Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0925
(639 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 117 2e-25
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 111 1e-23
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 101 1e-20
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 101 2e-20
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 100 3e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 100 3e-20
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 96 5e-19
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 96 7e-19
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 96 7e-19
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 1e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 95 1e-18
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 95 1e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 94 2e-18
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 94 3e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 7e-18
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 91 2e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 2e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 91 3e-17
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 90 4e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 89 6e-17
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 88 1e-16
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 88 2e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 87 3e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 86 6e-16
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 85 1e-15
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 83 5e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 7e-15
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 83 7e-15
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 1e-14
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 3e-14
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 77 5e-13
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 75 1e-12
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 74 3e-12
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 72 1e-11
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 70 4e-11
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 1e-10
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 68 2e-10
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 68 2e-10
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 68 2e-10
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 65 2e-09
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 64 4e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 63 5e-09
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 54 2e-06
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 49 1e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 43 0.005
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.005
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 39 0.088
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 37 0.36
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 36 0.62
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 36 0.62
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 36 0.82
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 0.82
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 36 1.1
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 36 1.1
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 36 1.1
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 35 1.9
UniRef50_Q0R568 Cluster: Putative minor structural protein; n=3;... 34 3.3
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 34 3.3
UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chai... 34 3.3
UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-relate... 33 4.4
UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1; ... 33 4.4
UniRef50_Q75DW8 Cluster: ABL095Wp; n=1; Eremothecium gossypii|Re... 33 5.8
UniRef50_Q121P4 Cluster: Cation-transporting ATPase; n=6; Proteo... 33 7.7
UniRef50_A4EC20 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
UniRef50_Q5CWG0 Cluster: Transcription elongation factor, SPT6-l... 33 7.7
UniRef50_Q28WT5 Cluster: GA17407-PA; n=2; Coelomata|Rep: GA17407... 33 7.7
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 117 bits (282), Expect = 2e-25
Identities = 57/78 (73%), Positives = 67/78 (85%)
Frame = +2
Query: 2 ANGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEML 181
A G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA ALR+AGL V+DVS++T PEML
Sbjct: 2 APGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEML 61
Query: 182 GGRVKTLHPAVHAGILAR 235
GGRVKTLHPAVHAGILAR
Sbjct: 62 GGRVKTLHPAVHAGILAR 79
Score = 87.4 bits (207), Expect = 3e-16
Identities = 42/78 (53%), Positives = 52/78 (66%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KNH RVTVVC+P DY V E++ ++ T+L T R + + YD AISDYFRKQ
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQ 196
Query: 585 YSPGQAQLTLRYGMNPHQ 638
YS G +Q+ LRYGMNPHQ
Sbjct: 197 YSKGVSQMPLRYGMNPHQ 214
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/85 (47%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPR-----TTTG 420
DM R + + VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA + T
Sbjct: 87 DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146
Query: 421 SPSSVTRPTTML*SKKSKRTNIIRR 495
P +T + S +SK T++ R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 111 bits (268), Expect = 1e-23
Identities = 55/78 (70%), Positives = 63/78 (80%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTGL+ AK L + GL L+ASGGTA LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 197 TLHPAVHAGILARLSDSD 250
TLHPAVH GILAR S +D
Sbjct: 61 TLHPAVHGGILARKSPAD 78
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/48 (72%), Positives = 39/48 (81%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
