Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0212
(549 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 112 6e-24
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 105 5e-22
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 98 1e-19
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 97 2e-19
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 96 4e-19
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 95 7e-19
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 95 1e-18
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 94 2e-18
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 93 4e-18
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 93 5e-18
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 92 7e-18
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 92 9e-18
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 91 1e-17
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 91 2e-17
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 90 3e-17
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 90 4e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 90 4e-17
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 90 4e-17
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 89 6e-17
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 87 3e-16
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 86 6e-16
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 85 8e-16
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 85 8e-16
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 85 1e-15
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 84 2e-15
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 84 2e-15
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 83 3e-15
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 82 7e-15
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 82 1e-14
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 2e-14
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 81 2e-14
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 80 3e-14
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 80 4e-14
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 75 8e-13
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 75 1e-12
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 72 1e-11
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 71 2e-11
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 68 1e-10
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 68 1e-10
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 67 3e-10
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 66 7e-10
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 65 9e-10
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 64 3e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 64 3e-09
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 60 3e-08
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 59 6e-08
UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n... 49 8e-05
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 44 0.002
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 38 0.20
UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to Carbamoyl-... 37 0.35
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 36 0.47
UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chai... 36 0.62
UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IM... 36 0.82
UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large subu... 36 0.82
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82
UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase pyrimidine... 35 1.1
UniRef50_Q53PF8 Cluster: Putative uncharacterized protein; n=1; ... 34 1.9
UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subun... 34 1.9
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 34 2.5
UniRef50_O17153 Cluster: Putative uncharacterized protein; n=1; ... 33 4.4
UniRef50_A5KA45 Cluster: Putative uncharacterized protein; n=2; ... 33 5.8
UniRef50_Q9HR54 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8
UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-relate... 32 7.6
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 32 7.6
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 32 7.6
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 112 bits (269), Expect = 6e-24
Identities = 54/75 (72%), Positives = 64/75 (85%)
Frame = +2
Query: 29 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGG 208
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA LR+AGL V+DVS++T PEMLGG
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGG 63
Query: 209 RVKTLHPAVHAGILA 253
RVKTLHPAVHAGILA
Sbjct: 64 RVKTLHPAVHAGILA 78
Score = 60.1 bits (139), Expect = 3e-08
Identities = 29/48 (60%), Positives = 33/48 (68%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
DM R + +I VV C L PFV V+ P VTV +AVE IDIGGVT LRA
