Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0247
(758 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 115 1e-24
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 111 2e-23
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 103 6e-21
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 101 1e-20
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 101 2e-20
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 100 4e-20
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 100 8e-20
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 95 1e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 95 2e-18
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 94 3e-18
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 94 4e-18
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 94 4e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 94 4e-18
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 5e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 93 9e-18
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 2e-17
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 91 4e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 4e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 90 5e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 90 6e-17
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 87 4e-16
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 86 1e-15
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 86 1e-15
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 84 4e-15
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 84 4e-15
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 1e-14
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 3e-14
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 81 3e-14
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 80 7e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 79 1e-13
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 76 8e-13
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 75 2e-12
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 74 4e-12
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 1e-11
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 72 2e-11
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 68 2e-10
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 66 9e-10
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 65 2e-09
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 65 2e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 63 8e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 62 1e-08
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 1e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 51 4e-05
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 48 2e-04
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 43 0.007
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 40 0.067
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 36 0.82
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 36 0.82
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 36 1.1
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 36 1.1
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 36 1.4
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 36 1.4
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 35 1.9
UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN domain-cont... 35 2.5
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 34 3.3
UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1; ... 34 4.4
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 34 4.4
UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chai... 34 4.4
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 115 bits (277), Expect = 1e-24
Identities = 56/76 (73%), Positives = 65/76 (85%)
Frame = +2
Query: 5 GXLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGG 184
G LAL SVSDKTGL+ A++L+ GL L+ASGGTA ALR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 185 RVKTLHPAVHAGILAR 232
RVKTLHPAVHAGILAR
Sbjct: 64 RVKTLHPAVHAGILAR 79
Score = 92.3 bits (219), Expect = 1e-17
Identities = 42/74 (56%), Positives = 52/74 (70%)
Frame = +2
Query: 455 SQRNQREQTSSDDFGHKARLALKAFTHTSDYDLAISDYFRKQYSPGQAQLTLRYGMNPHQ 634
S Q ++ + +LALKAFTHT+ YD AISDYFRKQYS G +Q+ LRYGMNPHQ
Sbjct: 155 STEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQ 214
Query: 635 KPAQVFTTRDSLPI 676
PAQ++T + LPI
Sbjct: 215 TPAQLYTLQPKLPI 228
Score = 66.5 bits (155), Expect = 7e-10
Identities = 38/84 (45%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGS 420
M R + I CNLYPFV+TV+ P VTV +AVE IDIGGVTLLRA + T
Sbjct: 88 MARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCE 147
Query: 421 PSSVTRPTTML*SKKSKRTNIIRR 492
P +T + S +SK T++ R
Sbjct: 148 PEDYVVVSTEMQSSESKDTSLETR 171
Score = 41.5 bits (93), Expect = 0.022
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQ 509
KNH RVTVVC+P DY V E++ ++ T+L TR+
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRR 172
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 111 bits (267), Expect = 2e-23
Identities = 55/78 (70%), Positives = 63/78 (80%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTGL+ AK L + GL L+ASGGTA LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 194 TLHPAVHAGILARLSDSD 247
TLHPAVH GILAR S +D
Sbjct: 61 TLHPAVHGGILARKSPAD 78
Score = 69.3 bits (162), Expect = 1e-10
Identities = 33/47 (70%), Positives = 36/47 (76%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
M++ Y I VCNLYPFV+TVS P VTV DAVE IDIGGVTLLRA
Sbjct: 82 MEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/67 (44%), Positives = 39/67 (58%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQD*P*RRSLILRTMTSPYRTTSASN 581
