Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0918
(642 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 113 3e-24
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 112 8e-24
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 93 5e-18
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 2e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 87 3e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 84 3e-15
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 6e-15
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 83 7e-15
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 80 4e-14
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 79 7e-14
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 79 9e-14
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 79 9e-14
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 79 1e-13
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 78 2e-13
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 77 4e-13
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 76 6e-13
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 76 6e-13
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 76 8e-13
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 76 8e-13
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 76 8e-13
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 75 1e-12
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 75 1e-12
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 75 2e-12
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 74 3e-12
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 74 3e-12
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 4e-12
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 6e-12
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 70 4e-11
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 1e-10
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 68 2e-10
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 68 2e-10
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 67 4e-10
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 65 1e-09
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 63 5e-09
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 63 5e-09
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 63 6e-09
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 8e-09
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 61 3e-08
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 58 2e-07
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 58 2e-07
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 57 3e-07
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 52 9e-06
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 52 1e-05
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 49 1e-04
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 48 3e-04
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 45 0.001
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 45 0.002
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 41 0.022
UniRef50_Q4SKD5 Cluster: Chromosome 13 SCAF14566, whole genome s... 33 7.7
UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=... 33 7.7
UniRef50_Q5YV02 Cluster: Putative ABC transporter; n=1; Nocardia... 33 7.7
UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Re... 33 7.7
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 113 bits (272), Expect = 3e-24
Identities = 54/80 (67%), Positives = 63/80 (78%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A LR+AG V+DVS++T PEMLGGRVKTLHPAVH GILAR S +D DM++ Y +I
Sbjct: 32 AKTLRDAGWAVRDVSELTGHPEMLGGRVKTLHPAVHGGILARKSPADTADMEKLGYSLIR 91
Query: 195 VVVCNLYPFVQTVSKPDVTV 254
VVVCNLYPFV+TVS P VTV
Sbjct: 92 VVVCNLYPFVKTVSNPSVTV 111
Score = 43.6 bits (98), Expect = 0.004
Identities = 16/27 (59%), Positives = 22/27 (81%)
Frame = +3
Query: 522 YGMNPHQKPAQVFTTRDSLPITTLNGA 602
YGMNPHQ PAQ++T R +LP+ +NG+
Sbjct: 191 YGMNPHQAPAQLYTLRPALPLRVVNGS 217
Score = 39.1 bits (87), Expect = 0.089
Identities = 18/35 (51%), Positives = 22/35 (62%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTR 414
KNH RVTVVC PADY V +E++ + T TR
Sbjct: 131 KNHARVTVVCDPADYPRVAEEMEGSGSRDTPSRTR 165
Score = 33.5 bits (73), Expect = 4.4
Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +2
Query: 257 DAVENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*SKKSKRTNIIRRLWAQG-RD*P*R 433
DAVE IDIGGVTLLRA + + R T + + + + G RD P R
Sbjct: 113 DAVEQIDIGGVTLLRA-------AAKNHARVTVV--CDPADYPRVAEEMEGSGSRDTPSR 163
Query: 434 RSLILRTMTSPYRTTSASNT 493
L + T PYRTTS ++
Sbjct: 164 TRL---STTRPYRTTSGDSS 180
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 112 bits (269), Expect = 8e-24
Identities = 54/80 (67%), Positives = 62/80 (77%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A ALR+AGL V+DVS++T PEMLGGRVKTLHPAVHAGILAR D DM R + +I
