BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fbpv0091 (776 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase wit... 204 3e-51 UniRef50_UPI0000DB7966 Cluster: PREDICTED: similar to ADAM metal... 112 8e-24 UniRef50_UPI0000D554CF Cluster: PREDICTED: similar to ADAM metal... 111 1e-23 UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38; Euteleostomi... 81 4e-14 UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome sh... 72 2e-11 UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep... 72 2e-11 UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20; Euteleostomi|... 66 7e-10 UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease ... 63 7e-09 UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32; Euteleostomi... 63 7e-09 UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM metal... 62 2e-08 UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM metal... 61 3e-08 UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-... 61 3e-08 UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whol... 61 3e-08 UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64; Euteleostomi... 61 3e-08 UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice ... 59 1e-07 UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona intesti... 58 2e-07 UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome sh... 57 6e-07 UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome sh... 56 7e-07 UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella ve... 56 1e-06 UniRef50_A7RW19 Cluster: Predicted protein; n=1; Nematostella ve... 56 1e-06 UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome sh... 55 2e-06 UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|R... 55 2e-06 UniRef50_Q9UKP5 Cluster: ADAMTS-6 precursor; n=5; Tetrapoda|Rep:... 55 2e-06 UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep... 55 2e-06 UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23; Euteleostomi... 55 2e-06 UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6 va... 54 3e-06 UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-)... 54 4e-06 UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31; Euteleostomi|... 54 4e-06 UniRef50_UPI0000E46B78 Cluster: PREDICTED: similar to ADAM metal... 53 7e-06 UniRef50_Q14F51 Cluster: COMPase; n=15; Euteleostomi|Rep: COMPas... 53 7e-06 UniRef50_Q9UKP4 Cluster: ADAMTS-7 precursor; n=23; Euteleostomi|... 53 7e-06 UniRef50_UPI000069E320 Cluster: ADAM metallopeptidase with throm... 52 1e-05 UniRef50_UPI00004CFC4D Cluster: ADAM metallopeptidase with throm... 52 1e-05 UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella ve... 52 1e-05 UniRef50_A2RRN9 Cluster: ADAMTS12 protein; n=5; Eumetazoa|Rep: A... 52 2e-05 UniRef50_P58397 Cluster: ADAMTS-12 precursor; n=23; Euteleostomi... 52 2e-05 UniRef50_UPI0000D56749 Cluster: PREDICTED: similar to CG3622-PB,... 52 2e-05 UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Re... 52 2e-05 UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19; Euteleostomi... 52 2e-05 UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9 p... 51 3e-05 UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2; ... 51 4e-05 UniRef50_UPI0000DA2EEE Cluster: PREDICTED: similar to ADAMTS-8 p... 50 5e-05 UniRef50_Q4SHJ1 Cluster: Chromosome 5 SCAF14581, whole genome sh... 50 5e-05 UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA;... 50 6e-05 UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n... 50 9e-05 UniRef50_Q19791 Cluster: ADAMTS family gon-1 precursor; n=3; cel... 50 9e-05 UniRef50_Q9P2N4 Cluster: ADAMTS-9 precursor; n=50; Euteleostomi|... 50 9e-05 UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep: ... 50 9e-05 UniRef50_UPI0000D5652D Cluster: PREDICTED: similar to ADAM metal... 49 1e-04 UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep:... 49 1e-04 UniRef50_UPI00015B5B5C Cluster: PREDICTED: similar to adamts-7; ... 49 1e-04 UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome s... 49 1e-04 UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADA... 49 1e-04 UniRef50_Q3ULV2 Cluster: Mammary gland RCB-0527 Jyg-MC(B) cDNA, ... 49 1e-04 UniRef50_UPI00015B5FBF Cluster: PREDICTED: similar to a disinteg... 48 2e-04 UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13; ... 48 2e-04 UniRef50_UPI0000DB737E Cluster: PREDICTED: similar to ADAMTS-9 p... 48 2e-04 UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1 p... 48 2e-04 UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep:... 48 2e-04 UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella ve... 48 2e-04 UniRef50_A7S1V9 Cluster: Predicted protein; n=1; Nematostella ve... 48 2e-04 UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-... 48 3e-04 UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B ... 48 3e-04 UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamt... 48 3e-04 UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04 UniRef50_UPI0000D9BA61 Cluster: PREDICTED: similar to a disinteg... 47 5e-04 UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella ve... 47 6e-04 UniRef50_Q9W493 Cluster: CG4096-PA; n=3; Sophophora|Rep: CG4096-... 46 8e-04 UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella ve... 46 8e-04 UniRef50_Q9W1Z6 Cluster: CG3622-PB, isoform B; n=5; Sophophora|R... 46 0.001 UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p... 46 0.001 UniRef50_A7SQN1 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.001 UniRef50_Q9R160 Cluster: ADAM 24 precursor; n=9; Murinae|Rep: AD... 46 0.001 UniRef50_Q01AC1 Cluster: Meltrins, fertilins and related Zn-depe... 45 0.002 UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Re... 45 0.002 UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleavi... 45 0.002 UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-... 45 0.002 UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1; Rh... 45 0.002 UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas monolakensi... 45 0.002 UniRef50_A7SIV0 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.002 UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whol... 44 0.003 UniRef50_Q9W1J9 Cluster: CG9850-PA, isoform A; n=6; Endopterygot... 44 0.003 UniRef50_Q8MT72 Cluster: LP02257p; n=1; Drosophila melanogaster|... 44 0.003 UniRef50_Q293F2 Cluster: GA22072-PA; n=1; Drosophila pseudoobscu... 44 0.003 UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona intesti... 44 0.003 UniRef50_Q09JL6 Cluster: Metalloprotease; n=1; Argas monolakensi... 44 0.006 UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von Wil... 43 0.010 UniRef50_A1IIV7 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 43 0.010 UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.017 UniRef50_UPI00015B5990 Cluster: PREDICTED: similar to metallopro... 41 0.030 UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12 ... 41 0.030 UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7; ... 41 0.040 UniRef50_Q4RE58 Cluster: Chromosome 2 SCAF15135, whole genome sh... 41 0.040 UniRef50_Q13443 Cluster: ADAM 9 precursor; n=35; Euteleostomi|Re... 41 0.040 UniRef50_UPI00015B59D4 Cluster: PREDICTED: similar to metallopro... 40 0.052 UniRef50_UPI0000E8086C Cluster: PREDICTED: similar to metallopro... 40 0.052 UniRef50_UPI0000E25573 Cluster: PREDICTED: ADAM metallopeptidase... 40 0.052 UniRef50_Q9BZ11 Cluster: ADAM 33 precursor; n=29; Tetrapoda|Rep:... 40 0.052 UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to metallopro... 40 0.069 UniRef50_Q7Z1F9 Cluster: Salivary gland metalloprotease; n=4; Ix... 40 0.069 UniRef50_Q5Y973 Cluster: Metalloprotease; n=1; Melittobia digita... 40 0.069 UniRef50_A7SM44 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.069 UniRef50_Q4SXN1 Cluster: Chromosome 12 SCAF12356, whole genome s... 40 0.092 UniRef50_A6NNH1 Cluster: Uncharacterized protein ENSP00000351782... 40 0.092 UniRef50_Q13444 Cluster: ADAM 15 precursor; n=51; Theria|Rep: AD... 40 0.092 UniRef50_UPI0000F1F309 Cluster: PREDICTED: hypothetical protein;... 39 0.12 UniRef50_A7SM43 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.12 UniRef50_Q20930 Cluster: ADAM family mig-17 precursor; n=2; Caen... 39 0.12 UniRef50_P83512 Cluster: Hemorrhagic metalloproteinase BaP1; n=5... 39 0.12 UniRef50_UPI0000F2C9F5 Cluster: PREDICTED: similar to fertilin a... 39 0.16 UniRef50_Q58EW5 Cluster: LOC733175 protein; n=1; Xenopus laevis|... 39 0.16 UniRef50_Q8MYA8 Cluster: ADT-1; n=2; Caenorhabditis|Rep: ADT-1 -... 39 0.16 UniRef50_Q45R50 Cluster: Salivary gland metalloprotease; n=1; Rh... 39 0.16 UniRef50_UPI0000F2B1C1 Cluster: PREDICTED: similar to ADAM metal... 38 0.28 UniRef50_UPI00005A473E Cluster: PREDICTED: similar to a disinteg... 38 0.28 UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome s... 38 0.28 UniRef50_O12960 Cluster: ADAM 13; n=3; Xenopus|Rep: ADAM 13 - Xe... 38 0.28 UniRef50_UPI0000F1E743 Cluster: PREDICTED: similar to ADAM13; n=... 38 0.37 UniRef50_Q4SEB0 Cluster: Chromosome 2 SCAF14623, whole genome sh... 38 0.37 UniRef50_Q4RSP7 Cluster: Chromosome 12 SCAF14999, whole genome s... 38 0.37 UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5; Caenorhabdit... 38 0.37 UniRef50_O43184 Cluster: ADAM 12 precursor; n=44; Euteleostomi|R... 38 0.37 UniRef50_Q11RV7 Cluster: Putative uncharacterized protein; n=1; ... 37 0.49 UniRef50_Q2YHM3 Cluster: S-adenosine decarboxylase; n=2; lamiids... 37 0.49 UniRef50_Q2PGH5 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 37 0.49 UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella ve... 37 0.49 UniRef50_UPI0000683902 Cluster: FII; n=1; Deinagkistrodon acutus... 37 0.65 UniRef50_UPI000155622B Cluster: PREDICTED: similar to ADAM metal... 37 0.65 UniRef50_Q4RN96 Cluster: Chromosome 1 SCAF15015, whole genome sh... 37 0.65 UniRef50_Q45R47 Cluster: Salivary gland metalloprotease; n=1; Rh... 37 0.65 UniRef50_UPI00015B5D86 Cluster: PREDICTED: similar to CG9850-PA;... 36 0.85 UniRef50_UPI00015B5044 Cluster: PREDICTED: similar to metallopro... 36 0.85 UniRef50_UPI0000F2CA90 Cluster: PREDICTED: similar to fertilin a... 36 0.85 UniRef50_Q7ZYZ9 Cluster: A disintegrin and metalloproteinase dom... 36 0.85 UniRef50_Q868N4 Cluster: Putative metalloprotease; n=1; Ixodes s... 36 0.85 UniRef50_Q9R159 Cluster: ADAM 25 precursor; n=5; Mus musculus|Re... 36 0.85 UniRef50_A1IIA9 Cluster: Metalloprotease; n=1; Haemaphysalis lon... 36 1.1 UniRef50_Q9UKF5 Cluster: ADAM 29 precursor; n=13; Eutheria|Rep: ... 36 1.1 UniRef50_UPI0001556032 Cluster: PREDICTED: similar to arginine-f... 36 1.5 UniRef50_UPI000069F93B Cluster: UPI000069F93B related cluster; n... 36 1.5 UniRef50_A7SIU8 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.5 UniRef50_A6EZB8 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0 UniRef50_Q45R48 Cluster: Salivary gland metalloprotease; n=1; Rh... 35 2.0 UniRef50_Q19844 Cluster: Putative uncharacterized protein F27D9.... 35 2.0 UniRef50_UPI0000F1ED1E Cluster: PREDICTED: hypothetical protein;... 35 2.6 UniRef50_A5NVS4 Cluster: Secretion protein HlyD family protein; ... 35 2.6 UniRef50_A3K869 Cluster: Putative uncharacterized protein; n=1; ... 35 2.6 UniRef50_UPI00015B4562 Cluster: PREDICTED: similar to A disinteg... 34 3.4 UniRef50_UPI0000DB717B Cluster: PREDICTED: similar to ADAMTS-7 p... 34 3.4 UniRef50_Q09JE8 Cluster: Metalloprotease; n=2; Argasidae|Rep: Me... 34 3.4 UniRef50_Q2UTX6 Cluster: Predicted protein; n=1; Aspergillus ory... 34 3.4 UniRef50_UPI0000F2C3E0 Cluster: PREDICTED: hypothetical protein;... 34 4.6 UniRef50_Q76KT5 Cluster: Meltrin epsilon; n=3; Gallus gallus|Rep... 34 4.6 UniRef50_Q7SCK1 Cluster: Predicted protein; n=1; Neurospora cras... 34 4.6 UniRef50_Q90495 Cluster: Ecarin precursor; n=151; Colubroidea|Re... 34 4.6 UniRef50_Q9H013 Cluster: ADAM 19 precursor; n=34; Euteleostomi|R... 34 4.6 UniRef50_UPI00015B49E4 Cluster: PREDICTED: similar to A disinteg... 33 6.0 UniRef50_A6H8I8 Cluster: LOC100101326 protein; n=1; Xenopus laev... 33 6.0 UniRef50_Q7NFJ0 Cluster: Glr3535 protein; n=1; Gloeobacter viola... 33 6.0 UniRef50_Q3KBK8 Cluster: Leucine-rich repeat; n=1; Pseudomonas f... 33 6.0 UniRef50_A1IIB0 Cluster: Metalloprotease; n=2; Haemaphysalis lon... 33 6.0 UniRef50_Q8R534 Cluster: ADAM 1b precursor; n=36; Eutheria|Rep: ... 33 6.0 UniRef50_P78325 Cluster: ADAM 8 precursor; n=21; Eutheria|Rep: A... 33 6.0 UniRef50_UPI00015553DB Cluster: PREDICTED: similar to chemokine ... 33 8.0 UniRef50_UPI00005A5000 Cluster: PREDICTED: similar to a disinteg... 33 8.0 UniRef50_UPI0000510397 Cluster: COG1414: Transcriptional regulat... 