KNH RVTVVCDPADY V +E++ + G+R D P R L + T PYRTTS +
Sbjct: 131 KNHARVTVVCDPADYPRVAEEMEGS-------GSR-DTPSRTRL---STTRPYRTTSGDS 179
Query: 582 TRPGKPN 602
+ P+
Sbjct: 180 SAVAFPS 186
Score = 38.3 bits (85), Expect = 0.20
Identities = 14/21 (66%), Positives = 18/21 (85%)
Frame = +2
Query: 614 YGMNPHQKPAQVFTTRDSLPI 676
YGMNPHQ PAQ++T R +LP+
Sbjct: 191 YGMNPHQAPAQLYTLRPALPL 211
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 103 bits (246), Expect = 6e-21
Identities = 55/83 (66%), Positives = 63/83 (75%), Gaps = 1/83 (1%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 187
LALLSVSDKTGL+ LA+SL E G QL++SGGTA AL AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 188 VKTLHPAVHAGILARLSDSDQEA 256
VKTLHP +H GILARL S+ A
Sbjct: 77 VKTLHPRIHGGILARLECSEDRA 99
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/39 (53%), Positives = 26/39 (66%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
I V N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 109 IQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 101 bits (243), Expect = 1e-20
Identities = 53/83 (63%), Positives = 63/83 (75%), Gaps = 1/83 (1%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 187
LALLSVSDKTGL+ LA++L E G QL++SGGTA AL AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 188 VKTLHPAVHAGILARLSDSDQEA 256
VKTLHP +H GILARL + A
Sbjct: 69 VKTLHPRIHGGILARLERREDRA 91
Score = 44.4 bits (100), Expect = 0.003
Identities = 21/39 (53%), Positives = 26/39 (66%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
I V N YPF QTV++ V++ +A E IDIGG TL RA
Sbjct: 101 IQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARA 139
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 101 bits (242), Expect = 2e-20
Identities = 51/82 (62%), Positives = 65/82 (79%), Gaps = 1/82 (1%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTGL+ A+SL+ G++LI++GGTA A+ +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 194 TLHPAVHAGILA-RLSDSDQEA 256
TLHP VH G+LA R +D EA
Sbjct: 71 TLHPKVHGGLLAIRGNDEHAEA 92
Score = 41.5 bits (93), Expect = 0.022
Identities = 21/48 (43%), Positives = 27/48 (56%)
Frame = +1
Query: 253 SMKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+MK I V NLYPF TV + +D +ENIDIGG ++RA
Sbjct: 92 AMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
Score = 36.7 bits (81), Expect = 0.62
Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFR---KQYSP------GQAQLTLRYGMNPHQKPA 643
+ RLA KA+ T+ YD AIS++F + +P G+ +LRYG NPHQ A
Sbjct: 174 RRRLAAKAYARTAAYDAAISNWFAATIQNDAPDYRAFGGRLIQSLRYGENPHQHAA 229
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 100 bits (239), Expect = 4e-20
Identities = 47/78 (60%), Positives = 60/78 (76%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTGL+ LA++L ++L+++GGTAT +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP VH G+L R D
Sbjct: 71 TLHPMVHGGLLGRAGIDD 88
Score = 48.0 bits (109), Expect = 3e-04
Identities = 22/47 (46%), Positives = 29/47 (61%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
M + I + NLYPF Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 91 MAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 99.5 bits (237), Expect = 8e-20
Identities = 47/81 (58%), Positives = 63/81 (77%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTGL A +LS+ G++L+++GGT AL AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 194 TLHPAVHAGILARLSDSDQEA 256
TLHPAVH G+LA + + +A
Sbjct: 120 TLHPAVHGGLLAVRDNPEHQA 140
Score = 38.3 bits (85), Expect = 0.20
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
I V NLYPF +T+ K D VENID+GG ++RA
Sbjct: 150 IDLLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRA 187
Score = 35.5 bits (78), Expect = 1.4
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 10/57 (17%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFR----KQYSP------GQAQLTLRYGMNPHQKPA 643
+ RLA KAF+ T+ YD AI+++ + +P G +LRYG NPHQ A
Sbjct: 223 RRRLAQKAFSRTASYDAAIANWLAEVEGRDKAPTFKALGGTLAQSLRYGENPHQSAA 279
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 95.5 bits (227), Expect = 1e-18
Identities = 45/78 (57%), Positives = 58/78 (74%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDK G++ A++LS+ G++L+++GGTA L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP VH GIL R D
Sbjct: 70 TLHPKVHGGILGRRGQDD 87
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/49 (53%), Positives = 35/49 (71%)
Frame = +1
Query: 250 GSMKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
G M + + I V NLYPF QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 88 GIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 95.1 bits (226), Expect = 2e-18
Identities = 46/73 (63%), Positives = 57/73 (78%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 194 TLHPAVHAGILAR 232
TLHP VH GILAR
Sbjct: 66 TLHPKVHGGILAR 78
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/57 (50%), Positives = 36/57 (63%), Gaps = 3/57 (5%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR---TTTGSPSSVTRP 441
I V NLYPF TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
Score = 37.9 bits (84), Expect = 0.27
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 19/75 (25%)
Frame = +2
Query: 476 QTSSDDFGHKAR--LALKAFTHTSDYDLAISDYF-----------RKQYSPGQAQL---- 604
+ +++ +K R LA+KAFTHT+ YD AIS++ KQ P + QL
Sbjct: 163 KANANTLSYKTRFALAVKAFTHTARYDSAISNHLTALVTNDAGDVSKQAYPERFQLAFDK 222
Query: 605 --TLRYGMNPHQKPA 643
LRYG NPHQ A
Sbjct: 223 VQNLRYGENPHQSAA 237
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 94.3 bits (224), Expect = 3e-18
Identities = 51/82 (62%), Positives = 61/82 (74%), Gaps = 2/82 (2%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGR 187
LALLSVSDK+G++ LA+ L +E LI+SGGTA L+ AG+ V VSD T APE+LGGR
Sbjct: 4 LALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGGR 63
