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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbVm1459
         (636 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.      102   9e-22
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   102   9e-22
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   102   9e-22
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   102   9e-22
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.      102   9e-22
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.             102   9e-22
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p...   100   9e-21
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f...   100   9e-21
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f...   100   9e-21
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f...   100   9e-21
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ...   100   9e-21
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.      100   9e-21
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va...    98   2e-20
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.                 96   1e-19
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.               96   1e-19
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.              96   1e-19
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant...    96   1e-19
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p...    94   3e-19
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    94   3e-19
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    94   3e-19
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    94   3e-19
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    94   3e-19
AK123000-1|BAC85516.1| 1176|Homo sapiens  3 (HIVEP3).  protein.        94   3e-19
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.                   93   6e-19
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl...    93   6e-19
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl...    93   6e-19
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.              93   6e-19
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs...    86   9e-17
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso...    86   9e-17
AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    86   9e-17
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    86   9e-17
AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    86   9e-17
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.                 86   9e-17
AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isofor...    86   9e-17
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag...    84   3e-16
U77493-1|AAB19224.1|  263|Homo sapiens Notch2 protein.                 84   3e-16
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.               84   3e-16
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag...    84   3e-16
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd...    84   3e-16
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd...    84   3e-16
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd...    84   3e-16
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd...    84   3e-16
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J...    84   3e-16
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.              84   3e-16
AY358892-1|AAQ89251.1|  723|Homo sapiens DLL1 protein.                 83   6e-16
AL078605-2|CAB89569.1|  723|Homo sapiens delta-like 1 (Drosophil...    83   6e-16
AF222310-1|AAG09716.1|  723|Homo sapiens Delta1 protein.               83   6e-16
AF196571-1|AAF05834.1|  723|Homo sapiens Delta-like-1 protein pr...    83   6e-16
AF003522-1|AAB61286.1|  723|Homo sapiens Delta protein.                83   6e-16
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.                 83   6e-16
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.     83   8e-16
BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.       82   2e-15
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ...    82   2e-15
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.        81   3e-15
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.              81   3e-15
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.         81   3e-15
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.              81   3e-15
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.             81   3e-15
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.             81   3e-15
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.                 80   6e-15
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.                 80   6e-15
D86566-1|BAA13116.1|  955|Homo sapiens notch related protein pro...    80   6e-15
