Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbpv0190
(837 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 139 7e-32
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 132 1e-29
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 102 1e-20
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 99 1e-19
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 99 1e-19
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 99 1e-19
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 99 1e-19
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 97 4e-19
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 97 5e-19
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 96 8e-19
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 96 8e-19
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 95 1e-18
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 94 3e-18
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 90 7e-17
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 89 1e-16
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 86 9e-16
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 85 2e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 6e-15
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 83 1e-14
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 82 1e-14
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 82 2e-14
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 79 1e-13
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 79 1e-13
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 79 1e-13
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 78 3e-13
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 77 4e-13
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 77 7e-13
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 76 1e-12
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 76 1e-12
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 75 3e-12
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 74 4e-12
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 74 4e-12
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 7e-12
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 73 1e-11
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 70 8e-11
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 68 3e-10
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 67 4e-10
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 66 1e-09
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 64 5e-09
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 63 7e-09
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 61 3e-08
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 60 5e-08
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 59 2e-07
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 55 2e-06
UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9; ... 44 0.006
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 43 0.011
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 42 0.019
UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.72
UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2; ... 37 0.72
UniRef50_Q2W3F3 Cluster: Suppressor protein SRP40; n=2; Magnetos... 35 2.2
UniRef50_Q9VV43 Cluster: TPPP family protein CG4893; n=8; Endopt... 35 2.2
UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-relate... 35 2.9
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 34 3.8
UniRef50_A7AVV8 Cluster: Kinesin, putative; n=1; Babesia bovis|R... 34 3.8
UniRef50_Q54ZP8 Cluster: Putative homeobox transcription factor;... 34 5.1
UniRef50_Q4TDB5 Cluster: Chromosome undetermined SCAF6370, whole... 33 8.9
UniRef50_Q2LEU6 Cluster: PRL2-6; n=1; Streptomyces sp. 44414|Rep... 33 8.9
UniRef50_Q7PUV5 Cluster: ENSANGP00000017516; n=2; Coelomata|Rep:... 33 8.9
>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=105; cellular organisms|Rep:
Bifunctional purine biosynthesis protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3)
(5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase) (AICAR transformylase); IMP
cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Homo sapiens (Human)
Length = 592
Score = 139 bits (337), Expect = 7e-32
Identities = 91/203 (44%), Positives = 109/203 (53%), Gaps = 3/203 (1%)
Frame = +2
Query: 56 GKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATG---ASERXPDSSRCVGHHESTGD 226
G+LAL SVSDKTGL+ A++L+ GL L+ASGGTA A D S G E G
Sbjct: 4 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLG- 62
Query: 227 ARGSGENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + AVHAGILAR D DM R + +I VV CNLYPFV+TV+ VTV +A
Sbjct: 63 --GRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA 120
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFT 586
VE IDIGGVTLLRA + ++ + S D R LALKAFT
Sbjct: 121 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT 180
Query: 587 HTSGL*LAHIRTTSGKQYSXGAN 655
HT+ A I KQYS G +
Sbjct: 181 HTAQYDEA-ISDYFRKQYSKGVS 202
>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 628
Score = 132 bits (319), Expect = 1e-29
Identities = 76/131 (58%), Positives = 85/131 (64%), Gaps = 3/131 (2%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDARG 235
ALLSVSDKTGL+ AK L + GL L+ASGGTA A D S GH E G G
Sbjct: 1 ALLSVSDKTGLVQFAKRLVDVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLG---G 57
Query: 236 SGENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ AVH GILAR S +D DM++ Y +I VVVCNLYPFV+TVS VTV DAVE
Sbjct: 58 RVKTLHPAVHGGILARKSPADTADMEKLGYSLIRVVVCNLYPFVKTVSNPSVTVEDAVEQ 117
Query: 416 IDIGGVTLLRA 448
IDIGGVTLLRA
Sbjct: 118 IDIGGVTLLRA 128
Score = 35.9 bits (79), Expect = 1.3
Identities = 15/21 (71%), Positives = 17/21 (80%)
Frame = +1
Query: 454 KNHDRVTVVCXPADYDAVAKK 516
KNH RVTVVC PADY VA++
Sbjct: 131 KNHARVTVVCDPADYPRVAEE 151
>UniRef50_Q8PYG4 Cluster: Formyltransferase
phosphoribosylaminoimidazolecarboxamide; n=4;
Methanosarcinaceae|Rep: Formyltransferase
phosphoribosylaminoimidazolecarboxamide - Methanosarcina
mazei (Methanosarcina frisia)
Length = 538
Score = 102 bits (245), Expect = 1e-20
Identities = 68/184 (36%), Positives = 103/184 (55%), Gaps = 5/184 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDA 229
K ALLSVSDKTG++ A+ L G+++I++GGTA A D S G+ E G
Sbjct: 3 KRALLSVSDKTGIVEFARGLEALGVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMG-- 60
Query: 230 RGSGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +H G+L R S E+ ++ +I ++ NLYPF TVS+ +V + +A
Sbjct: 61 -GRVKTLHPRIHGGLLCLRESKEQMEEAAKEDISLIDLIAVNLYPFEITVSRENVELEEA 119
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGR-DLALKAF 583