33 8.0 UniRef50_Q4SW11 Cluster: Chromosome undetermined SCAF13694, whol... 33 8.0 UniRef50_Q7MTD8 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A7SIU7 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.0 UniRef50_Q2GV16 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 >UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase with thrombospondin motifs 1; n=1; Bombyx mori|Rep: A disintegrin and metalloproteinase with thrombospondin motifs 1 - Bombyx mori (Silk moth) Length = 1007 Score = 204 bits (497), Expect = 3e-51 Identities = 115/204 (56%), Positives = 125/204 (61%), Gaps = 5/204 (2%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181 +KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD Sbjct: 252 KKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 311 Query: 182 EGLTSAFVIAHELAHLLGLTHDGEAIVSLKRFEAL*WHRQYWLPYTTLPGQVVQRNNFMR 361 EGLTSAFVIAHELAHLLGLTHDGE + + F Sbjct: 312 EGLTSAFVIAHELAHLLGLTHDGEGNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHA 371 Query: 362 NQRSGGASMSVH*RGCGTRWC*GALKLCLHNG*TVQD*IRRRF---LSVSIRKVR--SAC 526 + +H R G K + T+ + R F SV R V+ SAC Sbjct: 372 KSKKW---WCLHERSTDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSV-CRSVKVRSAC 427 Query: 527 SRLWCAHRAMPHVCRFKASAASRG 598 SRLWCAHRAMPHVCR K + G Sbjct: 428 SRLWCAHRAMPHVCRSKRAPPLEG 451 Score = 145 bits (351), Expect = 1e-33 Identities = 75/117 (64%), Positives = 78/117 (66%), Gaps = 2/117 (1%) Frame = +3 Query: 396 TDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGS 575 TDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSV+ S Sbjct: 384 TDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSVKVRSACSRLWCAHRAMPHVCRS 443 Query: 576 KRAPPLEGTPCGQNQWCVDRVLRXDAWATVKETKG*KTKHTPEWG--EIWGGXEAHC 740 KRAPPLEGTPCGQNQWCVDRV + KETK + KHTPEWG E W A C Sbjct: 444 KRAPPLEGTPCGQNQWCVDRVCEPMPGHS-KETKV-ENKHTPEWGDWEEWSACNADC 498 Score = 108 bits (260), Expect = 1e-22 Identities = 46/47 (97%), Positives = 47/47 (100%) Frame = +1 Query: 256 NCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERT 396 NCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHER+ Sbjct: 337 NCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERS 383 >UniRef50_UPI0000DB7966 Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein; n=2; Apis mellifera|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein - Apis mellifera Length = 856 Score = 112 bits (270), Expect = 8e-24 Identities = 49/84 (58%), Positives = 63/84 (75%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181 ++SLE +NKWN + L D +WLTR +GGPSG+APV GVC +RS A++RD Sbjct: 343 KRSLENVNKWNRK---MLSSADVNHDVAVWLTRLDIGGPSGYAPVSGVCDPSRSCALNRD 399 Query: 182 EGLTSAFVIAHELAHLLGLTHDGE 253 EGLTSAF+IAHE+AH+LGLTHDG+ Sbjct: 400 EGLTSAFIIAHEVAHILGLTHDGD 423 Score = 63.3 bits (147), Expect = 7e-09 Identities = 24/42 (57%), Positives = 32/42 (76%) Frame = +1 Query: 259 CQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCL 384 C+ E RGSVMAP V AT H+F WS+CSK++FH + ++W CL Sbjct: 430 CKEEGSRGSVMAPMVAATFHHFYWSACSKKEFHRRVRRWSCL 471 Score = 51.6 bits (118), Expect = 2e-05 Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = +3 Query: 414 LGGAKELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAP 587 LG + FTMDEQCR EFGEG+ C++ + CG + + +C +K+ P Sbjct: 480 LGQLRTTVRETFTMDEQCRMEFGEGYEHCKTFDIEEPCSRLWCG-NSNISESCK-TKKGP 537 Query: 588 PLEGTPCGQNQ 620 PLEGT CG ++ Sbjct: 538 PLEGTLCGTSK 548 >UniRef50_UPI0000D554CF Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein; n=1; Tribolium castaneum|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein - Tribolium castaneum Length = 1061 Score = 111 bits (268), Expect = 1e-23 Identities = 49/84 (58%), Positives = 61/84 (72%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181 +KSLE N WN R L + D +WLTRS +GGPSG+APV G C RS A++RD Sbjct: 323 KKSLENANSWNSRLHASLAPDESHHDIAVWLTRSDIGGPSGYAPVAGACDPKRSCALNRD 382 Query: 182 EGLTSAFVIAHELAHLLGLTHDGE 253 EGLTSAF+IAHE+AH+LGL+HDG+ Sbjct: 383 EGLTSAFIIAHEMAHVLGLSHDGD 406 Score = 60.1 bits (139), Expect = 6e-08 Identities = 31/62 (50%), Positives = 39/62 (62%), Gaps = 2/62 (3%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQ 620 F+MDEQCR EFG+GFS+CR+ + CG A L C +K+ PLEGT CG N+ Sbjct: 474 FSMDEQCRMEFGDGFSLCRAFDIIEPCSHLWCGHERA-PLVCK-TKKGSPLEGTQCGFNK 531 Query: 621 WC 626 WC Sbjct: 532 WC 533 Score = 59.3 bits (137), Expect = 1e-07 Identities = 24/49 (48%), Positives = 32/49 (65%) Frame = +1 Query: 238 DPRWRSNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCL 384 D + ++C E+ +GSVMAP V AT H F WS CS+++F KKW CL Sbjct: 406 DKKHSNHCGDESAKGSVMAPLVAATFHQFFWSQCSRKEFKKIVKKWTCL 454 >UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38; Euteleostomi|Rep: ADAMTS-14 precursor - Homo sapiens (Human) Length = 1223 Score = 80.6 bits (190), Expect = 4e-14 Identities = 36/83 (43%), Positives = 54/83 (65%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDE 184 +SLE + +W + + P + D ++LTR G PSG+APV G+C RS A++ ++ Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFG-PSGYAPVTGMCHPLRSCALNHED 388 Query: 185 GLTSAFVIAHELAHLLGLTHDGE 253 G +SAFVIAHE H+LG+ HDG+ Sbjct: 389 GFSSAFVIAHETGHVLGMEHDGQ 411 Score = 49.6 bits (113), Expect = 9e-05 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602 EL ++MDEQCR +FG G+ C + R + C P C +K+ PPL+GT Sbjct: 470 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527 Query: 603 PCGQNQWC 626 C +WC Sbjct: 528 ECAPGKWC 535 Score = 42.7 bits (96), Expect = 0.010 Identities = 20/53 (37%), Positives = 24/53 (45%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411 + C E GSVMAP V A H F WS CSK + + CL + W Sbjct: 413 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 465 >UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF10257, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1125 Score = 71.7 bits (168), Expect = 2e-11 Identities = 33/85 (38%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178 +SLE + +W + + + D I+LTR + G G G+APV G+C RS ++ Sbjct: 108 QSLENVCRWAFLQQKQDTGDAEYHDHAIFLTRQEFGPTGMQGYAPVTGMCHPVRSCTLNH 167 Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253 ++G +SAFV+AHE H+LG+ HDG+ Sbjct: 168 EDGFSSAFVVAHETGHVLGMEHDGQ 192 Score = 41.9 bits (94), Expect = 0.017 Identities = 18/53 (33%), Positives = 24/53 (45%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411 + C E GS+MAP V A H F WS CS ++ + CL + W Sbjct: 194 NRCGDEVHMGSIMAPLVQAAFHRFHWSRCSMQELGRYLHSYDCLRDDPFDHNW 246 >UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep: ADAMTS-2 precursor - Homo sapiens (Human) Length = 1211 Score = 71.7 bits (168), Expect = 2e-11 Identities = 37/87 (42%), Positives = 55/87 (63%), Gaps = 4/87 (4%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPE-GSTGW-DATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAI 172 +SLE + +W Y L + P+ G + D I+LTR G G G+APV G+C RS + Sbjct: 337 QSLENVCRWAY--LQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTL 394 Query: 173 DRDEGLTSAFVIAHELAHLLGLTHDGE 253 + ++G +SAFV+AHE H+LG+ HDG+ Sbjct: 395 NHEDGFSSAFVVAHETGHVLGMEHDGQ 421 Score = 42.3 bits (95), Expect = 0.013 Identities = 18/53 (33%), Positives = 25/53 (47%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411 + C E GS+MAP V A H F WS CS+++ + CL + W Sbjct: 423 NRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDW 475 Score = 39.9 bits (89), Expect = 0.069 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602 +L ++M+EQCR +FG G+ +C + R + C P C +K+ PPL+GT Sbjct: 480 QLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 537 Query: 603 PCGQNQWC 626 C + C Sbjct: 538 MCAPGKHC 545 >UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20; Euteleostomi|Rep: ADAMTS-5 precursor - Homo sapiens (Human) Length = 930 Score = 66.5 bits (155), Expect = 7e-10 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172 +L+ KW ++H + +DA I TR L G G A VG +C+ RS A+ Sbjct: 337 TLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAV 396 Query: 173 DRDEGLTSAFVIAHELAHLLGLTHD 247 D+GL +AF +AHE+ HLLGL+HD Sbjct: 397 IEDDGLHAAFTVAHEIGHLLGLSHD 421 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/70 (32%), Positives = 35/70 (50%) Frame = +3 Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599 G +EL + +QC FG +SVC + R C V + C +K+ P +EG Sbjct: 482 GPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 539 Query: 600 TPCGQNQWCV 629 TPCG+ + C+ Sbjct: 540 TPCGKGRICL 549 >UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant; n=4; Euteleostomi|Rep: A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant - Homo sapiens (Human) Length = 847 Score = 63.3 bits (147), Expect = 7e-09 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 14/96 (14%) Frame = +2 Query: 5 KSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGG 142 KSL++ KW N+ H +PE G D + +TR + G G APVGG Sbjct: 63 KSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGG 122 Query: 143 VCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 +C + RS +++ D GL +AF IAHE+ H G+ HDG Sbjct: 123 MCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDG 158 >UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32; Euteleostomi|Rep: ADAMTS-10 precursor - Homo sapiens (Human) Length = 1103 Score = 63.3 bits (147), Expect = 7e-09 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 14/96 (14%) Frame = +2 Query: 5 KSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGG 142 KSL++ KW N+ H +PE G D + +TR + G G APVGG Sbjct: 309 KSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGG 368 Query: 143 VCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 +C + RS +++ D GL +AF IAHE+ H G+ HDG Sbjct: 369 MCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDG 404 >UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 16 preproprotein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 16 preproprotein - Strongylocentrotus purpuratus Length = 1202 Score = 61.7 bits (143), Expect = 2e-08 Identities = 28/62 (45%), Positives = 38/62 (61%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 TG D W +++ GFAP+GG+C+K RS I+ D GL AF +AHE H G+ HD Sbjct: 369 TGNDICSW--KNEPCDTLGFAPIGGMCSKYRSCTINEDTGLGLAFTVAHESGHSFGMVHD 426 Query: 248 GE 253 G+ Sbjct: 427 GD 428 Score = 36.7 bits (81), Expect = 0.65 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFG---LRAQGCGVPTALCLTCAGSKRAPPLEGT 602 L +++ D+QC+ +FG +C S G ++ C C T K P +GT Sbjct: 489 LPGELYSADQQCQWQFGPKARLC-SFNLGKSLCQSMWCHRGERRCET----KFLPAADGT 543 Query: 603 PCGQNQWCV 629 PCG WC+ Sbjct: 544 PCGATMWCI 552 >UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein - Strongylocentrotus purpuratus Length = 503 Score = 60.9 bits (141), Expect = 3e-08 Identities = 24/43 (55%), Positives = 34/43 (79%) Frame = +2 Query: 125 FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 +APV G+C TRS ++++DEGL S+FVIAHE H+ G+ HDG+ Sbjct: 119 YAPVTGMCAITRSCSLNKDEGLLSSFVIAHESGHVFGMEHDGQ 161 Score = 51.2 bits (117), Expect = 3e-05 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 3/79 (3%) Frame = +3 Query: 417 GGAKELSNYV---FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAP 587 GG E+ Y +TMDEQCR +FG G+ C + + +K+ P Sbjct: 213 GGYPEVRQYPGQRYTMDEQCRFDFGYGYRTCTAFDDYDKCDQLWCMHYRKRYVCRTKKGP 272 Query: 588 PLEGTPCGQNQWCVDRVLR 644 PL+GT CG WCV R Sbjct: 273 PLDGTECGPGMWCVQGTCR 291 Score = 46.4 bits (105), Expect = 8e-04 Identities = 16/44 (36%), Positives = 29/44 (65%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCL 384 + C+ +A RGS+MAP V++T ++ WS CS+ + +++CL Sbjct: 163 NTCEDDATRGSIMAPVVISTYIHYFWSKCSRGELQRYLSRYYCL 206 >UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).; n=2; Xenopus tropicalis|Rep: ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18). - Xenopus tropicalis Length = 812 Score = 60.9 bits (141), Expect = 3e-08 Identities = 29/62 (46%), Positives = 37/62 (59%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 TG D W +++ GFAP+ G+C+K RS I+ D GL AF IAHE H G+ HD Sbjct: 312 TGLDICSW--KNEPCDTLGFAPINGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 369 Query: 248 GE 253 GE Sbjct: 370 GE 371 >UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14706, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1151 Score = 60.9 bits (141), Expect = 3e-08 Identities = 29/62 (46%), Positives = 37/62 (59%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 TG D W +++ GFAP+ G+C+K RS I+ D GL AF IAHE H G+ HD Sbjct: 369 TGLDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 426 Query: 248 GE 253 GE Sbjct: 427 GE 428 Score = 34.3 bits (75), Expect = 3.4 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Frame = +3 Query: 399 DEGVELGGAK---ELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLT 563 DE ++G K +L ++ D QC+ +FG +C V+ ++ C C T Sbjct: 475 DEPKQIGQYKYPEKLPGQLYDADTQCKWQFGSKAKLCSLDFVKDICKSLWCHRAGHRCET 534 Query: 564 CAGSKRAPPLEGTPCGQNQWC 626 K P EGT CG + WC Sbjct: 535 ----KFMPAAEGTTCGPDMWC 551 >UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64; Euteleostomi|Rep: ADAMTS-16 precursor - Homo sapiens (Human) Length = 1224 Score = 60.9 bits (141), Expect = 3e-08 Identities = 29/62 (46%), Positives = 37/62 (59%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 TG D W +++ GFAP+ G+C+K RS I+ D GL AF IAHE H G+ HD Sbjct: 387 TGLDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 444 Query: 248 GE 253 GE Sbjct: 445 GE 446 >UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice Isoform A of ADAMTS-14 precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice Isoform A of ADAMTS-14 precursor - Takifugu rubripes Length = 1231 Score = 58.8 bits (136), Expect = 1e-07 Identities = 22/44 (50%), Positives = 33/44 (75%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G+APV G+C RS ++ ++G +SAFV+AHE H+LG+ HDG+ Sbjct: 472 GYAPVTGMCHPLRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQ 515 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/53 (33%), Positives = 26/53 (49%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411 + C E GS+MAP V A H + WS CSK++ + + CL + W Sbjct: 517 NRCADETSMGSIMAPLVQAAFHRYHWSRCSKQELNRYIHSYDCLLDDPFEHKW 569 Score = 34.3 bits (75), Expect = 3.4 Identities = 13/27 (48%), Positives = 19/27 (70%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSV 509 EL ++MDEQCR +FG G+ +C +V Sbjct: 574 ELPGINYSMDEQCRFDFGIGYKMCTAV 600 >UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 1030 Score = 58.0 bits (134), Expect = 2e-07 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGGVCTKTRSAA 169 + +L W RH +D I LTR+ L G + G A VG +C++ S A Sbjct: 326 