Sbjct: 38 AKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIR 97
Query: 195 VVVCNLYPFVQTVSKPDVTV 254
VV CNLYPFV+TV+ P VTV
Sbjct: 98 VVACNLYPFVKTVASPGVTV 117
Score = 94.7 bits (225), Expect = 2e-18
Identities = 55/113 (48%), Positives = 70/113 (61%), Gaps = 2/113 (1%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH RVTVVC P DY V E++ ++ T+L TR++LALKAFTHT+ YD AISDYFRKQ
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQ 196
Query: 490 YSPGQAH*P*D-TV*THIRSRPRYS-RPETACRSRH*TVRWIYQLCDALNAWQ 642
YS G + P + H Y+ +P+ + +I LCDALNAWQ
Sbjct: 197 YSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFI-NLCDALNAWQ 248
Score = 52.4 bits (120), Expect = 9e-06
Identities = 22/33 (66%), Positives = 26/33 (78%)
Frame = +3
Query: 504 SXLTLRYGMNPHQKPAQVFTTRDSLPITTLNGA 602
S + LRYGMNPHQ PAQ++T + LPIT LNGA
Sbjct: 202 SQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGA 234
Score = 33.9 bits (74), Expect = 3.4
Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Frame = +2
Query: 257 DAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPTTML*SKKSKRTNIIRR 400
+AVE IDIGGVTLLRA + T P +T + S +SK T++ R
Sbjct: 119 EAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETR 171
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 93.1 bits (221), Expect = 5e-18
Identities = 46/81 (56%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMI 191
A L+ AG+ V VSD T APE+LGGRVKTLHP +H GILAR SDQ D++ +
Sbjct: 37 AKTLKEAGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILARRDLPSDQADLEANDIRPL 96
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
+VV NLYPF QT++KP VTV
Sbjct: 97 DLVVVNLYPFEQTIAKPGVTV 117
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 91.5 bits (217), Expect = 2e-17
Identities = 40/79 (50%), Positives = 57/79 (72%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L+ AG+ V++VS+ T +PE+LGGRVKTLHP +H GILAR + D+ ++K + I
Sbjct: 35 AKTLQEAGIKVKEVSEYTSSPEILGGRVKTLHPMIHGGILARDTKEDRAELKALGFSGID 94
Query: 195 VVVCNLYPFVQTVSKPDVT 251
+V+ NLYPF +T+S PD T
Sbjct: 95 IVIANLYPFEKTISSPDST 113
Score = 56.0 bits (129), Expect = 7e-07
Identities = 28/56 (50%), Positives = 38/56 (67%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN+ RVTV+C PADYD V EI+ K + +L R+RLA+KAF + YD AI+ +
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIE--KTGEISLSLRKRLAIKAFDLCTRYDAAITSW 187
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 87.4 bits (207), Expect = 3e-16
Identities = 44/81 (54%), Positives = 55/81 (67%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMI 191
A +L + GL VQ VSD+T PEML GRVKTLHP +H G+LAR Q D+ + + I
Sbjct: 34 AKSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLARPELAHHQADLNKYNIKPI 93
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
S+VV NLYPFV+TVSK T+
Sbjct: 94 SIVVVNLYPFVETVSKESTTL 114
Score = 44.0 bits (99), Expect = 0.003
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKE-----NKHHQTTLGTRQRLALKAFTHTSDYDLAISD 474
KN V ++ P+DY + + I+ N TL R++LALKAF H YD A+S
Sbjct: 134 KNFQNVLIIVDPSDYKWIGERIQSSTDSTNVLSSITLEERKKLALKAFQHGCSYDAAVSQ 193
Query: 475 YFRK 486
Y K
Sbjct: 194 YLSK 197
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 83.8 bits (198), Expect = 3e-15
Identities = 41/78 (52%), Positives = 53/78 (67%), Gaps = 1/78 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMISVV 200
L A + V+ VSD+T PE++ GRVKTLHPAVH GILA R ++ Q ++I +V
Sbjct: 38 LDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMV 97
Query: 201 VCNLYPFVQTVSKPDVTV 254
V NLYPF QTV+ PDVT+
Sbjct: 98 VVNLYPFQQTVANPDVTM 115
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/58 (36%), Positives = 34/58 (58%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 483
KN+ VT + PADY V+ ++ + ++ RQ L +K F HT++YD AI +F+
Sbjct: 135 KNYKHVTTIVHPADYHEVLTRLRNDSLDESY---RQSLMIKVFEHTAEYDEAIVRFFK 189
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 83.0 bits (196), Expect = 6e-15
Identities = 44/81 (54%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED-MKRQKYEMI 191
A LR+AGL V DVS+ T PEML GRVKTLHP VH GILAR ++ D + I
Sbjct: 37 AALLRDAGLPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILARRDLAEHMDTIAAHDISRI 96
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
+VV NLYPF TV++PD T+
Sbjct: 97 DLVVVNLYPFQATVARPDCTL 117
Score = 46.4 bits (105), Expect = 6e-04
Identities = 24/51 (47%), Positives = 33/51 (64%)
Frame = +1
Query: 325 VTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
V +V P DY +V E+K N + + TR LA+KAFTHT+ YD AIS++
Sbjct: 146 VGIVTDPEDYAGIVAELKANAN-TLSYKTRFALAVKAFTHTARYDSAISNH 195
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 82.6 bits (195), Expect = 7e-15
Identities = 42/80 (52%), Positives = 52/80 (65%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L +AGL V +VSD T PEM+ GRVKTLHP VH GIL R D M + + I
Sbjct: 41 ARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGQDDGIMAQHGIQPID 99
Query: 195 VVVCNLYPFVQTVSKPDVTV 254
