Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0610
(632 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 115 8e-25
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 111 1e-23
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 99 4e-20
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 100 6e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 8e-20
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 1e-19
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 97 3e-19
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 97 3e-19
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 96 5e-19
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 95 9e-19
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 95 1e-18
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 95 2e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 2e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 93 5e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 9e-18
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 1e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 91 2e-17
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 2e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 90 4e-17
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 89 1e-16
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 89 1e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 88 1e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 88 2e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 88 2e-16
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 87 4e-16
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 87 4e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 86 6e-16
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 86 8e-16
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 84 2e-15
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 84 2e-15
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 84 3e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 7e-15
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 9e-15
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 82 1e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 2e-14
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 80 4e-14
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 77 3e-13
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 77 5e-13
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 76 6e-13
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 76 8e-13
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 4e-12
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 6e-12
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 69 7e-11
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 7e-11
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 69 7e-11
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 69 7e-11
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 69 1e-10
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 65 2e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 64 3e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 8e-09
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 56 5e-07
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 50 4e-05
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 48 1e-04
UniRef50_A4EC20 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_A3HKM0 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 43 0.007
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 39 0.087
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 38 0.15
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 38 0.20
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 37 0.46
UniRef50_A5P3U3 Cluster: Putative uncharacterized protein; n=1; ... 36 0.81
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 0.81
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 35 1.4
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 35 1.4
UniRef50_A2R5D4 Cluster: Contig An15c0130, complete genome; n=8;... 33 4.3
UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene ... 33 5.7
UniRef50_Q121P4 Cluster: Cation-transporting ATPase; n=6; Proteo... 33 7.5
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 33 7.5
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 32 10.0
UniRef50_A5KA45 Cluster: Putative uncharacterized protein; n=2; ... 32 10.0
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 115 bits (277), Expect = 8e-25
Identities = 55/76 (72%), Positives = 66/76 (86%)
Frame = +3
Query: 21 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 200
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA+ LR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 201 RVKTLHPAVHAGILAR 248
RVKTLHPAVHAGILAR
Sbjct: 64 RVKTLHPAVHAGILAR 79
Score = 103 bits (248), Expect = 3e-21
Identities = 55/113 (48%), Positives = 68/113 (60%)
Frame = +2
Query: 239 LSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXP 418
L+ I D DM R + +I VV CN YPFV+TV+ P VTV +AVE IDIGGVTLLRA
Sbjct: 77 LARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAA 136
Query: 419 KNHDRVTVVCDPADYDAVVKEIKENKHHQTLWAQGRD*P*RRSLILSDYDFAI 577
KNH RVTVVC+P DY V E++ ++ T R + + YD AI
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAI 189
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/53 (47%), Positives = 30/53 (56%)
Frame = +1
Query: 472 SQRNQREQTSSDALGTRQRLALKAFTHTFGL*LRHIRTYFRKQYSXGASPTDL 630
S Q ++ +L TR++LALKAFTHT I YFRKQYS G S L
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYD-EAISDYFRKQYSKGVSQMPL 206
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 111 bits (268), Expect = 1e-23
Identities = 53/84 (63%), Positives = 62/84 (73%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