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    80   6e-15
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    80   6e-15
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop...    80   6e-15
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso...    80   6e-15
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso...    80   6e-15
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop...    80   6e-15
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph...    80   7e-15
BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophil...    80   7e-15
AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.                 80   7e-15
AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.              80   7e-15
AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.    80   7e-15
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.                80   7e-15
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula...    80   7e-15
AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.              80   7e-15
AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2 pr...    80   7e-15
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.       80   7e-15
AL450324-2|CAI13283.1|  186|Homo sapiens protein ( Human DNA seq...    79   1e-14
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ...    79   2e-14
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph...    78   2e-14
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph...    78   2e-14
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph...    78   2e-14
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph...    78   2e-14
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph...    78   2e-14
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.       78   2e-14
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.                78   2e-14
BC000218-1|AAH00218.1|  618|Homo sapiens delta-like 3 (Drosophil...    78   3e-14
AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    78   3e-14
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    78   3e-14
AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    78   3e-14
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt...    78   3e-14
AF241373-1|AAF62542.1|  618|Homo sapiens DLL3 protein precursor ...    78   3e-14
AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.               78   3e-14
AK075302-1|BAC11535.1|  587|Homo sapiens protein ( Homo sapiens ...    77   4e-14
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph...    75   2e-13
BC090943-1|AAH90943.1|  249|Homo sapiens NOTCH2NL protein protein.     75   2e-13
BC065219-1|AAH65219.2|  236|Homo sapiens Notch homolog 2 (Drosop...    75   2e-13
BC019835-1|AAH19835.1|  236|Homo sapiens Notch homolog 2 N-termi...    75   2e-13
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.                75   2e-13
AF075240-1|AAD19336.1|  850|Homo sapiens SLIT1 protein protein.        75   2e-13
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.       75   2e-13
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.                75   2e-13
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro...    75   2e-13
BC035009-1|AAH35009.1|  737|Homo sapiens delta/notch-like EGF re...    75   2e-13
BC024766-1|AAH24766.2|  454|Homo sapiens DNER protein protein.         75   2e-13
AY358891-1|AAQ89250.1|  737|Homo sapiens QPRR262 protein.              75   2e-13
AL137311-1|CAB70690.1|  252|Homo sapiens hypothetical protein pr...    75   2e-13
AF442487-1|AAM21557.1|  737|Homo sapiens delta-notch-like EGF re...    75   2e-13
Z12172-1|CAA78163.1|  383|Homo sapiens putative homeotic protein...    75   3e-13
U77914-1|AAC50909.1|  263|Homo sapiens soluble protein Jagged pr...    75   3e-13
U15981-1|AAA75365.1|  310|Homo sapiens dlk protein.                    75   3e-13
U15979-1|AAA75364.1|  382|Homo sapiens dlk protein.                    75   3e-13
DQ309460-1|ABC26875.1|  231|Homo sapiens delta-like 1 protein.         75   3e-13
DQ138965-1|AAZ66768.1|  203|Homo sapiens truncated brevideltinin...    75   3e-13
DQ126100-1|AAZ38943.1|  212|Homo sapiens brevideltin protein.          75   3e-13
DQ017081-1|AAY40461.1|  315|Homo sapiens secredeltin protein.          75   3e-13
BC014015-1|AAH14015.1|  383|Homo sapiens delta-like 1 homolog (D...    75   3e-13
BC013197-1|AAH13197.1|  383|Homo sapiens delta-like 1 homolog (D...    75   3e-13
BC007741-1|AAH07741.1|  383|Homo sapiens delta-like 1 homolog (D...    75   3e-13
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro...    75   3e-13
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro...    75   3e-13
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p...    74   4e-13
BX537434-1|CAD97676.1|  236|Homo sapiens hypothetical protein pr...    74   4e-13
