Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0876
(645 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 116 5e-25
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 111 1e-23
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 101 1e-20
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 100 3e-20
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 100 3e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 5e-20
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 98 1e-19
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 96 7e-19
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 1e-18
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 95 1e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 1e-18
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 95 2e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 94 3e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 94 3e-18
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 4e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 4e-18
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 91 3e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 3e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 90 4e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 90 5e-17
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 88 2e-16
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 87 3e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 87 5e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 87 5e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 86 8e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 86 8e-16
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 86 8e-16
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 85 1e-15
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 83 6e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 7e-15
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 7e-15
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 83 7e-15
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 80 4e-14
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 76 6e-13
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 75 1e-12
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 74 3e-12
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 8e-12
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 72 1e-11
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 70 6e-11
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 70 6e-11
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 70 6e-11
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 67 3e-10
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 65 1e-09
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 63 5e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 63 6e-09
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 61 3e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 53 5e-06
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 48 1e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 41 0.022
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 40 0.051
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.068
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 37 0.48
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 36 0.84
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 36 0.84
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 0.84
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 36 1.1
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 36 1.1
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 35 1.5
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 35 1.9
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 34 2.6
UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1; ... 34 3.4
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 34 3.4
UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chai... 34 3.4
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 116 bits (279), Expect = 5e-25
Identities = 56/76 (73%), Positives = 66/76 (86%)
Frame = +1
Query: 13 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGG 192
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA ALR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 193 RVKTLHPAVHAGILAR 240
RVKTLHPAVHAGILAR
Sbjct: 64 RVKTLHPAVHAGILAR 79
Score = 83.8 bits (198), Expect = 3e-15
Identities = 53/133 (39%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Frame = +3
Query: 261 DMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 425
DM R + +I VV C LYPFV+TV+ P VTV +AVE IDIGGVTLLRA + T
Sbjct: 87 DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146
Query: 426 SPSSVTRPTTML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQ 605
P +T + S +SK T++ R + ++ I S G
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETRRQLALK-----AFTHTAQYDEAISDYFRKQYSKGV 201
Query: 606 AQLTLRYGMNPHQ 644
+Q+ LRYGMNPHQ
Sbjct: 202 SQMPLRYGMNPHQ 214
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 111 bits (267), Expect = 1e-23
Identities = 55/78 (70%), Positives = 63/78 (80%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTGL+ AK L + GL L+ASGGTA LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 202 TLHPAVHAGILARLSDSD 255