+VV NLYPF QTV++PD ++
Sbjct: 100 IVVVNLYPFAQTVARPDCSL 119
Score = 52.4 bits (120), Expect = 9e-06
Identities = 25/57 (43%), Positives = 35/57 (61%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 480
KNH V +V +DY A++ E+ +N T TR LA+KAF HT+ YD I++YF
Sbjct: 139 KNHKDVAIVVKSSDYPAIITEL-DNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYF 194
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 81.4 bits (192), Expect = 2e-14
Identities = 40/80 (50%), Positives = 52/80 (65%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
AT +R AGL VQDV+D+T PEM+ GRVKTLHP VH G+L R + D M + I
Sbjct: 42 ATIIREAGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLGR-AGIDDAVMAKHGIAPID 100
Query: 195 VVVCNLYPFVQTVSKPDVTV 254
+++ NLYPF Q +K D T+
Sbjct: 101 LLILNLYPFEQITAKKDCTL 120
Score = 41.5 bits (93), Expect = 0.017
Identities = 22/56 (39%), Positives = 31/56 (55%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN RV V P Y ++ E++ + H Q + R LA+ AF H + YD AIS+Y
Sbjct: 140 KNFARVAVATSPDQYPDLLAELQAH-HGQLSAEKRFALAVAAFNHVAQYDAAISNY 194
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 81.0 bits (191), Expect = 2e-14
Identities = 42/81 (51%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMI 191
A AL AG+ V VS+ T APE+LGGRVKTLHP +H GILARL D+ D++ I
Sbjct: 42 AKALSEAGIPVTPVSEHTGAPEILGGRVKTLHPRIHGGILARLERREDRADLEALGIPPI 101
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
+VV N YPF QTV++ V++
Sbjct: 102 QLVVVNFYPFEQTVARAGVSL 122
Score = 35.9 bits (79), Expect = 0.83
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF-RK 486
KN+ VTV+ P+ Y ++ + L R + A +AF YD AI DY R
Sbjct: 142 KNYPHVTVLTDPSQYPQYLQLLSSPSSEAERLAFRFQCARRAFEQVLAYDRAIVDYLTRS 201
Query: 487 QYS-PGQAH*P 516
+ S P QA P
Sbjct: 202 ELSRPSQAPAP 212
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 80.2 bits (189), Expect = 4e-14
Identities = 43/81 (53%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-DQEDMKRQKYEMI 191
A AL AG+ V VS T APE+LGGRVKTLHP +H GILARL S D+ D++ I
Sbjct: 50 AKALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLECSEDRADLEALGIPPI 109
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
+VV N YPF QTV++ V++
Sbjct: 110 QLVVVNFYPFEQTVAQAGVSL 130
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 79.4 bits (187), Expect = 7e-14
Identities = 41/76 (53%), Positives = 51/76 (67%), Gaps = 1/76 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMI 191
A A+ +AGL V+DVSD+T PEM+ GRVKTLHP VH G+LA R +D E MK I
Sbjct: 42 AKAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLAIRGNDEHAEAMKTHGIAPI 101
Query: 192 SVVVCNLYPFVQTVSK 239
++V NLYPF TV +
Sbjct: 102 DLLVVNLYPFEATVER 117
Score = 53.2 bits (122), Expect = 5e-06
Identities = 27/57 (47%), Positives = 39/57 (68%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 480
KNH+ V VV DYDAV++++ ++ TTL R+RLA KA+ T+ YD AIS++F
Sbjct: 141 KNHEDVAVVVDVNDYDAVLEDLARHEG-STTLLLRRRLAAKAYARTAAYDAAISNWF 196
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 79.0 bits (186), Expect = 9e-14
Identities = 39/81 (48%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL-ARLSDSDQEDMKRQKYEMI 191
A LR AG+ V+DVSD+T PEM+ GRVKTLHP +H G+L R S S + M+ E I
Sbjct: 46 AKTLREAGIEVRDVSDVTGFPEMMDGRVKTLHPKIHGGLLGVRDSPSHESSMREHGIEPI 105
Query: 192 SVVVCNLYPFVQTVSKPDVTV 254
+VV +LYPF +T+ V++
Sbjct: 106 DMVVIDLYPFERTIKGAAVSL 126
Score = 33.9 bits (74), Expect = 3.4
Identities = 18/56 (32%), Positives = 30/56 (53%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN V V+ ++Y + +E++ + +L TR+RLA AF T+ YD + Y
Sbjct: 146 KNFHSVAVITNTSEYGPIAEELRAHDC-SLSLHTRRRLAEIAFQRTAQYDSIVFGY 200
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 79.0 bits (186), Expect = 9e-14
Identities = 38/78 (48%), Positives = 51/78 (65%), Gaps = 1/78 (1%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMISV 197
AL AG+T + D+T PEM+ GRVKTLHP +H G+LAR DS + + +I +
Sbjct: 38 ALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDL 97
Query: 198 VVCNLYPFVQTVSKPDVT 251
VV NLYPF +T+ +PDVT
Sbjct: 98 VVVNLYPFKETILRPDVT 115
Score = 66.5 bits (155), Expect = 5e-10
Identities = 34/60 (56%), Positives = 39/60 (65%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH VTVV PADY V+ EI E +T+ TRQRLA K F HT+ YD I+DYF KQ
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAEQG--ETSYATRQRLAAKVFRHTAAYDALIADYFTKQ 193
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 78.6 bits (185), Expect = 1e-13
Identities = 42/80 (52%), Positives = 50/80 (62%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L L V +VSD T PEM+ GRVKTLHP VH GIL R +D M++ E I
Sbjct: 40 AKLLAQNALPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGTDDAIMQQHGIEGID 98
Query: 195 VVVCNLYPFVQTVSKPDVTV 254
+VV NLYPF TV+KPD T+
Sbjct: 99 MVVVNLYPFAATVAKPDCTL 118
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/63 (38%), Positives = 39/63 (61%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH V +V D++A++ E+ ++++ T TR LA+KAF HT+ YD I++YF +