BC084572-1|AAH84572.1|  343|Homo sapiens NOTCH2NL protein protein.     74   4e-13
BC010154-1|AAH10154.3|  236|Homo sapiens Notch homolog 2 (Drosop...    74   4e-13
AL592307-2|CAH73994.1|  230|Homo sapiens Notch homolog 2 (Drosop...    74   4e-13
AL592307-1|CAH73993.1|  236|Homo sapiens Notch homolog 2 (Drosop...    74   4e-13
AK075065-1|BAC11381.1|  269|Homo sapiens protein ( Homo sapiens ...    74   4e-13
AC008273-1|AAF19247.2|  291|Homo sapiens unknown protein.              74   5e-13
AL359813-8|CAI23223.1|  377|Homo sapiens EGF-like-domain, multip...    72   2e-12
BC027939-1|AAH27939.1|  600|Homo sapiens SNED1 protein protein.        71   3e-12
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.              71   5e-12
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.              71   5e-12
BX640729-1|CAE45845.1|  674|Homo sapiens hypothetical protein pr...    71   5e-12
AL136322-1|CAI16644.1|  674|Homo sapiens crumbs homolog 1 (Droso...    71   5e-12
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.          71   5e-12
BC008761-1|AAH08761.2|  743|Homo sapiens LTBP3 protein protein.        70   6e-12
AL117551-1|CAB55988.1|  511|Homo sapiens hypothetical protein pr...    70   6e-12
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.     70   6e-12
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro...    70   6e-12
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact...    70   8e-12
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact...    70   8e-12
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact...    70   8e-12
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami...    70   8e-12
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re...    70   8e-12
AB208840-1|BAD92077.1|  830|Homo sapiens fibrillin 1 variant pro...    70   8e-12
AL355357-1|CAI16435.1|   95|Homo sapiens protein ( Human DNA seq...    69   1e-11
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven...    69   1e-11
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven...    69   1e-11
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven...    69   1e-11
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ...    69   1e-11
D89629-1|BAB46925.1|  815|Homo sapiens cerebral protein-12 protein.    69   1e-11
D83018-1|BAA11681.1|  816|Homo sapiens nel-related protein 2 pro...    69   1e-11
BC020544-1|AAH20544.1|  816|Homo sapiens NELL2 protein protein.        69   1e-11
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.       69   2e-11
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven...    69   2e-11
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.           69   2e-11
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel...    69   2e-11
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ...    68   2e-11
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ...    68   2e-11
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote...    68   2e-11
J02814-1|AAA36437.1|  688|Homo sapiens protein ( Human chondroit...    68   2e-11
D32039-1|BAA06801.1|  655|Homo sapiens proteoglycan PG-M(V3) pro...    68   2e-11
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr...    68   2e-11
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro...    68   2e-11
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.       68   3e-11
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ...    68   3e-11
BC110320-1|AAI10321.1|  383|Homo sapiens delta-like 2 homolog (D...    67   6e-11
AY358126-1|AAQ88493.1|  383|Homo sapiens PSGC2903 protein.             67   6e-11
AL359813-9|CAI23224.1|  383|Homo sapiens EGF-like-domain, multip...    67   6e-11
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F...    66   1e-10
AL359813-6|CAI23221.1|  288|Homo sapiens EGF-like-domain, multip...    66   1e-10
AL137007-1|CAC10575.2|  199|Homo sapiens novel EGF-like domain c...    66   1e-10
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.            65   2e-10
AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein.             65   2e-10
AC005254-1|AAC25581.1|  315|Homo sapiens PGCN_HUMAN, PARTIAL CDS...    65   2e-10
AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p...    65   2e-10
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital...    65   2e-10
D83017-1|BAA11680.1|  810|Homo sapiens nel-related protein protein.    65   2e-10
BC096102-1|AAH96102.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    65   2e-10
BC096101-1|AAH96101.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    65   2e-10
BC069674-1|AAH69674.1|  810|Homo sapiens nel-like 1, precursor p...    65   2e-10
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ...    65   2e-10
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ...    65   2e-10
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ...    65   2e-10
