Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0613
(858 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 115 1e-24
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 109 7e-23
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 99 7e-20
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 100 9e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 1e-19
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 2e-19
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 97 5e-19
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 96 9e-19
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 95 2e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 95 2e-18
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 95 3e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 3e-18
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 6e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 93 8e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 1e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 2e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 91 3e-17
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 3e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 90 6e-17
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 89 2e-16
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 89 2e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 88 2e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 88 3e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 88 3e-16
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 87 7e-16
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 87 7e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 86 9e-16
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 84 4e-15
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 84 4e-15
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 84 5e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 1e-14
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 2e-14
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 82 2e-14
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 82 2e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 4e-14
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 80 6e-14
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 77 8e-13
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 76 1e-12
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 74 4e-12
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 7e-12
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 1e-10
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 69 1e-10
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 69 1e-10
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 69 2e-10
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 69 2e-10
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 65 2e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 64 4e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 57 7e-07
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 48 2e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 43 0.009
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 42 0.015
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.080
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 39 0.14
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 38 0.25
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 38 0.32
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 37 0.75
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 36 0.99
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 1.3
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 35 2.3
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 35 2.3
UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene ... 33 9.2
UniRef50_A2R5D4 Cluster: Contig An15c0130, complete genome; n=8;... 33 9.2
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 115 bits (277), Expect = 1e-24
Identities = 55/76 (72%), Positives = 66/76 (86%)
Frame = +3
Query: 21 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 200
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA+ LR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 201 RVKTLHPAVHAGILAR 248
RVKTLHPAVHAGILAR
Sbjct: 64 RVKTLHPAVHAGILAR 79
Score = 97.5 bits (232), Expect = 4e-19
Identities = 79/213 (37%), Positives = 104/213 (48%), Gaps = 12/213 (5%)
Frame = +2
Query: 239 LSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXP 418
L+ I D DM R + +I VV CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA
Sbjct: 77 LARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAA 136
Query: 419 R-----TTTGSPSSVTRPTTML*SKKSKRTNI-------IRRFGHKAEISPEGVHSYFGL 562
+ T P +T + S +SK T++ ++ F H A+ E + YF
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYD-EAISDYF-- 193
Query: 563 *PRHIGLLSASNTRXGXAQLTLRYGMNPHQKXGPGFSRPETVCRFTXTERCAWIYQLVXR 742
G +Q+ LRYGMNPHQ ++ + T L
Sbjct: 194 ---------RKQYSKGVSQMPLRYGMNPHQTPAQLYTL-QPKLPITVLNGAPGFINLCD- 242
Query: 743 A*NAWQLVKGA*RXALXLPCXRLSFQATLSPAG 841
A NAWQLVK + AL +P SF+ +SPAG
Sbjct: 243 ALNAWQLVKEL-KEALGIPA-AASFK-HVSPAG 272
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 109 bits (263), Expect = 7e-23