Sbjct: 87 DMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRA 134
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 105 bits (253), Expect = 5e-22
Identities = 52/72 (72%), Positives = 59/72 (81%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTGL+ AK L + GL L+ASGGTA LR+AG V+DVS++T PEMLGGRVK
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVK 60
Query: 218 TLHPAVHAGILA 253
TLHPAVH GILA
Sbjct: 61 TLHPAVHGGILA 72
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/48 (66%), Positives = 35/48 (72%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
DM++ Y +I VVVC L PFV VS P VTV DAVE IDIGGVT LRA
Sbjct: 81 DMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQIDIGGVTLLRA 128
Score = 35.9 bits (79), Expect = 0.62
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +3
Query: 423 AKXHDRVTVVCDPADYDAVVKXIK 494
AK H RVTVVCDPADY V + ++
Sbjct: 130 AKNHARVTVVCDPADYPRVAEEME 153
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 97.9 bits (233), Expect = 1e-19
Identities = 46/72 (63%), Positives = 59/72 (81%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTGL+ A+SL+ G++LI++GGTA + +AGL V+DVSD+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVK 70
Query: 218 TLHPAVHAGILA 253
TLHP VH G+LA
Sbjct: 71 TLHPKVHGGLLA 82
Score = 32.7 bits (71), Expect = 5.8
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
MK I ++V L PF V + +D +ENIDIGG +RA
Sbjct: 93 MKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRA 138
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 97.5 bits (232), Expect = 2e-19
Identities = 45/71 (63%), Positives = 58/71 (81%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTGL+ LA++L ++L+++GGTAT +R AGL VQDV+D+T PEM+ GRVK
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVK 70
Query: 218 TLHPAVHAGIL 250
TLHP VH G+L
Sbjct: 71 TLHPMVHGGLL 81
Score = 39.5 bits (88), Expect = 0.050
Identities = 18/39 (46%), Positives = 25/39 (64%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I +++ L PF +K D T+ADAV+ IDIGG LR+
Sbjct: 99 IDLLILNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRS 137
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 96.3 bits (229), Expect = 4e-19
Identities = 45/72 (62%), Positives = 58/72 (80%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTGL A +LS+ G++L+++GGT L AGL V++VS++TR PEM+ GRVK
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 218 TLHPAVHAGILA 253
TLHPAVH G+LA
Sbjct: 120 TLHPAVHGGLLA 131
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 95.5 bits (227), Expect = 7e-19
Identities = 49/77 (63%), Positives = 59/77 (76%), Gaps = 1/77 (1%)
Frame = +2
Query: 35 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
LALLSVSDKTGL+ LA++L E G QL++SGGTA L AG+ V VS+ T APE+LGGR
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 212 VKTLHPAVHAGILAHYQ 262
VKTLHP +H GILA +
Sbjct: 69 VKTLHPRIHGGILARLE 85
Score = 34.3 bits (75), Expect = 1.9
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I +VV PF V++ V++ +A E IDIGG T RA
Sbjct: 101 IQLVVVNFYPFEQTVARAGVSLEEAFEQIDIGGPTLARA 139
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 95.1 bits (226), Expect = 1e-18
Identities = 50/77 (64%), Positives = 58/77 (75%), Gaps = 1/77 (1%)
Frame = +2
Query: 35 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
LALLSVSDKTGL+ LA+SL E G QL++SGGTA L AG+ V VS T APE+LGGR
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 212 VKTLHPAVHAGILAHYQ 262
VKTLHP +H GILA +
Sbjct: 77 VKTLHPRIHGGILARLE 93
Score = 33.9 bits (74), Expect = 2.5
Identities = 17/39 (43%), Positives = 23/39 (58%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I +VV PF V++ V++ +A E IDIGG T RA
Sbjct: 109 IQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARA 147
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 93.9 bits (223), Expect = 2e-18
Identities = 42/73 (57%), Positives = 57/73 (78%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K ALLSVSDKTG++ A+ L G+++I++GGTA LR+A + V DVS++T PEM+GGR
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGR 62
Query: 212 VKTLHPAVHAGIL 250
VKTLHP +H G+L
Sbjct: 63 VKTLHPRIHGGLL 75
Score = 41.5 bits (93), Expect = 0.012
Identities = 18/45 (40%), Positives = 29/45 (64%)
Frame = +1
Query: 286 RQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
++ +I ++ L PF VS+ +V + +A+ENIDIGG T LR+
Sbjct: 89 KEDISLIDLIAVNLYPFEITVSRENVELEEAIENIDIGGPTLLRS 133
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 93.1 bits (221), Expect = 4e-18
Identities = 45/72 (62%), Positives = 56/72 (77%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SVSDK G+L A+ L+ G++L+++GGTA LR+AGL V DVS+ T PEML GRVK
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVK 65
Query: 218 TLHPAVHAGILA 253
TLHP VH GILA
Sbjct: 66 TLHPKVHGGILA 77
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/39 (56%), Positives = 28/39 (71%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I +VV L PF V++PD T+ DA+ENIDIGG T +RA
Sbjct: 96 IDLVVVNLYPFQATVARPDCTLEDAIENIDIGGPTMVRA 134
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 92.7 bits (220), Expect = 5e-18
