Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0222
(758 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 139 6e-32
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 134 2e-30
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 109 1e-22
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 106 5e-22
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 103 5e-21
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 103 5e-21
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 101 1e-20
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 101 3e-20
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 100 4e-20
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 99 1e-19
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 97 4e-19
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 94 3e-18
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 93 7e-18
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 93 7e-18
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 93 9e-18
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 92 1e-17
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 2e-17
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 91 2e-17
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 90 5e-17
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 89 8e-17
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 87 6e-16
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 86 1e-15
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 85 1e-15
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 5e-15
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 2e-14
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 3e-14
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 81 3e-14
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 81 3e-14
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 81 4e-14
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 77 5e-13
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 76 1e-12
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 75 1e-12
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 75 1e-12
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 75 3e-12
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 74 4e-12
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 73 6e-12
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 8e-12
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 1e-10
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 66 7e-10
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 64 4e-09
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 62 2e-08
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 60 6e-08
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 56 9e-07
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 45 0.002
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 44 0.005
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 43 0.007
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 40 0.088
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 38 0.20
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 36 0.82
UniRef50_A6G0M8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.4
UniRef50_A7H9V5 Cluster: NADH dehydrogenase; n=4; Cystobacterine... 33 5.8
UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Re... 33 5.8
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 139 bits (337), Expect = 6e-32
Identities = 91/198 (45%), Positives = 111/198 (56%), Gaps = 5/198 (2%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
+ALR+AGL V+DVS++T PEMLGGRVKTLHPAVHAGIL+ D DM R + +I V
Sbjct: 39 KALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRV 98
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR-----TTTGSPSSVTRPTTML 478
V CNLY FV+TV+ P VTV +AVE IDIGGVTLLRA + T P +T +
Sbjct: 99 VACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEM 158
Query: 479 *SKKSKRTNISDDFGHKGRX*P*RRSLHTFGL*PCHIGTTSASNYSXGASPN*P*DYGMX 658
S +SK T++ R + HT I YS G S P YGM
Sbjct: 159 QSSESKDTSL-----ETRRQLALKAFTHTAQYDEA-ISDYFRKQYSKGVSQM-PLRYGMN 211
Query: 659 PHQKPGPRYSRPETXLPI 712
PHQ P Y+ + LPI
Sbjct: 212 PHQTPAQLYTL-QPKLPI 228
Score = 50.0 bits (114), Expect = 6e-05
Identities = 23/35 (65%), Positives = 29/35 (82%)
Frame = +1
Query: 28 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTA 38
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/73 (41%), Positives = 40/73 (54%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAFTSYFRTMTLPYRDYFRX 606
KNH RVTVVC+P DY V E++ ++ + LALKAFT + DYFR
Sbjct: 137 KNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT-HTAQYDEAISDYFRK 195
Query: 607 QLLARGKPQLTLR 645
Q ++G Q+ LR
Sbjct: 196 Q-YSKGVSQMPLR 207
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 134 bits (325), Expect = 2e-30
Identities = 89/194 (45%), Positives = 110/194 (56%), Gaps = 1/194 (0%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
+ LR+AG V+DVS++T PEMLGGRVKTLHPAVH GIL+ S +D DM++ Y +I V
Sbjct: 33 KTLRDAGWAVRDVSELTGHPEMLGGRVKTLHPAVHGGILARKSPADTADMEKLGYSLIRV 92
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*SKKS 493
VVCNLY FV+TVS P VTV DAVE IDIGGVTLLRA + + R T +