Identities = 54/75 (72%), Positives = 62/75 (82%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ AK L + GL L+ASGGTA+ LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 210 TLHPAVHAGILARLS 254
TLHPAVH GILAR S
Sbjct: 61 TLHPAVHGGILARKS 75
Score = 79.0 bits (186), Expect = 1e-13
Identities = 37/52 (71%), Positives = 42/52 (80%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+D DM++ Y +I VVVCNLYPFV+TVS P VTV DAVE IDIGGVTLLRA
Sbjct: 77 ADTADMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
Score = 47.6 bits (108), Expect = 4e-04
Identities = 36/93 (38%), Positives = 48/93 (51%)
Frame = +1
Query: 418 KNHDRVTVVCDPADYDAVVKEIKENKHHQTIWAQGRD*P*RRSLILRTMTSPYRTTFRKQ 597
KNH RVTVVCDPADY V +E++ + RD P R L + T PYRTT
Sbjct: 131 KNHARVTVVCDPADYPRVAEEME--------GSGSRDTPSRTRL---STTRPYRTT-SGD 178
Query: 598 YSXGASPTDLKIRYEPTSEAGPRFFTTRDSLPI 696
S A P+ L + +A + +T R +LP+
Sbjct: 179 SSAVAFPSCLCVYGMNPHQAPAQLYTLRPALPL 211
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 99 bits (238), Expect = 7e-20
Identities = 51/76 (67%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
LALLSVSDKTGL+ LA++L E G QL++SGGTA+ L AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 204 VKTLHPAVHAGILARL 251
VKTLHP +H GILARL
Sbjct: 69 VKTLHPRIHGGILARL 84
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----T 424
D+ D++ I +VV N YPF QTV++ V++ +A E IDIGG TL RA + T
Sbjct: 89 DRADLEALGIPPIQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARAAAKNYPHVT 148
Query: 425 TTGSPSSVTRPTTML*SKKSKRTNIIRRF 511
PS + +L S S+ + RF
Sbjct: 149 VLTDPSQYPQYLQLLSSPSSEAERLAFRF 177
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 99.5 bits (237), Expect = 9e-20
Identities = 52/76 (68%), Positives = 60/76 (78%), Gaps = 1/76 (1%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
LALLSVSDKTGL+ LA+SL E G QL++SGGTA+ L AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 204 VKTLHPAVHAGILARL 251
VKTLHP +H GILARL
Sbjct: 77 VKTLHPRIHGGILARL 92
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/51 (47%), Positives = 33/51 (64%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
D+ D++ I +VV N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 97 DRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 99.1 bits (236), Expect = 1e-19
Identities = 46/72 (63%), Positives = 60/72 (83%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ A+SL+ G++LI++GGTA+ + +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 210 TLHPAVHAGILA 245
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 43.6 bits (98), Expect = 0.007
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
E MK I ++V NLYPF TV + +D +ENIDIGG ++RA
Sbjct: 91 EAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 98.7 bits (235), Expect = 2e-19
Identities = 46/72 (63%), Positives = 59/72 (81%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL A +LS+ G++L+++GGT R L AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 210 TLHPAVHAGILA 245
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
Score = 39.9 bits (89), Expect = 0.080
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 296 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
I ++V NLYPF +T+ K D VENID+GG ++RA
Sbjct: 150 IDLLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRA 187
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 97.1 bits (231), Expect = 5e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ LA++L ++L+++GGTA +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 210 TLHPAVHAGILAR 248
TLHP VH G+L R
Sbjct: 71 TLHPMVHGGLLGR 83
Score = 50.0 bits (114), Expect = 8e-05
Identities = 23/51 (45%), Positives = 32/51 (62%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
D M + I +++ NLYPF Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 87 DDAVMAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 96.3 bits (229), Expect = 9e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDK G++ A++LS+ G++L+++GGTAR L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 210 TLHPAVHAGILAR 248
TLHP VH GIL R
Sbjct: 70 TLHPKVHGGILGR 82
Score = 60.5 bits (140), Expect = 5e-08
Identities = 27/51 (52%), Positives = 37/51 (72%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
D M + + I +VV NLYPF QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 86 DDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
Score = 33.1 bits (72), Expect = 9.2
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 516 TRQRLALKAFTHTSDYDLAISDYF 587
TR LA+KAF HT+ YD I++YF
Sbjct: 171 TRFNLAIKAFEHTAAYDSMIANYF 194
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 95.5 bits (227), Expect = 2e-18
Identities = 48/76 (63%), Positives = 60/76 (78%), Gaps = 1/76 (1%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 200
+LALLSVSDK+G++ LA+ L +E LI+SGGTA+ L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 201 RVKTLHPAVHAGILAR 248
RVKTLHP +H GILAR
Sbjct: 63 RVKTLHPRIHGGILAR 78
Score = 67.3 bits (157), Expect = 5e-10
Identities = 49/147 (33%), Positives = 72/147 (48%), Gaps = 12/147 (8%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR----- 421
SDQ D++ + +VV NLYPF QT++KP VTVA+AVE IDIGG ++RA +
Sbjct: 83 SDQADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRATAKNFAHT 142
Query: 422 TTTGSPSSVTRPTTML*SKKSKRTNIIRRFGHKA----EISPEGVHSYFGL*PRHIGLLS 589
