinase - Algoriphagus sp. PR1
          Length = 382

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +3

Query: 591 PVKSMDISMGSELTIGAGTGSSASFAVCLXGAL 689
           PVK  DI  G ++ +G+G  SSA+ +V +  A+
Sbjct: 103 PVKGFDIVFGGDIPVGSGLSSSAALSVAIGTAI 135


>UniRef50_Q9VR26 Cluster: CG3294-PA, isoform A; n=4; Sophophora|Rep:
           CG3294-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 446

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 16/41 (39%), Positives = 17/41 (41%)
 Frame = +1

Query: 235 RKNCDRCQPRPKELHSDKGSKHSTRTSSPHTFAVRGSTGDH 357
           R   DR   R K  HS  GS H  R S  H      +T DH
Sbjct: 400 RSRSDRSSVRSKREHSSSGSSHDDRRSKRHHHHHNSTTPDH 440


>UniRef50_Q8TQ19 Cluster: Putative uncharacterized protein; n=2;
           Methanosarcina|Rep: Putative uncharacterized protein -
           Methanosarcina acetivorans
          Length = 225

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 19/57 (33%), Positives = 29/57 (50%)
 Frame = +3

Query: 495 IKPNFDSLPNNQKNSLRSFLYVFSGIFGSTYLPVKSMDISMGSELTIGAGTGSSASF 665
           I+  FD++        R F+  F   +G+T + V S+     S L IGAGTG  ++F
Sbjct: 4   IQQKFDAISKKYDEQRRKFIPCFDDFYGAT-VSVASVYTENPSILDIGAGTGLLSAF 59


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 733,548,386
Number of Sequences: 1657284
Number of extensions: 15840500
Number of successful extensions: 44906
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 42986
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44889
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54958682807
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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