Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0648
(747 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 115 1e-24
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 109 5e-23
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 99 6e-20
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 99 6e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 1e-19
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 1e-19
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 97 3e-19
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 97 4e-19
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 96 7e-19
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 95 1e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 95 2e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 2e-18
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 5e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 93 7e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 1e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 2e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 91 3e-17
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 4e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 90 5e-17
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 89 1e-16
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 89 1e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 88 2e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 88 2e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 87 6e-16
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 84 3e-15
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 84 3e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 9e-15
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 1e-14
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 82 1e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 3e-14
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 80 5e-14
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 77 5e-13
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 76 1e-12
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 74 3e-12
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 6e-12
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 71 4e-11
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 9e-11
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 69 2e-10
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 67 4e-10
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 67 4e-10
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 65 2e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 64 3e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 64 3e-09
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 63 8e-09
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 56 9e-07
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 48 2e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 43 0.007
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.021
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 40 0.086
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 39 0.11
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 38 0.20
UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:... 37 0.46
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 37 0.61
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 37 0.61
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 36 0.80
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 1.1
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 35 1.8
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 35 1.8
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 34 4.3
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 33 5.6
UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene ... 33 7.5
UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolyti... 33 9.9
UniRef50_Q0R568 Cluster: Putative minor structural protein; n=3;... 33 9.9
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 115 bits (277), Expect = 1e-24
Identities = 55/76 (72%), Positives = 66/76 (86%)
Frame = +2
Query: 14 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA+ LR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 194 RVKTLHPAVHAGILAR 241
RVKTLHPAVHAGILAR
Sbjct: 64 RVKTLHPAVHAGILAR 79
Score = 89.0 bits (211), Expect = 1e-16
Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
KNH RVTVVC+P DY V E++ ++ T+L RR L L+ T + A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190
Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
S G +Q+ LRYGMNPHQ PAQ++T + + NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246
Score = 74.1 bits (174), Expect = 3e-12
Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
Frame = +1
Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
DM R + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA + T
Sbjct: 87 DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146
Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
P +T + S +SK T++ R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/58 (48%), Positives = 34/58 (58%)
Frame = +2
Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
S Q ++ TR++LALKAFTHT+ YD AISDYFRKQY S L+ P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 109 bits (263), Expect = 5e-23
Identities = 54/75 (72%), Positives = 62/75 (82%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTGL+ AK L + GL L+ASGGTA+ LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 203 TLHPAVHAGILARLS 247