+D DM++ Y +I VVVCN YPFV+TVS P VTV DAVE IDIGGVTLLRA KNH RV
Sbjct: 77 ADTADMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRAAAKNHARV 136
Query: 437 TVVCDPADYDAVVKEIKENKHHQT 508
TVVCDPADY V +E++ + T
Sbjct: 137 TVVCDPADYPRVAEEMEGSGSRDT 160
Score = 109 bits (263), Expect = 4e-23
Identities = 54/75 (72%), Positives = 62/75 (82%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ AK L + GL L+ASGGTA+ LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 210 TLHPAVHAGILARLS 254
TLHPAVH GILAR S
Sbjct: 61 TLHPAVHGGILARKS 75
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 99 bits (238), Expect = 4e-20
Identities = 51/76 (67%), Positives = 61/76 (80%), Gaps = 1/76 (1%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
LALLSVSDKTGL+ LA++L E G QL++SGGTA+ L AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 204 VKTLHPAVHAGILARL 251
VKTLHP +H GILARL
Sbjct: 69 VKTLHPRIHGGILARL 84
Score = 66.9 bits (156), Expect = 4e-10
Identities = 32/68 (47%), Positives = 44/68 (64%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D+ D++ I +VV N YPF QTV++ V++ +A E IDIGG TL RA KN+ VT
Sbjct: 89 DRADLEALGIPPIQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARAAAKNYPHVT 148
Query: 440 VVCDPADY 463
V+ DP+ Y
Sbjct: 149 VLTDPSQY 156
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 99.5 bits (237), Expect = 6e-20
Identities = 52/76 (68%), Positives = 60/76 (78%), Gaps = 1/76 (1%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
LALLSVSDKTGL+ LA+SL E G QL++SGGTA+ L AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 204 VKTLHPAVHAGILARL 251
VKTLHP +H GILARL
Sbjct: 77 VKTLHPRIHGGILARL 92
Score = 65.7 bits (153), Expect = 9e-10
Identities = 32/68 (47%), Positives = 44/68 (64%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D+ D++ I +VV N YPF QTV++ V++ +A E IDIGG TL RA KN+ VT
Sbjct: 97 DRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARAAAKNYPYVT 156
Query: 440 VVCDPADY 463
V+ DP+ Y
Sbjct: 157 VLTDPSQY 164
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 99.1 bits (236), Expect = 8e-20
Identities = 46/72 (63%), Positives = 60/72 (83%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ A+SL+ G++LI++GGTA+ + +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 210 TLHPAVHAGILA 245
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 69.7 bits (163), Expect = 5e-11
Identities = 36/87 (41%), Positives = 51/87 (58%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVV 445
E MK I ++V N YPF TV + +D +ENIDIGG ++RA KNH+ V VV
Sbjct: 91 EAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRAASKNHEDVAVV 149
Query: 446 CDPADYDAVVKEIKENKHHQTLWAQGR 526
D DYDAV++++ ++ TL + R
Sbjct: 150 VDVNDYDAVLEDLARHEGSTTLLLRRR 176
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 98.7 bits (235), Expect = 1e-19
Identities = 46/72 (63%), Positives = 59/72 (81%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL A +LS+ G++L+++GGT R L AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 210 TLHPAVHAGILA 245
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
Score = 62.9 bits (146), Expect = 6e-09
Identities = 32/77 (41%), Positives = 46/77 (59%)
Frame = +2
Query: 296 ISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDPADYDAVV 475
I ++V N YPF +T+ K D VENID+GG ++RA KNH V VV D +DY A++
Sbjct: 150 IDLLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRAAAKNHADVAVVVDVSDYGAIL 208
Query: 476 KEIKENKHHQTLWAQGR 526
E+ E+ + T + R
Sbjct: 209 AELAEHDGNLTATTRRR 225
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 97.1 bits (231), Expect = 3e-19
Identities = 42/77 (54%), Positives = 56/77 (72%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D+ ++K + I +V+ N YPF +T+S PD T +D +ENIDIGGV LLRA KN+ RVT
Sbjct: 81 DRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRAAAKNYSRVT 140
Query: 440 VVCDPADYDAVVKEIKE 490
V+CDPADYD V EI++
Sbjct: 141 VICDPADYDEVSSEIEK 157
Score = 93.5 bits (222), Expect = 4e-18
Identities = 45/74 (60%), Positives = 54/74 (72%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
L L SVSDKTGL A L G IASGGTA+ L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 207 KTLHPAVHAGILAR 248
KTLHP +H GILAR
Sbjct: 63 KTLHPMIHGGILAR 76
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 97.1 bits (231), Expect = 3e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGL+ LA++L ++L+++GGTA +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 210 TLHPAVHAGILAR 248
TLHP VH G+L R
Sbjct: 71 TLHPMVHGGLLGR 83
Score = 66.1 bits (154), Expect = 7e-10
Identities = 35/89 (39%), Positives = 49/89 (55%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D M + I +++ N YPF Q +K D T+ADAV+ IDIGG +LR+ KN RV
Sbjct: 87 DDAVMAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRSAAKNFARVA 146
Query: 440 VVCDPADYDAVVKEIKENKHHQTLWAQGR 526
V P Y ++ E++ HH L A+ R
Sbjct: 147 VATSPDQYPDLLAELQ--AHHGQLSAEKR 173
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 96.3 bits (229), Expect = 5e-19
Identities = 45/73 (61%), Positives = 58/73 (79%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDK G++ A++LS+ G++L+++GGTAR L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 210 TLHPAVHAGILAR 248
TLHP VH GIL R
Sbjct: 70 TLHPKVHGGILGR 82
Score = 81.0 bits (191), Expect = 2e-14
Identities = 36/78 (46%), Positives = 51/78 (65%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D M + + I +VV N YPF QTV++PD ++ DAVENIDIGG T++R+ KNH V
Sbjct: 86 DDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVA 145
Query: 440 VVCDPADYDAVVKEIKEN 493
+V +DY A++ E+ N
Sbjct: 146 IVVKSSDYPAIITELDNN 163
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 95.5 bits (227), Expect = 9e-19
Identities = 48/76 (63%), Positives = 60/76 (78%), Gaps = 1/76 (1%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGG 200
+LALLSVSDK+G++ LA+ L +E LI+SGGTA+ L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 201 RVKTLHPAVHAGILAR 248