QHTLREFCSWQKRHNTPDDSDPQHYDLAILLTRTNLCGDTCATLGLAEVGTMCSRRHSCA 385 Query: 170 IDRDEGLTSAFVIAHELAHLLGLTHD 247 + D+GL++++ IAHE+ H+L + HD Sbjct: 386 VIEDDGLSASYTIAHEVGHVLNMMHD 411 >UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 3 SCAF14978, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 981 Score = 56.8 bits (131), Expect = 6e-07 Identities = 23/42 (54%), Positives = 31/42 (73%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A VG +C+ RS A+ D+GL +AF +AHE+ HLLGL+HD Sbjct: 360 GMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHD 401 Score = 42.3 bits (95), Expect = 0.013 Identities = 23/70 (32%), Positives = 35/70 (50%) Frame = +3 Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599 G +EL + QCR FG ++VC + R C V + C +K+ P +EG Sbjct: 494 GPEELPGQSYDAVRQCRLAFGPEYTVCPGMDVCSRLW-CAVIRQGQMVCL-TKKLPAVEG 551 Query: 600 TPCGQNQWCV 629 TPCG+ + C+ Sbjct: 552 TPCGKGRICL 561 >UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14703, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 875 Score = 56.4 bits (130), Expect = 7e-07 Identities = 28/63 (44%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Frame = +2 Query: 74 WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 WD I TR L G S G A VG +C RS ++ D+GL SAF AHEL H+ + Sbjct: 270 WDTAILFTRQDLCGASTCDTLGMADVGTMCDSKRSCSVIEDDGLPSAFTTAHELGHVFNM 329 Query: 239 THD 247 HD Sbjct: 330 PHD 332 Score = 33.1 bits (72), Expect = 8.0 Identities = 18/60 (30%), Positives = 27/60 (45%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 + +D QC FGEG C ++ C + L C ++ P +GT CG +Q C Sbjct: 402 YGIDRQCELAFGEGSKPCPFIQPPCGRLWCTGKSNGHLVCM-TRHFPWADGTQCGNDQVC 460 >UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 834 Score = 56.0 bits (129), Expect = 1e-06 Identities = 22/47 (46%), Positives = 31/47 (65%) Frame = +2 Query: 113 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G G A V G+CT T+S ++ D GL+ A+ IAHE+ H G+ HDG+ Sbjct: 195 GTLGLAQVNGMCTSTKSCNVNEDSGLSVAYTIAHEIGHNFGMLHDGD 241 Score = 36.7 bits (81), Expect = 0.65 Identities = 19/65 (29%), Positives = 28/65 (43%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCG 611 L V+ D QCR ++G S C + + CG SK +GT CG Sbjct: 304 LPGTVYDADHQCRLQYGSNSSQCTGM-----SDPCGTLWCKVGKACQSKLEQAADGTYCG 358 Query: 612 QNQWC 626 +++WC Sbjct: 359 KDKWC 363 >UniRef50_A7RW19 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1592 Score = 55.6 bits (128), Expect = 1e-06 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 6/88 (6%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVGGVCTKTRSAA 169 SL + KW + E +D I LTR + +G A +G VC +RS + Sbjct: 81 SLRSFCKWQTKMNKPSDEEPGHFDTAILLTRKDICRAAGKCDTLGLAELGTVCNPSRSCS 140 Query: 170 IDRDEGLTSAFVIAHELAHLLGLTHDGE 253 I GL+SAF IAHELAH+ + HDG+ Sbjct: 141 IVEVTGLSSAFTIAHELAHVFNVPHDGD 168 >UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14536, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 670 Score = 55.2 bits (127), Expect = 2e-06 Identities = 32/70 (45%), Positives = 41/70 (58%), Gaps = 10/70 (14%) Frame = +2 Query: 77 DATIWLTRSQLGGPSG----------FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226 D TI+L+R + G PSG +APV G+C +S + D TSAFV AHE H Sbjct: 234 DHTIYLSRQEFG-PSGMQVRCFIPISYAPVTGMCQLHQSCVLVIDGRFTSAFVAAHETGH 292 Query: 227 LLGLTHDGEA 256 +LG+ HDGEA Sbjct: 293 VLGMEHDGEA 302 Score = 39.9 bits (89), Expect = 0.069 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSV-RFGLRAQGCGVPTALCLTCAGSKRAPPLEGTP 605 +L + ++MD+QC +FG G+S+C +V R + +K+ PPL+GT Sbjct: 360 QLPGFQYSMDQQCHFDFGPGYSLCTAVSRTHDPCKQLWCSDYHNPFYCKTKKGPPLDGTK 419 Query: 606 CGQNQWC 626 C + C Sbjct: 420 CAPGKHC 426 Score = 38.3 bits (85), Expect = 0.21 Identities = 16/53 (30%), Positives = 26/53 (49%) Frame = +1 Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411 ++C + GS+M+P V AT + + WS CS + H + CL + W Sbjct: 303 NSCADDVPLGSIMSPRVQATFYRYHWSRCSWMELHKYLHTYDCLRDDPFYYDW 355 >UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|Rep: ADAMTS6 variant 2 - Homo sapiens (Human) Length = 1117 Score = 55.2 bits (127), Expect = 2e-06 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 14/97 (14%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGST-------GWDATIWLTRSQLG-------GPSGFAPVG 139 +KSL++ KW L +G+T D + +TR + G G A V Sbjct: 319 DKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVA 378 Query: 140 GVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 G+C RS +I+ D GL SAF IAHE+ H G+ HDG Sbjct: 379 GMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDG 415 >UniRef50_Q9UKP5 Cluster: ADAMTS-6 precursor; n=5; Tetrapoda|Rep: ADAMTS-6 precursor - Homo sapiens (Human) Length = 860 Score = 55.2 bits (127), Expect = 2e-06 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 14/97 (14%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGST-------GWDATIWLTRSQLG-------GPSGFAPVG 139 +KSL++ KW L +G+T D + +TR + G G A V Sbjct: 319 DKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVA 378 Query: 140 GVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 G+C RS +I+ D GL SAF IAHE+ H G+ HDG Sbjct: 379 GMCEPERSCSINEDIGLGSAFTIAHEIVHNFGMNHDG 415 >UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep: ADAMTS-4 precursor - Homo sapiens (Human) Length = 837 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Frame = +2 Query: 74 WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 +D I TR L G S G A VG VC RS AI D+GL SAF AHEL H+ + Sbjct: 310 FDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNM 369 Query: 239 THD 247 HD Sbjct: 370 LHD 372 >UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23; Euteleostomi|Rep: ADAMTS-15 precursor - Homo sapiens (Human) Length = 950 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/63 (42%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Frame = +2 Query: 74 WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 WD I TR L G + G A VG +C RS ++ D+GL SAF AHEL H+ + Sbjct: 310 WDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNM 369 Query: 239 THD 247 HD Sbjct: 370 PHD 372 >UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6 variant 2, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS6 variant 2, partial - Strongylocentrotus purpuratus Length = 1320 Score = 54.4 bits (125), Expect = 3e-06 Identities = 23/47 (48%), Positives = 30/47 (63%) Frame = +2 Query: 113 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G G APVG +C +S I+ D GL +AF IAHE+ H G+ HDG+ Sbjct: 490 GTIGLAPVGVMCRPDQSCNINEDTGLATAFTIAHEIGHNFGMKHDGD 536 >UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).; n=1; Danio rerio|Rep: ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1). - Danio rerio Length = 886 Score = 54.0 bits (124), Expect = 4e-06 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172 +L + +W +H +D + TR L G G A VG C RS +I Sbjct: 276 TLRSFCQWQKQHNQPSDRHPEHYDTAVLFTRKDLCGAHSCDTLGMADVGTACDPDRSCSI 335 Query: 173 DRDEGLTSAFVIAHELAHLLGLTHD 247 D+GL +AF +AHEL H+ + HD Sbjct: 336 IEDDGLQAAFTVAHELGHVFNMPHD 360 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/66 (36%), Positives = 31/66 (46%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCG 611 L V+ D QCR FGE C + A C V +A L +K P +GTPCG Sbjct: 389 LPGSVYDADRQCRLTFGEESQHCPDLSSTCAALWCTVTSANGLLVCQTKNFPWADGTPCG 448 Query: 612 QNQWCV 629 N +C+ Sbjct: 449 SNSYCM 454 >UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31; Euteleostomi|Rep: ADAMTS-1 precursor - Homo sapiens (Human) Length = 967 Score = 54.0 bits (124), Expect = 4e-06 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Frame = +2 Query: 29 WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193 W +H + +D I TR L G G A VG VC +RS ++ D+GL Sbjct: 335 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 394 Query: 194 SAFVIAHELAHLLGLTHD 247 +AF AHEL H+ + HD Sbjct: 395 AAFTTAHELGHVFNMPHD 412 Score = 37.1 bits (82), Expect = 0.49 Identities = 18/68 (26%), Positives = 29/68 (42%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608 +L + + QC+ FGE C C + L C +K P +GT C Sbjct: 476 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 534 Query: 609 GQNQWCVD 632 G+ +WC++ Sbjct: 535 GEGKWCIN 542 >UniRef50_UPI0000E46B78 Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 3 proprotein - Strongylocentrotus purpuratus Length = 875 Score = 53.2 bits (122), Expect = 7e-06 Identities = 26/64 (40%), Positives = 42/64 (65%) Frame = +2 Query: 38 RHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHE 217 R ++K + +D +I++TR+ G P+G AP+G +C S ++ D+GL SAFV+AHE Sbjct: 203 RRIVKDDGSPSYFDHSIFMTRTHFG-PAGIAPLGLMCWIYFSCSLTEDDGLGSAFVLAHE 261 Query: 218 LAHL 229 L H+ Sbjct: 262 LGHV 265 Score = 39.5 bits (88), Expect = 0.092 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCR--SVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQ 620 +TMD+QC +FG+ + C V F + C P L + PP++G+ CG+N Sbjct: 290 YTMDQQCSFQFGKTYRKCHHTDVDFCMELY-CTSPD---LDGGCFMKGPPMDGSSCGENM 345 Query: 621 WCVDRV 638 CV V Sbjct: 346 ECVQEV 351 >UniRef50_Q14F51 Cluster: COMPase; n=15; Euteleostomi|Rep: COMPase - Homo sapiens (Human) Length = 1686 Score = 53.2 bits (122), Expect = 7e-06 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 + +L++ KW MK D I LTR L G + V G+C R Sbjct: 311 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 370 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S +I+ D GL AF +AHEL H G+ HDG Sbjct: 371 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 400 Score = 37.9 bits (84), Expect = 0.28 Identities = 19/62 (30%), Positives = 31/62 (50%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 ++ + QCR ++G + C + C V T TC SK ++GT CG+N+W Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGT----TCH-SKLDAAVDGTRCGENKW 521 Query: 624 CV 629 C+ Sbjct: 522 CL 523 >UniRef50_Q9UKP4 Cluster: ADAMTS-7 precursor; n=23; Euteleostomi|Rep: ADAMTS-7 precursor - Homo sapiens (Human) Length = 997 Score = 53.2 bits (122), Expect = 7e-06 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 + +L++ KW MK D I LTR L G + V G+C R Sbjct: 311 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 370 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S +I+ D GL AF +AHEL H G+ HDG Sbjct: 371 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 400 Score = 37.9 bits (84), Expect = 0.28 Identities = 19/62 (30%), Positives = 31/62 (50%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 ++ + QCR ++G + C + C V T TC SK ++GT CG+N+W Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGT----TCH-SKLDAAVDGTRCGENKW 521 Query: 624 CV 629 C+ Sbjct: 522 CL 523 >UniRef50_UPI000069E320 Cluster: ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein; n=1; Xenopus tropicalis|Rep: ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein - Xenopus tropicalis Length = 800 Score = 52.4 bits (120), Expect = 1e-05 Identities = 30/90 (33%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 + +L + KW MK E D + LTR + G + V G+C R Sbjct: 313 DNTLRSFCKWQKNLNMKGEEHPQHHDVAVLLTRKDICAAMNRPCETLGLSHVSGMCQPHR 372 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S I+ D GL +AF + HEL H G+ HDG Sbjct: 373 SCNINEDTGLPTAFTVTHELGHSFGVQHDG 402 >UniRef50_UPI00004CFC4D Cluster: ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein; n=2; Xenopus tropicalis|Rep: ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein - Xenopus tropicalis Length = 1551 Score = 52.4 bits (120), Expect = 1e-05 Identities = 30/90 (33%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 + +L + KW MK E D + LTR + G + V G+C R Sbjct: 277 DNTLRSFCKWQKNLNMKGEEHPQHHDVAVLLTRKDICAAMNRPCETLGLSHVSGMCQPHR 336 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S I+ D GL +AF + HEL H G+ HDG Sbjct: 337 SCNINEDTGLPTAFTVTHELGHSFGVQHDG 366 Score = 39.9 bits (89), Expect = 0.069 Identities = 20/61 (32%), Positives = 30/61 (49%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 ++ + QCR ++G S CR + C V + TC SK ++GT CG N+W Sbjct: 433 LYDVAHQCRLQYGSSSSFCRDIDNVCNTLWCSVGS----TCH-SKLDAAVDGTNCGHNKW 487 Query: 624 C 626 C Sbjct: 488 C 488 >UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 483 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 3/64 (4%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCL---TCAGSKRAPPLEGTPCGQN 617 F DEQCR +G+ + +C SV G CG T C+ +C ++ PP++GTPCG Sbjct: 251 FDGDEQCRIVYGQEYKLC-SVTTG----NCG--TLFCMRGSSCVNTRGMPPVDGTPCGHR 303 Query: 618 QWCV 629 +WC+ Sbjct: 304 KWCI 307 Score = 47.2 bits (107), Expect = 5e-04 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Frame = +2 Query: 11 LEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLG----GPSGFAPVGGVCTKTRSAAID 175 L +KW + PEGS +D + LTR G G A G C+ + A+++ Sbjct: 68 LHVFSKWF--QTVNTPEGSAEHFDNAVMLTRETCGINKCTLDGLAYFGSPCSSSLGASVN 125 Query: 176 RDEGLTSAFVIAHELAHLLGLTHD 247 GL +AF +AHE+AH G+ HD Sbjct: 126 DAYGLATAFSVAHEVAHNFGVDHD 149 >UniRef50_A2RRN9 Cluster: ADAMTS12 protein; n=5; Eumetazoa|Rep: ADAMTS12 protein - Homo sapiens (Human) Length = 1509 Score = 52.0 bits (119), Expect = 2e-05 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 7/91 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS---GFAPVGGVCTKTR 160 EK+L + KW K D + LTR + P G + + G+C R Sbjct: 315 EKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHR 374 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 S I+ D GL AF IAHEL H G+ HDG+ Sbjct: 375 SCNINEDSGLPLAFTIAHELGHSFGIQHDGK 405 Score = 34.3 bits (75), Expect = 3.4 Identities = 16/62 (25%), Positives = 29/62 (46%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 ++ + QC+ ++G + C+ V + C V C SK +GT CG+ +W Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVK-GFCR----SKLDAAADGTQCGEKKW 525 Query: 624 CV 629 C+ Sbjct: 526 CM 527 >UniRef50_P58397 Cluster: ADAMTS-12 precursor; n=23; Euteleostomi|Rep: ADAMTS-12 precursor - Homo sapiens (Human) Length = 1593 Score = 52.0 bits (119), Expect = 2e-05 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 7/91 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS---GFAPVGGVCTKTR 160 EK+L + KW K D + LTR + P G + + G+C R Sbjct: 315 EKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHR 374 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 S I+ D GL AF IAHEL H G+ HDG+ Sbjct: 375 SCNINEDSGLPLAFTIAHELGHSFGIQHDGK 405 Score = 34.3 bits (75), Expect = 3.4 Identities = 16/62 (25%), Positives = 29/62 (46%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 ++ + QC+ ++G + C+ V + C V C SK +GT CG+ +W Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVK-GFCR----SKLDAAADGTQCGEKKW 525 Query: 624 CV 629 C+ Sbjct: 526 CM 527 >UniRef50_UPI0000D56749 Cluster: PREDICTED: similar to CG3622-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3622-PB, isoform B - Tribolium castaneum Length = 942 Score = 51.6 bits (118), Expect = 2e-05 Identities = 20/43 (46%), Positives = 27/43 (62%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 G APV G+CT T S ++ S +V+AHE+ H LG+ HDG Sbjct: 330 GLAPVAGMCTTTSSCTVNEGRHFESVYVVAHEIGHNLGMRHDG 372 >UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Rep: ADAMTS-19 precursor - Homo sapiens (Human) Length = 1207 Score = 51.6 bits (118), Expect = 2e-05 Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 18/102 (17%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLP----EGSTGW-------DATIWLTRSQL----GGPS---GF 127 EK LE+ KW + K E ST W DA I +TR P G Sbjct: 394 EKMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPCDTVGI 453 Query: 128 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 A + G+C++ R I D GL AF IAHE+ H +G+ HD + Sbjct: 454 AYLSGMCSEKRKCIIAEDNGLNLAFTIAHEMGHNMGINHDND 495 Score = 36.7 bits (81), Expect = 0.65 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608 +L +T DEQC+ FG S C+ ++ + G C +K PP++GT C Sbjct: 557 KLPGMTYTADEQCQILFGPLASFCQEMQHVI-CTGLWCKVEGEKECR-TKLDPPMDGTDC 614 Query: 609 GQNQWC 626 +WC Sbjct: 615 DLGKWC 620 >UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19; Euteleostomi|Rep: ADAMTS-17 precursor - Homo sapiens (Human) Length = 1095 Score = 51.6 bits (118), Expect = 2e-05 Identities = 22/44 (50%), Positives = 27/44 (61%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +GGVC+ R + D GL AF IAHEL H LG+ HD + Sbjct: 359 GIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDD 402 Score = 40.3 bits (90), Expect = 0.052 Identities = 20/60 (33%), Positives = 32/60 (53%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 ++ +EQC+ FG + CR++ L G +C +K PPL+GT CG ++WC Sbjct: 470 YSANEQCQILFGMNATFCRNMEH-LMCAGLWCLVEGDTSCK-TKLDPPLDGTECGADKWC 527 >UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9); n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) - Strongylocentrotus purpuratus Length = 1693 Score = 51.2 bits (117), Expect = 3e-05 Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 6/64 (9%) Frame = +2 Query: 74 WDATIWLTRSQL--GGPS----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235 +D + LTR + GP G A +G VC RS +I D GL++AF +AHEL H+ Sbjct: 211 YDTAVLLTREDICRSGPDCDTLGLAELGTVCDPLRSCSIVEDNGLSAAFTMAHELGHVFN 270 Query: 236 LTHD 247 + HD Sbjct: 271 MLHD 274 Score = 41.9 bits (94), Expect = 0.017 Identities = 19/61 (31%), Positives = 30/61 (49%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623 V+ + +QC FG G ++C +R R G + C ++ P +GTPCG + W Sbjct: 342 VYNITQQCELVFGTGSTLCTYMRTCKRLWCTGYSRGVQTGCR-TQHMPWADGTPCGSHHW 400 Query: 624 C 626 C Sbjct: 401 C 401 >UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 872 Score = 50.8 bits (116), Expect = 4e-05 Identities = 22/54 (40%), Positives = 33/54 (61%) Frame = +2 Query: 92 LTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 L R+ + +G+APV G+C+ RS I+ S FV+ HE+ H LG+ HDG+ Sbjct: 248 LHRNGVKTVAGYAPVKGMCSGVRSCTINEGLDFGSVFVVTHEMGHSLGMYHDGD 301 >UniRef50_UPI0000DA2EEE Cluster: PREDICTED: similar to ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2); n=1; Rattus norvegicus|Rep: PREDICTED: similar to ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) - Rattus norvegicus Length = 905 Score = 50.4 bits (115), Expect = 5e-05 Identities = 19/42 (45%), Positives = 29/42 (69%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A VG +C +S ++ +DEGL +A+ +AHEL H+L + HD Sbjct: 348 GMADVGTICDPNKSCSVIKDEGLQAAYTLAHELGHVLSMPHD 389 >UniRef50_Q4SHJ1 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=3; root|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1689 Score = 50.4 bits (115), Expect = 5e-05 Identities = 30/90 (33%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 + SL + KW + K + D + LTR + G + V G+C R Sbjct: 300 DNSLLSFCKWQKKLNTKGDDHPLHHDVAVLLTRKDICAAVNVPCETLGLSHVAGMCQAHR 359 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S +I D GL AF +AHEL H G+ HDG Sbjct: 360 SCSISEDTGLPVAFTVAHELGHNFGIQHDG 389 Score = 35.1 bits (77), Expect = 2.0 Identities = 20/65 (30%), Positives = 31/65 (47%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCG 611 L +++ QCR ++G +C V C V T TC SK ++GT CG Sbjct: 452 LPGVLYSAVHQCRLQYGSRSRLCDDVDNVCSTLWCTVGT----TCH-SKLDGAVDGTSCG 506 Query: 612 QNQWC 626 +++WC Sbjct: 507 EDKWC 511 >UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG4096-PA - Apis mellifera Length = 1195 Score = 50.0 bits (114), Expect = 6e-05 Identities = 23/51 (45%), Positives = 29/51 (56%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEAIVSLKR 274 G A V G+C RS +++ D G+T A I HEL H G+ HD E I KR Sbjct: 393 GVAHVAGMCQPDRSCSVNEDNGITLAHTITHELGHNFGMYHDTEKIGCSKR 443 >UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n=5; Danio rerio|Rep: UPI00015A8026 UniRef100 entry - Danio rerio Length = 1504 Score = 49.6 bits (113), Expect = 9e-05 Identities = 21/44 (47%), Positives = 27/44 (61%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G + + G+C RS I+ D GL AF IAHEL H G+ HDG+ Sbjct: 381 GLSHLSGMCQPHRSCNINEDSGLPVAFTIAHELGHSFGIQHDGQ 424 Score = 36.7 bits (81), Expect = 0.65 Identities = 18/61 (29%), Positives = 29/61 (47%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 +T QC+ ++G + C V + C V + C SK P++GT CG +WC Sbjct: 491 YTPQHQCQLQYGPNATFCSEVENVCQILWCSVNGS----CR-SKLDSPIDGTRCGPEKWC 545 Query: 627 V 629 + Sbjct: 546 I 546 >UniRef50_Q19791 Cluster: ADAMTS family gon-1 precursor; n=3; cellular organisms|Rep: ADAMTS family gon-1 precursor - Caenorhabditis elegans Length = 2165 Score = 49.6 bits (113), Expect = 9e-05 Identities = 21/44 (47%), Positives = 28/44 (63%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +G +C +S AI D GL++AF IAHEL H+ + HD E Sbjct: 394 GLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHDDE 437 >UniRef50_Q9P2N4 Cluster: ADAMTS-9 precursor; n=50; Euteleostomi|Rep: ADAMTS-9 precursor - Homo sapiens (Human) Length = 1935 Score = 49.6 bits (113), Expect = 9e-05 Identities = 20/42 (47%), Positives = 27/42 (64%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A +G +C RS +I D GL++AF IAHEL H+ + HD Sbjct: 404 GLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHD 445 >UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep: ADAMTS-8 precursor - Homo sapiens (Human) Length = 890 Score = 49.6 bits (113), Expect = 9e-05 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 6/64 (9%) Frame = +2 Query: 74 WDATIWLTRSQLGGPSGF------APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235 +D I LTR G G A +G +C +S ++ DEGL +A +AHEL H+L Sbjct: 312 YDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLS 371 Query: 236 LTHD 247 + HD Sbjct: 372 MPHD 375 >UniRef50_UPI0000D5652D Cluster: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein; n=1; Tribolium castaneum|Rep: PREDICTED: similar to ADAM metallopeptidase with thrombospondin type 1 motif, 9 preproprotein - Tribolium castaneum Length = 1716 Score = 49.2 bits (112), Expect = 1e-04 Identities = 20/42 (47%), Positives = 29/42 (69%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A VG +C + S AI ++ GL+S++ IAHEL H+L + HD Sbjct: 411 GVAEVGSMCNPSSSCAIVKERGLSSSYTIAHELGHVLSMLHD 452 Score = 39.9 bits (89), Expect = 0.069 Identities = 21/60 (35%), Positives = 30/60 (50%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 F D+QC EFG G+ +C S + C T+ + S P +GT CG+N+WC Sbjct: 525 FEADKQCELEFGIGYKLC-SYQASCAVLWC---TSNDIYGCKSNLLPWADGTSCGRNRWC 580 >UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep: ENSANGP00000002429 - Anopheles gambiae str. PEST Length = 889 Score = 49.2 bits (112), Expect = 1e-04 Identities = 20/42 (47%), Positives = 27/42 (64%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G APV G+CT T S I+ + S FV++HE+ H LG+ HD Sbjct: 269 GLAPVAGMCTITSSCTINEGKHFESVFVVSHEIGHNLGMRHD 310 >UniRef50_UPI00015B5B5C Cluster: PREDICTED: similar to adamts-7; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to adamts-7 - Nasonia vitripennis Length = 1215 Score = 48.8 bits (111), Expect = 1e-04 Identities = 22/51 (43%), Positives = 29/51 (56%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEAIVSLKR 274 G A V G+C RS +++ D G+T A I HEL H G+ HD E I K+ Sbjct: 400 GVAHVAGMCQPDRSCSVNEDNGITLAHTITHELGHNFGMYHDTEKIGCSKK 450 >UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 11 SCAF14674, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2080 Score = 48.8 bits (111), Expect = 1e-04 Identities = 21/42 (50%), Positives = 27/42 (64%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A +G VC RS +I D GL++AF IAHEL H+ + HD Sbjct: 425 GLAELGTVCDPYRSCSIIEDNGLSTAFTIAHELGHVFNMPHD 466 >UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADAM metallopeptidase with thrombospondin type 1 motif, 8; n=9; Euteleostomi|Rep: Novel protein similar to vertebrate ADAM metallopeptidase with thrombospondin type 1 motif, 8 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 884 Score = 48.8 bits (111), Expect = 1e-04 Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Frame = +2 Query: 74 WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 +D I TR + G G A VG +C RS ++ D GL +AF ++HEL H+L + Sbjct: 309 YDTAILFTREDICGYKDCDTLGVADVGTMCDPKRSCSVIEDNGLQAAFTVSHELGHVLSM 368 Query: 239 THD 247 HD Sbjct: 369 PHD 371 Score = 39.9 bits (89), Expect = 0.069 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Frame = +3 Query: 423 AKELSNYVFTMDEQCRTEFGEGFSVCRS-------VRFGLRAQGCGVPTALCLTCAGSKR 581 A EL + F +D+QC+ FG ++ C + V+ R +G C T GS Sbjct: 432 AAELPGHTFGLDQQCQQAFGNKYTHCSNAPADQTCVQLWCREEG----KIQCTTRNGSLH 487 Query: 582 APPLEGTPCGQNQWCVDRVLRXDAWATVKETKG*KTKHTPEWGEIWGGXEAHC 740 +GTPCG+++ C + + A E K EWG WG C Sbjct: 488 W--ADGTPCGEDRRCREGLCLSSAMEEAGEQKVPVNGGWGEWGP-WGPCSRTC 537 >UniRef50_Q3ULV2 Cluster: Mammary gland RCB-0527 Jyg-MC(B) cDNA, RIKEN full-length enriched library, clone:G930037F13 product:a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20, full insert sequence; n=2; Murinae|Rep: Mammary gland RCB-0527 Jyg-MC(B) cDNA, RIKEN full-length enriched library, clone:G930037F13 product:a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20, full insert sequence - Mus musculus (Mouse) Length = 509 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 6/63 (9%) Frame = +2 Query: 77 DATIWLTRSQLGGPS------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 D + +TR + G G A +G +C +RS +I + GL++AF IAHEL H+ + Sbjct: 348 DTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNV 407 Query: 239 THD 247 HD Sbjct: 408 PHD 410 >UniRef50_UPI00015B5FBF Cluster: PREDICTED: similar to a disintegrin-like and metalloprotease with thrombospondin type 1 motifs 9B; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to a disintegrin-like and metalloprotease with thrombospondin type 1 motifs 9B - Nasonia vitripennis Length = 1733 Score = 48.4 bits (110), Expect = 2e-04 Identities = 20/44 (45%), Positives = 29/44 (65%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +G +C+ S AI +D GL +AF IAHE+ H+L + HD + Sbjct: 481 GLAELGRMCSPGSSCAIVQDNGLATAFTIAHEIGHVLNMPHDDD 524 >UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13; n=4; Gallus gallus|Rep: PREDICTED: similar to ADAMTS13 - Gallus gallus Length = 942 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 6/65 (9%) Frame = +2 Query: 77 DATIWLTRSQLGGPSG------FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 D +++TR L P G +GGVC+ + S I +D G IAHE+ H LG+ Sbjct: 116 DIVLYVTRFDLQLPDGNKELRGVTRLGGVCSSSWSCVITQDTGFDLGVTIAHEIGHSLGI 175 Query: 239 THDGE 253 HDGE Sbjct: 176 PHDGE 180 Score = 34.3 bits (75), Expect = 3.4 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Frame = +3 Query: 456 DEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 DEQC+ FG + C + + C V +C P L+GT CG N+WC Sbjct: 246 DEQCKIAFGSVATACTFADSNVDICKVLSCHVQPGDKSSCT-RLLVPLLDGTECGVNKWC 304 >UniRef50_UPI0000DB737E Cluster: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9); n=2; Apis mellifera|Rep: PREDICTED: similar to ADAMTS-9 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) - Apis mellifera Length = 1763 Score = 48.4 bits (110), Expect = 2e-04 Identities = 20/44 (45%), Positives = 29/44 (65%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +G +C+ S AI +D GL +AF IAHE+ H+L + HD + Sbjct: 368 GLAELGRMCSPRSSCAIVQDNGLAAAFTIAHEIGHVLDMPHDDD 411 Score = 34.3 bits (75), Expect = 3.4 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Frame = +3 Query: 399 DEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRS-VRFG----LRAQGCGVPTALCLT 563 D+ +E + L +++++QC FG G +C V G R C P Sbjct: 465 DKIMERTDPRRLPGEDYSVNKQCELVFGNGSRICNHMVGDGKSAVCRRLWCTTPNEDHYD 524 Query: 564 CAGSKRAPPLEGTPCGQNQWC 