TLHPAVH GILAR S
Sbjct: 61 TLHPAVHGGILARKS 75
Score = 95.9 bits (228), Expect = 9e-19
Identities = 57/112 (50%), Positives = 68/112 (60%), Gaps = 1/112 (0%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQG-RD*P*RRSLILRTMTSPYRTTSAS 587
KNH RVTVVCDPADY V +E++ G G RD P R L + T PYRTTS
Sbjct: 131 KNHARVTVVCDPADYPRVAEEME---------GSGSRDTPSRTRL---STTRPYRTTSGD 178
Query: 588 NTSXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
+++ YGMNPHQ PAQ++T R + R NG+PGFINLCDALNA
Sbjct: 179 SSAVAFPSCLCVYGMNPHQAPAQLYTLRPAL-PLRVVNGSPGFINLCDALNA 229
Score = 77.0 bits (181), Expect = 5e-13
Identities = 36/48 (75%), Positives = 40/48 (83%)
Frame = +1
Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
DM++ Y +I VVVCNLYPFV+TVS P VTV DAVE IDIGGVTLLRA
Sbjct: 81 DMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 99 bits (238), Expect = 6e-20
Identities = 51/76 (67%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Frame = +2
Query: 20 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
LALLSVSDKTGL+ LA++L E G QL++SGGTA+ L AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 197 VKTLHPAVHAGILARL 244
VKTLHP +H GILARL
Sbjct: 69 VKTLHPRIHGGILARL 84
Score = 47.2 bits (107), Expect = 4e-04
Identities = 22/39 (56%), Positives = 28/39 (71%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I +VV N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 101 IQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARA 139
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 99 bits (238), Expect = 6e-20
Identities = 53/79 (67%), Positives = 61/79 (77%), Gaps = 1/79 (1%)
Frame = +2
Query: 20 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
LALLSVSDKTGL+ LA+SL E G QL++SGGTA+ L AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 197 VKTLHPAVHAGILARLSDS 253
VKTLHP +H GILARL S
Sbjct: 77 VKTLHPRIHGGILARLECS 95
Score = 46.8 bits (106), Expect = 6e-04
Identities = 22/39 (56%), Positives = 28/39 (71%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I +VV N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 109 IQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 99.1 bits (236), Expect = 1e-19
Identities = 46/72 (63%), Positives = 60/72 (83%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTGL+ A+SL+ G++LI++GGTA+ + +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 203 TLHPAVHAGILA 238
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
E MK I ++V NLYPF TV + +D +ENIDIGG ++RA
Sbjct: 91 EAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
Score = 35.9 bits (79), Expect = 1.1
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGR--D*P*RRSLILRTMTSPYRTTSA 584
KNH+ V VV D DYDAV++++ ++ T L + R R+ S + +
Sbjct: 141 KNHEDVAVVVDVNDYDAVLEDLARHEGSTTLLLRRRLAAKAYARTAAYDAAISNWFAATI 200
Query: 585 SNTS------XGQAQLTLRYGMNPHQKPA 653
N + G+ +LRYG NPHQ A
Sbjct: 201 QNDAPDYRAFGGRLIQSLRYGENPHQHAA 229
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 98.7 bits (235), Expect = 1e-19
Identities = 46/72 (63%), Positives = 59/72 (81%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTGL A +LS+ G++L+++GGT R L AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 203 TLHPAVHAGILA 238
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
Score = 39.9 bits (89), Expect = 0.065
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I ++V NLYPF +T+ K D VENID+GG ++RA
Sbjct: 150 IDLLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRA 187
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 97.5 bits (232), Expect = 3e-19
Identities = 46/82 (56%), Positives = 63/82 (76%)
Frame = +2
Query: 11 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 190
N K AL+SVSDK GL+ AK+L + G+++I++GGTA+ L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 191 GRVKTLHPAVHAGILARLSDSA 256
GRVKTLHP + GILA L D +
Sbjct: 62 GRVKTLHPKIFGGILADLGDKS 83
Score = 41.9 bits (94), Expect = 0.016
Identities = 25/50 (50%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKP-DVTVADAVENIDIGGVTLLRA 405
+D++ E I +VV NLYPF + K D V +ENIDIGGV LLRA
Sbjct: 86 KDLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRA 133
Score = 39.9 bits (89), Expect = 0.065
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEI 476
KNH V VVCDPADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 97.1 bits (231), Expect = 4e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTGL+ LA++L ++L+++GGTA +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 203 TLHPAVHAGILAR 241
TLHP VH G+L R
Sbjct: 71 TLHPMVHGGLLGR 83
Score = 49.2 bits (112), Expect = 1e-04
Identities = 21/39 (53%), Positives = 29/39 (74%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I +++ NLYPF Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 99 IDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 96.3 bits (229), Expect = 7e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDK G++ A++LS+ G++L+++GGTAR L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 203 TLHPAVHAGILAR 241
TLHP VH GIL R
Sbjct: 70 TLHPKVHGGILGR 82
Score = 60.1 bits (139), Expect = 6e-08
Identities = 26/47 (55%), Positives = 36/47 (76%)
Frame = +1
Query: 265 MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
M + + I +VV NLYPF QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 90 MAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
Score = 33.5 bits (73), Expect = 5.6
Identities = 14/26 (53%), Positives = 19/26 (73%)