RVKTLHP +H GILAR
Sbjct: 63 RVKTLHPRIHGGILAR 78
Score = 79.4 bits (187), Expect = 7e-14
Identities = 36/78 (46%), Positives = 52/78 (66%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
SDQ D++ + +VV N YPF QT++KP VTVA+AVE IDIGG ++RA KN
Sbjct: 83 SDQADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRATAKNFAHT 142
Query: 437 TVVCDPADYDAVVKEIKE 490
TV+ +P Y+A ++ ++E
Sbjct: 143 TVLTNPNQYEAYLQALQE 160
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 95.1 bits (226), Expect = 1e-18
Identities = 42/73 (57%), Positives = 58/73 (79%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K ALLSVSDKTG++ A+ L G+++I++GGTA+ LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 204 VKTLHPAVHAGIL 242
VKTLHP +H G+L
Sbjct: 63 VKTLHPRIHGGLL 75
Score = 77.4 bits (182), Expect = 3e-13
Identities = 33/76 (43%), Positives = 53/76 (69%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVV 445
E+ ++ +I ++ N YPF TVS+ +V + +A+ENIDIGG TLLR+ KN+ VTV+
Sbjct: 85 EEAAKEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRSAAKNYRSVTVL 144
Query: 446 CDPADYDAVVKEIKEN 493
DP+DY ++KE++ +
Sbjct: 145 SDPSDYGRILKELRSS 160
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 94.7 bits (225), Expect = 2e-18
Identities = 45/78 (57%), Positives = 61/78 (78%)
Frame = +3
Query: 18 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 197
N K AL+SVSDK GL+ AK+L + G+++I++GGTA+ L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 198 GRVKTLHPAVHAGILARL 251
GRVKTLHP + GILA L
Sbjct: 62 GRVKTLHPKIFGGILADL 79
Score = 75.4 bits (177), Expect = 1e-12
Identities = 41/77 (53%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKP-DVTVADAVENIDIGGVTLLRAXPKNHDR 433
S +D++ E I +VV N YPF + K D V +ENIDIGGV LLRA KNH
Sbjct: 83 SHVKDLRDNFIEPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRAAAKNHRN 140
Query: 434 VTVVCDPADYDAVVKEI 484
V VVCDPADYD V+K I
Sbjct: 141 VVVVCDPADYDKVIKSI 157
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 94.7 bits (225), Expect = 2e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 210 TLHPAVHAGILAR 248
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 76.6 bits (180), Expect = 5e-13
Identities = 37/70 (52%), Positives = 47/70 (67%), Gaps = 4/70 (5%)
Frame = +2
Query: 296 ISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDR----VTVVCDPADY 463
I +VV N YPF TV++PD T+ DA+ENIDIGG T++RA KNH V +V DP DY
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDPEDY 155
Query: 464 DAVVKEIKEN 493
+V E+K N
Sbjct: 156 AGIVAELKAN 165
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 93.1 bits (221), Expect = 5e-18
Identities = 44/75 (58%), Positives = 56/75 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 204 VKTLHPAVHAGILAR 248
VKTLHPA+H GILAR
Sbjct: 63 VKTLHPAIHGGILAR 77
Score = 59.3 bits (137), Expect = 8e-08
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 296 ISVVVCNXYPFVQTVSK--PDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDPADYDA 469
I +V N YPF +TV++ PD V +ENIDIGG ++R+ KNHD V V+ DPADY
Sbjct: 94 IDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRSAAKNHDAVLVLVDPADYAL 150
Query: 470 VVKE 481
+++
Sbjct: 151 ALQD 154
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 92.3 bits (219), Expect = 9e-18
Identities = 43/74 (58%), Positives = 57/74 (77%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
LALLSV DKTG+L LA++L + +++SGGTA+ LR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 207 KTLHPAVHAGILAR 248
KTLHP VH G+L R
Sbjct: 63 KTLHPKVHGGLLGR 76
Score = 60.5 bits (140), Expect = 3e-08
Identities = 29/76 (38%), Positives = 46/76 (60%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D + MK E I ++ N YPF + +SK ++ + + +E IDIGG ++RA KN+ V
Sbjct: 80 DDDVMKAHFIEPIDILCVNLYPF-EEMSKKNLPLEELIEFIDIGGPAMIRAASKNYKDVA 138
Query: 440 VVCDPADYDAVVKEIK 487
V+ DP+DY ++ IK
Sbjct: 139 VLTDPSDYPMAIEAIK 154
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 91.9 bits (218), Expect = 1e-17
Identities = 42/72 (58%), Positives = 56/72 (77%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DKTGL LAK L E G++++++G TA+ + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 210 TLHPAVHAGILA 245
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 60.5 bits (140), Expect = 3e-08
Identities = 32/80 (40%), Positives = 43/80 (53%)
Frame = +2
Query: 251 IHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHD 430
+ + E + + E +VV N YPFV+TV K D VE IDIGG ++R+ KNH
Sbjct: 89 VPAHMETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRSAAKNHA 147
Query: 431 RVTVVCDPADYDAVVKEIKE 490
V +V DP Y VV+ E
Sbjct: 148 AVAIVTDPNFYGDVVRAAAE 167
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 91.1 bits (216), Expect = 2e-17
Identities = 39/71 (54%), Positives = 55/71 (77%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDKTG++ A L ++++++GGTA+ LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 210 TLHPAVHAGIL 242
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 60.9 bits (141), Expect = 2e-08
Identities = 26/77 (33%), Positives = 47/77 (61%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
S + M+ E I +VV + YPF +T+ V++A+A+E IDIGG ++R+ KN V
Sbjct: 92 SHESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRSAAKNFHSV 151
Query: 437 TVVCDPADYDAVVKEIK 487
V+ + ++Y + +E++
Sbjct: 152 AVITNTSEYGPIAEELR 168
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 91.1 bits (216), Expect = 2e-17
Identities = 43/82 (52%), Positives = 57/82 (69%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
++ S K AL+S+SDKT L L L E G ++++GGT+ L AG++V V ++TR
Sbjct: 82 KSSTSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRF 141
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
PEML GRVKTLHP+VH GILAR
Sbjct: 142 PEMLDGRVKTLHPSVHGGILAR 163
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Frame = +2
