Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0951
(625 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 107 2e-22
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 103 3e-21
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 3e-14
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 80 4e-14
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 80 5e-14
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 79 9e-14
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 79 1e-13
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 79 1e-13
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 78 1e-13
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 78 1e-13
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 78 2e-13
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 77 3e-13
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 77 3e-13
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 75 1e-12
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 6e-12
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 70 5e-11
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 69 7e-11
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 69 1e-10
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 68 2e-10
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 66 6e-10
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 65 1e-09
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 64 2e-09
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 63 5e-09
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 63 5e-09
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 61 2e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 60 4e-08
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 60 4e-08
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 60 4e-08
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 60 6e-08
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 60 6e-08
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 59 1e-07
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 58 1e-07
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 58 2e-07
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 55 1e-06
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 55 2e-06
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 54 2e-06
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 54 4e-06
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 53 6e-06
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 52 8e-06
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 52 1e-05
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 52 1e-05
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 50 3e-05
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 50 5e-05
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 46 7e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 43 0.005
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 43 0.005
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 41 0.021
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 41 0.021
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 36 0.60
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 0.79
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 34 3.2
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 33 4.2
UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolyti... 33 7.3
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 33 7.3
UniRef50_Q5RJR1 Cluster: Putative uncharacterized protein; n=2; ... 33 7.3
UniRef50_Q4QIZ6 Cluster: Putative uncharacterized protein; n=2; ... 32 9.7
UniRef50_A7ENK1 Cluster: Predicted protein; n=1; Sclerotinia scl... 32 9.7
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 107 bits (258), Expect = 2e-22
Identities = 67/131 (51%), Positives = 77/131 (58%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDARR 192
ALLSVSDKTGL+ AK L + GL L+ASGGTA A S GH E G +
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G L+ DM++ Y +I VVVCNLYPFV+TVS P VTV DAVE
Sbjct: 61 TLHPAVHGGI---LARKSPADTADMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQ 117
Query: 373 IDIGGVTLLRA 405
IDIGGVTLLRA
Sbjct: 118 IDIGGVTLLRA 128
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 103 bits (248), Expect = 3e-21
Identities = 63/134 (47%), Positives = 79/134 (58%), Gaps = 3/134 (2%)
Frame = +1
Query: 13 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTGD 183
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA + S G E G
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 184 ARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADA 363
++ +G L+ I DM R + +I VV CNLYPFV+TV+ P VTV +A
Sbjct: 64 RVKTLHPAVHAGI---LARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA 120
Query: 364 VENIDIGGVTLLRA 405
VE IDIGGVTLLRA
Sbjct: 121 VEQIDIGGVTLLRA 134
Score = 71.7 bits (168), Expect = 1e-11
Identities = 33/41 (80%), Positives = 38/41 (92%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ALR+AGL V+DVS++T PEMLGGRVKTLHPAVHAGILAR
Sbjct: 39 KALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILAR 79
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/50 (48%), Positives = 32/50 (64%)
Frame = +2
Query: 464 SXRNQXEQTXSDDFWTKQRLALKAFTHTSXYDLAISXYFRXXYSPGXAQL 613
S Q ++ T+++LALKAFTHT+ YD AIS YFR YS G +Q+
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQM 204
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 85.0 bits (201), Expect = 1e-15
Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRP--HSSRCVGHHESTGDAR 189
K A+LSVS+KTG++ AK+L++ +L ++GGT E S + H D R
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 190 -RSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G D + L ++ Q ++I +VV NLYPF QTV+ PDVT+ +A+