Sbjct: 138 KNHKDVAIVVNNHDFNAILAEMDQHQN-SLTFETRFDLAIKAFEHTAQYDSMIANYFGQL 196
Query: 490 YSP 498
P
Sbjct: 197 VKP 199
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 78.2 bits (184), Expect = 2e-13
Identities = 37/79 (46%), Positives = 52/79 (65%), Gaps = 1/79 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMI 191
A LR+A + V DVS++T PEM+GGRVKTLHP +H G+L R S E+ ++ +I
Sbjct: 36 AKILRDADIEVTDVSEVTGYPEMMGGRVKTLHPRIHGGLLCLRESKEQMEEAAKEDISLI 95
Query: 192 SVVVCNLYPFVQTVSKPDV 248
++ NLYPF TVS+ +V
Sbjct: 96 DLIAVNLYPFEITVSRENV 114
Score = 50.8 bits (116), Expect = 3e-05
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRK 486
KN+ VTV+ P+DY ++KE++ + TR LA+KAF HT+DYD AI Y +
Sbjct: 136 KNYRSVTVLSDPSDYGRILKELRSSGIISDK--TRAELAVKAFRHTADYDAAIDTYLSR 192
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 77.0 bits (181), Expect = 4e-13
Identities = 35/74 (47%), Positives = 50/74 (67%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISVV 200
AL G+ V VS+ T APE+L GRVKTLHP +H GILA +++ Q +++ I +V
Sbjct: 50 ALSELGVAVVKVSEFTGAPEILDGRVKTLHPKIHGGILALPTEAHQRELELHDIAPIDLV 109
Query: 201 VCNLYPFVQTVSKP 242
+ NLYPF +T++KP
Sbjct: 110 IVNLYPFRETIAKP 123
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/66 (34%), Positives = 36/66 (54%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN +RV V+ P DY ++ + + E + R+ +A KAF HT+ YD AI+ Y +
Sbjct: 147 KNWNRVAVIVDPEDYSSLSEVLGETEGTLPE-SFRRNMARKAFAHTAAYDAAIASYLARH 205
Query: 490 YSPGQA 507
G+A
Sbjct: 206 DDAGEA 211
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 76.2 bits (179), Expect = 6e-13
Identities = 37/69 (53%), Positives = 48/69 (69%), Gaps = 1/69 (1%)
Frame = +3
Query: 18 TALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMIS 194
T L+NAG+ +VS++T E+LGGRVKTLHPA+H GIL R + D E++K E I
Sbjct: 35 TYLKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFREDVEKDLEEIKENSIEPID 94
Query: 195 VVVCNLYPF 221
+VV NLYPF
Sbjct: 95 IVVVNLYPF 103
Score = 46.8 bits (106), Expect = 4e-04
Identities = 31/83 (37%), Positives = 42/83 (50%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH RV+V+ DY ++++K N Q R+ LALKAF TS YD I+ YF K
Sbjct: 133 KNHKRVSVLTDIEDYGWFIEKLKMNAVSQQD---RKYLALKAFWLTSYYDAVIASYFSKV 189
Query: 490 YSPGQAH*P*DTV*THIRSRPRY 558
+ + TV +R RY
Sbjct: 190 FGFSEKDFKHHTVPMFLRDELRY 212
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 76.2 bits (179), Expect = 6e-13
Identities = 40/79 (50%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISVVV 203
L AG+ V+ VSD+T PEML GRVKTLHPA+H GILAR + Q I +V
Sbjct: 39 LSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARREAGHLGQLAAQDIGTIDLVC 98
Query: 204 CNLYPFVQTVSK--PDVTV 254
NLYPF +TV++ PD V
Sbjct: 99 VNLYPFRETVARGAPDPEV 117
Score = 46.4 bits (105), Expect = 6e-04
Identities = 24/56 (42%), Positives = 34/56 (60%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KNHD V V+ PADY +++ + + R+RLA KA+ HTS+YD AI+ Y
Sbjct: 134 KNHDAVLVLVDPADYALALQD-------EVSPAERRRLAAKAYRHTSEYDAAITAY 182
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 75.8 bits (178), Expect = 8e-13
Identities = 38/74 (51%), Positives = 49/74 (66%), Gaps = 1/74 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMI 191
A + AG+ VQ+V ++T +PEML GRVKTLHP VH GILA R + E + + E
Sbjct: 45 AKKIAAAGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILADRRVPAHMETLAGMEIEAF 104
Query: 192 SVVVCNLYPFVQTV 233
+VV NLYPFV+TV
Sbjct: 105 DLVVVNLYPFVETV 118
Score = 47.6 bits (108), Expect = 3e-04
Identities = 26/61 (42%), Positives = 33/61 (54%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH V +V P Y VV+ E L TRQRLA KAF HT+ YD A++ + Q
Sbjct: 144 KNHAAVAIVTDPNFYGDVVRAAAEGGFD---LKTRQRLAAKAFAHTASYDTAVATWTASQ 200
Query: 490 Y 492
+
Sbjct: 201 F 201
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 75.8 bits (178), Expect = 8e-13
Identities = 38/75 (50%), Positives = 50/75 (66%), Gaps = 1/75 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL-SDSDQEDMKRQKYEMI 191
++AL AG++V V ++TR PEML GRVKTLHP+VH GILAR + E +++ +
Sbjct: 122 SSALEGAGVSVTKVEELTRFPEMLDGRVKTLHPSVHGGILARRDQEHHMEALEKHEIGTF 181
Query: 192 SVVVCNLYPFVQTVS 236
VVV NLYPF VS
Sbjct: 182 DVVVVNLYPFYAKVS 196
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH V VV DY A+++ ++ + Q R++LA KAF H + YD A+S++ KQ
Sbjct: 223 KNHRDVLVVVDSEDYPALLEFLRGDNDDQQF---RRKLAWKAFQHVASYDSAVSEWLWKQ 279
Query: 490 YSPGQAH*P*DTV*THIRSRPRY 558
+ G P TV H++S RY
Sbjct: 280 -TVGDKFPPGLTVPLHLKSLLRY 301
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 75.8 bits (178), Expect = 8e-13
Identities = 35/78 (44%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-EDMKRQKYEMISV 197
++ AG+ V V ++T PEML GRVKTLHP +H G+L + S+ + M+ I +
Sbjct: 38 SIAEAGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSIDL 97
Query: 198 VVCNLYPFVQTVSKPDVT 251
V NLYPF +TV KPDV+
Sbjct: 98 VAVNLYPFKETVQKPDVS 115