+ENIDIGG TLLR+ + S + ++ P+ R +E SS + + R +LA+KAF
Sbjct: 120 IENIDIGGPTLLRSAAKNYR-SVTVLSDPSDY--GRILKELRSSGIISDKTRAELAVKAF 176
Query: 584 THTS 595
HT+
Sbjct: 177 RHTA 180
>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Treponema
denticola
Length = 533
Score = 99.1 bits (236), Expect = 1e-19
Identities = 63/174 (36%), Positives = 89/174 (51%)
Frame = +2
Query: 62 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSG 241
L L SVSDKTGL A L G IASGGTA E + S G
Sbjct: 3 LVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRV 62
Query: 242 ENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
+ +H GILAR + D+ ++K + I +V+ NLYPF +T+S D T +D +ENID
Sbjct: 63 KTLHPMIHGGILARDTKEDRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENID 122
Query: 422 IGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAF 583
IGGV LLRA + + + + P ++ E+T ++ + + LA+KAF
Sbjct: 123 IGGVALLRAAAKNYS-RVTVICDPADYDEVSSEIEKT-GEISLSLRKRLAIKAF 174
>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
Bifunctional purine biosynthesis protein PurH -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 577
Score = 99.1 bits (236), Expect = 1e-19
Identities = 61/131 (46%), Positives = 78/131 (59%), Gaps = 2/131 (1%)
Frame = +2
Query: 62 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
LALLSVSDKTGL+ LA+SL E G QL++SGGTA SE + H + G
Sbjct: 17 LALLSVSDKTGLIPLAQSLVQEHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGR 76
Query: 239 GENFTSAVHAGILARLSDS-DQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ +H GILARL S D+ D++ I +VV N YPF QTV++ V++ +A E
Sbjct: 77 VKTLHPRIHGGILARLECSEDRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEAFEQ 136
Query: 416 IDIGGVTLLRA 448
IDIGG TL RA
Sbjct: 137 IDIGGPTLARA 147
>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Haemophilus influenzae
Length = 532
Score = 99.1 bits (236), Expect = 1e-19
Identities = 65/177 (36%), Positives = 93/177 (52%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
ALLSVSDKTG++ A+ L + G++L+++GGTA ++ + G +
Sbjct: 9 ALLSVSDKTGIVEFAQGLVKRGVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVK 68
Query: 245 NFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDI 424
VH GIL R +D M++ E I +VV NLYPF TV+K D T+ADAVENIDI
Sbjct: 69 TLHPKVHGGILGRRG-TDDAIMQQHGIEGIDMVVVNLYPFAATVAKPDCTLADAVENIDI 127
Query: 425 GGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHTS 595
GG T++R+ + V + +S F + DLA+KAF HT+
Sbjct: 128 GGPTMVRSAAKNHKDVAIVVNNHDFNAILAEMDQHQNSLTFETR-FDLAIKAFEHTA 183
>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacillus subtilis
Length = 512
Score = 99.1 bits (236), Expect = 1e-19
Identities = 67/183 (36%), Positives = 97/183 (53%), Gaps = 4/183 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDAR-- 232
K AL+SVSDKT L+ K L+E G+++I++GGT E D +G E TG
Sbjct: 4 KRALISVSDKTNLVPFVKELTELGVEVISTGGTKKLLQENGVD---VIGISEVTGFPEIM 60
Query: 233 -GSGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +H G+LA R ++ + + I +VV NLYPF +T+SK DVT +A
Sbjct: 61 DGRLKTLHPNIHGGLLAVRGNEEHMAQINEHGIQPIDLVVVNLYPFKETISKEDVTYEEA 120
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFT 586
+ENIDIGG +LRA + + + P NQ ++ S V + R+LA K F
Sbjct: 121 IENIDIGGPGMLRAASKNHQ-DVTVIVDPADYSPVLNQIKEEGS-VSLQKKRELAAKVFR 178
Query: 587 HTS 595
HT+
Sbjct: 179 HTA 181
>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Synechocystis sp. (strain PCC
6803)
Length = 511
Score = 97.5 bits (232), Expect = 4e-19
Identities = 57/132 (43%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARG 235
+LALLSVSDK+G++ LA+ L +E LI+SGGTA E ++ + + G
Sbjct: 3 RLALLSVSDKSGIVELAQRLVNEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGG 62
Query: 236 SGENFTSAVHAGILARLS-DSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ +H GILAR SDQ D++ + +VV NLYPF QT++K VTVA+AVE
Sbjct: 63 RVKTLHPRIHGGILARRDLPSDQADLEANDIRPLDLVVVNLYPFEQTIAKPGVTVAEAVE 122
Query: 413 NIDIGGVTLLRA 448
IDIGG ++RA
Sbjct: 123 QIDIGGPAMIRA 134
>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Azoarcus sp.
(strain BH72)
Length = 527
Score = 97.1 bits (231), Expect = 5e-19
Identities = 68/184 (36%), Positives = 96/184 (52%), Gaps = 7/184 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDARG 235
AL+SVSDK G+L A+ L+ G++L+++GGTA A D S G E G
Sbjct: 6 ALISVSDKRGVLDFARELAGLGIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLD---G 62
Query: 236 SGENFTSAVHAGILARLSDSDQED-MKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ VH GILAR ++ D + I +VV NLYPF TV++ D T+ DA+E
Sbjct: 63 RVKTLHPKVHGGILARRDLAEHMDTIAAHDISRIDLVVVNLYPFQATVARPDCTLEDAIE 122
Query: 413 NIDIGGVTLLRAXPR---TTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAF 583
NIDIGG T++RA + T G VT P + + ++ + LA+KAF
Sbjct: 123 NIDIGGPTMVRAAAKNHGTEAGGVGIVTDPEDYAGIVAELKANANTLSYKTRFALAVKAF 182
Query: 584 THTS 595
THT+
Sbjct: 183 THTA 186
>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
PurH; n=12; Bacteria|Rep: Bifunctional purine
biosynthesis protein PurH - Synechococcus sp. (strain
JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
Length = 537
Score = 96.3 bits (229), Expect = 8e-19
Identities = 59/131 (45%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Frame = +2
Query: 62 LALLSVSDKTGLLSLAKSL-SECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
LALLSVSDKTGL+ LA++L E G QL++SGGTA SE + H + G
Sbjct: 9 LALLSVSDKTGLIPLAQALVQEHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGR 68
Query: 239 GENFTSAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ +H GILARL D+ D++ I +VV N YPF QTV++ V++ +A E
Sbjct: 69 VKTLHPRIHGGILARLERREDRADLEALGIPPIQLVVVNFYPFEQTVARAGVSLEEAFEQ 128
Query: 416 IDIGGVTLLRA 448
IDIGG TL RA
Sbjct: 129 IDIGGPTLARA 139
>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
/ ATCC 700699)
Length = 492
Score = 96.3 bits (229), Expect = 8e-19
Identities = 74/211 (35%), Positives = 108/211 (51%), Gaps = 10/211 (4%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPD--SSRCVGHHESTGDAR 232
K A+LSVS+KTG++ AK+L++ +L ++GGT E S + H D R
Sbjct: 2 KKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGR 61
Query: 233 GSGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAV 409
+ AVH GILA R ++ Q ++I +VV NLYPF QTV+ DVT+ +A+
Sbjct: 62 V--KTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAI 119
Query: 410 ENIDIGGVTLLRAXPR-----TTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLAL 574
ENIDIGG T+LRA + TT P+ T L R + + +R + L +
Sbjct: 120 ENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRL-----RNDSLDESYR---QSLMI 171
Query: 575 KAFTHTSGL*LAHIRTTSGKQYS--XGANPK 661
K F HT+ A +R G + + G NP+
Sbjct: 172 KVFEHTAEYDEAIVRFFKGDKETLRYGENPQ 202
>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
n=2; Dictyostelium discoideum|Rep: AICAR transformylase