T +P+ L + + ++F +A + + +YF GL
Sbjct: 143 TVLTNPNQYEAYLQALQEQGEIPLALRQQFAGEAFALTNAYDQAIANYFS------GLSG 196
Query: 590 ASNTRXGXA---QLTLRYGMNPHQKXG 661
S + G + + LRYG NPHQ G
Sbjct: 197 DSANQFGLSGTLRQPLRYGENPHQSAG 223
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 95.1 bits (226), Expect = 2e-18
Identities = 42/73 (57%), Positives = 58/73 (79%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K ALLSVSDKTG++ A+ L G+++I++GGTA+ LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 204 VKTLHPAVHAGIL 242
VKTLHP +H G+L
Sbjct: 63 VKTLHPRIHGGLL 75
Score = 55.6 bits (128), Expect = 2e-06
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 11/141 (7%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTT 430
E+ ++ +I ++ NLYPF TVS+ +V + +A+ENIDIGG TLLR+ + T
Sbjct: 85 EEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRSAAKNYRSVTVL 144
Query: 431 GSPSSVTR-----PTTML*SKKSKRTNIIRRFGHKAEISPEGVHSYFGL*PRHIGLLSAS 595
PS R ++ + S K++ ++ F H A+ + +Y LL
Sbjct: 145 SDPSDYGRILKELRSSGIISDKTRAELAVKAFRHTADYD-AAIDTYLSR-----TLLGEE 198
Query: 596 NTRXGXAQ-LTLRYGMNPHQK 655
A + LRYG N HQK
Sbjct: 199 VLHLKFADGVKLRYGENWHQK 219
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 94.7 bits (225), Expect = 3e-18
Identities = 45/78 (57%), Positives = 61/78 (78%)
Frame = +3
Query: 18 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 197
N K AL+SVSDK GL+ AK+L + G+++I++GGTA+ L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 198 GRVKTLHPAVHAGILARL 251
GRVKTLHP + GILA L
Sbjct: 62 GRVKTLHPKIFGGILADL 79
Score = 42.3 bits (95), Expect = 0.015
Identities = 26/53 (49%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKP-DVTVADAVENIDIGGVTLLRA 412
S +D++ E I +VV NLYPF + K D V +ENIDIGGV LLRA
Sbjct: 83 SHVKDLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRA 133
Score = 39.9 bits (89), Expect = 0.080
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +1
Query: 418 KNHDRVTVVCDPADYDAVVKEI 483
KNH V VVCDPADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 94.7 bits (225), Expect = 3e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 210 TLHPAVHAGILAR 248
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 59.7 bits (138), Expect = 9e-08
Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
Frame = +2
Query: 296 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR---TTTGSPSSVTRP 457
I +VV NLYPF TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
Score = 33.5 bits (73), Expect = 7.0
Identities = 15/23 (65%), Positives = 19/23 (82%)
Frame = +3
Query: 516 TRQRLALKAFTHTSDYDLAISDY 584
TR LA+KAFTHT+ YD AIS++
Sbjct: 173 TRFALAVKAFTHTARYDSAISNH 195
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 93.5 bits (222), Expect = 6e-18
Identities = 45/74 (60%), Positives = 54/74 (72%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
L L SVSDKTGL A L G IASGGTA+ L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 207 KTLHPAVHAGILAR 248
KTLHP +H GILAR
Sbjct: 63 KTLHPMIHGGILAR 76
Score = 63.7 bits (148), Expect = 6e-09
Identities = 46/143 (32%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----T 424
D+ ++K + I +V+ NLYPF +T+S PD T +D +ENIDIGGV LLRA + T
Sbjct: 81 DRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRAAAKNYSRVT 140
Query: 425 TTGSPSSVTRPTTML*SKKSKRTNIIRRFGHKA-EISPE---GVHSYFGL*PRHIGLL-- 586
P+ ++ + ++ +R KA ++ + S+ R G +
Sbjct: 141 VICDPADYDEVSSEIEKTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSGLSRLSGGIEE 200
Query: 587 SASNTRXGXAQLTLRYGMNPHQK 655
S T LRYG NPHQK
Sbjct: 201 KTSLTLCAYPGQDLRYGENPHQK 223
Score = 40.7 bits (91), Expect = 0.046
Identities = 16/24 (66%), Positives = 20/24 (83%)
Frame = +1
Query: 418 KNHDRVTVVCDPADYDAVVKEIKE 489
KN+ RVTV+CDPADYD V EI++
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIEK 157
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 93.1 bits (221), Expect = 8e-18
Identities = 44/75 (58%), Positives = 56/75 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 204 VKTLHPAVHAGILAR 248
VKTLHPA+H GILAR
Sbjct: 63 VKTLHPAIHGGILAR 77
Score = 37.1 bits (82), Expect = 0.57
Identities = 20/41 (48%), Positives = 28/41 (68%), Gaps = 2/41 (4%)
Frame = +2
Query: 296 ISVVVCNLYPFVQTVSK--PDVTVADAVENIDIGGVTLLRA 412
I +V NLYPF +TV++ PD V +ENIDIGG ++R+
Sbjct: 94 IDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRS 131
Score = 33.9 bits (74), Expect = 5.3
Identities = 14/22 (63%), Positives = 18/22 (81%)
Frame = +3
Query: 519 RQRLALKAFTHTSDYDLAISDY 584
R+RLA KA+ HTS+YD AI+ Y
Sbjct: 161 RRRLAAKAYRHTSEYDAAITAY 182
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 92.3 bits (219), Expect = 1e-17
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
LALLSV DKTG+L LA++L + +++SGGTA+ LR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 207 KTLHPAVHAGILAR 248
KTLHP VH G+L R
Sbjct: 63 KTLHPKVHGGLLGR 76
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 91.9 bits (218), Expect = 2e-17
Identities = 42/72 (58%), Positives = 56/72 (77%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DKTGL LAK L E G++++++G TA+ + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 210 TLHPAVHAGILA 245
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 43.2 bits (97), Expect = 0.009
Identities = 22/54 (40%), Positives = 31/54 (57%)
Frame = +2
