Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P01_F_A07
(782 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 149 1e-35
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 149 1e-35
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 149 1e-35
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 149 1e-35
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 86 1e-16
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 84 5e-16
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 84 5e-16
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 84 5e-16
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 84 5e-16
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 84 5e-16
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 84 6e-16
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 84 6e-16
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 81 4e-15
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 81 4e-15
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 81 4e-15
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 79 1e-14
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 79 1e-14
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 79 1e-14
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 79 1e-14
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 79 1e-14
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 79 1e-14
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 79 2e-14
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 79 2e-14
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 77 7e-14
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 77 7e-14
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 77 7e-14
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 77 7e-14
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 77 7e-14
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 77 7e-14
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 77 7e-14
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 77 1e-13
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 75 3e-13
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 75 3e-13
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 75 3e-13
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 75 3e-13
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 75 4e-13
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 75 4e-13
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 74 7e-13
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 74 7e-13
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 74 7e-13
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 74 7e-13
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 74 7e-13
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 74 7e-13
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 74 7e-13
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 74 7e-13
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 74 7e-13
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 74 7e-13
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 73 2e-12
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 72 2e-12
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 72 3e-12
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 71 4e-12
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 71 4e-12
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 71 6e-12
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 71 6e-12
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 70 8e-12
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 70 8e-12
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 70 8e-12
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 70 8e-12
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 70 8e-12
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 70 8e-12
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 70 8e-12
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 70 8e-12
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 70 1e-11
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 69 2e-11
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 69 2e-11
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 69 3e-11
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 68 4e-11
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 68 4e-11
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 68 4e-11
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 57 8e-08
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 57 8e-08
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 57 8e-08
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 40 0.013
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 40 0.013
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 40 0.013
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 40 0.013
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 40 0.013
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 40 0.013
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 40 0.013
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 40 0.013
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 40 0.013
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 40 0.013
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 40 0.013
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 37 0.071
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 37 0.071
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 37 0.094
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 37 0.094
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 37 0.094
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 37 0.094
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.16
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 36 0.16
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 36 0.16
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 36 0.16
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.16
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 36 0.16
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 36 0.16
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 36 0.22
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 36 0.22
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 36 0.22
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 36 0.22
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 36 0.22
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 35 0.38
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 35 0.38
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 31 3.5
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 31 3.5
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 31 3.5
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 31 3.5
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 31 4.7
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 149 bits (360), Expect = 1e-35
Identities = 65/159 (40%), Positives = 103/159 (64%), Gaps = 2/159 (1%)
Frame = +2
Query: 305 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 484
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 658
G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 659 MSECTVEILLETAMGVSKSTQXQSGFXYAMAVMKMCDIL 775
++ C ++I+ ETAMG + Q Y AV +M +++
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 149 bits (360), Expect = 1e-35
Identities = 65/159 (40%), Positives = 103/159 (64%), Gaps = 2/159 (1%)
Frame = +2
Query: 305 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 484
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 658
G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 659 MSECTVEILLETAMGVSKSTQXQSGFXYAMAVMKMCDIL 775
++ C ++I+ ETAMG + Q Y AV +M +++
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 149 bits (360), Expect = 1e-35