Query: 188 VKTLHPAVHAGILARLS-DSDQ 250
VKTLHP +H GILAR SDQ
Sbjct: 64 VKTLHPRIHGGILARRDLPSDQ 85
Score = 54.4 bits (125), Expect = 3e-06
Identities = 24/35 (68%), Positives = 29/35 (82%)
Frame = +1
Query: 292 VCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
V NLYPF QT++KP VTVA+AVE IDIGG ++RA
Sbjct: 100 VVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134
Score = 33.1 bits (72), Expect = 7.7
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFR-------KQYS-PGQAQLTLRYGMNPHQKPAQVFTT 658
+ + A +AF T+ YD AI++YF Q+ G + LRYG NPHQ T
Sbjct: 169 RQQFAGEAFALTNAYDQAIANYFSGLSGDSANQFGLSGTLRQPLRYGENPHQSAGWYQTG 228
Query: 659 RDS 667
R++
Sbjct: 229 REA 231
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 93.9 bits (223), Expect = 4e-18
Identities = 46/80 (57%), Positives = 56/80 (70%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 190
L L SVSDKTGL A L G IASGGTA L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 191 KTLHPAVHAGILARLSDSDQ 250
KTLHP +H GILAR + D+
Sbjct: 63 KTLHPMIHGGILARDTKEDR 82
Score = 57.2 bits (132), Expect = 4e-07
Identities = 25/47 (53%), Positives = 32/47 (68%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+K + I + NLYPF +T+S PD T +D +ENIDIGGV LLRA
Sbjct: 85 LKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 41.1 bits (92), Expect = 0.029
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTR 506
KN+ RVTV+CDPADYD V EI++ +L R
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIEKTGEISLSLRKR 168
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 93.9 bits (223), Expect = 4e-18
Identities = 44/76 (57%), Positives = 59/76 (77%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK GL+ AK+L + G+++I++GGTA L +AG+ V+ VSD+T PE+LGGRVK
Sbjct: 6 ALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILGGRVK 65
Query: 194 TLHPAVHAGILARLSD 241
TLHP + GILA L D
Sbjct: 66 TLHPKIFGGILADLGD 81
Score = 39.9 bits (89), Expect = 0.067
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEI 467
KNH V VVCDPADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
Score = 37.5 bits (83), Expect = 0.36
Identities = 23/42 (54%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Frame = +1
Query: 274 EXISXXVCNLYPFVQTVSKP-DVTVADAVENIDIGGVTLLRA 396
E I V NLYPF + K D V +ENIDIGGV LLRA
Sbjct: 94 EPIDLVVVNLYPFDEVQKKTRDEDVL--IENIDIGGVALLRA 133
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 93.9 bits (223), Expect = 4e-18
Identities = 42/79 (53%), Positives = 58/79 (73%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTG++ A+ L G+++I++GGTA LR+A + V DVS++T PEM+GGRVK
Sbjct: 5 ALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGRVK 64
Query: 194 TLHPAVHAGILARLSDSDQ 250
TLHP +H G+L +Q
Sbjct: 65 TLHPRIHGGLLCLRESKEQ 83
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/45 (48%), Positives = 30/45 (66%)
Frame = +1
Query: 262 RQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
++ I NLYPF TVS+ +V + +A+ENIDIGG TLLR+
Sbjct: 89 KEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
Score = 38.3 bits (85), Expect = 0.20
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 7/52 (13%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFRKQYSPGQA-------QLTLRYGMNPHQK 637
+A LA+KAF HT+DYD AI Y + + + LRYG N HQK
Sbjct: 168 RAELAVKAFRHTADYDAAIDTYLSRTLLGEEVLHLKFADGVKLRYGENWHQK 219
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 93.5 bits (222), Expect = 5e-18
Identities = 45/79 (56%), Positives = 58/79 (73%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 190
LALLSV DKTG+L LA++L + +++SGGTA ALR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 191 KTLHPAVHAGILARLSDSD 247
KTLHP VH G+L R D
Sbjct: 63 KTLHPKVHGGLLGRRGIDD 81
Score = 41.5 bits (93), Expect = 0.022
Identities = 26/55 (47%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFR---KQYSPGQAQ-----LTLRYGMNPHQKPA 643
K RLA KAFT T+ YD AIS+Y K++ LRYG NPHQK A
Sbjct: 163 KLRLATKAFTRTAAYDAAISNYLNGIDKEFPDVYTMQFGNGRKLRYGENPHQKAA 217
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 92.7 bits (220), Expect = 9e-18
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GRVK
Sbjct: 5 ALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGRVK 64
Query: 194 TLHPAVHAGILAR 232
TLHPA+H GILAR
Sbjct: 65 TLHPAIHGGILAR 77
Score = 37.1 bits (82), Expect = 0.47
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 13/77 (16%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFRKQYSPGQAQL------------TLRYGMNPHQKPAQ 646
+ RLA KA+ HTS+YD AI+ Y + QL +RYG NPHQ P
Sbjct: 161 RRRLAAKAYRHTSEYDAAITAYLSGESDELPTQLPEHLSLDLTRTAQVRYGENPHQ-PGA 219
Query: 647 VFTTRDSL-PIHDTETV 694
++ ++ P+ D + V
Sbjct: 220 IYRWGNARGPVIDAQVV 236
Score = 36.7 bits (81), Expect = 0.62
Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Frame = +1
Query: 250 GSMKRQKYEXISXXVCNLYPFVQTVSK--PDVTVADAVENIDIGGVTLLRA 396
G + Q I NLYPF +TV++ PD V +ENIDIGG ++R+
Sbjct: 84 GQLAAQDIGTIDLVCVNLYPFRETVARGAPDPEV---IENIDIGGPAMIRS 131
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 91.5 bits (217), Expect = 2e-17
Identities = 42/73 (57%), Positives = 55/73 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+S+SDKT L L L E G ++++GGT++AL AG++V V ++TR PEML GRVK
Sbjct: 91 ALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEMLDGRVK 150
Query: 194 TLHPAVHAGILAR 232
TLHP+VH GILAR
Sbjct: 151 TLHPSVHGGILAR 163
Score = 44.4 bits (100), Expect = 0.003
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 10/63 (15%)
Frame = +2
Query: 485 SDDFGHKARLALKAFTHTSDYDLAISDYFRKQ-----YSPG-----QAQLTLRYGMNPHQ 634
+DD + +LA KAF H + YD A+S++ KQ + PG + LRYG NPHQ
Sbjct: 248 NDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFPPGLTVPLHLKSLLRYGENPHQ 307
Query: 635 KPA 643
K A
Sbjct: 308 KAA 310
Score = 38.7 bits (86), Expect = 0.15
Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +1