Query: 251 IHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+ + E + + E +VV NLYPFV+TV K D VE IDIGG ++R+
Sbjct: 89 VPAHMETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
Score = 38.3 bits (85), Expect = 0.25
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +3
Query: 507 DLGTRQRLALKAFTHTSDYDLAISDY 584
DL TRQRLA KAF HT+ YD A++ +
Sbjct: 171 DLKTRQRLAAKAFAHTASYDTAVATW 196
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 91.1 bits (216), Expect = 3e-17
Identities = 39/71 (54%), Positives = 55/71 (77%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDKTG++ A L ++++++GGTA+ LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 210 TLHPAVHAGIL 242
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/52 (40%), Positives = 34/52 (65%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
S + M+ E I +VV +LYPF +T+ V++A+A+E IDIGG ++R+
Sbjct: 92 SHESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 91.1 bits (216), Expect = 3e-17
Identities = 43/82 (52%), Positives = 57/82 (69%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
++ S K AL+S+SDKT L L L E G ++++GGT+ L AG++V V ++TR
Sbjct: 82 KSSTSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRF 141
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
PEML GRVKTLHP+VH GILAR
Sbjct: 142 PEMLDGRVKTLHPSVHGGILAR 163
Score = 43.6 bits (98), Expect = 0.007
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNLYPFVQTVSKPD-VTVADAVENIDIGGVTLLRA 412
E +++ + VVV NLYPF VS ++ D +ENIDIGG ++RA
Sbjct: 171 EALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
Score = 34.3 bits (75), Expect = 4.0
Identities = 21/64 (32%), Positives = 34/64 (53%)
Frame = +3
Query: 501 SDDLGTRQRLALKAFTHTSDYDLAISDYFPQAILARGXPN*P*DTV*THIRSXAQVFHDQ 680
+DD R++LA KAF H + YD A+S++ + + P P TV H++S + +
Sbjct: 248 NDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFP--PGLTVPLHLKSLLRYGENP 305
Query: 681 RQFA 692
Q A
Sbjct: 306 HQKA 309
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 90.2 bits (214), Expect = 6e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSV +K+G++ +K LS G LI++GGTA+ L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 64.5 bits (150), Expect = 3e-09
Identities = 29/50 (58%), Positives = 38/50 (76%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
Q D+ + + IS+VV NLYPFV+TVSK T+ +A+ENIDIGG TL+RA
Sbjct: 82 QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
Score = 34.3 bits (75), Expect = 4.0
Identities = 17/35 (48%), Positives = 21/35 (60%)
Frame = +3
Query: 498 SSDDLGTRQRLALKAFTHTSDYDLAISDYFPQAIL 602
SS L R++LALKAF H YD A+S Y + L
Sbjct: 166 SSITLEERKKLALKAFQHGCSYDAAVSQYLSKVEL 200
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 88.6 bits (210), Expect = 2e-16
Identities = 42/73 (57%), Positives = 55/73 (75%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DKTG+L LAK L G ++++SGGT L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 88.6 bits (210), Expect = 2e-16
Identities = 39/77 (50%), Positives = 54/77 (70%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKT ++ AK L E G +++++GGT R + AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 204 VKTLHPAVHAGILARLS 254
VKTLHP +H G+L + S
Sbjct: 63 VKTLHPMIHGGLLGKRS 79
Score = 56.0 bits (129), Expect = 1e-06
Identities = 25/53 (47%), Positives = 33/53 (62%)
Frame = +2
Query: 254 HSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
H M+ I +V NLYPF +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 81 HEHLSQMEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
Score = 33.9 bits (74), Expect = 5.3
Identities = 14/31 (45%), Positives = 20/31 (64%)
Frame = +3
Query: 495 TSSDDLGTRQRLALKAFTHTSDYDLAISDYF 587
+ +D RQ+LA K F HT+ YD I++YF
Sbjct: 159 SETDTYEFRQQLAAKVFRHTASYDAMIANYF 189
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 88.2 bits (209), Expect = 2e-16
Identities = 41/74 (55%), Positives = 56/74 (75%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K A+LSVS+KTG++ AK+L++ +L ++GGT R L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 204 VKTLHPAVHAGILA 245
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 65.3 bits (152), Expect = 2e-09
Identities = 40/105 (38%), Positives = 61/105 (58%), Gaps = 9/105 (8%)
Frame = +2
Query: 269 DMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTG 433
++ Q ++I +VV NLYPF QTV+ PDVT+ +A+ENIDIGG T+LRA + TT
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIV 144
Query: 434 SPSSVTRPTTML*S----KKSKRTNIIRRFGHKAEISPEGVHSYF 556
P+ T L + + +++ +I+ F H AE E + +F
Sbjct: 145 HPADYHEVLTRLRNDSLDESYRQSLMIKVFEHTAEYD-EAIVRFF 188
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 87.8 bits (208), Expect = 3e-16
Identities = 41/72 (56%), Positives = 55/72 (76%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSV+DK+GL+ A L++ G++L+++GGT R L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 210 TLHPAVHAGILA 245
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 87.8 bits (208), Expect = 3e-16
Identities = 43/76 (56%), Positives = 55/76 (72%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTG++ A+ L + G++L+++GGTA+ L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 210 TLHPAVHAGILARLST 257
TLHP VH GIL R T
Sbjct: 69 TLHPKVHGGILGRRGT 84
Score = 64.5 bits (150), Expect = 3e-09
