Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0438
(747 letters)
Database: spombe
5004 sequences; 2,362,478 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SPCC794.09c |ef1a-a||translation elongation factor EF-1 alpha Ef... 155 6e-39
SPAC23A1.10 |ef1a-b||translation elongation factor EF-1 alpha Ef... 155 8e-39
SPBC839.15c |ef1a-c||translation elongation factor EF-1 alpha Ef... 155 8e-39
SPCC584.04 |sup35|erf3|translation release factor eRF3 |Schizosa... 94 2e-20
SPBC25B2.01 ||SPBC2G5.08|elongation factor 1 alpha related prote... 87 3e-18
SPBC9B6.04c |tuf1||mitochondrial translation elongation factor E... 72 1e-13
SPCP31B10.07 |eft202||translation elongation factor 2 |Schizosac... 36 0.008
SPAC513.01c |eft201|eft2-1, etf2, SPAPYUK71.04c|translation elon... 36 0.008
SPBC17G9.09 |tif213||translation initiation factor eIF2 gamma su... 34 0.019
SPBC1306.01c ||SPBC409.22c|translation elongation factor G|Schiz... 34 0.025
SPBC660.10 |||translation elongation factor G|Schizosaccharomyce... 31 0.13
SPCC364.02c |bis1||stress response protein Bis1|Schizosaccharomy... 29 0.70
SPAC4D7.09 |tif223||translation initiation factor eIF2B|Schizosa... 27 2.8
SPAC56F8.03 |||translation initiation factor IF2 |Schizosaccharo... 27 3.8
SPBC1703.06 |pof10||F-box protein Pof10|Schizosaccharomyces pomb... 27 3.8
SPCC63.03 |||DNAJ domain protein, DNAJC11 family|Schizosaccharom... 27 3.8
SPBC215.13 |||sequence orphan|Schizosaccharomyces pombe|chr 2|||... 26 5.0
SPAC1B3.04c |||mitochondrial GTPase Guf1 |Schizosaccharomyces po... 26 5.0
SPCC70.08c |||methyltransferase |Schizosaccharomyces pombe|chr 3... 26 6.6
SPAC1687.08 |||sequence orphan|Schizosaccharomyces pombe|chr 1||... 26 6.6
SPBC146.14c |sec26|SPBC337.01c|coatomer beta subunit |Schizosacc... 25 8.7
SPAC8F11.09c |nnt1||nicotinamide N-methyltransferase Nnt1 |Schiz... 25 8.7
>SPCC794.09c |ef1a-a||translation elongation factor EF-1 alpha
Ef1a-a |Schizosaccharomyces pombe|chr 3|||Manual
Length = 460
Score = 155 bits (376), Expect = 6e-39
Identities = 72/83 (86%), Positives = 77/83 (92%)
Frame = +1
Query: 256 ALWKFETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTRE 435
ALWKFET KY VT+I APGHRDFIKNMITGTSQADCAVLI+ GTGEFEAGISK+GQTRE
Sbjct: 76 ALWKFETPKYNVTVIDAPGHRDFIKNMITGTSQADCAVLIIGGGTGEFEAGISKDGQTRE 135
Query: 436 HALLAFTLGVKQLIVGVNKMDST 504
HALLA+TLGVKQLIV VNKMD+T
Sbjct: 136 HALLAYTLGVKQLIVAVNKMDTT 158
Score = 151 bits (365), Expect = 1e-37
Identities = 69/75 (92%), Positives = 72/75 (96%)
Frame = +2
Query: 32 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL 211
MGKEK HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEA E+GKGSFKYAWVL
Sbjct: 1 MGKEKGHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEATELGKGSFKYAWVL 60
Query: 212 DKLKAERELGITIDM 256
DKLKAERE GITID+
Sbjct: 61 DKLKAERERGITIDI 75
>SPAC23A1.10 |ef1a-b||translation elongation factor EF-1 alpha
Ef1a-b |Schizosaccharomyces pombe|chr 1|||Manual
Length = 460
