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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbpv0226
         (754 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY312516-1|AAQ85132.1|  275|Homo sapiens alkaline ceramidase 2 p...   137   3e-32
AL391834-9|CAM21146.1|  275|Homo sapiens N-acylsphingosine amido...   137   3e-32
AL158206-4|CAH73022.1|  275|Homo sapiens N-acylsphingosine amido...   137   3e-32
BC112124-1|AAI12125.1|  264|Homo sapiens N-acylsphingosine amido...   109   1e-23
BC112122-1|AAI12123.1|  264|Homo sapiens N-acylsphingosine amido...   109   1e-23
AF347024-1|AAL83822.1|  264|Homo sapiens alkaline ceramidase pro...   109   1e-23
BC092487-1|AAH92487.1|  226|Homo sapiens ASAH3L protein protein.       98   3e-20
BC073853-1|AAH73853.1|  267|Homo sapiens phytoceramidase, alkali...    49   2e-05
AF327353-1|AAL56013.1|  267|Homo sapiens alkaline dihydroceramid...    49   2e-05
AF214454-1|AAK71923.1|  267|Homo sapiens alkaline phytoceramidas...    49   2e-05
BC114631-1|AAI14632.1|  339|Homo sapiens chromosome 6 open readi...    31   5.9  
BC114630-1|AAI14631.1|  339|Homo sapiens chromosome 6 open readi...    31   5.9  
AY164485-1|AAO32798.1| 1732|Homo sapiens polycystic kidney disea...    31   5.9  
AL390026-2|CAI20238.1|  339|Homo sapiens chromosome 6 open readi...    31   5.9  
AL031058-2|CAI21647.2|  339|Homo sapiens chromosome 6 open readi...    31   5.9  
BX537565-1|CAD97783.1|  461|Homo sapiens hypothetical protein pr...    30   7.8  
BC068556-1|AAH68556.1|  461|Homo sapiens solute carrier family 4...    30   7.8  
BC060850-1|AAH60850.1|  463|Homo sapiens SLC46A3 protein protein.      30   7.8  
BC036662-1|AAH36662.1|  461|Homo sapiens solute carrier family 4...    30   7.8  
AL359454-3|CAM24029.1|  461|Homo sapiens novel protein protein.        30   7.8  
AL359454-2|CAI17158.1|  463|Homo sapiens novel protein protein.        30   7.8  

>AY312516-1|AAQ85132.1|  275|Homo sapiens alkaline ceramidase 2
           protein.
          Length = 275

 Score =  137 bits (332), Expect = 3e-32
 Identities = 65/142 (45%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NY+I P IAEF NT+SN+LFF+ PP+ + LF++Y+  FN  I ++W LL++VG+ S YFH
Sbjct: 23  NYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFH 82

Query: 435 ATLSLVGQLLDELAILWVFMAAFAI-SCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLV 611
           ATLS +GQ+LDELA+LWV M A A+    +Y+ + F  + G +  +  SV S ++T    
Sbjct: 83  ATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVV-SVLSAVTTCLAF 141

Query: 612 MHPAANAFALMTLALPAMGFLV 677
           + PA N  +LMTL +P    L+
Sbjct: 142 VKPAINNISLMTLGVPCTALLI 163


>AL391834-9|CAM21146.1|  275|Homo sapiens N-acylsphingosine
           amidohydrolase 3-like protein.
          Length = 275

 Score =  137 bits (332), Expect = 3e-32
 Identities = 65/142 (45%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NY+I P IAEF NT+SN+LFF+ PP+ + LF++Y+  FN  I ++W LL++VG+ S YFH
Sbjct: 23  NYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFH 82

Query: 435 ATLSLVGQLLDELAILWVFMAAFAI-SCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLV 611
           ATLS +GQ+LDELA+LWV M A A+    +Y+ + F  + G +  +  SV S ++T    
Sbjct: 83  ATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVV-SVLSAVTTCLAF 141

Query: 612 MHPAANAFALMTLALPAMGFLV 677
           + PA N  +LMTL +P    L+
Sbjct: 142 VKPAINNISLMTLGVPCTALLI 163


>AL158206-4|CAH73022.1|  275|Homo sapiens N-acylsphingosine
           amidohydrolase 3-like protein.
          Length = 275

 Score =  137 bits (332), Expect = 3e-32
 Identities = 65/142 (45%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NY+I P IAEF NT+SN+LFF+ PP+ + LF++Y+  FN  I ++W LL++VG+ S YFH
Sbjct: 23  NYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFH 82

Query: 435 ATLSLVGQLLDELAILWVFMAAFAI-SCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLV 611
           ATLS +GQ+LDELA+LWV M A A+    +Y+ + F  + G +  +  SV S ++T    
Sbjct: 83  ATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVV-SVLSAVTTCLAF 141