AK131282-1|BAD18457.1|  872|Homo sapiens protein ( Homo sapiens ...    65   2e-10
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.          65   2e-10
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.          65   2e-10
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.          65   2e-10
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.          65   2e-10
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.          65   2e-10
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.           65   2e-10
L32137-1|AAA57253.1|  757|Homo sapiens matrix protein protein.         64   5e-10
BC125092-1|AAI25093.1|  757|Homo sapiens cartilage oligomeric ma...    64   5e-10
BC110847-1|AAI10848.1|  757|Homo sapiens cartilage oligomeric ma...    64   5e-10
AC003107-1|AAB86501.1|  817|Homo sapiens COMP_HUMAN protein.           64   5e-10
AB086984-1|BAC53888.1|  757|Homo sapiens cartilage oligomeric ma...    64   5e-10
X62009-1|CAB56757.1|  754|Homo sapiens fibrillin 5 protein.            63   7e-10
AK223216-1|BAD96936.1|  757|Homo sapiens cartilage oligomeric ma...    63   7e-10
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.       62   1e-09
X62008-1|CAB56534.1|  517|Homo sapiens fibrillin 15 protein.           62   1e-09
U57523-1|AAB06946.1|  446|Homo sapiens protein ( Human nel homol...    62   1e-09
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt...    62   1e-09
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro...    62   1e-09
AF054502-1|AAC39882.1|  669|Homo sapiens latent transforming gro...    62   1e-09
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro...    62   1e-09
X81479-1|CAA57232.1|  886|Homo sapiens EMR1 protein.                   62   2e-09
DQ217942-1|ABB70739.1|  886|Homo sapiens EGF-like module contain...    61   4e-09
BC059395-1|AAH59395.1|  821|Homo sapiens EMR1 protein protein.         61   4e-09
AB065918-1|BAC06133.1|  929|Homo sapiens seven transmembrane hel...    61   4e-09
AB024578-1|BAA88952.1|   78|Homo sapiens notch4 protein.               61   4e-09
BC053656-1|AAH53656.1|  470|Homo sapiens EDIL3 protein protein.        60   6e-09
U89336-6|AAB47494.1|  293|Homo sapiens NG3 protein.                    60   9e-09
BX284686-12|CAM26220.1|  293|Homo sapiens EGF-like-domain, multi...    60   9e-09
BC052591-1|AAH52591.1|  293|Homo sapiens EGF-like-domain, multip...    60   9e-09
BC035574-1|AAH35574.1|  293|Homo sapiens EGF-like-domain, multip...    60   9e-09
AY358139-1|AAQ88506.1|  293|Homo sapiens NG3 protein.                  60   9e-09
AL845464-11|CAI41800.2|  293|Homo sapiens EGF-like-domain, multi...    60   9e-09
AL662884-17|CAI18345.2|  293|Homo sapiens EGF-like-domain, multi...    60   9e-09
AL662828-17|CAI17428.1|  293|Homo sapiens EGF-like-domain, multi...    60   9e-09
AB190520-1|BAD51398.1|  293|Homo sapiens VE-statin2 protein.           60   9e-09
X12892-1|CAA31383.1|  650|Homo sapiens protein ( H.sapiens mRNA ...    59   1e-08
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.                  59   1e-08
M14338-1|AAA60181.1|  650|Homo sapiens protein S precursor protein.    59   1e-08
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro...    59   1e-08
BC039143-1|AAH39143.1|  740|Homo sapiens FAT2 protein protein.         59   1e-08
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac...    59   1e-08
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro...    59   1e-08
AC019127-1|AAY24260.1|  697|Homo sapiens unknown protein.              59   1e-08
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro...    59   1e-08
AB177851-1|BAD66829.1|  573|Homo sapiens KIAA0811 splice variant...    59   1e-08
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein.     59   1e-08
AB011535-1|BAA32463.1|  573|Homo sapiens MEGF1 protein.                59   1e-08
AK074499-1|BAC11024.1|  636|Homo sapiens protein ( Homo sapiens ...    59   1e-08
Y00692-1|CAA68687.1|  676|Homo sapiens preproprotein S protein.        58   2e-08
M57853-1|AAA60357.1|  676|Homo sapiens S protein protein.              58   2e-08
M36564-1|AAA60180.1|  650|Homo sapiens PROS1 protein.                  58   2e-08
M15036-1|AAA36479.1|  676|Homo sapiens protein ( Human vitamin K...    58   2e-08
BC126986-1|AAI26987.1|  393|Homo sapiens FLJ37440 protein protein.     58   2e-08
BC015801-1|AAH15801.1|  676|Homo sapiens PROS1 protein protein.        58   2e-08
AY308744-1|AAP45054.1|  497|Homo sapiens protein S (alpha) protein.    58   2e-08
AK074396-1|BAB85069.1|  220|Homo sapiens protein ( Homo sapiens ...    58   2e-08
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec...    58   3e-08
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein...    58   3e-08
BC111690-1|AAI11691.1|  807|Homo sapiens SCUBE2 protein protein.       58   3e-08