Score = 155 bits (375), Expect = 8e-39
Identities = 71/83 (85%), Positives = 77/83 (92%)
Frame = +1
Query: 256 ALWKFETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTRE 435
ALWKFET KY VT+I APGHRDFIKNMITGTSQADCA+LI+ GTGEFEAGISK+GQTRE
Sbjct: 76 ALWKFETPKYNVTVIDAPGHRDFIKNMITGTSQADCAILIIGGGTGEFEAGISKDGQTRE 135
Query: 436 HALLAFTLGVKQLIVGVNKMDST 504
HALLA+TLGVKQLIV VNKMD+T
Sbjct: 136 HALLAYTLGVKQLIVAVNKMDTT 158
Score = 151 bits (365), Expect = 1e-37
Identities = 69/75 (92%), Positives = 72/75 (96%)
Frame = +2
Query: 32 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL 211
MGKEK HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEA E+GKGSFKYAWVL
Sbjct: 1 MGKEKGHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEATELGKGSFKYAWVL 60
Query: 212 DKLKAERELGITIDM 256
DKLKAERE GITID+
Sbjct: 61 DKLKAERERGITIDI 75
>SPBC839.15c |ef1a-c||translation elongation factor EF-1 alpha
Ef1a-c |Schizosaccharomyces pombe|chr 2|||Manual
Length = 460
Score = 155 bits (375), Expect = 8e-39
Identities = 71/83 (85%), Positives = 77/83 (92%)
Frame = +1
Query: 256 ALWKFETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTRE 435
ALWKFET KY VT+I APGHRDFIKNMITGTSQADCA+LI+ GTGEFEAGISK+GQTRE
Sbjct: 76 ALWKFETPKYNVTVIDAPGHRDFIKNMITGTSQADCAILIIGGGTGEFEAGISKDGQTRE 135
Query: 436 HALLAFTLGVKQLIVGVNKMDST 504
HALLA+TLGVKQLIV VNKMD+T
Sbjct: 136 HALLAYTLGVKQLIVAVNKMDTT 158
Score = 151 bits (365), Expect = 1e-37
Identities = 69/75 (92%), Positives = 72/75 (96%)
Frame = +2
Query: 32 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL 211
MGKEK HIN+VVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEA E+GKGSFKYAWVL
Sbjct: 1 MGKEKGHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEATELGKGSFKYAWVL 60
Query: 212 DKLKAERELGITIDM 256
DKLKAERE GITID+
Sbjct: 61 DKLKAERERGITIDI 75
>SPCC584.04 |sup35|erf3|translation release factor eRF3
|Schizosaccharomyces pombe|chr 3|||Manual
Length = 662
Score = 93.9 bits (223), Expect = 2e-20
Identities = 41/77 (53%), Positives = 55/77 (71%)
Frame = +1
Query: 268 FETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALL 447
FET +++ APGH+ ++ NMI G SQAD VL+++A GEFEAG + GQTREHA+L
Sbjct: 311 FETEHRRFSLLDAPGHKGYVTNMINGASQADIGVLVISARRGEFEAGFERGGQTREHAVL 370
Query: 448 AFTLGVKQLIVGVNKMD 498
A T G+ L+V +NKMD
Sbjct: 371 ARTQGINHLVVVINKMD 387
Score = 85.4 bits (202), Expect = 8e-18
Identities = 37/71 (52%), Positives = 52/71 (73%)
Frame = +2
Query: 44 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLK 223
K H+NIV IGHVD+GKST G++++ G +DKRT+EK E+EA+E GK S+ +W LD
Sbjct: 236 KEHVNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAKEAGKESWYLSWALDSTS 295
Query: 224 AERELGITIDM 256
ERE G T+++
Sbjct: 296 EEREKGKTVEV 306
>SPBC25B2.01 ||SPBC2G5.08|elongation factor 1 alpha related
protein|Schizosaccharomyces pombe|chr 2|||Manual
Length = 592
Score = 87.0 bits (206), Expect = 3e-18
Identities = 41/77 (53%), Positives = 50/77 (64%)
Frame = +1
Query: 268 FETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALL 447