DM++ Y + VVVCNLYPFV+TVS P VTV DAVE IDIGGVTLLRA
Sbjct: 81 DMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
Score = 40.3 bits (90), Expect = 0.038
Identities = 31/79 (39%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILS-DYDLAISDYFRK 581
KNH RVTVVCDPADY V +E++ + SRD P R L + Y D
Sbjct: 131 KNHARVTVVCDPADYPRVAEEMEGS--------GSRDTPSRTRLSTTRPYRTTSGDSSAV 182
Query: 582 QYSPGQAQLTLRYGMNPHQ 638
+ YGMNPHQ
Sbjct: 183 AF----PSCLCVYGMNPHQ 197
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 101 bits (243), Expect = 1e-20
Identities = 54/80 (67%), Positives = 62/80 (77%), Gaps = 1/80 (1%)
Frame = +2
Query: 14 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
LALLSVSDKTGL+ LA+SL E G QL++SGGTA AL AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 191 VKTLHPAVHAGILARLSDSD 250
VKTLHP +H GILARL S+
Sbjct: 77 VKTLHPRIHGGILARLECSE 96
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/37 (56%), Positives = 27/37 (72%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+VV N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 111 LVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 101 bits (241), Expect = 2e-20
Identities = 52/76 (68%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Frame = +2
Query: 14 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
LALLSVSDKTGL+ LA++L E G QL++SGGTA AL AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 191 VKTLHPAVHAGILARL 238
VKTLHP +H GILARL
Sbjct: 69 VKTLHPRIHGGILARL 84
Score = 46.0 bits (104), Expect = 8e-04
Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPR-----TTTGSPSSVTRPTTM 453
+VV N YPF QTV++ V++ +A E IDIGG TL RA + T PS + +
Sbjct: 103 LVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARAAAKNYPHVTVLTDPSQYPQYLQL 162
Query: 454 L*SKKSKRTNIIRRLWAQAEISPEGVHSYFRTMTSPYRTTS 576
L S S+ + R A + E V +Y R + Y T S
Sbjct: 163 LSSPSSEAERLAFRFQC-ARRAFEQVLAYDRAIVD-YLTRS 201
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 100 bits (240), Expect = 3e-20
Identities = 47/78 (60%), Positives = 60/78 (76%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTGL+ LA++L ++L+++GGTAT +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 197 TLHPAVHAGILARLSDSD 250
TLHP VH G+L R D
Sbjct: 71 TLHPMVHGGLLGRAGIDD 88
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/37 (54%), Positives = 28/37 (75%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+++ NLYPF Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 101 LLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 100 bits (239), Expect = 3e-20
Identities = 47/72 (65%), Positives = 60/72 (83%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTGL+ A+SL+ G++LI++GGTA A+ +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 197 TLHPAVHAGILA 232
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 43.6 bits (98), Expect = 0.004
Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 9/87 (10%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFR-- 578
KNH+ V VV D DYDAV++++ ++ TTL R + + YD AIS++F
Sbjct: 141 KNHEDVAVVVDVNDYDAVLEDLARHE-GSTTLLLRRRLAAKAYARTAAYDAAISNWFAAT 199
Query: 579 -KQYSP------GQAQLTLRYGMNPHQ 638
+ +P G+ +LRYG NPHQ
Sbjct: 200 IQNDAPDYRAFGGRLIQSLRYGENPHQ 226
Score = 40.3 bits (90), Expect = 0.038
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
MK ++V NLYPF TV + +D +ENIDIGG ++RA
Sbjct: 93 MKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 96.3 bits (229), Expect = 5e-19
Identities = 46/80 (57%), Positives = 61/80 (76%)
Frame = +2
Query: 5 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLG 184
N K AL+SVSDK GL+ AK+L + G+++I++GGTA L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 185 GRVKTLHPAVHAGILARLSD 244
GRVKTLHP + GILA L D
Sbjct: 62 GRVKTLHPKIFGGILADLGD 81
Score = 39.9 bits (89), Expect = 0.051
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEI 470
KNH V VVCDPADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
Score = 39.5 bits (88), Expect = 0.067
Identities = 24/49 (48%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKP-DVTVADAVENIDIGGVTLLRA 399
D++ E +VV NLYPF + K D V +ENIDIGGV LLRA
Sbjct: 87 DLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRA 133
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 95.9 bits (228), Expect = 7e-19
Identities = 45/72 (62%), Positives = 58/72 (80%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTGL A +LS+ G++L+++GGT AL AGL V++VS++T PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 197 TLHPAVHAGILA 232
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
Score = 38.3 bits (85), Expect = 0.15
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++V NLYPF +T+ K D VENID+GG ++RA
Sbjct: 152 LLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRA 187
Score = 37.9 bits (84), Expect = 0.20
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 10/88 (11%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFR-- 578
KNH V VV D +DY A++ E+ E+ + T T R + + YD AI+++
Sbjct: 190 KNHADVAVVVDVSDYGAILAELAEHDGNLTAT-TRRRLAQKAFSRTASYDAAIANWLAEV 248
Query: 579 --KQYSP------GQAQLTLRYGMNPHQ 638
+ +P G +LRYG NPHQ
Sbjct: 249 EGRDKAPTFKALGGTLAQSLRYGENPHQ 276
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 95.9 bits (228), Expect = 7e-19
Identities = 45/78 (57%), Positives = 58/78 (74%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDK G++ A++LS+ G++L+++GGTA L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 197 TLHPAVHAGILARLSDSD 250
TLHP VH GIL R D
Sbjct: 70 TLHPKVHGGILGRRGQDD 87
Score = 59.3 bits (137), Expect = 8e-08
Identities = 26/49 (53%), Positives = 36/49 (73%)
Frame = +1
Query: 253 GDMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
G M + + +VV NLYPF QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 88 GIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 95.5 bits (227), Expect = 1e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 197 TLHPAVHAGILAR 235