TLHPAVH GILAR S +D
Sbjct: 61 TLHPAVHGGILARKSPAD 78
Score = 74.1 bits (174), Expect = 3e-12
Identities = 35/48 (72%), Positives = 39/48 (81%)
Frame = +3
Query: 261 DMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
DM++ Y +I VVVC LYPFV+TVS P VTV DAVE IDIGGVTLLRA
Sbjct: 81 DMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
Score = 37.9 bits (84), Expect = 0.21
Identities = 27/57 (47%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +2
Query: 410 KNHDRVTVVCXPADYDAVVKEIKENKHHQTTLGQG-RD*P*RRSLILXTXTSPYRXT 577
KNH RVTVVC PADY V +E++ G G RD P R L + T PYR T
Sbjct: 131 KNHARVTVVCDPADYPRVAEEME---------GSGSRDTPSRTRL---STTRPYRTT 175
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 101 bits (242), Expect = 1e-20
Identities = 54/80 (67%), Positives = 62/80 (77%), Gaps = 1/80 (1%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
LALLSVSDKTGL+ LA+SL E G QL++SGGTA AL AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 196 VKTLHPAVHAGILARLSDSD 255
VKTLHP +H GILARL S+
Sbjct: 77 VKTLHPRIHGGILARLECSE 96
Score = 45.6 bits (103), Expect = 0.001
Identities = 44/137 (32%), Positives = 59/137 (43%), Gaps = 18/137 (13%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPT 452
I +VV YPF QTV++ V++ +A E IDIGG TL RA + T PS R
Sbjct: 109 IQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARAAAKNYPYVTVLTDPSQYPRYL 168
Query: 453 TML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQA-------Q 611
+L + + R A + E V +Y ++ L + S A Q
Sbjct: 169 QLLSGAYGETERLAFRFQC-ARRAFEQVLAYDRAIVTYLARLELAGPSQSSAAAAEDRFQ 227
Query: 612 L------TLRYGMNPHQ 644
L LRYG NPHQ
Sbjct: 228 LQGILWQRLRYGENPHQ 244
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 100 bits (240), Expect = 3e-20
Identities = 52/76 (68%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
LALLSVSDKTGL+ LA++L E G QL++SGGTA AL AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 196 VKTLHPAVHAGILARL 243
VKTLHP +H GILARL
Sbjct: 69 VKTLHPRIHGGILARL 84
Score = 45.6 bits (103), Expect = 0.001
Identities = 44/139 (31%), Positives = 59/139 (42%), Gaps = 20/139 (14%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPT 452
I +VV YPF QTV++ V++ +A E IDIGG TL RA + T PS +
Sbjct: 101 IQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARAAAKNYPHVTVLTDPSQYPQYL 160
Query: 453 TML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQAQLT----- 617
+L S S+ + R A + E V +Y ++ S S A T
Sbjct: 161 QLLSSPSSEAERLAFRFQC-ARRAFEQVLAYDRAIVDYLTRSELSRPSQAPAPATAAEQV 219
Query: 618 ----------LRYGMNPHQ 644
LRYG NPHQ
Sbjct: 220 FQLQGIPWQRLRYGENPHQ 238
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 100 bits (239), Expect = 3e-20
Identities = 47/78 (60%), Positives = 60/78 (76%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTGL+ LA++L ++L+++GGTAT +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 202 TLHPAVHAGILARLSDSD 255
TLHP VH G+L R D
Sbjct: 71 TLHPMVHGGLLGRAGIDD 88
Score = 46.4 bits (105), Expect = 6e-04
Identities = 20/39 (51%), Positives = 28/39 (71%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
I +++ LYPF Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 99 IDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 99 bits (238), Expect = 5e-20
Identities = 47/72 (65%), Positives = 60/72 (83%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTGL+ A+SL+ G++LI++GGTA A+ +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 202 TLHPAVHAGILA 237
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 40.7 bits (91), Expect = 0.029
Identities = 21/49 (42%), Positives = 28/49 (57%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
E MK I ++V LYPF TV + +D +ENIDIGG ++RA
Sbjct: 91 EAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 98.3 bits (234), Expect = 1e-19
Identities = 46/72 (63%), Positives = 59/72 (81%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTGL A +LS+ G++L+++GGT AL AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 202 TLHPAVHAGILA 237
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
Score = 38.3 bits (85), Expect = 0.16
Identities = 37/130 (28%), Positives = 51/130 (39%), Gaps = 11/130 (8%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPT 452
I ++V LYPF +T+ K D VENID+GG ++RA + S
Sbjct: 150 IDLLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRAAAKNHADVAVVVDVSDYGAIL 208
Query: 453 TML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSP------GQAQL 614
L T RR A+ S SY + + + +P G
Sbjct: 209 AELAEHDGNLTATTRRRLAQKAFSRTA--SYDAAIANWLAEVEGRDKAPTFKALGGTLAQ 266
Query: 615 TLRYGMNPHQ 644
+LRYG NPHQ
Sbjct: 267 SLRYGENPHQ 276
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 95.9 bits (228), Expect = 7e-19
Identities = 46/80 (57%), Positives = 61/80 (76%)
Frame = +1
Query: 10 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLG 189
N K AL+SVSDK GL+ AK+L + G+++I++GGTA L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 190 GRVKTLHPAVHAGILARLSD 249
GRVKTLHP + GILA L D
Sbjct: 62 GRVKTLHPKIFGGILADLGD 81
Score = 39.1 bits (87), Expect = 0.090
Identities = 24/50 (48%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKP-DVTVADAVENIDIGGVTLLRA 404
+D++ E I +VV LYPF + K D V +ENIDIGGV LLRA