Sbjct: 93 VVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA-------AAKNHARVTVVCDPADY 145
Query: 494 KRTNISDDFGHKGRX*P*RRSLHTFGL*PCHIGTTSASNYSXGASPN*P*DYGMXPHQKP 673
R + G R P R L T T++ + S A P+ YGM PHQ P
Sbjct: 146 PRV-AEEMEGSGSRDTPSRTRLST-----TRPYRTTSGDSSAVAFPSCLCVYGMNPHQAP 199
Query: 674 GPRYS-RPETXLPI 712
Y+ RP L +
Sbjct: 200 AQLYTLRPALPLRV 213
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/32 (71%), Positives = 26/32 (81%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
ALLSVSDKTGL+ AK L + GL L+ASGGTA
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTA 32
Score = 39.5 bits (88), Expect = 0.088
Identities = 16/23 (69%), Positives = 19/23 (82%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIK 495
KNH RVTVVCDPADY V +E++
Sbjct: 131 KNHARVTVVCDPADYPRVAEEME 153
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 109 bits (261), Expect = 1e-22
Identities = 49/96 (51%), Positives = 70/96 (72%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
+ L+ AG+ V++VS+ T +PE+LGGRVKTLHP +H GIL+ + D+ ++K + I +
Sbjct: 36 KTLQEAGIKVKEVSEYTSSPEILGGRVKTLHPMIHGGILARDTKEDRAELKALGFSGIDI 95
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V+ NLY F +T+S PD T +D +ENIDIGGV LLRA
Sbjct: 96 VIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 43.2 bits (97), Expect = 0.007
Identities = 21/43 (48%), Positives = 29/43 (67%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAF 555
KN+ RVTV+CDPADYD V EI++ + + + LA+KAF
Sbjct: 134 KNYSRVTVICDPADYDEVSSEIEKTGEIS--LSLRKRLAIKAF 174
Score = 38.3 bits (85), Expect = 0.20
Identities = 21/38 (55%), Positives = 21/38 (55%)
Frame = +1
Query: 34 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
L L SVSDKTGL A L G IASGGTA E
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQE 40
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 106 bits (255), Expect = 5e-22
Identities = 53/97 (54%), Positives = 68/97 (70%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMIS 310
+ L+ AG+ V VSD T APE+LGGRVKTLHP +H GIL+ SDQ D++ +
Sbjct: 38 KTLKEAGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILARRDLPSDQADLEANDIRPLD 97
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F QT++KP VTVA+AVE IDIGG ++RA
Sbjct: 98 LVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134
Score = 39.9 bits (89), Expect = 0.067
Identities = 22/40 (55%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASE 147
+LALLSVSDK+G++ LA+ L +E LI+SGGTA E
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKE 42
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 103 bits (247), Expect = 5e-21
Identities = 52/97 (53%), Positives = 69/97 (71%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSD-QEDMKRQKYEMIS 310
++L + GL VQ VSD+T PEML GRVKTLHP +H G+L+ + Q D+ + + IS
Sbjct: 35 KSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLARPELAHHQADLNKYNIKPIS 94
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY FV+TVSK T+ +A+ENIDIGG TL+RA
Sbjct: 95 IVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
Score = 36.3 bits (80), Expect = 0.82
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
ALLSV +K+G++ +K LS G LI++GGTA
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTA 34
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 103 bits (247), Expect = 5e-21
Identities = 51/97 (52%), Positives = 68/97 (70%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
R L A + V+ VSD+T PE++ GRVKTLHPAVH GIL+ + ++ Q ++I
Sbjct: 36 RILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLID 95
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F QTV+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 96 MVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
Score = 37.9 bits (84), Expect = 0.27
Identities = 16/33 (48%), Positives = 26/33 (78%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K A+LSVS+KTG++ AK+L++ +L ++GGT
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGT 34
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 101 bits (243), Expect = 1e-20
Identities = 52/96 (54%), Positives = 65/96 (67%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
R L +AGL V +VSD T PEM+ GRVKTLHP VH GIL D M + + I +
Sbjct: 42 RLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILG-RRGQDDGIMAQHGIQPIDI 100
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
VV NLY F QTV++PD ++ DAVENIDIGG T++R+
Sbjct: 101 VVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
Score = 43.2 bits (97), Expect = 0.007
Identities = 18/32 (56%), Positives = 28/32 (87%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
ALLSVSDK G++ A++LS+ G++L+++GGTA
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTA 41
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 101 bits (241), Expect = 3e-20
Identities = 57/113 (50%), Positives = 71/113 (62%), Gaps = 4/113 (3%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQED-MKRQKYEMISVV 316
LR+AGL V DVS+ T PEML GRVKTLHP VH GIL+ ++ D + I +V
Sbjct: 40 LRDAGLPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILARRDLAEHMDTIAAHDISRIDLV 99
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRAXPR---TTTGSPSSVTRP 466
V NLY F TV++PD T+ DA+ENIDIGG T++RA + T G VT P
Sbjct: 100 VVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152
Score = 39.9 bits (89), Expect = 0.067