Identities = 65/159 (40%), Positives = 103/159 (64%), Gaps = 2/159 (1%)
Frame = +2
Query: 305 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 484
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 50 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 109
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 658
G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y
Sbjct: 110 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 169
Query: 659 MSECTVEILLETAMGVSKSTQXQSGFXYAMAVMKMCDIL 775
++ C ++I+ ETAMG + Q Y AV +M +++
Sbjct: 170 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 208
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 149 bits (360), Expect = 1e-35
Identities = 65/159 (40%), Positives = 103/159 (64%), Gaps = 2/159 (1%)
Frame = +2
Query: 305 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 484
+ F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL
Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 658
G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191
Query: 659 MSECTVEILLETAMGVSKSTQXQSGFXYAMAVMKMCDIL 775
++ C ++I+ ETAMG + Q Y AV +M +++
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 86.2 bits (204), Expect = 1e-16
Identities = 47/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
+N Q SA Y IW+GP + + L P + I ++ I + RF KPWL
Sbjct: 9 KNSTQMSATYSQGFT--IWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 66
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASN-FDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D
Sbjct: 67 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 126
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 127 EHISLMTLDSL 137
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 46/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASN-FDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 192
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 193 EHISLMTLDSL 203
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 46/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 193 EHISLMTLDSL 203
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 46/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 193 EHISLMTLDSL 203
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 46/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 193 EHISLMTLDSL 203
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 84.2 bits (199), Expect = 5e-16
Identities = 46/131 (35%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 314 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 484
++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL
Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 652
G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D
Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192
Query: 653 DYMSECTVEIL 685
+++S T++ L
Sbjct: 193 EHISLMTLDSL 203
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 83.8 bits (198), Expect = 6e-16
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + DK ++ AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
+ Q + Y A++++
Sbjct: 209 SFESNCQEKPS-EYIAAILEL 228
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 83.8 bits (198), Expect = 6e-16
Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR
Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + DK ++ AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
+ Q + Y A++++
Sbjct: 209 SFESNCQEKPS-EYIAAILEL 228
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.0 bits (191), Expect = 4e-15
Identities = 46/153 (30%), Positives = 84/153 (54%), Gaps = 7/153 (4%)
Frame = +2
Query: 326 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 496
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 497 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 664
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 665 ECTVEILLETAMGVSKSTQXQSGFXYAMAVMKM 763
T++ L + + + Q + Y A++++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.0 bits (191), Expect = 4e-15
Identities = 46/153 (30%), Positives = 84/153 (54%), Gaps = 7/153 (4%)
Frame = +2
Query: 326 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 496
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 497 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 664
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 665 ECTVEILLETAMGVSKSTQXQSGFXYAMAVMKM 763
T++ L + + + Q + Y A++++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 81.0 bits (191), Expect = 4e-15
Identities = 46/153 (30%), Positives = 84/153 (54%), Gaps = 7/153 (4%)
Frame = +2
Query: 326 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 496
+K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144
Query: 497 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 664
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 665 ECTVEILLETAMGVSKSTQXQSGFXYAMAVMKM 763
T++ L + + + Q + Y A++++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/139 (30%), Positives = 75/139 (53%), Gaps = 7/139 (5%)
Frame = +2
Query: 368 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 538
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 706
+ P FH N+LK ++ +FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 707 SKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 211 DSHCQEKPS-EYIAAILEL 228
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/139 (30%), Positives = 75/139 (53%), Gaps = 7/139 (5%)
Frame = +2
Query: 368 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 538
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 706
+ P FH N+LK ++ +FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 707 SKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 211 DSHCQEKPS-EYIAAILEL 228
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/139 (30%), Positives = 75/139 (53%), Gaps = 7/139 (5%)
Frame = +2
Query: 368 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 538
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 706
+ P FH N+LK ++ +FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 707 SKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 211 DSHCQEKPS-EYIAAILEL 228
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 79.4 bits (187), Expect = 1e-14
Identities = 64/208 (30%), Positives = 102/208 (49%), Gaps = 9/208 (4%)
Frame = +2
Query: 167 LVPAVILW-YAYWRMSRR-RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSAD 340
L+ ++ W YA++ RR R + K N L V + + R + Q A
Sbjct: 30 LLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGH------LGLVTPTEEGLRVLTQLVAT 83
Query: 341 YDHESVVKIWIGPRL-LVFLYDPRDVE-VILSSHVYIDK-AEEYRFFKPWLGNGLLISTG 511
Y + V+ W+GP ++ L P V VI +S DK Y+ KPWLG+GLL+S G
Sbjct: 84 YP-QGFVR-WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVG 141
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANS---RAVVDKLKKEASN-FDCHDYMSECTVE 679
KWR HR+L+ P FH N+LK +I +F+ ++ A +L E S D +++S T++
Sbjct: 142 DKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLD 201
Query: 680 ILLETAMGVSKSTQXQSGFXYAMAVMKM 763
L + + Q + Y A+M++
Sbjct: 202 SLQKCIFSFDSNCQEKPS-EYITAIMEL 228
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/139 (30%), Positives = 75/139 (53%), Gaps = 7/139 (5%)
Frame = +2
Query: 368 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 538
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 706
+ P FH N+LK ++ +FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 707 SKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 211 DSHCQEKPS-EYIAAILEL 228
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 79.4 bits (187), Expect = 1e-14
Identities = 42/139 (30%), Positives = 75/139 (53%), Gaps = 7/139 (5%)
Frame = +2
Query: 368 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 538
W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++
Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 706
+ P FH N+LK ++ +FN + + K L E S D +++S T++ L +
Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210