Identities = 30/52 (57%), Positives = 39/52 (75%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+D M++ E I +VV NLYPF TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 84 TDDAIMQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
Score = 35.1 bits (77), Expect = 2.3
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +3
Query: 516 TRQRLALKAFTHTSDYDLAISDYFPQAI 599
TR LA+KAF HT+ YD I++YF Q +
Sbjct: 170 TRFDLAIKAFEHTAQYDSMIANYFGQLV 197
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 86.6 bits (205), Expect = 7e-16
Identities = 42/74 (56%), Positives = 56/74 (75%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV DK G+L LAK L + +++I+SGGT + L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 204 VKTLHPAVHAGILA 245
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 42.7 bits (96), Expect = 0.011
Identities = 25/57 (43%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Frame = +2
Query: 251 IHSDQEDMK---RQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
I ++E MK ++ I VV NLYPF + V + D++ + VE IDIGG T+LRA
Sbjct: 77 IRDNKEHMKTLEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 86.6 bits (205), Expect = 7e-16
Identities = 40/73 (54%), Positives = 56/73 (76%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
A++SV K G+ LAK+L E G +++++GGTA+ LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 47.6 bits (108), Expect = 4e-04
Identities = 24/54 (44%), Positives = 36/54 (66%)
Frame = +2
Query: 251 IHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+ D+E++++ + I VVV NLYPF + + K +T D +E IDIGG TL+RA
Sbjct: 78 VEKDKEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRA 130
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 86.2 bits (204), Expect = 9e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +H+GILA
Sbjct: 77 VKTLHPFIHSGILA 90
Score = 44.4 bits (100), Expect = 0.004
Identities = 29/82 (35%), Positives = 42/82 (51%)
Frame = +2
Query: 212 FTSSGTCWDLSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIG 391
F SG D H +Q + + + +VVCNLYPF TV+ + + VE IDIG
Sbjct: 83 FIHSGILADQRKAAHREQ--IAQLGIQAFDLVVCNLYPFQDTVAS-GASFDECVEQIDIG 139
Query: 392 GVTLLRAXPRTTTGSPSSVTRP 457
G +++RA + S + VT P
Sbjct: 140 GPSMVRAAAKNHP-SVAVVTSP 160
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 84.2 bits (199), Expect = 4e-15
Identities = 38/75 (50%), Positives = 54/75 (72%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK G++ A+ L++ G ++I++GGT L AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +H G+LAR
Sbjct: 63 VKTLHPKIHGGLLAR 77
Score = 53.6 bits (123), Expect = 6e-06
Identities = 24/40 (60%), Positives = 32/40 (80%)
Frame = +2
Query: 293 MISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+I +VV NLYPF +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
Score = 38.7 bits (86), Expect = 0.19
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +3
Query: 516 TRQRLALKAFTHTSDYDLAISDYFPQAI 599
TRQRLA K F HT+ YD I+DYF + +
Sbjct: 167 TRQRLAAKVFRHTAAYDALIADYFTKQV 194
Score = 35.1 bits (77), Expect = 2.3
Identities = 16/24 (66%), Positives = 17/24 (70%)
Frame = +1
Query: 418 KNHDRVTVVCDPADYDAVVKEIKE 489
KNH VTVV DPADY V+ EI E
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAE 159
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 84.2 bits (199), Expect = 4e-15
Identities = 37/75 (49%), Positives = 53/75 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDK G++ K L G +++++GGT + L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 210 TLHPAVHAGILARLS 254
TLHP +H GIL + S
Sbjct: 63 TLHPKIHGGILHKRS 77
Score = 40.7 bits (91), Expect = 0.046
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 14/150 (9%)
Frame = +2
Query: 248 IIH--SDQEDMKRQKY-EMISV-VVC-NLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
I+H SD+ +K+ K E++ + +VC NLYPF +T D + +ENIDIGG ++R+
Sbjct: 72 ILHKRSDENHIKQAKENEILGIDLVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
Query: 413 XPRT-----TTGSPSSVTRPTTML---*SKKSKRTNI-IRRFGHKAEISPEGVHSYFGL* 565
+ P + L + ++ R N+ I+ + H A + +Y
Sbjct: 131 AAKNYKDVMVLCDPLDYEKVIETLKKGQNDENFRLNLMIKAYEHTANYDAY-IANYMN-- 187
Query: 566 PRHIGLLSASNTRXGXAQLTLRYGMNPHQK 655
R G AS G +YG NPHQK
Sbjct: 188 ERFNGGFGASKFIVGQKVFDTKYGENPHQK 217
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 83.8 bits (198), Expect = 5e-15
Identities = 39/82 (47%), Positives = 57/82 (69%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK+GL+ AK L++ G+++I++GGT + L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 204 VKTLHPAVHAGILARLSTLTRK 269
VKTLHP VH G+L +S K
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHK 86
Score = 59.3 bits (137), Expect = 1e-07
Identities = 25/50 (50%), Positives = 39/50 (78%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
++ M+ K I +VV NLYPF++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 86 KQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 82.6 bits (195), Expect = 1e-14
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +HAG+LAR
Sbjct: 72 VKTLHPKIHAGLLAR 86
Score = 52.8 bits (121), Expect = 1e-05
Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 9/140 (6%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----T 424
D++ + + + I ++V NLYPFVQTVS + ++ AVE IDIGG ++LRA + T
Sbjct: 90 DEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRAAAKNFAAVT 149
Query: 425 TTGSPSSVTRPTTML*SKKSKRT-NIIRRFGHKA--EISPEGVHSYFGL*PRH-IGLLSA 592