Identities = 44/76 (57%), Positives = 59/76 (77%)
Frame = +2
Query: 26 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLG 205
N K AL+SVSDK GL+ AK+L + G+++I++GGTA L +AG+ V+ VSD+T PE+LG
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 206 GRVKTLHPAVHAGILA 253
GRVKTLHP + GILA
Sbjct: 62 GRVKTLHPKIFGGILA 77
Score = 38.3 bits (85), Expect = 0.12
Identities = 16/23 (69%), Positives = 17/23 (73%)
Frame = +3
Query: 423 AKXHDRVTVVCDPADYDAVVKXI 491
AK H V VVCDPADYD V+K I
Sbjct: 135 AKNHRNVVVVCDPADYDKVIKSI 157
Score = 33.1 bits (72), Expect = 4.4
Identities = 21/48 (43%), Positives = 25/48 (52%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
D++ E I +VV L PF V K +ENIDIGGV LRA
Sbjct: 87 DLRDNFIEPIDLVVVNLYPF-DEVQKKTRDEDVLIENIDIGGVALLRA 133
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 92.3 bits (219), Expect = 7e-18
Identities = 47/75 (62%), Positives = 58/75 (77%), Gaps = 1/75 (1%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGG 208
+LALLSVSDK+G++ LA+ L +E LI+SGGTA L+ AG+ V VSD T APE+LGG
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 209 RVKTLHPAVHAGILA 253
RVKTLHP +H GILA
Sbjct: 63 RVKTLHPRIHGGILA 77
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/50 (46%), Positives = 31/50 (62%)
Frame = +1
Query: 271 QXDMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
Q D++ + +VV L PF ++KP VTVA+AVE IDIGG +RA
Sbjct: 85 QADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 91.9 bits (218), Expect = 9e-18
Identities = 43/71 (60%), Positives = 56/71 (78%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDK G++ A++LS+ G++L+++GGTA L +AGL V +VSD T PEM+ GRVK
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 218 TLHPAVHAGIL 250
TLHP VH GIL
Sbjct: 70 TLHPKVHGGIL 80
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/47 (46%), Positives = 31/47 (65%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
M + + I +VV L PF V++PD ++ DAVENIDIGG T +R+
Sbjct: 90 MAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRS 136
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 91.5 bits (217), Expect = 1e-17
Identities = 43/74 (58%), Positives = 55/74 (74%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDKTG++ A L + G +L+++GGT L AG+ V+ VSD+T PEML GR
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGR 62
Query: 212 VKTLHPAVHAGILA 253
VKTLHPA+H GILA
Sbjct: 63 VKTLHPAIHGGILA 76
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 90.6 bits (215), Expect = 2e-17
Identities = 42/72 (58%), Positives = 55/72 (76%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SV DKTGL LAK L E G++++++G TA + AG+ VQ+V ++T +PEML GRVK
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 218 TLHPAVHAGILA 253
TLHP VH GILA
Sbjct: 74 TLHPRVHGGILA 85
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 90.2 bits (214), Expect = 3e-17
Identities = 44/73 (60%), Positives = 52/73 (71%)
Frame = +2
Query: 35 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRV 214
L L SVSDKTGL A L G IASGGTA L+ AG+ V++VS+ T +PE+LGGRV
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 215 KTLHPAVHAGILA 253
KTLHP +H GILA
Sbjct: 63 KTLHPMIHGGILA 75
Score = 49.6 bits (113), Expect = 5e-05
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
++K + I +V+ L PF +S PD T +D +ENIDIGGV LRA
Sbjct: 84 ELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRA 131
Score = 37.1 bits (82), Expect = 0.27
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +3
Query: 423 AKXHDRVTVVCDPADYDAVVKXIKE 497
AK + RVTV+CDPADYD V I++
Sbjct: 133 AKNYSRVTVICDPADYDEVSSEIEK 157
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 89.8 bits (213), Expect = 4e-17
Identities = 42/71 (59%), Positives = 55/71 (77%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SV DKTG+L LAK L G ++++SGGT T L+NAG+ +VS++T E+LGGRVK
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVK 62
Query: 218 TLHPAVHAGIL 250
TLHPA+H GIL
Sbjct: 63 TLHPAIHGGIL 73
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 89.8 bits (213), Expect = 4e-17
Identities = 39/71 (54%), Positives = 54/71 (76%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SVSDKTG++ A L ++++++GGTA LR AG+ V+DVSD+T PEM+ GRVK
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVK 74
Query: 218 TLHPAVHAGIL 250
TLHP +H G+L
Sbjct: 75 TLHPKIHGGLL 85
Score = 37.9 bits (84), Expect = 0.15
Identities = 18/50 (36%), Positives = 28/50 (56%)
Frame = +1
Query: 271 QXDMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
+ M+ E I +VV L PF + V++A+A+E IDIGG +R+
Sbjct: 94 ESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIEQIDIGGPAMIRS 143
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 89.8 bits (213), Expect = 4e-17
Identities = 42/81 (51%), Positives = 57/81 (70%)
Frame = +2
Query: 11 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRA 190
++ S K AL+S+SDKT L L L E G ++++GGT++ L AG++V V ++TR
Sbjct: 82 KSSTSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRF 141
Query: 191 PEMLGGRVKTLHPAVHAGILA 253