Sbjct: 86 KDLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRA 133
Score = 37.1 bits (82), Expect = 0.36
Identities = 15/22 (68%), Positives = 16/22 (72%)
Frame = +2
Query: 410 KNHDRVTVVCXPADYDAVVKEI 475
KNH V VVC PADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 95.5 bits (227), Expect = 1e-18
Identities = 47/80 (58%), Positives = 56/80 (70%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 198
L L SVSDKTGL A L G IASGGTA L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 199 KTLHPAVHAGILARLSDSDR 258
KTLHP +H GILAR + DR
Sbjct: 63 KTLHPMIHGGILARDTKEDR 82
Score = 58.0 bits (134), Expect = 2e-07
Identities = 25/48 (52%), Positives = 34/48 (70%)
Frame = +3
Query: 261 DMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
++K + I +V+ LYPF +T+S PD T +D +ENIDIGGV LLRA
Sbjct: 84 ELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 37.9 bits (84), Expect = 0.21
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +2
Query: 410 KNHDRVTVVCXPADYDAVVKEIKE 481
KN+ RVTV+C PADYD V EI++
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIEK 157
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 95.5 bits (227), Expect = 1e-18
Identities = 45/78 (57%), Positives = 58/78 (74%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDK G++ A++LS+ G++L+++GGTA L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 202 TLHPAVHAGILARLSDSD 255
TLHP VH GIL R D
Sbjct: 70 TLHPKVHGGILGRRGQDD 87
Score = 57.2 bits (132), Expect = 3e-07
Identities = 25/47 (53%), Positives = 35/47 (74%)
Frame = +3
Query: 264 MKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
M + + I +VV LYPF QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 90 MAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 95.1 bits (226), Expect = 1e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 202 TLHPAVHAGILAR 240
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 56.8 bits (131), Expect = 4e-07
Identities = 29/57 (50%), Positives = 37/57 (64%), Gaps = 3/57 (5%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR---TTTGSPSSVTRP 449
I +VV LYPF TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 94.7 bits (225), Expect = 2e-18
Identities = 48/76 (63%), Positives = 59/76 (77%), Gaps = 1/76 (1%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGG 192
+LALLSVSDK+G++ LA+ L +E LI+SGGTA L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 193 RVKTLHPAVHAGILAR 240
RVKTLHP +H GILAR
Sbjct: 63 RVKTLHPRIHGGILAR 78
Score = 60.1 bits (139), Expect = 4e-08
Identities = 42/137 (30%), Positives = 67/137 (48%), Gaps = 7/137 (5%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPS 434
Q D++ + +VV LYPF QT++KP VTVA+AVE IDIGG ++RA + + +
Sbjct: 85 QADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRATAKNFAHT-T 143
Query: 435 SVTRPTTML*SKKSKRTNIIRRLWAKAEISPEG---VHSYXGLXPRHIGLLSASNTS--- 596
+T P ++ + L + + + E ++Y + LS + +
Sbjct: 144 VLTNPNQYEAYLQALQEQGEIPLALRQQFAGEAFALTNAYDQAIANYFSGLSGDSANQFG 203
Query: 597 -PGQAQLTLRYGMNPHQ 644
G + LRYG NPHQ
Sbjct: 204 LSGTLRQPLRYGENPHQ 220
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 93.9 bits (223), Expect = 3e-18
Identities = 42/73 (57%), Positives = 57/73 (78%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K ALLSVSDKTG++ A+ L G+++I++GGTA LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 196 VKTLHPAVHAGIL 234
VKTLHP +H G+L
Sbjct: 63 VKTLHPRIHGGLL 75
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/49 (44%), Positives = 34/49 (69%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
E+ ++ +I ++ LYPF TVS+ +V + +A+ENIDIGG TLLR+
Sbjct: 85 EEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 93.9 bits (223), Expect = 3e-18
Identities = 44/75 (58%), Positives = 56/75 (74%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 196 VKTLHPAVHAGILAR 240
VKTLHPA+H GILAR
Sbjct: 63 VKTLHPAIHGGILAR 77
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/41 (46%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSK--PDVTVADAVENIDIGGVTLLRA 404
I +V LYPF +TV++ PD V +ENIDIGG ++R+
Sbjct: 94 IDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRS 131
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 93.5 bits (222), Expect = 4e-18
Identities = 44/78 (56%), Positives = 57/78 (73%)
Frame = +1
Query: 7 SNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEML 186
S K AL+S+SDKT L L L E G ++++GGT++AL AG++V V ++TR PEML
Sbjct: 86 SGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEML 145
Query: 187 GGRVKTLHPAVHAGILAR 240
GRVKTLHP+VH GILAR
Sbjct: 146 DGRVKTLHPSVHGGILAR 163
Score = 40.7 bits (91), Expect = 0.029
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKPD-VTVADAVENIDIGGVTLLRA 404
E +++ + VVV LYPF VS ++ D +ENIDIGG ++RA
Sbjct: 171 EALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 93.5 bits (222), Expect = 4e-18
Identities = 45/79 (56%), Positives = 58/79 (73%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 198
LALLSV DKTG+L LA++L + +++SGGTA ALR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 199 KTLHPAVHAGILARLSDSD 255
KTLHP VH G+L R D
Sbjct: 63 KTLHPKVHGGLLGRRGIDD 81
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 90.6 bits (215), Expect = 3e-17