Query: 253 SMKRQKYEXISXXVCNLYPFVQTVSKPD-VTVADAVENIDIGGVTLLRA 396
++++ + V NLYPF VS ++ D +ENIDIGG ++RA
Sbjct: 172 ALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 90.6 bits (215), Expect = 4e-17
Identities = 43/73 (58%), Positives = 56/73 (76%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV DKTG+L LAK L G ++++SGGT T L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 194 TLHPAVHAGILAR 232
TLHPA+H GIL R
Sbjct: 63 TLHPAIHGGILFR 75
Score = 34.7 bits (76), Expect = 2.5
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 11/77 (14%)
Frame = +2
Query: 512 LALKAFTHTSDYDLAISDYFRKQYS-----------PGQAQLTLRYGMNPHQKPAQVFTT 658
LALKAF TS YD I+ YF K + P + LRYG NPHQ+ A ++
Sbjct: 167 LALKAFWLTSYYDAVIASYFSKVFGFSEKDFKHHTVPMFLRDELRYGENPHQQ-AYLYEN 225
Query: 659 RDSLPIHDTETVRLDFI 709
P+ + VR D +
Sbjct: 226 ----PLEENGIVRADVL 238
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 90.6 bits (215), Expect = 4e-17
Identities = 42/72 (58%), Positives = 55/72 (76%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV DKTGL LAK L E G++++++G TA + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 194 TLHPAVHAGILA 229
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/41 (48%), Positives = 24/41 (58%)
Frame = +1
Query: 274 EXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
E V NLYPFV+TV K D VE IDIGG ++R+
Sbjct: 102 EAFDLVVVNLYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
Score = 36.3 bits (80), Expect = 0.82
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 16/67 (23%)
Frame = +2
Query: 491 DFGHKARLALKAFTHTSDYDLAISDYFRKQYS----------PGQAQL------TLRYGM 622
D + RLA KAF HT+ YD A++ + Q+ P A L LRYG
Sbjct: 171 DLKTRQRLAAKAFAHTASYDTAVATWTASQFLDEDGDGVIDWPAYAGLALERSEVLRYGE 230
Query: 623 NPHQKPA 643
NPHQ+ A
Sbjct: 231 NPHQQAA 237
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 90.2 bits (214), Expect = 5e-17
Identities = 39/71 (54%), Positives = 54/71 (76%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDKTG++ A L ++++++GGTA LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 194 TLHPAVHAGIL 226
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/48 (41%), Positives = 31/48 (64%)
Frame = +1
Query: 253 SMKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
SM+ E I V +LYPF +T+ V++A+A+E IDIGG ++R+
Sbjct: 96 SMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 89.8 bits (213), Expect = 6e-17
Identities = 43/73 (58%), Positives = 55/73 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSV +K+G++ +K LS G LI++GGTA +L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 194 TLHPAVHAGILAR 232
TLHP +H G+LAR
Sbjct: 63 TLHPKIHGGLLAR 75
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/47 (55%), Positives = 34/47 (72%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+ + + IS V NLYPFV+TVSK T+ +A+ENIDIGG TL+RA
Sbjct: 85 LNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 87.0 bits (206), Expect = 4e-16
Identities = 42/84 (50%), Positives = 59/84 (70%), Gaps = 1/84 (1%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK G++ A+ L++ G ++I++GGT AL AG+T + D+T PEM+ GRVK
Sbjct: 5 ALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGRVK 64
Query: 194 TLHPAVHAGILARLS-DSDQEA*N 262
TLHP +H G+LAR DS +A N
Sbjct: 65 TLHPKIHGGLLARRDLDSHLQAAN 88
Score = 50.0 bits (114), Expect = 6e-05
Identities = 23/39 (58%), Positives = 29/39 (74%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
I V NLYPF +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 95 IDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
Score = 41.1 bits (92), Expect = 0.029
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Frame = +2
Query: 494 FGHKARLALKAFTHTSDYDLAISDYFRKQYSPGQAQ-LTLRYGMN 625
+ + RLA K F HT+ YD I+DYF KQ + + LT+ Y +N
Sbjct: 165 YATRQRLAAKVFRHTAAYDALIADYFTKQVGEDKPEKLTITYDLN 209
Score = 37.9 bits (84), Expect = 0.27
Identities = 20/36 (55%), Positives = 23/36 (63%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQ 509
KNH VTVV DPADY V+ EI E +T+ TRQ
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAE--QGETSYATRQ 169
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 86.6 bits (205), Expect = 6e-16
Identities = 37/78 (47%), Positives = 55/78 (70%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDKT ++ AK L E G +++++GGT ++ AG+ V V ++T PEML GRVK
Sbjct: 5 ALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGRVK 64
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP +H G+L + S+ +
Sbjct: 65 TLHPMIHGGLLGKRSNHE 82
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/47 (48%), Positives = 30/47 (63%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
M+ I NLYPF +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 87 MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
Score = 41.5 bits (93), Expect = 0.022
Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Frame = +2
Query: 479 TSSDDFGHKARLALKAFTHTSDYDLAISDYFRKQYS---PGQAQLT------LRYGMNPH 631
+ +D + + +LA K F HT+ YD I++YF Q P +T LRYG NPH
Sbjct: 159 SETDTYEFRQQLAAKVFRHTASYDAMIANYFLSQTEEQYPESYTVTYEKVQDLRYGENPH 218
Query: 632 QKPA 643
Q+ A
Sbjct: 219 QQAA 222
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 86.6 bits (205), Expect = 6e-16
Identities = 43/78 (55%), Positives = 54/78 (69%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTG++ A+ L + G++L+++GGTA L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP VH GIL R D
Sbjct: 69 TLHPKVHGGILGRRGTDD 86
Score = 61.3 bits (142), Expect = 3e-08
Identities = 28/47 (59%), Positives = 35/47 (74%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
M++ E I V NLYPF TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 89 MQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/72 (55%), Positives = 54/72 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSV+DK+GL+ A L++ G++L+++GGT L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 194 TLHPAVHAGILA 229