PEML GRVKTLHP+VH GILA
Sbjct: 142 PEMLDGRVKTLHPSVHGGILA 162
Score = 35.1 bits (77), Expect = 1.1
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Frame = +1
Query: 289 QKYEM--ISVVVCXLXPFVXXVSKPD-VTVADAVENIDIGGVTXLRA 420
+K+E+ VVV L PF VS ++ D +ENIDIGG +RA
Sbjct: 174 EKHEIGTFDVVVVNLYPFYAKVSSSSGISFEDGIENIDIGGPAMIRA 220
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 89.0 bits (211), Expect = 6e-17
Identities = 42/72 (58%), Positives = 55/72 (76%)
Frame = +2
Query: 35 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRV 214
LALLSV DKTG+L LA++L + +++SGGTA LR AG+ +DVS+ T+ PEM+ GRV
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 215 KTLHPAVHAGIL 250
KTLHP VH G+L
Sbjct: 63 KTLHPKVHGGLL 74
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 87.0 bits (206), Expect = 3e-16
Identities = 42/72 (58%), Positives = 53/72 (73%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSV +K+G++ +K LS G LI++GGTA L + GL VQ VSD+T PEML GRVK
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 218 TLHPAVHAGILA 253
TLHP +H G+LA
Sbjct: 63 TLHPKIHGGLLA 74
Score = 52.8 bits (121), Expect = 5e-06
Identities = 25/50 (50%), Positives = 33/50 (66%)
Frame = +1
Query: 271 QXDMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
Q D+ + + IS+VV L PFV VSK T+ +A+ENIDIGG T +RA
Sbjct: 82 QADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRA 131
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 86.6 bits (205), Expect = 3e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SV DKTGL LA++L E G++++++G TA + AG+ V V D+T PE+L GR
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGR 76
Query: 212 VKTLHPAVHAGILA 253
VKTLHP +H+GILA
Sbjct: 77 VKTLHPFIHSGILA 90
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 85.8 bits (203), Expect = 6e-16
Identities = 40/74 (54%), Positives = 55/74 (74%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K A+LSVS+KTG++ AK+L++ +L ++GGT L A + V+ VSD+T PE++ GR
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 212 VKTLHPAVHAGILA 253
VKTLHPAVH GILA
Sbjct: 62 VKTLHPAVHGGILA 75
Score = 52.8 bits (121), Expect = 5e-06
Identities = 24/48 (50%), Positives = 33/48 (68%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
++ Q ++I +VV L PF V+ PDVT+ +A+ENIDIGG T LRA
Sbjct: 85 ELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRA 132
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 85.4 bits (202), Expect = 8e-16
Identities = 40/72 (55%), Positives = 54/72 (75%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSV+DK+GL+ A L++ G++L+++GGT L AGL V VS +T PE++GGRVK
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVK 121
Query: 218 TLHPAVHAGILA 253
TLHP +H GILA
Sbjct: 122 TLHPHIHGGILA 133
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 85.4 bits (202), Expect = 8e-16
Identities = 42/74 (56%), Positives = 55/74 (74%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SV DK G+L LAK L + +++I+SGGT L+ + V+++S+IT PEML GR
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 212 VKTLHPAVHAGILA 253
VKTLHP VHAGILA
Sbjct: 63 VKTLHPLVHAGILA 76
Score = 33.5 bits (73), Expect = 3.3
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
++ ++ I VV L PF V + D++ + VE IDIGG T LRA
Sbjct: 87 LEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEFIDIGGPTMLRA 132
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 84.6 bits (200), Expect = 1e-15
Identities = 37/73 (50%), Positives = 51/73 (69%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDKT ++ AK L E G +++++GGT + AG+ V V ++T PEML GR
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGR 62
Query: 212 VKTLHPAVHAGIL 250
VKTLHP +H G+L
Sbjct: 63 VKTLHPMIHGGLL 75
Score = 43.2 bits (97), Expect = 0.004
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
M+ I +V L PF V KPDV+ D +ENIDIGG + LR+
Sbjct: 87 MEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDIIENIDIGGPSMLRS 133
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 84.2 bits (199), Expect = 2e-15
Identities = 39/71 (54%), Positives = 54/71 (76%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
A++SV K G+ LAK+L E G +++++GGTA LR G++V++VS+IT PE+L GRVK
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVK 62
Query: 218 TLHPAVHAGIL 250
TLHP VH GIL
Sbjct: 63 TLHPVVHGGIL 73
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 83.8 bits (198), Expect = 2e-15
Identities = 42/76 (55%), Positives = 53/76 (69%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTG++ A+ L + G++L+++GGTA L L V +VSD T PEM+ GRVK
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 218 TLHPAVHAGILAHYQT 265
TLHP VH GIL T
Sbjct: 69 TLHPKVHGGILGRRGT 84
Score = 53.6 bits (123), Expect = 3e-06
Identities = 26/47 (55%), Positives = 33/47 (70%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
M++ E I +VV L PF V+KPD T+ADAVENIDIGG T +R+
Sbjct: 89 MQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDIGGPTMVRS 135
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 83.4 bits (197), Expect = 3e-15