Sbjct: 62 VKTLHPAVHGGILADRNKPQHL--NELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAI 119
Query: 367 ENIDIGGVTLLRA 405
ENIDIGG T+LRA
Sbjct: 120 ENIDIGGPTMLRA 132
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 80.6 bits (190), Expect = 3e-14
Identities = 52/132 (39%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RRPHSSRCVGHHESTGDAR 189
L L SVSDKTGL A L G IASGGTA E + S E G
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 190 RSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVE 369
++ G L+ + + ++K + I +V+ NLYPF +T+S PD T +D +E
Sbjct: 63 KTLHPMIHGGI---LARDTKEDRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIE 119
Query: 370 NIDIGGVTLLRA 405
NIDIGGV LLRA
Sbjct: 120 NIDIGGVALLRA 131
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 80.2 bits (189), Expect = 4e-14
Identities = 51/130 (39%), Positives = 77/130 (59%), Gaps = 2/130 (1%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
ALLSVSDKTG++ A+ L + G++L+++GGTA ++ ++ + + TG
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQ---NALPVIEVSDYTGFPEMMDG 65
Query: 202 NFTSSGTCWDLSSIIRLCQED--MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENI 375
+ + R +D M++ E I +VV NLYPF TV+KPD T+ADAVENI
Sbjct: 66 RVKTLHPKVHGGILGRRGTDDAIMQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENI 125
Query: 376 DIGGVTLLRA 405
DIGG T++R+
Sbjct: 126 DIGGPTMVRS 135
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ L L V +VSD T PEM+ GRVKTLHP VH GIL R
Sbjct: 41 KLLAQNALPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILGR 81
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/32 (46%), Positives = 19/32 (59%)
Frame = +2
Query: 503 FWTKQRLALKAFTHTSXYDLAISXYFRXXYSP 598
F T+ LA+KAF HT+ YD I+ YF P
Sbjct: 168 FETRFDLAIKAFEHTAQYDSMIANYFGQLVKP 199
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/130 (37%), Positives = 76/130 (58%), Gaps = 2/130 (1%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
ALLSVSDK G++ A++LS+ G++L+++GGTA ++ + + TG
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDY---TGFPEMMDG 66
Query: 202 NFTSSGTCWDLSSIIRLCQED--MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENI 375
+ + R Q+D M + + I +VV NLYPF QTV++PD ++ DAVENI
Sbjct: 67 RVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENI 126
Query: 376 DIGGVTLLRA 405
DIGG T++R+
Sbjct: 127 DIGGPTMVRS 136
Score = 57.2 bits (132), Expect = 3e-07
Identities = 27/41 (65%), Positives = 30/41 (73%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
R L +AGL V +VSD T PEM+ GRVKTLHP VH GIL R
Sbjct: 42 RLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGR 82
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 79.0 bits (186), Expect = 9e-14
Identities = 50/130 (38%), Positives = 71/130 (54%), Gaps = 2/130 (1%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASER--RPHSSRCVGHHESTGDARRS 195
ALLSV +K+G++ +K LS G LI++GGTA + + V + D R
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 196 GENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENI 375
+ G + Q D+ + + IS+VV NLYPFV+TVSK T+ +A+ENI
Sbjct: 63 TLHPKIHGGLLARPELAHH-QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENI 121
Query: 376 DIGGVTLLRA 405
DIGG TL+RA
Sbjct: 122 DIGGHTLIRA 131
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/41 (63%), Positives = 32/41 (78%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
++L + GL VQ VSD+T PEML GRVKTLHP +H G+LAR
Sbjct: 35 KSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLAR 75
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/133 (36%), Positives = 74/133 (55%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDA 186
K ALLSVSDKTG++ A+ L G+++I++GGTA A S G+ E G
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G S ++ E+ ++ +I ++ NLYPF TVS+ +V + +A+
Sbjct: 63 VKTLHPRIHGGLLCLRESKEQM--EEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAI 120
Query: 367 ENIDIGGVTLLRA 405
ENIDIGG TLLR+
Sbjct: 121 ENIDIGGPTLLRS 133
Score = 56.0 bits (129), Expect = 7e-07
Identities = 23/39 (58%), Positives = 31/39 (79%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 235
+ LR+A + V DVS++T PEM+GGRVKTLHP +H G+L
Sbjct: 37 KILRDADIEVTDVSEVTGYPEMMGGRVKTLHPRIHGGLL 75
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 78.6 bits (185), Expect = 1e-13
Identities = 56/136 (41%), Positives = 76/136 (55%), Gaps = 6/136 (4%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERRPHSSRC---VGHHESTGD 183
+LALLSVSDK+G++ LA+ L +E LI+SGGTA E ++ G E G
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 184 ARRSGENFTSSGTCW--DLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVA 357
++ G DL S Q D++ + +VV NLYPF QT++KP VTVA
Sbjct: 63 RVKTLHPRIHGGILARRDLPSD----QADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVA 118
Query: 358 DAVENIDIGGVTLLRA 405
+AVE IDIGG ++RA
Sbjct: 119 EAVEQIDIGGPAMIRA 134
Score = 60.5 bits (140), Expect = 3e-08
Identities = 27/41 (65%), Positives = 32/41 (78%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ L+ AG+ V VSD T APE+LGGRVKTLHP +H GILAR
Sbjct: 38 KTLKEAGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILAR 78
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 78.2 bits (184), Expect = 1e-13
Identities = 58/134 (43%), Positives = 73/134 (54%), Gaps = 5/134 (3%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRS 195
LALLSVSDKTGL+ LA+SL E G QL++SGGTA SE + H TG
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAH---TGAPEIL 73
Query: 196 GENFTSSGTCWDLSSIIRL-CQED---MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADA 363
G + + RL C ED ++ I +VV N YPF QTV++ V++ +A
Sbjct: 74 GGRVKTLHPRIHGGILARLECSEDRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEA 133