Query: 266 EDMKRQKYEMISVVVCNXYPFVQTVSKPD-VTVADAVENIDIGGVTLLRAXPKNHDRVTV 442
E +++ + VVV N YPF VS ++ D +ENIDIGG ++RA KNH V V
Sbjct: 171 EALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRAAAKNHRDVLV 230
Query: 443 VCDPADYDAVVKEIKENKHHQ 505
V D DY A+++ ++ + Q
Sbjct: 231 VVDSEDYPALLEFLRGDNDDQ 251
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 90.2 bits (214), Expect = 4e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSV +K+G++ +K LS G LI++GGTA+ L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 81.0 bits (191), Expect = 2e-14
Identities = 36/77 (46%), Positives = 52/77 (67%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTV 442
Q D+ + + IS+VV N YPFV+TVSK T+ +A+ENIDIGG TL+RA KN V +
Sbjct: 82 QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRASSKNFQNVLI 141
Query: 443 VCDPADYDAVVKEIKEN 493
+ DP+DY + + I+ +
Sbjct: 142 IVDPSDYKWIGERIQSS 158
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 88.6 bits (210), Expect = 1e-16
Identities = 42/73 (57%), Positives = 55/73 (75%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DKTG+L LAK L G ++++SGGT L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Frame = +2
Query: 251 IHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADA-VENIDIGGVTLLRAXPKNH 427
+ D E++K E I +VV N YPF + + ++ DA VE IDIGG TL+RA KNH
Sbjct: 78 VEKDLEEIKENSIEPIDIVVVNLYPFEKKMK--ELKDIDALVEFIDIGGPTLVRAAAKNH 135
Query: 428 DRVTVVCDPADYDAVVKEIKEN 493
RV+V+ D DY ++++K N
Sbjct: 136 KRVSVLTDIEDYGWFIEKLKMN 157
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 88.6 bits (210), Expect = 1e-16
Identities = 39/77 (50%), Positives = 54/77 (70%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKT ++ AK L E G +++++GGT R + AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 204 VKTLHPAVHAGILARLS 254
VKTLHP +H G+L + S
Sbjct: 63 VKTLHPMIHGGLLGKRS 79
Score = 71.7 bits (168), Expect = 1e-11
Identities = 34/77 (44%), Positives = 45/77 (58%)
Frame = +2
Query: 254 HSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDR 433
H M+ I +V N YPF +TV KPDV+ D +ENIDIGG ++LR+ KN +
Sbjct: 81 HEHLSQMEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRSAAKNFED 140
Query: 434 VTVVCDPADYDAVVKEI 484
V VV P DY+ V+ I
Sbjct: 141 VLVVTGPTDYNRVLAAI 157
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 88.2 bits (209), Expect = 1e-16
Identities = 41/74 (55%), Positives = 56/74 (75%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K A+LSVS+KTG++ AK+L++ +L ++GGT R L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 204 VKTLHPAVHAGILA 245
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 83.4 bits (197), Expect = 4e-15
Identities = 36/75 (48%), Positives = 52/75 (69%)
Frame = +2
Query: 269 DMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVC 448
++ Q ++I +VV N YPF QTV+ PDVT+ +A+ENIDIGG T+LRA KN+ VT +
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIV 144
Query: 449 DPADYDAVVKEIKEN 493
PADY V+ ++ +
Sbjct: 145 HPADYHEVLTRLRND 159
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 87.8 bits (208), Expect = 2e-16
Identities = 41/72 (56%), Positives = 55/72 (76%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSV+DK+GL+ A L++ G++L+++GGT R L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 210 TLHPAVHAGILA 245
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/74 (33%), Positives = 41/74 (55%)
Frame = +2
Query: 272 MKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCD 451
+K ++ N Y F ++ + + AVE +DIGG +LRA KN + V+ D
Sbjct: 144 LKELGIRTFDLICVNLYNFADAAAR-GLDLRGAVEEVDIGGPCMLRATAKNFHSMLVLPD 202
Query: 452 PADYDAVVKEIKEN 493
PADY A ++E+++N
Sbjct: 203 PADYQAAMQEMRDN 216
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 87.8 bits (208), Expect = 2e-16
Identities = 43/76 (56%), Positives = 55/76 (72%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTG++ A+ L + G++L+++GGTA+ L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 210 TLHPAVHAGILARLST 257
TLHP VH GIL R T
Sbjct: 69 TLHPKVHGGILGRRGT 84
Score = 82.6 bits (195), Expect = 7e-15
Identities = 38/84 (45%), Positives = 58/84 (69%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
+D M++ E I +VV N YPF TV+KPD T+ADAVENIDIGG T++R+ KNH V
Sbjct: 84 TDDAIMQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRSAAKNHKDV 143
Query: 437 TVVCDPADYDAVVKEIKENKHHQT 508
+V + D++A++ E+ ++++ T
Sbjct: 144 AIVVNNHDFNAILAEMDQHQNSLT 167
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 86.6 bits (205), Expect = 4e-16
Identities = 42/74 (56%), Positives = 56/74 (75%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV DK G+L LAK L + +++I+SGGT + L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 204 VKTLHPAVHAGILA 245
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/84 (44%), Positives = 50/84 (59%), Gaps = 3/84 (3%)
Frame = +2
Query: 251 IHSDQEDMK---RQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPK 421
I ++E MK ++ I VV N YPF + V + D++ + VE IDIGG T+LRA K
Sbjct: 77 IRDNKEHMKTLEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRAAAK 135
Query: 422 NHDRVTVVCDPADYDAVVKEIKEN 493
N V V+ D DY+ V+ EIKEN
Sbjct: 136 NFKDVVVLSDKKDYEKVMNEIKEN 159
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 86.6 bits (205), Expect = 4e-16
Identities = 40/73 (54%), Positives = 56/73 (76%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
A++SV K G+ LAK+L E G +++++GGTA+ LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 210 TLHPAVHAGILAR 248
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 70.5 bits (165), Expect = 3e-11
Identities = 34/80 (42%), Positives = 53/80 (66%)
Frame = +2
Query: 251 IHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHD 430
+ D+E++++ + I VVV N YPF + + K +T D +E IDIGG TL+RA KN
Sbjct: 78 VEKDKEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRAAAKNFF 136
Query: 431 RVTVVCDPADYDAVVKEIKE 490
RV ++ DP DYD V++++K+