Identities = 37/74 (50%), Positives = 53/74 (71%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDK G++ A+ L++ G ++I++GGT L AG+T + D+T PEM+ GR
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGR 62
Query: 212 VKTLHPAVHAGILA 253
VKTLHP +H G+LA
Sbjct: 63 VKTLHPKIHGGLLA 76
Score = 42.7 bits (96), Expect = 0.005
Identities = 21/40 (52%), Positives = 27/40 (67%)
Frame = +1
Query: 301 MISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
+I +VV L PF + +PDVT AVENIDIGG + LR+
Sbjct: 94 LIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRS 133
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 82.2 bits (194), Expect = 7e-15
Identities = 36/71 (50%), Positives = 50/71 (70%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDK G++ K L G +++++GGT L+ G+ V +VSD T++PE+ GRVK
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 218 TLHPAVHAGIL 250
TLHP +H GIL
Sbjct: 63 TLHPKIHGGIL 73
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 81.8 bits (193), Expect = 1e-14
Identities = 40/77 (51%), Positives = 52/77 (67%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K ALLSV DKTG++ LA++L + +++SGGT T L AG+ +VS T PEM+ GR
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGR 91
Query: 212 VKTLHPAVHAGILAHYQ 262
VKTLHP VH G+L Q
Sbjct: 92 VKTLHPKVHGGLLGRRQ 108
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 81.0 bits (191), Expect = 2e-14
Identities = 36/74 (48%), Positives = 54/74 (72%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDKT L+ K L+E G+++I++GGT L+ G+ V +S++T PE++ GR
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGR 63
Query: 212 VKTLHPAVHAGILA 253
+KTLHP +H G+LA
Sbjct: 64 LKTLHPNIHGGLLA 77
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/39 (56%), Positives = 26/39 (66%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I +VV L PF +SK DVT +A+ENIDIGG LRA
Sbjct: 96 IDLVVVNLYPFKETISKEDVTYEEAIENIDIGGPGMLRA 134
Score = 33.5 bits (73), Expect = 3.3
Identities = 14/25 (56%), Positives = 17/25 (68%)
Frame = +3
Query: 423 AKXHDRVTVVCDPADYDAVVKXIKE 497
+K H VTV+ DPADY V+ IKE
Sbjct: 136 SKNHQDVTVIVDPADYSPVLNQIKE 160
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 80.6 bits (190), Expect = 2e-14
Identities = 37/74 (50%), Positives = 55/74 (74%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDK+GL LA++L+ ++++++G TA +R + V+DVS++T E+L GR
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGR 67
Query: 212 VKTLHPAVHAGILA 253
VKTLHP +HA ILA
Sbjct: 68 VKTLHPKIHAPILA 81
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 80.6 bits (190), Expect = 2e-14
Identities = 39/72 (54%), Positives = 53/72 (73%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SV DK+ LL +KSLS G++L+++ GTA L NAGLTV +SD T PE++ G+VK
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 218 TLHPAVHAGILA 253
TLH + AGIL+
Sbjct: 70 TLHHKICAGILS 81
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 80.6 bits (190), Expect = 2e-14
Identities = 37/73 (50%), Positives = 53/73 (72%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDK+GL+ AK L++ G+++I++GGT L++ G+ + D T PE+L GR
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 212 VKTLHPAVHAGIL 250
VKTLHP VH G+L
Sbjct: 65 VKTLHPKVHGGLL 77
Score = 48.0 bits (109), Expect = 1e-04
Identities = 22/47 (46%), Positives = 32/47 (68%)
Frame = +1
Query: 280 MKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
M+ K I +VV L PF+ VSKP+V + +A+ENIDIGG + +R+
Sbjct: 89 MEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 80.2 bits (189), Expect = 3e-14
Identities = 38/74 (51%), Positives = 50/74 (67%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+S +DK GL+ L CG+++IA+GGTA L+ L V DV T PE++ GR
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 212 VKTLHPAVHAGILA 253
VKTLHP +HAG+LA
Sbjct: 72 VKTLHPKIHAGLLA 85
Score = 37.1 bits (82), Expect = 0.27
Identities = 19/39 (48%), Positives = 25/39 (64%)
Frame = +1
Query: 304 ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
I ++V L PFV VS + ++ AVE IDIGG + LRA
Sbjct: 102 IDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRA 140
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 79.8 bits (188), Expect = 4e-14
Identities = 39/74 (52%), Positives = 54/74 (72%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SVSDK L SL + L++ ++LI+SGGT ++ Q+VS+ T +PE+LGGR
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGR 71
Query: 212 VKTLHPAVHAGILA 253
VKTLHP +HAGIL+
Sbjct: 72 VKTLHPKIHAGILS 85
Score = 32.7 bits (71), Expect = 5.8
Identities = 15/48 (31%), Positives = 27/48 (56%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
++K +Y+ I +V+ PF + + + +ENID+GG T +RA
Sbjct: 95 ELKANQYDEIDLVIVNFYPFEKTLDQT-TNHSKIIENIDVGGPTMVRA 141
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 75.4 bits (177), Expect = 8e-13
Identities = 36/79 (45%), Positives = 53/79 (67%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
+ AL+SVSDKTG+ SLAK+L + ++LI + GT L G+ VS+ PE++ GR
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 212 VKTLHPAVHAGILAHYQTL 268