Query: 364 VENIDIGGVTLLRA 405
E IDIGG TL RA
Sbjct: 134 FEQIDIGGPTLARA 147
Score = 59.3 bits (137), Expect = 7e-08
Identities = 29/45 (64%), Positives = 33/45 (73%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS 253
+AL AG+ V VS T APE+LGGRVKTLHP +H GILARL S
Sbjct: 51 KALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLECS 95
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 78.2 bits (184), Expect = 1e-13
Identities = 48/133 (36%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSS---RCVGHHESTGDA 186
K AL+SVSDKT ++ AK L E G +++++GGT +E + G E
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G S+ L Q M+ I +V NLYPF +TV KPDV+ D +
Sbjct: 63 VKTLHPMIHGGLLGKRSNHEHLSQ--MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDII 120
Query: 367 ENIDIGGVTLLRA 405
ENIDIGG ++LR+
Sbjct: 121 ENIDIGGPSMLRS 133
Score = 32.3 bits (70), Expect = 9.7
Identities = 13/29 (44%), Positives = 19/29 (65%)
Frame = +2
Query: 494 SDDFWTKQRLALKAFTHTSXYDLAISXYF 580
+D + +Q+LA K F HT+ YD I+ YF
Sbjct: 161 TDTYEFRQQLAAKVFRHTASYDAMIANYF 189
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/134 (39%), Positives = 73/134 (54%), Gaps = 4/134 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDAR-R 192
K AL+SVSDKT L+ K L+E G+++I++GGT E + +G E TG
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQE---NGVDVIGISEVTGFPEIM 60
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKR---QKYEMISVVVCNLYPFVQTVSKPDVTVADA 363
G T +R +E M + + I +VV NLYPF +T+SK DVT +A
Sbjct: 61 DGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLVVVNLYPFKETISKEDVTYEEA 120
Query: 364 VENIDIGGVTLLRA 405
+ENIDIGG +LRA
Sbjct: 121 IENIDIGGPGMLRA 134
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/133 (42%), Positives = 74/133 (55%), Gaps = 4/133 (3%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERR-PHS--SRCVGHHESTGDA 186
LALLSVSDKTGL+ LA++L E G QL++SGGTA SE P + S G E G
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G L R + D++ I +VV N YPF QTV++ V++ +A
Sbjct: 69 VKTLHPRIHGGILARLER--REDRADLEALGIPPIQLVVVNFYPFEQTVARAGVSLEEAF 126
Query: 367 ENIDIGGVTLLRA 405
E IDIGG TL RA
Sbjct: 127 EQIDIGGPTLARA 139
Score = 60.5 bits (140), Expect = 3e-08
Identities = 28/42 (66%), Positives = 33/42 (78%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL 244
+AL AG+ V VS+ T APE+LGGRVKTLHP +H GILARL
Sbjct: 43 KALSEAGIPVTPVSEHTGAPEILGGRVKTLHPRIHGGILARL 84
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 77.0 bits (181), Expect = 3e-13
Identities = 47/133 (35%), Positives = 77/133 (57%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRC---VGHHESTGDA 186
K AL+SVSDK+GL+ AK L++ G+++I++GGT + + G E
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G +S+ ++ M+ K I +VV NLYPF++TVSKP+V + +A+
Sbjct: 65 VKTLHPKVHGGLLGVISNPAH--KQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAI 122
Query: 367 ENIDIGGVTLLRA 405
ENIDIGG +++R+
Sbjct: 123 ENIDIGGPSMIRS 135
Score = 49.6 bits (113), Expect = 6e-05
Identities = 22/48 (45%), Positives = 31/48 (64%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSARK 262
+ L++ G+ + D T PE+L GRVKTLHP VH G+L +S+ A K
Sbjct: 39 KLLKDNGIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHK 86
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 74.9 bits (176), Expect = 1e-12
Identities = 59/132 (44%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
ALLSVSDKTGLL LAK+L+ ++LIASGGTA +E + V G+A +G
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVT-AVETLSGKGEA-FNGR 64
Query: 202 NFTSSGTCWDLSSIIRLCQEDMKRQKYEM----ISVVVCNLYPFVQTVSKPDVTVADAVE 369
T S S + R E+ RQ E+ I +VV NLYPF T+ K + +E
Sbjct: 65 MKTISFEIAS-SLLFRRQDENDVRQAAELGIEPIDLVVVNLYPFHATLQK-QAGFEECIE 122
Query: 370 NIDIGGVTLLRA 405
NIDIGG TLLRA
Sbjct: 123 NIDIGGPTLLRA 134
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 72.9 bits (171), Expect = 6e-12
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 6/134 (4%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDARR 192
AL+SVSDK G+L A+ L+ G++L+++GGTA A S G E +
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 193 SGENFTSSGTCW--DLSSII-RLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADA 363
+ G DL+ + + D+ R I +VV NLYPF TV++PD T+ DA
Sbjct: 66 TLHPKVHGGILARRDLAEHMDTIAAHDISR-----IDLVVVNLYPFQATVARPDCTLEDA 120
Query: 364 VENIDIGGVTLLRA 405
+ENIDIGG T++RA
Sbjct: 121 IENIDIGGPTMVRA 134
Score = 59.7 bits (138), Expect = 6e-08
Identities = 29/39 (74%), Positives = 31/39 (79%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
LR+AGL V DVS+ T PEML GRVKTLHP VH GILAR
Sbjct: 40 LRDAGLPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILAR 78
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 69.7 bits (163), Expect = 5e-11
Identities = 52/135 (38%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Frame = +1
Query: 10 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTG 180
N K AL+SVSDK GL+ AK+L + G+++I++GGTA S+ S G E G
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 181 DARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVAD 360
++ G DL + +D++ E I +VV NLYPF V K
Sbjct: 62 GRVKTLHPKIFGGILADLGDKSHV--KDLRDNFIEPIDLVVVNLYPF-DEVQKKTRDEDV 118
Query: 361 AVENIDIGGVTLLRA 405
+ENIDIGGV LLRA
Sbjct: 119 LIENIDIGGVALLRA 133
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/46 (56%), Positives = 34/46 (73%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSA 256
+ L +AG+ V+ VSD+T PE+LGGRVKTLHP + GILA L D +
Sbjct: 38 KLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKS 83
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 69.3 bits (162), Expect = 7e-11
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTGDARR 192
ALLSVSDKTGL+ LA++L ++L+++GGTAT E + G E +