626 ++ P +GT CG+++WC Sbjct: 525 HCRTQHMPWADGTSCGRDKWC 545 >UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1 protein, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ADAMTS-1 protein, partial - Strongylocentrotus purpuratus Length = 734 Score = 48.4 bits (110), Expect = 2e-04 Identities = 20/52 (38%), Positives = 29/52 (55%) Frame = +2 Query: 95 TRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 T S + G G A + C ++R +I D GL + +AHE+ H LG+ HDG Sbjct: 368 TGSTVHGVLGLANMASACVRSRRCSIVEDNGLATGLTVAHEIGHALGIGHDG 419 >UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep: ENSANGP00000012879 - Anopheles gambiae str. PEST Length = 1325 Score = 48.4 bits (110), Expect = 2e-04 Identities = 21/44 (47%), Positives = 31/44 (70%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +G +C T + AI +D GL+++F IAHEL H+LG+ HD + Sbjct: 192 GLAELGTICRDT-ACAIVQDNGLSASFTIAHELGHVLGMPHDDD 234 >UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 259 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/44 (50%), Positives = 27/44 (61%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 +G A + G+C S I++D GL SAF IAHE H LG HDG Sbjct: 123 AGLASLKGMCNPDLSCTINQDMGLGSAFTIAHETGHNLGAKHDG 166 >UniRef50_A7S1V9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 502 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Frame = +2 Query: 74 WDATIWLTRSQL----GGPSGFAPVG---GVCTKTRSAAIDRDEGLTSAFVIAHELAHLL 232 +DA + +TR + P +G G+C R ++ D GL AF IAHELAH Sbjct: 85 YDAAVLMTRKDICADQNEPCSTVGIGYMYGMCDTKRRCSVSEDSGLNVAFTIAHELAHNF 144 Query: 233 GLTHDGE 253 G+ HDG+ Sbjct: 145 GVFHDGD 151 Score = 39.9 bits (89), Expect = 0.069 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLR-AQG--CGVP-TALCLTCAGSKRAPPLE 596 +L+ ++ D+QCR ++G C + R Q C + LC T KR PP Sbjct: 215 DLAGVTYSADDQCRLQYGNRAKHCDKMSECDRMCQNLWCAIRGEPLCRT----KRLPPAR 270 Query: 597 GTPCGQNQWCV 629 GT CG+ +WC+ Sbjct: 271 GTECGEGKWCM 281 >UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-15 precursor; n=2; Takifugu rubripes|Rep: Homolog of Homo sapiens "ADAMTS-15 precursor - Takifugu rubripes Length = 928 Score = 48.0 bits (109), Expect = 3e-04 Identities = 20/42 (47%), Positives = 26/42 (61%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A VG +C RS ++ D+GL SAF AHEL H+ + HD Sbjct: 306 GMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHD 347 >UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B - Mus musculus (Mouse) Length = 1641 Score = 48.0 bits (109), Expect = 3e-04 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160 E++L+ +W +K + D I LTR L G + V G+C Sbjct: 295 EETLKNFCRWQKNINIKGDDHPQHHDTAILLTRKDLCASMNQPCETLGLSHVSGLCHPQL 354 Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 S ++ D G+ AF +AHEL H G+ HDG Sbjct: 355 SCSVSEDTGMPLAFTVAHELGHSFGIQHDG 384 Score = 39.9 bits (89), Expect = 0.069 Identities = 20/66 (30%), Positives = 33/66 (50%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCG 611 L ++ ++ QCR ++G + C + C V T TC SK ++GT CG Sbjct: 448 LPGVLYDVNHQCRLQYGSHSAYCEDMDDVCHTLWCSVGT----TCH-SKLDAAVDGTSCG 502 Query: 612 QNQWCV 629 +N+WC+ Sbjct: 503 KNKWCL 508 >UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamts-7 - Aedes aegypti (Yellowfever mosquito) Length = 1037 Score = 47.6 bits (108), Expect = 3e-04 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A VGG+C +S +++ D G+T A I+HEL H G+ HD Sbjct: 423 GVANVGGMCRPDKSCSVNEDNGITLAHTISHELGHNFGMYHD 464 >UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 956 Score = 47.6 bits (108), Expect = 3e-04 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 7/88 (7%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTR-------SQLGGPSGFAPVGGVCTKTRSA 166 +LE+ KW R+ L +D TR +Q G A G+C+ SA Sbjct: 275 TLESFGKWAERNNNPLDNDENHYDYATLFTRYNICKDKNQPCDTLGLARTRGMCSFPSSA 334 Query: 167 AIDRDEGLTSAFVIAHELAHLLGLTHDG 250 ++++D GL +AHE H +G+ HDG Sbjct: 335 SVNQDNGLMLGMTLAHETGHSMGINHDG 362 Score = 35.9 bits (79), Expect = 1.1 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 5/104 (4%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRA---QGCGVP--TALCLTCAGSKRAPPLEGTPC 608 ++ D+QC+ +G+ C +F + C VP + C T + P +GT C Sbjct: 426 LYDKDQQCQLAYGQEAKFCSGAKFLDQVCVKLWCEVPAGSGQCKTA----QVPATDGTSC 481 Query: 609 GQNQWCVDRVLRXDAWATVKETKG*KTKHTPEWGEIWGGXEAHC 740 G+ +WC R A+ E G EW E + C Sbjct: 482 GEGKWC----KRGHCVASTSEGDGAMDGGWSEWSENYSRCSRSC 521 >UniRef50_UPI0000D9BA61 Cluster: PREDICTED: similar to a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; n=1; Macaca mulatta|Rep: PREDICTED: similar to a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 - Macaca mulatta Length = 359 Score = 47.2 bits (107), Expect = 5e-04 Identities = 19/43 (44%), Positives = 26/43 (60%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 G + V G+C S +I++D GL F +AHEL H G+ HDG Sbjct: 279 GLSHVAGICLPHCSCSINKDTGLPLGFTVAHELGHSFGIQHDG 321 >UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1664 Score = 46.8 bits (106), Expect = 6e-04 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Frame = +3 Query: 441 YVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLT---CAGSKRAPPLEGTPCG 611 Y F DEQCR +G + +CR R C + LC+ C + P++GTPCG Sbjct: 587 YTFDADEQCRLAYGLEYRLCRQQR-------CD--SLLCVKGSKCINPRNILPVDGTPCG 637 Query: 612 QNQWCVDRV 638 +WC+ + Sbjct: 638 NRKWCISGI 646 >UniRef50_Q9W493 Cluster: CG4096-PA; n=3; Sophophora|Rep: CG4096-PA - Drosophila melanogaster (Fruit fly) Length = 1059 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGGVCTKTRSAA 169 +K+L+ W ++ + D I +TR + + G A VGG+C +S + Sbjct: 399 QKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGGMCKPKQSCS 458 Query: 170 IDRDEGLTSAFVIAHELAHLLGLTHD 247 ++ D G+ + I HEL H G+ HD Sbjct: 459 VNEDNGIMLSHTITHELGHNFGMFHD 484 >UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 949 Score = 46.4 bits (105), Expect = 8e-04 Identities = 21/43 (48%), Positives = 29/43 (67%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 +G A G C SA+++ D+GL +AF IAHE+AH LG+ HD Sbjct: 351 NGLAFCGYSCESRYSASVNDDQGLQTAFSIAHEMAHNLGVDHD 393 Score = 36.3 bits (80), Expect = 0.85 Identities = 17/58 (29%), Positives = 29/58 (50%) Frame = +3 Query: 456 DEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWCV 629 DEQC +G G+ C + C + C+ ++ +PP++GT CG +WC+ Sbjct: 455 DEQCTMMYGRGYKRCPITQHQCDQMFCYRGNS-CV----ARGSPPVDGTACGWRKWCM 507 >UniRef50_Q9W1Z6 Cluster: CG3622-PB, isoform B; n=5; Sophophora|Rep: CG3622-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 1091 Score = 46.0 bits (104), Expect = 0.001 Identities = 20/46 (43%), Positives = 27/46 (58%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEAI 259 G A V G+CT S I+ + S FV+AHE+ H LG+ HD + I Sbjct: 412 GMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEI 457 >UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p - Drosophila melanogaster (Fruit fly) Length = 1688 Score = 45.6 bits (103), Expect = 0.001 Identities = 20/44 (45%), Positives = 30/44 (68%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253 G A +G VC+ + S +I +D GL +AF +AHEL H+L + HD + Sbjct: 561 GLAELGTVCSSS-SCSIVQDTGLPTAFTMAHELGHILNMNHDDD 603 Score = 38.3 bits (85), Expect = 0.21 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 1/70 (1%) Frame = +3 Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599 G + L ++++D QC+ FG F C + + C + S P +G Sbjct: 666 GTERLPGEIYSLDAQCQLSFGNDFGYCPTDE-ECKRLWCNRTSGNSNEQCASSNLPWADG 724 Query: 600 TPCGQN-QWC 626 TPCG + WC Sbjct: 725 TPCGSSGHWC 734 >UniRef50_A7SQN1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 800 Score = 45.6 bits (103), Expect = 0.001 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLGGPS----GFAPVGGVCTKTRSAA 169 K L +KW + P GS +D + LTR G S G A G C+ + A+ Sbjct: 296 KYLSVFSKWF--QTVNTPAGSVEHFDNAVMLTRDICGTNSCQLDGLAYFGYPCSTSLGAS 353 Query: 170 IDRDEGLTSAFVIAHELAHLLGLTHD 247 ++ G+++AF +AHE+AH G+ HD Sbjct: 354 VNDAHGVSAAFSVAHEVAHNFGVDHD 379 >UniRef50_Q9R160 Cluster: ADAM 24 precursor; n=9; Murinae|Rep: ADAM 24 precursor - Mus musculus (Mouse) Length = 761 Score = 45.6 bits (103), Expect = 0.001 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAID---RDEGLTSAFVIAHELAHLLGLTHDG 250 G A VG VC KT ID D+ LT ++AHE+ H LG++HDG Sbjct: 309 GIAYVGTVCDKTFGCGIDSIAEDDFLTIGHIVAHEIGHNLGMSHDG 354 >UniRef50_Q01AC1 Cluster: Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family; n=2; Ostreococcus tauri|Rep: Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family - Ostreococcus tauri Length = 872 Score = 45.2 bits (102), Expect = 0.002 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Frame = +2 Query: 11 LEAINKWNYRHLMKLPEGSTGWDATIWLTRS--QLGGPSGFAPVGGVCT--KTRSAAIDR 178 L A W+ R L + WD+ I + Q G G A VG VCT + A+ + Sbjct: 136 LNAAQAWSERRPAVL---NFDWDSVIITAKRNPQFSGAIGMAGVGTVCTLRSVSTNAVTK 192 Query: 179 DEGLTSAFVIAHELAHLLGLTHDGEA 256 L + IAHE H LG HDG+A Sbjct: 193 GAYLYAGSTIAHEFGHTLGFMHDGDA 218 >UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Rep: ADAMTS-13 precursor - Homo sapiens (Human) Length = 1427 Score = 45.2 bits (102), Expect = 0.002 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Frame = +2 Query: 77 DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 D +++TR L P G V GG C+ T S I D G IAHE+ H GL Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232 Query: 239 THDG 250 HDG Sbjct: 233 EHDG 236 Score = 33.9 bits (74), Expect = 4.6 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617 ++ +EQCR FG C R L +A C +C+ P L+GT CG Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363 Query: 618 QWC 626 +WC Sbjct: 364 KWC 366 >UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleaving protease Adamts-13; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to VWF-cleaving protease Adamts-13 - Strongylocentrotus purpuratus Length = 1216 Score = 44.8 bits (101), Expect = 0.002 Identities = 16/42 (38%), Positives = 26/42 (61%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A + G C+ T +++ D G +S +IAHE+ H +G+ HD Sbjct: 420 GIANLRGACSATHQCSVNEDNGPSSGLIIAHEIGHTVGMLHD 461 >UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).; n=1; Xenopus tropicalis|Rep: ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP). - Xenopus tropicalis Length = 763 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGW--DATIWLTRSQLGGPSGFAPV------GGVCTKTRS 163 SL ++ KW+ H + P+ S D +++TR L P G V GG C+ S Sbjct: 78 SLISLCKWS--HKVNPPDDSDPQHADLVLYVTRFDLELPDGNKQVRGVTQLGGACSSVWS 135 Query: 164 AAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 I D G +AHE+ H G+ HDG Sbjct: 136 CVITEDTGFDLGVTMAHEIGHSFGINHDG 164 >UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 492 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEG-LTSAFVIAHELAHLLGLTH 244 TG + W + G+A VGG CT R + G +V AHELAH LG H Sbjct: 283 TGMSMSAWENGALQHWVGGYAYVGGACTAWRVGMSEERVGSYYGVYVYAHELAHSLGCAH 342 Query: 245 DGE 253 DG+ Sbjct: 343 DGD 345 >UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 293 Score = 44.8 bits (101), Expect = 0.002 Identities = 19/47 (40%), Positives = 30/47 (63%), Gaps = 1/47 (2%) Frame = +2 Query: 113 GPSGFAPVGGVCTKTRSAAIDRDEGLTSA-FVIAHELAHLLGLTHDG 250 G +G+ +GGVC + ++ A + + G S ++ AHE+AH LG HDG Sbjct: 38 GTAGYTMLGGVCNEYKTGAAEDEAGSYSGVYITAHEIAHGLGAVHDG 84 >UniRef50_A7SIV0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 772 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/80 (33%), Positives = 40/80 (50%) Frame = +2 Query: 11 LEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGL 190 L A+ KW +L + D + + S + G G A G +C+ + D GL Sbjct: 49 LSALGKWASTNLPTDDSNAAHPDVIVLI--SSISG--GLAGAGSICSGL-GKTVSGDIGL 103 Query: 191 TSAFVIAHELAHLLGLTHDG 250 +A +IAHE+AH LG+ HDG Sbjct: 104 QTAVIIAHEVAHALGVGHDG 123 Score = 41.5 bits (93), Expect = 0.023 Identities = 19/67 (28%), Positives = 33/67 (49%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608 +L +++ ++QC+ ++G + C + C A C S APPL+GT C Sbjct: 204 KLPGHIYDRNKQCQMQYGSTYRQCEPKLSDCGSLFCTENGATC----PSNVAPPLDGTYC 259 Query: 609 GQNQWCV 629 G +WC+ Sbjct: 260 GLRKWCI 266 >UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1518 Score = 44.4 bits (100), Expect = 0.003 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVGGVCTKTRSAA 169 SL ++ +W + D +++TR L P G A +GG C+ S Sbjct: 135 SLRSVCEWGRKINPSNDSDPLHADLLLYITRYDLVLPDGNKQVRGVAQLGGACSSEWSCV 194 Query: 170 IDRDEGLTSAFVIAHELAHLLGLTHDG 250 I D G IAHE+ H G+ HDG Sbjct: 195 IAEDTGFDLGITIAHEIGHSFGINHDG 221 >UniRef50_Q9W1J9 Cluster: CG9850-PA, isoform A; n=6; Endopterygota|Rep: CG9850-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 639 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Frame = +2 Query: 113 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHDG 250 G +GFA VGG C K S AI D G S ++A HE+ HLLG HDG Sbjct: 434 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDG 486 >UniRef50_Q8MT72 Cluster: LP02257p; n=1; Drosophila melanogaster|Rep: LP02257p - Drosophila melanogaster (Fruit fly) Length = 476 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Frame = +2 Query: 113 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHDG 250 G +GFA VGG C K S AI D G S ++A HE+ HLLG HDG Sbjct: 13 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDG 65 >UniRef50_Q293F2 Cluster: GA22072-PA; n=1; Drosophila pseudoobscura|Rep: GA22072-PA - Drosophila pseudoobscura (Fruit fly) Length = 561 Score = 44.4 bits (100), Expect = 0.003 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Frame = +2 Query: 113 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHDG 250 G +GFA VGG C K S AI D G S ++A HE+ HLLG HDG Sbjct: 205 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDG 257 >UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona intestinalis|Rep: Zinc finger protein - Ciona intestinalis (Transparent sea squirt) Length = 1820 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/42 (42%), Positives = 26/42 (61%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A +G +C +S +I+ D GL++AF IAHE+ H HD Sbjct: 448 GLAELGTMCDLRKSCSINEDNGLSTAFTIAHEIGHEFNAPHD 489 >UniRef50_Q09JL6 Cluster: Metalloprotease; n=1; Argas monolakensis|Rep: Metalloprotease - Argas monolakensis Length = 273 Score = 43.6 bits (98), Expect = 0.006 Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 2/48 (4%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSAAIDRDEGLT--SAFVIAHELAHLLGLTHDGEA 256 +GFA +G VCT R I D T VIAHE+AHLLG HDG++ Sbjct: 78 AGFAYIGAVCTDAR-VGIGEDIPKTWFGVRVIAHEVAHLLGCPHDGDS 124 >UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von Willebrand factor-cleaving protease precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Von Willebrand factor-cleaving protease precursor - Takifugu rubripes Length = 1328 Score = 42.7 bits (96), Expect = 0.010 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 6/64 (9%) Frame = +2 Query: 77 DATIWLTRSQLGGPSG------FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 D +++TR L P G A +GG C+ S I D G I HE+ H G+ Sbjct: 107 DLLLYITRYDLVLPDGNNQVRGVAQLGGACSSEWSCVITEDTGFDLGITITHEIGHSFGI 166 Query: 239 THDG 250 HDG Sbjct: 167 NHDG 170 Score = 33.9 bits (74), Expect = 4.6 Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 3/64 (4%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617 + +D+QCR FG C L R C V +C P L+GT C + Sbjct: 234 YGVDDQCRIAFGSAARACSFTNSDLVTCRTLSCHVNPGDDSSCK-RLLVPLLDGTECAPH 292 Query: 618 QWCV 629 +WC+ Sbjct: 293 RWCL 296 >UniRef50_A1IIV7 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 397 Score = 42.7 bits (96), Expect = 0.010 Identities = 21/48 (43%), Positives = 29/48 (60%), Gaps = 2/48 (4%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLT--SAFVIAHELAHLLGLTHDGEAI 259 GFA VG VCT+ R + D+ +T ++AHE+ H LG +HDG I Sbjct: 286 GFAFVGSVCTRNR-VGLGEDKPMTYIGIRIMAHEMGHTLGCSHDGSGI 332 >UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 980 Score = 41.9 bits (94), Expect = 0.017 Identities = 18/67 (26%), Positives = 34/67 (50%) Frame = +3 Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608 +L ++ ++QC+ ++G ++ C + + C + TC + AP L+GT C Sbjct: 362 KLPGQIYDRNKQCQMQYGSAYTECAQKKSSCDSLFCSSDGS---TCPSTVLAP-LDGTSC 417 Query: 609 GQNQWCV 629 G QWC+ Sbjct: 418 GDRQWCI 424 Score = 35.5 bits (78), Expect = 1.5 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 1/114 (0%) Frame = +2 Query: 11 LEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGL 190 + A+ W ++ S D + +T + G A G VC+ T + D G+ Sbjct: 271 IAALGTWMGTNIPSEDSNSAHADVVVLVTNTV----GGLAEAGSVCSSTGRVLVG-DTGI 325 Query: 191 TSAFVIAHELAHLLGL-THDGEAIVSLKRFEAL*WHRQYWLPYTTLPGQVVQRN 349 +A +AHE+AH L T +A ++ + + WH + LPGQ+ RN Sbjct: 326 QTASAMAHEIAHAGDLCTELDDAPGNIVHYPSS-WHDK-------LPGQIYDRN 371 >UniRef50_UPI00015B5990 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 386 Score = 41.1 bits (92), Expect = 0.030 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHLLGLTH 244 T +D+ +T S G + +G +C + S A D+ + A HEL HLL L H Sbjct: 268 TNYDSAFVMTASNTKTVQGQSHLGSICNRQYSTAFVEDDASFGGLLTATHELGHLLNLPH 327 Query: 245 DG 250 DG Sbjct: 328 DG 329 >UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12); n=2; Apis mellifera|Rep: PREDICTED: similar to ADAMTS-12 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12) - Apis mellifera Length = 1076 Score = 41.1 bits (92), Expect = 0.030 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 G A + C + ++AAI D GL +AHE+ H++G +HD Sbjct: 358 GLAYLATACDRKKAAAICEDTGLNLGITVAHEVGHVMGCSHD 399 >UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to adamts-7 - Nasonia vitripennis Length = 1782 Score = 40.7 bits (91), Expect = 0.040 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 6/94 (6%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVGGVCTKTRS 163 EK+LE+ KW + + +D +TR + G A V C + ++ Sbjct: 324 EKTLESFAKWIEKLNPTDTQHPNHFDIGALVTRHDICAEGNNCNLLGLAFVAAACERKKA 383 Query: 164 AAIDRDEGLTSAFVIAHELAHLLGLTHDGEAIVS 265 A I+ D GL VIAHE+ H GL GE +++ Sbjct: 384 ACINEDSGLLLGIVIAHEIGHTSGL---GECLIN 414 Score = 35.5 bits (78), Expect = 1.5 Identities = 11/21 (52%), Positives = 16/21 (76%) Frame = +3 Query: 573 SKRAPPLEGTPCGQNQWCVDR 635 SK APP +GT C +N+WC+ + Sbjct: 473 SKGAPPADGTKCAENKWCIHK 493 >UniRef50_Q4RE58 Cluster: Chromosome 2 SCAF15135, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2 SCAF15135, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 647 Score = 40.7 bits (91), Expect = 0.040 Identities = 23/51 (45%), Positives = 30/51 (58%), Gaps = 3/51 (5%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAID--RDEGLTS-AFVIAHELAHLLGLTHDGE 253 GG G A VG VC+ + S I+ D L + V+AHE+ H LG+THD E Sbjct: 200 GGVLGMAFVGTVCSASTSGGINVFSDNSLPYFSTVVAHEMGHNLGMTHDDE 250 >UniRef50_Q13443 Cluster: ADAM 9 precursor; n=35; Euteleostomi|Rep: ADAM 9 precursor - Homo sapiens (Human) Length = 819 Score = 40.7 bits (91), Expect = 0.040 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = +2 Query: 77 DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247 D+ + + GG +G A VG VC+++ + I+ +T A ++AHEL H LG+ HD Sbjct: 299 DSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHD 358 >UniRef50_UPI00015B59D4 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 428 Score = 40.3 bits (90), Expect = 0.052 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Frame = +2 Query: 74 WDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHDG 250 +D+TI LT G +G A +G +C + D+ A HEL HLL L HDG Sbjct: 310 YDSTITLTNLNTGPIAGSAYIGKICDDGYNVGFINDDASYGGIQAATHELGHLLNLPHDG 369 >UniRef50_UPI0000E8086C Cluster: PREDICTED: similar to metalloprotease-disintegrin; n=1; Gallus gallus|Rep: PREDICTED: similar to metalloprotease-disintegrin - Gallus gallus Length = 775 Score = 40.3 bits (90), Expect = 0.052 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Frame = +2 Query: 29 WNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI---DRDEGLTSA 199 W + L+K + + + R G G A VG VC++ + +I + + L A Sbjct: 259 WRQKDLLKRSRNDV---SHLIIGRGSYNGSIGMAFVGTVCSQVQGGSISTLNHNNVLRHA 315 Query: 200 FVIAHELAHLLGLTHD 247 V+AHEL H LG+ HD Sbjct: 316 TVVAHELGHNLGMKHD 331 >UniRef50_UPI0000E25573 Cluster: PREDICTED: ADAM metallopeptidase domain 33; n=1; Pan troglodytes|Rep: PREDICTED: ADAM metallopeptidase domain 33 - Pan troglodytes Length = 622 Score = 40.3 bits (90), Expect = 0.052 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Frame = +2 Query: 98 RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 R+ G G APV G+C S + D + +A +AHE+ H LGL+HD Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356 >UniRef50_Q9BZ11 Cluster: ADAM 33 precursor; n=29; Tetrapoda|Rep: ADAM 33 precursor - Homo sapiens (Human) Length = 813 Score = 40.3 bits (90), Expect = 0.052 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Frame = +2 Query: 98 RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 R+ G G APV G+C S + D + +A +AHE+ H LGL+HD Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356 >UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 334 Score = 39.9 bits (89), Expect = 0.069 Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Frame = +2 Query: 74 WDATIWLTRSQLGGPSGF-------APVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHL 229 +DA I +T ++ GF A +GG+C++ + AI D G +IA HEL HL Sbjct: 211 YDAAILMTGLKMNLIEGFFEISGLAAKLGGICSRQYNVAIVTDSGAYRNTLIAIHELGHL 270 Query: 230 LGLTHD 247 L L+HD Sbjct: 271 LNLSHD 276 >UniRef50_Q7Z1F9 Cluster: Salivary gland metalloprotease; n=4; Ixodes|Rep: Salivary gland metalloprotease - Ixodes scapularis (Black-legged tick) (Deer tick) Length = 488 Score = 39.9 bits (89), Expect = 0.069 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI-DRDEGLTSAFVIAHELAHLLGLTH 244 TG + + W+ G+A +G C++ R D A+V AHELAH LG H Sbjct: 282 TGKNMSEWVDGKLQHWVGGYAYLGTACSEWRVGMCEDPPTSYYGAYVFAHELAHNLGCQH 341 Query: 245 DGE 253 DG+ Sbjct: 342 DGD 344 >UniRef50_Q5Y973 Cluster: Metalloprotease; n=1; Melittobia digitata|Rep: Metalloprotease - Melittobia digitata Length = 392 Score = 39.9 bits (89), Expect = 0.069 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Frame = +2 Query: 74 WDATIWLTRSQLGGPSG-FAPVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHD 247 +DAT +++S G +G +C + S A +D G + A HEL HLL L HD Sbjct: 275 YDATFIMSQSSAKTIKGAIVQLGSICNRQNSIAFVQDNGSYEGLLSATHELGHLLNLPHD 334 Query: 248 G 250 G Sbjct: 335 G 335 >UniRef50_A7SM44 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1022 Score = 39.9 bits (89), Expect = 0.069 Identities = 20/53 (37%), Positives = 30/53 (56%) Frame = +2 Query: 92 LTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 +TRS GG A G C A+ + G+ ++ ++AHE+AH LG+ HDG Sbjct: 274 VTRSVTGG---LASAGSTCGSL-GKALAGNSGIQASIIVAHEIAHTLGVGHDG 322 Score = 35.1 bits (77), Expect = 2.0 Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Frame = +3 Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALC---LTCAGSKRAPPLEGTPCGQ 614 ++ +QC+ + + C G + CG+ +TC S APPL+GT CG Sbjct: 391 IYDRTKQCQMTYNSDYKGC-----GPKIGDCGLLYCSKNGGVTCL-SMNAPPLDGTHCGV 444 Query: 615 NQWCV 629 +WC+ Sbjct: 445 RKWCI 449 >UniRef50_Q4SXN1 Cluster: Chromosome 12 SCAF12356, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12 SCAF12356, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 795 Score = 39.5 bits (88), Expect = 0.092 Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Frame = +2 Query: 98 RSQLGGPSGFAPVGGVCTKTRSAAIDR--DEGLTS-AFVIAHELAHLLGLTHD 247 + GG +G A V VC+++ S I+ + L + A ++AHEL H LG+ HD Sbjct: 353 KKSFGGTAGMAFVSTVCSRSHSGGINAFPNNNLPAFASIVAHELGHNLGMNHD 405 >UniRef50_A6NNH1 Cluster: Uncharacterized protein ENSP00000351782; n=24; Eutheria|Rep: Uncharacterized protein ENSP00000351782 - Homo sapiens (Human) Length = 645 Score = 39.5 bits (88), Expect = 0.092 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 3/96 (3%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAA---IDR 178 ++E W Y +L D ++ T ++LG +A G+CT A I R Sbjct: 239 AVELFGVWKYHNLYS----EISHDTSVVFTSNRLGNSECYASFDGICTPNWGAMFVYIMR 294 Query: 179 DEGLTSAFVIAHELAHLLGLTHDGEAIVSLKRFEAL 286 A V AH L H +GL HD +R L Sbjct: 295 YHLFRGACVTAHALGHNMGLRHDSVGCYCFRRTNCL 330 >UniRef50_Q13444 Cluster: ADAM 15 precursor; n=51; Theria|Rep: ADAM 15 precursor - Homo sapiens (Human) Length = 814 Score = 39.5 bits (88), Expect = 0.092 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Frame = +2 Query: 8 SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181 +LE W HL+ +LP D+ +T + GP+ G A +C+ S ++ D Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334 Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247 L A IAHEL H LGL HD Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359 >UniRef50_UPI0000F1F309 Cluster: PREDICTED: hypothetical protein; n=8; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 800 Score = 39.1 bits (87), Expect = 0.12 Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Frame = +2 Query: 80 ATIWLTRSQLGGPSGFAPVGGVCTKTRSAAID--RDEGLTS-AFVIAHELAHLLGLTHD 247 A + + S GG G A VG VC+ + S AI D L + V AHEL H LG++HD Sbjct: 292 AQLVVPSSYPGGVLGMAFVGSVCSASTSGAISVFSDNNLQYYSTVAAHELGHNLGMSHD 350 >UniRef50_A7SM43 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1136 Score = 39.1 bits (87), Expect = 0.12 Identities = 17/47 (36%), Positives = 23/47 (48%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 G G A CT ++ GL +A +I HE+ H LG+ HDG Sbjct: 367 GTRGGLAQAASTCTTQFGRTVNSYVGLGTALLITHEIGHTLGVRHDG 413 >UniRef50_Q20930 Cluster: ADAM family mig-17 precursor; n=2; Caenorhabditis|Rep: ADAM family mig-17 precursor - Caenorhabditis elegans Length = 509 Score = 39.1 bits (87), Expect = 0.12 Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRD--EGLTSAFVIAHELAHLLGLTHDG 250 G A VG +C S+++ D GLTS ++AHE+ H LG HDG Sbjct: 271 GMAYVGNICENGDSSSVVEDIGAGLTS-LIMAHEIGHSLGALHDG 314 >UniRef50_P83512 Cluster: Hemorrhagic metalloproteinase BaP1; n=5; Viperidae|Rep: Hemorrhagic metalloproteinase BaP1 - Bothrops asper (Terciopelo) Length = 203 Score = 39.1 bits (87), Expect = 0.12 Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181 K+L++ +W R L LP S D LT G + G A GG+C S + RD Sbjct: 74 KTLKSFGEWRERDL--LPRISH--DHAQLLTAVVFDGNTIGRAYTGGMCDPRHSVGVVRD 129 Query: 182 EGLTSAFV---IAHELAHLLGLTHD 247 + +V +AHEL H LG+ HD Sbjct: 130 HSKNNLWVAVTMAHELGHNLGIXHD 154 >UniRef50_UPI0000F2C9F5 Cluster: PREDICTED: similar to fertilin alpha-II; n=1; Monodelphis domestica|Rep: PREDICTED: similar to fertilin alpha-II - Monodelphis domestica Length = 753 Score = 38.7 bits (86), Expect = 0.16 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Frame = +2 Query: 14 EAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAID---RDE 184 E + +N +LP+ +T + +T +G G A VG VC A ++ +++ Sbjct: 284 ETLYDFNQWQASELPKRAT-YSVAHLITGQDVGSHQGHAFVGTVCASRNLAGVEVFHQED 342 Query: 185 GLTSAFVIAHELAHLLGLTHD 247 A ++AHEL H LG+ HD Sbjct: 343 IPRFAALLAHELGHNLGMKHD 363 >UniRef50_Q58EW5 Cluster: LOC733175 protein; n=1; Xenopus laevis|Rep: LOC733175 protein - Xenopus laevis (African clawed frog) Length = 658 Score = 38.7 bits (86), Expect = 0.16 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 4/63 (6%) Frame = +2 Query: 77 DATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRDEGLTSAFV---IAHELAHLLGLTH 244 D ++T + G + G A VG +C+ T S + +D S + +AHE+ H LG+ H Sbjct: 313 DNAQFITNTDFDGATVGLAYVGTLCSSTLSTGVIQDHSQQSISIGATVAHEMGHNLGMNH 372 Query: 245 DGE 253 D E Sbjct: 373 DEE 375 >UniRef50_Q8MYA8 Cluster: ADT-1; n=2; Caenorhabditis|Rep: ADT-1 - Caenorhabditis elegans Length = 1461 Score = 38.7 bits (86), Expect = 0.16 Identities = 16/44 (36%), Positives = 26/44 (59%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250 +G APV +C + ++ L +FV+AHE+ H +G+ HDG Sbjct: 357 AGVAPVARMCDPLFACSLVEGLHLGRSFVLAHEMGHNMGMVHDG 400 >UniRef50_Q45R50 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 493 Score = 38.7 bits (86), Expect = 0.16 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAF-VIAHELAHLLGLTHDGEA 256 G A V GVCT+ A + + G + HE+AHLLG HDG+A Sbjct: 300 GLAFVAGVCTELFVAIGEDNAGSYDGMHALTHEVAHLLGAAHDGDA 345 >UniRef50_UPI0000F2B1C1 Cluster: PREDICTED: similar to ADAM metallopeptidase domain 20 preproprotein; n=1; Monodelphis domestica|Rep: PREDICTED: similar to ADAM metallopeptidase domain 20 preproprotein - Monodelphis domestica Length = 735 Score = 37.9 bits (84), Expect = 0.28 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Frame = +2 Query: 77 DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAID---RDEGLTSAFVIAHELAHLLGLTHD 247 D T R G + VG +C SA ID D L + +AH L H LG+ HD Sbjct: 292 DVTRLFVRYNFGIEKSLSYVGTICNNVTSAGIDAYVEDNLLEFSITVAHGLGHNLGMLHD 351 Query: 248 GEAIVSLKR 274 ++ + ++ Sbjct: 352 YDSCICAQK 360 >UniRef50_UPI00005A473E Cluster: PREDICTED: similar to a disintegrin and metalloproteinase domain 20 preproprotein; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to a disintegrin and metalloproteinase domain 20 preproprotein - Canis familiaris Length = 732 Score = 37.9 bits (84), Expect = 0.28 Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 3/50 (6%) Frame = +2 Query: 113 GPSGFAPVGGVCTKTRSAAIDR---DEGLTSAFVIAHELAHLLGLTHDGE 253 G G + VG +C + A+D D AFV++HEL H LG+ HD E Sbjct: 312 GILGISYVGSICNYNTNCAVDAFTSDNLGFFAFVVSHELGHSLGMWHDEE 361 >UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF14974, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 901 Score = 37.9 bits (84), Expect = 0.28 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Frame = +2 Query: 74 WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 +D + TR + G G A VG +C RS ++ D GL AF AHEL G Sbjct: 281 YDTAVLFTREDICGQKSCDTLGVADVGTMCDPKRSCSVIEDNGLQDAFTAAHELGE-YGR 339 Query: 239 THDGEAIVSL 268 D +S+ Sbjct: 340 AEDASGGISV 349 Score = 35.1 bits (77), Expect = 2.0 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Frame = +3 Query: 432 LSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQ--GCGVP-TALCLTCAGSKRAPPLEGT 602 L +++D+QC+ FGE F C + G C T C T GS P +GT Sbjct: 450 LPGAAYSLDQQCQQVFGEEFLHCPNASDGAACSQLWCREDGTLQCSTRNGS--LPWADGT 507 Query: 603 PCGQNQWCV 629 PCG + C+ Sbjct: 508 PCGPDGTCL 516 >UniRef50_O12960 Cluster: ADAM 13; n=3; Xenopus|Rep: ADAM 13 - Xenopus laevis (African clawed frog) Length = 914 Score = 37.9 bits (84), Expect = 0.28 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G G AP+ G+CT S + D + +A +AHE+ H G++HD Sbjct: 303 GTTIGMAPLEGMCTAENSGGVSMDHSENAIGAAATMAHEIGHNFGMSHD 351 >UniRef50_UPI0000F1E743 Cluster: PREDICTED: similar to ADAM13; n=3; Danio rerio|Rep: PREDICTED: similar to ADAM13 - Danio rerio Length = 1041 Score = 37.5 bits (83), Expect = 0.37 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHDGE 253 G G AP+ G+C+ S I+ D + +A +AHE+ H G++HD E Sbjct: 409 GTTIGMAPLEGMCSHENSGGINVDHSELPIGAAATMAHEIGHNFGMSHDHE 459 >UniRef50_Q4SEB0 Cluster: Chromosome 2 SCAF14623, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2 SCAF14623, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 524 Score = 37.5 bits (83), Expect = 0.37 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G G AP+ +CT +S I D L +A +AHEL H G+ HD Sbjct: 110 GTTIGMAPIMSMCTAEQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 158 >UniRef50_Q4RSP7 Cluster: Chromosome 12 SCAF14999, whole genome shotgun sequence; n=5; Eukaryota|Rep: Chromosome 12 SCAF14999, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1673 Score = 37.5 bits (83), Expect = 0.37 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226 G + + G+C RS I+ D GL AF +AHE+ H Sbjct: 381 GLSHLSGMCQPHRSCNINEDSGLPVAFTVAHEMGH 415 Score = 36.7 bits (81), Expect = 0.65 Identities = 18/61 (29%), Positives = 29/61 (47%) Frame = +3 Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626 +T QC+ ++G + C V + C V + C SK P++GT CG +WC Sbjct: 566 YTTHHQCQLQYGSNATFCNEVDNVCQILWCSVNGS----CR-SKLDSPIDGTRCGPEKWC 620 Query: 627 V 629 + Sbjct: 621 I 621 >UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5; Caenorhabditis|Rep: ADAMTS-like protease - Caenorhabditis elegans Length = 1020 Score = 37.5 bits (83), Expect = 0.37 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247 SG A + G+C + + TSAF+ HEL H +G+ HD Sbjct: 330 SGIARLDGMCDPWNTCTLAEGLDFTSAFIGTHELGHSVGMRHD 372 >UniRef50_O43184 Cluster: ADAM 12 precursor; n=44; Euteleostomi|Rep: ADAM 12 precursor - Homo sapiens (Human) Length = 909 Score = 37.5 bits (83), Expect = 0.37 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G G AP+ +CT +S I D L +A +AHEL H G+ HD Sbjct: 313 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 361 >UniRef50_Q11RV7 Cluster: Putative uncharacterized protein; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Putative uncharacterized protein - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 266 Score = 37.1 bits (82), Expect = 0.49 Identities = 17/40 (42%), Positives = 23/40 (57%) Frame = +2 Query: 125 FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTH 244 +A GG+ + R+ I +G SA V+AHEL H GL H Sbjct: 133 YAEGGGISSSVRAGQIVFKKGCFSAGVVAHELGHYFGLAH 172 >UniRef50_Q2YHM3 Cluster: S-adenosine decarboxylase; n=2; lamiids|Rep: S-adenosine decarboxylase - Plantago major (Common plantain) Length = 217 Score = 37.1 bits (82), Expect = 0.49 Identities = 22/58 (37%), Positives = 32/58 (55%) Frame = +3 Query: 405 GVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSK 578 G ELG + ++ E CR FG+G SV S F +R GCG PT++ + +GS+ Sbjct: 150 GKELGSVFNVGVKGYSCGELCRESFGDGSSVIYS-SF-IRTCGCGSPTSILHSWSGSE 205 >UniRef50_Q2PGH5 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 482 Score = 37.1 bits (82), Expect = 0.49 Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDR-DEGLTSAFVIAHELAHLLGLTHDGEAIVSL 268 G+ VGG C R + + A+++ HE+AH G HDG V+L Sbjct: 301 GYTYVGGACQDDRVGMCEELPKSYYGAYLMTHEIAHSFGCVHDGTEAVAL 350 >UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1006 Score = 37.1 bits (82), Expect = 0.49 Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 20/88 (22%) Frame = +3 Query: 426 KELSNYVFTMDEQCRTEFGEGFSVCRSV----------------RFGLRAQGCGVPTALC 557 + L +FT DEQCR +G F C + R+G+ AQ +C Sbjct: 389 RNLPGKLFTQDEQCRMAYGSAFKKCPATYSVRIICPVCTGYLPSRYGVFAQSSDCSHLMC 448 Query: 558 LTCAGSK----RAPPLEGTPCGQNQWCV 629 G+ P +GT CG WCV Sbjct: 449 SKDGGATCLRYHVPIPDGTRCGSRHWCV 476 >UniRef50_UPI0000683902 Cluster: FII; n=1; Deinagkistrodon acutus|Rep: FII - Deinagkistrodon acutus Length = 202 Score = 36.7 bits (81), Expect = 0.65 Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G G A VG +C SA I +D L A V+AHEL H LG+ HD Sbjct: 104 GAVVGLAFVGTMCNAKYSAGIIQDFSAIPLLMAVVMAHELGHNLGMLHD 152 >UniRef50_UPI000155622B Cluster: PREDICTED: similar to ADAM metallopeptidase domain 20 preproprotein, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to ADAM metallopeptidase domain 20 preproprotein, partial - Ornithorhynchus anatinus Length = 630 Score = 36.7 bits (81), Expect = 0.65 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Frame = +2 Query: 5 KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDR-- 178 K L N W HL LP S +D+ + G G A V +C ++A+ Sbjct: 84 KVLADFNAWQRTHL--LPRFS--YDSAHLIVNQPYGITLGLAYVKTICDNRYASAVQSFF 139 Query: 179 DEGLTS-AFVIAHELAHLLGLTHD 247 D L A V AHE H+ G+THD Sbjct: 140 DYRLLKLAVVFAHEQGHIFGMTHD 163 >UniRef50_Q4RN96 Cluster: Chromosome 1 SCAF15015, whole genome shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 1 SCAF15015, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 821 Score = 36.7 bits (81), Expect = 0.65 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEG 187 +L A W + L LP + A + R+ G G A + +C+ +S ++ D Sbjct: 295 TLAAFLSWRSKQLRALPNDN----AQLITGRAFQGTTIGLAQLKAMCSDYQSGGVNTDHS 350 Query: 188 LTS---AFVIAHELAHLLGLTHD 247 ++ A +AHE+ H G+THD Sbjct: 351 ESAVGVAATMAHEMGHNFGMTHD 373 >UniRef50_Q45R47 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 506 Score = 36.7 bits (81), Expect = 0.65 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Frame = +2 Query: 122 GFAPVGGVCTKTRSA-AIDRDEGLTSAFVIAHELAHLLGLTHDGEA 256 G+A VG C+K R D + HELAH LG +HDG A Sbjct: 303 GYAFVGSACSKNREQLGEDTAYSYRGIRTMTHELAHALGCSHDGTA 348 >UniRef50_UPI00015B5D86 Cluster: PREDICTED: similar to CG9850-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG9850-PA - Nasonia vitripennis Length = 386 Score = 36.3 bits (80), Expect = 0.85 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHLLGLTHDG 250 G + +G C + I D G ++A HE+AHLLG+ HDG Sbjct: 214 GLSLLGKACHSHLNTVIIEDNGGFGGIIVATHEIAHLLGVPHDG 257 >UniRef50_UPI00015B5044 Cluster: PREDICTED: similar to metalloprotease; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to metalloprotease - Nasonia vitripennis Length = 469 Score = 36.3 bits (80), Expect = 0.85 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Frame = +2 Query: 62 GSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAF-VIAHELAHLLGL 238 G +D TI +T S+ G A G +C K S A D G S AHEL HLL Sbjct: 340 GFRNYDGTILMTASKTRY-LGLAYKGEICNKPYSFAYISDFGDYSGVNTAAHELGHLLNF 398 Query: 239 THD 247 +HD Sbjct: 399 SHD 401 >UniRef50_UPI0000F2CA90 Cluster: PREDICTED: similar to fertilin alpha-I; n=1; Monodelphis domestica|Rep: PREDICTED: similar to fertilin alpha-I - Monodelphis domestica Length = 927 Score = 36.3 bits (80), Expect = 0.85 Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Frame = +2 Query: 104 QLGGPSGFAPVGGVCTKTRSAA---IDRDEGLTSAFVIAHELAHLLGLTHDGE 253 + G +G + +GG+C+ +++AA ++ A ++ HEL H +G+ HD + Sbjct: 378 ETGSKAGHSYLGGICSSSQAAAALAFPHEDVARFASLMTHELGHSMGMEHDSQ 430 >UniRef50_Q7ZYZ9 Cluster: A disintegrin and metalloproteinase domain 8; n=5; Clupeocephala|Rep: A disintegrin and metalloproteinase domain 8 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 843 Score = 36.3 bits (80), Expect = 0.85 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G G A + +C+ + S A++ D + A +AHE+ H LG++HD Sbjct: 295 GSTVGLATLYAMCSSSSSGAVNEDHNSNPIAVASTVAHEMGHNLGMSHD 343 >UniRef50_Q868N4 Cluster: Putative metalloprotease; n=1; Ixodes scapularis|Rep: Putative metalloprotease - Ixodes scapularis (Black-legged tick) (Deer tick) Length = 399 Score = 36.3 bits (80), Expect = 0.85 Identities = 22/57 (38%), Positives = 29/57 (50%) Frame = +2 Query: 92 LTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEAIV 262 L+ +GG SG+ V G T + G IAHELAH LG++H+GE V Sbjct: 285 LSGGNVGGCSGYCTVCGDNPITTNTMGFGRIGRWEPGTIAHELAHSLGMSHEGECPV 341 >UniRef50_Q9R159 Cluster: ADAM 25 precursor; n=5; Mus musculus|Rep: ADAM 25 precursor - Mus musculus (Mouse) Length = 760 Score = 36.3 bits (80), Expect = 0.85 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 3/48 (6%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAF---VIAHELAHLLGLTHDGEA 256 G A +G VC + + +DR G + +IAHE+ H LG+ HD + Sbjct: 322 GLAYIGSVCVPSHNCGVDRLLGGNLFYFGRIIAHEMGHNLGMEHDSSS 369 >UniRef50_A1IIA9 Cluster: Metalloprotease; n=1; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 483 Score = 35.9 bits (79), Expect = 1.1 Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Frame = +2 Query: 119 SGFAPVGGVCTKTRSA-AIDRDEGLTSAFVIAHELAHLLGLTHD 247 +G A VG VCTK A D + + +AHELAH LG HD Sbjct: 300 AGLAFVGTVCTKKGVAEGEDIAKSYMGVYCMAHELAHSLGAEHD 343 >UniRef50_Q9UKF5 Cluster: ADAM 29 precursor; n=13; Eutheria|Rep: ADAM 29 precursor - Homo sapiens (Human) Length = 820 Score = 35.9 bits (79), Expect = 1.1 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%) Frame = +2 Query: 77 DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244 D + T L G SG G+CT RS AI ++ G T + +AH L H LG+ H Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342 Query: 245 D 247 D Sbjct: 343 D 343 >UniRef50_UPI0001556032 Cluster: PREDICTED: similar to arginine-fifty homeobox; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to arginine-fifty homeobox - Ornithorhynchus anatinus Length = 462 Score = 35.5 bits (78), Expect = 1.5 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247 G G A V +C+ SAA+++D + A +AHE+ H LG+THD Sbjct: 170 GTTVGLAQVSTMCS-LESAAVNQDHSINPIGVASTMAHEMGHNLGMTHD 217 >UniRef50_UPI000069F93B Cluster: UPI000069F93B related cluster; n=1; Xenopus tropicalis|Rep: UPI000069F93B UniRef100 entry - Xenopus tropicalis Length = 190 Score = 35.5 bits (78), Expect = 1.5 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 3/47 (6%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHDGE 253 G A + +C+++ S + RD G++ A IAHE+ H LG+ HD E Sbjct: 99 GEAFLAQMCSESHSGGVIRDTGISPKELAKYIAHEIGHNLGMKHDTE 145 >UniRef50_A7SIU8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 336 Score = 35.5 bits (78), Expect = 1.5 Identities = 15/38 (39%), Positives = 22/38 (57%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235 G A + +C + ++ D GL +A +IAHEL H LG Sbjct: 184 GLAQMSAICVGAIAPSMSNDIGLQTAMIIAHELGHGLG 221 >UniRef50_A6EZB8 Cluster: Putative uncharacterized protein; n=1; Marinobacter algicola DG893|Rep: Putative uncharacterized protein - Marinobacter algicola DG893 Length = 542 Score = 35.1 bits (77), Expect = 2.0 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVC-TKTRSAAIDR--DEGLTSAFVIAHELAHLLGLTHD 247 G +G A VG VC ++ ++ I + T+A VIAHE+ H LG +HD Sbjct: 259 GSTAGLAWVGTVCYSQGYASGITNAYNSNATTAVVIAHEIGHNLGASHD 307 >UniRef50_Q45R48 