/ IMP cyclohydrolase - Dictyostelium discoideum AX4
Length = 542
Score = 95.5 bits (227), Expect = 1e-18
Identities = 63/181 (34%), Positives = 90/181 (49%), Gaps = 6/181 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
ALLSV +K+G++ +K LS G LI++GGTA + + E G +
Sbjct: 3 ALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVK 62
Query: 245 NFTSAVHAGILARLSDSD-QEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
+H G+LAR + Q D+ + + IS+VV NLYPFV+TVSK T+ +A+ENID
Sbjct: 63 TLHPKIHGGLLARPELAHHQADLNKYNIKPISIVVVNLYPFVETVSKESTTLEEAIENID 122
Query: 422 IGGVTLLRAXPRTTTG-----SPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFT 586
IGG TL+RA + PS + S + + + LALKAF
Sbjct: 123 IGGHTLIRASSKNFQNVLIIVDPSDYKWIGERIQSSTDSTNVLSSITLEERKKLALKAFQ 182
Query: 587 H 589
H
Sbjct: 183 H 183
>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Yersinia pestis
Length = 529
Score = 94.3 bits (224), Expect = 3e-18
Identities = 59/177 (33%), Positives = 94/177 (53%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
ALLSVSDK G++ A++LS+ G++L+++GGTA ++ + + G +
Sbjct: 10 ALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVK 69
Query: 245 NFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDI 424
VH GIL R D M + + I +VV NLYPF QTV++ D ++ DAVENIDI
Sbjct: 70 TLHPKVHGGILGRRGQDDGI-MAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDI 128
Query: 425 GGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHTS 595
GG T++R+ + + V + + + + + +LA+KAF HT+
Sbjct: 129 GGPTMVRSAAKNHK-DVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTA 184
>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Leptospira interrogans
Length = 511
Score = 89.8 bits (213), Expect = 7e-17
Identities = 58/180 (32%), Positives = 99/180 (55%), Gaps = 1/180 (0%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
K AL+SVSDK+GL+ AK L++ G+++I++GGT + + + G
Sbjct: 5 KRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGR 64
Query: 239 GENFTSAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ VH G+L +S+ + ++ M+ K I +VV NLYPF++TVSK +V + +A+EN
Sbjct: 65 VKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLVVVNLYPFLKTVSKPEVQLEEAIEN 124
Query: 416 IDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHTS 595
IDIGG +++R+ + + +T P ++ Q +SS + KAF+HT+
Sbjct: 125 IDIGGPSMIRSAAKNYKHT-LVLTDPNDY--KKIQNLISSSGISEEISASYMRKAFSHTA 181
>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Oceanobacillus iheyensis
Length = 510
Score = 89.4 bits (212), Expect = 1e-16
Identities = 64/184 (34%), Positives = 94/184 (51%), Gaps = 5/184 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDAR-- 232
K AL+SVSDKT ++ AK L E G +++++GGT +E D + E TG
Sbjct: 3 KRALISVSDKTNIIEFAKGLKESGFEILSTGGTLRSIAEAGIDVTPV---DEVTGFPEML 59
Query: 233 -GSGENFTSAVHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +H G+L + S+ + M+ I +V NLYPF +TV K DV+ D
Sbjct: 60 DGRVKTLHPMIHGGLLGKRSNHEHLSQMEEHGIRSIDLVAVNLYPFKETVQKPDVSHQDI 119
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTS-SDVFRAQGRDLALKAF 583
+ENIDIGG ++LR+ + VT PT R TS +D + + + LA K F
Sbjct: 120 IENIDIGGPSMLRSAAKNFE-DVLVVTGPTDY--NRVLAAITSETDTYEFR-QQLAAKVF 175
Query: 584 THTS 595
HT+
Sbjct: 176 RHTA 179
>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase; n=4;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase /IMP cyclohydrolase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 530
Score = 86.2 bits (204), Expect = 9e-16
Identities = 55/132 (41%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RXPDSSRCVGHHESTGDARG 235
ALLSVSDKTGL+ A+SL+ G++LI++GGTA ++ + D S G E G
Sbjct: 11 ALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMD---G 67
Query: 236 SGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ VH G+LA R +D E MK I ++V NLYPF TV + +D +E
Sbjct: 68 RVKTLHPKVHGGLLAIRGNDEHAEAMKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIE 126
Query: 413 NIDIGGVTLLRA 448
NIDIGG ++RA
Sbjct: 127 NIDIGGPAMIRA 138
Score = 46.4 bits (105), Expect = 9e-04
Identities = 20/33 (60%), Positives = 27/33 (81%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
+A+ +AGL V+DVSD+T PEM+ GRVKTLH +
Sbjct: 43 KAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPK 75
>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=214; cellular organisms|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Xylella fastidiosa
Length = 527
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/131 (40%), Positives = 74/131 (56%), Gaps = 3/131 (2%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERX---PDSSRCVGHHESTGDARG 235
ALLSVSDKTGL+ LA++L ++L+++GGTAT E D + G E G
Sbjct: 11 ALLSVSDKTGLVELARALLAYNIELLSTGGTATIIREAGLPVQDVADLTGFPEMMD---G 67
Query: 236 SGENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ VH G+L R + D M + I +++ NLYPF Q +K D T+ADAV+
Sbjct: 68 RVKTLHPMVHGGLLGR-AGIDDAVMAKHGIAPIDLLILNLYPFEQITAKKDCTLADAVDT 126
Query: 416 IDIGGVTLLRA 448
IDIGG +LR+
Sbjct: 127 IDIGGPAMLRS 137
>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Streptococcus suis
Length = 515
Score = 85.0 bits (201), Expect = 2e-15
Identities = 63/186 (33%), Positives = 99/186 (53%), Gaps = 7/186 (3%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDAR-- 232
K AL+SVSDK G++ A+ L++ G ++I++GGT + + + + TG
Sbjct: 3 KRALISVSDKNGIVEFAQELTKFGWEIISTGGTKVALDQAGVTT---IAIDDVTGFPEMM 59
Query: 233 -GSGENFTSAVHAGILARLS-DSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +H G+LAR DS + + +I +VV NLYPF +T+ + DVT A
Sbjct: 60 DGRVKTLHPKIHGGLLARRDLDSHLQAANDHEIGLIDLVVVNLYPFKETILRPDVTYDLA 119
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPT---TML*QRNQREQTSSDVFRAQGRDLALK 577
VENIDIGG ++LR+ + S + V P T+L + ++ +TS A + LA K
Sbjct: 120 VENIDIGGPSMLRSAAK-NHASVTVVVDPADYPTVLGEIAEQGETS----YATRQRLAAK 174
Query: 578 AFTHTS 595
F HT+
Sbjct: 175 VFRHTA 180
>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=5; Coxiella
burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Coxiella burnetii
Length = 526
Score = 83.4 bits (197), Expect = 6e-15
Identities = 48/130 (36%), Positives = 72/130 (55%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
K AL+S +DK GL+ L CG+++IA+GGTA + + G
Sbjct: 12 KRALISTADKIGLIEFISQLVTCGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGR 71
Query: 239 GENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENI 418
+ +HAG+LAR D++ + + + I ++V NLYPFVQTVS + ++ AVE I
Sbjct: 72 VKTLHPKIHAGLLARRG-IDEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQI 130
Query: 419 DIGGVTLLRA 448
DIGG ++LRA
Sbjct: 131 DIGGPSMLRA 140
>UniRef50_A6G003 Cluster: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
pacifica SIR-1|Rep: Bifunctional
phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Plesiocystis
pacifica SIR-1