Frame = +2
Query: 503 FGTRQRLALKAFTHTSDYDLAISDYF 580
+ TR LA+KAF HT+ YD I++YF
Sbjct: 169 YPTRFNLAIKAFEHTAAYDSMIANYF 194
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 95.5 bits (227), Expect = 1e-18
Identities = 48/76 (63%), Positives = 60/76 (78%), Gaps = 1/76 (1%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
+LALLSVSDK+G++ LA+ L +E LI+SGGTA+ L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 194 RVKTLHPAVHAGILAR 241
RVKTLHP +H GILAR
Sbjct: 63 RVKTLHPRIHGGILAR 78
Score = 60.5 bits (140), Expect = 4e-08
Identities = 27/50 (54%), Positives = 36/50 (72%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
Q D++ + +VV NLYPF QT++KP VTVA+AVE IDIGG ++RA
Sbjct: 85 QADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 95.1 bits (226), Expect = 2e-18
Identities = 42/73 (57%), Positives = 58/73 (79%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K ALLSVSDKTG++ A+ L G+++I++GGTA+ LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 197 VKTLHPAVHAGIL 235
VKTLHP +H G+L
Sbjct: 63 VKTLHPRIHGGLL 75
Score = 53.2 bits (122), Expect = 7e-06
Identities = 23/49 (46%), Positives = 35/49 (71%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
E+ ++ +I ++ NLYPF TVS+ +V + +A+ENIDIGG TLLR+
Sbjct: 85 EEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
Score = 35.9 bits (79), Expect = 1.1
Identities = 15/26 (57%), Positives = 18/26 (69%)
Frame = +2
Query: 509 TRQRLALKAFTHTSDYDLAISDYFRK 586
TR LA+KAF HT+DYD AI Y +
Sbjct: 167 TRAELAVKAFRHTADYDAAIDTYLSR 192
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 94.7 bits (225), Expect = 2e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 203 TLHPAVHAGILAR 241
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 59.7 bits (138), Expect = 8e-08
Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR---TTTGSPSSVTRP 450
I +VV NLYPF TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
Score = 33.9 bits (74), Expect = 4.3
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +2
Query: 503 FGTRQRLALKAFTHTSDYDLAISDY 577
+ TR LA+KAFTHT+ YD AIS++
Sbjct: 171 YKTRFALAVKAFTHTARYDSAISNH 195
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 93.5 bits (222), Expect = 5e-18
Identities = 45/74 (60%), Positives = 54/74 (72%)
Frame = +2
Query: 20 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 199
L L SVSDKTGL A L G IASGGTA+ L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 200 KTLHPAVHAGILAR 241
KTLHP +H GILAR
Sbjct: 63 KTLHPMIHGGILAR 76
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/48 (54%), Positives = 35/48 (72%)
Frame = +1
Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
++K + I +V+ NLYPF +T+S PD T +D +ENIDIGGV LLRA
Sbjct: 84 ELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 40.7 bits (91), Expect = 0.037
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKE 482
KN+ RVTV+CDPADYD V EI++
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIEK 157
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 93.1 bits (221), Expect = 7e-18
Identities = 44/75 (58%), Positives = 56/75 (74%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 197 VKTLHPAVHAGILAR 241
VKTLHPA+H GILAR
Sbjct: 63 VKTLHPAIHGGILAR 77
Score = 37.1 bits (82), Expect = 0.46
Identities = 20/41 (48%), Positives = 28/41 (68%), Gaps = 2/41 (4%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSK--PDVTVADAVENIDIGGVTLLRA 405
I +V NLYPF +TV++ PD V +ENIDIGG ++R+
Sbjct: 94 IDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRS 131
Score = 33.9 bits (74), Expect = 4.3
Identities = 14/22 (63%), Positives = 18/22 (81%)
Frame = +2
Query: 512 RQRLALKAFTHTSDYDLAISDY 577
R+RLA KA+ HTS+YD AI+ Y
Sbjct: 161 RRRLAAKAYRHTSEYDAAITAY 182
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 92.3 bits (219), Expect = 1e-17
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +2
Query: 20 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 199
LALLSV DKTG+L LA++L + +++SGGTA+ LR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 200 KTLHPAVHAGILAR 241
KTLHP VH G+L R
Sbjct: 63 KTLHPKVHGGLLGR 76
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 91.9 bits (218), Expect = 2e-17
Identities = 42/72 (58%), Positives = 56/72 (77%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SV DKTGL LAK L E G++++++G TA+ + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 203 TLHPAVHAGILA 238
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 42.7 bits (96), Expect = 0.009
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
E + + E +VV NLYPFV+TV K D VE IDIGG ++R+
Sbjct: 94 ETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
Score = 38.7 bits (86), Expect = 0.15
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 500 DFGTRQRLALKAFTHTSDYDLAISDYFRKQY 592
D TRQRLA KAF HT+ YD A++ + Q+
Sbjct: 171 DLKTRQRLAAKAFAHTASYDTAVATWTASQF 201
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 91.1 bits (216), Expect = 3e-17
Identities = 39/71 (54%), Positives = 55/71 (77%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SVSDKTG++ A L ++++++GGTA+ LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 203 TLHPAVHAGIL 235
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 46.8 bits (106), Expect = 6e-04
Identities = 20/50 (40%), Positives = 33/50 (66%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+ M+ E I +VV +LYPF +T+ V++A+A+E IDIGG ++R+
Sbjct: 94 ESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 90.6 bits (215), Expect = 4e-17