AK131552-1|BAD18686.1|  682|Homo sapiens protein ( Homo sapiens ...    58   3e-08
AK123039-1|BAC85521.1|  971|Homo sapiens protein ( Homo sapiens ...    58   3e-08
AJ400877-1|CAB92285.1|  999|Homo sapiens CEGP1 protein protein.        58   3e-08
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re...    58   3e-08
AF054501-1|AAC39881.1|  161|Homo sapiens latent transforming gro...    58   3e-08
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein...    58   3e-08
BC038587-1|AAH38587.1|  553|Homo sapiens EGF-like-domain, multip...    57   5e-08
AY358333-1|AAQ88699.1|  338|Homo sapiens EGFL6 protein.                57   5e-08
AK075214-1|BAC11477.1|  553|Homo sapiens protein ( Homo sapiens ...    57   5e-08
AJ245671-1|CAB92132.1|  554|Homo sapiens hypothetical protein pr...    57   5e-08
AF193055-1|AAG22483.1|  474|Homo sapiens unknown protein.              57   5e-08
AF186084-1|AAF27812.1|  553|Homo sapiens epidermal growth factor...    57   5e-08
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq...    56   8e-08
AK131562-1|BAD18695.1|  867|Homo sapiens protein ( Homo sapiens ...    56   8e-08
AK074075-1|BAB84901.1|  522|Homo sapiens FLJ00146 protein protein.     56   8e-08
AK027344-1|BAB55049.1|  741|Homo sapiens protein ( Homo sapiens ...    56   8e-08
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.            56   8e-08
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein...    56   8e-08
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.           56   8e-08
AC013451-1|AAF87081.1|  969|Homo sapiens LTBP-2 protein.               56   1e-07
Z98047-1|CAI19628.1|  703|Homo sapiens fibulin 1 protein.              56   1e-07
Z95331-3|CAI41717.1|  703|Homo sapiens fibulin 1 protein.              56   1e-07
X53743-1|CAA37772.1|  683|Homo sapiens fibulin-1 C protein.            56   1e-07
X53742-1|CAA37771.1|  601|Homo sapiens fibulin-1 B protein.            56   1e-07
X53741-1|CAA37770.1|  566|Homo sapiens fibulin-1 A protein.            56   1e-07
U70312-1|AAC02648.1|  480|Homo sapiens integrin binding protein ...    56   1e-07
U01244-1|AAB17099.1|  703|Homo sapiens fibulin-1D protein.             56   1e-07
BC030828-1|AAH30828.1|  480|Homo sapiens EGF-like repeats and di...    56   1e-07
BC022497-1|AAH22497.1|  683|Homo sapiens fibulin 1 protein.            56   1e-07
AL359813-7|CAI23222.1|  134|Homo sapiens EGF-like-domain, multip...    56   1e-07
AL021391-3|CAI18930.1|  703|Homo sapiens fibulin 1 protein.            56   1e-07
AK075566-1|BAC11705.1|  638|Homo sapiens protein ( Homo sapiens ...    56   1e-07
AF217999-1|AAG17241.1|  495|Homo sapiens unknown protein.              56   1e-07
AF126110-1|AAK37822.1|  703|Homo sapiens fibulin-1 isoform D pre...    56   1e-07
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr...    56   1e-07
U03877-1|AAA65590.1|  387|Homo sapiens extracellular protein pro...    55   2e-07
BC098561-1|AAH98561.1|  493|Homo sapiens EGF-containing fibulin-...    55   2e-07
BC014410-1|AAH14410.1|  493|Homo sapiens EGF-containing fibulin-...    55   2e-07
BC006425-1|AAH06425.1|  204|Homo sapiens EGFL9 protein protein.        55   2e-07
BC000230-1|AAH00230.1|  204|Homo sapiens EGFL9 protein protein.        55   2e-07
AY004330-1|AAK11491.1|  493|Homo sapiens EGF-containing fibulin-...    55   2e-07
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai...    55   2e-07
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai...    55   2e-07
AC010895-1|AAY14669.1|  320|Homo sapiens unknown protein.              55   2e-07
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein...    55   2e-07
AB209212-1|BAD92449.1|  418|Homo sapiens EGF-containing fibulin-...    55   2e-07
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.                55   2e-07
U70313-1|AAC02649.1|  125|Homo sapiens integrin binding protein ...    55   2e-07
BC142624-1|AAI42625.1|  955|Homo sapiens von Willebrand factor C...    55   2e-07
BC096103-1|AAH96103.1|  763|Homo sapiens NELL1 protein protein.        55   2e-07
BC096100-1|AAH96100.1|  763|Homo sapiens NELL1 protein protein.        55   2e-07
AK056571-1|BAB71219.1|  955|Homo sapiens protein ( Homo sapiens ...    55   2e-07
AK126775-1|BAC86684.1|  952|Homo sapiens protein ( Homo sapiens ...    54   3e-07
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr...    54   4e-07
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr...    54   4e-07
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p...    54   4e-07
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f...    54   4e-07
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ...    54   4e-07
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.              54   6e-07
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.            54   6e-07