Length = 543
Score = 82.6 bits (195), Expect = 1e-14
Identities = 54/177 (30%), Positives = 91/177 (51%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
AL+SVSDK+ L LA+ L ++++++GGT SE + + G +
Sbjct: 17 ALVSVSDKSKLDVLAEILIAHKVEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVK 76
Query: 245 NFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDI 424
+H GILA +++ Q +++ I +V+ NLYPF +T++K + ADA+ENIDI
Sbjct: 77 TLHPKIHGGILALPTEAHQRELELHDIAPIDLVIVNLYPFRETIAKPGCSFADAIENIDI 136
Query: 425 GGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHTS 595
GG T++RA + + + P +T + + R++A KAF HT+
Sbjct: 137 GGPTMVRAAAK-NWNRVAVIVDPEDYSSLSEVLGETEGTLPESFRRNMARKAFAHTA 192
>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
bacteriovorus
Length = 507
Score = 82.2 bits (194), Expect = 1e-14
Identities = 56/130 (43%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDA-RGSG 241
ALLSVSDKTGLL LAK+L+ ++LIASGGTA +E + V G+A G
Sbjct: 7 ALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVT-AVETLSGKGEAFNGRM 65
Query: 242 ENFTSAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENI 418
+ + + + +L R D +D E I +VV NLYPF T+ K + +ENI
Sbjct: 66 KTISFEIASSLLFRRQDENDVRQAAELGIEPIDLVVVNLYPFHATLQK-QAGFEECIENI 124
Query: 419 DIGGVTLLRA 448
DIGG TLLRA
Sbjct: 125 DIGGPTLLRA 134
>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
Length = 506
Score = 81.8 bits (193), Expect = 2e-14
Identities = 54/132 (40%), Positives = 72/132 (54%), Gaps = 4/132 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDS---SRCVGHHESTGDARG 235
AL+SV DKTG+L LAK L G ++++SGGT T D+ S G E G G
Sbjct: 3 ALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILG---G 59
Query: 236 SGENFTSAVHAGILARLS-DSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ A+H GIL R + D E++K E I +VV NLYPF + + + + VE
Sbjct: 60 RVKTLHPAIHGGILFREDVEKDLEEIKENSIEPIDIVVVNLYPFEKKMKELK-DIDALVE 118
Query: 413 NIDIGGVTLLRA 448
IDIGG TL+RA
Sbjct: 119 FIDIGGPTLVRA 130
>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=2; Tropheryma whipplei|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 542
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/183 (32%), Positives = 92/183 (50%), Gaps = 4/183 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDA 229
K AL+SVSDK+GL LA++L+ ++++++G TA G S D S G E
Sbjct: 8 KRALISVSDKSGLADLAEALAAHSVKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLD-- 65
Query: 230 RGSGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +HA ILA S + +++ + +VV NLYPF + + +D
Sbjct: 66 -GRVKTLHPKIHAPILADTTSQMHRAQLQQLGVDAFDLVVVNLYPFFEISKNSEAEFSDV 124
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFT 586
+E IDIGG L+RA + T + P+ + N E+ + R Q LA+KA++
Sbjct: 125 IEQIDIGGSALIRAAAKNHT-RVVVIVDPSDYIHVINSLERGAPSRLRHQ---LAIKAYS 180
Query: 587 HTS 595
HTS
Sbjct: 181 HTS 183
>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
purine biosynthesis protein - Candidatus Pelagibacter
ubique HTCC1002
Length = 518
Score = 79.0 bits (186), Expect = 1e-13
Identities = 57/185 (30%), Positives = 102/185 (55%), Gaps = 6/185 (3%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RXPDSSRCVGHHESTGDA 229
K AL+SVSDK L SL + L++ ++LI+SGGT + + + S G E G
Sbjct: 12 KKALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILG-- 69
Query: 230 RGSGENFTSAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +HAGIL++ +D S +++K +Y+ I +V+ N YPF +T+ + +
Sbjct: 70 -GRVKTLHPKIHAGILSKRNDKSHTKELKANQYDEIDLVIVNFYPFEKTLDQ-TTNHSKI 127
Query: 407 VENIDIGGVTLLRAXPRTTTGSP--SSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKA 580
+ENID+GG T++RA + +S + T++ + + ++S FR + ++L+A
Sbjct: 128 IENIDVGGPTMVRAAAKNYNDVTVITSSDQYETLINELENNKGSTSIEFREK---MSLEA 184
Query: 581 FTHTS 595
F+ T+
Sbjct: 185 FSETA 189
Score = 36.7 bits (81), Expect = 0.72
Identities = 15/23 (65%), Positives = 20/23 (86%)
Frame = +3
Query: 192 QDVSDITRAPEMLGGRVKTLHQR 260
Q+VS+ T +PE+LGGRVKTLH +
Sbjct: 56 QEVSEYTGSPEILGGRVKTLHPK 78
>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
nodosum Rt17-B1|Rep: IMP cyclohydrolase -
Fervidobacterium nodosum Rt17-B1
Length = 429
Score = 79.0 bits (186), Expect = 1e-13
Identities = 57/136 (41%), Positives = 74/136 (54%), Gaps = 4/136 (2%)
Frame = +2
Query: 53 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTA---TGASERXPDSSRCVGHHESTG 223
N K AL+SVSDK GL+ AK+L + G+++I++GGTA + A S G E G
Sbjct: 2 NIKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILG 61
Query: 224 DARGSGENFTSAVHAGILARLSD-SDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVA 400
G + + GILA L D S +D++ E I +VV NLYPF V K
Sbjct: 62 ---GRVKTLHPKIFGGILADLGDKSHVKDLRDNFIEPIDLVVVNLYPF-DEVQKKTRDED 117
Query: 401 DAVENIDIGGVTLLRA 448
+ENIDIGGV LLRA
Sbjct: 118 VLIENIDIGGVALLRA 133
Score = 44.4 bits (100), Expect = 0.004
Identities = 19/33 (57%), Positives = 26/33 (78%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
+ L +AG+ V+ VSD+T PE+LGGRVKTLH +
Sbjct: 38 KLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPK 70
Score = 33.9 bits (74), Expect = 5.1
Identities = 14/20 (70%), Positives = 14/20 (70%)
Frame = +1
Query: 454 KNHDRVTVVCXPADYDAVAK 513
KNH V VVC PADYD V K
Sbjct: 136 KNHRNVVVVCDPADYDKVIK 155
>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 614
Score = 78.2 bits (184), Expect = 2e-13
Identities = 63/189 (33%), Positives = 95/189 (50%), Gaps = 5/189 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDA 229
K AL+SV DKTGL LA++L E G++++++G TA A G E
Sbjct: 17 KRALISVYDKTGLEDLARALGEAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVL--- 73
Query: 230 RGSGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADA 406
G + +H+GILA + + +E + + + +VVCNLYPF TV+ + +
Sbjct: 74 EGRVKTLHPFIHSGILADQRKAAHREQIAQLGIQAFDLVVCNLYPFQDTVAS-GASFDEC 132
Query: 407 VENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFR-AQGRDLALKAF 583
VE IDIGG +++RA + S + VT P + E + + F Q R LA +AF
Sbjct: 133 VEQIDIGGPSMVRAAAKNHP-SVAVVTSPER---YADVAEAVAGEGFTLEQRRVLAAEAF 188
Query: 584 THTSGL*LA 610
HT+ LA
Sbjct: 189 AHTATYDLA 197
Score = 35.9 bits (79), Expect = 1.3
Identities = 16/26 (61%), Positives = 19/26 (73%)
Frame = +3
Query: 177 AGLTVQDVSDITRAPEMLGGRVKTLH 254
AG+ V V D+T PE+L GRVKTLH
Sbjct: 56 AGVAVTPVDDVTGFPEVLEGRVKTLH 81
>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
uncultured Acidobacteria bacterium|Rep: Putative AICAR
transformylase - uncultured Acidobacteria bacterium
Length = 571
Score = 77.8 bits (183), Expect = 3e-13
Identities = 47/132 (35%), Positives = 72/132 (54%), Gaps = 4/132 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RXPDSSRCVGHHESTGDARG 235
AL+SVSDKTG++ A L ++++++GGTA E D S G E G
Sbjct: 15 ALISVSDKTGIVDFASELRAFDIEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMD---G 71