Identities = 17/32 (53%), Positives = 26/32 (81%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
AL+SVSDK G+L A+ L+ G++L+++GGTA
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTA 37
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 100 bits (239), Expect = 4e-20
Identities = 47/96 (48%), Positives = 67/96 (69%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
RAL G+ V VS+ T APE+L GRVKTLHP +H GIL+ +++ Q +++ I +
Sbjct: 49 RALSELGVAVVKVSEFTGAPEILDGRVKTLHPKIHGGILALPTEAHQRELELHDIAPIDL 108
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V+ NLY F +T++KP + ADA+ENIDIGG T++RA
Sbjct: 109 VIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRA 144
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 98.7 bits (235), Expect = 1e-19
Identities = 52/96 (54%), Positives = 64/96 (66%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
+ L L V +VSD T PEM+ GRVKTLHP VH GIL +D M++ E I +
Sbjct: 41 KLLAQNALPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILG-RRGTDDAIMQQHGIEGIDM 99
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
VV NLY F TV+KPD T+ADAVENIDIGG T++R+
Sbjct: 100 VVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
Score = 40.7 bits (91), Expect = 0.038
Identities = 18/32 (56%), Positives = 27/32 (84%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
ALLSVSDKTG++ A+ L + G++L+++GGTA
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTA 40
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 97.1 bits (231), Expect = 4e-19
Identities = 46/97 (47%), Positives = 67/97 (69%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
+ LR+A + V DVS++T PEM+GGRVKTLHP +H G+L +Q E+ ++ +I
Sbjct: 37 KILRDADIEVTDVSEVTGYPEMMGGRVKTLHPRIHGGLLCLRESKEQMEEAAKEDISLID 96
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
++ NLY F TVS+ +V + +A+ENIDIGG TLLR+
Sbjct: 97 LIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
Score = 43.2 bits (97), Expect = 0.007
Identities = 19/34 (55%), Positives = 27/34 (79%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
K ALLSVSDKTG++ A+ L G+++I++GGTA
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTA 36
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 94.3 bits (224), Expect = 3e-18
Identities = 47/94 (50%), Positives = 62/94 (65%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
+R AGL VQDV+D+T PEM+ GRVKTLHP VH G+L + D M + I +++
Sbjct: 45 IREAGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLG-RAGIDDAVMAKHGIAPIDLLI 103
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
NLY F Q +K D T+ADAV+ IDIGG +LR+
Sbjct: 104 LNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/33 (60%), Positives = 28/33 (84%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT 135
ALLSVSDKTGL+ LA++L ++L+++GGTAT
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTAT 43
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 93.1 bits (221), Expect = 7e-18
Identities = 45/97 (46%), Positives = 65/97 (67%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*L-SDSDQEDMKRQKYEMIS 310
+ LR AG+ V+DVSD+T PEM+ GRVKTLHP +H G+L S S + M+ E I
Sbjct: 47 KTLREAGIEVRDVSDVTGFPEMMDGRVKTLHPKIHGGLLGVRDSPSHESSMREHGIEPID 106
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV +LY F +T+ V++A+A+E IDIGG ++R+
Sbjct: 107 MVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
Score = 37.1 bits (82), Expect = 0.47
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
AL+SVSDKTG++ A L ++++++GGTA
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTA 46
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 93.1 bits (221), Expect = 7e-18
Identities = 44/97 (45%), Positives = 68/97 (70%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSD-SDQEDMKRQKYEMIS 310
+ L++ G+ + D T PE+L GRVKTLHP VH G+L +S+ + ++ M+ K I
Sbjct: 39 KLLKDNGIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKID 98
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F++TVSKP+V + +A+ENIDIGG +++R+
Sbjct: 99 LVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
Score = 41.5 bits (93), Expect = 0.022
Identities = 18/33 (54%), Positives = 28/33 (84%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SVSDK+GL+ AK L++ G+++I++GGT
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGT 37
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 92.7 bits (220), Expect = 9e-18
Identities = 45/97 (46%), Positives = 62/97 (63%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
R++ AG+ V V ++T PEML GRVKTLHP +H G+L S+ + M+ I
Sbjct: 37 RSIAEAGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSID 96
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+V NLY F +TV KPDV+ D +ENIDIGG ++LR+
Sbjct: 97 LVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
Score = 42.7 bits (96), Expect = 0.009
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
K AL+SVSDKT ++ AK L E G +++++GGT +E
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAE 41
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/97 (50%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMIS 310
+AL AG+ V VS+ T APE+LGGRVKTLHP +H GIL+ L D+ D++ I
Sbjct: 43 KALSEAGIPVTPVSEHTGAPEILGGRVKTLHPRIHGGILARLERREDRADLEALGIPPIQ 102
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV N Y F QTV++ V++ +A E IDIGG TL RA
Sbjct: 103 LVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARA 139