Sbjct: 137 RVVILVDPEDYDWVIEKLKK 156
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 86.2 bits (204), Expect = 6e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +H+GILA
Sbjct: 77 VKTLHPFIHSGILA 90
Score = 57.6 bits (133), Expect = 2e-07
Identities = 33/91 (36%), Positives = 46/91 (50%)
Frame = +2
Query: 212 FTSSGTCWDLSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIG 391
F SG D H +Q + + + +VVCN YPF TV+ + + VE IDIG
Sbjct: 83 FIHSGILADQRKAAHREQ--IAQLGIQAFDLVVCNLYPFQDTVAS-GASFDECVEQIDIG 139
Query: 392 GVTLLRAXPKNHDRVTVVCDPADYDAVVKEI 484
G +++RA KNH V VV P Y V + +
Sbjct: 140 GPSMVRAAAKNHPSVAVVTSPERYADVAEAV 170
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 85.8 bits (203), Expect = 8e-16
Identities = 39/65 (60%), Positives = 48/65 (73%)
Frame = +2
Query: 296 ISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDPADYDAVV 475
I +VV N YPF +T+SK DVT +A+ENIDIGG +LRA KNH VTV+ DPADY V+
Sbjct: 96 IDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRAASKNHQDVTVIVDPADYSPVL 155
Query: 476 KEIKE 490
+IKE
Sbjct: 156 NQIKE 160
Score = 82.2 bits (194), Expect = 9e-15
Identities = 36/74 (48%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDKT L+ K L+E G+++I++GGT + L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 204 VKTLHPAVHAGILA 245
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 84.2 bits (199), Expect = 2e-15
Identities = 38/75 (50%), Positives = 54/75 (72%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK G++ A+ L++ G ++I++GGT L AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +H G+LAR
Sbjct: 63 VKTLHPKIHGGLLAR 77
Score = 81.8 bits (193), Expect = 1e-14
Identities = 39/66 (59%), Positives = 48/66 (72%)
Frame = +2
Query: 293 MISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDPADYDAV 472
+I +VV N YPF +T+ +PDVT AVENIDIGG ++LR+ KNH VTVV DPADY V
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTV 153
Query: 473 VKEIKE 490
+ EI E
Sbjct: 154 LGEIAE 159
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 84.2 bits (199), Expect = 2e-15
Identities = 37/75 (49%), Positives = 53/75 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDK G++ K L G +++++GGT + L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 210 TLHPAVHAGILARLS 254
TLHP +H GIL + S
Sbjct: 63 TLHPKIHGGILHKRS 77
Score = 63.3 bits (147), Expect = 5e-09
Identities = 34/91 (37%), Positives = 58/91 (63%), Gaps = 5/91 (5%)
Frame = +2
Query: 248 IIH--SDQEDMKRQKY-EMISV-VVC-NXYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
I+H SD+ +K+ K E++ + +VC N YPF +T D + +ENIDIGG ++R+
Sbjct: 72 ILHKRSDENHIKQAKENEILGIDLVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
Query: 413 XPKNHDRVTVVCDPADYDAVVKEIKENKHHQ 505
KN+ V V+CDP DY+ V++ +K+ ++ +
Sbjct: 131 AAKNYKDVMVLCDPLDYEKVIETLKKGQNDE 161
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 83.8 bits (198), Expect = 3e-15
Identities = 39/82 (47%), Positives = 57/82 (69%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK+GL+ AK L++ G+++I++GGT + L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 204 VKTLHPAVHAGILARLSTLTRK 269
VKTLHP VH G+L +S K
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHK 86
Score = 72.5 bits (170), Expect = 8e-12
Identities = 31/70 (44%), Positives = 48/70 (68%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTV 442
++ M+ K I +VV N YPF++TVSKP+V + +A+ENIDIGG +++R+ KN+ V
Sbjct: 86 KQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLV 145
Query: 443 VCDPADYDAV 472
+ DP DY +
Sbjct: 146 LTDPNDYKKI 155
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 82.6 bits (195), Expect = 7e-15
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +HAG+LAR
Sbjct: 72 VKTLHPKIHAGLLAR 86
Score = 77.8 bits (183), Expect = 2e-13
Identities = 39/89 (43%), Positives = 56/89 (62%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D++ + + + I ++V N YPFVQTVS + ++ AVE IDIGG ++LRA KN VT
Sbjct: 90 DEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRAAAKNFAAVT 149
Query: 440 VVCDPADYDAVVKEIKENKHHQTLWAQGR 526
VV DP DY +++EIK + TL + R
Sbjct: 150 VVVDPEDYSRILEEIKTHHGSTTLSTRKR 178
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.2 bits (194), Expect = 9e-15
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 210 TLHPAVHAGILAR 248
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
Score = 49.6 bits (113), Expect = 6e-05
Identities = 25/85 (29%), Positives = 42/85 (49%)
Frame = +2
Query: 230 CWDLSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLR 409
C + S + D+ + + + I +V+ N YPF + +E IDIGG ++R
Sbjct: 76 CAGILSRKNLDESIIHKYGIQPIDMVIVNFYPFHLILQNKQHDSEKILEYIDIGGPNMVR 135
Query: 410 AXPKNHDRVTVVCDPADYDAVVKEI 484
A KN+ ++ D DYD ++ EI
Sbjct: 136 AAAKNYKNTVIIVDNNDYDNILNEI 160
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 81.8 bits (193), Expect = 1e-14
Identities = 39/75 (52%), Positives = 56/75 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK L SL + L++ ++LI+SGGT + ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP +HAGIL++
Sbjct: 72 VKTLHPKIHAGILSK 86
Score = 65.7 bits (153), Expect = 9e-10
Identities = 28/80 (35%), Positives = 51/80 (63%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
S +++K +Y+ I +V+ N YPF +T+ + + +ENID+GG T++RA KN++ V
Sbjct: 91 SHTKELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRAAAKNYNDV 149
Query: 437 TVVCDPADYDAVVKEIKENK 496
TV+ Y+ ++ E++ NK
Sbjct: 150 TVITSSDQYETLINELENNK 169
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 81.0 bits (191), Expect = 2e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/84 (36%), Positives = 48/84 (57%)
Frame = +2
Query: 236 DLSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAX 415
D +S +H Q +++ + +VV N YPF + + +D +E IDIGG L+RA
Sbjct: 82 DTTSQMHRAQ--LQQLGVDAFDLVVVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAA 139
Query: 416 PKNHDRVTVVCDPADYDAVVKEIK 487