FE+ K I APGHRDFI MI G S AD AVL+V + FE G +NGQTREHA L
Sbjct: 250 FESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYL 309
Query: 448 AFTLGVKQLIVGVNKMD 498
LG+ +++V VNK+D
Sbjct: 310 LRALGISEIVVSVNKLD 326
Score = 81.4 bits (192), Expect = 1e-16
Identities = 35/73 (47%), Positives = 51/73 (69%)
Frame = +2
Query: 44 KTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLK 223
K +++VV GHVDSGKST G ++++ G I+ R+++K EA GKGSF YAW+LD +
Sbjct: 175 KPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTE 234
Query: 224 AERELGITIDMLS 262
ER G+T+D+ S
Sbjct: 235 EERARGVTMDVAS 247
>SPBC9B6.04c |tuf1||mitochondrial translation elongation factor
EF-Tu Tuf1 |Schizosaccharomyces pombe|chr 2|||Manual
Length = 439
Score = 71.7 bits (168), Expect = 1e-13
Identities = 35/81 (43%), Positives = 52/81 (64%)
Frame = +1
Query: 265 KFETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHAL 444
++ET+ + + PGH D+IKNMITG + D A+++V+A G+ QTREH L
Sbjct: 110 EYETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATDGQMP-------QTREHLL 162
Query: 445 LAFTLGVKQLIVGVNKMDSTE 507
LA +GVKQ++V +NK+D E
Sbjct: 163 LARQVGVKQIVVYINKVDMVE 183
Score = 37.1 bits (82), Expect = 0.003
Identities = 26/71 (36%), Positives = 35/71 (49%)
Frame = +2
Query: 38 KEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDK 217
++K H+NI IGHVD GK+T T I KC ++G+ SF +DK
Sbjct: 49 RKKPHVNIGTIGHVDHGKTTLTA-AITKC--------------LSDLGQASFMDYSQIDK 93
Query: 218 LKAERELGITI 250
E+ GITI
Sbjct: 94 APEEKARGITI 104
>SPCP31B10.07 |eft202||translation elongation factor 2
|Schizosaccharomyces pombe|chr 3|||Manual
Length = 842
Score = 35.5 bits (78), Expect = 0.008
Identities = 17/32 (53%), Positives = 19/32 (59%)
Frame = +2
Query: 32 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCG 127
MGK N+ VI HVD GKST T L+ K G
Sbjct: 13 MGKPSNVRNMSVIAHVDHGKSTLTDSLVQKAG 44
>SPAC513.01c |eft201|eft2-1, etf2, SPAPYUK71.04c|translation
elongation factor 2 |Schizosaccharomyces pombe|chr
1|||Manual
Length = 842
Score = 35.5 bits (78), Expect = 0.008
Identities = 17/32 (53%), Positives = 19/32 (59%)
Frame = +2
Query: 32 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCG 127
MGK N+ VI HVD GKST T L+ K G
Sbjct: 13 MGKPSNVRNMSVIAHVDHGKSTLTDSLVQKAG 44
>SPBC17G9.09 |tif213||translation initiation factor eIF2 gamma
subunit|Schizosaccharomyces pombe|chr 2|||Manual
Length = 446
Score = 34.3 bits (75), Expect = 0.019
Identities = 19/71 (26%), Positives = 33/71 (46%)
Frame = +1
Query: 286 YVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGV 465
+V+ + PGH + M+ G + D A+L++A QT EH + +
Sbjct: 109 HVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMQL 162
Query: 466 KQLIVGVNKMD 498
K +I+ NK+D
Sbjct: 163 KHIIILQNKVD 173
>SPBC1306.01c ||SPBC409.22c|translation elongation factor
G|Schizosaccharomyces pombe|chr 2|||Manual
Length = 770
Score = 33.9 bits (74), Expect = 0.025
Identities = 23/65 (35%), Positives = 34/65 (52%)
Frame = +2