Cluster: Salivary gland metalloprotease; n=1; Rhipicephalus microplus|Rep: Salivary gland metalloprotease - Boophilus microplus (Cattle tick) Length = 559 Score = 35.1 bits (77), Expect = 2.0 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 7/93 (7%) Frame = +2 Query: 8 SLEAINKWNY--RHLMKLPEGS---TGWDATIWLTR-SQLGGPSGFAPVGGVCTKTRSAA 169 SLE + Y RH P+ + TG+D + S+ G VGG+CT+ A Sbjct: 243 SLEQFRSYAYGKRHQFGNPDVTFLITGYDVYSTASGGSKSTSVLGIGYVGGLCTEYFVAL 302 Query: 170 IDRDEGL-TSAFVIAHELAHLLGLTHDGEAIVS 265 + GL T + HE H+LG HD VS Sbjct: 303 GEDSAGLYTGMHTLTHECGHVLGAAHDESRPVS 335 >UniRef50_Q19844 Cluster: Putative uncharacterized protein F27D9.7; n=2; Caenorhabditis|Rep: Putative uncharacterized protein F27D9.7 - Caenorhabditis elegans Length = 564 Score = 35.1 bits (77), Expect = 2.0 Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Frame = +2 Query: 77 DATIWLTRSQLGGPSGFAPVGGVCTKTRS--AAIDRDEGLTSAFVIAHELAHLLGLTH 244 D T+ L + GG A G+C+K + D + +A+V H+LAH++GLTH Sbjct: 20 DVTVLLRHNYEGG---IAYSNGICSKNSLMISGFLPDATMNNAWVFMHQLAHVIGLTH 74 >UniRef50_UPI0000F1ED1E Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 355 Score = 34.7 bits (76), Expect = 2.6 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Frame = +2 Query: 8 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPV------GGVCTKTRSAA 169 SL+++ +W + D +++TR L P+G V GGVC+ + Sbjct: 131 SLKSVCEWGQKVNPDADSDPLHADLLLYITRFDLVLPNGNKLVRGVTQFGGVCSTQWNCV 190 Query: 170 IDRDEGLTSAFVIAHELAHLLG 235 I D G IAHE+ H G Sbjct: 191 ITEDTGFDLGITIAHEIGHRAG 212 >UniRef50_A5NVS4 Cluster: Secretion protein HlyD family protein; n=2; Alphaproteobacteria|Rep: Secretion protein HlyD family protein - Methylobacterium sp. 4-46 Length = 1148 Score = 34.7 bits (76), Expect = 2.6 Identities = 16/46 (34%), Positives = 21/46 (45%) Frame = -2 Query: 610 PQGVPSRGGARFEPAHVRHSAVGTPQP*ARRPNLTDRHTEKPSPNS 473 P+ P R R +P H R A+ +P RP DRH P P + Sbjct: 887 PRAPPRRHDLRLDPFHERGGALRPHRPDGCRPGAGDRHARGPDPGA 932 >UniRef50_A3K869 Cluster: Putative uncharacterized protein; n=1; Sagittula stellata E-37|Rep: Putative uncharacterized protein - Sagittula stellata E-37 Length = 219 Score = 34.7 bits (76), Expect = 2.6 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 1/72 (1%) Frame = +1 Query: 523 VLKVVVCPPRYASRVPVQSERRLSREHPVDKTNGAWIVFCEXMPGPQLK-RLKVEKPNIL 699 +LK V P R ++R PV+ ERR + +GAW+ E PG LK RL E + Sbjct: 154 ILKRAVDPQRESNRRPVEGERRAA-------ADGAWLDALEDAPGAYLKARLAAEMARRI 206 Query: 700 QNGGRFGEXWKR 735 G E +R Sbjct: 207 AGGEAHAEERER 218 >UniRef50_UPI00015B4562 Cluster: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like - Nasonia vitripennis Length = 740 Score = 34.3 bits (75), Expect = 3.4 Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 13/118 (11%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG----------GPSGFAPVGGVCT 151 E++L+ I K+ ++ + P+ +D + +T S LG G +G A + G C Sbjct: 508 EETLKTIGKYFAKNFKEFPKDM--YDIVVGMTLSDLGDVDEAGKFNGGTTGIAYLKGACK 565 Query: 152 KTRSAA--IDRDEG-LTSAFVIAHELAHLLGLTHDGEAIVSLKRFEAL*WHRQYWLPY 316 A + RD G AHE+AH LG HD + + W Y + Y Sbjct: 566 LEYGFATGLVRDTGGFNGITTAAHEVAHALGAPHDSKEPADASQGPCS-WEEGYLMSY 622 >UniRef50_UPI0000DB717B Cluster: PREDICTED: similar to ADAMTS-7 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7); n=1; Apis mellifera|Rep: PREDICTED: similar to ADAMTS-7 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7) - Apis mellifera Length = 486 Score = 34.3 bits (75), Expect = 3.4 Identities = 16/42 (38%), Positives = 22/42 (52%) Frame = +2 Query: 113 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 G +G + + G C + AAI D GL + + IAH L H L Sbjct: 139 GFTGTSTIAGTCDPLKGAAIINDVGLHTGYHIAHHLGHTTDL 180 >UniRef50_Q09JE8 Cluster: Metalloprotease; n=2; Argasidae|Rep: Metalloprotease - Argas monolakensis Length = 269 Score = 34.3 bits (75), Expect = 3.4 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Frame = +2 Query: 68 TGWDATIWLTRSQLGGPSGFAPVGGVCTKTR-SAAIDRDEGLTSAFVIAHELAHLLGLTH 244 T D + ++++ G SG+A G CT + + D + AHE+AH LG H Sbjct: 64 TALDMILGEGKTRMVGVSGYAFCGAACTFYKFGESEDTPLSYDGTHLFAHEVAHTLGCVH 123 Query: 245 D 247 D Sbjct: 124 D 124 >UniRef50_Q2UTX6 Cluster: Predicted protein; n=1; Aspergillus oryzae|Rep: Predicted protein - Aspergillus oryzae Length = 213 Score = 34.3 bits (75), Expect = 3.4 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Frame = -3 Query: 330 PGK--VV*GSQYCRCHYRASKRFRLT-IASPSWVNPNK*ASSCAITKALVNPSSRSMAAD 160 PGK + G +Y + + R + +A S P + S +T A + P+ R A+ Sbjct: 76 PGKETALLGDKYLQTMANSKSRTSPSPVARASTSTPRAPSPSPLLTPATLPPAPRLRASP 135 Query: 159 RVLVQTPPTGANPEGPPSWDLVNHIVASHPVLPSGSFMRCL 37 +T P+ A P SW S PV PSG RCL Sbjct: 136 TSPARTAPSVAGPTRTASWPAPPPTAPSCPVTPSG---RCL 173 >UniRef50_UPI0000F2C3E0 Cluster: PREDICTED: hypothetical protein; n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical protein - Monodelphis domestica Length = 213 Score = 33.9 bits (74), Expect = 4.6 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Frame = -3 Query: 237 NPNK*ASSCAITKALVNPSSRSMAAD-RVLVQTPPTGANPEGPPSWDLVNHIVASHPVL 64 +PN +SS A T A +NP++ A D + +P G+N GP + + H +++ P L Sbjct: 43 SPNPTSSSAASTSAGLNPTTGKCAGDPGTAMNSPHPGSNTSGPTLYFISPHRLSNSPRL 101 >UniRef50_Q76KT5 Cluster: Meltrin epsilon; n=3; Gallus gallus|Rep: Meltrin epsilon - Gallus gallus (Chicken) Length = 775 Score = 33.9 bits (74), Expect = 4.6 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAID-- 175 E+ L N W R+L + +D T + G A VG +C + + Sbjct: 289 EEVLSNFNDWGNRYLSHRMK----YDVAHLFTYTDFELIVGLAYVGSICYPGYQSGLVSH 344 Query: 176 -RDEGLTSAFVIAHELAHLLGLTHD 247 R++ +T A + HEL H LG+ HD Sbjct: 345 IREDFVTFATIFTHELGHNLGMEHD 369 >UniRef50_Q7SCK1 Cluster: Predicted protein; n=1; Neurospora crassa|Rep: Predicted protein - Neurospora crassa Length = 1148 Score = 33.9 bits (74), Expect = 4.6 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Frame = -3 Query: 279 SKRFRLTIASPSWVNPNK*ASSCAITKALVNPSSRSMAADRVLVQTPPTGANPEGPPSW- 103 S R+ LT AS + + + A A+T AL + + S+ D +L P NP+ SW Sbjct: 538 SMRYTLTDASTALQSAQQSAVMAALTLALSSAVTTSINFDDILALARPYSDNPQFAASWV 597 Query: 102 -DLVN 91 DLVN Sbjct: 598 KDLVN 602 >UniRef50_Q90495 Cluster: Ecarin precursor; n=151; Colubroidea|Rep: Ecarin precursor - Echis carinatus (Saw-scaled viper) Length = 616 Score = 33.9 bits (74), Expect = 4.6 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247 G V G+C RS + D A++IAHE+ H LG+ HD Sbjct: 304 GITFVYGMCKSDRSVELILDYSNITFNMAYIIAHEMGHSLGMLHD 348 >UniRef50_Q9H013 Cluster: ADAM 19 precursor; n=34; Euteleostomi|Rep: ADAM 19 precursor - Homo sapiens (Human) Length = 956 Score = 33.9 bits (74), Expect = 4.6 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247 G G AP+ +C+ +S ++ D + A +AHE+ H G+THD Sbjct: 309 GTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHD 357 >UniRef50_UPI00015B49E4 Cluster: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to A disintegrin and metalloproteinase with thrombospondin motifs like - Nasonia vitripennis Length = 593 Score = 33.5 bits (73), Expect = 6.0 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 7/50 (14%) Frame = +2 Query: 122 GFAPVGGVCT----KTRSAAIDRDE---GLTSAFVIAHELAHLLGLTHDG 250 G+A GG CT +T+ A+ E G AHE+ HLLG HDG Sbjct: 375 GYAVRGGACTVNIRETKMEAVGLVEDNGGYVGIIPAAHEVGHLLGAPHDG 424 >UniRef50_A6H8I8 Cluster: LOC100101326 protein; n=1; Xenopus laevis|Rep: LOC100101326 protein - Xenopus laevis (African clawed frog) Length = 828 Score = 33.5 bits (73), Expect = 6.0 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 3/45 (6%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247 G A + +C+ S + D +T A +AH+L H LGL+HD Sbjct: 308 GMATMNSMCSAGYSGGVSMDHSVTILGVASTLAHQLGHNLGLSHD 352 >UniRef50_Q7NFJ0 Cluster: Glr3535 protein; n=1; Gloeobacter violaceus|Rep: Glr3535 protein - Gloeobacter violaceus Length = 169 Score = 33.5 bits (73), Expect = 6.0 Identities = 21/74 (28%), Positives = 31/74 (41%) Frame = +2 Query: 59 EGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238 EG W + W+T + S +G + R AA+ +V+ HELAHL+ Sbjct: 75 EGCLEWQSIRWVTNQEARWGSCTPTLGTIRLSHRLAALP---AFVRDYVLVHELAHLVEP 131 Query: 239 THDGEAIVSLKRFE 280 H + RFE Sbjct: 132 NHGPRFWALVNRFE 145 >UniRef50_Q3KBK8 Cluster: Leucine-rich repeat; n=1; Pseudomonas fluorescens PfO-1|Rep: Leucine-rich repeat - Pseudomonas fluorescens (strain PfO-1) Length = 1593 Score = 33.5 bits (73), Expect = 6.0 Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 3/34 (8%) Frame = +1 Query: 286 VMAPTVLATLHNFAWSSCSKEQFHAKSK---KWW 378 + P + A LHNFA S C E FH S +WW Sbjct: 135 IKLPLLQAALHNFAASECEPEAFHDSSGFLIEWW 168 >UniRef50_A1IIB0 Cluster: Metalloprotease; n=2; Haemaphysalis longicornis|Rep: Metalloprotease - Haemaphysalis longicornis (Bush tick) Length = 550 Score = 33.5 bits (73), Expect = 6.0 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Frame = +2 Query: 122 GFAPVGGVCTKTRSAAIDRDEGL-TSAFVIAHELAHLLGLTHDGE 253 G + GVC+ + A + G T HE+AH LG THDG+ Sbjct: 290 GIGYLSGVCSHSFVALGEDKPGFFTGLRTFTHEVAHTLGATHDGQ 334 >UniRef50_Q8R534 Cluster: ADAM 1b precursor; n=36; Eutheria|Rep: ADAM 1b precursor - Mus musculus (Mouse) Length = 806 Score = 33.5 bits (73), Expect = 6.0 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Frame = +2 Query: 2 EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAID-- 175 + +L N W L+ G D + + G G A + G C+ +AA++ Sbjct: 269 QTTLRNFNFWRQEKLV----GRVRHDVAHLIVGHRPGENEGQAFLRGACSGEFAAAVEAF 324 Query: 176 -RDEGLTSAFVIAHELAHLLGLTHD 247 ++ L A ++AHEL H LG+ HD Sbjct: 325 HHEDVLLFAALMAHELGHNLGIQHD 349 >UniRef50_P78325 Cluster: ADAM 8 precursor; n=21; Eutheria|Rep: ADAM 8 precursor - Homo sapiens (Human) Length = 824 Score = 33.5 bits (73), Expect = 6.0 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHDG--EAIVSLKR 274 G GFA V +C+ + S A+++D A +AHE+ H LG+ HD + +R Sbjct: 298 GTTVGFARVSAMCSHS-SGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQER 356 Query: 275 FEA 283 FEA Sbjct: 357 FEA 359 >UniRef50_UPI00015553DB Cluster: PREDICTED: similar to chemokine receptor; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to chemokine receptor - Ornithorhynchus anatinus Length = 405 Score = 33.1 bits (72), Expect = 8.0 Identities = 16/34 (47%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Frame = -3 Query: 204 TKALVNPSSRSMAADRVLVQTPP-TGANPEGPPS 106 +++L + SSRS +DR+L PP T +NP GP S Sbjct: 303 SQSLPSASSRSSGSDRILWPPPPATSSNPTGPAS 336 >UniRef50_UPI00005A5000 Cluster: PREDICTED: similar to a disintegrin and metalloproteinase domain 8 precursor; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to a disintegrin and metalloproteinase domain 8 precursor - Canis familiaris Length = 902 Score = 33.1 bits (72), Expect = 8.0 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 4/50 (8%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS----AFVIAHELAHLLGLTHD 247 G G A V +C++ S A+++D L + A +AHE+ H LG+ HD Sbjct: 279 GTTVGLAKVSAMCSRD-SGAVNQDHSLGNPVGVASTMAHEMGHNLGMDHD 327 >UniRef50_UPI0000510397 Cluster: COG1414: Transcriptional regulator; n=1; Brevibacterium linens BL2|Rep: COG1414: Transcriptional regulator - Brevibacterium linens BL2 Length = 245 Score = 33.1 bits (72), Expect = 8.0 Identities = 20/72 (27%), Positives = 33/72 (45%) Frame = -3 Query: 282 ASKRFRLTIASPSWVNPNK*ASSCAITKALVNPSSRSMAADRVLVQTPPTGANPEGPPSW 103 AS+ L P++ + + A ++ V+ RS+ +++ Q P T GP Sbjct: 18 ASRLLELLAQGPAFHHLTELAQESGMSVPTVHRLLRSLTIAKLVSQDPTTARYGLGPELT 77 Query: 102 DLVNHIVASHPV 67 L NH V+ HPV Sbjct: 78 RLSNHFVSRHPV 89 >UniRef50_Q4SW11 Cluster: Chromosome undetermined SCAF13694, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome undetermined SCAF13694, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 569 Score = 33.1 bits (72), Expect = 8.0 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Frame = +2 Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDE---GLTSAFVIAHELAHLLGLTHD 247 G G A +C+ RS + D L A +AHEL H LG++HD Sbjct: 63 GTTVGMASQSSMCSTDRSGGVSVDHLVSVLGVASTVAHELGHNLGMSHD 111 >UniRef50_Q7MTD8 Cluster: Putative uncharacterized protein; n=1; Porphyromonas gingivalis|Rep: Putative uncharacterized protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 859 Score = 33.1 bits (72), Expect = 8.0 Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Frame = +2 Query: 125 FAPVGGVCTKTRSAAIDRDEGLTSA--FVIAHELAHLLGLTHDGEAIVSLKRFEAL*WHR 298 F G V + R A D DE + + +V AHE+ H +GL H+ A S E L Sbjct: 408 FVQTGAVDPRVRKAVFD-DEVMRESLRYVAAHEIGHTIGLMHNMGASYSF-TIENL-RDP 464 Query: 299 QYWLPYTTLPGQV-VQRNNFM 358 Q+ Y T P + RNNF+ Sbjct: 465 QFTQKYGTTPSIMDYARNNFV 485 >UniRef50_A7SIU7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 755 Score = 33.1 bits (72), Expect = 8.0 Identities = 12/23 (52%), Positives = 15/23 (65%) Frame = +3 Query: 561 TCAGSKRAPPLEGTPCGQNQWCV 629 TC+ S PPL+GT CG WC+ Sbjct: 91 TCSSSV-VPPLDGTRCGPRHWCI 112 >UniRef50_Q2GV16 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 608 Score = 33.1 bits (72), Expect = 8.0 Identities = 13/38 (34%), Positives = 18/38 (47%) Frame = +1 Query: 73 MGRHNMVDEIPAWRAFRIRPRRWGLHQNAVSRHRPRRR 186 M RH+ P W F+ P + LHQ H P+R+ Sbjct: 266 MSRHSRPQPYPHWTGFQSAPSSYDLHQEYEESHLPQRK 303 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 887,595,107 Number of Sequences: 1657284 Number of extensions: 20123659 Number of successful extensions: 58712 Number of sequences better than 10.0: 170 Number of HSP's better than 10.0 without gapping: 55191 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 58608 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 65438977305 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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