P +R + + T + +R K +S H L + L A
Sbjct: 150 VVVDPEDYSRILEEIKTHHGSTTLSTRKRLAQKTFEHLSYYDAHIATYLAEKEGATTLPA 209
Query: 593 SNTRXGXAQLTLRYGMNPHQ 652
++ LRYG NPHQ
Sbjct: 210 RLPSIFKKKIDLRYGENPHQ 229
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.2 bits (194), Expect = 2e-14
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 210 TLHPAVHAGILAR 248
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
Score = 35.1 bits (77), Expect = 2.3
Identities = 20/46 (43%), Positives = 24/46 (52%)
Frame = +3
Query: 501 SDDLGTRQRLALKAFTHTSDYDLAISDYFPQAILARGXPN*P*DTV 638
S L TR LA KAF + YD ISDYF + + PN P T+
Sbjct: 166 SISLNTRLNLAAKAFKYIKQYDTMISDYFQHQLKLQ--PNKPHHTI 209
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 82.2 bits (194), Expect = 2e-14
Identities = 36/74 (48%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKT L+ K L+E G+++I++GGT + L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 204 VKTLHPAVHAGILA 245
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
Score = 55.6 bits (128), Expect = 2e-06
Identities = 25/39 (64%), Positives = 31/39 (79%)
Frame = +2
Query: 296 ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
I +VV NLYPF +T+SK DVT +A+ENIDIGG +LRA
Sbjct: 96 IDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 37.1 bits (82), Expect = 0.57
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +1
Query: 418 KNHDRVTVVCDPADYDAVVKEIKE 489
KNH VTV+ DPADY V+ +IKE
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE 160
Score = 34.3 bits (75), Expect = 4.0
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +3
Query: 480 NQREQTSSDDLGTRQRLALKAFTHTSDYDLAISDYFPQAI 599
NQ ++ S L ++ LA K F HT+ YD I+DY +
Sbjct: 156 NQIKEEGSVSLQKKRELAAKVFRHTAAYDALIADYLTNVV 195
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 81.8 bits (193), Expect = 2e-14
Identities = 39/75 (52%), Positives = 56/75 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK L SL + L++ ++LI+SGGT + ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +HAGIL++
Sbjct: 72 VKTLHPKIHAGILSK 86
Score = 46.8 bits (106), Expect = 7e-04
Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 8/141 (5%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGS 436
S +++K +Y+ I +V+ N YPF +T+ + + +ENID+GG T++RA +
Sbjct: 91 SHTKELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRAAAKNYNDV 149
Query: 437 P--SSVTRPTTML*SKKSKRTNIIRRFGHKAEISPEGVHSYF-GL*PRHIGLLSASN--- 598
+S + T++ ++ + + F K + +Y+ + + + +N
Sbjct: 150 TVITSSDQYETLINELENNKGSTSIEFREKMSLEAFSETAYYDAVISNYFNKIKKNNFPK 209
Query: 599 --TRXGXAQLTLRYGMNPHQK 655
G LRYG NPHQ+
Sbjct: 210 KKIIYGNLIEKLRYGENPHQE 230
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 81.0 bits (191), Expect = 4e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
Score = 43.2 bits (97), Expect = 0.009
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +2
Query: 236 DLSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAX 415
D +S +H Q +++ + +VV NLYPF + + +D +E IDIGG L+RA
Sbjct: 82 DTTSQMHRAQ--LQQLGVDAFDLVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAA 139
Query: 416 PRTTT 430
+ T
Sbjct: 140 AKNHT 144
Score = 33.1 bits (72), Expect = 9.2
Identities = 13/25 (52%), Positives = 20/25 (80%)
Frame = +3
Query: 519 RQRLALKAFTHTSDYDLAISDYFPQ 593
R +LA+KA++HTS+YDL IS + +
Sbjct: 171 RHQLAIKAYSHTSEYDLHISRWLSE 195
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 80.2 bits (189), Expect = 6e-14
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K ALLSV DKTG++ LA++L + +++SGGT L AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP VH G+L R
Sbjct: 92 VKTLHPKVHGGLLGR 106
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 76.6 bits (180), Expect = 8e-13
Identities = 36/75 (48%), Positives = 53/75 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV K G+ LA++ + G +++++G TA+ L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 210 TLHPAVHAGILARLS 254
TLHP +HAGILA ++
Sbjct: 71 TLHPYIHAGILADMT 85
Score = 39.5 bits (88), Expect = 0.11
Identities = 22/66 (33%), Positives = 37/66 (56%)
Frame = +2
Query: 212 FTSSGTCWDLSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIG 391
+ +G D+++ H+ Q ++ + +VV NLYPF TV + AD +E IDIG
Sbjct: 75 YIHAGILADMTNPEHAKQ--LEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIEKIDIG 131
Query: 392 GVTLLR 409
G +++R
Sbjct: 132 GPSMVR 137
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 75.8 bits (178), Expect = 1e-12
Identities = 36/74 (48%), Positives = 51/74 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
+ AL+SVSDKTG+ SLAK+L + ++LI + GT + L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +H GIL+
Sbjct: 69 VKTLHPKIHGGILS 82
Score = 44.4 bits (100), Expect = 0.004
Identities = 18/46 (39%), Positives = 29/46 (63%)
Frame = +2
Query: 275 KRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
K + I +V+ N YPF + V K ++ + + ++NIDIGGV L R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 74.1 bits (174), Expect = 4e-12
Identities = 38/72 (52%), Positives = 51/72 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDK+ L LA+ L ++++++GGT R L G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 210 TLHPAVHAGILA 245
TLHP +H GILA
Sbjct: 77 TLHPKIHGGILA 88
Score = 57.2 bits (132), Expect = 5e-07