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 85.8 bits (203), Expect = 1e-15
Identities = 38/78 (48%), Positives = 54/78 (69%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDK G++ K L G +++++GGT L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP +H GIL + SD +
Sbjct: 63 TLHPKIHGGILHKRSDEN 80
Score = 39.1 bits (87), Expect = 0.12
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 9/61 (14%)
Frame = +2
Query: 488 DDFGHKARLALKAFTHTSDYDLAISDYFRKQYS---------PGQAQLTLRYGMNPHQKP 640
+D + L +KA+ HT++YD I++Y ++++ GQ +YG NPHQK
Sbjct: 159 NDENFRLNLMIKAYEHTANYDAYIANYMNERFNGGFGASKFIVGQKVFDTKYGENPHQKG 218
Query: 641 A 643
A
Sbjct: 219 A 219
Score = 33.1 bits (72), Expect = 7.7
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +1
Query: 292 VC-NLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
VC NLYPF +T D + +ENIDIGG ++R+
Sbjct: 96 VCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 85.4 bits (202), Expect = 1e-15
Identities = 39/72 (54%), Positives = 54/72 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GRVK
Sbjct: 19 ALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGRVK 78
Query: 194 TLHPAVHAGILA 229
TLHP +H+GILA
Sbjct: 79 TLHPFIHSGILA 90
Score = 39.1 bits (87), Expect = 0.12
Identities = 22/50 (44%), Positives = 30/50 (60%)
Frame = +1
Query: 292 VCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPSSVTRP 441
VCNLYPF TV+ + + VE IDIGG +++RA + S + VT P
Sbjct: 113 VCNLYPFQDTVAS-GASFDECVEQIDIGGPSMVRAAAKNHP-SVAVVTSP 160
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 85.0 bits (201), Expect = 2e-15
Identities = 40/73 (54%), Positives = 55/73 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
A++SV K G+ LAK+L E G +++++GGTA LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 194 TLHPAVHAGILAR 232
TLHP VH GIL R
Sbjct: 63 TLHPVVHGGILFR 75
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/55 (45%), Positives = 31/55 (56%), Gaps = 10/55 (18%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYFRKQYS----------PGQAQLTLRYGMNPHQK 637
+A LA KAF+HT+ YD IS F+K YS P + LRYG NPHQ+
Sbjct: 164 RAYLAWKAFSHTAYYDGVISQAFKKLYSIDTFGKEEALPLKRMQKLRYGENPHQR 218
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 84.6 bits (200), Expect = 2e-15
Identities = 39/72 (54%), Positives = 54/72 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
A+LSVS+KTG++ AK+L++ +L ++GGT L A + V+ VSD+T PE++ GRVK
Sbjct: 4 AILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVK 63
Query: 194 TLHPAVHAGILA 229
TLHPAVH GILA
Sbjct: 64 TLHPAVHGGILA 75
Score = 60.1 bits (139), Expect = 6e-08
Identities = 27/47 (57%), Positives = 34/47 (72%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+ Q + I V NLYPF QTV+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 86 LSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
Score = 38.3 bits (85), Expect = 0.20
Identities = 24/63 (38%), Positives = 34/63 (53%)
Frame = +2
Query: 470 REQTSSDDFGHKARLALKAFTHTSDYDLAISDYFRKQYSPGQAQLTLRYGMNPHQKPAQV 649
R + S D ++ L +K F HT++YD AI +F+ G + TLRYG NP Q V
Sbjct: 155 RLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFK-----GDKE-TLRYGENPQQSAYFV 208
Query: 650 FTT 658
T+
Sbjct: 209 RTS 211
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 83.8 bits (198), Expect = 4e-15
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSV DKTG++ LA++L + +++SGGT TAL AG+ +VS T PEM+ GRVK
Sbjct: 34 ALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGRVK 93
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP VH G+L R D
Sbjct: 94 TLHPKVHGGLLGRRQIDD 111
Score = 37.9 bits (84), Expect = 0.27
Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 10/70 (14%)
Frame = +2
Query: 479 TSSDDFGHKARL--ALKAFTHTSDYDLAISDYFRKQYSPGQAQLTL--------RYGMNP 628
+S+ F H+ RL A KAF T+ YD AIS++ + LTL RYG NP
Sbjct: 184 SSNVGFSHEQRLIFAKKAFARTAAYDAAISNHLSNLDNTFPPILTLQFTNGRMLRYGENP 243
Query: 629 HQKPAQVFTT 658
HQ+ A TT
Sbjct: 244 HQQAAVYGTT 253
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 83.8 bits (198), Expect = 4e-15
Identities = 41/72 (56%), Positives = 54/72 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV DK G+L LAK L + +++I+SGGT L+ + V+++S+IT PEML GRVK
Sbjct: 5 ALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGRVK 64
Query: 194 TLHPAVHAGILA 229
TLHP VHAGILA
Sbjct: 65 TLHPLVHAGILA 76
Score = 40.3 bits (90), Expect = 0.050
Identities = 20/48 (41%), Positives = 31/48 (64%)
Frame = +1
Query: 253 SMKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+++ ++ I V NLYPF + V + D++ + VE IDIGG T+LRA
Sbjct: 86 TLEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 82.6 bits (195), Expect = 1e-14
Identities = 40/73 (54%), Positives = 54/73 (73%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 194 TLHPAVHAGILAR 232
TLH + AGIL+R
Sbjct: 70 TLHHKICAGILSR 82
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 81.4 bits (192), Expect = 2e-14
Identities = 39/76 (51%), Positives = 56/76 (73%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK L SL + L++ ++LI+SGGT ++ Q+VS+ T +PE+LGGRVK
Sbjct: 14 ALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGRVK 73
Query: 194 TLHPAVHAGILARLSD 241
TLHP +HAGIL++ +D
Sbjct: 74 TLHPKIHAGILSKRND 89
Score = 39.9 bits (89), Expect = 0.067
Identities = 17/47 (36%), Positives = 29/47 (61%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+K +Y+ I + N YPF +T+ + + +ENID+GG T++RA
Sbjct: 96 LKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRA 141
Score = 38.3 bits (85), Expect = 0.20
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 9/77 (11%)
Frame = +2
Query: 503 KARLALKAFTHTSDYDLAISDYF---------RKQYSPGQAQLTLRYGMNPHQKPAQVFT 655
+ +++L+AF+ T+ YD IS+YF +K+ G LRYG NPHQ+ A +++