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/55 (52%), Positives = 37/55 (67%), Gaps = 3/55 (5%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPR---TTTGSPSSVTRP 444
+VV NLYPF TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 98 LVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 95.5 bits (227), Expect = 1e-18
Identities = 43/81 (53%), Positives = 59/81 (72%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K ALLSVSDKTG++ A+ L G+++I++GGTA LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 191 VKTLHPAVHAGILARLSDSDQ 253
VKTLHP +H G+L +Q
Sbjct: 63 VKTLHPRIHGGLLCLRESKEQ 83
Score = 49.2 bits (112), Expect = 8e-05
Identities = 21/45 (46%), Positives = 32/45 (71%)
Frame = +1
Query: 265 RQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++ + ++ NLYPF TVS+ +V + +A+ENIDIGG TLLR+
Sbjct: 89 KEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
Score = 32.7 bits (71), Expect = 7.7
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 7/85 (8%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN+ VTV+ DP+DY ++KE++ + T + + +DYD AI Y +
Sbjct: 136 KNYRSVTVLSDPSDYGRILKELRSSGIISDK--TRAELAVKAFRHTADYDAAIDTYLSRT 193
Query: 585 YSPGQA-------QLTLRYGMNPHQ 638
+ + LRYG N HQ
Sbjct: 194 LLGEEVLHLKFADGVKLRYGENWHQ 218
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 95.5 bits (227), Expect = 1e-18
Identities = 51/83 (61%), Positives = 62/83 (74%), Gaps = 2/83 (2%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGG 187
+LALLSVSDK+G++ LA+ L +E LI+SGGTA L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 188 RVKTLHPAVHAGILARLS-DSDQ 253
RVKTLHP +H GILAR SDQ
Sbjct: 63 RVKTLHPRIHGGILARRDLPSDQ 85
Score = 57.6 bits (133), Expect = 2e-07
Identities = 26/48 (54%), Positives = 34/48 (70%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
D++ +VV NLYPF QT++KP VTVA+AVE IDIGG ++RA
Sbjct: 87 DLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134
Score = 33.5 bits (73), Expect = 4.4
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFR-- 578
KN TV+ +P Y+A ++ ++E + L + + + YD AI++YF
Sbjct: 137 KNFAHTTVLTNPNQYEAYLQALQEQG--EIPLALRQQFAGEAFALTNAYDQAIANYFSGL 194
Query: 579 -----KQYS-PGQAQLTLRYGMNPHQ 638
Q+ G + LRYG NPHQ
Sbjct: 195 SGDSANQFGLSGTLRQPLRYGENPHQ 220
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 94.3 bits (224), Expect = 2e-18
Identities = 44/75 (58%), Positives = 56/75 (74%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 191 VKTLHPAVHAGILAR 235
VKTLHPA+H GILAR
Sbjct: 63 VKTLHPAIHGGILAR 77
Score = 37.5 bits (83), Expect = 0.27
Identities = 21/51 (41%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Frame = +1
Query: 253 GDMKRQKYEMXSVVVCNLYPFVQTVSK--PDVTVADAVENIDIGGVTLLRA 399
G + Q +V NLYPF +TV++ PD V +ENIDIGG ++R+
Sbjct: 84 GQLAAQDIGTIDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRS 131
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 93.9 bits (223), Expect = 3e-18
Identities = 46/80 (57%), Positives = 56/80 (70%)
Frame = +2
Query: 14 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRV 193
L L SVSDKTGL A L G IASGGTA L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 194 KTLHPAVHAGILARLSDSDQ 253
KTLHP +H GILAR + D+
Sbjct: 63 KTLHPMIHGGILARDTKEDR 82
Score = 58.8 bits (136), Expect = 1e-07
Identities = 25/48 (52%), Positives = 34/48 (70%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++K + +V+ NLYPF +T+S PD T +D +ENIDIGGV LLRA
Sbjct: 84 ELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 13/91 (14%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFR-- 578
KN+ RVTV+CDPADYD V EI+ K + +L + + + + YD AI+ +
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIE--KTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSGL 191
Query: 579 KQYSPGQAQLT-----------LRYGMNPHQ 638
+ S G + T LRYG NPHQ
Sbjct: 192 SRLSGGIEEKTSLTLCAYPGQDLRYGENPHQ 222
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 92.7 bits (220), Expect = 7e-18
Identities = 45/79 (56%), Positives = 57/79 (72%)
Frame = +2
Query: 14 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRV 193
LALLSV DKTG+L LA++L + +++SGGTA ALR AG+ +DVS+ T PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 194 KTLHPAVHAGILARLSDSD 250
KTLHP VH G+L R D
Sbjct: 63 KTLHPKVHGGLLGRRGIDD 81
Score = 34.7 bits (76), Expect = 1.9
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 8/86 (9%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIK------ENKHHQTTLGTSRD*P*RRSL--ILSDYDLA 560
KN+ V V+ DP+DY ++ IK E K T +R ++ L+ D
Sbjct: 132 KNYKDVAVLTDPSDYPMAIEAIKTGGFTSEQKLRLATKAFTRTAAYDAAISNYLNGIDKE 191
Query: 561 ISDYFRKQYSPGQAQLTLRYGMNPHQ 638
D + Q+ G+ LRYG NPHQ
Sbjct: 192 FPDVYTMQFGNGR---KLRYGENPHQ 214
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 91.1 bits (216), Expect = 2e-17
Identities = 43/73 (58%), Positives = 56/73 (76%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SV DKTG+L LAK L G ++++SGGT T L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 197 TLHPAVHAGILAR 235
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
Score = 34.3 bits (75), Expect = 2.5
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 11/89 (12%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KNH RV+V+ D DY ++++K N Q + + + S YD I+ YF K
Sbjct: 133 KNHKRVSVLTDIEDYGWFIEKLKMNAVSQQ---DRKYLALKAFWLTSYYDAVIASYFSKV 189
Query: 585 YS-----------PGQAQLTLRYGMNPHQ 638
+ P + LRYG NPHQ
Sbjct: 190 FGFSEKDFKHHTVPMFLRDELRYGENPHQ 218
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 91.1 bits (216), Expect = 2e-17
Identities = 42/72 (58%), Positives = 55/72 (76%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SV DKTGL LAK L E G++++++G TA + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 197 TLHPAVHAGILA 232
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 41.1 bits (92), Expect = 0.022
Identities = 21/41 (51%), Positives = 26/41 (63%)
Frame = +1