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/39 (66%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +1
Query: 34 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASE 147
LALLSVSDKTGL+ LA++L E G QL++SGGTA SE
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSE 47
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 91.9 bits (218), Expect = 2e-17
Identities = 43/94 (45%), Positives = 64/94 (68%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L ++G+ + +SDIT ++L GRVKTLHPAV +GILS + + D+KR Y +V+
Sbjct: 34 LSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRDEQSEADLKRYNYFDFDIVI 93
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
CNLY+F + K ++ D +ENIDIGG++L+RA
Sbjct: 94 CNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 91.5 bits (217), Expect = 2e-17
Identities = 50/97 (51%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDS-DQEDMKRQKYEMIS 310
+AL AG+ V VS T APE+LGGRVKTLHP +H GIL+ L S D+ D++ I
Sbjct: 51 KALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLECSEDRADLEALGIPPIQ 110
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV N Y F QTV++ V++ +A E IDIGG TL RA
Sbjct: 111 LVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/39 (69%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +1
Query: 34 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASE 147
LALLSVSDKTGL+ LA+SL E G QL++SGGTA SE
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSE 55
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 90.2 bits (214), Expect = 5e-17
Identities = 46/96 (47%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
Frame = +2
Query: 137 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMISV 313
AL AG+T + D+T PEM+ GRVKTLHP +H G+L+ DS + + +I +
Sbjct: 38 ALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDL 97
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
VV NLY F +T+ +PDVT AVENIDIGG ++LR+
Sbjct: 98 VVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
Score = 41.1 bits (92), Expect = 0.029
Identities = 31/83 (37%), Positives = 38/83 (45%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAFTSYFRTMTLPYRDYFRX 606
KNH VTVV DPADY V+ EI E +A Q LA K F + DYF
Sbjct: 136 KNHASVTVVVDPADYPTVLGEIAEQGETS--YATRQRLAAKVF-RHTAAYDALIADYFTK 192
Query: 607 QLLARGKPQLTLRLRYEXTSEAR 675
Q + KP+ L + Y+ R
Sbjct: 193 Q-VGEDKPE-KLTITYDLNQPMR 213
Score = 38.3 bits (85), Expect = 0.20
Identities = 16/33 (48%), Positives = 26/33 (78%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SVSDK G++ A+ L++ G ++I++GGT
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGT 35
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 89.4 bits (212), Expect = 8e-17
Identities = 47/97 (48%), Positives = 63/97 (64%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*L-SDSDQEDMKRQKYEMIS 310
+A+ +AGL V+DVSD+T PEM+ GRVKTLHP VH G+L+ +D E MK I
Sbjct: 43 KAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLAIRGNDEHAEAMKTHGIAPID 102
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
++V NLY F TV + +D +ENIDIGG ++RA
Sbjct: 103 LLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
Score = 46.0 bits (104), Expect = 0.001
Identities = 21/37 (56%), Positives = 30/37 (81%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
ALLSVSDKTGL+ A+SL+ G++LI++GGTA ++
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIAD 47
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 86.6 bits (205), Expect = 6e-16
Identities = 46/97 (47%), Positives = 63/97 (64%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSD-QEDMKRQKYEMIS 310
RAL AGL V++VS++TR PEM+ GRVKTLHPAVH G+L+ + + Q + I
Sbjct: 92 RALTEAGLAVREVSELTRFPEMMDGRVKTLHPAVHGGLLAVRDNPEHQAALAAHGIGAID 151
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
++V NLY F +T+ K D VENID+GG ++RA
Sbjct: 152 LLVVNLYPFEETL-KAGKAYDDCVENIDVGGPAMIRA 187
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/37 (54%), Positives = 28/37 (75%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
ALLSVSDKTGL A +LS+ G++L+++GGT +E
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTE 96
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 85.8 bits (203), Expect = 1e-15
Identities = 49/97 (50%), Positives = 62/97 (63%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSD-SDQEDMKRQKYEMIS 310
+ L +AG+ V+ VSD+T PE+LGGRVKTLHP + GIL+ L D S +D++ E I
Sbjct: 38 KLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKSHVKDLRDNFIEPID 97
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F V K +ENIDIGGV LLRA
Sbjct: 98 LVVVNLYPF-DEVQKKTRDEDVLIENIDIGGVALLRA 133
Score = 43.6 bits (98), Expect = 0.005
Identities = 20/36 (55%), Positives = 29/36 (80%)
Frame = +1
Query: 25 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
N K AL+SVSDK GL+ AK+L + G+++I++GGTA
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTA 37
Score = 39.9 bits (89), Expect = 0.067
Identities = 16/22 (72%), Positives = 17/22 (77%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEI 492
KNH V VVCDPADYD V+K I
Sbjct: 136 KNHRNVVVVCDPADYDKVIKSI 157
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 85.4 bits (202), Expect = 1e-15
Identities = 45/97 (46%), Positives = 61/97 (62%), Gaps = 2/97 (2%)
Frame = +2
Query: 137 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*L-SDSDQEDMKRQKYEMISV 313