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.            54   6e-07
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.            54   6e-07
Z99756-1|CAI18854.1|  988|Homo sapiens protein ( Human DNA seque...    53   1e-06
Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...    53   1e-06
Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...    53   1e-06
Z82214-3|CAI21674.1|  988|Homo sapiens protein ( Human DNA seque...    53   1e-06
Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...    53   1e-06
BC127263-1|AAI27264.1|  363|Homo sapiens SCUBE1 protein protein.       53   1e-06
BC047916-1|AAH47916.1|  347|Homo sapiens SCUBE1 protein protein.       53   1e-06
AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...    53   1e-06
AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...    53   1e-06
AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...    53   1e-06
AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein.          53   1e-06
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.       52   1e-06
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.                 52   1e-06
BC150250-1|AAI50251.1| 2570|Homo sapiens stabilin 1 protein.           52   1e-06
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.           52   1e-06
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.               52   1e-06
BC000059-1|AAH00059.2|  771|Homo sapiens CELSR1 protein protein.       52   2e-06
AK027618-1|BAB55237.1|  849|Homo sapiens protein ( Homo sapiens ...    52   2e-06
U94333-1|AAB53110.1|  652|Homo sapiens C1qR(p) protein.                51   3e-06
S54426-1|AAB25244.1|  109|Homo sapiens fibrillin protein.              51   3e-06
BC028075-1|AAH28075.1|  652|Homo sapiens CD93 molecule protein.        51   3e-06
AL118508-1|CAC00597.1|  652|Homo sapiens complement component 1,...    51   3e-06
AJ295142-1|CAC82720.1|  652|Homo sapiens C1q receptor protein pr...    51   3e-06
AF525689-1|AAN77133.1|  988|Homo sapiens signal peptide-CUB-EGF-...    51   3e-06
AC020594-1|AAY15036.1|  150|Homo sapiens unknown protein.              51   3e-06
AB209895-1|BAD93132.1|  671|Homo sapiens complement component 1,...    51   3e-06
X02750-1|CAA26528.1|  461|Homo sapiens protein ( Human liver mRN...    51   4e-06
M59303-1|AAA36499.1|  320|Homo sapiens protein Z protein.              51   4e-06
M55671-1|AAA36501.1|  422|Homo sapiens protein Z protein.              51   4e-06
M55670-1|AAA36500.1|  400|Homo sapiens protein Z protein.              51   4e-06
M12712-1|AAA60165.1|  462|Homo sapiens PROC protein.                   51   4e-06
M11228-1|AAA60166.1|  461|Homo sapiens protein ( Human protein C...    51   4e-06
BC074907-1|AAH74907.1|  400|Homo sapiens protein Z, vitamin K-de...    51   4e-06
BC074906-1|AAH74906.1|  400|Homo sapiens protein Z, vitamin K-de...    51   4e-06
BC034377-1|AAH34377.1|  461|Homo sapiens protein C (inactivator ...    51   4e-06
AL137002-16|CAI41388.1|  400|Homo sapiens protein Z, vitamin K-d...    51   4e-06
AL137002-15|CAI41389.1|  422|Homo sapiens protein Z, vitamin K-d...    51   4e-06
AF440358-1|AAL27631.1|  400|Homo sapiens protein Z, vitamin K-de...    51   4e-06
AF378903-1|AAK56377.1|  461|Homo sapiens protein C protein.            51   4e-06
AC068282-2|AAY15044.1|  461|Homo sapiens unknown protein.              51   4e-06
AB033749-2|BAA85764.1|  422|Homo sapiens protein Z spliced varia...    51   4e-06
AB033749-1|BAA85763.1|  400|Homo sapiens protein Z protein.            51   4e-06
L13720-1|AAA58494.1|  678|Homo sapiens growth-arrest-specific pr...    50   5e-06
EF631974-1|ABR09277.1|  678|Homo sapiens growth arrest-specific ...    50   5e-06
BX072579-3|CAH71174.1|  678|Homo sapiens growth arrest-specific ...    50   5e-06
BC038984-1|AAH38984.1|  678|Homo sapiens growth arrest-specific ...    50   5e-06
AY358336-1|AAQ88702.1|  509|Homo sapiens DFLL295 protein.              50   5e-06
AY256843-1|AAO84057.1|  678|Homo sapiens growth arrested-specifi...    50   5e-06
AK126533-1|BAC86580.1|  624|Homo sapiens protein ( Homo sapiens ...    50   5e-06
CR541934-1|CAG46732.1|  443|Homo sapiens EFEMP2 protein.               50   7e-06
BC010456-1|AAH10456.1|  443|Homo sapiens EGF-containing fibulin-...    50   7e-06
AY358899-1|AAQ89258.1|  443|Homo sapiens EFEMP2 protein.               50   7e-06
AY358898-1|AAQ89257.1|  448|Homo sapiens FBLN5 protein.                50   7e-06
AJ132819-1|CAA10791.2|  443|Homo sapiens fibulin-4 protein.            50   7e-06
AF124486-1|AAG45245.1|  443|Homo sapiens fibulin-like extracellu...    50   7e-06
AF109121-1|AAF65188.1|  443|Homo sapiens EGF-containing fibulin-...    50   7e-06
AF093119-1|AAC62108.1|  439|Homo sapiens UPH1 protein.                 50   7e-06
AB030655-1|BAA92880.1|  443|Homo sapiens mutant p53 binding prot...    50   7e-06