Query: 277 EMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
E +VV NLYPFV+TV K D VE IDIGG ++R+
Sbjct: 102 EAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 90.6 bits (215), Expect = 3e-17
Identities = 39/71 (54%), Positives = 54/71 (76%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SVSDKTG++ A L ++++++GGTA LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 197 TLHPAVHAGIL 229
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/47 (40%), Positives = 31/47 (65%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
M+ E +VV +LYPF +T+ V++A+A+E IDIGG ++R+
Sbjct: 97 MREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 90.2 bits (214), Expect = 4e-17
Identities = 42/75 (56%), Positives = 55/75 (73%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+S+SDKT L L L E G ++++GGT++AL AG++V V ++T PEML GR
Sbjct: 89 KQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEMLDGR 148
Query: 191 VKTLHPAVHAGILAR 235
VKTLHP+VH GILAR
Sbjct: 149 VKTLHPSVHGGILAR 163
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/47 (46%), Positives = 31/47 (65%), Gaps = 3/47 (6%)
Frame = +1
Query: 268 QKYEMXS--VVVCNLYPFVQTVSKPD-VTVADAVENIDIGGVTLLRA 399
+K+E+ + VVV NLYPF VS ++ D +ENIDIGG ++RA
Sbjct: 174 EKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
Score = 34.7 bits (76), Expect = 1.9
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 10/88 (11%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KNH V VV D DY A+++ ++ + Q R + ++ YD A+S++ KQ
Sbjct: 223 KNHRDVLVVVDSEDYPALLEFLRGDNDDQQ---FRRKLAWKAFQHVASYDSAVSEWLWKQ 279
Query: 585 -----YSPG-----QAQLTLRYGMNPHQ 638
+ PG + LRYG NPHQ
Sbjct: 280 TVGDKFPPGLTVPLHLKSLLRYGENPHQ 307
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 89.4 bits (212), Expect = 6e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSV +K+G++ +K LS G LI++GGTA +L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 197 TLHPAVHAGILAR 235
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 61.3 bits (142), Expect = 2e-08
Identities = 27/51 (52%), Positives = 37/51 (72%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPR 408
D+ + + S+VV NLYPFV+TVSK T+ +A+ENIDIGG TL+RA +
Sbjct: 84 DLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRASSK 134
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 88.2 bits (209), Expect = 1e-16
Identities = 38/80 (47%), Positives = 56/80 (70%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDKT ++ AK L E G +++++GGT ++ AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 191 VKTLHPAVHAGILARLSDSD 250
VKTLHP +H G+L + S+ +
Sbjct: 63 VKTLHPMIHGGLLGKRSNHE 82
Score = 52.0 bits (119), Expect = 1e-05
Identities = 23/47 (48%), Positives = 31/47 (65%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
M+ +V NLYPF +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 87 MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 87.8 bits (208), Expect = 2e-16
Identities = 39/75 (52%), Positives = 55/75 (73%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDK G++ A+ L++ G ++I++GGT AL AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 191 VKTLHPAVHAGILAR 235
VKTLHP +H G+LAR
Sbjct: 63 VKTLHPKIHGGLLAR 77
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/40 (57%), Positives = 31/40 (77%)
Frame = +1
Query: 280 MXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+ +VV NLYPF +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KNH VTVV DPADY V+ EI E +T+ T + + + YD I+DYF KQ
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAE--QGETSYATRQRLAAKVFRHTAAYDALIADYFTKQ 193
Query: 585 YSPGQAQ-LTLRYGMN 629
+ + LT+ Y +N
Sbjct: 194 VGEDKPEKLTITYDLN 209
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 87.0 bits (206), Expect = 3e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 191 VKTLHPAVHAGILA 232
VKTLHP +H+GILA
Sbjct: 77 VKTLHPFIHSGILA 90
Score = 41.1 bits (92), Expect = 0.022
Identities = 23/52 (44%), Positives = 32/52 (61%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPRTTTGSPSSVTRP 444
+VVCNLYPF TV+ + + VE IDIGG +++RA + S + VT P
Sbjct: 111 LVVCNLYPFQDTVAS-GASFDECVEQIDIGGPSMVRAAAKNHP-SVAVVTSP 160
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 87.0 bits (206), Expect = 3e-16
Identities = 43/78 (55%), Positives = 54/78 (69%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTG++ A+ L + G++L+++GGTA L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 197 TLHPAVHAGILARLSDSD 250
TLHP VH GIL R D
Sbjct: 69 TLHPKVHGGILGRRGTDD 86
Score = 61.3 bits (142), Expect = 2e-08
Identities = 28/47 (59%), Positives = 36/47 (76%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
M++ E +VV NLYPF TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 89 MQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 86.2 bits (204), Expect = 6e-16
Identities = 40/72 (55%), Positives = 54/72 (75%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSV+DK+GL+ A L++ G++L+++GGT L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 197 TLHPAVHAGILA 232
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 85.4 bits (202), Expect = 1e-15
Identities = 42/80 (52%), Positives = 54/80 (67%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K ALLSV DKTG++ LA++L + +++SGGT TAL AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 191 VKTLHPAVHAGILARLSDSD 250
VKTLHP VH G+L R D
Sbjct: 92 VKTLHPKVHGGLLGRRQIDD 111
Score = 34.3 bits (75), Expect = 2.5
Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKEN---KHHQTTLGTSRD*P*RRSLILSDYDLAISDYF 575
KN V VV DP+DY VVK + N H Q + + + YD AIS++
Sbjct: 162 KNFKDVAVVVDPSDYPEVVKTLSSNVGFSHEQRLIFAK-----KAFARTAAYDAAISNHL 216
Query: 576 RKQYSPGQAQLT--------LRYGMNPHQ 638
+ LT LRYG NPHQ
Sbjct: 217 SNLDNTFPPILTLQFTNGRMLRYGENPHQ 245
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 85.4 bits (202), Expect = 1e-15
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K A+LSVS+KTG++ AK+L++ +L ++GGT L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 191 VKTLHPAVHAGILA 232