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 19/150 (12%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TT 427
Q +++ I +V+ NLYPF +T++KP + ADA+ENIDIGG T++RA +
Sbjct: 95 QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRAAAKNWNRVAV 154
Query: 428 TGSPSSVTRPTTML*S-----KKSKRTNIIRR-FGHKAEISPEGVHSYFGL*PRH----- 574
P + + +L +S R N+ R+ F H A + SY RH
Sbjct: 155 IVDPEDYSSLSEVLGETEGTLPESFRRNMARKAFAHTAAYD-AAIASYLA---RHDDAGE 210
Query: 575 ---IGLLSASNTRXGXAQLTLRYGMNPHQK 655
G + G + LRYG NPHQ+
Sbjct: 211 ALDAGTIPEGLFVSGESVAELRYGENPHQQ 240
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 73.3 bits (172), Expect = 7e-12
Identities = 34/73 (46%), Positives = 47/73 (64%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 210 TLHPAVHAGILAR 248
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 39.9 bits (89), Expect = 0.080
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 409
SD ++ +I +V+ +LYPF TV+ + D +E IDIGG++L+R
Sbjct: 88 SDVREVGEYGLPLIDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIR 137
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 69.3 bits (162), Expect = 1e-10
Identities = 37/74 (50%), Positives = 49/74 (66%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
LA+L+VSDK + LA L G ++A+ GT R LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 207 KTLHPAVHAGILAR 248
KTL ++ GILAR
Sbjct: 62 KTLTVSLMGGILAR 75
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 69.3 bits (162), Expect = 1e-10
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
P++L G VKTLHP + GIL R
Sbjct: 75 PKILDGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 69.3 bits (162), Expect = 1e-10
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
P++L G VKTLHP + GIL R
Sbjct: 75 PKILDGHVKTLHPNIQGGILPR 96
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 68.9 bits (161), Expect = 2e-10
Identities = 37/73 (50%), Positives = 49/73 (67%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGLL LAK+L+ ++LIASGGTA+ L AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 210 TLHPAVHAGILAR 248
T+ + + +L R
Sbjct: 67 TISFEIASSLLFR 79
Score = 44.8 bits (101), Expect = 0.003
Identities = 42/127 (33%), Positives = 58/127 (45%), Gaps = 5/127 (3%)
Frame = +2
Query: 290 EMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTR 454
E I +VV NLYPF T+ K + +ENIDIGG TLLRA + T PS +
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRAGAKNFHSVTVLCDPSQYSE 153
Query: 455 PTTML*SKKSKRTNIIRRFGHKAEISPEGVHSYFGL*PRHIGLLSASNTRXGXAQLTLRY 634
L + F K + + +++ + G L+ ++ G A LRY
Sbjct: 154 ---FLKEFNGNNGSTTWEFRQKCAAAVYTMTAFYDM--AIAGFLTQNS---GAA---LRY 202
Query: 635 GMNPHQK 655
G NPHQK
Sbjct: 203 GENPHQK 209
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 68.5 bits (160), Expect = 2e-10
Identities = 33/75 (44%), Positives = 47/75 (62%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV K GL + L E G++ +++GGT + + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP + GIL R
Sbjct: 68 VKTLHPKIFGGILCR 82
Score = 46.0 bits (104), Expect = 0.001
Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Frame = +2
Query: 260 DQEDMKRQKYEM--ISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTG 433
+Q+ + +KYE+ I +V+ +LYPF TV+ + AD +E IDIGG++L+RA +
Sbjct: 86 EQDIQQIEKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRAAAKNYND 144
Query: 434 ----SPSSVTRPTTML*SKKSKRTNIIRRFGHKAEISPEGVHSYFGL*PRHIGLLSASNT 601
+ + +P + + +++ R E H Y + S
Sbjct: 145 VIIVASQAQYKPLLDMLMEHGATSSLEERRWMAKEAFAVSSH-YDSAIFNYFDAGEGSAF 203
Query: 602 RXG-XAQLTLRYGMNPHQK 655
R Q LRYG NPHQK
Sbjct: 204 RCSVNNQKQLRYGENPHQK 222
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/73 (45%), Positives = 46/73 (63%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K L+S+ +K L + + L E G ++ AS GTA+ L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 204 VKTLHPAVHAGIL 242
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 64.1 bits (149), Expect = 4e-09
Identities = 29/75 (38%), Positives = 48/75 (64%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 204 VKTLHPAVHAGILAR 248
+KTLH ++A ILA+
Sbjct: 68 IKTLHHKIYASILAQ 82
Score = 42.7 bits (96), Expect = 0.011
Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 3/60 (5%)
Frame = +2
Query: 242 SSIIHSDQEDMKR-QKYEMI--SVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+SI+ + D K +KY +I +VV N YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 77 ASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +3
Query: 18 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 197
N K A++SV DKT L LA L G+++I + GT + L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 198 GRVKTLHPAVHAGILAR 248
GRVK++ P + GILA+
Sbjct: 62 GRVKSIDPKLAGGILAK 78
Score = 36.7 bits (81), Expect = 0.75
Identities = 20/50 (40%), Positives = 29/50 (58%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+EDM + I +VV N +P + ++K +ENIDIGG +LLRA
Sbjct: 85 EEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLLENIDIGGYSLLRA 133
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/72 (45%), Positives = 49/72 (68%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 212
L+SVSD +GL L + L+ + A+ GT + L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 213 LHPAVHAGILAR 248
LHPAV +GIL+R
Sbjct: 61 LHPAVFSGILSR 72
Score = 50.0 bits (114), Expect = 8e-05
Identities = 24/58 (41%), Positives = 35/58 (60%)
Frame = +2