Sbjct: 177 REKMSLEAFSETAYYDAVISNYFNKIKKNNFPKKKIIYGNLIEKLRYGENPHQE-AAIYS 235
Query: 656 TRDSLPIHDTETVRLDF 706
+L I +L +
Sbjct: 236 KTQNLNIKQIHGKQLSY 252
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 81.0 bits (191), Expect = 3e-14
Identities = 38/73 (52%), Positives = 50/73 (68%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GRVK
Sbjct: 14 ALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGRVK 73
Query: 194 TLHPAVHAGILAR 232
TLHP +HAG+LAR
Sbjct: 74 TLHPKIHAGLLAR 86
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/48 (47%), Positives = 32/48 (66%)
Frame = +1
Query: 253 SMKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
++ + + I V NLYPFVQTVS + ++ AVE IDIGG ++LRA
Sbjct: 93 TLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRA 140
Score = 38.7 bits (86), Expect = 0.15
Identities = 19/36 (52%), Positives = 24/36 (66%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQ 509
KN VTVV DP DY +++EIK + H TTL TR+
Sbjct: 143 KNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRK 177
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 81.0 bits (191), Expect = 3e-14
Identities = 37/76 (48%), Positives = 55/76 (72%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK+GL+ AK L++ G+++I++GGT L++ G+ + D T PE+L GRVK
Sbjct: 7 ALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGRVK 66
Query: 194 TLHPAVHAGILARLSD 241
TLHP VH G+L +S+
Sbjct: 67 TLHPKVHGGLLGVISN 82
Score = 55.6 bits (128), Expect = 1e-06
Identities = 24/47 (51%), Positives = 35/47 (74%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
M+ K I V NLYPF++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 89 MEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
Score = 40.3 bits (90), Expect = 0.050
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 12/68 (17%)
Frame = +2
Query: 521 KAFTHTSDYDLAISDYFRKQYS---PGQAQLT------LRYGMNPHQKPA---QVFTTRD 664
KAF+HT+ YD AIS +F KQ P L+ LRYG NPHQ + +FT D
Sbjct: 175 KAFSHTAMYDAAISSWFYKQSGEVFPDVLNLSFIKKQKLRYGENPHQAASFYEPLFTKSD 234
Query: 665 SLPIHDTE 688
P+ E
Sbjct: 235 FSPLQGKE 242
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 79.8 bits (188), Expect = 7e-14
Identities = 35/72 (48%), Positives = 53/72 (73%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDKT L+ K L+E G+++I++GGT L+ G+ V +S++T PE++ GR+K
Sbjct: 6 ALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGRLK 65
Query: 194 TLHPAVHAGILA 229
TLHP +H G+LA
Sbjct: 66 TLHPNIHGGLLA 77
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/41 (58%), Positives = 30/41 (73%)
Frame = +1
Query: 274 EXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+ I V NLYPF +T+SK DVT +A+ENIDIGG +LRA
Sbjct: 94 QPIDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 41.5 bits (93), Expect = 0.022
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 9/67 (13%)
Frame = +2
Query: 464 NQREQTSSDDFGHKARLALKAFTHTSDYDLAISDYFRK---QYSPGQAQLT------LRY 616
NQ ++ S K LA K F HT+ YD I+DY + P Q +T LRY
Sbjct: 156 NQIKEEGSVSLQKKRELAAKVFRHTAAYDALIADYLTNVVGEKEPEQFTVTFEKKQSLRY 215
Query: 617 GMNPHQK 637
G NPHQ+
Sbjct: 216 GENPHQE 222
Score = 37.1 bits (82), Expect = 0.47
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +3
Query: 402 KNHDRVTVVCDPADYDAVVKEIKE 473
KNH VTV+ DPADY V+ +IKE
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE 160
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 79.0 bits (186), Expect = 1e-13
Identities = 36/72 (50%), Positives = 54/72 (75%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GRVK
Sbjct: 10 ALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGRVK 69
Query: 194 TLHPAVHAGILA 229
TLHP +HA ILA
Sbjct: 70 TLHPKIHAPILA 81
Score = 39.1 bits (87), Expect = 0.12
Identities = 17/41 (41%), Positives = 23/41 (56%)
Frame = +1
Query: 292 VCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTT 414
V NLYPF + + +D +E IDIGG L+RA + T
Sbjct: 104 VVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHT 144
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 76.2 bits (179), Expect = 8e-13
Identities = 36/78 (46%), Positives = 54/78 (69%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV K G+ LA++ + G +++++G TA L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 194 TLHPAVHAGILARLSDSD 247
TLHP +HAGILA +++ +
Sbjct: 71 TLHPYIHAGILADMTNPE 88
Score = 36.3 bits (80), Expect = 0.82
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 292 VCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 393
V NLYPF TV + AD +E IDIGG +++R
Sbjct: 105 VVNLYPFADTV-RSGANEADTIEKIDIGGPSMVR 137
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 74.9 bits (176), Expect = 2e-12
Identities = 39/79 (49%), Positives = 55/79 (69%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDK+ L LA+ L ++++++GGT AL G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 194 TLHPAVHAGILARLSDSDQ 250
TLHP +H GILA +++ Q
Sbjct: 77 TLHPKIHGGILALPTEAHQ 95
Score = 52.8 bits (121), Expect = 9e-06
Identities = 22/39 (56%), Positives = 30/39 (76%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
I + NLYPF +T++KP + ADA+ENIDIGG T++RA
Sbjct: 106 IDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRA 144
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 73.7 bits (173), Expect = 4e-12
Identities = 36/72 (50%), Positives = 49/72 (68%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SVSDKTG+ SLAK+L + ++LI + GT L G+ VS+ PE++ GRVK
Sbjct: 11 ALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGRVK 70
Query: 194 TLHPAVHAGILA 229
TLHP +H GIL+
Sbjct: 71 TLHPKIHGGILS 82
Score = 41.5 bits (93), Expect = 0.022
Identities = 17/46 (36%), Positives = 27/46 (58%)
Frame = +1
Query: 259 KRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
K + I + N YPF + V K ++ + + ++NIDIGGV L R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 72.5 bits (170), Expect = 1e-11