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 62.9 bits (146), Expect = 6e-09
Identities = 27/48 (56%), Positives = 37/48 (77%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++ Q ++ +VV NLYPF QTV+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 85.4 bits (202), Expect = 1e-15
Identities = 42/74 (56%), Positives = 55/74 (74%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SV DK G+L LAK L + +++I+SGGT L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 191 VKTLHPAVHAGILA 232
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 39.9 bits (89), Expect = 0.051
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++ ++ VV NLYPF + V + D++ + VE IDIGG T+LRA
Sbjct: 87 LEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
Score = 36.3 bits (80), Expect = 0.62
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 8/86 (9%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYF--- 575
KN V V+ D DY+ V+ EIKEN + + + + ++S YD AIS++
Sbjct: 135 KNFKDVVVLSDKKDYEKVMNEIKEN--NCVSFKLRKTLAGKVFNLMSAYDAAISNFLLEG 192
Query: 576 RKQY----SPGQAQL-TLRYGMNPHQ 638
++Y S ++ LRYG NPHQ
Sbjct: 193 EEEYPEYLSVSYKKIQDLRYGENPHQ 218
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 85.4 bits (202), Expect = 1e-15
Identities = 40/73 (54%), Positives = 55/73 (75%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
A++SV K G+ LAK+L E G +++++GGTA LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 197 TLHPAVHAGILAR 235
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 39.5 bits (88), Expect = 0.067
Identities = 21/48 (43%), Positives = 31/48 (64%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++++ + VVV NLYPF + + K +T D +E IDIGG TL+RA
Sbjct: 84 EIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRA 130
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN RV ++ DP DYD V++++K+ TL + + YD IS F+K
Sbjct: 133 KNFFRVVILVDPEDYDWVIEKLKKG---NLTLQDRAYLAWKAFSHTAYYDGVISQAFKKL 189
Query: 585 YS----------PGQAQLTLRYGMNPHQ 638
YS P + LRYG NPHQ
Sbjct: 190 YSIDTFGKEEALPLKRMQKLRYGENPHQ 217
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 84.6 bits (200), Expect = 2e-15
Identities = 38/78 (48%), Positives = 53/78 (67%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDK G++ K L G +++++GGT L+ G+ V +VSD T +PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 197 TLHPAVHAGILARLSDSD 250
TLHP +H GIL + SD +
Sbjct: 63 TLHPKIHGGILHKRSDEN 80
Score = 36.7 bits (81), Expect = 0.47
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN+ V V+CDP DY+ V++ +K+ ++ + + + ++YD I++Y ++
Sbjct: 133 KNYKDVMVLCDPLDYEKVIETLKKGQNDE---NFRLNLMIKAYEHTANYDAYIANYMNER 189
Query: 585 YS---------PGQAQLTLRYGMNPHQ 638
++ GQ +YG NPHQ
Sbjct: 190 FNGGFGASKFIVGQKVFDTKYGENPHQ 216
Score = 33.5 bits (73), Expect = 4.4
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Frame = +1
Query: 292 VVC-NLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+VC NLYPF +T D + +ENIDIGG ++R+
Sbjct: 95 LVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 83.0 bits (196), Expect = 5e-15
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDK L SL + L++ ++LI+SGGT ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 191 VKTLHPAVHAGILARLSD 244
VKTLHP +HAGIL++ +D
Sbjct: 72 VKTLHPKIHAGILSKRND 89
Score = 41.1 bits (92), Expect = 0.022
Identities = 17/48 (35%), Positives = 31/48 (64%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++K +Y+ +V+ N YPF +T+ + + +ENID+GG T++RA
Sbjct: 95 ELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRA 141
Score = 35.5 bits (78), Expect = 1.1
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYF--- 575
KN++ VTV+ Y+ ++ E++ NK T++ + YD IS+YF
Sbjct: 144 KNYNDVTVITSSDQYETLINELENNK-GSTSIEFREKMSLEAFSETAYYDAVISNYFNKI 202
Query: 576 ------RKQYSPGQAQLTLRYGMNPHQ 638
+K+ G LRYG NPHQ
Sbjct: 203 KKNNFPKKKIIYGNLIEKLRYGENPHQ 229
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 82.6 bits (195), Expect = 7e-15
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 191 VKTLHPAVHAGILAR 235
VKTLHP +HAG+LAR
Sbjct: 72 VKTLHPKIHAGLLAR 86
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
++V NLYPFVQTVS + ++ AVE IDIGG ++LRA
Sbjct: 104 LLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRA 140
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 10/88 (11%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN VTVV DP DY +++EIK + H TTL T + + LS YD I+ Y ++
Sbjct: 143 KNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRKRLAQKTFEHLSYYDAHIATYLAEK 201
Query: 585 Y----------SPGQAQLTLRYGMNPHQ 638
S + ++ LRYG NPHQ
Sbjct: 202 EGATTLPARLPSIFKKKIDLRYGENPHQ 229
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 82.6 bits (195), Expect = 7e-15
Identities = 38/78 (48%), Positives = 56/78 (71%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDK+GL+ AK L++ G+++I++GGT L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 191 VKTLHPAVHAGILARLSD 244
VKTLHP VH G+L +S+
Sbjct: 65 VKTLHPKVHGGLLGVISN 82
Score = 56.4 bits (130), Expect = 5e-07
Identities = 24/47 (51%), Positives = 36/47 (76%)
Frame = +1
Query: 259 MKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
M+ K +VV NLYPF++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 89 MEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.2 bits (194), Expect = 1e-14
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 197 TLHPAVHAGILAR 235
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
Score = 37.5 bits (83), Expect(2) = 0.011
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN+ ++ D DYD ++ EI H +L T + + + YD ISDYF+ Q
Sbjct: 139 KNYKNTVIIVDNNDYDNILNEI-NTLHGSISLNTRLNLAAKAFKYIKQYDTMISDYFQHQ 197
Query: 585 --YSPGQAQLTLRYGMNP 632
P + T++ + P
Sbjct: 198 LKLQPNKPHHTIQKRIQP 215
Score = 23.8 bits (49), Expect(2) = 0.011
Identities = 8/10 (80%), Positives = 9/10 (90%)
Frame = +3
Query: 609 TLRYGMNPHQ 638
T+RYG NPHQ