KNH RV V+ DP+DY V+ ++
Sbjct: 140 AKNHTRVVVIVDPSDYIHVINSLE 163
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 80.2 bits (189), Expect = 4e-14
Identities = 39/75 (52%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K ALLSV DKTG++ LA++L + +++SGGT L AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP VH G+L R
Sbjct: 92 VKTLHPKVHGGLLGR 106
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Frame = +2
Query: 260 DQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVT 439
D M + I ++V N YPF + +S+ + + +E ID+GG ++RA KN V
Sbjct: 110 DDAIMAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLIEYIDVGGPAMIRAAAKNFKDVA 168
Query: 440 VVCDPADYDAVVKEIKEN---KHHQTL 511
VV DP+DY VVK + N H Q L
Sbjct: 169 VVVDPSDYPEVVKTLSSNVGFSHEQRL 195
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 77.4 bits (182), Expect = 3e-13
Identities = 40/80 (50%), Positives = 49/80 (61%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
S DMKR I +VV N YPF QTV++PDVT A NIDIGG ++RA KN RV
Sbjct: 102 SHARDMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRASAKNFLRV 161
Query: 437 TVVCDPADYDAVVKEIKENK 496
V DPADY+ V E++ +
Sbjct: 162 ASVVDPADYNTVADEMEHRQ 181
Score = 40.3 bits (90), Expect = 0.038
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 7/77 (9%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTARXLRN-----AGLTVQDVSDITRAPEM 191
L+SVSDKTGL L + + ++GGT + + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 192 LGGRVKTLHPAVHAGIL 242
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/75 (48%), Positives = 53/75 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV K G+ LA++ + G +++++G TA+ L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 210 TLHPAVHAGILARLS 254
TLHP +HAGILA ++
Sbjct: 71 TLHPYIHAGILADMT 85
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/93 (34%), Positives = 50/93 (53%)
Frame = +2
Query: 212 FTSSGTCWDLSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIG 391
+ +G D+++ H+ Q ++ + +VV N YPF TV + AD +E IDIG
Sbjct: 75 YIHAGILADMTNPEHAKQ--LEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIEKIDIG 131
Query: 392 GVTLLRAXPKNHDRVTVVCDPADYDAVVKEIKE 490
G +++R KNH V +V DPADY V + +
Sbjct: 132 GPSMVRGAAKNHATVAIVTDPADYALVASRVAD 164
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 76.2 bits (179), Expect = 6e-13
Identities = 33/78 (42%), Positives = 52/78 (66%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTV 442
Q +++ I +V+ N YPF +T++KP + ADA+ENIDIGG T++RA KN +RV V
Sbjct: 95 QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRAAAKNWNRVAV 154
Query: 443 VCDPADYDAVVKEIKENK 496
+ DP DY ++ + + E +
Sbjct: 155 IVDPEDYSSLSEVLGETE 172
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/72 (52%), Positives = 51/72 (70%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SVSDK+ L LA+ L ++++++GGT R L G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 210 TLHPAVHAGILA 245
TLHP +H GILA
Sbjct: 77 TLHPKIHGGILA 88
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 75.8 bits (178), Expect = 8e-13
Identities = 36/74 (48%), Positives = 51/74 (68%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
+ AL+SVSDKTG+ SLAK+L + ++LI + GT + L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 204 VKTLHPAVHAGILA 245
VKTLHP +H GIL+
Sbjct: 69 VKTLHPKIHGGILS 82
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/73 (36%), Positives = 43/73 (58%)
Frame = +2
Query: 275 KRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDP 454
K + I +V+ N YPF + V K ++ + + ++NIDIGGV L R+ KN+ VTVV +
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARSAAKNYKYVTVVVNI 150
Query: 455 ADYDAVVKEIKEN 493
Y + E+ +N
Sbjct: 151 NQYSKLSSEMDKN 163
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 73.3 bits (172), Expect = 4e-12
Identities = 34/73 (46%), Positives = 47/73 (64%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 210 TLHPAVHAGILAR 248
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/108 (31%), Positives = 53/108 (49%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
SD ++ +I +V+ + YPF TV+ + D +E IDIGG++L+R KN + V
Sbjct: 88 SDVREVGEYGLPLIDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIRGAAKNFEDV 146
Query: 437 TVVCDPADYDAVVKEIKENKHHQTLWAQGRD*P*RRSLILSDYDFAIF 580
++ A Y +KE +L A+ R + S YD AIF
Sbjct: 147 VIISSRAQYAGFYSLLKEQGARTSL-AERRHYAREAFAVSSAYDSAIF 193
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 72.9 bits (171), Expect = 6e-12
Identities = 32/86 (37%), Positives = 52/86 (60%)
Frame = +2
Query: 239 LSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXP 418
LS + D+KR Y +V+CN Y F + K ++ D +ENIDIGG++L+RA
Sbjct: 70 LSRRDEQSEADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRAAA 126
Query: 419 KNHDRVTVVCDPADYDAVVKEIKENK 496
KN+ VTV P DY+ ++K++++ +
Sbjct: 127 KNYQHVTVASSPEDYNIIIKDLRDGE 152
Score = 62.5 bits (145), Expect = 8e-09
Identities = 33/72 (45%), Positives = 49/72 (68%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 212
L+SVSD +GL L + L+ + A+ GT + L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 213 LHPAVHAGILAR 248
LHPAV +GIL+R
Sbjct: 61 LHPAVFSGILSR 72
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 69.3 bits (162), Expect = 7e-11
Identities = 41/104 (39%), Positives = 55/104 (52%)
Frame = +2
Query: 290 EMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTVVCDPADYDA 469
E I +VV N YPF T+ K + +ENIDIGG TLLRA KN VTV+CDP+ Y
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRAGAKNFHSVTVLCDPSQYSE 153
Query: 470 VVKEIKENKHHQTLWAQGRD*P*RRSLILSDYDFAIFGLTSASN 601
+KE N + T W + + + YD AI G + ++
Sbjct: 154 FLKEFNGN-NGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQNS 196
Score = 68.9 bits (161), Expect = 9e-11
Identities = 37/73 (50%), Positives = 49/73 (67%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
ALLSVSDKTGLL LAK+L+ ++LIASGGTA+ L AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 210 TLHPAVHAGILAR 248