Identities = 34/73 (46%), Positives = 47/73 (64%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 194 TLHPAVHAGILAR 232
TLHP + GILAR
Sbjct: 71 TLHPMIFGGILAR 83
Score = 34.7 bits (76), Expect = 2.5
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 280 ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLR 393
I + +LYPF TV+ + D +E IDIGG++L+R
Sbjct: 101 IDLVIVDLYPFEATVAS-GASEEDIIEKIDIGGISLIR 137
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 71.7 bits (168), Expect = 2e-11
Identities = 39/78 (50%), Positives = 51/78 (65%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
ALLSVSDKTGLL LAK+L+ ++LIASGGTA AL AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 194 TLHPAVHAGILARLSDSD 247
T+ + + +L R D +
Sbjct: 67 TISFEIASSLLFRRQDEN 84
Score = 41.5 bits (93), Expect = 0.022
Identities = 22/41 (53%), Positives = 25/41 (60%)
Frame = +1
Query: 274 EXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
E I V NLYPF T+ K + +ENIDIGG TLLRA
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRA 134
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/80 (46%), Positives = 51/80 (63%)
Frame = +2
Query: 11 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRV 190
LA+L+VSDK + LA L G ++A+ GT LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 191 KTLHPAVHAGILARLSDSDQ 250
KTL ++ GILAR +D+
Sbjct: 62 KTLTVSLMGGILARDEPADR 81
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 66.1 bits (154), Expect = 9e-10
Identities = 34/80 (42%), Positives = 49/80 (61%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+SV K GL + L E G++ +++GGT + + G + V D+T P +LGGRVK
Sbjct: 10 ALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGRVK 69
Query: 194 TLHPAVHAGILARLSDSDQE 253
TLHP + GIL R D +Q+
Sbjct: 70 TLHPKIFGGILCR-RDLEQD 88
Score = 40.3 bits (90), Expect = 0.050
Identities = 21/46 (45%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Frame = +1
Query: 265 QKYEX--ISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+KYE I + +LYPF TV+ + AD +E IDIGG++L+RA
Sbjct: 93 EKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRA 137
Score = 33.1 bits (72), Expect = 7.7
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Frame = +2
Query: 473 EQTSSDDFGHKARLALKAFTHTSDYDLAISDYFRKQYSPG-----QAQLTLRYGMNPHQK 637
E ++ + +A +AF +S YD AI +YF Q LRYG NPHQK
Sbjct: 163 EHGATSSLEERRWMAKEAFAVSSHYDSAIFNYFDAGEGSAFRCSVNNQKQLRYGENPHQK 222
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/73 (43%), Positives = 45/73 (61%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++L G VK
Sbjct: 24 ALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVK 83
Query: 194 TLHPAVHAGILAR 232
TLHP + GIL R
Sbjct: 84 TLHPNIQGGILPR 96
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/73 (43%), Positives = 45/73 (61%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
AL+S+S+K L L SL G ++++ GGT AL NA ++ V +T P++L G VK
Sbjct: 24 ALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVK 83
Query: 194 TLHPAVHAGILAR 232
TLHP + GIL R
Sbjct: 84 TLHPNIQGGILPR 96
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 62.9 bits (146), Expect = 8e-09
Identities = 28/72 (38%), Positives = 47/72 (65%)
Frame = +2
Query: 17 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 196
L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR+KT
Sbjct: 11 LISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGRIKT 70
Query: 197 LHPAVHAGILAR 232
LH ++A ILA+
Sbjct: 71 LHHKIYASILAQ 82
Score = 35.5 bits (78), Expect = 1.4
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Frame = +1
Query: 265 QKYEXI--SXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+KY I V N YPF + + ++ + D +E+IDIGG ++RA
Sbjct: 91 EKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/80 (40%), Positives = 48/80 (60%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVK 193
A++SV DKT L LA L G+++I + GT L+ G+ ++D PE+LGGRVK
Sbjct: 6 AIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILGGRVK 65
Query: 194 TLHPAVHAGILARLSDSDQE 253
++ P + GILA+ +D E
Sbjct: 66 SIDPKLAGGILAKSNDKKHE 85
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/70 (45%), Positives = 44/70 (62%)
Frame = +2
Query: 17 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 196
L+S+ +K L + + L E G ++ AS GTA L++ G+ DVS IT +LGG VKT
Sbjct: 5 LVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKT 64
Query: 197 LHPAVHAGIL 226
LHP + AGIL
Sbjct: 65 LHPEIFAGIL 74
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 62.1 bits (144), Expect = 1e-08
Identities = 36/80 (45%), Positives = 51/80 (63%)
Frame = +2
Query: 17 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 196
L+SVSD +GL L + L+ + A+ GT L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 197 LHPAVHAGILARLSDSDQEA 256
LHPAV +GIL+R D EA
Sbjct: 61 LHPAVFSGILSR-RDEQSEA 79
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/47 (42%), Positives = 29/47 (61%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
+KR Y +CNLY F + K ++ D +ENIDIGG++L+RA
Sbjct: 81 LKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 50.8 bits (116), Expect = 4e-05
Identities = 26/47 (55%), Positives = 30/47 (63%)
Frame = +1
Query: 256 MKRQKYEXISXXVCNLYPFVQTVSKPDVTVADAVENIDIGGVTLLRA 396
MKR I V NLYPF QTV++PDVT A NIDIGG ++RA
Sbjct: 107 MKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRA 153
Score = 39.5 bits (88), Expect = 0.088
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Frame = +2
Query: 17 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATALRN-----AGLTVQDVSDITRAPEM 175
L+SVSDKTGL L + + ++GGT + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 176 LGGRVKTLHPAVHAGIL 226
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
Score = 35.1 bits (77), Expect = 1.9