Identities = 43/73 (58%), Positives = 56/73 (76%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SV DKTG+L LAK L G ++++SGGT T L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 202 TLHPAVHAGILAR 240
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 90.6 bits (215), Expect = 3e-17
Identities = 42/72 (58%), Positives = 55/72 (76%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SV DKTGL LAK L E G++++++G TA + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 202 TLHPAVHAGILA 237
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 39.9 bits (89), Expect = 0.051
Identities = 21/49 (42%), Positives = 28/49 (57%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
E + + E +VV LYPFV+TV K D VE IDIGG ++R+
Sbjct: 94 ETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 90.2 bits (214), Expect = 4e-17
Identities = 39/71 (54%), Positives = 54/71 (76%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SVSDKTG++ A L ++++++GGTA LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 202 TLHPAVHAGIL 234
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 46.0 bits (104), Expect = 8e-04
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
+ M+ E I +VV LYPF +T+ V++A+A+E IDIGG ++R+
Sbjct: 94 ESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 89.8 bits (213), Expect = 5e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSV +K+G++ +K LS G LI++GGTA +L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 202 TLHPAVHAGILAR 240
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 61.7 bits (143), Expect = 1e-08
Identities = 28/50 (56%), Positives = 37/50 (74%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
Q D+ + + IS+VV LYPFV+TVSK T+ +A+ENIDIGG TL+RA
Sbjct: 82 QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 87.8 bits (208), Expect = 2e-16
Identities = 38/80 (47%), Positives = 56/80 (70%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDKT ++ AK L E G +++++GGT ++ AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 196 VKTLHPAVHAGILARLSDSD 255
VKTLHP +H G+L + S+ +
Sbjct: 63 VKTLHPMIHGGLLGKRSNHE 82
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/47 (48%), Positives = 31/47 (65%)
Frame = +3
Query: 264 MKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
M+ I +V LYPF +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 87 MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 87.4 bits (207), Expect = 3e-16
Identities = 39/75 (52%), Positives = 55/75 (73%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDK G++ A+ L++ G ++I++GGT AL AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 196 VKTLHPAVHAGILAR 240
VKTLHP +H G+LAR
Sbjct: 63 VKTLHPKIHGGLLAR 77
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/40 (57%), Positives = 31/40 (77%)
Frame = +3
Query: 285 MISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
+I +VV LYPF +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 86.6 bits (205), Expect = 5e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 196 VKTLHPAVHAGILA 237
VKTLHP +H+GILA
Sbjct: 77 VKTLHPFIHSGILA 90
Score = 39.5 bits (88), Expect = 0.068
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPS 434
+E + + + +VVC LYPF TV+ + + VE IDIGG +++RA + S +
Sbjct: 98 REQIAQLGIQAFDLVVCNLYPFQDTVAS-GASFDECVEQIDIGGPSMVRAAAKNHP-SVA 155
Query: 435 SVTRP 449
VT P
Sbjct: 156 VVTSP 160
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 86.6 bits (205), Expect = 5e-16
Identities = 43/78 (55%), Positives = 54/78 (69%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTG++ A+ L + G++L+++GGTA L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 202 TLHPAVHAGILARLSDSD 255
TLHP VH GIL R D
Sbjct: 69 TLHPKVHGGILGRRGTDD 86
Score = 60.5 bits (140), Expect = 3e-08
Identities = 28/47 (59%), Positives = 36/47 (76%)
Frame = +3
Query: 264 MKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
M++ E I +VV LYPF TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 89 MQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 85.8 bits (203), Expect = 8e-16
Identities = 40/72 (55%), Positives = 54/72 (75%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSV+DK+GL+ A L++ G++L+++GGT L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 202 TLHPAVHAGILA 237
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 85.8 bits (203), Expect = 8e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K A+LSVS+KTG++ AK+L++ +L ++GGT L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 196 VKTLHPAVHAGILA 237
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/48 (56%), Positives = 37/48 (77%)
Frame = +3
Query: 261 DMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
++ Q ++I +VV LYPF QTV+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 85.8 bits (203), Expect = 8e-16
Identities = 38/78 (48%), Positives = 54/78 (69%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDK G++ K L G +++++GGT L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 202 TLHPAVHAGILARLSDSD 255
TLHP +H GIL + SD +
Sbjct: 63 TLHPKIHGGILHKRSDEN 80
Score = 38.7 bits (86), Expect = 0.12
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 7/126 (5%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTG-----SPSSVTRPT 452
I +V LYPF +T D + +ENIDIGG ++R+ + P +
Sbjct: 93 IDLVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRSAAKNYKDVMVLCDPLDYEKVI 151