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G L + M + I +++ NLYPF Q +K D T+ADAV+
Sbjct: 71 TLHPMVHGG----LLGRAGIDDAVMAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDT 126
Query: 373 IDIGGVTLLRA 405
IDIGG +LR+
Sbjct: 127 IDIGGPAMLRS 137
Score = 60.1 bits (139), Expect = 4e-08
Identities = 26/39 (66%), Positives = 31/39 (79%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+R AGL VQDV+D+T PEM+ GRVKTLHP VH G+L R
Sbjct: 45 IREAGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLGR 83
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 68.5 bits (160), Expect = 1e-10
Identities = 46/135 (34%), Positives = 72/135 (53%), Gaps = 5/135 (3%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHS---SRCVGHHESTGDA 186
K AL+SVSDK G++ A+ L++ G ++I++GGT + + G E
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 187 RRSGENFTSSGTCW--DLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVAD 360
++ G DL S ++ + + +I +VV NLYPF +T+ +PDVT
Sbjct: 63 VKTLHPKIHGGLLARRDLDSHLQAAND----HEIGLIDLVVVNLYPFKETILRPDVTYDL 118
Query: 361 AVENIDIGGVTLLRA 405
AVENIDIGG ++LR+
Sbjct: 119 AVENIDIGGPSMLRS 133
Score = 53.6 bits (123), Expect = 4e-06
Identities = 23/40 (57%), Positives = 29/40 (72%)
Frame = +2
Query: 122 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
AL AG+T + D+T PEM+ GRVKTLHP +H G+LAR
Sbjct: 38 ALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLAR 77
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +2
Query: 509 TKQRLALKAFTHTSXYDLAISXYF 580
T+QRLA K F HT+ YD I+ YF
Sbjct: 167 TRQRLAAKVFRHTAAYDALIADYF 190
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/132 (33%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRS 195
K AL+S +DK GL+ L CG+++IA+GGTA + H + TG
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQ---HQLPVIDVFTYTGFPEIM 68
Query: 196 GENFTSSGTCWDLSSIIR--LCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVE 369
+ + R + ++ + + + I ++V NLYPFVQTVS + ++ AVE
Sbjct: 69 DGRVKTLHPKIHAGLLARRGIDEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVE 128
Query: 370 NIDIGGVTLLRA 405
IDIGG ++LRA
Sbjct: 129 QIDIGGPSMLRA 140
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/39 (56%), Positives = 27/39 (69%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
L+ L V DV T PE++ GRVKTLHP +HAG+LAR
Sbjct: 48 LKQHQLPVIDVFTYTGFPEIMDGRVKTLHPKIHAGLLAR 86
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 66.1 bits (154), Expect = 6e-10
Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RRPHSSRCVGHHESTGDARR 192
ALLSVSDKTGL+ A+SL+ G++LI++GGTA ++ + S G E D R
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMM-DGRV 69
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G + E MK I ++V NLYPF TV + +D +EN
Sbjct: 70 KTLHPKVHGGLLAIRGNDEHA-EAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIEN 127
Query: 373 IDIGGVTLLRA 405
IDIGG ++RA
Sbjct: 128 IDIGGPAMIRA 138
Score = 59.7 bits (138), Expect = 6e-08
Identities = 26/40 (65%), Positives = 33/40 (82%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
+A+ +AGL V+DVSD+T PEM+ GRVKTLHP VH G+LA
Sbjct: 43 KAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLA 82
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 65.7 bits (153), Expect = 9e-10
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDA 186
K AL+SV DKTGL LA++L E G++++++G TA A G E
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ F SG D +E + + + +VVCNLYPF TV+ + + V
Sbjct: 77 VKTLHPFIHSGILADQRKAAH--REQIAQLGIQAFDLVVCNLYPFQDTVAS-GASFDECV 133
Query: 367 ENIDIGGVTLLRA 405
E IDIGG +++RA
Sbjct: 134 EQIDIGGPSMVRA 146
Score = 50.4 bits (115), Expect = 3e-05
Identities = 23/43 (53%), Positives = 30/43 (69%)
Frame = +2
Query: 134 AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSARK 262
AG+ V V D+T PE+L GRVKTLHP +H+GILA +A +
Sbjct: 56 AGVAVTPVDDVTGFPEVLEGRVKTLHPFIHSGILADQRKAAHR 98
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 64.9 bits (151), Expect = 1e-09
Identities = 43/133 (32%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHS---SRCVGHHESTGDA 186
+ AL+SVSDKTG+ SLAK+L + ++LI + GT E+ S S + H E
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G + +I + K + I +V+ N YPF + V K ++ + + +
Sbjct: 69 VKTLHPKIHGGILSNNKNI-----NENKNLNIKKIDMVITNFYPFKKKVKKENIKIENII 123
Query: 367 ENIDIGGVTLLRA 405
+NIDIGGV L R+
Sbjct: 124 DNIDIGGVALARS 136
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/131 (36%), Positives = 65/131 (49%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDARR 192
AL+SV DKTG+L LAK L G ++++SGGT T A S G E G +
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G + + E++K E I +VV NLYPF + + K + VE
Sbjct: 63 TLHPAIHGGILF--REDVEKDLEEIKENSIEPIDIVVVNLYPFEKKM-KELKDIDALVEF 119
Query: 373 IDIGGVTLLRA 405
IDIGG TL+RA
Sbjct: 120 IDIGGPTLVRA 130
Score = 54.4 bits (125), Expect = 2e-06
Identities = 24/39 (61%), Positives = 31/39 (79%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
L+NAG+ +VS++T E+LGGRVKTLHPA+H GIL R
Sbjct: 37 LKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFR 75
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 63.3 bits (147), Expect = 5e-09
Identities = 28/40 (70%), Positives = 34/40 (85%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
RAL AGL V++VS++TR PEM+ GRVKTLHPAVH G+LA
Sbjct: 92 RALTEAGLAVREVSELTRFPEMMDGRVKTLHPAVHGGLLA 131
Score = 55.2 bits (127), Expect = 1e-06
Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASER--RPHSSRCVGHHESTGDARRS 195
ALLSVSDKTGL A +LS+ G++L+++GGT +E + D R
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 196 GENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENI 375
+ G + Q + I ++V NLYPF +T+ K D VENI
Sbjct: 120 TLHPAVHGGLLAVRDNPE-HQAALAAHGIGAIDLLVVNLYPFEETL-KAGKAYDDCVENI 177
Query: 376 DIGGVTLLRA 405
D+GG ++RA