Sbjct: 237 TMRYGENPHQ 246
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 81.4 bits (192), Expect = 2e-14
Identities = 36/74 (48%), Positives = 54/74 (72%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDKT L+ K L+E G+++I++GGT L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 191 VKTLHPAVHAGILA 232
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
Score = 54.0 bits (124), Expect = 3e-06
Identities = 24/37 (64%), Positives = 30/37 (81%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+VV NLYPF +T+SK DVT +A+ENIDIGG +LRA
Sbjct: 98 LVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 47.6 bits (108), Expect = 3e-04
Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 9/87 (10%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRK- 581
KNH VTV+ DPADY V+ +IKE +L R+ + + YD I+DY
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTAAYDALIADYLTNV 194
Query: 582 --QYSPGQAQLT------LRYGMNPHQ 638
+ P Q +T LRYG NPHQ
Sbjct: 195 VGEKEPEQFTVTFEKKQSLRYGENPHQ 221
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 80.6 bits (190), Expect = 3e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 191 VKTLHPAVHAGILA 232
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
Score = 41.1 bits (92), Expect = 0.022
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPRTTT 417
+VV NLYPF + + +D +E IDIGG L+RA + T
Sbjct: 102 LVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHT 144
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/78 (46%), Positives = 54/78 (69%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SV K G+ LA++ + G +++++G TA L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 197 TLHPAVHAGILARLSDSD 250
TLHP +HAGILA +++ +
Sbjct: 71 TLHPYIHAGILADMTNPE 88
Score = 38.3 bits (85), Expect = 0.15
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 396
+VV NLYPF TV + AD +E IDIGG +++R
Sbjct: 103 LVVVNLYPFADTV-RSGANEADTIEKIDIGGPSMVR 137
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/79 (49%), Positives = 55/79 (69%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SVSDK+ L LA+ L ++++++GGT AL G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 197 TLHPAVHAGILARLSDSDQ 253
TLHP +H GILA +++ Q
Sbjct: 77 TLHPKIHGGILALPTEAHQ 95
Score = 54.0 bits (124), Expect = 3e-06
Identities = 22/37 (59%), Positives = 31/37 (83%)
Frame = +1
Query: 289 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+V+ NLYPF +T++KP + ADA+ENIDIGG T++RA
Sbjct: 108 LVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRA 144
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 73.7 bits (173), Expect = 3e-12
Identities = 36/74 (48%), Positives = 50/74 (67%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
+ AL+SVSDKTG+ SLAK+L + ++LI + GT L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 191 VKTLHPAVHAGILA 232
VKTLHP +H GIL+
Sbjct: 69 VKTLHPKIHGGILS 82
Score = 42.3 bits (95), Expect = 0.009
Identities = 17/46 (36%), Positives = 28/46 (60%)
Frame = +1
Query: 262 KRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
K + +V+ N YPF + V K ++ + + ++NIDIGGV L R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/78 (50%), Positives = 51/78 (65%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
ALLSVSDKTGLL LAK+L+ ++LIASGGTA AL AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 197 TLHPAVHAGILARLSDSD 250
T+ + + +L R D +
Sbjct: 67 TISFEIASSLLFRRQDEN 84
Score = 41.9 bits (94), Expect = 0.013
Identities = 22/41 (53%), Positives = 26/41 (63%)
Frame = +1
Query: 277 EMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
E +VV NLYPF T+ K + +ENIDIGG TLLRA
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRA 134
Score = 40.7 bits (91), Expect = 0.029
Identities = 28/78 (35%), Positives = 40/78 (51%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN VTV+CDP+ Y +KE N + TT + + + YD+AI+ + +
Sbjct: 137 KNFHSVTVLCDPSQYSEFLKEFNGN-NGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQ- 194
Query: 585 YSPGQAQLTLRYGMNPHQ 638
+ G A LRYG NPHQ
Sbjct: 195 -NSGAA---LRYGENPHQ 208
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 70.1 bits (164), Expect = 4e-11
Identities = 33/73 (45%), Positives = 46/73 (63%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVK 196
AL+SV K GL + L+ G++ +++GGT + + G + V D+T P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 197 TLHPAVHAGILAR 235
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 36.3 bits (80), Expect = 0.62
Identities = 16/39 (41%), Positives = 26/39 (66%)
Frame = +1
Query: 280 MXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 396
+ +V+ +LYPF TV+ + D +E IDIGG++L+R
Sbjct: 100 LIDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIR 137
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 68.5 bits (160), Expect = 1e-10
Identities = 37/80 (46%), Positives = 51/80 (63%)
Frame = +2
Query: 14 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRV 193
LA+L+VSDK + LA L G ++A+ GT LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 194 KTLHPAVHAGILARLSDSDQ 253
KTL ++ GILAR +D+
Sbjct: 62 KTLTVSLMGGILARDEPADR 81
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/78 (42%), Positives = 47/78 (60%)
Frame = +2
Query: 2 ANGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEML 181
+ K AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++L
Sbjct: 19 SGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKIL 78
Query: 182 GGRVKTLHPAVHAGILAR 235
G VKTLHP + GIL R
Sbjct: 79 DGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/78 (42%), Positives = 47/78 (60%)
Frame = +2
Query: 2 ANGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEML 181
+ K AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++L
Sbjct: 19 SGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKIL 78
Query: 182 GGRVKTLHPAVHAGILAR 235
G VKTLHP + GIL R
Sbjct: 79 DGHVKTLHPNIQGGILPR 96
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 67.7 bits (158), Expect = 2e-10