Query: 453 TML*SKKSKRTNIIRRLWAKAEISPEGVHSYXG--LXPRHIGLLSASNTSPGQAQLTLRY 626
L K N L KA +Y + R G AS GQ +Y
Sbjct: 152 ETL-KKGQNDENFRLNLMIKAYEHTANYDAYIANYMNERFNGGFGASKFIVGQKVFDTKY 210
Query: 627 GMNPHQ 644
G NPHQ
Sbjct: 211 GENPHQ 216
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 85.0 bits (201), Expect = 1e-15
Identities = 42/80 (52%), Positives = 54/80 (67%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K ALLSV DKTG++ LA++L + +++SGGT TAL AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 196 VKTLHPAVHAGILARLSDSD 255
VKTLHP VH G+L R D
Sbjct: 92 VKTLHPKVHGGLLGRRQIDD 111
Score = 35.5 bits (78), Expect = 1.1
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 11/138 (7%)
Frame = +3
Query: 264 MKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPSSVT 443
M + I ++V LYPF + +S+ + + +E ID+GG ++RA + + V
Sbjct: 114 MAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLIEYIDVGGPAMIRAAAKNFK-DVAVVV 171
Query: 444 RPTTML*SKKSKRTNI-----IRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPG-- 602
P+ K+ +N+ R ++AK + +Y H+ L NT P
Sbjct: 172 DPSDYPEVVKTLSSNVGFSHEQRLIFAKKAFARTA--AYDAAISNHLSNLD--NTFPPIL 227
Query: 603 QAQLT----LRYGMNPHQ 644
Q T LRYG NPHQ
Sbjct: 228 TLQFTNGRMLRYGENPHQ 245
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 85.0 bits (201), Expect = 1e-15
Identities = 42/74 (56%), Positives = 55/74 (74%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SV DK G+L LAK L + +++I+SGGT L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 196 VKTLHPAVHAGILA 237
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 39.1 bits (87), Expect = 0.090
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +3
Query: 264 MKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
++ ++ I VV LYPF + V + D++ + VE IDIGG T+LRA
Sbjct: 87 LEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 85.0 bits (201), Expect = 1e-15
Identities = 40/73 (54%), Positives = 55/73 (75%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
A++SV K G+ LAK+L E G +++++GGTA LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 202 TLHPAVHAGILAR 240
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 41.9 bits (94), Expect = 0.013
Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 7/137 (5%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPS 434
+E++++ + I VVV LYPF + + K +T D +E IDIGG TL+RA +
Sbjct: 82 KEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRAAAKNFFRVVI 140
Query: 435 SVTRPTTML*SKKSKRTNII---RRLWAKAEISP----EGVHSYXGLXPRHIGLLSASNT 593
V +K K+ N+ R A S +GV S I
Sbjct: 141 LVDPEDYDWVIEKLKKGNLTLQDRAYLAWKAFSHTAYYDGVISQAFKKLYSIDTFGKEEA 200
Query: 594 SPGQAQLTLRYGMNPHQ 644
P + LRYG NPHQ
Sbjct: 201 LPLKRMQKLRYGENPHQ 217
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 83.0 bits (196), Expect = 6e-15
Identities = 39/82 (47%), Positives = 57/82 (69%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDK+GL+ AK L++ G+++I++GGT L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 196 VKTLHPAVHAGILARLSDSDRK 261
VKTLHP VH G+L +S+ K
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHK 86
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/50 (48%), Positives = 38/50 (76%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
++ M+ K I +VV LYPF++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 86 KQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 82.6 bits (195), Expect = 7e-15
Identities = 42/83 (50%), Positives = 54/83 (65%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 196 VKTLHPAVHAGILARLSDSDRKT 264
VKTLHP +HAG+LAR D KT
Sbjct: 72 VKTLHPKIHAGLLAR-RGIDEKT 93
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/141 (28%), Positives = 65/141 (46%), Gaps = 11/141 (7%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TT 419
++ + + + I ++V LYPFVQTVS + ++ AVE IDIGG ++LRA + T
Sbjct: 91 EKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRAAAKNFAAVTV 150
Query: 420 TGSPSSVTRPTTML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSP 599
P +R + + T R+ A+ E + Y ++ + T P
Sbjct: 151 VVDPEDYSRILEEIKTHHGSTTLSTRKRLAQKTF--EHLSYYDAHIATYLAEKEGATTLP 208
Query: 600 G------QAQLTLRYGMNPHQ 644
+ ++ LRYG NPHQ
Sbjct: 209 ARLPSIFKKKIDLRYGENPHQ 229
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.6 bits (195), Expect = 7e-15
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 202 TLHPAVHAGILAR 240
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 82.6 bits (195), Expect = 7e-15
Identities = 40/78 (51%), Positives = 57/78 (73%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDK L SL + L++ ++LI+SGGT ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 196 VKTLHPAVHAGILARLSD 249
VKTLHP +HAGIL++ +D
Sbjct: 72 VKTLHPKIHAGILSKRND 89
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
Frame = +3
Query: 258 EDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRT---TTGS 428
+++K +Y+ I +V+ YPF +T+ + + +ENID+GG T++RA + T
Sbjct: 94 KELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRAAAKNYNDVTVI 152
Query: 429 PSSVTRPTTML*SKKSK-RTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSP-- 599
SS T + + +K T+I R E E + Y + + + +N
Sbjct: 153 TSSDQYETLINELENNKGSTSIEFREKMSLEAFSETAY-YDAVISNYFNKIKKNNFPKKK 211
Query: 600 ---GQAQLTLRYGMNPHQ 644