Sbjct: 178 DVGGPAMIRA 187
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 63.3 bits (147), Expect = 5e-09
Identities = 48/133 (36%), Positives = 71/133 (53%), Gaps = 5/133 (3%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTG-----DA 186
AL+SVSDK+ L LA+ L ++++++GGT SE V E TG D
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSEL---GVAVVKVSEFTGAPEILDG 73
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
R + G L + Q +++ I +V+ NLYPF +T++KP + ADA+
Sbjct: 74 RVKTLHPKIHGGILALPTEAH--QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAI 131
Query: 367 ENIDIGGVTLLRA 405
ENIDIGG T++RA
Sbjct: 132 ENIDIGGPTMVRA 144
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/40 (62%), Positives = 29/40 (72%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
RAL G+ V VS+ T APE+L GRVKTLHP +H GILA
Sbjct: 49 RALSELGVAVVKVSEFTGAPEILDGRVKTLHPKIHGGILA 88
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/131 (34%), Positives = 62/131 (47%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA---TGASERRPHSSRCVGHHESTGDARR 192
AL+SV DKTGL LAK L E G++++++G TA A G E +
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G D + E + + E +VV NLYPFV+TV K D VE
Sbjct: 74 TLHPRVHGGILADRR--VPAHMETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQ 130
Query: 373 IDIGGVTLLRA 405
IDIGG ++R+
Sbjct: 131 IDIGGPAMVRS 141
Score = 55.6 bits (128), Expect = 9e-07
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = +2
Query: 134 AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
AG+ VQ+V ++T +PEML GRVKTLHP VH GILA
Sbjct: 51 AGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILA 85
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +2
Query: 500 DFWTKQRLALKAFTHTSXYDLAISXY 577
D T+QRLA KAF HT+ YD A++ +
Sbjct: 171 DLKTRQRLAAKAFAHTASYDTAVATW 196
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHS---SRCVGHHESTGDARR 192
AL+SVSDKTG++ A L ++++++GGTA E S G E +
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G S + M+ E I +VV +LYPF +T+ V++A+A+E
Sbjct: 75 TLHPKIHGGLLGVRDSPSH--ESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQ 132
Query: 373 IDIGGVTLLRA 405
IDIGG ++R+
Sbjct: 133 IDIGGPAMIRS 143
Score = 58.4 bits (135), Expect = 1e-07
Identities = 24/39 (61%), Positives = 31/39 (79%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 235
+ LR AG+ V+DVSD+T PEM+ GRVKTLHP +H G+L
Sbjct: 47 KTLREAGIEVRDVSDVTGFPEMMDGRVKTLHPKIHGGLL 85
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 60.1 bits (139), Expect = 4e-08
Identities = 49/135 (36%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Frame = +1
Query: 25 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATGASERRPHSSRCVGHHES--TGDARR 192
L+SVSDKTGL L + + ++GGT E +++ V S TG
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 193 SGENFTSSGTCWDLSSIIRLCQE----DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVAD 360
G + L + E DMKR I +VV NLYPF QTV++PDVT
Sbjct: 79 QGGLVKTLDFKIYLGLLTETYNESHARDMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQ 138
Query: 361 AVENIDIGGVTLLRA 405
A NIDIGG ++RA
Sbjct: 139 ARGNIDIGGPCMVRA 153
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 60.1 bits (139), Expect = 4e-08
Identities = 27/39 (69%), Positives = 31/39 (79%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
L AG+ V+ VSD+T PEML GRVKTLHPA+H GILAR
Sbjct: 39 LSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILAR 77
Score = 55.6 bits (128), Expect = 9e-07
Identities = 48/135 (35%), Positives = 67/135 (49%), Gaps = 5/135 (3%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT---ATGASERRPHSSRCVGHHESTGDA 186
K AL+SVSDKTG++ A L + G +L+++GGT +GA S G E D
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEML-DG 61
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSK--PDVTVAD 360
R + G L Q + Q I +V NLYPF +TV++ PD V
Sbjct: 62 RVKTLHPAIHGGILARREAGHLGQ--LAAQDIGTIDLVCVNLYPFRETVARGAPDPEV-- 117
Query: 361 AVENIDIGGVTLLRA 405
+ENIDIGG ++R+
Sbjct: 118 -IENIDIGGPAMIRS 131
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 60.1 bits (139), Expect = 4e-08
Identities = 43/131 (32%), Positives = 68/131 (51%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTGDARR 192
A++SV K G+ LAK+L E G +++++GGTA E+ S G E +
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G + + +E++++ + I VVV NLYPF + + K +T D +E
Sbjct: 63 TLHPVVHGGILF--RDWVEKDKEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEF 119
Query: 373 IDIGGVTLLRA 405
IDIGG TL+RA
Sbjct: 120 IDIGGPTLIRA 130
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/39 (64%), Positives = 31/39 (79%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
LR G++V++VS+IT PE+L GRVKTLHP VH GIL R
Sbjct: 37 LREKGISVKEVSEITGFPEILEGRVKTLHPVVHGGILFR 75
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 59.7 bits (138), Expect = 6e-08
Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 3/139 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDA 186
K AL+SVSDK+GL LA++L+ ++++++G TA G S S G E
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ + D +S + Q +++ + +VV NLYPF + + +D +
Sbjct: 68 VKTLHPKIHAPILADTTSQMHRAQ--LQQLGVDAFDLVVVNLYPFFEISKNSEAEFSDVI 125
Query: 367 ENIDIGGVTLLRAXPRTTT 423
E IDIGG L+RA + T
Sbjct: 126 EQIDIGGSALIRAAAKNHT 144
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
+R + V+DVS++T E+L GRVKTLHP +HA ILA
Sbjct: 44 IRGVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILA 81
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 59.7 bits (138), Expect = 6e-08
Identities = 27/40 (67%), Positives = 32/40 (80%)
Frame = +2
Query: 122 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
AL AG++V V ++TR PEML GRVKTLHP+VH GILAR
Sbjct: 124 ALEGAGVSVTKVEELTRFPEMLDGRVKTLHPSVHGGILAR 163
Score = 57.2 bits (132), Expect = 3e-07