Identities = 35/82 (42%), Positives = 50/82 (60%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K AL+SV K GL + L E G++ +++GGT + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 191 VKTLHPAVHAGILARLSDSDQE 256
VKTLHP + GIL R D +Q+
Sbjct: 68 VKTLHPKIFGGILCR-RDLEQD 88
Score = 42.7 bits (96), Expect = 0.007
Identities = 21/46 (45%), Positives = 32/46 (69%), Gaps = 2/46 (4%)
Frame = +1
Query: 268 QKYEMXSV--VVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+KYE+ + V+ +LYPF TV+ + AD +E IDIGG++L+RA
Sbjct: 93 EKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRA 137
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 64.9 bits (151), Expect = 2e-09
Identities = 34/84 (40%), Positives = 50/84 (59%)
Frame = +2
Query: 5 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLG 184
N K A++SV DKT L LA L G+++I + GT L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 185 GRVKTLHPAVHAGILARLSDSDQE 256
GRVK++ P + GILA+ +D E
Sbjct: 62 GRVKSIDPKLAGGILAKSNDKKHE 85
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 63.7 bits (148), Expect = 4e-09
Identities = 33/73 (45%), Positives = 45/73 (61%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K L+S+ +K L + + L E G ++ AS GTA L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 191 VKTLHPAVHAGIL 229
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 63.3 bits (147), Expect = 5e-09
Identities = 29/75 (38%), Positives = 48/75 (64%)
Frame = +2
Query: 11 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGR 190
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 191 VKTLHPAVHAGILAR 235
+KTLH ++A ILA+
Sbjct: 68 IKTLHHKIYASILAQ 82
Score = 38.3 bits (85), Expect = 0.15
Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +1
Query: 268 QKYE--MXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
+KY + +VV N YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 91 EKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/78 (42%), Positives = 50/78 (64%)
Frame = +2
Query: 20 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVKT 199
L+SVSD +GL L + L+ + A+ GT L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 200 LHPAVHAGILARLSDSDQ 253
LHPAV +GIL+R + +
Sbjct: 61 LHPAVFSGILSRRDEQSE 78
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/48 (45%), Positives = 32/48 (66%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 399
D+KR Y +V+CNLY F + K ++ D +ENIDIGG++L+RA
Sbjct: 80 DLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/51 (52%), Positives = 33/51 (64%)
Frame = +1
Query: 256 DMKRQKYEMXSVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAEPR 408
DMKR +VV NLYPF QTV++PDVT A NIDIGG ++RA +
Sbjct: 106 DMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRASAK 156
Score = 39.9 bits (89), Expect = 0.051
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Frame = +2
Query: 20 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATALRN-----AGLTVQDVSDITXAPEM 178
L+SVSDKTGL L + + ++GGT + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 179 LGGRVKTLHPAVHAGIL 229
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
Score = 37.1 bits (82), Expect = 0.36
Identities = 23/60 (38%), Positives = 33/60 (55%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTSRD*P*RRSLILSDYDLAISDYFRKQ 584
KN RV V DPADY+ V E+ E++ +L T + + + YD AI+DY +KQ
Sbjct: 156 KNFLRVASVVDPADYNTVADEM-EHRQGALSLDTRFELAQKAFDHTAAYDRAIADYLKKQ 214
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +2
Query: 20 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVKT 199
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 200 LHPAVHAGILA 232
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -1
Query: 396 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTD 295
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 43.2 bits (97), Expect = 0.005
Identities = 21/49 (42%), Positives = 28/49 (57%)
Frame = -1
Query: 396 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHHAXHLVLLTFHVSW 250
A+ G AAD+DVLD + HG V R ERV+V HH L + H+ +
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHHVDGLDAVLLHLGY 460
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.1 bits (87), Expect = 0.088
Identities = 24/67 (35%), Positives = 33/67 (49%)
Frame = -3
Query: 220 SMYRWM*SFHPTSEHLRCXRDVRHILNCEAGVPKRRGGTATGNQLQATFRQALC*RE*TR 41
+M+ + P H R DV H+L+ +A + R GG A G QL A RQ + T
Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTG 539
Query: 40 LV*NAEK 20
LV N E+
Sbjct: 540 LVGNGEE 546
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 37.1 bits (82), Expect = 0.36
Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Frame = +1
Query: 67 PVGMWPAVDCQ--WRYRHGASERRPH-----SSRCVGHHEXTGDARRSGEN-FTSSGTCW 222
P WP CQ WR ++ P VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 223 DLSSIIRL*PGDMKRQKYEMXSVVVCNLYPFVQTVSKPDV 342
D S + R K+ E SV V N + VSKP +
Sbjct: 247 DSSPLHRE-VQQRKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 36.3 bits (80), Expect = 0.62
Identities = 22/36 (61%), Positives = 23/36 (63%)
Frame = -1
Query: 396 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH 289
AQ G AADVDVLD V L +RL ERVQV HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 36.3 bits (80), Expect = 0.62
Identities = 20/42 (47%), Positives = 24/42 (57%)
Frame = +2
Query: 35 DKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 160
DK ++LAK G QL+A+ GTATAL GL V V I
Sbjct: 946 DKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 35.9 bits (79), Expect = 0.82
Identities = 22/74 (29%), Positives = 34/74 (45%)
Frame = +2
Query: 35 DKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLGGRVKTLHPAV 214
DK + LA+ G +L+A+ GTA AG+T V + P L +++ H V
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIV 1007
Query: 215 HAGILARLSDSDQE 256
+ LSD+ E
Sbjct: 1008 MVVNITNLSDAASE 1021
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 0.82