T+ + + +L R
Sbjct: 67 TISFEIASSLLFR 79
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 69.3 bits (162), Expect = 7e-11
Identities = 37/74 (50%), Positives = 49/74 (66%)
Frame = +3
Query: 27 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRV 206
LA+L+VSDK + LA L G ++A+ GT R LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 207 KTLHPAVHAGILAR 248
KTL ++ GILAR
Sbjct: 62 KTLTVSLMGGILAR 75
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/78 (30%), Positives = 38/78 (48%)
Frame = +2
Query: 257 SDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRV 436
+D+ +++R + +V CN Y +P E ID+GG +LRA KN V
Sbjct: 79 ADRAEVERHGLTRVHLVCCNYYRLPDP--QPAQPFERFRELIDVGGPAMLRAAAKNCAHV 136
Query: 437 TVVCDPADYDAVVKEIKE 490
+ DP DY V+K + +
Sbjct: 137 VPLSDPDDYAGVLKALAD 154
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 69.3 bits (162), Expect = 7e-11
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
P++L G VKTLHP + GIL R
Sbjct: 75 PKILDGHVKTLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 69.3 bits (162), Expect = 7e-11
Identities = 35/82 (42%), Positives = 49/82 (59%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 183 PEMLGGRVKTLHPAVHAGILAR 248
P++L G VKTLHP + GIL R
Sbjct: 75 PKILDGHVKTLHPNIQGGILPR 96
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 68.5 bits (160), Expect = 1e-10
Identities = 33/75 (44%), Positives = 47/75 (62%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K AL+SV K GL + L E G++ +++GGT + + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 204 VKTLHPAVHAGILAR 248
VKTLHP + GIL R
Sbjct: 68 VKTLHPKIFGGILCR 82
Score = 59.3 bits (137), Expect = 8e-08
Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 2/114 (1%)
Frame = +2
Query: 260 DQEDMKRQKYEM--ISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDR 433
+Q+ + +KYE+ I +V+ + YPF TV+ + AD +E IDIGG++L+RA KN++
Sbjct: 86 EQDIQQIEKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRAAAKNYND 144
Query: 434 VTVVCDPADYDAVVKEIKENKHHQTLWAQGRD*P*RRSLILSDYDFAIFGLTSA 595
V +V A Y ++ + E+ +L + R + S YD AIF A
Sbjct: 145 VIIVASQAQYKPLLDMLMEHGATSSL-EERRWMAKEAFAVSSHYDSAIFNYFDA 197
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/73 (45%), Positives = 46/73 (63%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K L+S+ +K L + + L E G ++ AS GTA+ L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 204 VKTLHPAVHAGIL 242
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 64.1 bits (149), Expect = 3e-09
Identities = 29/75 (38%), Positives = 48/75 (64%)
Frame = +3
Query: 24 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGR 203
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 204 VKTLHPAVHAGILAR 248
+KTLH ++A ILA+
Sbjct: 68 IKTLHHKIYASILAQ 82
Score = 60.9 bits (141), Expect = 2e-08
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Frame = +2
Query: 242 SSIIHSDQEDMKR-QKYEMI--SVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 412
+SI+ + D K +KY +I +VV N YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 77 ASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
Query: 413 XPKNHDRVTVVCDPADYDAVVKEIKENKH 499
KN+ V VV P Y ++V E+ N +
Sbjct: 137 AAKNYKNVLVVTQPNLYQSIVNEMNLNNN 165
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 62.5 bits (145), Expect = 8e-09
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +3
Query: 18 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLG 197
N K A++SV DKT L LA L G+++I + GT + L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 198 GRVKTLHPAVHAGILAR 248
GRVK++ P + GILA+
Sbjct: 62 GRVKSIDPKLAGGILAK 78
Score = 56.4 bits (130), Expect = 5e-07
Identities = 28/76 (36%), Positives = 43/76 (56%)
Frame = +2
Query: 263 QEDMKRQKYEMISVVVCNXYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPKNHDRVTV 442
+EDM + I +VV N +P + ++K +ENIDIGG +LLRA KN+ V
Sbjct: 85 EEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLLENIDIGGYSLLRAAAKNYKDVVA 143
Query: 443 VCDPADYDAVVKEIKE 490
+ DP DY V+ +++
Sbjct: 144 LADPKDYQTVIDNLED 159
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/62 (53%), Positives = 37/62 (59%)
Frame = -2
Query: 493 VLFDFFDYSIVVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXV 314
V F ++ V+GRV DD VVL AQ AADVDVLDRV V LR RLDER+ V
Sbjct: 695 VRFHLVEHDRVIGRVDDDRHVAVVLRRRAQHRRAADVDVLDRVGERAVVLRNRLDERIQV 754
Query: 313 TD 308
D
Sbjct: 755 HD 756
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 55.2 bits (127), Expect = 1e-06
Identities = 29/54 (53%), Positives = 33/54 (61%)
Frame = -2
Query: 463 VVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXVTDHH 302
V+G V DDGD VVLG A+ G AAD+DVLD + G V R ERV V HH
Sbjct: 394 VIGVVNDDGDVAVVLGCGAEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHH 447
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 50.4 bits (115), Expect = 4e-05
Identities = 33/60 (55%), Positives = 35/60 (58%)
Frame = -2
Query: 481 FFDYSIVVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXVTDHH 302
F + VVGRV DD VVLG AQ G AADVDVLD V L +RL ERV V HH
Sbjct: 410 FGQHGGVVGRVNDDCHIAVVLGRRAQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +3
Query: 33 LLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVKT 212
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 213 LHPAVHAGILA 245
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_A4EC20 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 666
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/53 (50%), Positives = 31/53 (58%)
Frame = -2
Query: 466 IVVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXVTD 308
I+VGRV DDG+ VL AQ G A DVDVLD VR G + + E V V D
Sbjct: 496 IIVGRVGDDGNARGVLSGGAQHGGATDVDVLDGVREGDLGVGDGFLELVQVDD 548
>UniRef50_A3HKM0 Cluster: Putative uncharacterized protein; n=2;
Pseudomonas putida|Rep: Putative uncharacterized protein