Identities = 42/137 (30%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +1
Query: 7 SNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHEST 177
S K AL+S+SDKT L L L E G ++++GGT++ GA E
Sbjct: 86 SGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEML 145
Query: 178 GDARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPD-VTV 354
++ G + E +++ + VVV NLYPF VS ++
Sbjct: 146 DGRVKTLHPSVHGGILARRDQEHHM--EALEKHEIGTFDVVVVNLYPFYAKVSSSSGISF 203
Query: 355 ADAVENIDIGGVTLLRA 405
D +ENIDIGG ++RA
Sbjct: 204 EDGIENIDIGGPAMIRA 220
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 58.8 bits (136), Expect = 1e-07
Identities = 25/41 (60%), Positives = 32/41 (78%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ALR AG+ +DVS+ T+ PEM+ GRVKTLHP VH G+L R
Sbjct: 36 KALREAGIPAKDVSEYTQFPEMMDGRVKTLHPKVHGGLLGR 76
Score = 57.6 bits (133), Expect = 2e-07
Identities = 41/129 (31%), Positives = 65/129 (50%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSG 198
LALLSV DKTG+L LA++L + +++SGGTA E ++ V + +
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALRE-AGIPAKDVSEYTQFPEMMDGR 61
Query: 199 ENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENID 378
L + + MK E I ++ NLYPF + +SK ++ + + +E ID
Sbjct: 62 VKTLHPKVHGGLLGRRGIDDDVMKAHFIEPIDILCVNLYPF-EEMSKKNLPLEELIEFID 120
Query: 379 IGGVTLLRA 405
IGG ++RA
Sbjct: 121 IGGPAMIRA 129
Score = 32.3 bits (70), Expect = 9.7
Identities = 15/22 (68%), Positives = 16/22 (72%)
Frame = +2
Query: 512 KQRLALKAFTHTSXYDLAISXY 577
K RLA KAFT T+ YD AIS Y
Sbjct: 163 KLRLATKAFTRTAAYDAAISNY 184
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 58.4 bits (135), Expect = 1e-07
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTGDA 186
K AL+SVSDK L SL + L++ ++LI+SGGT + + S G E G
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ +G + + +++K +Y+ I +V+ N YPF +T+ + + +
Sbjct: 72 VKTLHPKIHAGILSKRND--KSHTKELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKII 128
Query: 367 ENIDIGGVTLLRA 405
ENID+GG T++RA
Sbjct: 129 ENIDVGGPTMVRA 141
Score = 54.0 bits (124), Expect = 3e-06
Identities = 22/36 (61%), Positives = 31/36 (86%)
Frame = +2
Query: 149 QDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSA 256
Q+VS+ T +PE+LGGRVKTLHP +HAGIL++ +D +
Sbjct: 56 QEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKS 91
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 57.6 bits (133), Expect = 2e-07
Identities = 48/136 (35%), Positives = 67/136 (49%), Gaps = 6/136 (4%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERR---PHSSRCVGHHESTGDA 186
K AL+SV DK G+L LAK L + +++I+SGGT E S E
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMK---RQKYEMISVVVCNLYPFVQTVSKPDVTVA 357
++ +G IR +E MK ++ I VV NLYPF + V + D++
Sbjct: 63 VKTLHPLVHAGIL-----AIRDNKEHMKTLEEREINTIDYVVVNLYPFFEKV-REDLSFE 116
Query: 358 DAVENIDIGGVTLLRA 405
+ VE IDIGG T+LRA
Sbjct: 117 EKVEFIDIGGPTMLRA 132
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/38 (63%), Positives = 30/38 (78%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
L+ + V+++S+IT PEML GRVKTLHP VHAGILA
Sbjct: 39 LKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILA 76
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/133 (31%), Positives = 66/133 (49%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERRPHSSRCVGHHESTGDA 186
K ALLSV DKTG++ LA++L + +++SGGT T GA SR G E
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 187 RRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAV 366
++ G L ++ M + I ++V NLYPF + +S+ + + +
Sbjct: 92 VKTLHPKVHGG----LLGRRQIDDAIMAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLI 146
Query: 367 ENIDIGGVTLLRA 405
E ID+GG ++RA
Sbjct: 147 EYIDVGGPAMIRA 159
Score = 50.0 bits (114), Expect = 5e-05
Identities = 23/40 (57%), Positives = 27/40 (67%)
Frame = +2
Query: 122 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
AL AG+ +VS T PEM+ GRVKTLHP VH G+L R
Sbjct: 67 ALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLGR 106
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/40 (62%), Positives = 29/40 (72%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA 238
R L AGL V VS +T PE++GGRVKTLHP +H GILA
Sbjct: 94 RTLTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILA 133
Score = 52.8 bits (121), Expect = 6e-06
Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 3/131 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGG---TATGASERRPHSSRCVGHHESTGDARR 192
ALLSV+DK+GL+ A L++ G++L+++GG T T A S+ G E G +
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ G D + L +K ++ NLY F ++ + + AVE
Sbjct: 122 TLHPHIHGGILADKDNPEHLA--TLKELGIRTFDLICVNLYNFADAAAR-GLDLRGAVEE 178
Query: 373 IDIGGVTLLRA 405
+DIGG +LRA
Sbjct: 179 VDIGGPCMLRA 189
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 54.4 bits (125), Expect = 2e-06
Identities = 23/44 (52%), Positives = 32/44 (72%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD 250
+ L+ G+ V +VSD T++PE+ GRVKTLHP +H GIL + SD
Sbjct: 35 KLLKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSD 78
Score = 46.0 bits (104), Expect = 7e-04
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 10/138 (7%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
ALLSVSDK G++ K L G +++++GGT E + + + D +S E
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKE---NGIKVI----EVSDFTKSPE 55
Query: 202 NFTSSGTCWDLSSII-------RLCQEDMKRQK-YEMISV-VVC-NLYPFVQTVSKPDVT 351
F G L I R + +K+ K E++ + +VC NLYPF +T D
Sbjct: 56 LF--EGRVKTLHPKIHGGILHKRSDENHIKQAKENEILGIDLVCVNLYPFKKTTIMSD-D 112
Query: 352 VADAVENIDIGGVTLLRA 405
+ +ENIDIGG ++R+
Sbjct: 113 FDEIIENIDIGGPAMIRS 130
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/44 (54%), Positives = 32/44 (72%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD 250