VKTLHP +H GIL++ + +
Sbjct: 69 VKTLHPKIHGGILSNNKNI 87
Score = 35.5 bits (78), Expect = 0.82
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = +1
Query: 283 KRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
K + I +V+ PF V K ++ + + ++NIDIGGV R+
Sbjct: 91 KNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARS 136
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 74.9 bits (176), Expect = 1e-12
Identities = 36/72 (50%), Positives = 50/72 (69%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SV K G+ LA++ + G +++++G TA L G+ V +VSD+T PE L GRVK
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVK 70
Query: 218 TLHPAVHAGILA 253
TLHP +HAGILA
Sbjct: 71 TLHPYIHAGILA 82
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 71.7 bits (168), Expect = 1e-11
Identities = 37/72 (51%), Positives = 50/72 (69%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SVSDK+ L LA+ L ++++++GGT L G+ V VS+ T APE+L GRVK
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 218 TLHPAVHAGILA 253
TLHP +H GILA
Sbjct: 77 TLHPKIHGGILA 88
Score = 45.6 bits (103), Expect = 8e-04
Identities = 21/50 (42%), Positives = 31/50 (62%)
Frame = +1
Query: 271 QXDMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
Q +++ I +V+ L PF ++KP + ADA+ENIDIGG T +RA
Sbjct: 95 QRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDIGGPTMVRA 144
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 70.9 bits (166), Expect = 2e-11
Identities = 33/72 (45%), Positives = 46/72 (63%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
AL+SV K GL + L+ G++ +++GGT + + G + V D+TR P MLGGRVK
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 218 TLHPAVHAGILA 253
TLHP + GILA
Sbjct: 71 TLHPMIFGGILA 82
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 68.1 bits (159), Expect = 1e-10
Identities = 34/80 (42%), Positives = 48/80 (60%)
Frame = +2
Query: 11 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRA 190
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 191 PEMLGGRVKTLHPAVHAGIL 250
P++L G VKTLHP + GIL
Sbjct: 75 PKILDGHVKTLHPNIQGGIL 94
>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 202
Score = 68.1 bits (159), Expect = 1e-10
Identities = 34/80 (42%), Positives = 48/80 (60%)
Frame = +2
Query: 11 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRA 190
Q+ AS K AL+S+S+K L L SL G ++++ GGT L NA ++ V +T
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 191 PEMLGGRVKTLHPAVHAGIL 250
P++L G VKTLHP + GIL
Sbjct: 75 PKILDGHVKTLHPNIQGGIL 94
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 66.9 bits (156), Expect = 3e-10
Identities = 37/75 (49%), Positives = 48/75 (64%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
ALLSVSDKTGLL LAK+L+ ++LIASGGTA L AGL V V ++ E GR+K
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMK 66
Query: 218 TLHPAVHAGILAHYQ 262
T+ + + +L Q
Sbjct: 67 TISFEIASSLLFRRQ 81
Score = 33.5 bits (73), Expect = 3.3
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +1
Query: 298 EMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
E I +VV L PF + K + +ENIDIGG T LRA
Sbjct: 95 EPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRA 134
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 65.7 bits (153), Expect = 7e-10
Identities = 32/73 (43%), Positives = 45/73 (61%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K AL+SV K GL + L E G++ +++GGT + + G + V D+T P +LGGR
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 212 VKTLHPAVHAGIL 250
VKTLHP + GIL
Sbjct: 68 VKTLHPKIFGGIL 80
Score = 35.5 bits (78), Expect = 0.82
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Frame = +1
Query: 289 QKYEM--ISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
+KYE+ I +V+ L PF V+ + AD +E IDIGG++ +RA
Sbjct: 93 EKYEIPEIDLVIVDLYPFEATVAS-GASEADIIEKIDIGGISLIRA 137
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 65.3 bits (152), Expect = 9e-10
Identities = 36/80 (45%), Positives = 49/80 (61%)
Frame = +2
Query: 35 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRV 214
LA+L+VSDK + LA L G ++A+ GT LR+ G+TV VSD+ P +LGGRV
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 215 KTLHPAVHAGILAHYQTLTR 274
KTL ++ GILA + R
Sbjct: 62 KTLTVSLMGGILARDEPADR 81
>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Thermotoga maritima
Length = 452
Score = 63.7 bits (148), Expect = 3e-09
Identities = 33/73 (45%), Positives = 45/73 (61%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K L+S+ +K L + + L E G ++ AS GTA L++ G+ DVS IT +LGG
Sbjct: 2 KRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGL 61
Query: 212 VKTLHPAVHAGIL 250
VKTLHP + AGIL
Sbjct: 62 VKTLHPEIFAGIL 74
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 63.7 bits (148), Expect = 3e-09
Identities = 29/74 (39%), Positives = 47/74 (63%)
Frame = +2
Query: 32 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGR 211
K L+SVSD + ++ +KSL ++L A+ GTA L+ + D+++ T PE++ GR
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 212 VKTLHPAVHAGILA 253
+KTLH ++A ILA