AL AG++V V ++TR PEML GRVKTLHP+VH GIL+ + E +++ + V
Sbjct: 124 ALEGAGVSVTKVEELTRFPEMLDGRVKTLHPSVHGGILARRDQEHHMEALEKHEIGTFDV 183
Query: 314 VVCNLYHFVQTVSKPD-VTVADAVENIDIGGVTLLRA 421
VV NLY F VS ++ D +ENIDIGG ++RA
Sbjct: 184 VVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
Score = 39.5 bits (88), Expect = 0.088
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = +1
Query: 4 AXQNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT 135
A ++ S K AL+S+SDKT L L L E G ++++GGT++
Sbjct: 80 APKSSTSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSS 123
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 85.4 bits (202), Expect = 1e-15
Identities = 41/97 (42%), Positives = 63/97 (64%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
+ L+ G+ V +S++T PE++ GR+KTLHP +H G+L+ + + + + I
Sbjct: 38 KLLQENGVDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPID 97
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F +T+SK DVT +A+ENIDIGG +LRA
Sbjct: 98 LVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 41.1 bits (92), Expect = 0.029
Identities = 18/33 (54%), Positives = 26/33 (78%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SVSDKT L+ K L+E G+++I++GGT
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGT 36
Score = 37.1 bits (82), Expect = 0.47
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKE 498
KNH VTV+ DPADY V+ +IKE
Sbjct: 137 KNHQDVTVIVDPADYSPVLNQIKE 160
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 85.4 bits (202), Expect = 1e-15
Identities = 47/95 (49%), Positives = 65/95 (68%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL-S*LSDSDQEDMKRQKYEMISVV 316
LR G++V++VS+IT PE+L GRVKTLHP VH GIL + D+E++++ + I VV
Sbjct: 37 LREKGISVKEVSEITGFPEILEGRVKTLHPVVHGGILFRDWVEKDKEEIEKHGIKPIDVV 96
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V NLY F + + K +T D +E IDIGG TL+RA
Sbjct: 97 VVNLYPFEEKL-KEGLTDKDLMEFIDIGGPTLIRA 130
Score = 35.5 bits (78), Expect = 1.4
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASER 150
A++SV K G+ LAK+L E G +++++GGTA E+
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREK 40
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 84.6 bits (200), Expect = 2e-15
Identities = 41/87 (47%), Positives = 62/87 (71%), Gaps = 1/87 (1%)
Frame = +2
Query: 164 QDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSD-SDQEDMKRQKYEMISVVVCNLYHFV 340
Q+VS+ T +PE+LGGRVKTLHP +HAGILS +D S +++K +Y+ I +V+ N Y F
Sbjct: 56 QEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKSHTKELKANQYDEIDLVIVNFYPFE 115
Query: 341 QTVSKPDVTVADAVENIDIGGVTLLRA 421
+T+ + + +ENID+GG T++RA
Sbjct: 116 KTLDQ-TTNHSKIIENIDVGGPTMVRA 141
Score = 35.1 bits (77), Expect = 1.9
Identities = 18/33 (54%), Positives = 25/33 (75%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SVSDK L SL + L++ ++LI+SGGT
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGT 44
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 83.4 bits (197), Expect = 5e-15
Identities = 43/96 (44%), Positives = 62/96 (64%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
+ALR AG+ +DVS+ T+ PEM+ GRVKTLHP VH G+L D + MK E I +
Sbjct: 36 KALREAGIPAKDVSEYTQFPEMMDGRVKTLHPKVHGGLLG-RRGIDDDVMKAHFIEPIDI 94
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+ NLY F + +SK ++ + + +E IDIGG ++RA
Sbjct: 95 LCVNLYPF-EEMSKKNLPLEELIEFIDIGGPAMIRA 129
Score = 40.3 bits (90), Expect = 0.050
Identities = 20/38 (52%), Positives = 27/38 (71%)
Frame = +1
Query: 34 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
LALLSV DKTG+L LA++L + +++SGGTA E
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALRE 40
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 81.8 bits (193), Expect = 2e-14
Identities = 44/92 (47%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Frame = +2
Query: 149 AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMISVVVCN 325
AG+ VQ+V ++T +PEML GRVKTLHP VH GIL+ + E + + E +VV N
Sbjct: 51 AGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILADRRVPAHMETLAGMEIEAFDLVVVN 110
Query: 326 LYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
LY FV+TV K D VE IDIGG ++R+
Sbjct: 111 LYPFVETV-KSGAAQDDVVEQIDIGGPAMVRS 141
Score = 40.3 bits (90), Expect = 0.050
Identities = 18/32 (56%), Positives = 25/32 (78%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
AL+SV DKTGL LAK L E G++++++G TA
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTA 45
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 81.0 bits (191), Expect = 3e-14
Identities = 43/94 (45%), Positives = 61/94 (64%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L+ L V DV T PE++ GRVKTLHP +HAG+L+ D++ + + + I ++V
Sbjct: 48 LKQHQLPVIDVFTYTGFPEIMDGRVKTLHPKIHAGLLA-RRGIDEKTLDQHAIKPIDLLV 106
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
NLY FVQTVS + ++ AVE IDIGG ++LRA
Sbjct: 107 VNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRA 140
Score = 40.3 bits (90), Expect = 0.050
Identities = 17/34 (50%), Positives = 24/34 (70%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
K AL+S +DK GL+ L CG+++IA+GGTA
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTA 45
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 81.0 bits (191), Expect = 3e-14