Query: 236 SGENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ +H G+L R S S + M+ E I +VV +LYPF +T+ V++A+A+E
Sbjct: 72 RVKTLHPKIHGGLLGVRDSPSHESSMREHGIEPIDMVVIDLYPFERTIKGAAVSLAEAIE 131
Query: 413 NIDIGGVTLLRA 448
IDIGG ++R+
Sbjct: 132 QIDIGGPAMIRS 143
>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=2;
Arthrobacter|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
(strain FB24)
Length = 559
Score = 77.4 bits (182), Expect = 4e-13
Identities = 64/193 (33%), Positives = 90/193 (46%), Gaps = 1/193 (0%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
AL+SV DKTGL LAK L E G++++++G TA + S G +
Sbjct: 14 ALISVYDKTGLEELAKGLHEAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVK 73
Query: 245 NFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
VH GILA R + E + + E +VV NLYPFV+TV K D VE ID
Sbjct: 74 TLHPRVHGGILADRRVPAHMETLAGMEIEAFDLVVVNLYPFVETV-KSGAAQDDVVEQID 132
Query: 422 IGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHTSGL 601
IGG ++R+ + + + VT P + D+ Q LA KAF HT+
Sbjct: 133 IGGPAMVRSAAK-NHAAVAIVTDPNFYGDVVRAAAEGGFDLKTRQ--RLAAKAFAHTASY 189
Query: 602 *LAHIRTTSGKQY 640
A + T + Q+
Sbjct: 190 DTA-VATWTASQF 201
Score = 42.7 bits (96), Expect = 0.011
Identities = 18/28 (64%), Positives = 23/28 (82%)
Frame = +3
Query: 177 AGLTVQDVSDITRAPEMLGGRVKTLHQR 260
AG+ VQ+V ++T +PEML GRVKTLH R
Sbjct: 51 AGIPVQEVEEVTGSPEMLDGRVKTLHPR 78
>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=14;
Viridiplantae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
(Common tobacco)
Length = 612
Score = 76.6 bits (180), Expect = 7e-13
Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = +2
Query: 38 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHES 217
++ S K AL+S+SDKT L L L E G ++++GGT++ ++
Sbjct: 82 KSSTSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRF 141
Query: 218 TGDARGSGENFTSAVHAGILARL-SDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXD-V 391
G + +VH GILAR + E +++ + VVV NLYPF VS +
Sbjct: 142 PEMLDGRVKTLHPSVHGGILARRDQEHHMEALEKHEIGTFDVVVVNLYPFYAKVSSSSGI 201
Query: 392 TVADAVENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLA 571
+ D +ENIDIGG ++RA + V R FR R LA
Sbjct: 202 SFEDGIENIDIGGPAMIRAAAKNHRDVLVVVDSEDYPALLEFLRGDNDDQQFR---RKLA 258
Query: 572 LKAFTHTS 595
KAF H +
Sbjct: 259 WKAFQHVA 266
Score = 42.3 bits (95), Expect = 0.014
Identities = 19/30 (63%), Positives = 23/30 (76%)
Frame = +3
Query: 165 ALRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
AL AG++V V ++TR PEML GRVKTLH
Sbjct: 124 ALEGAGVSVTKVEELTRFPEMLDGRVKTLH 153
>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Deinococcus radiodurans
Length = 510
Score = 76.2 bits (179), Expect = 1e-12
Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGG---TATGASERXPDSSRCVGHHESTGDA 229
K AL+SVSDKTG++ A L + G +L+++GG T +GA S G E
Sbjct: 3 KRALISVSDKTGVVEFAAQLQQRGWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLD-- 60
Query: 230 RGSGENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAV 409
G + A+H GILAR + Q I +V NLYPF +TV++ + +
Sbjct: 61 -GRVKTLHPAIHGGILARREAGHLGQLAAQDIGTIDLVCVNLYPFRETVAR-GAPDPEVI 118
Query: 410 ENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTH 589
ENIDIGG ++R+ + V L +V A+ R LA KA+ H
Sbjct: 119 ENIDIGGPAMIRSAAKNHDAVLVLVDPADYAL-------ALQDEVSPAERRRLAAKAYRH 171
Query: 590 TS 595
TS
Sbjct: 172 TS 173
Score = 41.9 bits (94), Expect = 0.019
Identities = 19/29 (65%), Positives = 22/29 (75%)
Frame = +3
Query: 168 LRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
L AG+ V+ VSD+T PEML GRVKTLH
Sbjct: 39 LSGAGIPVRQVSDVTGFPEMLDGRVKTLH 67
>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Wigglesworthia glossinidia
brevipalpis
Length = 529
Score = 75.8 bits (178), Expect = 1e-12
Identities = 43/130 (33%), Positives = 72/130 (55%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
+ AL+SVSDKTG+ SLAK+L + ++LI + GT E+ S+ + G
Sbjct: 9 RCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGR 68
Query: 239 GENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENI 418
+ +H GIL+ ++ + + K + I +V+ N YPF + V K ++ + + ++NI
Sbjct: 69 VKTLHPKIHGGILS--NNKNINENKNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNI 126
Query: 419 DIGGVTLLRA 448
DIGGV L R+
Sbjct: 127 DIGGVALARS 136
>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Aquifex aeolicus
Length = 506
Score = 74.5 bits (175), Expect = 3e-12
Identities = 50/132 (37%), Positives = 74/132 (56%), Gaps = 4/132 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASER---XPDSSRCVGHHESTGDARG 235
A++SV K G+ LAK+L E G +++++GGTA E+ + S G E G
Sbjct: 3 AIISVYRKEGIDKLAKALQELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEI---LEG 59
Query: 236 SGENFTSAVHAGILAR-LSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ VH GIL R + D+E++++ + I VVV NLYPF + + K +T D +E
Sbjct: 60 RVKTLHPVVHGGILFRDWVEKDKEEIEKHGIKPIDVVVVNLYPFEEKL-KEGLTDKDLME 118
Query: 413 NIDIGGVTLLRA 448
IDIGG TL+RA
Sbjct: 119 FIDIGGPTLIRA 130
Score = 40.7 bits (91), Expect = 0.044
Identities = 18/29 (62%), Positives = 24/29 (82%)
Frame = +3
Query: 168 LRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
LR G++V++VS+IT PE+L GRVKTLH
Sbjct: 37 LREKGISVKEVSEITGFPEILEGRVKTLH 65
>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Methanomicrobiales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 497
Score = 74.1 bits (174), Expect = 4e-12
Identities = 46/129 (35%), Positives = 70/129 (54%)
Frame = +2
Query: 62 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSG 241
LALLSV DKTG+L LA++L + +++SGGTA E + + + G
Sbjct: 3 LALLSVWDKTGILDLARALVAKNIGILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRV 62
Query: 242 ENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
+ VH G+L R D + MK E I ++ NLYPF + +SK ++ + + +E ID
Sbjct: 63 KTLHPKVHGGLLGR-RGIDDDVMKAHFIEPIDILCVNLYPF-EEMSKKNLPLEELIEFID 120
Query: 422 IGGVTLLRA 448
IGG ++RA
Sbjct: 121 IGGPAMIRA 129
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/33 (57%), Positives = 26/33 (78%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
+ALR AG+ +DVS+ T+ PEM+ GRVKTLH +
Sbjct: 36 KALREAGIPAKDVSEYTQFPEMMDGRVKTLHPK 68
>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Clostridium perfringens
Length = 501
Score = 74.1 bits (174), Expect = 4e-12
Identities = 49/131 (37%), Positives = 71/131 (54%), Gaps = 1/131 (0%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
K AL+SV DK G+L LAK L + +++I+SGGT E + + G
Sbjct: 3 KRALISVFDKDGVLELAKFLRDRDVEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGR 62
Query: 239 GENFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVEN 415
+ VHAGILA R + + ++ ++ I VV NLYPF + V + D++ + VE
Sbjct: 63 VKTLHPLVHAGILAIRDNKEHMKTLEEREINTIDYVVVNLYPFFEKV-REDLSFEEKVEF 121