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/60 (41%), Positives = 32/60 (53%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN + V VV P DY+ V+ I T RQ+LA K F HT+ YD I++YF Q
Sbjct: 136 KNFEDVLVVTGPTDYNRVLAAITSETD---TYEFRQQLAAKVFRHTASYDAMIANYFLSQ 192
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 74.9 bits (176), Expect = 1e-12
Identities = 39/76 (51%), Positives = 50/76 (65%), Gaps = 1/76 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQEDMKRQKYEMI 191
A L +AG+ V+ VSD+T PE+LGGRVKTLHP + GILA L D S +D++ E I
Sbjct: 37 AKLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKSHVKDLRDNFIEPI 96
Query: 192 SVVVCNLYPFVQTVSK 239
+VV NLYPF + K
Sbjct: 97 DLVVVNLYPFDEVQKK 112
Score = 50.8 bits (116), Expect = 3e-05
Identities = 27/53 (50%), Positives = 30/53 (56%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 468
KNH V VVC PADYD V+K I + L R+ ALKAF HT YD I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI--DLCGDVQLHDRRMFALKAFYHTMKYDATI 186
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 74.9 bits (176), Expect = 1e-12
Identities = 36/76 (47%), Positives = 52/76 (68%), Gaps = 1/76 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQEDMKRQKYEMISVV 200
L++ G+ + D T PE+L GRVKTLHP VH G+L +S+ + ++ M+ K I +V
Sbjct: 41 LKDNGIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLV 100
Query: 201 VCNLYPFVQTVSKPDV 248
V NLYPF++TVSKP+V
Sbjct: 101 VVNLYPFLKTVSKPEV 116
Score = 36.7 bits (81), Expect = 0.48
Identities = 21/60 (35%), Positives = 30/60 (50%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ V+ P DY + I + + + R KAF+HT+ YD AIS +F KQ
Sbjct: 138 KNYKHTLVLTDPNDYKKIQNLISSSGISEEISASYMR---KAFSHTAMYDAAISSWFYKQ 194
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 74.5 bits (175), Expect = 2e-12
Identities = 37/76 (48%), Positives = 53/76 (69%), Gaps = 1/76 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR-LSDSDQEDMKRQKYEMI 191
A LR G++V++VS+IT PE+L GRVKTLHP VH GIL R + D+E++++ + I
Sbjct: 34 AKYLREKGISVKEVSEITGFPEILEGRVKTLHPVVHGGILFRDWVEKDKEEIEKHGIKPI 93
Query: 192 SVVVCNLYPFVQTVSK 239
VVV NLYPF + + +
Sbjct: 94 DVVVVNLYPFEEKLKE 109
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/62 (45%), Positives = 38/62 (61%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN RV ++ P DYD V++++K+ TL R LA KAF+HT+ YD IS F+K
Sbjct: 133 KNFFRVVILVDPEDYDWVIEKLKKGN---LTLQDRAYLAWKAFSHTAYYDGVISQAFKKL 189
Query: 490 YS 495
YS
Sbjct: 190 YS 191
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/65 (49%), Positives = 50/65 (76%), Gaps = 1/65 (1%)
Frame = +3
Query: 48 QDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFV 224
Q+VS+ T +PE+LGGRVKTLHP +HAGIL++ +D S +++K +Y+ I +V+ N YPF
Sbjct: 56 QEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKSHTKELKANQYDEIDLVIVNFYPFE 115
Query: 225 QTVSK 239
+T+ +
Sbjct: 116 KTLDQ 120
Score = 50.8 bits (116), Expect = 3e-05
Identities = 22/59 (37%), Positives = 40/59 (67%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRK 486
KN++ VTV+ Y+ ++ E++ NK T++ R++++L+AF+ T+ YD IS+YF K
Sbjct: 144 KNYNDVTVITSSDQYETLINELENNKG-STSIEFREKMSLEAFSETAYYDAVISNYFNK 201
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 73.7 bits (173), Expect = 3e-12
Identities = 37/75 (49%), Positives = 47/75 (62%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A ALR AG+ +DVS+ T+ PEM+ GRVKTLHP VH G+L R D + MK E I
Sbjct: 35 AKALREAGIPAKDVSEYTQFPEMMDGRVKTLHPKVHGGLLGR-RGIDDDVMKAHFIEPID 93
Query: 195 VVVCNLYPFVQTVSK 239
++ NLYPF + K
Sbjct: 94 ILCVNLYPFEEMSKK 108
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/56 (42%), Positives = 32/56 (57%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN+ V V+ P+DY ++ IK T + RLA KAFT T+ YD AIS+Y
Sbjct: 132 KNYKDVAVLTDPSDYPMAIEAIKTGGF---TSEQKLRLATKAFTRTAAYDAAISNY 184
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 73.3 bits (172), Expect = 4e-12
Identities = 37/72 (51%), Positives = 49/72 (68%), Gaps = 1/72 (1%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMISV 197
AL AGL V++VS++TR PEM+ GRVKTLHPAVH G+LA R + Q + I +
Sbjct: 93 ALTEAGLAVREVSELTRFPEMMDGRVKTLHPAVHGGLLAVRDNPEHQAALAAHGIGAIDL 152
Query: 198 VVCNLYPFVQTV 233
+V NLYPF +T+
Sbjct: 153 LVVNLYPFEETL 164
Score = 49.2 bits (112), Expect = 8e-05
Identities = 25/56 (44%), Positives = 37/56 (66%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KNH V VV +DY A++ E+ E+ + T TR+RLA KAF+ T+ YD AI+++
Sbjct: 190 KNHADVAVVVDVSDYGAILAELAEHDGNLTAT-TRRRLAQKAFSRTASYDAAIANW 244
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 72.9 bits (171), Expect = 6e-12
Identities = 32/72 (44%), Positives = 47/72 (65%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISVVV 203
L ++G+ + +SDIT ++L GRVKTLHPAV +GIL+R + + D+KR Y +V+
Sbjct: 34 LSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRDEQSEADLKRYNYFDFDIVI 93
Query: 204 CNLYPFVQTVSK 239
CNLY F + K
Sbjct: 94 CNLYNFESYIDK 105
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/53 (37%), Positives = 34/53 (64%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 468