Query: 239 LSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
LS + D+KR Y +V+CNLY F + K ++ D +ENIDIGG++L+RA
Sbjct: 70 LSRRDEQSEADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 56.8 bits (131), Expect = 7e-07
Identities = 29/52 (55%), Positives = 34/52 (65%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
S DMKR I +VV NLYPF QTV++PDVT A NIDIGG ++RA
Sbjct: 102 SHARDMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRA 153
Score = 40.3 bits (90), Expect = 0.061
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 7/77 (9%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTARXLRN-----AGLTVQDVSDITRAPEM 191
L+SVSDKTGL L + + ++GGT + + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 192 LGGRVKTLHPAVHAGIL 242
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
Score = 34.3 bits (75), Expect = 4.0
Identities = 16/25 (64%), Positives = 18/25 (72%)
Frame = +3
Query: 510 LGTRQRLALKAFTHTSDYDLAISDY 584
L TR LA KAF HT+ YD AI+DY
Sbjct: 186 LDTRFELAQKAFDHTAAYDRAIADY 210
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 212
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 213 LHPAVHAGILA 245
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.2 bits (97), Expect = 0.009
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -3
Query: 409 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTD 308
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 42.3 bits (95), Expect = 0.015
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
Frame = +2
Query: 80 PVGMWPAVDCQWRYRQXASE-----RRPHSSRC--VGHHESTGDARRSGEN-FTSSGTCW 235
P WP CQ ++R S R P + VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 236 DLSSIIHSDQEDMKRQKYEMISVVVCNLYPFVQTVSKPDV 355
D SS +H + + K+ E SV V N + VSKP +
Sbjct: 247 D-SSPLHREVQQRKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 39.9 bits (89), Expect = 0.080
Identities = 19/36 (52%), Positives = 23/36 (63%)
Frame = -3
Query: 409 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH 302
A+ G AAD+DVLD + HG V R ERV+V HH
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHH 447
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.1 bits (87), Expect = 0.14
Identities = 23/57 (40%), Positives = 30/57 (52%)
Frame = -2
Query: 203 PTSEHLRCSRDVRHILNCEAGVPKRPGGTATGNQLQATFRQALC*RE*TRLV*NAEK 33
P H R + DV H+L+ +A + R GG A G QL A RQ + T LV N E+
Sbjct: 490 PAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTGLVGNGEE 546
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 38.3 bits (85), Expect = 0.25
Identities = 16/43 (37%), Positives = 31/43 (72%)
Frame = +3
Query: 45 SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI 173
SDK ++ K+L++ G++L+A+ GTAR L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 37.9 bits (84), Expect = 0.32
Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 6 NMASNGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDV 164
NM +GK ALLS+ DK LL +AK L G + A+ GTA+ L+ AG+ Q V
Sbjct: 70 NMKKSGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 36.7 bits (81), Expect = 0.75
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +3
Query: 48 DKTGLLSLAKSLSECGLQLIASGGTARXLRN 140
DK GL+ +A+SL E G +L A+ GTAR LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 36.3 bits (80), Expect = 0.99
Identities = 22/36 (61%), Positives = 23/36 (63%)
Frame = -3
Query: 409 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTDHH 302
AQ G AADVDVLD V L +RL ERVQV HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 1.3
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +3
Query: 189 MLGGRVKTLHPAVHAGILAR 248
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.1 bits (77), Expect = 2.3
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGL 149
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.1 bits (77), Expect = 2.3
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +3
Query: 33 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI-TRAPEML 194
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene
pglZ; n=2; Streptomyces coelicolor|Rep: Bacteriophage
(PhiC31) resistance gene pglZ - Streptomyces coelicolor
Length = 974
Score = 33.1 bits (72), Expect = 9.2
Identities = 16/49 (32%), Positives = 23/49 (46%)
Frame = +2
Query: 65 LVSKEPVGMWPAVDCQWRYRQXASERRPHSSRCVGHHESTGDARRSGEN 211
L+ P G WPAV W RQ A +G +++ G RR G++
Sbjct: 151 LLDATPPGSWPAVPGGWLSRQYALTALAQRRLRLGRYDTEGGPRRPGDD 199
>UniRef50_A2R5D4 Cluster: Contig An15c0130, complete genome; n=8;
Trichocomaceae|Rep: Contig An15c0130, complete genome -
Aspergillus niger
Length = 599
Score = 33.1 bits (72), Expect = 9.2
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +1
Query: 436 TVVCDPADYDAVVKEIKENKHHQT-IWAQGRD*P*RRSLIL 555
TVV DPA + +K+IKE H +T W R P RR +L
Sbjct: 272 TVVLDPAQKQSFIKDIKEYLHPRTRRWYSNRGIPYRRGYLL 312
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 764,798,405
Number of Sequences: 1657284
Number of extensions: 14355093
Number of successful extensions: 40319
Number of sequences better than 10.0: 64
Number of HSP's better than 10.0 without gapping: 38603
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40288
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 75833093035
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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