G LRYG NPHQ
Sbjct: 212 IIYGNLIEKLRYGENPHQ 229
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 81.0 bits (191), Expect = 2e-14
Identities = 36/74 (48%), Positives = 54/74 (72%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDKT L+ K L+E G+++I++GGT L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 196 VKTLHPAVHAGILA 237
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
Score = 53.6 bits (123), Expect = 4e-06
Identities = 44/130 (33%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Frame = +3
Query: 288 ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPT 452
I +VV LYPF +T+SK DVT +A+ENIDIGG +LRA + T P+ +
Sbjct: 96 IDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRAASKNHQDVTVIVDPADYSPVL 155
Query: 453 TML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQAQLT----- 617
+ + S R L AK +Y L ++ + P Q +T
Sbjct: 156 NQIKEEGSVSLQKKRELAAKVF---RHTAAYDALIADYLTNV-VGEKEPEQFTVTFEKKQ 211
Query: 618 -LRYGMNPHQ 644
LRYG NPHQ
Sbjct: 212 SLRYGENPHQ 221
Score = 34.3 bits (75), Expect = 2.6
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +2
Query: 410 KNHDRVTVVCXPADYDAVVKEIKE 481
KNH VTV+ PADY V+ +IKE
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE 160
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 80.2 bits (189), Expect = 4e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 196 VKTLHPAVHAGILA 237
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
Score = 38.7 bits (86), Expect = 0.12
Identities = 17/47 (36%), Positives = 25/47 (53%)
Frame = +3
Query: 282 EMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTT 422
+ +VV LYPF + + +D +E IDIGG L+RA + T
Sbjct: 98 DAFDLVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHT 144
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 76.2 bits (179), Expect = 6e-13
Identities = 36/78 (46%), Positives = 54/78 (69%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SV K G+ LA++ + G +++++G TA L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 202 TLHPAVHAGILARLSDSD 255
TLHP +HAGILA +++ +
Sbjct: 71 TLHPYIHAGILADMTNPE 88
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 74.9 bits (176), Expect = 1e-12
Identities = 38/88 (43%), Positives = 57/88 (64%), Gaps = 1/88 (1%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
+ AL+SVSDKTG+ SLAK+L + ++LI + GT L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 196 VKTLHPAVHAGILARLSD-SDRKT*NVR 276
VKTLHP +H GIL+ + ++ K N++
Sbjct: 69 VKTLHPKIHGGILSNNKNINENKNLNIK 96
Score = 41.5 bits (93), Expect = 0.017
Identities = 17/46 (36%), Positives = 28/46 (60%)
Frame = +3
Query: 267 KRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
K + I +V+ YPF + V K ++ + + ++NIDIGGV L R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 74.1 bits (174), Expect = 3e-12
Identities = 38/80 (47%), Positives = 56/80 (70%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SVSDK+ L LA+ L ++++++GGT AL G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 202 TLHPAVHAGILARLSDSDRK 261
TLHP +H GILA +++ ++
Sbjct: 77 TLHPKIHGGILALPTEAHQR 96
Score = 58.4 bits (135), Expect = 1e-07
Identities = 46/148 (31%), Positives = 70/148 (47%), Gaps = 18/148 (12%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TT 419
Q +++ I +V+ LYPF +T++KP + ADA+ENIDIGG T++RA +
Sbjct: 95 QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRAAAKNWNRVAV 154
Query: 420 TGSPSSVTRPTTML*S-----KKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRH--IGLL 578
P + + +L +S R N+ R+ +A + SY RH G
Sbjct: 155 IVDPEDYSSLSEVLGETEGTLPESFRRNMARKAFAHTAAYDAAIASYLA---RHDDAGEA 211
Query: 579 SASNTSP------GQAQLTLRYGMNPHQ 644
+ T P G++ LRYG NPHQ
Sbjct: 212 LDAGTIPEGLFVSGESVAELRYGENPHQ 239
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 72.5 bits (170), Expect = 8e-12
Identities = 34/73 (46%), Positives = 47/73 (64%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 202 TLHPAVHAGILAR 240
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 41.1 bits (92), Expect = 0.022
Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 5/125 (4%)
Frame = +3
Query: 285 MISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTG----SPSSVTRPT 452
+I +V+ LYPF TV+ + D +E IDIGG++L+R + S +
Sbjct: 100 LIDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIRGAAKNFEDVVIISSRAQYAGF 158
Query: 453 TML*SKKSKRTNII-RRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQAQLTLRYG 629
L ++ RT++ RR +A+ + + G +A S ++ LRYG
Sbjct: 159 YSLLKEQGARTSLAERRHYAREAFAVSSAYDSAIFRYFDDGEQTAFRMSADSPKV-LRYG 217
Query: 630 MNPHQ 644
NPHQ
Sbjct: 218 ENPHQ 222
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 71.7 bits (168), Expect = 1e-11
Identities = 39/78 (50%), Positives = 51/78 (65%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 201
ALLSVSDKTGLL LAK+L+ ++LIASGGTA AL AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 202 TLHPAVHAGILARLSDSD 255
T+ + + +L R D +
Sbjct: 67 TISFEIASSLLFRRQDEN 84
Score = 45.2 bits (102), Expect = 0.001
Identities = 40/121 (33%), Positives = 52/121 (42%)
Frame = +3
Query: 282 EMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML 461
E I +VV LYPF T+ K + +ENIDIGG TLLRA + S + + P+
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRAGAK-NFHSVTVLCDPSQYS 152