+ L G+ V +VSD+T PE L GRVKTLHP +HAGILA +++
Sbjct: 43 KKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTN 86
Score = 50.4 bits (115), Expect = 3e-05
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RRPHSSRCVGHHESTGDARR 192
AL+SV K G+ LA++ + G +++++G TA +E + S G E +
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 193 SGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
+ + +G D+++ Q ++ + +VV NLYPF TV + AD +E
Sbjct: 71 TLHPYIHAGILADMTNPEHAKQ--LEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIEK 127
Query: 373 IDIGGVTLLR 402
IDIGG +++R
Sbjct: 128 IDIGGPSMVR 137
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 52.8 bits (121), Expect = 6e-06
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRS 195
K L+SVSD + ++ +KSL ++L A+ GTA + +++ + + +
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNY--TNFPEIMN 65
Query: 196 GENFTSSGTCWDLSSIIRLCQEDMKR-QKYEMI--SVVVCNLYPFVQTVSKPDVTVADAV 366
G T + +SI+ + D K +KY +I +VV N YPF + + ++ + D +
Sbjct: 66 GRIKTLHHKIY--ASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDII 123
Query: 367 ENIDIGGVTLLRA 405
E+IDIGG ++RA
Sbjct: 124 EHIDIGGPAIVRA 136
Score = 38.7 bits (86), Expect = 0.11
Identities = 15/39 (38%), Positives = 26/39 (66%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
L+ + D+++ T PE++ GR+KTLH ++A ILA+
Sbjct: 44 LKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQ 82
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 52.4 bits (120), Expect = 8e-06
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRS 195
K AL+SV K GL + L E G++ +++GGT E + + V +T +
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFI-ESLGYPCKAV-EDLTTYPSILG 65
Query: 196 GENFTSSGTCWDLSSIIRLCQEDMKR-QKYEM--ISVVVCNLYPFVQTVSKPDVTVADAV 366
G T + R ++D+++ +KYE+ I +V+ +LYPF TV+ + AD +
Sbjct: 66 GRVKTLHPKIFGGILCRRDLEQDIQQIEKYEIPEIDLVIVDLYPFEATVAS-GASEADII 124
Query: 367 ENIDIGGVTLLRA 405
E IDIGG++L+RA
Sbjct: 125 EKIDIGGISLIRA 137
Score = 44.4 bits (100), Expect = 0.002
Identities = 19/39 (48%), Positives = 25/39 (64%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ + G + V D+T P +LGGRVKTLHP + GIL R
Sbjct: 44 IESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCR 82
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 51.6 bits (118), Expect = 1e-05
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 3/135 (2%)
Frame = +1
Query: 10 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRC---VGHHESTG 180
N K A++SV DKT L LA L G+++I + GT E+ + + +G E G
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 181 DARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVAD 360
+S + + G S + +EDM + I +VV N +P + ++K
Sbjct: 62 GRVKSIDPKLAGGIL--AKSNDKKHEEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEET 118
Query: 361 AVENIDIGGVTLLRA 405
+ENIDIGG +LLRA
Sbjct: 119 LLENIDIGGYSLLRA 133
Score = 38.3 bits (85), Expect = 0.15
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD 250
L+ G+ ++D PE+LGGRVK++ P + GILA+ +D
Sbjct: 40 LQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSND 81
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 51.6 bits (118), Expect = 1e-05
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Frame = +1
Query: 25 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTG-DARRSGE 201
L+SVSD +GL L + L+ + A+ GT S+ + R + TG D +G
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRI---SDITGFDDLLNGR 57
Query: 202 NFTSSGTCWD--LSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENI 375
T + LS + D+KR Y +V+CNLY F + K ++ D +ENI
Sbjct: 58 VKTLHPAVFSGILSRRDEQSEADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENI 114
Query: 376 DIGGVTLLRA 405
DIGG++L+RA
Sbjct: 115 DIGGLSLIRA 124
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/44 (47%), Positives = 32/44 (72%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSA 256
L ++G+ + +SDIT ++L GRVKTLHPAV +GIL+R + +
Sbjct: 34 LSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRDEQS 77
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 50.4 bits (115), Expect = 3e-05
Identities = 23/39 (58%), Positives = 29/39 (74%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
L NAGLTV +SD T PE++ G+VKTLH + AGIL+R
Sbjct: 44 LTNAGLTVNKISDYTNFPEIMNGQVKTLHHKICAGILSR 82
Score = 48.4 bits (110), Expect = 1e-04
Identities = 34/128 (26%), Positives = 60/128 (46%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
AL+SV DK+ LL +KSLS G++L+++ GTA + ++ + + + +
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNK-ISDYTNFPEIMNGQV 68
Query: 202 NFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDI 381
C + S L + + + + I +V+ N YPF + +E IDI
Sbjct: 69 KTLHHKICAGILSRKNLDESIIHKYGIQPIDMVIVNFYPFHLILQNKQHDSEKILEYIDI 128
Query: 382 GGVTLLRA 405
GG ++RA
Sbjct: 129 GGPNMVRA 136
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/39 (56%), Positives = 27/39 (69%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
+ + G + V D+TR P MLGGRVKTLHP + GILAR
Sbjct: 45 ITSLGYACRAVDDLTRYPSMLGGRVKTLHPMIFGGILAR 83
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 4/131 (3%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRCVGHHESTGDARRSGE 201
AL+SV K GL + L+ G++ +++GGT + ++ R V + T G
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLG-YACRAVD--DLTRYPSMLGG 67
Query: 202 NFTSSGTCWDLSSIIRLCQEDMKRQKYE----MISVVVCNLYPFVQTVSKPDVTVADAVE 369
+ + R E R+ E +I +V+ +LYPF TV+ + D +E
Sbjct: 68 RVKTLHPMIFGGILARRGHESDVREVGEYGLPLIDLVIVDLYPFEATVAS-GASEEDIIE 126
Query: 370 NIDIGGVTLLR 402
IDIGG++L+R
Sbjct: 127 KIDIGGISLIR 137
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/41 (56%), Positives = 29/41 (70%)
Frame = +2
Query: 119 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
R LR+ G+TV VSD+ P +LGGRVKTL ++ GILAR