KN+ VTV P DY+ ++K++++ + +L TR+ LAL+AF + YD+ I
Sbjct: 127 KNYQHVTVASSPEDYNIIIKDLRDG---EISLRTRETLALRAFARAAYYDMII 176
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 70.1 bits (164), Expect = 4e-11
Identities = 33/77 (42%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMISVV 200
L+ G+ V +S++T PE++ GR+KTLHP +H G+LA R ++ + + I +V
Sbjct: 40 LQENGVDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLV 99
Query: 201 VCNLYPFVQTVSKPDVT 251
V NLYPF +T+SK DVT
Sbjct: 100 VVNLYPFKETISKEDVT 116
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/56 (46%), Positives = 34/56 (60%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KNH VTV+ PADY V+ +IKE +L ++ LA K F HT+ YD I+DY
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTAAYDALIADY 190
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 68.9 bits (161), Expect = 1e-10
Identities = 36/74 (48%), Positives = 48/74 (64%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L+ L V DV T PE++ GRVKTLHP +HAG+LAR D++ + + + I
Sbjct: 45 AELLKQHQLPVIDVFTYTGFPEIMDGRVKTLHPKIHAGLLAR-RGIDEKTLDQHAIKPID 103
Query: 195 VVVCNLYPFVQTVS 236
++V NLYPFVQTVS
Sbjct: 104 LLVVNLYPFVQTVS 117
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/60 (48%), Positives = 37/60 (61%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN VTVV P DY +++EIK + H TTL TR+RLA K F H S YD I+ Y ++
Sbjct: 143 KNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRKRLAQKTFEHLSYYDAHIATYLAEK 201
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/75 (45%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMI 191
A + AG+ V V D+T PE+L GRVKTLHP +H+GILA + + +E + + +
Sbjct: 50 AARIAAAGVAVTPVDDVTGFPEVLEGRVKTLHPFIHSGILADQRKAAHREQIAQLGIQAF 109
Query: 192 SVVVCNLYPFVQTVS 236
+VVCNLYPF TV+
Sbjct: 110 DLVVCNLYPFQDTVA 124
Score = 39.1 bits (87), Expect = 0.089
Identities = 23/56 (41%), Positives = 30/56 (53%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KNH V VV P Y V + + TL R+ LA +AF HT+ YDLAI+ +
Sbjct: 149 KNHPSVAVVTSPERYADVAEAVAGEGF---TLEQRRVLAAEAFAHTATYDLAIAGW 201
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/71 (47%), Positives = 47/71 (66%), Gaps = 1/71 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMISVV 200
L+ + V+++S+IT PEML GRVKTLHP VHAGILA R + + ++ ++ I V
Sbjct: 39 LKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYV 98
Query: 201 VCNLYPFVQTV 233
V NLYPF + V
Sbjct: 99 VVNLYPFFEKV 109
Score = 38.3 bits (85), Expect = 0.16
Identities = 23/56 (41%), Positives = 31/56 (55%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN V V+ DY+ V+ EIKEN + + R+ LA K F S YD AIS++
Sbjct: 135 KNFKDVVVLSDKKDYEKVMNEIKEN--NCVSFKLRKTLAGKVFNLMSAYDAAISNF 188
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 67.7 bits (158), Expect = 2e-10
Identities = 34/74 (45%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-EDMKRQKYEMI 191
A L G+ V +VSD+T PE L GRVKTLHP +HAGILA +++ + + ++ +
Sbjct: 42 AKKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEHAKQLEEFGIKPF 101
Query: 192 SVVVCNLYPFVQTV 233
+VV NLYPF TV
Sbjct: 102 DLVVVNLYPFADTV 115
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/61 (37%), Positives = 33/61 (54%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH V +V PADY V + + +L R+ LA KAF HT+ YD I+++ K
Sbjct: 141 KNHATVAIVTDPADYALVASRVADGTGF--SLDERKWLAAKAFAHTAAYDATINEWTAKH 198
Query: 490 Y 492
+
Sbjct: 199 W 199
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 66.9 bits (156), Expect = 4e-10
Identities = 33/75 (44%), Positives = 46/75 (61%), Gaps = 1/75 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-EDMKRQKYEMISVV 200
L+ G+ V +VSD T++PE+ GRVKTLHP +H GIL + SD + + K + I +V
Sbjct: 37 LKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENHIKQAKENEILGIDLV 96
Query: 201 VCNLYPFVQTVSKPD 245
NLYPF +T D
Sbjct: 97 CVNLYPFKKTTIMSD 111
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/64 (32%), Positives = 41/64 (64%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ V V+C P DY+ V++ +K+ ++ + R L +KA+ HT++YD I++Y ++
Sbjct: 133 KNYKDVMVLCDPLDYEKVIETLKKGQNDENF---RLNLMIKAYEHTANYDAYIANYMNER 189
Query: 490 YSPG 501
++ G
Sbjct: 190 FNGG 193
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/72 (44%), Positives = 45/72 (62%), Gaps = 1/72 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQEDMKRQKYEMISVV 200
+ + G + V D+TR P MLGGRVKTLHP + GILAR +SD ++ +I +V
Sbjct: 45 ITSLGYACRAVDDLTRYPSMLGGRVKTLHPMIFGGILARRGHESDVREVGEYGLPLIDLV 104
Query: 201 VCNLYPFVQTVS 236
+ +LYPF TV+
Sbjct: 105 IVDLYPFEATVA 116
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 63.3 bits (147), Expect = 5e-09
Identities = 34/67 (50%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = +3
Query: 54 VSDITRAPEMLGGRVKTLHPAVHAGILARL-SDSDQEDMKRQKYEMISVVVCNLYPFVQT 230
VSD T PE GG VKTL ++ G+L ++S DMKR I +VV NLYPF QT
Sbjct: 69 VSDYTGQPETQGGLVKTLDFKIYLGLLTETYNESHARDMKRTGAVAIDMVVVNLYPFSQT 128