Identities = 43/78 (55%), Positives = 55/78 (70%)
Frame = +2
Query: 8 SNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEML 187
S K AL+S+SDKT L L L E G ++++GGT+ L AG++V V ++TR PEML
Sbjct: 86 SGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEML 145
Query: 188 GGRVKTLHPAVHAGILAR 241
GRVKTLHP+VH GILAR
Sbjct: 146 DGRVKTLHPSVHGGILAR 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKPD-VTVADAVENIDIGGVTLLRA 405
E +++ + VVV NLYPF VS ++ D +ENIDIGG ++RA
Sbjct: 171 EALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
Score = 35.9 bits (79), Expect = 1.1
Identities = 17/44 (38%), Positives = 25/44 (56%)
Frame = +2
Query: 494 SDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKI 625
+DD R++LA KAF H + YD A+S++ KQ P L +
Sbjct: 248 NDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFPPGLTV 291
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 90.2 bits (214), Expect = 5e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSV +K+G++ +K LS G LI++GGTA+ L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 203 TLHPAVHAGILAR 241
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 64.5 bits (150), Expect = 3e-09
Identities = 29/50 (58%), Positives = 38/50 (76%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
Q D+ + + IS+VV NLYPFV+TVSK T+ +A+ENIDIGG TL+RA
Sbjct: 82 QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
Score = 34.3 bits (75), Expect = 3.2
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = +2
Query: 491 SSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARAS 607
SS R++LALKAF H YD A+S Y K A+
Sbjct: 166 SSITLEERKKLALKAFQHGCSYDAAVSQYLSKVELTNAT 204
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 89.0 bits (211), Expect = 1e-16
Identities = 39/78 (50%), Positives = 55/78 (70%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDKT ++ AK L E G +++++GGT R + AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 197 VKTLHPAVHAGILARLSD 250
VKTLHP +H G+L + S+
Sbjct: 63 VKTLHPMIHGGLLGKRSN 80
Score = 54.0 bits (124), Expect = 4e-06
Identities = 24/47 (51%), Positives = 32/47 (68%)
Frame = +1
Query: 265 MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
M+ I +V NLYPF +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 87 MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/63 (31%), Positives = 31/63 (49%)
Frame = +2
Query: 488 TSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEPTSEAGPGIHD 667
+ +D + RQ+LA K F HT+ YD I++YF Q P + YE + G +
Sbjct: 159 SETDTYEFRQQLAAKVFRHTASYDAMIANYFLSQ-TEEQYPESYTVTYEKVQDLRYGENP 217
Query: 668 QRQ 676
+Q
Sbjct: 218 HQQ 220
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 88.6 bits (210), Expect = 1e-16
Identities = 42/73 (57%), Positives = 55/73 (75%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SV DKTG+L LAK L G ++++SGGT L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 203 TLHPAVHAGILAR 241
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 88.2 bits (209), Expect = 2e-16
Identities = 41/74 (55%), Positives = 56/74 (75%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K A+LSVS+KTG++ AK+L++ +L ++GGT R L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 197 VKTLHPAVHAGILA 238
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 64.9 bits (151), Expect = 2e-09
Identities = 28/48 (58%), Positives = 38/48 (79%)
Frame = +1
Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
++ Q ++I +VV NLYPF QTV+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 87.8 bits (208), Expect = 2e-16
Identities = 41/72 (56%), Positives = 55/72 (76%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSV+DK+GL+ A L++ G++L+++GGT R L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 203 TLHPAVHAGILA 238
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 86.6 bits (205), Expect = 6e-16
Identities = 41/82 (50%), Positives = 58/82 (70%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 197 VKTLHPAVHAGILARLSDSARK 262
VKTLHP +H+GILA +A +
Sbjct: 77 VKTLHPFIHSGILADQRKAAHR 98
Score = 42.3 bits (95), Expect = 0.012
Identities = 24/65 (36%), Positives = 37/65 (56%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPS 435
+E + + + +VVCNLYPF TV+ + + VE IDIGG +++RA + S +
Sbjct: 98 REQIAQLGIQAFDLVVCNLYPFQDTVAS-GASFDECVEQIDIGGPSMVRAAAKNHP-SVA 155
Query: 436 SVTRP 450
VT P
Sbjct: 156 VVTSP 160
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 86.6 bits (205), Expect = 6e-16
Identities = 40/82 (48%), Positives = 59/82 (71%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDK+GL+ AK L++ G+++I++GGT + L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 197 VKTLHPAVHAGILARLSDSARK 262
VKTLHP VH G+L +S+ A K
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHK 86
Score = 59.3 bits (137), Expect = 1e-07
Identities = 25/50 (50%), Positives = 39/50 (78%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
++ M+ K I +VV NLYPF++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 86 KQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 86.6 bits (205), Expect = 6e-16
Identities = 42/73 (57%), Positives = 54/73 (73%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTG++ A+ L + G++L+++GGTA+ L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 203 TLHPAVHAGILAR 241
TLHP VH GIL R
Sbjct: 69 TLHPKVHGGILGR 81
Score = 63.3 bits (147), Expect = 6e-09
Identities = 29/47 (61%), Positives = 37/47 (78%)
Frame = +1
Query: 265 MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