Sbjct: 35 RLLRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILAR 75
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -2
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTD 301
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 43.2 bits (97), Expect = 0.005
Identities = 20/37 (54%), Positives = 25/37 (67%)
Frame = +2
Query: 125 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 235
L++ G+ DVS IT +LGG VKTLHP + AGIL
Sbjct: 38 LKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGIL 74
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = -2
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHHAYHLVLLTFHV 262
A+ G AAD+DVLD + HG V R ERV+V HH L + H+
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHHVDGLDAVLLHL 458
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 41.1 bits (92), Expect = 0.021
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +2
Query: 122 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
AL NA ++ V +T P++L G VKTLHP + GIL R
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 41.1 bits (92), Expect = 0.021
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +2
Query: 122 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 241
AL NA ++ V +T P++L G VKTLHP + GIL R
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPR 96
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 36.3 bits (80), Expect = 0.60
Identities = 22/36 (61%), Positives = 23/36 (63%)
Frame = -2
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH 295
AQ G AADVDVLD V L +RL ERVQV HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 0.79
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +2
Query: 182 MLGGRVKTLHPAVHAGILAR 241
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 33.9 bits (74), Expect = 3.2
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +1
Query: 157 VGHHESTGDARRSGEN-FTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTV 333
VG E T +++ + F +G+CWD S + R Q+ K+ E SV V N + V
Sbjct: 222 VGDWEVTAESQEPNKTCFVRAGSCWDSSPLHREVQQ-RKQVNKENRSVKVGNQHSLGVPV 280
Query: 334 SKPDV 348
SKP +
Sbjct: 281 SKPSI 285
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 33.5 bits (73), Expect = 4.2
Identities = 42/129 (32%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Frame = -2
Query: 399 QEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH--AYHLVLLTFHVFLAESDNRAKIP 226
Q G AADVDVLDRV V L ERVQV VL + A + +A +
Sbjct: 423 QHGRAADVDVLDRVGQAAVGLGGDRLERVQVQHQQVDGTDAVLGHDRIIQARTAQQAAMH 482
Query: 225 ACTAGCKVFTRPPSISGALVMSDTS*TVRPAFRSA--RGGTATGNQLQATFRQALC*RE* 52
G P++ D + R A GG A G QL A RQ +
Sbjct: 483 HRVQGL-----DPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQ 537
Query: 51 TRLV*NAEK 25
T LV N E+
Sbjct: 538 TGLVGNGEE 546
>UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolytica
HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
Length = 672
Score = 32.7 bits (71), Expect = 7.3
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +1
Query: 145 SSRCVGHHESTG-DARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPF 321
SS GHH+ G +++ E + W + +RL ++ K ++ ++I++V+ PF
Sbjct: 580 SSFLQGHHKKLGITEQKTSEKIKEDRSAWGEAVCVRLMKKMKKCRELDLINMVIKEKAPF 639
Query: 322 VQT 330
+ T
Sbjct: 640 IPT 642
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 32.7 bits (71), Expect = 7.3
Identities = 17/45 (37%), Positives = 24/45 (53%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERRPHSSRC 156
ALLSVSDKTGL A +L G++L+++ S +C
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGLRSGKC 48
>UniRef50_Q5RJR1 Cluster: Putative uncharacterized protein; n=2;
Rattus norvegicus|Rep: Putative uncharacterized protein
- Rattus norvegicus (Rat)
Length = 279
Score = 32.7 bits (71), Expect = 7.3
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Frame = +1
Query: 112 TATGASERRPHSSR-CVGHHESTGDARRSGENFTSSGTCWDLS 237
T T A+E++ R C HH ST A SG + + CWD++
Sbjct: 155 TRTTATEKQSKERRGCWDHHSSTCSASTSGGSPLPTEACWDMA 197
>UniRef50_Q4QIZ6 Cluster: Putative uncharacterized protein; n=2;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 3258
Score = 32.3 bits (70), Expect = 9.7
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Frame = -2
Query: 306 TDHHAYHL---VLLTFHVFLAESDNRAKIPACTAGCKVFTRPPSISGALVMSDTS*TVRP 136
T HH++ L LL F+ L + A A TA S S A M D+ +
Sbjct: 1543 TSHHSFELFEWALLPFYTKLEARQHDANAAATTADKAAAAPSQSHSTAAPMMDSFLCLED 1602
Query: 135 AFRSARGGTATGNQLQAT 82
A+R G +TG+ AT
Sbjct: 1603 AYRDCAAGLSTGSPSGAT 1620
>UniRef50_A7ENK1 Cluster: Predicted protein; n=1; Sclerotinia
sclerotiorum 1980|Rep: Predicted protein - Sclerotinia
sclerotiorum 1980
Length = 666
Score = 32.3 bits (70), Expect = 9.7
Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 2/145 (1%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATG-ASERRPHSSRCVGHHESTGDARRS 195
L L + D G S A + Q + S G ++ A+ + + HH TG + S
Sbjct: 381 LRLYNPFDGAGRPSFATHMQTTSRQAVQSNGISSSTAAGNTSRNGLQITHHNGTGRSSTS 440
Query: 196 GENFTSSGTCWDLSSIIRLC-QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVEN 372
++ SG C+ S L E ++ EM V + F + P+ T
Sbjct: 441 HQHEHRSGACYSTRSRRELAHSESIENMDVEMNPSTVEPVTNF-SRLRHPEPTTLSNFSP 499
Query: 373 IDIGGVTLLRAXPRTTTGXPSSXXR 447
+I L A R TG PS R
Sbjct: 500 YEIQNEYLAEAYMR-QTGGPSLAQR 523
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 542,393,530
Number of Sequences: 1657284
Number of extensions: 9770162
Number of successful extensions: 31204
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 30164
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31169
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45636850930
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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