Query: 612 MHPAANAFALMTLALPAMGFLV 677
           + PA N  +LMTL +P    L+
Sbjct: 142 VKPAINNISLMTLGVPCTALLI 163


>BC112124-1|AAI12125.1|  264|Homo sapiens N-acylsphingosine
           amidohydrolase (alkaline ceramidase) 3 protein.
          Length = 264

 Score =  109 bits (261), Expect = 1e-23
 Identities = 56/134 (41%), Positives = 82/134 (61%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           N+  S L+AEF NT SNI FF+F P+++ L   Y++  +  I V+WVL MI+GL S YFH
Sbjct: 18  NFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMIIGLFSMYFH 77

Query: 435 ATLSLVGQLLDELAILWVFMAAFAISCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLVM 614
            TLS +GQLLDE+AILW+  + ++I   +  F +F             + +V+ST    +
Sbjct: 78  MTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITTVVSTLLSFL 137

Query: 615 HPAANAFALMTLAL 656
            P  NA+AL ++AL
Sbjct: 138 RPTVNAYALNSIAL 151


>BC112122-1|AAI12123.1|  264|Homo sapiens N-acylsphingosine
           amidohydrolase 3 protein.
          Length = 264

 Score =  109 bits (261), Expect = 1e-23
 Identities = 56/134 (41%), Positives = 82/134 (61%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           N+  S L+AEF NT SNI FF+F P+++ L   Y++  +  I V+WVL MI+GL S YFH
Sbjct: 18  NFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMIIGLFSMYFH 77

Query: 435 ATLSLVGQLLDELAILWVFMAAFAISCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLVM 614
            TLS +GQLLDE+AILW+  + ++I   +  F +F             + +V+ST    +
Sbjct: 78  MTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITTVVSTLLSFL 137

Query: 615 HPAANAFALMTLAL 656
            P  NA+AL ++AL
Sbjct: 138 RPTVNAYALNSIAL 151


>AF347024-1|AAL83822.1|  264|Homo sapiens alkaline ceramidase
           protein.
          Length = 264

 Score =  109 bits (261), Expect = 1e-23
 Identities = 56/134 (41%), Positives = 82/134 (61%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           N+  S L+AEF NT SNI FF+F P+++ L   Y++  +  I V+WVL MI+GL S YFH
Sbjct: 18  NFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIYVVWVLFMIIGLFSMYFH 77

Query: 435 ATLSLVGQLLDELAILWVFMAAFAISCLKYIFRNFWEETGEYLALYSSVFSVMSTGFLVM 614
            TLS +GQLLDE+AILW+  + ++I   +  F +F             + +V+ST    +
Sbjct: 78  MTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQFIRLVFITTVVSTLLSFL 137

Query: 615 HPAANAFALMTLAL 656
            P  NA+AL ++AL
Sbjct: 138 RPTVNAYALNSIAL 151


>BC092487-1|AAH92487.1|  226|Homo sapiens ASAH3L protein protein.
          Length = 226

 Score = 97.9 bits (233), Expect = 3e-20
 Identities = 48/113 (42%), Positives = 72/113 (63%), Gaps = 1/113 (0%)
 Frame = +3

Query: 342 LFQEYSKFFNPAINVLWVLLMIVGLSSAYFHATLSLVGQLLDELAILWVFMAAFAI-SCL 518
           LF++Y+  FN  I ++W LL++VG+ S YFHATLS +GQ+LDELA+LWV M A A+    
Sbjct: 3   LFRQYATCFNSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPR 62

Query: 519 KYIFRNFWEETGEYLALYSSVFSVMSTGFLVMHPAANAFALMTLALPAMGFLV 677
           +Y+ + F  + G +  +  SV S ++T    + PA N  +LMTL +P    L+
Sbjct: 63  RYLPKIFRNDRGRFKVVV-SVLSAVTTCLAFVKPAINNISLMTLGVPCTALLI 114


>BC073853-1|AAH73853.1|  267|Homo sapiens phytoceramidase, alkaline
           protein.
          Length = 267

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NYS++  IAEF NTVSN++  +  P +    Q             ++ L +VG+ S  FH
Sbjct: 24  NYSVTWYIAEFWNTVSNLIMII--PPMFGAIQSVRDGLEKRYIASYLALTVVGMGSWCFH 81

Query: 435 ATLSLVGQLLDELAILW 485
            TL    QLLDEL +++
Sbjct: 82  MTLKYEMQLLDELPMIY 98


>AF327353-1|AAL56013.1|  267|Homo sapiens alkaline dihydroceramidase
           SB89 protein.
          Length = 267

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NYS++  IAEF NTVSN++  +  P +    Q             ++ L +VG+ S  FH
Sbjct: 24  NYSVTWYIAEFWNTVSNLIMII--PPMFGAIQSVRDGLEKRYIASYLALTVVGMGSWCFH 81