M++ E I +VV NLYPF TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 89 MQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
Score = 35.1 bits (77), Expect = 1.8
Identities = 16/33 (48%), Positives = 22/33 (66%)
Frame = +2
Query: 482 EQTSSDDFGTRQRLALKAFTHTSDYDLAISDYF 580
+ +S F TR LA+KAF HT+ YD I++YF
Sbjct: 161 QHQNSLTFETRFDLAIKAFEHTAQYDSMIANYF 193
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 86.6 bits (205), Expect = 6e-16
Identities = 42/74 (56%), Positives = 56/74 (75%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SV DK G+L LAK L + +++I+SGGT + L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 197 VKTLHPAVHAGILA 238
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 41.9 bits (94), Expect = 0.016
Identities = 21/47 (44%), Positives = 31/47 (65%)
Frame = +1
Query: 265 MKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
++ ++ I VV NLYPF + V + D++ + VE IDIGG T+LRA
Sbjct: 87 LEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 86.6 bits (205), Expect = 6e-16
Identities = 38/76 (50%), Positives = 54/76 (71%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDK G++ K L G +++++GGT + L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 203 TLHPAVHAGILARLSD 250
TLHP +H GIL + SD
Sbjct: 63 TLHPKIHGGILHKRSD 78
Score = 38.7 bits (86), Expect = 0.15
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 6/118 (5%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIK-----ENKHHQTTLGQGRD*P*RRSLILRTMTSPYR- 572
KN+ V V+CDP DY+ V++ +K EN + + I M +
Sbjct: 133 KNYKDVMVLCDPLDYEKVIETLKKGQNDENFRLNLMIKAYEHTANYDAYIANYMNERFNG 192
Query: 573 TTSASNTSXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNAL 746
AS GQ +YG NPHQK A A+ + G F NL D AL
Sbjct: 193 GFGASKFIVGQKVFDTKYGENPHQKGALYEFDAFFSANFKALKGEASFNNLTDINAAL 250
Score = 35.1 bits (77), Expect = 1.8
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I +V NLYPF +T D + +ENIDIGG ++R+
Sbjct: 93 IDLVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 86.6 bits (205), Expect = 6e-16
Identities = 40/73 (54%), Positives = 56/73 (76%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
A++SV K G+ LAK+L E G +++++GGTA+ LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 203 TLHPAVHAGILAR 241
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/50 (46%), Positives = 34/50 (68%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+E++++ + I VVV NLYPF + + K +T D +E IDIGG TL+RA
Sbjct: 82 KEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRA 130
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 84.2 bits (199), Expect = 3e-15
Identities = 40/80 (50%), Positives = 59/80 (73%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDK L SL + L++ ++LI+SGGT + ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 197 VKTLHPAVHAGILARLSDSA 256
VKTLHP +HAGIL++ +D +
Sbjct: 72 VKTLHPKIHAGILSKRNDKS 91
Score = 43.6 bits (98), Expect = 0.005
Identities = 18/49 (36%), Positives = 33/49 (67%)
Frame = +1
Query: 259 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+++K +Y+ I +V+ N YPF +T+ + + +ENID+GG T++RA
Sbjct: 94 KELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRA 141
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 84.2 bits (199), Expect = 3e-15
Identities = 38/75 (50%), Positives = 54/75 (72%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDK G++ A+ L++ G ++I++GGT L AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 197 VKTLHPAVHAGILAR 241
VKTLHP +H G+LAR
Sbjct: 63 VKTLHPKIHGGLLAR 77
Score = 53.6 bits (123), Expect = 5e-06
Identities = 24/40 (60%), Positives = 32/40 (80%)
Frame = +1
Query: 286 MISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+I +VV NLYPF +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/44 (50%), Positives = 26/44 (59%)
Frame = +2
Query: 503 FGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYE 634
+ TRQRLA K F HT+ YD I+DYF KQ P L I Y+
Sbjct: 165 YATRQRLAAKVFRHTAAYDALIADYFTKQ-VGEDKPEKLTITYD 207
Score = 36.3 bits (80), Expect = 0.80
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 11/119 (9%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKE-NKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSAS 587
KNH VTVV DPADY V+ EI E + T + R + + + Y T
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAEQGETSYATRQRLAAKVFRHTAAYDALIADYFTKQVG 195
Query: 588 NTSXGQAQLT------LRYGMNPHQKP---AQVFTTRDSFADSRH*NGAP-GFINLCDA 734
+ +T +RYG NP Q T S A ++ NG F N+ DA
Sbjct: 196 EDKPEKLTITYDLNQPMRYGENPQQNADFYQNALPTAYSIAAAKQLNGKELSFNNIRDA 254
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 82.6 bits (195), Expect = 9e-15
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 197 VKTLHPAVHAGILAR 241
VKTLHP +HAG+LAR
Sbjct: 72 VKTLHPKIHAGLLAR 86
Score = 49.6 bits (113), Expect = 8e-05
Identities = 23/50 (46%), Positives = 35/50 (70%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
++ + + + I ++V NLYPFVQTVS + ++ AVE IDIGG ++LRA
Sbjct: 91 EKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRA 140
Score = 35.5 bits (78), Expect = 1.4
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 14/122 (11%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
KN VTVV DP DY +++EIK + H TTL + + L + T A
Sbjct: 143 KNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRKRLAQKTFEHLSYYDAHIATYLAEK 201
Query: 591 ----------TSXGQAQLTLRYGMNPHQKPAQVF---TTRDSFADSRH*NGAP-GFINLC 728
S + ++ LRYG NPHQ A S A+++ G P F NL
Sbjct: 202 EGATTLPARLPSIFKKKIDLRYGENPHQTAALYSIDPPLSHSLAEAQLLQGKPLSFNNLL 261
Query: 729 DA 734
D+
Sbjct: 262 DS 263