Query: 416 IDIGGVTLLRA 448
IDIGG T+LRA
Sbjct: 122 IDIGGPTMLRA 132
>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=3;
Alphaproteobacteria|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methylobacterium
extorquens PA1
Length = 581
Score = 73.3 bits (172), Expect = 7e-12
Identities = 48/129 (37%), Positives = 67/129 (51%), Gaps = 1/129 (0%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
ALLSVSDKTGL A +LS+ G++L+++GGT +E G +
Sbjct: 60 ALLSVSDKTGLTDFAAALSQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVK 119
Query: 245 NFTSAVHAGILA-RLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
AVH G+LA R + Q + I ++V NLYPF +T+ K D VENID
Sbjct: 120 TLHPAVHGGLLAVRDNPEHQAALAAHGIGAIDLLVVNLYPFEETL-KAGKAYDDCVENID 178
Query: 422 IGGVTLLRA 448
+GG ++RA
Sbjct: 179 VGGPAMIRA 187
Score = 47.6 bits (108), Expect = 4e-04
Identities = 21/31 (67%), Positives = 26/31 (83%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
RAL AGL V++VS++TR PEM+ GRVKTLH
Sbjct: 92 RALTEAGLAVREVSELTRFPEMMDGRVKTLH 122
>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 225
Score = 72.5 bits (170), Expect = 1e-11
Identities = 60/184 (32%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Frame = +2
Query: 68 LLSVSDKTGLLSLAKSLSECG--LQLIASGGTATGASERXPDSSRCVGHHES--TGDARG 235
L+SVSDKTGL L + + ++GGT E +++ V S TG
Sbjct: 19 LISVSDKTGLEEFVTRLVRINPDVHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPET 78
Query: 236 SG---ENFTSAVHAGILARL-SDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVAD 403
G + ++ G+L ++S DMKR I +VV NLYPF QTV++ DVT
Sbjct: 79 QGGLVKTLDFKIYLGLLTETYNESHARDMKRTGAVAIDMVVVNLYPFSQTVARPDVTPEQ 138
Query: 404 AVENIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAF 583
A NIDIGG ++RA + +SV P ++ E + +LA KAF
Sbjct: 139 ARGNIDIGGPCMVRASAKNFL-RVASVVDPADYNTVADEMEHRQGALSLDTRFELAQKAF 197
Query: 584 THTS 595
HT+
Sbjct: 198 DHTA 201
>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=1; Candidatus
Methanoregula boonei 6A8|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Methanoregula
boonei (strain 6A8)
Length = 525
Score = 69.7 bits (163), Expect = 8e-11
Identities = 47/133 (35%), Positives = 70/133 (52%), Gaps = 3/133 (2%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTAT---GASERXPDSSRCVGHHESTGDA 229
K ALLSV DKTG++ LA++L + +++SGGT T GA + SR G E
Sbjct: 32 KWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMD-- 89
Query: 230 RGSGENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAV 409
G + VH G+L R D M + I ++V NLYPF + +S+ + + +
Sbjct: 90 -GRVKTLHPKVHGGLLGR-RQIDDAIMAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLI 146
Query: 410 ENIDIGGVTLLRA 448
E ID+GG ++RA
Sbjct: 147 EYIDVGGPAMIRA 159
>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Thermoplasmatales|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Picrophilus torridus
Length = 494
Score = 67.7 bits (158), Expect = 3e-10
Identities = 43/127 (33%), Positives = 66/127 (51%)
Frame = +2
Query: 68 LLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGEN 247
L+SVSD +GL L + L+ + A+ GT S+ + R G +
Sbjct: 4 LVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKT 60
Query: 248 FTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDIG 427
AV +GIL+R + + D+KR Y +V+CNLY F + K ++ D +ENIDIG
Sbjct: 61 LHPAVFSGILSRRDEQSEADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIG 117
Query: 428 GVTLLRA 448
G++L+RA
Sbjct: 118 GLSLIRA 124
>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
Bifunctional purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Campylobacter jejuni
Length = 510
Score = 67.3 bits (157), Expect = 4e-10
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 1/129 (0%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
ALLSVSDK G++ K L G +++++GGT E +S G +
Sbjct: 3 ALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVK 62
Query: 245 NFTSAVHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
+H GIL + SD + + K + I +V NLYPF +T D + +ENID
Sbjct: 63 TLHPKIHGGILHKRSDENHIKQAKENEILGIDLVCVNLYPFKKTTIMSD-DFDEIIENID 121
Query: 422 IGGVTLLRA 448
IGG ++R+
Sbjct: 122 IGGPAMIRS 130
Score = 39.1 bits (87), Expect = 0.14
Identities = 16/33 (48%), Positives = 24/33 (72%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
+ L+ G+ V +VSD T++PE+ GRVKTLH +
Sbjct: 35 KLLKENGIKVIEVSDFTKSPELFEGRVKTLHPK 67
>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=4; Desulfovibrionaceae|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Desulfovibrio desulfuricans (strain
G20)
Length = 252
Score = 66.1 bits (154), Expect = 1e-09
Identities = 56/183 (30%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPD---SSRCVGHHESTGDARG 235
ALLSV+DK+GL+ A L++ G++L+++GGT +E D S+ G E G G
Sbjct: 62 ALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMG---G 118
Query: 236 SGENFTSAVHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ +H GILA + + +K ++ NLY F ++ + + AVE
Sbjct: 119 RVKTLHPHIHGGILADKDNPEHLATLKELGIRTFDLICVNLYNFADAAAR-GLDLRGAVE 177
Query: 413 NIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSD--VFRAQGRDLALKAFT 586
+DIGG +LRA T S + P Q +E +D V A + +A+K F
Sbjct: 178 EVDIGGPCMLRA---TAKNFHSMLVLPDPADYQAAMQEMRDNDMRVGLAMRQAMAVKTFR 234
Query: 587 HTS 595
TS
Sbjct: 235 ATS 237
Score = 41.1 bits (92), Expect = 0.033
Identities = 19/31 (61%), Positives = 22/31 (70%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
R L AGL V VS +T PE++GGRVKTLH
Sbjct: 94 RTLTEAGLDVTPVSKVTGFPEIMGGRVKTLH 124
>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bifidobacterium longum
Length = 545
Score = 63.7 bits (148), Expect = 5e-09
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 4/181 (2%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASE---RXPDSSRCVGHHESTGDARG 235
AL+SV K G+ LA++ + G +++++G TA +E + + S G E G
Sbjct: 11 ALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLD---G 67
Query: 236 SGENFTSAVHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ +HAGILA +++ + + ++ + +VV NLYPF TV + AD +E
Sbjct: 68 RVKTLHPYIHAGILADMTNPEHAKQLEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIE 126
Query: 413 NIDIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHT 592
IDIGG +++R + + + VT P + R + + + LA KAF HT
Sbjct: 127 KIDIGGPSMVRGAAK-NHATVAIVTDPADYALVAS-RVADGTGFSLDERKWLAAKAFAHT 184
Query: 593 S 595
+
Sbjct: 185 A 185
Score = 37.5 bits (83), Expect = 0.41
Identities = 17/31 (54%), Positives = 21/31 (67%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
+ L G+ V +VSD+T PE L GRVKTLH
Sbjct: 43 KKLAELGVKVTEVSDVTGFPECLDGRVKTLH 73
>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
pistaciae)|Rep: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Buchnera aphidicola subsp.