Query: 435 ATLSLVGQLLDELAILW 485
            TL    QLLDEL +++
Sbjct: 82  MTLKYEMQLLDELPMIY 98


>AF214454-1|AAK71923.1|  267|Homo sapiens alkaline phytoceramidase
           protein.
          Length = 267

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 28/77 (36%), Positives = 41/77 (53%)
 Frame = +3

Query: 255 NYSISPLIAEFVNTVSNILFFLFPPVLIHLFQEYSKFFNPAINVLWVLLMIVGLSSAYFH 434
           NYS++  IAEF NTVSN++  +  P +    Q             ++ L +VG+ S  FH
Sbjct: 24  NYSVTWYIAEFWNTVSNLIMII--PPMFGAIQSVRDGLEKRYIASYLALTVVGMGSWCFH 81

Query: 435 ATLSLVGQLLDELAILW 485
            TL    QLLDEL +++
Sbjct: 82  MTLKYEMQLLDELPMIY 98


>BC114631-1|AAI14632.1|  339|Homo sapiens chromosome 6 open reading
           frame 151 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 5.9
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 356 IFLEKMNQHWWEQKEQNIAHSVNEFCYQRRYGIIDSHQSTGELPRSRC 213
           + +E+++ HW  Q+EQ  A    E   +RR   +DS QS G    + C
Sbjct: 247 VHMEELSNHW--QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAEC 292


>BC114630-1|AAI14631.1|  339|Homo sapiens chromosome 6 open reading
           frame 151 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 5.9
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 356 IFLEKMNQHWWEQKEQNIAHSVNEFCYQRRYGIIDSHQSTGELPRSRC 213
           + +E+++ HW  Q+EQ  A    E   +RR   +DS QS G    + C
Sbjct: 247 VHMEELSNHW--QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAEC 292


>AY164485-1|AAO32798.1| 1732|Homo sapiens polycystic kidney disease
            1-like 3 protein.
          Length = 1732

 Score = 30.7 bits (66), Expect = 5.9
 Identities = 24/71 (33%), Positives = 37/71 (52%)
 Frame = +3

Query: 381  NVLWVLLMIVGLSSAYFHATLSLVGQLLDELAILWVFMAAFAISCLKYIFRNFWEETGEY 560
            +V W+LL    L+SA+F A  SL  +L  + A  W  M +  +S L+ IF +   +   +
Sbjct: 1155 SVCWLLLGFTSLASAFFTALYSL--ELSKDQATSW--MISIILSVLQNIFISQPVKVVFF 1210

Query: 561  LALYSSVFSVM 593
              LYS + S M
Sbjct: 1211 TFLYSLMMSRM 1221


>AL390026-2|CAI20238.1|  339|Homo sapiens chromosome 6 open reading
           frame 151 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 5.9
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 356 IFLEKMNQHWWEQKEQNIAHSVNEFCYQRRYGIIDSHQSTGELPRSRC 213
           + +E+++ HW  Q+EQ  A    E   +RR   +DS QS G    + C
Sbjct: 247 VHMEELSNHW--QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAEC 292


>AL031058-2|CAI21647.2|  339|Homo sapiens chromosome 6 open reading
           frame 151 protein.
          Length = 339

 Score = 30.7 bits (66), Expect = 5.9
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = -3

Query: 356 IFLEKMNQHWWEQKEQNIAHSVNEFCYQRRYGIIDSHQSTGELPRSRC 213
           + +E+++ HW  Q+EQ  A    E   +RR   +DS QS G    + C
Sbjct: 247 VHMEELSNHW--QEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAEC 292


>BX537565-1|CAD97783.1|  461|Homo sapiens hypothetical protein
           protein.
          Length = 461

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


>BC068556-1|AAH68556.1|  461|Homo sapiens solute carrier family 46,
           member 3 protein.
          Length = 461

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


>BC060850-1|AAH60850.1|  463|Homo sapiens SLC46A3 protein protein.
          Length = 463

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


>BC036662-1|AAH36662.1|  461|Homo sapiens solute carrier family 46,
           member 3 protein.
          Length = 461

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


>AL359454-3|CAM24029.1|  461|Homo sapiens novel protein protein.
          Length = 461

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


>AL359454-2|CAI17158.1|  463|Homo sapiens novel protein protein.
          Length = 463

 Score = 30.3 bits (65), Expect = 7.8
 Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 5/30 (16%)
 Frame = +3

Query: 486 VFMAAFAISCL-----KYIFRNFWEETGEY 560
           +F++AFA++       +Y++R  WEETG Y
Sbjct: 10  IFLSAFAMTLTGPLTTQYVYRRIWEETGNY 39


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,040,103
Number of Sequences: 237096
Number of extensions: 2563424
Number of successful extensions: 4685
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4585
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4679
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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