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.2 bits (194), Expect = 1e-14
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 203 TLHPAVHAGILAR 241
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
Score = 33.9 bits (74), Expect = 4.3
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = +2
Query: 494 SDDFGTRQRLALKAFTHTSDYDLAISDYFRKQ 589
S TR LA KAF + YD ISDYF+ Q
Sbjct: 166 SISLNTRLNLAAKAFKYIKQYDTMISDYFQHQ 197
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 82.2 bits (194), Expect = 1e-14
Identities = 36/74 (48%), Positives = 55/74 (74%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDKT L+ K L+E G+++I++GGT + L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 197 VKTLHPAVHAGILA 238
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
Score = 55.6 bits (128), Expect = 1e-06
Identities = 25/39 (64%), Positives = 31/39 (79%)
Frame = +1
Query: 289 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
I +VV NLYPF +T+SK DVT +A+ENIDIGG +LRA
Sbjct: 96 IDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P---*RRSLILRTMTSPYRTTS 581
KNH VTV+ DPADY V+ +IKE +L + R+ R + + + Y T
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTAAYDALIADYLTNV 194
Query: 582 ASNTSXGQAQLT------LRYGMNPHQK 647
Q +T LRYG NPHQ+
Sbjct: 195 VGEKEPEQFTVTFEKKQSLRYGENPHQE 222
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 81.0 bits (191), Expect = 3e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 197 VKTLHPAVHAGILA 238
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
Score = 41.5 bits (93), Expect = 0.021
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = +1
Query: 283 EMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTT 423
+ +VV NLYPF + + +D +E IDIGG L+RA + T
Sbjct: 98 DAFDLVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHT 144
Score = 35.5 bits (78), Expect = 1.4
Identities = 13/28 (46%), Positives = 23/28 (82%)
Frame = +2
Query: 512 RQRLALKAFTHTSDYDLAISDYFRKQYF 595
R +LA+KA++HTS+YDL IS + ++++
Sbjct: 171 RHQLAIKAYSHTSEYDLHISRWLSERFY 198
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 80.2 bits (189), Expect = 5e-14
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K ALLSV DKTG++ LA++L + +++SGGT L AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 197 VKTLHPAVHAGILAR 241
VKTLHP VH G+L R
Sbjct: 92 VKTLHPKVHGGLLGR 106
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 77.0 bits (181), Expect = 5e-13
Identities = 36/76 (47%), Positives = 54/76 (71%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SV K G+ LA++ + G +++++G TA+ L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 203 TLHPAVHAGILARLSD 250
TLHP +HAGILA +++
Sbjct: 71 TLHPYIHAGILADMTN 86
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +1
Query: 295 VVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 402
+VV NLYPF TV + AD +E IDIGG +++R
Sbjct: 103 LVVVNLYPFADTV-RSGANEADTIEKIDIGGPSMVR 137
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 75.8 bits (178), Expect = 1e-12
Identities = 36/74 (48%), Positives = 51/74 (68%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
+ AL+SVSDKTG+ SLAK+L + ++LI + GT + L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 197 VKTLHPAVHAGILA 238
VKTLHP +H GIL+
Sbjct: 69 VKTLHPKIHGGILS 82
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/46 (39%), Positives = 29/46 (63%)
Frame = +1
Query: 268 KRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
K + I +V+ N YPF + V K ++ + + ++NIDIGGV L R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 74.1 bits (174), Expect = 3e-12
Identities = 38/72 (52%), Positives = 51/72 (70%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SVSDK+ L LA+ L ++++++GGT R L G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 203 TLHPAVHAGILA 238
TLHP +H GILA
Sbjct: 77 TLHPKIHGGILA 88
Score = 56.8 bits (131), Expect = 5e-07
Identities = 24/50 (48%), Positives = 36/50 (72%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
Q +++ I +V+ NLYPF +T++KP + ADA+ENIDIGG T++RA
Sbjct: 95 QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRA 144
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 73.3 bits (172), Expect = 6e-12
Identities = 34/73 (46%), Positives = 47/73 (64%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 203 TLHPAVHAGILAR 241
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 38.3 bits (85), Expect = 0.20
Identities = 17/39 (43%), Positives = 27/39 (69%)
Frame = +1
Query: 286 MISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 402
+I +V+ +LYPF TV+ + D +E IDIGG++L+R
Sbjct: 100 LIDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIR 137
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 70.5 bits (165), Expect = 4e-11
Identities = 38/76 (50%), Positives = 50/76 (65%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
ALLSVSDKTGLL LAK+L+ ++LIASGGTA+ L AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 203 TLHPAVHAGILARLSD 250
T+ + + +L R D
Sbjct: 67 TISFEIASSLLFRRQD 82
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/92 (34%), Positives = 45/92 (48%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
KN VTV+CDP+ Y +KE N ++ +T + R + + + TMT+ Y A
Sbjct: 137 KNFHSVTVLCDPSQYSEFLKEF--NGNNGSTTWEFRQ---KCAAAVYTMTAFYDMAIAGF 191
Query: 591 TSXGQAQLTLRYGMNPHQKPAQVFTTRDSFAD 686
+ LRYG NPHQK +D FAD
Sbjct: 192 LTQNSG-AALRYGENPHQK---AVVLKDPFAD 219
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/41 (56%), Positives = 27/41 (65%)
Frame = +1