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +2
Query: 176 MLGGRVKTLHPAVHAGILAR 235
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.5 bits (78), Expect = 1.1
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +2
Query: 17 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGL 136
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.5 bits (78), Expect = 1.1
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +2
Query: 20 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI-TXAPEML 181
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/43 (34%), Positives = 30/43 (69%)
Frame = +2
Query: 32 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 160
SDK ++ K+L++ G++L+A+ GTA L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 34.7 bits (76), Expect = 1.9
Identities = 24/51 (47%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +2
Query: 5 NGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDV 151
+GK ALLS+ DK LL +AK L G + A+ GTA AL+ AG+ Q V
Sbjct: 74 SGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_Q0R568 Cluster: Putative minor structural protein; n=3;
root|Rep: Putative minor structural protein -
Streptococcus phage MM1 1998
Length = 504
Score = 33.9 bits (74), Expect = 3.3
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +3
Query: 405 KNHDRVTVVCDPADYDAVVKEIKENKHHQ--TTLGTSRD*P 521
+N DRV V D + YD ++ EIK+ K + TLG RD P
Sbjct: 372 RNDDRVQVFFDGSHYDFIIPEIKDKKSAKIHITLGALRDWP 412
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 33.9 bits (74), Expect = 3.3
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 35 DKTGLLSLAKSLSECGLQLIASGGTATALRN 127
DK GL+ +A+SL E G +L A+ GTA LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chain;
n=155; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 1081
Score = 33.9 bits (74), Expect = 3.3
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +2
Query: 32 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 160
SDK + +A++L G ++A+ GTA+A+ AG+ V+ V+ +
Sbjct: 960 SDKPRAIEVARTLHTLGYPIVATRGTASAIEAAGIPVRVVNKV 1002
>UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-related
protein; n=2; Proteobacteria|Rep: Probable
hemagglutinin/hemolysin-related protein - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 4106
Score = 33.5 bits (73), Expect = 4.4
Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Frame = -2
Query: 455 SIVVGRVTDDGDPV---VVLGSARRRVTPPMSMFSTASATVTSGLDTVWTNGYRLQTTT 288
S VV VTDD DPV +V GS+ TP ++ + A +T+ TV+ NG + T T
Sbjct: 257 SPVVASVTDDVDPVTGAIVSGSSTNDATPTLAGTAEAGSTI-----TVYDNGTAIGTAT 310
>UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1;
Magnetospirillum magneticum AMB-1|Rep: Putative
uncharacterized protein - Magnetospirillum magneticum
(strain AMB-1 / ATCC 700264)
Length = 309
Score = 33.5 bits (73), Expect = 4.4
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Frame = +2
Query: 92 IASGGTATALRNAGLTVQDVSDITXAPEM-LGGRVKTLHPAVHAGILARLSD 244
+ + GT T RN+ TV+ SDIT A + +GG T+ A+ AG++ R +D
Sbjct: 58 VQNSGTITEARNSWGTVKTGSDITEASIVNIGGIETTIKAAMAAGMVTRNAD 109
>UniRef50_Q75DW8 Cluster: ABL095Wp; n=1; Eremothecium gossypii|Rep:
ABL095Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1021
Score = 33.1 bits (72), Expect = 5.8
Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 2/143 (1%)
Frame = +1
Query: 10 KTSSSQRFRQDGSTLVSKEPVGMWPAVDCQWRYRHGASERRPHSSRCVGHHEXTGDARRS 189
K SSS+ F D S EP + P + ++ + P+S T
Sbjct: 850 KRSSSKSFIFDDSDTEDSEPDSIVPPPQISHSLSNDSNTKSPYSIPTRNTSASTSPKNIP 909
Query: 190 GENFTSSGTCWDLSSIIRL-*PGDMKRQKYEMXSVV-VCNLYPFVQTVSKPDVTVADAVE 363
NF S G+ +S+ + PG + + M SV+ L P +TVS + +
Sbjct: 910 PPNFGSLGSGNSHASLNHVAIPGYISPRNGSMQSVISEEKLIPATKTVSHTSTSAEETSR 969
Query: 364 NIDIGGVTLLRAEPRTTTGSPSS 432
N+D+ V + R GSP S
Sbjct: 970 NLDLDSVNKTFGDCR--IGSPDS 990
>UniRef50_Q121P4 Cluster: Cation-transporting ATPase; n=6;
Proteobacteria|Rep: Cation-transporting ATPase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 816
Score = 32.7 bits (71), Expect = 7.7
Identities = 16/45 (35%), Positives = 25/45 (55%)
Frame = +2
Query: 50 LSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITXAPEMLG 184
L + + E G+ L A A AL + G TV ++D+T P++LG
Sbjct: 583 LGSPRFMQELGVDLGACAARAQALEDEGRTVSWLADVTVQPQLLG 627
>UniRef50_A4EC20 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 666
Score = 32.7 bits (71), Expect = 7.7
Identities = 19/40 (47%), Positives = 21/40 (52%)
Frame = -1
Query: 396 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHHAXHL 277
AQ G A DVDVLD VR G + + E VQV D L
Sbjct: 515 AQHGGATDVDVLDGVREGDLGVGDGFLELVQVDDDQVDQL 554
>UniRef50_Q5CWG0 Cluster: Transcription elongation factor,
SPT6-like; n=3; Cryptosporidium|Rep: Transcription
elongation factor, SPT6-like - Cryptosporidium parvum
Iowa II
Length = 2232
Score = 32.7 bits (71), Expect = 7.7
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Frame = +1
Query: 478 TNIIRRLWAQAEISPEGVHSYFRTMTSP-YRTTSASNTRPGKPN 606
TN + ++W+ +SP + Y ++ TSP + ++ S T PG PN
Sbjct: 747 TNELFKVWSPHIVSPYVLSLYLKSFTSPQFHCSTPSGTIPGLPN 790
>UniRef50_Q28WT5 Cluster: GA17407-PA; n=2; Coelomata|Rep: GA17407-PA -
Drosophila pseudoobscura (Fruit fly)
Length = 2180
Score = 32.7 bits (71), Expect = 7.7
Identities = 19/48 (39%), Positives = 25/48 (52%)
Frame = -2
Query: 449 VVGRVTDDGDPVVVLGSARRRVTPPMSMFSTASATVTSGLDTVWTNGY 306
+V RV+ G P AR R + P + +T SAT T G+ T T GY
Sbjct: 2041 MVTRVSLPGQPSAAAEQARSRPSLPAKIPTTQSATQTEGVATKCTYGY 2088
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 611,795,392
Number of Sequences: 1657284
Number of extensions: 11637997
Number of successful extensions: 39323
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 37533
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39265
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47711253245
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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