Identities = 44/96 (45%), Positives = 59/96 (61%), Gaps = 2/96 (2%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L AG+ V+ VSD+T PEML GRVKTLHPA+H GIL+ + Q I +V
Sbjct: 39 LSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARREAGHLGQLAAQDIGTIDLVC 98
Query: 320 CNLYHFVQTVSK--PDVTVADAVENIDIGGVTLLRA 421
NLY F +TV++ PD + +ENIDIGG ++R+
Sbjct: 99 VNLYPFRETVARGAPD---PEVIENIDIGGPAMIRS 131
Score = 38.7 bits (86), Expect = 0.15
Identities = 17/33 (51%), Positives = 25/33 (75%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SVSDKTG++ A L + G +L+++GGT
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGT 35
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 81.0 bits (191), Expect = 3e-14
Identities = 43/95 (45%), Positives = 63/95 (66%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSD-QEDMKRQKYEMISVV 316
L+ + V+++S+IT PEML GRVKTLHP VHAGIL+ + + + ++ ++ I V
Sbjct: 39 LKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYV 98
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V NLY F + V + D++ + VE IDIGG T+LRA
Sbjct: 99 VVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
Score = 37.5 bits (83), Expect = 0.36
Identities = 18/33 (54%), Positives = 25/33 (75%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
K AL+SV DK G+L LAK L + +++I+SGGT
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGT 35
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 80.6 bits (190), Expect = 4e-14
Identities = 46/95 (48%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMISVV 316
L+NAG+ +VS++T E+LGGRVKTLHPA+H GIL + D E++K E I +V
Sbjct: 37 LKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFREDVEKDLEEIKENSIEPIDIV 96
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V NLY F + + K + VE IDIGG TL+RA
Sbjct: 97 VVNLYPFEKKM-KELKDIDALVEFIDIGGPTLVRA 130
Score = 41.1 bits (92), Expect = 0.029
Identities = 19/33 (57%), Positives = 25/33 (75%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT 135
AL+SV DKTG+L LAK L G ++++SGGT T
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYT 35
Score = 33.5 bits (73), Expect = 5.8
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAF--TSYFRTMTLPY 588
KNH RV+V+ D DY ++++K N ++ + LALKAF TSY+ + Y
Sbjct: 133 KNHKRVSVLTDIEDYGWFIEKLKMNAVSQQ---DRKYLALKAFWLTSYYDAVIASY 185
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 77.0 bits (181), Expect = 5e-13
Identities = 40/96 (41%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
+ L G+ V +VSD+T PE L GRVKTLHP +HAGIL+ +++ + + ++ +
Sbjct: 43 KKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEHAKQLEEFGIKPFD 102
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLR 418
+VV NLY F TV + AD +E IDIGG +++R
Sbjct: 103 LVVVNLYPFADTV-RSGANEADTIEKIDIGGPSMVR 137
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 75.8 bits (178), Expect = 1e-12
Identities = 44/107 (41%), Positives = 64/107 (59%), Gaps = 1/107 (0%)
Frame = +2
Query: 149 AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS-*LSDSDQEDMKRQKYEMISVVVCN 325
AG+ V V D+T PE+L GRVKTLHP +H+GIL+ + +E + + + +VVCN
Sbjct: 56 AGVAVTPVDDVTGFPEVLEGRVKTLHPFIHSGILADQRKAAHREQIAQLGIQAFDLVVCN 115
Query: 326 LYHFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTTGSPSSVTRP 466
LY F TV+ + + VE IDIGG +++RA + S + VT P
Sbjct: 116 LYPFQDTVAS-GASFDECVEQIDIGGPSMVRAAAKNHP-SVAVVTSP 160
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 75.8 bits (178), Expect = 1e-12
Identities = 41/96 (42%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEM--ISV 313
+ + G + V D+T P +LGGRVKTLHP + GIL D +Q+ + +KYE+ I +
Sbjct: 44 IESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILC-RRDLEQDIQQIEKYEIPEIDL 102
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V+ +LY F TV+ + AD +E IDIGG++L+RA
Sbjct: 103 VIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRA 137
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 75.4 bits (177), Expect = 1e-12
Identities = 38/101 (37%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS-*LSDSDQEDMKRQKYEMISVV 316
+R + V+DVS++T E+L GRVKTLHP +HA IL+ S + +++ + +V
Sbjct: 44 IRGVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQLQQLGVDAFDLV 103
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRAXPRTTT 439
V NLY F + + +D +E IDIGG L+RA + T
Sbjct: 104 VVNLYPFFEISKNSEAEFSDVIEQIDIGGSALIRAAAKNHT 144
Score = 36.7 bits (81), Expect = 0.62
Identities = 16/34 (47%), Positives = 27/34 (79%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
K AL+SVSDK+GL LA++L+ ++++++G TA
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTA 41
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 75.4 bits (177), Expect = 1e-12
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
+ L+ G+ V +VSD T++PE+ GRVKTLHP +H GIL SD + + K + I
Sbjct: 35 KLLKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENHIKQAKENEILGID 94
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+V NLY F +T D + +ENIDIGG ++R+
Sbjct: 95 LVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRS 130
Score = 37.1 bits (82), Expect = 0.47
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
ALLSVSDK G++ K L G +++++GGT
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGT 33
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 74.5 bits (175), Expect = 3e-12
