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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbpv0648
         (747 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D89976-1|BAA21762.1|  592|Homo sapiens 5-aminoimidazole-4-carbox...   115   2e-25
D82348-1|BAA11559.1|  592|Homo sapiens 5-aminoimidazole-4-carbox...   115   2e-25
BC008879-1|AAH08879.1|  592|Homo sapiens 5-aminoimidazole-4-carb...   115   2e-25
AC073284-1|AAY24062.1|  592|Homo sapiens unknown protein.             115   2e-25
AB062403-1|BAB93490.1|  592|Homo sapiens 5-aminoimidazole-4-carb...   115   2e-25
U37436-1|AAA97405.1|  591|Homo sapiens AICAR formyltransferase/I...   111   3e-24

>D89976-1|BAA21762.1|  592|Homo sapiens
           5-aminoimidazole-4-carboxamide ribonucleotide
           transformylase protein.
          Length = 592

 Score =  115 bits (277), Expect = 2e-25
 Identities = 55/76 (72%), Positives = 66/76 (86%)
 Frame = +2

Query: 14  GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
           G+LAL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGG
Sbjct: 4   GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63

Query: 194 RVKTLHPAVHAGILAR 241
           RVKTLHPAVHAGILAR
Sbjct: 64  RVKTLHPAVHAGILAR 79



 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 87  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212


>D82348-1|BAA11559.1|  592|Homo sapiens
           5-aminoimidazole-4-carboxamide-1-beta-D-ribonucl eotide
           transformylase/inosinic protein.
          Length = 592

 Score =  115 bits (277), Expect = 2e-25
 Identities = 55/76 (72%), Positives = 66/76 (86%)
 Frame = +2

Query: 14  GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
           G+LAL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGG
Sbjct: 4   GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63

Query: 194 RVKTLHPAVHAGILAR 241
           RVKTLHPAVHAGILAR
Sbjct: 64  RVKTLHPAVHAGILAR 79



 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 87  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212


>BC008879-1|AAH08879.1|  592|Homo sapiens
           5-aminoimidazole-4-carboxamide ribonucleotide
           formyltransferase/IMP cyclohydrol protein.
          Length = 592

 Score =  115 bits (277), Expect = 2e-25
 Identities = 55/76 (72%), Positives = 66/76 (86%)
 Frame = +2

Query: 14  GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
           G+LAL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGG
Sbjct: 4   GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63

Query: 194 RVKTLHPAVHAGILAR 241
           RVKTLHPAVHAGILAR
Sbjct: 64  RVKTLHPAVHAGILAR 79



 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 87  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212


>AC073284-1|AAY24062.1|  592|Homo sapiens unknown protein.
          Length = 592

 Score =  115 bits (277), Expect = 2e-25
 Identities = 55/76 (72%), Positives = 66/76 (86%)
 Frame = +2

Query: 14  GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
           G+LAL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGG
Sbjct: 4   GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63

Query: 194 RVKTLHPAVHAGILAR 241
           RVKTLHPAVHAGILAR
Sbjct: 64  RVKTLHPAVHAGILAR 79



 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 87  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212


>AB062403-1|BAB93490.1|  592|Homo sapiens
           5-aminoimidazole-4-carboxamide-1-bata-D-ribonucl eotid
           transformylase/inosinica protein.
          Length = 592

 Score =  115 bits (277), Expect = 2e-25
 Identities = 55/76 (72%), Positives = 66/76 (86%)
 Frame = +2

Query: 14  GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 193
           G+LAL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGG
Sbjct: 4   GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63

Query: 194 RVKTLHPAVHAGILAR 241
           RVKTLHPAVHAGILAR
Sbjct: 64  RVKTLHPAVHAGILAR 79



 Score = 89.0 bits (211), Expect = 2e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLET------RRQLALKAFTHTAQYDEAIS 190

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 191 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 246



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 87  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 146

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 147 EPEDYVVVSTEMQSSESKDTSLETR 171



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 212


>U37436-1|AAA97405.1|  591|Homo sapiens AICAR formyltransferase/IMP
           cyclohydrolase bifunctional enzyme protein.
          Length = 591

 Score =  111 bits (266), Expect = 3e-24
 Identities = 53/73 (72%), Positives = 63/73 (86%)
 Frame = +2

Query: 23  ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 202
           AL SVSDKTGL+  A++L+  GL L+ASGGTA+ LR+AGL V+DVS++T  PEMLGGRVK
Sbjct: 6   ALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVK 65

Query: 203 TLHPAVHAGILAR 241
           TLHPAVHAGILAR
Sbjct: 66  TLHPAVHAGILAR 78



 Score = 88.2 bits (209), Expect = 3e-17
 Identities = 53/117 (45%), Positives = 68/117 (58%), Gaps = 6/117 (5%)
 Frame = +3

Query: 411 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGQGRD*P*RRSLILRTMTSPYRTTSASN 590
           KNH RVTVVC+P DY  V  E++ ++   T+L        RR L L+  T   +   A +
Sbjct: 136 KNHARVTVVCEPEDYVVVSTEMQSSESKGTSLET------RRQLALKAFTHTAQYDEAIS 189

Query: 591 T------SXGQAQLTLRYGMNPHQKPAQVFTTRDSFADSRH*NGAPGFINLCDALNA 743
                  S G +Q+ LRYGMNPHQ PAQ++T +     +   NGAPGFINLCDALNA
Sbjct: 190 DYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVL-NGAPGFINLCDALNA 245



 Score = 74.1 bits (174), Expect = 5e-13
 Identities = 41/85 (48%), Positives = 52/85 (61%), Gaps = 5/85 (5%)
 Frame = +1

Query: 262 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 426
           DM R  + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA  +     T   
Sbjct: 86  DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVC 145

Query: 427 SPSSVTRPTTML*SKKSKRTNIIRR 501
            P      +T + S +SK T++  R
Sbjct: 146 EPEDYVVVSTEMQSSESKGTSLETR 170



 Score = 56.8 bits (131), Expect = 8e-08
 Identities = 28/58 (48%), Positives = 34/58 (58%)
 Frame = +2

Query: 464 SQRNQREQTSSDDFGTRQRLALKAFTHTSDYDLAISDYFRKQYFARASPTDLKIRYEP 637
           S   Q  ++      TR++LALKAFTHT+ YD AISDYFRKQY    S   L+    P
Sbjct: 154 STEMQSSESKGTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNP 211


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,829,535
Number of Sequences: 237096
Number of extensions: 2158993
Number of successful extensions: 10618
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 10306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10606
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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