Baizongia pistaciae
Length = 529
Score = 63.3 bits (147), Expect = 7e-09
Identities = 44/178 (24%), Positives = 84/178 (47%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
K L+SVSD + ++ +KSL ++L A+ GTA + ++ + G
Sbjct: 8 KNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGR 67
Query: 239 GENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENI 418
+ ++A ILA+ D++ +++ ++ +VV N YPF + + ++ + D +E+I
Sbjct: 68 IKTLHHKIYASILAQ-PKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHI 126
Query: 419 DIGGVTLLRAXPRTTTGSPSSVTRPTTML*QRNQREQTSSDVFRAQGRDLALKAFTHT 592
DIGG ++RA + + VT+P N+ ++ + A AF HT
Sbjct: 127 DIGGPAIVRAAAKNYK-NVLVVTQPNLYQSIVNEMNLNNNIISETTKLKFATIAFKHT 183
>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
purH [Includes: Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
purine biosynthesis protein purH [Includes:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) (AICAR transformylase);
IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
synthetase) (ATIC)] - Bacteroides thetaiotaomicron
Length = 507
Score = 61.3 bits (142), Expect = 3e-08
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 2/132 (1%)
Frame = +2
Query: 59 KLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGS 238
K AL+SV K GL + L E G++ +++GGT G
Sbjct: 8 KTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGR 67
Query: 239 GENFTSAVHAGILARLSDSDQEDMKRQKYEM--ISVVVCNLYPFVQTVSKXDVTVADAVE 412
+ + GIL R D +Q+ + +KYE+ I +V+ +LYPF TV+ + AD +E
Sbjct: 68 VKTLHPKIFGGILCR-RDLEQDIQQIEKYEIPEIDLVIVDLYPFEATVASG-ASEADIIE 125
Query: 413 NIDIGGVTLLRA 448
IDIGG++L+RA
Sbjct: 126 KIDIGGISLIRA 137
Score = 33.9 bits (74), Expect = 5.1
Identities = 14/31 (45%), Positives = 20/31 (64%)
Frame = +3
Query: 168 LRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
+ + G + V D+T P +LGGRVKTLH +
Sbjct: 44 IESLGYPCKAVEDLTTYPSILGGRVKTLHPK 74
>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Petrotoga mobilis SJ95
Length = 489
Score = 60.5 bits (140), Expect = 5e-08
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 1/133 (0%)
Frame = +2
Query: 53 NGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDAR 232
N K A++SV DKT L LA L G+++I + GT E+ + + +
Sbjct: 2 NIKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILG 61
Query: 233 GSGENFTSAVHAGILARLSDSD-QEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAV 409
G ++ + GILA+ +D +EDM + I +VV N +P + ++K +
Sbjct: 62 GRVKSIDPKLAGGILAKSNDKKHEEDMINYNIKRIDMVVGN-FPTFEEIAKKTKNEETLL 120
Query: 410 ENIDIGGVTLLRA 448
ENIDIGG +LLRA
Sbjct: 121 ENIDIGGYSLLRA 133
>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain; n=2; Candidatus Blochmannia|Rep:
Phosphoribosylaminoimidazolecarboxamide
formyltransferase, IMP cyclohydrolase and MGS-like
domain - Blochmannia floridanus
Length = 549
Score = 58.8 bits (136), Expect = 2e-07
Identities = 38/128 (29%), Positives = 64/128 (50%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
AL+SV DK+ LL +KSLS G++L+++ GTA + ++ + G +
Sbjct: 10 ALISVFDKSNLLHFSKSLSHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVK 69
Query: 245 NFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDI 424
+ AGIL+R + D+ + + + I +V+ N YPF + +E IDI
Sbjct: 70 TLHHKICAGILSR-KNLDESIIHKYGIQPIDMVIVNFYPFHLILQNKQHDSEKILEYIDI 128
Query: 425 GGVTLLRA 448
GG ++RA
Sbjct: 129 GGPNMVRA 136
Score = 42.7 bits (96), Expect = 0.011
Identities = 18/31 (58%), Positives = 23/31 (74%)
Frame = +3
Query: 168 LRNAGLTVQDVSDITRAPEMLGGRVKTLHQR 260
L NAGLTV +SD T PE++ G+VKTLH +
Sbjct: 44 LTNAGLTVNKISDYTNFPEIMNGQVKTLHHK 74
>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase; n=24;
Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 508
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Frame = +2
Query: 65 ALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGE 244
AL+SV K GL + L+ G++ +++GGT + G +
Sbjct: 11 ALISVYHKEGLAEILAELNRQGVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVK 70
Query: 245 NFTSAVHAGILARLS-DSDQEDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVENID 421
+ GILAR +SD ++ +I +V+ +LYPF TV+ + D +E ID
Sbjct: 71 TLHPMIFGGILARRGHESDVREVGEYGLPLIDLVIVDLYPFEATVASG-ASEEDIIEKID 129
Query: 422 IGGVTLLR 445
IGG++L+R
Sbjct: 130 IGGISLIR 137
Score = 37.5 bits (83), Expect = 0.41
Identities = 16/29 (55%), Positives = 20/29 (68%)
Frame = +3
Query: 168 LRNAGLTVQDVSDITRAPEMLGGRVKTLH 254
+ + G + V D+TR P MLGGRVKTLH
Sbjct: 45 ITSLGYACRAVDDLTRYPSMLGGRVKTLH 73
>UniRef50_Q3JNS9 Cluster: Putative uncharacterized protein; n=9;
Burkholderia|Rep: Putative uncharacterized protein -
Burkholderia pseudomallei (strain 1710b)
Length = 917
Score = 43.6 bits (98), Expect = 0.006
Identities = 23/34 (67%), Positives = 24/34 (70%)
Frame = -3
Query: 445 AQEGHAADVDVLDRVRXGHVXLRYRLDERVQVTD 344
AQ AADVDVLDRV V LR RLDER+QV D
Sbjct: 723 AQHRRAADVDVLDRVGERAVVLRNRLDERIQVHD 756
>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_19, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 227
Score = 42.7 bits (96), Expect = 0.011
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Frame = +2
Query: 38 QNMASNGKLALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHES 217
Q+ AS K AL+S+S+K L L SL G ++++ GGT +++
Sbjct: 15 QSTASGNKQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCF 74
Query: 218 TGDARGSGENFTSAVHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDV 391
G + + GIL R E + VVV NLYPF K +
Sbjct: 75 PKILDGHVKTLHPNIQGGILPRRDQKHHMEALNEHGIGTFDVVVVNLYPFYDKQPKLTI 133
>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
formyltransferase; n=1; Salinispora arenicola
CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
formyltransferase - Salinispora arenicola CNS205
Length = 190
Score = 41.9 bits (94), Expect = 0.019
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 2/131 (1%)
Frame = +2
Query: 62 LALLSVSDKTGLLSLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSG 241
LA+L+VSDK + LA L G ++A+ GT + G
Sbjct: 2 LAVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRV 61
Query: 242 ENFTSAVHAGILARLSDSDQEDMKRQKYEMISVVVCNLY--PFVQTVSKXDVTVADAVEN 415
