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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbpv0636
         (801 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M55150-1|AAA52422.1|  419|Homo sapiens fumarylacetoacetate hydro...   103   6e-22
BT007160-1|AAP35824.1|  419|Homo sapiens fumarylacetoacetate hyd...   103   6e-22
BC002527-1|AAH02527.1|  419|Homo sapiens fumarylacetoacetate hyd...   103   6e-22
X51728-1|CAA36016.1|  349|Homo sapiens protein ( Human mRNA for ...    81   6e-15
BX537608-1|CAD97795.1|  349|Homo sapiens hypothetical protein pr...    81   6e-15
AL096773-5|CAI18825.1|  798|Homo sapiens cold shock domain conta...    31   3.7  
AB020692-1|BAA74908.2|  826|Homo sapiens KIAA0885 protein protein.     31   3.7  

>M55150-1|AAA52422.1|  419|Homo sapiens fumarylacetoacetate
           hydrolase protein.
          Length = 419

 Score =  103 bits (248), Expect = 6e-22
 Identities = 67/166 (40%), Positives = 87/166 (52%), Gaps = 4/166 (2%)
 Frame = +1

Query: 253 LDLNIISRLFDGPLLKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNA 432
           LDL+II  LF GP+L   Q+VF +  LN+FM L +  W EAR  LQ LL VS   L+++ 
Sbjct: 41  LDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDT 100

Query: 433 ELREKAFVKQTDVQMHVPVEVGDYT--ASIRRCSTLPT*A*CSGER--RPLCSRTGNIYR 600
           ELR+ AF+ Q    MH+P  +GDYT   S R+ +T         E    P        Y 
Sbjct: 101 ELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYH 160

Query: 601 WVIMDVPVL**SLGTPIHRPYGQTLPVEXAAPHFGPCRLMDFELEV 738
                V V     GTPI RP GQ  P +   P +G C+L+D ELE+
Sbjct: 161 GRASSVVV----SGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEM 202



 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 35/44 (79%), Positives = 38/44 (86%)
 Frame = +3

Query: 510 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISG 641
           FYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SG
Sbjct: 127 FYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSG 170



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 23/39 (58%), Positives = 29/39 (74%)
 Frame = +2

Query: 137 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWI 253
           SFI  + DSDFPI NLPYGVF++  + +  IGVAIG+ I
Sbjct: 2   SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQI 40


>BT007160-1|AAP35824.1|  419|Homo sapiens fumarylacetoacetate
           hydrolase (fumarylacetoacetase) protein.
          Length = 419

 Score =  103 bits (248), Expect = 6e-22
 Identities = 67/166 (40%), Positives = 87/166 (52%), Gaps = 4/166 (2%)
 Frame = +1

Query: 253 LDLNIISRLFDGPLLKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNA 432
           LDL+II  LF GP+L   Q+VF +  LN+FM L +  W EAR  LQ LL VS   L+++ 
Sbjct: 41  LDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDT 100

Query: 433 ELREKAFVKQTDVQMHVPVEVGDYT--ASIRRCSTLPT*A*CSGER--RPLCSRTGNIYR 600
           ELR+ AF+ Q    MH+P  +GDYT   S R+ +T         E    P        Y 
Sbjct: 101 ELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYH 160

Query: 601 WVIMDVPVL**SLGTPIHRPYGQTLPVEXAAPHFGPCRLMDFELEV 738
                V V     GTPI RP GQ  P +   P +G C+L+D ELE+
Sbjct: 161 GRASSVVV----SGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEM 202



 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 35/44 (79%), Positives = 38/44 (86%)
 Frame = +3

Query: 510 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISG 641
           FYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SG
Sbjct: 127 FYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSG 170



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 23/39 (58%), Positives = 29/39 (74%)
 Frame = +2

Query: 137 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWI 253
           SFI  + DSDFPI NLPYGVF++  + +  IGVAIG+ I
Sbjct: 2   SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQI 40


>BC002527-1|AAH02527.1|  419|Homo sapiens fumarylacetoacetate
           hydrolase (fumarylacetoacetase) protein.
          Length = 419

 Score =  103 bits (248), Expect = 6e-22
 Identities = 67/166 (40%), Positives = 87/166 (52%), Gaps = 4/166 (2%)
 Frame = +1

Query: 253 LDLNIISRLFDGPLLKSKQNVFKEEKLNAFMALTKPHWIEARETLQKLLDVSSPALQNNA 432
           LDL+II  LF GP+L   Q+VF +  LN+FM L +  W EAR  LQ LL VS   L+++ 
Sbjct: 41  LDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDT 100

Query: 433 ELREKAFVKQTDVQMHVPVEVGDYT--ASIRRCSTLPT*A*CSGER--RPLCSRTGNIYR 600
           ELR+ AF+ Q    MH+P  +GDYT   S R+ +T         E    P        Y 
Sbjct: 101 ELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYH 160

