Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0494
(694 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine dehydro... 176 5e-44
U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine dehydro... 176 5e-44
BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
BT006740-1|AAP35386.1| 173|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
BC064027-1|AAH64027.1| 173|Homo sapiens DPYD protein protein. 176 5e-44
BC008379-1|AAH08379.1| 173|Homo sapiens DPYD protein protein. 176 5e-44
AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine dehyd... 176 5e-44
BC108742-1|AAI08743.1| 173|Homo sapiens DPYD protein protein. 173 5e-43
>U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.0 bits (124), Expect = 5e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>BT006740-1|AAP35386.1| 173|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 173
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVD 560
TEEG INIGGLQ FA +
Sbjct: 145 TEEGPINIGGLQQFATE 161
>BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>BC064027-1|AAH64027.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVD 560
TEEG INIGGLQ FA +
Sbjct: 145 TEEGPINIGGLQQFATE 161
>BC008379-1|AAH08379.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVD 560
TEEG INIGGLQ FA +
Sbjct: 145 TEEGPINIGGLQQFATE 161
>AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.0 bits (124), Expect = 5e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 176 bits (429), Expect = 5e-44
Identities = 77/92 (83%), Positives = 82/92 (89%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVCPTSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCPTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/37 (54%), Positives = 24/37 (64%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVDIFMKMGIPXTLDPNTKPATK 620
TEEG INIGGLQ FA ++F M IP +P+ P K
Sbjct: 145 TEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPEK 181
>BC108742-1|AAI08743.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 173 bits (421), Expect = 5e-43
Identities = 76/92 (82%), Positives = 81/92 (88%)
Frame = +1
Query: 244 EQEFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKXFITSIANXNYYGAAKA 423
E FDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+K FITSIAN NYYGAAK
Sbjct: 56 ENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKM 115
Query: 424 ILSDNPLGLTCGMVCPTSDLCVGGCNLHALKK 519
I SDNPLGLTCGMVC TSDLCVGGCNL+A ++
Sbjct: 116 IFSDNPLGLTCGMVCSTSDLCVGGCNLYATEE 147
Score = 54.8 bits (126), Expect = 3e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Frame = +2
Query: 89 LLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKQHWKRNADRKCTTCPTLNKN 253
+LSK+ DIE++L LNP + + L ++ K K+HWKRN D+ C C L N
Sbjct: 4 VLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENN 58
Score = 31.1 bits (67), Expect = 3.9
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = +3
Query: 510 TEEGAINIGGLQHFAVD 560
TEEG INIGGLQ FA +
Sbjct: 145 TEEGPINIGGLQQFATE 161
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,869,872
Number of Sequences: 237096
Number of extensions: 2202180
Number of successful extensions: 3811
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3687
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3811
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7951235188
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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