Query: 231 VSKPDVT 251
V++PDVT
Sbjct: 129 VARPDVT 135
Score = 56.4 bits (130), Expect = 5e-07
Identities = 30/60 (50%), Positives = 38/60 (63%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN RV V PADY+ V E+ E++ +L TR LA KAF HT+ YD AI+DY +KQ
Sbjct: 156 KNFLRVASVVDPADYNTVADEM-EHRQGALSLDTRFELAQKAFDHTAAYDRAIADYLKKQ 214
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 63.3 bits (147), Expect = 5e-09
Identities = 33/68 (48%), Positives = 40/68 (58%)
Frame = +3
Query: 18 TALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISV 197
TAL AG+ +VS T PEM+ GRVKTLHP VH G+L R D M + I +
Sbjct: 66 TALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLGR-RQIDDAIMAKYGINRIGL 124
Query: 198 VVCNLYPF 221
+V NLYPF
Sbjct: 125 LVVNLYPF 132
Score = 37.9 bits (84), Expect = 0.21
Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRL--ALKAFTHTSDYDLAISDY 477
KN V VV P+DY VVK + N QRL A KAF T+ YD AIS++
Sbjct: 162 KNFKDVAVVVDPSDYPEVVKTLSSN----VGFSHEQRLIFAKKAFARTAAYDAAISNH 215
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 62.9 bits (146), Expect = 6e-09
Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEM--ISV 197
+ + G + V D+T P +LGGRVKTLHP + GIL R D +Q+ + +KYE+ I +
Sbjct: 44 IESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCR-RDLEQDIQQIEKYEIPEIDL 102
Query: 198 VVCNLYPFVQTVS 236
V+ +LYPF TV+
Sbjct: 103 VIVDLYPFEATVA 115
Score = 33.1 bits (72), Expect = 5.9
Identities = 19/57 (33%), Positives = 33/57 (57%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 480
KN++ V +V A Y ++ + E+ ++L R+ +A +AF +S YD AI +YF
Sbjct: 140 KNYNDVIIVASQAQYKPLLDMLMEHGA-TSSLEERRWMAKEAFAVSSHYDSAIFNYF 195
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/69 (44%), Positives = 44/69 (63%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L NAGLTV +SD T PE++ G+VKTLH + AGIL+R + D+ + + + I
Sbjct: 41 ALILTNAGLTVNKISDYTNFPEIMNGQVKTLHHKICAGILSR-KNLDESIIHKYGIQPID 99
Query: 195 VVVCNLYPF 221
+V+ N YPF
Sbjct: 100 MVIVNFYPF 108
Score = 49.6 bits (113), Expect = 6e-05
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ ++ DYD ++ EI H +L TR LA KAF + YD ISDYF+ Q
Sbjct: 139 KNYKNTVIIVDNNDYDNILNEIN-TLHGSISLNTRLNLAAKAFKYIKQYDTMISDYFQHQ 197
Query: 490 --YSPGQAH 510
P + H
Sbjct: 198 LKLQPNKPH 206
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/76 (42%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQEDMKRQKYEMI 191
A +R + V+DVS++T E+L GRVKTLHP +HA ILA S + +++ +
Sbjct: 41 AEFIRGVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQLQQLGVDAF 100
Query: 192 SVVVCNLYPFVQTVSK 239
+VV NLYPF + +SK
Sbjct: 101 DLVVVNLYPFFE-ISK 115
Score = 49.2 bits (112), Expect = 8e-05
Identities = 23/61 (37%), Positives = 38/61 (62%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KNH RV V+ P+DY V+ ++ + R +LA+KA++HTS+YDL IS + ++
Sbjct: 141 KNHTRVVVIVDPSDYIHVINSLERGAPSRL----RHQLAIKAYSHTSEYDLHISRWLSER 196
Query: 490 Y 492
+
Sbjct: 197 F 197
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 57.6 bits (133), Expect = 2e-07
Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-EDMKRQKYEMISVV 200
L AGL V VS +T PE++GGRVKTLHP +H GILA + + +K ++
Sbjct: 96 LTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILADKDNPEHLATLKELGIRTFDLI 155
Query: 201 VCNLYPFVQTVSK 239
NLY F ++
Sbjct: 156 CVNLYNFADAAAR 168
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 57.6 bits (133), Expect = 2e-07
Identities = 28/64 (43%), Positives = 41/64 (64%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISVVV 203
LR+ G+TV VSD+ P +LGGRVKTL ++ GILAR +D+ +++R + +V
Sbjct: 37 LRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILARDEPADRAEVERHGLTRVHLVC 96
Query: 204 CNLY 215
CN Y
Sbjct: 97 CNYY 100
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 57.2 bits (132), Expect = 3e-07
Identities = 27/77 (35%), Positives = 44/77 (57%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMISVVV 203
L G+ VS+ PE++ GRVKTLHP +H GIL+ ++ + + K + I +V+
Sbjct: 45 LLEKGIFSTSVSEYINHPEIINGRVKTLHPKIHGGILS--NNKNINENKNLNIKKIDMVI 102
Query: 204 CNLYPFVQTVSKPDVTV 254
N YPF + V K ++ +
Sbjct: 103 TNFYPFKKKVKKENIKI 119
Score = 32.7 bits (71), Expect = 7.7
Identities = 20/61 (32%), Positives = 29/61 (47%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ VTVV Y + E+ +N + TR + AF ++ YD I +YF K
Sbjct: 139 KNYKYVTVVVNINQYSKLSSEMDKNSG-SVSFKTRFYFSTLAFQYSYSYDKEIFNYFNKI 197
Query: 490 Y 492
Y
Sbjct: 198 Y 198
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 52.4 bits (120), Expect = 9e-06
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-DQEDMKRQKYEMISV 197
AL NA ++ V +T P++L G VKTLHP + GIL R E + V
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPRRDQKHHMEALNEHGIGTFDV 116
Query: 198 VVCNLYPFVQTVSKPDVTV 254
VV NLYPF +P +T+
Sbjct: 117 VVVNLYPFYD--KQPKLTI 133
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 52.0 bits (119), Expect = 1e-05
Identities = 23/69 (33%), Positives = 42/69 (60%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQKYEMIS 194