Sbjct: 68 IKTLHHKIYASILA 81
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 60.5 bits (140), Expect = 3e-08
Identities = 32/76 (42%), Positives = 46/76 (60%)
Frame = +2
Query: 26 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLG 205
N K A++SV DKT L LA L G+++I + GT L+ G+ ++D PE+LG
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 206 GRVKTLHPAVHAGILA 253
GRVK++ P + GILA
Sbjct: 62 GRVKSIDPKLAGGILA 77
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 59.3 bits (137), Expect = 6e-08
Identities = 32/71 (45%), Positives = 47/71 (66%)
Frame = +2
Query: 41 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVKT 220
L+SVSD +GL L + L+ + A+ GT L ++G+ + +SDIT ++L GRVKT
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 221 LHPAVHAGILA 253
LHPAV +GIL+
Sbjct: 61 LHPAVFSGILS 71
Score = 41.5 bits (93), Expect = 0.012
Identities = 19/50 (38%), Positives = 30/50 (60%)
Frame = +1
Query: 271 QXDMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
+ D+KR Y +V+C L F + K ++ D +ENIDIGG++ +RA
Sbjct: 78 EADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRA 124
>UniRef50_O28464 Cluster: Inosine monophosphate cyclohydrolase; n=1;
Archaeoglobus fulgidus|Rep: Inosine monophosphate
cyclohydrolase - Archaeoglobus fulgidus
Length = 157
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/71 (38%), Positives = 42/71 (59%)
Frame = +2
Query: 41 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVKT 220
L+S S K G+ LAK L+E G +++A+ GTA L+ G+ +S+IT E +KT
Sbjct: 4 LISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAE--SKSIKT 61
Query: 221 LHPAVHAGILA 253
LHP ++ I +
Sbjct: 62 LHPKIYEMIFS 72
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/48 (50%), Positives = 28/48 (58%)
Frame = +1
Query: 277 DMKRQKYEMISVVVCXLXPFVXXVSKPDVTVADAVENIDIGGVTXLRA 420
DMKR I +VV L PF V++PDVT A NIDIGG +RA
Sbjct: 106 DMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQARGNIDIGGPCMVRA 153
Score = 39.5 bits (88), Expect = 0.050
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Frame = +2
Query: 41 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATXLRN-----AGLTVQDVSDITRAPEM 199
L+SVSDKTGL L + + ++GGT + A + VSD T PE
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 200 LGGRVKTLHPAVHAGIL 250
GG VKTL ++ G+L
Sbjct: 79 QGGLVKTLDFKIYLGLL 95
>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
Putative uncharacterized protein precursor -
Stenotrophomonas maltophilia R551-3
Length = 589
Score = 37.5 bits (83), Expect = 0.20
Identities = 22/57 (38%), Positives = 28/57 (49%)
Frame = -3
Query: 211 PTPEHLRCSRDVRHILNCQAGVPKXRGGTATGDQLQATFRQTLC*RE*TRFVRNAEK 41
P H R + DV H+L+ QA + GG A G QL A RQ + T V N E+
Sbjct: 490 PAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACRQRSGQLDQTGLVGNGEE 546
>UniRef50_UPI0000DB7FED Cluster: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I);
n=1; Apis mellifera|Rep: PREDICTED: similar to
Carbamoyl-phosphate synthase [ammonia], mitochondrial
precursor (Carbamoyl-phosphate synthetase I) (CPSase I)
- Apis mellifera
Length = 202
Score = 36.7 bits (81), Expect = 0.35
Identities = 25/55 (45%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Frame = +2
Query: 14 NMASNGKLALLSV--SDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDV 172
NM +GK ALLS+ DK LL +AK L G + A+ GTA L+ AG+ Q V
Sbjct: 70 NMKKSGK-ALLSIREQDKPRLLEVAKRLITHGFSIDATLGTAKALQQAGIACQIV 123
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 36.3 bits (80), Expect = 0.47
Identities = 20/34 (58%), Positives = 21/34 (61%)
Frame = -1
Query: 417 AQXGHAADVDVLDRVRHGHVRLRYRXDEXVQXTD 316
AQ AADVDVLDRV V LR R DE +Q D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_O50236 Cluster: Carbamoyl-phosphate synthase large chain;
n=38; cellular organisms|Rep: Carbamoyl-phosphate
synthase large chain - Zymomonas mobilis
Length = 1112
Score = 35.9 bits (79), Expect = 0.62
Identities = 15/43 (34%), Positives = 30/43 (69%)
Frame = +2
Query: 53 SDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDI 181
SDK ++ K+L++ G++L+A+ GTA L++ G+ V+ V+ +
Sbjct: 988 SDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKV 1030
>UniRef50_UPI0000382898 Cluster: COG0138: AICAR transformylase/IMP
cyclohydrolase PurH (only IMP cyclohydrolase domain in
Aful); n=1; Magnetospirillum magnetotacticum MS-1|Rep:
COG0138: AICAR transformylase/IMP cyclohydrolase PurH
(only IMP cyclohydrolase domain in Aful) -
Magnetospirillum magnetotacticum MS-1
Length = 50
Score = 35.5 bits (78), Expect = 0.82
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +2
Query: 38 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGL 157
ALLSVSDKTGL A +L G++L+++ AGL
Sbjct: 4 ALLSVSDKTGLTDFAAALIGQGVELVSTAAPIARXHRAGL 43
>UniRef50_A6CPS0 Cluster: Carbamoyl-phosphate synthase large
subunit; n=1; Bacillus sp. SG-1|Rep: Carbamoyl-phosphate
synthase large subunit - Bacillus sp. SG-1
Length = 167
Score = 35.5 bits (78), Expect = 0.82
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +2