Identities = 36/94 (38%), Positives = 56/94 (59%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L G+ VS+ PE++ GRVKTLHP +H GILS ++ + + K + I +V+
Sbjct: 45 LLEKGIFSTSVSEYINHPEIINGRVKTLHPKIHGGILS--NNKNINENKNLNIKKIDMVI 102
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
N Y F + V K ++ + + ++NIDIGGV L R+
Sbjct: 103 TNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/33 (54%), Positives = 26/33 (78%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGT 129
+ AL+SVSDKTG+ SLAK+L + ++LI + GT
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGT 41
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 73.7 bits (173), Expect = 4e-12
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQ-EDMKRQKYEMIS 310
R L AGL V VS +T PE++GGRVKTLHP +H GIL+ + + +K
Sbjct: 94 RTLTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILADKDNPEHLATLKELGIRTFD 153
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
++ NLY+F ++ + + AVE +DIGG +LRA
Sbjct: 154 LICVNLYNFADAAAR-GLDLRGAVEEVDIGGPCMLRA 189
Score = 38.3 bits (85), Expect = 0.20
Identities = 17/37 (45%), Positives = 28/37 (75%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
ALLSV+DK+GL+ A L++ G++L+++GGT +E
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTE 98
Score = 33.9 bits (74), Expect = 4.4
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAF--TSYFRTMTLPY 588
KN + V+ DPADY A ++E+++N +R A Q +A+K F TS + M Y
Sbjct: 192 KNFHSMLVLPDPADYQAAMQEMRDN-DMRVGLAMRQAMAVKTFRATSAYDGMIADY 246
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 73.3 bits (172), Expect = 6e-12
Identities = 42/85 (49%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +2
Query: 170 VSDITRAPEMLGGRVKTLHPAVHAGILS*L-SDSDQEDMKRQKYEMISVVVCNLYHFVQT 346
VSD T PE GG VKTL ++ G+L+ ++S DMKR I +VV NLY F QT
Sbjct: 69 VSDYTGQPETQGGLVKTLDFKIYLGLLTETYNESHARDMKRTGAVAIDMVVVNLYPFSQT 128
Query: 347 VSKPDVTVADAVENIDIGGVTLLRA 421
V++PDVT A NIDIGG ++RA
Sbjct: 129 VARPDVTPEQARGNIDIGGPCMVRA 153
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 72.9 bits (171), Expect = 8e-12
Identities = 38/94 (40%), Positives = 57/94 (60%), Gaps = 1/94 (1%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LS-DSDQEDMKRQKYEMISVV 316
+ + G + V D+TR P MLGGRVKTLHP + GIL+ +SD ++ +I +V
Sbjct: 45 ITSLGYACRAVDDLTRYPSMLGGRVKTLHPMIFGGILARRGHESDVREVGEYGLPLIDLV 104
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLR 418
+ +LY F TV+ + D +E IDIGG++L+R
Sbjct: 105 IVDLYPFEATVAS-GASEEDIIEKIDIGGISLIR 137
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 69.3 bits (162), Expect = 1e-10
Identities = 38/95 (40%), Positives = 54/95 (56%)
Frame = +2
Query: 137 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVV 316
AL AG+ +VS T PEM+ GRVKTLHP VH G+L D M + I ++
Sbjct: 67 ALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLG-RRQIDDAIMAKYGINRIGLL 125
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V NLY F + +S+ + + +E ID+GG ++RA
Sbjct: 126 VVNLYPF-ERMSRESLPLEKLIEYIDVGGPAMIRA 159
Score = 38.7 bits (86), Expect = 0.15
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 31 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT 135
K ALLSV DKTG++ LA++L + +++SGGT T
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGT 66
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 66.5 bits (155), Expect = 7e-10
Identities = 37/94 (39%), Positives = 53/94 (56%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L NAGLTV +SD T PE++ G+VKTLH + AGILS + D+ + + + I +V+
Sbjct: 44 LTNAGLTVNKISDYTNFPEIMNGQVKTLHHKICAGILS-RKNLDESIIHKYGIQPIDMVI 102
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
N Y F + +E IDIGG ++RA
Sbjct: 103 VNFYPFHLILQNKQHDSEKILEYIDIGGPNMVRA 136
Score = 37.1 bits (82), Expect = 0.47
Identities = 17/32 (53%), Positives = 25/32 (78%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTA 132
AL+SV DK+ LL +KSLS G++L+++ GTA
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTA 41
Score = 34.3 bits (75), Expect = 3.3
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Frame = +1
Query: 427 KNHDRVTVVCDPADYDAVVKEIKENKHLRRLWAQGQXLALKAFTSYFRTMTLPYRDYFRX 606
KN+ ++ D DYD ++ EI H LA KAF Y + DYF+
Sbjct: 139 KNYKNTVIIVDNNDYDNILNEI-NTLHGSISLNTRLNLAAKAF-KYIKQYDTMISDYFQH 196
Query: 607 QL-LARGKPQLTLRLRYE 657
QL L KP T++ R +
Sbjct: 197 QLKLQPNKPHHTIQKRIQ 214
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 64.1 bits (149), Expect = 4e-09
Identities = 29/94 (30%), Positives = 57/94 (60%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISVVV 319
L+ + D+++ T PE++ GR+KTLH ++A IL+ D++ +++ ++ +VV
Sbjct: 44 LKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILA-QPKHDKKTIEKYNIILMDIVV 102
Query: 320 CNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
N Y F + + ++ + D +E+IDIGG ++RA
Sbjct: 103 INFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRA 136
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/96 (37%), Positives = 53/96 (55%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEMISV 313
R LR+ G+TV VSD+ P +LGGRVKTL ++ GIL+ +D+ +++R + +
Sbjct: 35 RLLRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILARDEPADRAEVERHGLTRVHL 94
Query: 314 VVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V CN Y +P E ID+GG +LRA
Sbjct: 95 VCCNYYRLPD--PQPAQPFERFRELIDVGGPAMLRA 128
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 60.1 bits (139), Expect = 6e-08
Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 1/95 (1%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSD-SDQEDMKRQKYEMISVV 316
L+ G+ ++D PE+LGGRVK++ P + GIL+ +D +EDM + I +V
Sbjct: 40 LQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSNDKKHEEDMINYNIKRIDMV 99
Query: 317 VCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
V N F + ++K +ENIDIGG +LLRA
Sbjct: 100 VGNFPTF-EEIAKKTKNEETLLENIDIGGYSLLRA 133
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 56.0 bits (129), Expect = 9e-07
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +2
Query: 134 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSD-SDQEDMKRQKYEMIS 310
+AL AGL V V ++ E GR+KT+ + + +L D +D E I
Sbjct: 39 KALTEAGLKVTAVETLSGKGEAFNGRMKTISFEIASSLLFRRQDENDVRQAAELGIEPID 98
Query: 311 VVVCNLYHFVQTVSKPDVTVADAVENIDIGGVTLLRA 421
+VV NLY F T+ K + +ENIDIGG TLLRA
Sbjct: 99 LVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRA 134
Score = 49.6 bits (113), Expect = 8e-05
Identities = 25/37 (67%), Positives = 30/37 (81%)
Frame = +1
Query: 37 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE 147
ALLSVSDKTGLL LAK+L+ ++LIASGGTA +E
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTE 43
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +2
Query: 137 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDS-DQEDMKRQKYEMISV 313
AL NA ++ V +T P++L G VKTLHP + GIL E + V
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPRRDQKHHMEALNEHGIGTFDV 116
Query: 314 VVCNLYHFVQTVSKPDVTV 370
VV NLY F +P +T+
Sbjct: 117 VVVNLYPFYD--KQPKLTI 133
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 197 MLGGRVKTLHPAVHAGILS*LSDS-DQEDMKRQKYEMISVVVCNLYHFVQTVSKPDVTVA 373
ML G VKTLHP +H GIL+ E + VVV NLY F VS +
Sbjct: 1 MLDGHVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPFYDKVSLGGIEFE 60
Query: 374 DAVE 385
D +E
Sbjct: 61 DEIE 64
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 43.2 bits (97), Expect = 0.007
Identities = 20/37 (54%), Positives = 25/37 (67%)
Frame = +2
Query: 140 LRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 250
L++ G+ DVS IT +LGG VKTLHP + AGIL
Sbjct: 38 LKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGIL 74
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 39.5 bits (88), Expect = 0.088
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +2
Query: 137 ALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 250
AL NA ++ V +T P++L G VKTLHP + GIL
Sbjct: 57 ALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGIL 94
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 38.3 bits (85), Expect = 0.20
Identities = 21/34 (61%), Positives = 22/34 (64%)
Frame = -2
Query: 418 AQEGHAADVDVLDRVRHGHVRLRYRLDEMVXVTD 317
AQ AADVDVLDRV V LR RLDE + V D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 36.3 bits (80), Expect = 0.82
Identities = 18/36 (50%), Positives = 21/36 (58%)
Frame = -2
Query: 418 AQEGHAADVDVLDRVRHGHVRLRYRLDEMVXVTDHH 311
A+ G AAD+DVLD + HG V R E V V HH
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHH 447
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 36.3 bits (80), Expect = 0.82
Identities = 29/93 (31%), Positives = 38/93 (40%)
Frame = -2
Query: 415 QEGHAADVDVLDRVRHGHVRLRYRLDEMVXVTDHHAYXXXXXXXXXXXXXVG*SA*DPSM 236
Q G AADVDVLDRV V L E V V H +A +M
Sbjct: 423 QHGRAADVDVLDRVGQAAVGLGGDRLERVQV-QHQQVDGTDAVLGHDRIIQARTAQQAAM 481
Query: 235 YRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKR 137
+ + P H R + DV H+L+ +A + R
Sbjct: 482 HHRVQGLDPAVHHFREAGDVGHVLHGQARIADR 514
>UniRef50_A6G0M8 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 1041
Score = 33.9 bits (74), Expect = 4.4
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +1
Query: 484 KEIKENKHLRRLWAQGQXLALKAFTSYFRTMTLPYRDYFRXQLLARGKPQLTLRLRYEXT 663
+E++E + R W Q LA + S F M+ YR+ + QLL + L+ +LR E
Sbjct: 684 EELRERQDEARCWVS-QILAEMSDASNFTDMSALYREQIKPQLLHQAVEPLSRQLRTELN 742
Query: 664 SEARXQV 684
+ R V
Sbjct: 743 IDVRENV 749
>UniRef50_A7H9V5 Cluster: NADH dehydrogenase; n=4;
Cystobacterineae|Rep: NADH dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 431
Score = 33.5 bits (73), Expect = 5.8
Identities = 18/59 (30%), Positives = 32/59 (54%)
Frame = +2
Query: 128 PPRALRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILS*LSDSDQEDMKRQKYEM 304
PPRAL AGL ++ D A +++ + HPA+H G+ + + D E ++ K ++
Sbjct: 24 PPRALGQAGLAAENELDAPLASKLMTVNLGPSHPAMH-GVTRAVVELDGEMIRSMKLDI 81
>UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
Similarity - Yarrowia lipolytica (Candida lipolytica)
Length = 337
Score = 33.5 bits (73), Expect = 5.8
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Frame = -1
Query: 335 NGXGYRPPRLSSRTSDVSCLPGQS-RIISLRSQHVPLDVKFSPDLRA 198
N GY ++ + CL G S I + PLDV F+PDLR+
Sbjct: 214 NDVGYISAAVNVANGQIFCLLGHSLAICDFAGNYTPLDVHFNPDLRS 260
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 671,840,257
Number of Sequences: 1657284
Number of extensions: 12450435
Number of successful extensions: 38116
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 36552
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38063
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62969581935
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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