A L+ + D+++ T PE++ GR+KTLH ++A ILA+ D++ +++ ++
Sbjct: 41 ANFLKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQ-PKHDKKTIEKYNIILMD 99
Query: 195 VVVCNLYPF 221
+VV N YPF
Sbjct: 100 IVVINFYPF 108
Score = 36.3 bits (80), Expect = 0.63
Identities = 21/60 (35%), Positives = 31/60 (51%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ V VV P Y ++V E+ N + + T+ + A AF HT +YD I Y K+
Sbjct: 139 KNYKNVLVVTQPNLYQSIVNEMNLNNNIISET-TKLKFATIAFKHTMNYDNNIYQYLSKK 197
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 48.8 bits (111), Expect = 1e-04
Identities = 26/53 (49%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +3
Query: 81 MLGGRVKTLHPAVHAGILARLSDS-DQEDMKRQKYEMISVVVCNLYPFVQTVS 236
ML G VKTLHP +H GILAR E + VVV NLYPF VS
Sbjct: 1 MLDGHVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPFYDKVS 53
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 47.6 bits (108), Expect = 3e-04
Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
Frame = +3
Query: 24 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQEDMKRQKYEMISVV 200
L+ G+ ++D PE+LGGRVK++ P + GILA+ +D +EDM + I +V
Sbjct: 40 LQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSNDKKHEEDMINYNIKRIDMV 99
Query: 201 VCNLYPFVQTVSK 239
V N +P + ++K
Sbjct: 100 VGN-FPTFEEIAK 111
Score = 37.9 bits (84), Expect = 0.21
Identities = 20/62 (32%), Positives = 32/62 (51%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRKQ 489
KN+ V + P DY V+ +++ L R++LALK F TS YD +I F +
Sbjct: 136 KNYKDVVALADPKDYQTVIDNLEDCG--DVPLQLRRKLALKVFFSTSKYDASIHKIFSEL 193
Query: 490 YS 495
++
Sbjct: 194 FA 195
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/44 (50%), Positives = 28/44 (63%)
Frame = +3
Query: 3 NSARATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 134
+S A L++ G+ DVS IT +LGG VKTLHP + AGIL
Sbjct: 31 SSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGIL 74
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +3
Query: 15 ATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQEDMKRQKYEMI 191
A AL AGL V V ++ E GR+KT+ + + +L R D +D E I
Sbjct: 38 AKALTEAGLKVTAVETLSGKGEAFNGRMKTISFEIASSLLFRRQDENDVRQAAELGIEPI 97
Query: 192 SVVVCNLYPFVQTVSK 239
+VV NLYPF T+ K
Sbjct: 98 DLVVVNLYPFHATLQK 113
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +1
Query: 310 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 477
KN VTV+C P+ Y +KE N + TT RQ+ A +T T+ YD+AI+ +
Sbjct: 137 KNFHSVTVLCDPSQYSEFLKEFNGN-NGSTTWEFRQKCAAAVYTMTAFYDMAIAGF 191
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 41.1 bits (92), Expect = 0.022
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +3
Query: 21 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 140
AL NA ++ V +T P++L G VKTLHP + GIL R
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPR 96
>UniRef50_Q4SKD5 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 624
Score = 32.7 bits (71), Expect = 7.7
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 5/77 (6%)
Frame = -1
Query: 369 FDYSIVVGRVTDDGDPVVVL---GXARRRVTPPMSMFS--TASXRSRPA*IPSGRTGTGY 205
F +SI++G+V +P VL + R PP + R+RP P+ T +
Sbjct: 296 FAFSIMMGQVRQKVEPRFVLLFGSPSNRSPAPPHRCVTWWARPRRARPTTAPAWTTPSNT 355
Query: 204 RPPRLSSRTSDVSCLPG 154
PP S RTS PG
Sbjct: 356 CPPTASPRTSRTESKPG 372
>UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=1;
Leifsonia xyli subsp. xyli|Rep: Flagellar
hook-associated protein 3 - Leifsonia xyli subsp. xyli
Length = 290
Score = 32.7 bits (71), Expect = 7.7
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = +1
Query: 343 PADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLA 465
PA+ D++VK I++ K + L Q L F TSD D A
Sbjct: 107 PANQDSIVKSIEQLKQNLLALANTQYLGRSVFAGTSDADTA 147
>UniRef50_Q5YV02 Cluster: Putative ABC transporter; n=1; Nocardia
farcinica|Rep: Putative ABC transporter - Nocardia
farcinica
Length = 586
Score = 32.7 bits (71), Expect = 7.7
Identities = 13/26 (50%), Positives = 20/26 (76%)
Frame = -3
Query: 550 AGF*CGFIPYLKVSXLARASIACGSS 473
AG CGF+PYL ++ +ARA +A G++
Sbjct: 36 AGAVCGFLPYLAIAEIARAVLAGGTA 61
>UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
Similarity - Yarrowia lipolytica (Candida lipolytica)
Length = 337
Score = 32.7 bits (71), Expect = 7.7
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Frame = -1
Query: 210 GYRPPRLSSRTSDVSCLPGQS-RIIELRSQHVPLDVKFSPDLRA 82
GY ++ + CL G S I + + PLDV F+PDLR+
Sbjct: 217 GYISAAVNVANGQIFCLLGHSLAICDFAGNYTPLDVHFNPDLRS 260
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 600,376,285
Number of Sequences: 1657284
Number of extensions: 11185430
Number of successful extensions: 32352
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 31049
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32277
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48126133708
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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