Query: 462 *SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTSPGQAQLTLRYGMNPH 641
K N W + V++ I N+ G A LRYG NPH
Sbjct: 153 EFLKEFNGNNGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQNS--GAA---LRYGENPH 207
Query: 642 Q 644
Q
Sbjct: 208 Q 208
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 69.7 bits (163), Expect = 6e-11
Identities = 38/80 (47%), Positives = 51/80 (63%)
Frame = +1
Query: 19 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 198
LA+L+VSDK + LA L G ++A+ GT LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 199 KTLHPAVHAGILARLSDSDR 258
KTL ++ GILAR +DR
Sbjct: 62 KTLTVSLMGGILARDEPADR 81
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 69.7 bits (163), Expect = 6e-11
Identities = 35/79 (44%), Positives = 48/79 (60%)
Frame = +1
Query: 4 ASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEM 183
AS K AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 184 LGGRVKTLHPAVHAGILAR 240
L G VKTLHP + GIL R
Sbjct: 78 LDGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 69.7 bits (163), Expect = 6e-11
Identities = 35/79 (44%), Positives = 48/79 (60%)
Frame = +1
Query: 4 ASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEM 183
AS K AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 184 LGGRVKTLHPAVHAGILAR 240
L G VKTLHP + GIL R
Sbjct: 78 LDGHVKTLHPNIQGGILPR 96
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 67.3 bits (157), Expect = 3e-10
Identities = 33/75 (44%), Positives = 46/75 (61%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K AL+SV K GL + L E G++ +++GGT + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 196 VKTLHPAVHAGILAR 240
VKTLHP + GIL R
Sbjct: 68 VKTLHPKIFGGILCR 82
Score = 49.6 bits (113), Expect = 6e-05
Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 7/137 (5%)
Frame = +3
Query: 255 QEDMKRQKYEM--ISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTG- 425
Q+ + +KYE+ I +V+ LYPF TV+ + AD +E IDIGG++L+RA +
Sbjct: 87 QDIQQIEKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRAAAKNYNDV 145
Query: 426 ---SPSSVTRPTTML*SKKSKRTNIIRRLWAKAEISPEGVHSYXGLXPR-HIGLLSASNT 593
+ + +P + + +++ R W E H + G SA
Sbjct: 146 IIVASQAQYKPLLDMLMEHGATSSLEERRWMAKEAFAVSSHYDSAIFNYFDAGEGSAFRC 205
Query: 594 SPGQAQLTLRYGMNPHQ 644
S Q LRYG NPHQ
Sbjct: 206 SVNN-QKQLRYGENPHQ 221
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/83 (38%), Positives = 52/83 (62%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 196 VKTLHPAVHAGILARLSDSDRKT 264
+KTLH ++A ILA+ D+KT
Sbjct: 68 IKTLHHKIYASILAQ-PKHDKKT 89
Score = 38.3 bits (85), Expect = 0.16
Identities = 21/60 (35%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Frame = +3
Query: 234 SSIIRL*QEDMKR-QKYEMI--SVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
+SI+ + D K +KY +I +VV YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 77 ASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 63.3 bits (147), Expect = 5e-09
Identities = 33/73 (45%), Positives = 45/73 (61%)
Frame = +1
Query: 16 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 195
K L+S+ +K L + + L E G ++ AS GTA L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 196 VKTLHPAVHAGIL 234
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 62.9 bits (146), Expect = 6e-09
Identities = 33/80 (41%), Positives = 49/80 (61%)
Frame = +1
Query: 10 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLG 189
N K A++SV DKT L LA L G+++I + GT L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 190 GRVKTLHPAVHAGILARLSD 249
GRVK++ P + GILA+ +D
Sbjct: 62 GRVKSIDPKLAGGILAKSND 81
Score = 33.9 bits (74), Expect = 3.4
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
+EDM + I +VV +P + ++K +ENIDIGG +LLRA
Sbjct: 85 EEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLLENIDIGGYSLLRA 133
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/72 (45%), Positives = 48/72 (66%)
Frame = +1
Query: 25 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 204
L+SVSD +GL L + L+ + A+ GT L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 205 LHPAVHAGILAR 240
LHPAV +GIL+R
Sbjct: 61 LHPAVFSGILSR 72
Score = 47.6 bits (108), Expect = 3e-04
Identities = 42/136 (30%), Positives = 58/136 (42%), Gaps = 6/136 (4%)
Frame = +3
Query: 255 QEDMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TT 419
+ D+KR Y +V+C LY F + K ++ D +ENIDIGG++L+RA + T
Sbjct: 78 EADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRAAAKNYQHVTV 134
Query: 420 TGSPSSVTRPTTML*SKK-SKRTNIIRRLWAKAEISPEGVHSYXGLXPRHIGLLSASNTS 596
SP L + S RT L A A + + Y L R
Sbjct: 135 ASSPEDYNIIIKDLRDGEISLRTRETLALRAFARAAYYDMIIYKSLYKRLNNDEPEELFI 194
Query: 597 PGQAQLTLRYGMNPHQ 644
G + LRYG NP Q
Sbjct: 195 HGYDRTKLRYGENPDQ 210
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 53.2 bits (122), Expect = 5e-06
Identities = 27/48 (56%), Positives = 32/48 (66%)
Frame = +3
Query: 261 DMKRQKYEMISVVVCXLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 404
DMKR I +VV LYPF QTV++PDVT A NIDIGG ++RA
Sbjct: 106 DMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRA 153
Score = 39.5 bits (88), Expect = 0.068
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Frame = +1
Query: 25 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATALRN-----AGLTVQDVSDITRAPEM 183