Query: 283 EMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
E I +VV NLYPF T+ K + +ENIDIGG TLLRA
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRA 134
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 69.3 bits (162), Expect = 9e-11
Identities = 37/74 (50%), Positives = 49/74 (66%)
Frame = +2
Query: 20 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 199
LA+L+VSDK + LA L G ++A+ GT R LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 200 KTLHPAVHAGILAR 241
KTL ++ GILAR
Sbjct: 62 KTLTVSLMGGILAR 75
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/75 (44%), Positives = 47/75 (62%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K AL+SV K GL + L E G++ +++GGT + + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 197 VKTLHPAVHAGILAR 241
VKTLHP + GIL R
Sbjct: 68 VKTLHPKIFGGILCR 82
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/59 (42%), Positives = 40/59 (67%), Gaps = 7/59 (11%)
Frame = +1
Query: 250 LCQEDMKR-----QKYEM--ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
LC+ D+++ +KYE+ I +V+ +LYPF TV+ + AD +E IDIGG++L+RA
Sbjct: 80 LCRRDLEQDIQQIEKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRA 137
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 67.3 bits (157), Expect = 4e-10
Identities = 34/79 (43%), Positives = 47/79 (59%)
Frame = +2
Query: 5 ASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEM 184
AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 185 LGGRVKTLHPAVHAGILAR 241
L G VKTLHP + GIL R
Sbjct: 78 LDGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 67.3 bits (157), Expect = 4e-10
Identities = 34/79 (43%), Positives = 47/79 (59%)
Frame = +2
Query: 5 ASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEM 184
AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T P++
Sbjct: 18 ASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKI 77
Query: 185 LGGRVKTLHPAVHAGILAR 241
L G VKTLHP + GIL R
Sbjct: 78 LDGHVKTLHPNIQGGILPR 96
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/73 (45%), Positives = 46/73 (63%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K L+S+ +K L + + L E G ++ AS GTA+ L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 197 VKTLHPAVHAGIL 235
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 64.5 bits (150), Expect = 3e-09
Identities = 33/80 (41%), Positives = 50/80 (62%)
Frame = +2
Query: 11 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 190
N K A++SV DKT L LA L G+++I + GT + L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 191 GRVKTLHPAVHAGILARLSD 250
GRVK++ P + GILA+ +D
Sbjct: 62 GRVKSIDPKLAGGILAKSND 81
Score = 36.7 bits (81), Expect = 0.61
Identities = 20/50 (40%), Positives = 29/50 (58%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+EDM + I +VV N +P + ++K +ENIDIGG +LLRA
Sbjct: 85 EEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLLENIDIGGYSLLRA 133
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 64.1 bits (149), Expect = 3e-09
Identities = 29/75 (38%), Positives = 48/75 (64%)
Frame = +2
Query: 17 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 196
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 197 VKTLHPAVHAGILAR 241
+KTLH ++A ILA+
Sbjct: 68 IKTLHHKIYASILAQ 82
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 3/60 (5%)
Frame = +1
Query: 235 SSIIRLCQEDMKR-QKYEMI--SVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+SI+ + D K +KY +I +VV N YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 77 ASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 62.9 bits (146), Expect = 8e-09
Identities = 33/77 (42%), Positives = 51/77 (66%)
Frame = +2
Query: 26 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 205
L+SVSD +GL L + L+ + A+ GT + L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 206 LHPAVHAGILARLSDSA 256
LHPAV +GIL+R + +
Sbjct: 61 LHPAVFSGILSRRDEQS 77
Score = 49.6 bits (113), Expect = 8e-05
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +1
Query: 256 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
+ D+KR Y +V+CNLY F + K ++ D +ENIDIGG++L+RA
Sbjct: 78 EADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 56.0 bits (129), Expect = 9e-07
Identities = 28/48 (58%), Positives = 33/48 (68%)
Frame = +1
Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 405
DMKR I +VV NLYPF QTV++PDVT A NIDIGG ++RA
Sbjct: 106 DMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRA 153
Score = 40.3 bits (90), Expect = 0.049
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 7/77 (9%)
Frame = +2
Query: 26 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTARXLRN-----AGLTVQDVSDITRAPEM 184
L+SVSDKTGL L + + ++GGT + + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 185 LGGRVKTLHPAVHAGIL 235
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
Score = 37.9 bits (84), Expect = 0.26
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +2
Query: 509 TRQRLALKAFTHTSDYDLAISDYFRKQ 589
TR LA KAF HT+ YD AI+DY +KQ
Sbjct: 188 TRFELAQKAFDHTAAYDRAIADYLKKQ 214
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +2
Query: 26 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 205
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 206 LHPAVHAGILA 238
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -1
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTD 301
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 41.5 bits (93), Expect = 0.021
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = -1