Query: 41 LLSVSDKTG--LLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDI-TRAPEML 202
LL+V+DK + LAK G Q++A+ GTA LR A + V++V I + P +L
Sbjct: 36 LLTVADKDKDEAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKIGSEGPTLL 92
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 35.5 bits (78), Expect = 0.82
Identities = 17/36 (47%), Positives = 21/36 (58%)
Frame = -1
Query: 417 AQXGHAADVDVLDRVRHGHVRLRYRXDEXVQXTDHH 310
A+ G AAD+DVLD + HG V R E V+ HH
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHH 447
>UniRef50_P77886 Cluster: Carbamoyl-phosphate synthase
pyrimidine-specific large chain; n=32; Firmicutes|Rep:
Carbamoyl-phosphate synthase pyrimidine-specific large
chain - Lactobacillus plantarum
Length = 1058
Score = 35.1 bits (77), Expect = 1.1
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +2
Query: 14 NMASNGKLAL-LSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDI 181
++ S+G + L + DK ++LAK G QL+A+ GTAT L GL V V I
Sbjct: 931 HVPSHGNVLLTVRDEDKPETVALAKRFHALGYQLLATRGTATALTTHGLPVTTVDKI 987
>UniRef50_Q53PF8 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 289
Score = 34.3 bits (75), Expect = 1.9
Identities = 17/49 (34%), Positives = 23/49 (46%)
Frame = +1
Query: 94 GMWPAVDRQWRYRHGASERRPDSSRCVGHHESTGDARGSGENFTSSGTR 240
G P R+W+ RHGA + S R G + GD+R T+ G R
Sbjct: 16 GARPCARRRWKGRHGAGAKEEASGRSDGFGVAQGDSRRVAAQGTARGER 64
>UniRef50_Q2QAL8 Cluster: Carbamoylphosphate synthase large subunit;
n=1; uncultured marine group II euryarchaeote
HF70_39H11|Rep: Carbamoylphosphate synthase large subunit
- uncultured marine group II euryarchaeote HF70_39H11
Length = 1118
Score = 34.3 bits (75), Expect = 1.9
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +2
Query: 56 DKTGLLSLAKSLSECGLQLIASGGTATXLRN 148
DK GL+ +A+SL E G +L A+ GTA LR+
Sbjct: 996 DKEGLIPMARSLQEMGFKLHATKGTARYLRD 1026
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 33.9 bits (74), Expect = 2.5
Identities = 14/19 (73%), Positives = 15/19 (78%)
Frame = +2
Query: 197 MLGGRVKTLHPAVHAGILA 253
ML G VKTLHP +H GILA
Sbjct: 1 MLDGHVKTLHPNIHGGILA 19
>UniRef50_O17153 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 170
Score = 33.1 bits (72), Expect = 4.4
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = -2
Query: 221 KFSPDPRASPVLS*CPTHLELSGRRSEAPWRYRHWRSTAGH 99
KF PR P S C T + SG +EAP +R ++TA +
Sbjct: 128 KFPATPRILPTRSSCSTACQSSGEENEAPKNHRKAQTTAAY 168
>UniRef50_A5KA45 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 4034
Score = 32.7 bits (71), Expect = 5.8
Identities = 14/26 (53%), Positives = 17/26 (65%)
Frame = +1
Query: 4 EXTEHGVKWKTSSSQRFGQNGSTLVS 81
E HGV WK S SQR+ +GST+ S
Sbjct: 3067 EAGHHGVMWKNSLSQRYHNSGSTMHS 3092
>UniRef50_Q9HR54 Cluster: Putative uncharacterized protein; n=1;
Halobacterium salinarum|Rep: Putative uncharacterized
protein - Halobacterium salinarium (Halobacterium
halobium)
Length = 598
Score = 32.7 bits (71), Expect = 5.8
Identities = 27/85 (31%), Positives = 43/85 (50%)
Frame = +2
Query: 20 ASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEM 199
A +G LA L V+ +GLL L +++ + ++ + GTA R G QD R+ +
Sbjct: 38 AVSGVLAGLVVAGSSGLLDLWRAVGYAAVVVLLATGTAVFTRGPG---QDAVQAVRSRLL 94
Query: 200 LGGRVKTLHPAVHAGILAHYQTLTR 274
G TL + AGI+A + TL +
Sbjct: 95 FGVPWGTL---LVAGIVAGFYTLVQ 116
>UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-related
protein; n=2; Proteobacteria|Rep: Probable
hemagglutinin/hemolysin-related protein - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 4106
Score = 32.3 bits (70), Expect = 7.6
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 3/55 (5%)
Frame = -2
Query: 515 TSVXFVLFDXFDYSIVVGRVTDDGDPV---VVLGXARRXVTPPMSMFSTASATVT 360
T+V F + S VV VTDD DPV +V G + TP ++ + A +T+T
Sbjct: 244 TAVAFTVDTVAPASPVVASVTDDVDPVTGAIVSGSSTNDATPTLAGTAEAGSTIT 298
>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
large subunit - Lactobacillus acidophilus
Length = 1061
Score = 32.3 bits (70), Expect = 7.6
Identities = 16/54 (29%), Positives = 26/54 (48%)
Frame = +2
Query: 56 DKTGLLSLAKSLSECGLQLIASGGTATXLRNAGLTVQDVSDITRAPEMLGGRVK 217
DK + LA+ G +L+A+ GTA AG+T V + P L +++
Sbjct: 949 DKEKVTQLARRFDRLGFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIR 1002
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 32.3 bits (70), Expect = 7.6
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = -3
Query: 202 EHLRCSRDVRHILNCQAGVPKXRGGTATGDQLQATFRQ 89
EH R + VRH + QAG+ + GG A G++L A Q
Sbjct: 507 EHFRKAGVVRHFRHGQAGLGEQLGGAAGGEELDAALVQ 544
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.131 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 446,939,848
Number of Sequences: 1657284
Number of extensions: 7626799
Number of successful extensions: 23452
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 22769
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23442
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 35822246242
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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