Identities = 15/23 (65%), Positives = 18/23 (78%)
Frame = +2
Query: 512 LALKAFTHTSDYDLAISDYFRKQ 580
LA KAF HT+ YD AI+DY +KQ
Sbjct: 192 LAQKAFDHTAAYDRAIADYLKKQ 214
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.4 bits (110), Expect = 2e-04
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +2
Query: 17 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKT 196
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 197 LHPAVHAGILA 229
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -3
Query: 393 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQVTD 292
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 39.9 bits (89), Expect = 0.067
Identities = 24/67 (35%), Positives = 34/67 (50%)
Frame = -2
Query: 217 SMYRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKRRGGTATGNQLQATFRQALC*RE*TR 38
+M+ + P H R + DV H+L+ +A + R GG A G QL A RQ + T
Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTG 539
Query: 37 LV*NAEK 17
LV N E+
Sbjct: 540 LVGNGEE 546
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 36.3 bits (80), Expect = 0.82
Identities = 22/74 (29%), Positives = 34/74 (45%)
Frame = +2
Query: 32 DKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAV 211
DK + LA+ G +L+A+ GTA AG+T V + P L +++ H V
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIV 1007
Query: 212 HAGILARLSDSDQE 253
+ LSD+ E
Sbjct: 1008 MVVNITNLSDAASE 1021
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 36.3 bits (80), Expect = 0.82
Identities = 20/42 (47%), Positives = 24/42 (57%)
Frame = +2
Query: 32 DKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 157
DK ++LAK G QL+A+ GTATAL GL V V I
Sbjct: 946 DKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.9 bits (79), Expect = 1.1
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +2
Query: 17 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI-TRAPEML 178
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 35.9 bits (79), Expect = 1.1
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +2
Query: 173 MLGGRVKTLHPAVHAGILAR 232
ML G VKTLHP +H GILAR
Sbjct: 1 MLDGHVKTLHPNIHGGILAR 20
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.5 bits (78), Expect = 1.4
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +2
Query: 14 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATALRNAGL 133
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 35.5 bits (78), Expect = 1.4
Identities = 15/43 (34%), Positives = 30/43 (69%)
Frame = +2
Query: 29 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 157
SDK ++ K+L++ G++L+A+ GTA L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 35.1 bits (77), Expect = 1.9
Identities = 20/32 (62%), Positives = 21/32 (65%)
Frame = -3
Query: 393 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQV 298
AQ G AADVDVLD V L +RL ERVQV
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV 465
>UniRef50_UPI0000EB3B66 Cluster: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29).;
n=2; Canis lupus familiaris|Rep: Zinc finger and SCAN
domain-containing protein 20 (Zinc finger protein 31)
(Zinc finger protein 360) (Zinc finger protein KOX29). -
Canis familiaris
Length = 513
Score = 34.7 bits (76), Expect = 2.5
Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 8/100 (8%)
Frame = +1
Query: 64 PVGMWPAVDCQ--WRYRHGASERRPH-----SSRCVGHHESTGDARRSGEN-FTSSGTCW 219
P WP CQ WR ++ P VG E T +++ + F +G+CW
Sbjct: 187 PANHWPEAQCQKQWRLFFSSAVLTPRVPTLPKMGSVGDWEVTAESQEPNKTCFVRAGSCW 246
Query: 220 DLSSIIRL*PGSMKRQKYEXISXXVCNLYPFVQTVSKPDV 339
D S + R K+ E S V N + VSKP +
Sbjct: 247 DSSPLHRE-VQQRKQVNKENRSVKVGNQHSLGVPVSKPSI 285
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 34.7 bits (76), Expect = 2.5
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = -3
Query: 393 AQEGHAADVDVLDRVRHGHVRLRYRLDERVQV 298
A+ G AAD+DVLD + HG V R ERV+V
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEV 443
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 34.3 bits (75), Expect = 3.3
Identities = 22/47 (46%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Frame = +2
Query: 14 ALLSV--SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDV 148
ALLS+ DK LL +AK L G + A+ GTA AL+ AG+ Q V
Sbjct: 77 ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_Q2VZX1 Cluster: Putative uncharacterized protein; n=1;
Magnetospirillum magneticum AMB-1|Rep: Putative
uncharacterized protein - Magnetospirillum magneticum
(strain AMB-1 / ATCC 700264)
Length = 309
Score = 33.9 bits (74), Expect = 4.4
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Frame = +2
Query: 89 IASGGTATALRNAGLTVQDVSDITRAPEM-LGGRVKTLHPAVHAGILARLSD 241
+ + GT T RN+ TV+ SDIT A + +GG T+ A+ AG++ R +D
Sbjct: 58 VQNSGTITEARNSWGTVKTGSDITEASIVNIGGIETTIKAAMAAGMVTRNAD 109
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 33.9 bits (74), Expect = 4.4
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 32 DKTGLLSLAKSLSECGLQLIASGGTATALRN 124
DK GL+ +A+SL E G +L A+ GTA LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_Q8XZ83 Cluster: Carbamoyl-phosphate synthase large chain;
n=155; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 1081
Score = 33.9 bits (74), Expect = 4.4
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +2
Query: 29 SDKTGLLSLAKSLSECGLQLIASGGTATALRNAGLTVQDVSDI 157
SDK + +A++L G ++A+ GTA+A+ AG+ V+ V+ +
Sbjct: 960 SDKPRAIEVARTLHTLGYPIVATRGTASAIEAAGIPVRVVNKV 1002
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 697,383,782
Number of Sequences: 1657284
Number of extensions: 13785316
Number of successful extensions: 43471
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 41547
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43426
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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