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHHAYHLVLLTFHV 262
A+ G AAD+DVLD + HG V R ERV+V HH L + H+
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHHVDGLDAVLLHL 458
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.5 bits (88), Expect = 0.086
Identities = 24/67 (35%), Positives = 34/67 (50%)
Frame = -3
Query: 226 SMYRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKRPGGTATGNQLQATFRQALC*RE*TR 47
+M+ + P H R + DV H+L+ +A + R GG A G QL A RQ + T
Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTG 539
Query: 46 LV*NAEK 26
LV N E+
Sbjct: 540 LVGNGEE 546
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 39.1 bits (87), Expect = 0.11
Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 8/100 (8%)
Frame = +1
Query: 73 PVGMWPAVDCQWRYRQXASE-----RRPHSSRC--VGHHESTGDARRSGEN-FTSSGTCW 228
P WP CQ ++R S R P + VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 229 DLSSIIRLCQEDMKRQKYEMISVVVCNLYPFVQTVSKPDV 348
D S + R Q+ K+ E SV V N + VSKP +
Sbjct: 247 DSSPLHREVQQ-RKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 38.3 bits (85), Expect = 0.20
Identities = 16/43 (37%), Positives = 31/43 (72%)
Frame = +2
Query: 38 SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI 166
SDK ++ K+L++ G++L+A+ GTAR L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:
IMP cyclohydrolase - Geobacter sp. FRC-32
Length = 388
Score = 37.1 bits (82), Expect = 0.46
Identities = 18/45 (40%), Positives = 26/45 (57%)
Frame = +3
Query: 609 QLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
++ L+YG N HQ PA + +S + NG P +IN+ DAL A
Sbjct: 2 EIKLKYGCNSHQTPANLIIPENS--GFQVLNGTPSYINILDALGA 44
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 36.7 bits (81), Expect = 0.61
Identities = 22/72 (30%), Positives = 34/72 (47%)
Frame = +2
Query: 41 DKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAV 220
DK + LA+ G +L+A+ GTA AG+T V + P L +++ H V
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIV 1007
Query: 221 HAGILARLSDSA 256
+ LSD+A
Sbjct: 1008 MVVNITNLSDAA 1019
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 36.7 bits (81), Expect = 0.61
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +2
Query: 41 DKTGLLSLAKSLSECGLQLIASGGTARXLRN 133
DK GL+ +A+SL E G +L A+ GTAR LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 36.3 bits (80), Expect = 0.80
Identities = 22/36 (61%), Positives = 23/36 (63%)
Frame = -1
Query: 402 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH 295
AQ G AADVDVLD V L +RL ERVQV HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 1.1
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +2
Query: 182 MLGGRVKTLHPAVHAGILAR 241
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.1 bits (77), Expect = 1.8
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +2
Query: 23 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGL 142
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.1 bits (77), Expect = 1.8
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +2
Query: 26 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI-TRAPEML 187
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 33.9 bits (74), Expect = 4.3
Identities = 23/51 (45%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +2
Query: 11 NGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDV 157
+GK ALLS+ DK LL +AK L G + A+ GTA+ L+ AG+ Q V
Sbjct: 74 SGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 33.5 bits (73), Expect = 5.6
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Frame = +2
Query: 2 VASNGKLAL-LSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI 166
V S+G + L + DK ++LAK G QL+A+ GTA L GL V V I
Sbjct: 932 VPSHGNVLLTVRDEDKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene
pglZ; n=2; Streptomyces coelicolor|Rep: Bacteriophage
(PhiC31) resistance gene pglZ - Streptomyces coelicolor
Length = 974
Score = 33.1 bits (72), Expect = 7.5
Identities = 16/49 (32%), Positives = 23/49 (46%)
Frame = +1
Query: 58 LVSKEPVGMWPAVDCQWRYRQXASERRPHSSRCVGHHESTGDARRSGEN 204
L+ P G WPAV W RQ A +G +++ G RR G++
Sbjct: 151 LLDATPPGSWPAVPGGWLSRQYALTALAQRRLRLGRYDTEGGPRRPGDD 199
>UniRef50_UPI0000498755 Cluster: cullin; n=1; Entamoeba histolytica
HM-1:IMSS|Rep: cullin - Entamoeba histolytica HM-1:IMSS
Length = 672
Score = 32.7 bits (71), Expect = 9.9
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +1
Query: 145 SSRCVGHHESTG-DARRSGENFTSSGTCWDLSSIIRLCQEDMKRQKYEMISVVVCNLYPF 321
SS GHH+ G +++ E + W + +RL ++ K ++ ++I++V+ PF
Sbjct: 580 SSFLQGHHKKLGITEQKTSEKIKEDRSAWGEAVCVRLMKKMKKCRELDLINMVIKEKAPF 639
Query: 322 VQT 330
+ T
Sbjct: 640 IPT 642
>UniRef50_Q0R568 Cluster: Putative minor structural protein; n=3;
root|Rep: Putative minor structural protein -
Streptococcus phage MM1 1998
Length = 504
Score = 32.7 bits (71), Expect = 9.9
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +3
Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQ--TTLGQGRD*P 527
+N DRV V D + YD ++ EIK+ K + TLG RD P
Sbjct: 372 RNDDRVQVFFDGSHYDFIIPEIKDKKSAKIHITLGALRDWP 412
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 719,944,419
Number of Sequences: 1657284
Number of extensions: 14244925
Number of successful extensions: 44579
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 42597
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44545
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61323318355
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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