Query: 707 SKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 211 DSHCQEKPS-EYIAAILEL 228
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 79.0 bits (186), Expect = 2e-14
Identities = 45/153 (29%), Positives = 83/153 (54%), Gaps = 7/153 (4%)
Frame = +2
Query: 326 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 496
+K D H V+ +W+GP L L+ L P ++ +L + ++ Y F KPWLG+GL
Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGL 144
Query: 497 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 664
L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204
Query: 665 ECTVEILLETAMGVSKSTQXQSGFXYAMAVMKM 763
T++ L + + + Q + Y A++++
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 79.0 bits (186), Expect = 2e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGPRLLVFLY-DPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP V + P + ++++ I ++ Y F KPWLG+GLL+S G+KW HR
Sbjct: 89 KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 77.0 bits (181), Expect = 7e-14
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 76.6 bits (180), Expect = 1e-13
Identities = 41/141 (29%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 700
+++ P FH N+LK ++ +FN + + K + AS D +++S T++ L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 701 GVSKSTQXQSGFXYAMAVMKM 763
Q + Y A++++
Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 75 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 134
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 135 ETNCQTNSTHDPYAKAIFELSKII 158
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 8/144 (5%)
Frame = +2
Query: 368 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 538
WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 706
+ P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A
Sbjct: 139 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSK 198
Query: 707 SKSTQXQSGFX-YAMAVMKMCDIL 775
+ Q S YA A+ ++ I+
Sbjct: 199 ETNCQTNSTHDPYAKAIFELSKII 222
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 74.5 bits (175), Expect = 4e-13
Identities = 31/80 (38%), Positives = 51/80 (63%), Gaps = 3/80 (3%)
Frame = +2
Query: 362 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 532
K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 533 KLIAPTFHLNVLKSFIDLFN 592
+++ P FH N+LK ++ +FN
Sbjct: 149 RMLTPAFHFNILKPYMKIFN 168
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 73.7 bits (173), Expect = 7e-13
Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 715
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207
Query: 716 TQ-XQSGFXYAMAVMKMCDIL 775
Q ++ Y A+ + +++
Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 72.5 bits (170), Expect = 2e-12
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 5/146 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ-XQSGFXYAMAVMKMCDIL 775
S Q ++ Y A+ + ++
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLSSLV 228
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 72.1 bits (169), Expect = 2e-12
Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 4/114 (3%)
Frame = +2
Query: 368 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 544
W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++
Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147
Query: 545 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETA 697
P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 71.7 bits (168), Expect = 3e-12
Identities = 42/146 (28%), Positives = 76/146 (52%), Gaps = 5/146 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ-XQSGFXYAMAVMKMCDIL 775
S Q ++ Y A+ + +++
Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNNLV 228
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 71.3 bits (167), Expect = 4e-12
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 71.3 bits (167), Expect = 4e-12
Identities = 38/143 (26%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQDP-KSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 70.5 bits (165), Expect = 6e-12
Identities = 57/214 (26%), Positives = 99/214 (46%), Gaps = 7/214 (3%)
Frame = +2
Query: 134 TFSAINLFYVLLVPAV-ILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVG-GSAD 307
+FS++ L+ L+ + L + + RR L + DK +ALE GS D
Sbjct: 9 SFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALEIQETGSLD 68
Query: 308 IFRNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPW 481
+V + + + +W G + + +Y+P + + S KA + Y FF W
Sbjct: 69 ---KVVSWAHQFPYAH--PLWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQW 121
Query: 482 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCH 652
+G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 122 IGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIF 181
Query: 653 DYMSECTVEILLETAMGVSKSTQXQSGFXYAMAV 754
+ + L++ G + Y +AV
Sbjct: 182 CDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAV 215
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/143 (26%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ S + ++S T+ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 70.1 bits (164), Expect = 8e-12
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 70.1 bits (164), Expect = 8e-12
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 70.1 bits (164), Expect = 8e-12
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 70.1 bits (164), Expect = 8e-12
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 5/143 (3%)
Frame = +2
Query: 359 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 535
V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 536 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 706
++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 707 SKSTQXQSGF-XYAMAVMKMCDI 772
S Q S Y AV + I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 70.1 bits (164), Expect = 8e-12
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGVS 709
+ P FH +VLK ++ +F ++R ++DK ++ E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCTFGRG 200
Query: 710 KSTQXQSGFXYAMAV 754
+ Y +AV
Sbjct: 201 DTGLGHRDSSYYLAV 215
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.9 bits (161), Expect = 2e-11
Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 703
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 68.9 bits (161), Expect = 2e-11
Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 703
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.9 bits (161), Expect = 2e-11
Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 703
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.9 bits (161), Expect = 2e-11
Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Frame = +2
Query: 365 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 538
+W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL
Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140
Query: 539 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 703
+ P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL YRF P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYGLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 68.5 bits (160), Expect = 3e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Frame = +2
Query: 353 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 529
S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H
Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142
Query: 530 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 700
R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A
Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
Query: 701 GVSKSTQ 721
S Q
Sbjct: 203 SHQGSIQ 209
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 56.8 bits (131), Expect = 8e-08
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +2
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 655
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 656 YMSECTVEILLETAMG 703
+ + L++ G
Sbjct: 168 DVGHMALNTLMKCTFG 183
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 56.8 bits (131), Expect = 8e-08