Query: 56 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 235
NI + H+DSGK+T T ++Y G I K+ E+ +G +D ++ ERE
Sbjct: 61 NIGISAHIDSGKTTFTERVLYYTGRI---------KDIHEV-RGKDNVGAKMDFMELERE 110
Query: 236 LGITI 250
GITI
Sbjct: 111 KGITI 115
Score = 31.5 bits (68), Expect = 0.13
Identities = 20/57 (35%), Positives = 28/57 (49%)
Frame = +1
Query: 268 FETSKYYVTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREH 438
FE S Y + II PGH DF + D AVL++ A +G I+ + Q R +
Sbjct: 141 FEKS-YNINIIDTPGHIDFTIEVERALRVLDGAVLVLCAVSGVQSQTITVDRQMRRY 196
>SPBC660.10 |||translation elongation factor G|Schizosaccharomyces
pombe|chr 2|||Manual
Length = 813
Score = 31.5 bits (68), Expect = 0.13
Identities = 22/66 (33%), Positives = 33/66 (50%)
Frame = +2
Query: 56 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 235
N+ +I H+D+GK+T T ++Y G F + G V+D L AER+
Sbjct: 30 NVGIIAHIDAGKTTLTEKMLYYGG---------FTSHFGNVDTGD----TVMDYLPAERQ 76
Query: 236 LGITID 253
GITI+
Sbjct: 77 RGITIN 82
Score = 26.2 bits (55), Expect = 5.0
Identities = 22/70 (31%), Positives = 33/70 (47%)
Frame = +1
Query: 289 VTIIXAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVK 468
+ +I PGH DF + + D AV I+ + AG+ QT+ A G+
Sbjct: 95 INLIDTPGHADFTFEVERSVAVLDGAVAII-----DGSAGV--EAQTKVVWKQATKRGIP 147
Query: 469 QLIVGVNKMD 498
++I VNKMD
Sbjct: 148 KVIF-VNKMD 156
>SPCC364.02c |bis1||stress response protein Bis1|Schizosaccharomyces
pombe|chr 3|||Manual
Length = 384
Score = 29.1 bits (62), Expect = 0.70
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = -1
Query: 306 SXNDGNIVLASFELPESISIVIPSSRSAFSLSNTQAYLKDPLPISWASFSNFSMVRLSIP 127
S + + L S+ P S+S + + A ++YL+ PL S S S + +R SIP
Sbjct: 305 SVDSASTALNSYSTPNSVSRKLTNLTPAARRLVARSYLRSPLHGSSPSASRHTALRTSIP 364
>SPAC4D7.09 |tif223||translation initiation factor
eIF2B|Schizosaccharomyces pombe|chr 1|||Manual
Length = 468
Score = 27.1 bits (57), Expect = 2.8
Identities = 22/66 (33%), Positives = 30/66 (45%)
Frame = -1
Query: 372 EHSAISLRGSCDHVLDEISVSRSXNDGNIVLASFELPESISIVIPSSRSAFSLSNTQAYL 193
EH+A+ L S +L IS R N GNI L S + + S + L+ + A
Sbjct: 5 EHAALPLASS-PSILGPISGGR--NRGNIQLQSIPIEFQAVVFAGFGNSLYPLTGSDALP 61
Query: 192 KDPLPI 175
K LPI
Sbjct: 62 KALLPI 67
>SPAC56F8.03 |||translation initiation factor IF2
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 1079
Score = 26.6 bits (56), Expect = 3.8
Identities = 11/28 (39%), Positives = 15/28 (53%)
Frame = +1
Query: 295 IIXAPGHRDFIKNMITGTSQADCAVLIV 378
II PGH F GTS + A+L++
Sbjct: 553 IIDTPGHESFTNLRSRGTSLCNIAILVI 580
>SPBC1703.06 |pof10||F-box protein Pof10|Schizosaccharomyces
pombe|chr 2|||Manual
Length = 662
Score = 26.6 bits (56), Expect = 3.8
Identities = 19/61 (31%), Positives = 25/61 (40%)
Frame = -2
Query: 272 SNFQRAYRL*YXAHAQPLVCPIPKHI*RILYPFPGPPSRTSRWYVCQYHHICRSSDQWWW 93
SN +R R + V +PK I I++ F P S S C+Y S D W
Sbjct: 13 SNLRRMNRDHSSNNTNRTVLNLPKEILIIIFSFLDPRSLLSAQCTCKYWKKLLSDDLSWR 72
Query: 92 T 90
T
Sbjct: 73 T 73
>SPCC63.03 |||DNAJ domain protein, DNAJC11