Query: 601 WVIMDVPVL**SLGTPIHRPYGQTLPVEXAAPHFGPCRLMDFELEV 738
                V V     GTPI RP GQ  P +   P +G C+L+D ELE+
Sbjct: 161 GRASSVVV----SGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEM 202



 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 35/44 (79%), Positives = 38/44 (86%)
 Frame = +3

Query: 510 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISG 641
           FYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SG
Sbjct: 127 FYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSG 170



 Score = 50.8 bits (116), Expect = 6e-06
 Identities = 23/39 (58%), Positives = 29/39 (74%)
 Frame = +2

Query: 137 SFIEYSSDSDFPIENLPYGVFTSDKNAQKHIGVAIGEWI 253
           SFI  + DSDFPI NLPYGVF++  + +  IGVAIG+ I
Sbjct: 2   SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQI 40


>X51728-1|CAA36016.1|  349|Homo sapiens protein ( Human mRNA for
           fumarylacetoacetase (EC 3.7.1.2). ).
          Length = 349

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 35/44 (79%), Positives = 38/44 (86%)
 Frame = +3

Query: 510 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISG 641
           FYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SG
Sbjct: 57  FYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSG 100



 Score = 70.9 bits (166), Expect = 5e-12
 Identities = 51/136 (37%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
 Frame = +1

Query: 343 MALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYT--ASI 516
           M L +  W EAR  LQ LL VS   L+++ ELR+ AF+ Q    MH+P  +GDYT   S 
Sbjct: 1   MGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSS 60

Query: 517 RRCSTLPT*A*CSGER--RPLCSRTGNIYRWVIMDVPVL**SLGTPIHRPYGQTLPVEXA 690
           R+ +T         E    P        Y      V V     GTPI RP GQ  P +  
Sbjct: 61  RQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVV----SGTPIRRPMGQMKPDDSK 116

Query: 691 APHFGPCRLMDFELEV 738
            P +G C+L+D ELE+
Sbjct: 117 PPVYGACKLLDMELEM 132


>BX537608-1|CAD97795.1|  349|Homo sapiens hypothetical protein
           protein.
          Length = 349

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 35/44 (79%), Positives = 38/44 (86%)
 Frame = +3

Query: 510 FYSSLQHATNVGIMFRGKEAALFENWKHLPVGYHGRSSSIVISG 641
           FYSS QHATNVGIMFR KE AL  NW HLPVGYHGR+SS+V+SG
Sbjct: 57  FYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSG 100



 Score = 70.9 bits (166), Expect = 5e-12
 Identities = 51/136 (37%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
 Frame = +1

Query: 343 MALTKPHWIEARETLQKLLDVSSPALQNNAELREKAFVKQTDVQMHVPVEVGDYT--ASI 516
           M L +  W EAR  LQ LL VS   L+++ ELR+ AF+ Q    MH+P  +GDYT   S 
Sbjct: 1   MGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSS 60

Query: 517 RRCSTLPT*A*CSGER--RPLCSRTGNIYRWVIMDVPVL**SLGTPIHRPYGQTLPVEXA 690
           R+ +T         E    P        Y      V V     GTPI RP GQ  P +  
Sbjct: 61  RQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVV----SGTPIRRPMGQMKPDDSK 116

Query: 691 APHFGPCRLMDFELEV 738
            P +G C+L+D ELE+
Sbjct: 117 PPVYGACKLLDMELEM 132


>AL096773-5|CAI18825.1|  798|Homo sapiens cold shock domain
           containing E1, RNA-binding protein.
          Length = 798

 Score = 31.5 bits (68), Expect = 3.7
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = +1

Query: 292 LLKSKQNVFKEEKLNAFMALTKPHWIEARE-TLQKLLDVSSPALQNNAELREKAFVKQTD 468
           L+K KQ +  EE++N  +    PH +E++           S   + N E+    +  + D
Sbjct: 87  LVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPE-D 145

Query: 469 VQMHVPVEVGD 501
           V+ +V +E GD
Sbjct: 146 VEGNVQLETGD 156


>AB020692-1|BAA74908.2|  826|Homo sapiens KIAA0885 protein protein.
          Length = 826

 Score = 31.5 bits (68), Expect = 3.7
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
 Frame = +1

Query: 292 LLKSKQNVFKEEKLNAFMALTKPHWIEARE-TLQKLLDVSSPALQNNAELREKAFVKQTD 468
           L+K KQ +  EE++N  +    PH +E++           S   + N E+    +  + D
Sbjct: 115 LVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPE-D 173

Query: 469 VQMHVPVEVGD 501
           V+ +V +E GD
Sbjct: 174 VEGNVQLETGD 184


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,821,556
Number of Sequences: 237096
Number of extensions: 2540125
Number of successful extensions: 5096
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4917
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5096
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9869080686
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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