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +2
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 655
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 656 YMSECTVEILLETAMG 703
+ + L++ G
Sbjct: 168 DVGHMALNTLMKCTFG 183
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 56.8 bits (131), Expect = 8e-08
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +2
Query: 485 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 655
G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 656 YMSECTVEILLETAMG 703
+ + L++ G
Sbjct: 168 DVGHMALNTLMKCTFG 183
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 511
H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123
Query: 512 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 682
++W+ R L++PTF LK + + +V L++EA D ++++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 683 LLETAMGVS 709
+ T+ GV+
Sbjct: 184 ITSTSFGVN 192
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 37.1 bits (82), Expect = 0.071
Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 374 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 547
G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 135
Query: 548 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
TF LK + + +V L++EA D +++++ T+ GV+
Sbjct: 136 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 192
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 37.1 bits (82), Expect = 0.071
Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Frame = +2
Query: 374 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 547
G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P
Sbjct: 4 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62
Query: 548 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
TF LK + + +V L++EA D +++++ T+ GV+
Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 119
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.094
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 386 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 559
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 560 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.094
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 386 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 559
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 560 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 36.7 bits (81), Expect = 0.094
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 386 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 559
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 560 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.094
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%)
Frame = +2
Query: 386 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 559
++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF
Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139
Query: 560 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
LK + + +V L++EA +++++ T+ GVS
Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 365 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 541
++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+
Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133
Query: 542 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 709
+P F K + + + +V L++EA N + D+ T++++ T GV+
Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 35.5 bits (78), Expect = 0.22
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 299 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 472
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 473 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 637
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 35.5 bits (78), Expect = 0.22
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 299 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 472
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 473 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 637
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 35.5 bits (78), Expect = 0.22
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 299 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 472
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 473 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 637
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 35.5 bits (78), Expect = 0.22
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 299 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 472
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 473 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 637
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 35.5 bits (78), Expect = 0.22
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = +2
Query: 299 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 472
S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF
Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105
Query: 473 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 637
GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S
Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 514
H+ K+W G + ++ + DP ++++L Y F ++ + + I+ +
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 515 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 685
+W+ R L++PTF LK + + +V L++E D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 686 LETAMGVS 709
++ GV+
Sbjct: 185 TSSSFGVN 192
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 34.7 bits (76), Expect = 0.38
Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Frame = +2
Query: 347 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 514
H+ K+W G + ++ + DP ++++L Y F ++ + + I+ +
Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124
Query: 515 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 685
+W+ R L++PTF LK + + +V L++E D +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184
Query: 686 LETAMGVS 709
++ GV+
Sbjct: 185 TSSSFGVN 192
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 31.5 bits (68), Expect = 3.5
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 479 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 649
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 650 HDYMSECTVEILLETAMGVS 709
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 31.5 bits (68), Expect = 3.5
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 479 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 649
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 650 HDYMSECTVEILLETAMGVS 709
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 31.5 bits (68), Expect = 3.5
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 479 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 649
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 650 HDYMSECTVEILLETAMGVS 709
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 31.5 bits (68), Expect = 3.5
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 479 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 649
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 650 HDYMSECTVEILLETAMGVS 709
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 31.1 bits (67), Expect = 4.7
Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 479 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 649
++ + + ++ ++W+ R L++PTF LK + +V L++EA
Sbjct: 113 FMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172
Query: 650 HDYMSECTVEILLETAMGVS 709
D +++++ T+ GV+
Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,823,597
Number of Sequences: 237096
Number of extensions: 2210049
Number of successful extensions: 5209
Number of sequences better than 10.0: 119
Number of HSP's better than 10.0 without gapping: 4911
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5191
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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