family|Schizosaccharomyces pombe|chr 3|||Manual
Length = 642
Score = 26.6 bits (56), Expect = 3.8
Identities = 14/39 (35%), Positives = 22/39 (56%)
Frame = -1
Query: 258 SISIVIPSSRSAFSLSNTQAYLKDPLPISWASFSNFSMV 142
+IS+ +P+ FSL+ ++ K LPI W S + S V
Sbjct: 408 NISVGVPTGSITFSLNWSRLGQKISLPIMWCSVFDRSAV 446
>SPBC215.13 |||sequence orphan|Schizosaccharomyces pombe|chr
2|||Manual
Length = 534
Score = 26.2 bits (55), Expect = 5.0
Identities = 16/50 (32%), Positives = 24/50 (48%)
Frame = -1
Query: 279 ASFELPESISIVIPSSRSAFSLSNTQAYLKDPLPISWASFSNFSMVRLSI 130
A+ +LP S S P+S S + L DP +S A + + V +SI
Sbjct: 110 ATSQLPSSTSFFSPTSSEYTPSSTESSSLLDPSSVSSAILPSSTSVEVSI 159
>SPAC1B3.04c |||mitochondrial GTPase Guf1 |Schizosaccharomyces
pombe|chr 1|||Manual
Length = 646
Score = 26.2 bits (55), Expect = 5.0
Identities = 21/65 (32%), Positives = 30/65 (46%)
Frame = +2
Query: 56 NIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERE 235
N VI H+D GKST + ++ G I++ + F LDKL+ ER
Sbjct: 60 NWAVIAHIDHGKSTLSDCILKLTGVINEHNF-----------RNQF-----LDKLEVERR 103
Query: 236 LGITI 250
GIT+
Sbjct: 104 RGITV 108
>SPCC70.08c |||methyltransferase |Schizosaccharomyces pombe|chr
3|||Manual
Length = 260
Score = 25.8 bits (54), Expect = 6.6
Identities = 11/29 (37%), Positives = 18/29 (62%)
Frame = +2
Query: 212 DKLKAERELGITIDMLSGSSKLASTMLPS 298
D +KA RELG+ ++ G L ++ +PS
Sbjct: 66 DMIKAARELGLNAYVIPGEKLLDASEIPS 94
>SPAC1687.08 |||sequence orphan|Schizosaccharomyces pombe|chr
1|||Manual
Length = 96
Score = 25.8 bits (54), Expect = 6.6
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = -1
Query: 342 CDHVLDEISVSRSXNDGNIVLASFELPESI 253
CDH+L IS SR G + FEL +I
Sbjct: 23 CDHLLQYISNSRDSKAGLKIFLVFELAVTI 52
>SPBC146.14c |sec26|SPBC337.01c|coatomer beta subunit
|Schizosaccharomyces pombe|chr 2|||Manual
Length = 940
Score = 25.4 bits (53), Expect = 8.7
Identities = 13/40 (32%), Positives = 21/40 (52%)
Frame = -1
Query: 336 HVLDEISVSRSXNDGNIVLASFELPESISIVIPSSRSAFS 217
+ +D+ SV R N + + ELPE ++ + R AFS
Sbjct: 607 YTIDDDSVERIMNCIRAIYSFEELPEFQTVFLDDMRKAFS 646
>SPAC8F11.09c |nnt1||nicotinamide N-methyltransferase Nnt1
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 255
Score = 25.4 bits (53), Expect = 8.7
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = -1
Query: 561 LSMRILPSDSSIWAHCMVFSGIHFVNSYDELFDT 460
+ +R++ S S +WAH + SGI N D+ DT
Sbjct: 42 IKLRLVGSHS-LWAHYLWNSGIELANYIDKNPDT 74
Database: spombe
Posted date: Oct 4, 2007 10:57 AM
Number of letters in database: 2,362,478
Number of sequences in database: 5004
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 2,761,949
Number of Sequences: 5004
Number of extensions: 53113
Number of successful extensions: 180
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 179
length of database: 2,362,478
effective HSP length: 71
effective length of database: 2,007,194
effective search space used: 355273338
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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