L+SVSDKTGL L + + ++GGT + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 184 LGGRVKTLHPAVHAGIL 234
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +1
Query: 25 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 204
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 205 LHPAVHAGILA 237
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 41.1 bits (92), Expect = 0.022
Identities = 22/34 (64%), Positives = 23/34 (67%)
Frame = -2
Query: 401 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQXTD 300
AQ AADVDVLDRV V LR RLDER+Q D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.9 bits (89), Expect = 0.051
Identities = 24/67 (35%), Positives = 34/67 (50%)
Frame = -1
Query: 225 SMYRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKRRGGTATGNQLQATFRQALC*RE*TR 46
+M+ + P H R + DV H+L+ +A + R GG A G QL A RQ + T
Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTG 539
Query: 45 LV*NAEK 25
LV N E+
Sbjct: 540 LVGNGEE 546
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 39.5 bits (88), Expect = 0.068
Identities = 20/47 (42%), Positives = 26/47 (55%)
Frame = -2
Query: 401 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQXTDHHAYHLVLLTFHV 261
A+ G AAD+DVLD + HG V R ERV+ HH L + H+
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHHVDGLDAVLLHL 458
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 36.7 bits (81), Expect = 0.48
Identities = 23/54 (42%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Frame = +1
Query: 7 SNGKLAL-LSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 165
S+G + L + DK ++LAK G QL+A+ GTATAL GL V V I
Sbjct: 934 SHGNVLLTVRDEDKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 35.9 bits (79), Expect = 0.84
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 8/100 (8%)
Frame = +3
Query: 72 PVGMWPAVDCQ--WRYRHGASERRPH-----SSRCVGHHESTGDARRSGEN-FTSSGTCW 227
P WP CQ WR ++ P VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 228 DLSSIIRL*QEDMKRQKYEMISVVVCXLYPFVQTVSKPDV 347
D S + R Q+ K+ E SV V + VSKP +
Sbjct: 247 DSSPLHREVQQ-RKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.9 bits (79), Expect = 0.84
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +1
Query: 25 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI-TRAPEML 186
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 0.84
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +1
Query: 181 MLGGRVKTLHPAVHAGILAR 240
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.5 bits (78), Expect = 1.1
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +1
Query: 22 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGL 141
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/43 (34%), Positives = 30/43 (69%)
Frame = +1
Query: 37 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 165
SDK ++ K+L++ G++L+A+ GTA L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 35.1 bits (77), Expect = 1.5
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = +1
Query: 40 DKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAV 219
DK + LA+ G +L+A+ GTA AG+T V + P L +++ H V
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIV 1007
Query: 220 HAGILARLSDS 252
+ LSD+
Sbjct: 1008 MVVNITNLSDA 1018
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 34.7 bits (76), Expect = 1.9
Identities = 24/51 (47%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +1
Query: 10 NGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDV 156
+GK ALLS+ DK LL +AK L G + A+ GTA AL+ AG+ Q V
Sbjct: 74 SGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 34.3 bits (75), Expect = 2.6
Identities = 21/36 (58%), Positives = 22/36 (61%)
Frame = -2
Query: 401 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQXTDHH 294
AQ G AADVDVLD V L +RL ERVQ HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1;
Magnetospirillum magneticum AMB-1|Rep: Putative
uncharacterized protein - Magnetospirillum magneticum
(strain AMB-1 / ATCC 700264)
Length = 309
Score = 33.9 bits (74), Expect = 3.4
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Frame = +1
Query: 97 IASGGTATALRNAGLTVQDVSDITRAPEM-LGGRVKTLHPAVHAGILARLSD 249
+ + GT T RN+ TV+ SDIT A + +GG T+ A+ AG++ R +D
Sbjct: 58 VQNSGTITEARNSWGTVKTGSDITEASIVNIGGIETTIKAAMAAGMVTRNAD 109
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 33.9 bits (74), Expect = 3.4
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 40 DKTGLLSLAKSLSECGLQLIASGGTATALRN 132
DK GL+ +A+SL E G +L A+ GTA LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chain;
n=155; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 1081
Score = 33.9 bits (74), Expect = 3.4
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +1
Query: 37 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 165
SDK + +A++L G ++A+ GTA+A+ AG+ V+ V+ +
Sbjct: 960 SDKPRAIEVARTLHTLGYPIVATRGTASAIEAAGIPVRVVNKV 1002
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 604,981,039
Number of Sequences: 1657284
Number of extensions: 11347999
Number of successful extensions: 36278
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 34793
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36244
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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