- Pseudomonas putida (strain GB-1)
Length = 602
Score = 43.6 bits (98), Expect = 0.004
Identities = 29/55 (52%), Positives = 30/55 (54%)
Frame = -2
Query: 478 FDYSIVVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXV 314
FD + VV V DGD VVLG A G AADVDVLD R RL ERV V
Sbjct: 438 FDDAGVVAGVDHDGDVFVVLGCRADHGRAADVDVLDGGRQVTARLGNGGFERVQV 492
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 42.7 bits (96), Expect = 0.007
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
Frame = +2
Query: 80 PVGMWPAVDCQWRYRQXASE-----RRPHSSRC--VGHHESTGDARRSGEN-FTSSGTCW 235
P WP CQ ++R S R P + VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 236 DLSSIIHSDQEDMKRQKYEMISVVVCNXYPFVQTVSKPDV 355
D SS +H + + K+ E SV V N + VSKP +
Sbjct: 247 D-SSPLHREVQQRKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.1 bits (87), Expect = 0.087
Identities = 23/57 (40%), Positives = 30/57 (52%)
Frame = -1
Query: 203 PTSEHLRCSRDVRHILNCEAGVPKRPGGTATGNQLQATFRQALC*RE*TRLV*NAEK 33
P H R + DV H+L+ +A + R GG A G QL A RQ + T LV N E+
Sbjct: 490 PAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTGLVGNGEE 546
Score = 33.1 bits (72), Expect = 5.7
Identities = 21/37 (56%), Positives = 21/37 (56%)
Frame = -2
Query: 424 VLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXV 314
VLG Q G AADVDVLDRV V L ERV V
Sbjct: 417 VLGRRTQHGRAADVDVLDRVGQAAVGLGGDRLERVQV 453
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 38.3 bits (85), Expect = 0.15
Identities = 16/43 (37%), Positives = 31/43 (72%)
Frame = +3
Query: 45 SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI 173
SDK ++ K+L++ G++L+A+ GTAR L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Frame = +3
Query: 6 NMASNGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDV 164
NM +GK ALLS+ DK LL +AK L G + A+ GTA+ L+ AG+ Q V
Sbjct: 70 NMKKSGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 36.7 bits (81), Expect = 0.46
Identities = 17/31 (54%), Positives = 23/31 (74%)
Frame = +3
Query: 48 DKTGLLSLAKSLSECGLQLIASGGTARXLRN 140
DK GL+ +A+SL E G +L A+ GTAR LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_A5P3U3 Cluster: Putative uncharacterized protein; n=1;
Methylobacterium sp. 4-46|Rep: Putative uncharacterized
protein - Methylobacterium sp. 4-46
Length = 659
Score = 35.9 bits (79), Expect = 0.81
Identities = 25/52 (48%), Positives = 27/52 (51%)
Frame = -2
Query: 463 VVGRVTDDGDPVVVLGLCAQEGHAADVDVLDRVRXGHVRLRYRLDERVXVTD 308
V+G V D VVVLG AADVDVLD + G RL ERV V D
Sbjct: 500 VIGDVDHHRDVVVVLGRRPDHRRAADVDVLDALGRGAPGRERRL-ERVEVDD 550
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 0.81
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +3
Query: 189 MLGGRVKTLHPAVHAGILAR 248
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +3
Query: 30 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGL 149
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +3
Query: 33 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI-TRAPEML 194
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_A2R5D4 Cluster: Contig An15c0130, complete genome; n=8;
Trichocomaceae|Rep: Contig An15c0130, complete genome -
Aspergillus niger
Length = 599
Score = 33.5 bits (73), Expect = 4.3
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +2
Query: 437 TVVCDPADYDAVVKEIKENKHHQT-LWAQGRD*P*RRSLIL 556
TVV DPA + +K+IKE H +T W R P RR +L
Sbjct: 272 TVVLDPAQKQSFIKDIKEYLHPRTRRWYSNRGIPYRRGYLL 312
>UniRef50_O86683 Cluster: Bacteriophage (PhiC31) resistance gene
pglZ; n=2; Streptomyces coelicolor|Rep: Bacteriophage
(PhiC31) resistance gene pglZ - Streptomyces coelicolor
Length = 974
Score = 33.1 bits (72), Expect = 5.7
Identities = 16/49 (32%), Positives = 23/49 (46%)
Frame = +2
Query: 65 LVSKEPVGMWPAVDCQWRYRQXASERRPHSSRCVGHHESTGDARRSGEN 211
L+ P G WPAV W RQ A +G +++ G RR G++
Sbjct: 151 LLDATPPGSWPAVPGGWLSRQYALTALAQRRLRLGRYDTEGGPRRPGDD 199
>UniRef50_Q121P4 Cluster: Cation-transporting ATPase; n=6;
Proteobacteria|Rep: Cation-transporting ATPase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 816
Score = 32.7 bits (71), Expect = 7.5
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Frame = +3
Query: 3 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRA 182
Q +A G A+ V + L + + E G+ L A A+ L + G TV ++D+T
Sbjct: 565 QAVAGRGMSAV--VEGRALRLGSPRFMQELGVDLGACAARAQALEDEGRTVSWLADVTVQ 622
Query: 183 PEMLGGRV--KTLHPAVHAGILARLSTLTRKT 272
P++LG +L PA I ARL L +T
Sbjct: 623 PQLLGLMAFGDSLKPAAGPAI-ARLHALGIQT 653
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 32.7 bits (71), Expect = 7.5
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +3
Query: 6 NMASNGKLAL-LSVSDKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDI 173
++ S+G + L + DK ++LAK G QL+A+ GTA L GL V V I
Sbjct: 931 HVPSHGNVLLTVRDEDKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 32.3 bits (70), Expect = 10.0
Identities = 16/54 (29%), Positives = 26/54 (48%)
Frame = +3
Query: 48 DKTGLLSLAKSLSECGLQLIASGGTARXLRNAGLTVQDVSDITRAPEMLGGRVK 209
DK + LA+ G +L+A+ GTA AG+T V + P L +++
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIR 1002
>UniRef50_A5KA45 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 4034
Score = 32.3 bits (70), Expect = 10.0
Identities = 13/22 (59%), Positives = 15/22 (68%)
Frame = +2
Query: 8 HGVKWKTSSSQRFRQDGSTLVS 73
HGV WK S SQR+ GST+ S
Sbjct: 3071 HGVMWKNSLSQRYHNSGSTMHS 3092
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 562,678,299
Number of Sequences: 1657284
Number of extensions: 10485639
Number of successful extensions: 32759
Number of sequences better than 10.0: 71
Number of HSP's better than 10.0 without gapping: 31769
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32738
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46881492319
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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