+ T ++ GILAR +D+ +++R + +V CN Y P Q + E
Sbjct: 62 KTLTVSLMGGILARDEPADRAEVERHGLTRVHLVCCNYYRLPDPQPAQPFE----RFREL 117
Query: 416 IDIGGVTLLRA 448
ID+GG +LRA
Sbjct: 118 IDVGGPAMLRA 128
Score = 38.3 bits (85), Expect = 0.24
Identities = 18/30 (60%), Positives = 22/30 (73%)
Frame = +3
Query: 162 RALRNAGLTVQDVSDITRAPEMLGGRVKTL 251
R LR+ G+TV VSD+ P +LGGRVKTL
Sbjct: 35 RLLRDHGVTVGAVSDLAGVPTLLGGRVKTL 64
>UniRef50_A4M1L4 Cluster: Putative uncharacterized protein; n=1;
Geobacter bemidjiensis Bem|Rep: Putative uncharacterized
protein - Geobacter bemidjiensis Bem
Length = 546
Score = 36.7 bits (81), Expect = 0.72
Identities = 18/36 (50%), Positives = 22/36 (61%)
Frame = -3
Query: 445 AQEGHAADVDVLDRVRXGHVXLRYRLDERVQVTDHH 338
A+ G AAD+DVLD + G V R ERV+V HH
Sbjct: 412 AEHGRAADIDVLDGILHGAVLFRDGRLERVEVYHHH 447
>UniRef50_A1HBX2 Cluster: Putative uncharacterized protein; n=2;
Ralstonia pickettii|Rep: Putative uncharacterized
protein - Ralstonia pickettii 12J
Length = 699
Score = 36.7 bits (81), Expect = 0.72
Identities = 22/36 (61%), Positives = 23/36 (63%)
Frame = -3
Query: 445 AQEGHAADVDVLDRVRXGHVXLRYRLDERVQVTDHH 338
AQ G AADVDVLD V L +RL ERVQV HH
Sbjct: 434 AQHGRAADVDVLDGVGQRAFVLGHRLLERVQV--HH 467
>UniRef50_Q2W3F3 Cluster: Suppressor protein SRP40; n=2;
Magnetospirillum|Rep: Suppressor protein SRP40 -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 281
Score = 35.1 bits (77), Expect = 2.2
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +2
Query: 101 SLAKSLSECGLQLIASGGTATGASERXPDSSRCVGHHESTGDARGSGENFTSAVHAGILA 280
S+ K+L E Q+ SG + G S++ PD+S +S GD + + + F S H
Sbjct: 80 SVIKALDEFESQIQQSG--SAGGSQKGPDASELFSKLDSDGDGKLTQDEFVSGRH----- 132
Query: 281 RLSDSDQEDMKRQKYEMIS 337
D+ ED +Q Y+ I+
Sbjct: 133 ---DNVSEDQAKQLYQKIA 148
>UniRef50_Q9VV43 Cluster: TPPP family protein CG4893; n=8;
Endopterygota|Rep: TPPP family protein CG4893 -
Drosophila melanogaster (Fruit fly)
Length = 192
Score = 35.1 bits (77), Expect = 2.2
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Frame = +2
Query: 71 LSVSDKTGLLSLAKSLSECGLQLIAS--GGTATGASERXPDSSRCVGHHESTGDARGSGE 244
L+ + K L + + L+ CG + S G A A +R D+S+ G H+ DA G G+
Sbjct: 105 LAKTKKVELSEIKQKLASCGAPGVVSVSAGKAAAAVDRLTDTSKYTGSHKERFDASGKGK 164
>UniRef50_Q8XQP2 Cluster: Probable hemagglutinin/hemolysin-related
protein; n=2; Proteobacteria|Rep: Probable
hemagglutinin/hemolysin-related protein - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 4106
Score = 34.7 bits (76), Expect = 2.9
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Frame = -1
Query: 504 SIVVGRVTDDGDPV---VVLGXARRRVTPPMSMFSTASATVTSXLDTVWTNGYRLQTTTL 334
S VV VTDD DPV +V G + TP ++ + A +T+ TV+ NG + T T
Sbjct: 257 SPVVASVTDDVDPVTGAIVSGSSTNDATPTLAGTAEAGSTI-----TVYDNGTAIGTATA 311
Query: 333 IISYF*RFMSSWSESDNRAKIPACTADVKFSPDPRASPV 217
S F + + +D I D + P S +
Sbjct: 312 DASGNWTFTPATALADGSHSITVTATDAAGNVSPATSAI 350
>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
vinifera|Rep: DNA-directed RNA polymerase - Vitis
vinifera (Grape)
Length = 153
Score = 34.3 bits (75), Expect = 3.8
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 1/52 (1%)
Frame = +2
Query: 260 VHAGILARLSDSDQ-EDMKRQKYEMISVVVCNLYPFVQTVSKXDVTVADAVE 412
+H GILAR E + VVV NLYPF VS + D +E
Sbjct: 13 IHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPFYDKVSLGGIEFEDEIE 64
>UniRef50_A7AVV8 Cluster: Kinesin, putative; n=1; Babesia bovis|Rep:
Kinesin, putative - Babesia bovis
Length = 618
Score = 34.3 bits (75), Expect = 3.8
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +2
Query: 524 EQTSSDVFRAQGRDLALKAFTHTSGL*LAHIRTTSGKQYS 643
E T DV+ A RDL KAF +G A+ T++GK Y+
Sbjct: 286 EATQEDVYNATSRDLVQKAFDGINGTVFAYGCTSAGKTYT 325
>UniRef50_Q54ZP8 Cluster: Putative homeobox transcription factor;
n=2; Dictyostelium discoideum AX4|Rep: Putative homeobox
transcription factor - Dictyostelium discoideum AX4
Length = 516
Score = 33.9 bits (74), Expect = 5.1
Identities = 29/113 (25%), Positives = 51/113 (45%)
Frame = +2
Query: 140 IASGGTATGASERXPDSSRCVGHHESTGDARGSGENFTSAVHAGILARLSDSDQEDMKRQ 319
I GG G+S SSR + S+G + GSG N +S+++ I SD+D + +R+
Sbjct: 32 IGGGGGGGGSSSSRSSSSRSSSNRSSSGSSGGSGSNSSSSINNII---NSDNDFK-TERK 87
Query: 320 KYEMISVVVCNLYPFVQTVSKXDVTVADAVENIDIGGVTLLRAXPRTTTGSPS 478
+ + + + N+ T + T +N +I + R GSP+
Sbjct: 88 QTKSPPLTLPNIKTTTTTTTTTTTTTTTTTKNENISSSESENSSSR--VGSPN 138
>UniRef50_Q4TDB5 Cluster: Chromosome undetermined SCAF6370, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF6370,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 166
Score = 33.1 bits (72), Expect = 8.9
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Frame = -2
Query: 173 PKRP-WRYRHWRSTAGHIPTDSLLTRVDPFCPK 78
P+RP W R WRST +P L T + P+ P+
Sbjct: 73 PRRPSWPIRRWRSTGACLPCSCLHTPLPPWSPR 105
>UniRef50_Q2LEU6 Cluster: PRL2-6; n=1; Streptomyces sp. 44414|Rep:
PRL2-6 - Streptomyces sp. 44414
Length = 173
Score = 33.1 bits (72), Expect = 8.9
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = -1
Query: 150 PLAINCRPHSDRLFANESRPVLSETLRRASFPFDAMFCLLKHYCVSCRI 4
PL+ + DRLF SRPVL+ RRA P DA + + CR+
Sbjct: 9 PLSADSAERLDRLFRLYSRPVLALAARRAKRPEDADDIAAETWLKVCRV 57
>UniRef50_Q7PUV5 Cluster: ENSANGP00000017516; n=2; Coelomata|Rep:
ENSANGP00000017516 - Anopheles gambiae str. PEST
Length = 920
Score = 33.1 bits (72), Expect = 8.9
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +2
Query: 146 SGGTATGASERXPDSSRCVGHHESTGD--ARGSGENFTSAVHAGILARLSDSDQEDMKRQ 319
S GT TG++ R D+S HH+S D ++G G +A + A+ S S E +K++
Sbjct: 649 SSGT-TGSNSRTADTSEKYHHHKSKKDKSSKGQGGQGATAATPPVEAKDSSSASEPVKKR 707
Query: 320 K 322
K
Sbjct: 708 K 708
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 725,076,059
Number of Sequences: 1657284
Number of extensions: 14106530
Number of successful extensions: 37763
Number of sequences better than 10.0: 60
Number of HSP's better than 10.0 without gapping: 36151
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37666
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 72963732758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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