M17778-1|AAA36799.1|  640|Homo sapiens protein ( Human uromoduli...    50   9e-06
M15881-1|AAA36798.1|  640|Homo sapiens protein ( Human uromoduli...    50   9e-06
BC035975-1|AAH35975.1|  611|Homo sapiens UMOD protein protein.         50   9e-06
AY162970-1|AAO64446.1|  640|Homo sapiens uromodulin precursor pr...    50   9e-06
AK222891-1|BAD96611.1|  810|Homo sapiens egf-like module contain...    50   9e-06
AF114491-1|AAF21974.1|  823|Homo sapiens EGF-like module EMR2 pr...    50   9e-06
AB065931-1|BAC06146.1|  837|Homo sapiens seven transmembrane hel...    50   9e-06
X94630-1|CAA64333.1|  835|Homo sapiens seven-span transmembrane ...    49   1e-05
X71923-1|CAA50739.1|  750|Homo sapiens tenascin-X precursor prot...    49   1e-05
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ...    49   1e-05
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein.             49   1e-05
U76764-1|AAB36682.1|  835|Homo sapiens CD97 protein.                   49   1e-05
L38969-1|AAC41762.1|  956|Homo sapiens thrombospondin 3 protein.       49   1e-05
BC127005-1|AAI27006.1|  823|Homo sapiens egf-like module contain...    49   1e-05
BC127004-1|AAI27005.1|  823|Homo sapiens egf-like module contain...    49   1e-05
BC113847-1|AAI13848.1|  956|Homo sapiens thrombospondin 3, precu...    49   1e-05
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor...    49   1e-05
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor...    49   1e-05
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro...    49   1e-05
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein.          49   1e-05
AL713999-15|CAI95084.1|  956|Homo sapiens thrombospondin 3 protein.    49   1e-05
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein.          49   1e-05
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein.         49   1e-05
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein.          49   1e-05
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein.          49   1e-05
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB...    49   1e-05
AK223278-1|BAD96998.1|  956|Homo sapiens thrombospondin 3 precur...    49   1e-05
AF023268-6|AAC51818.1|  736|Homo sapiens thrombospondin3 protein.      49   1e-05
AB065966-1|BAC06178.1|  837|Homo sapiens seven transmembrane hel...    49   1e-05
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly...    49   2e-05
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.                 49   2e-05
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog...    49   2e-05
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog...    49   2e-05
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog...    49   2e-05
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.     49   2e-05
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.           49   2e-05
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci...    49   2e-05
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.               49   2e-05
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h...    48   2e-05
BC133013-1|AAI33014.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
BC133011-1|AAI33012.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
BC109204-1|AAI09205.1|  351|Homo sapiens HSPG2 protein protein.        48   2e-05
BC053933-1|AAH53933.1|  239|Homo sapiens EMR2 protein protein.         48   2e-05
BC034949-1|AAH34949.1|  239|Homo sapiens EMR2 protein protein.         48   2e-05
BC020198-1|AAH20198.1|  567|Homo sapiens MEGF10 protein protein.       48   2e-05
AY358133-1|AAQ88500.1|  594|Homo sapiens TDKS9424 protein.             48   2e-05
AL589916-3|CAM13294.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL589916-2|CAI12363.2|  619|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL365217-4|CAM23289.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL365217-3|CAI16606.1|  619|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL132767-2|CAM28320.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL132767-1|CAI22904.1|  619|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL109612-2|CAM27006.1|  594|Homo sapiens EGF-like-domain, multip...    48   2e-05
AL109612-1|CAI18881.1|  619|Homo sapiens EGF-like-domain, multip...    48   2e-05
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.     48   2e-05
AC005327-1|AAC27673.1|  287|Homo sapiens CD97_HUMAN, partial CDS...    48   2e-05
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178...    48   2e-05
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein.     48   2e-05
S83182-1|AAB46909.1|  560|Homo sapiens hyaluronan-binding protei...    48   3e-05
D49742-1|BAA08576.1|  560|Homo sapiens HGF activator like protei...    48   3e-05
BC031412-1|AAH31412.1|  560|Homo sapiens hyaluronan binding prot...    48   3e-05
AY534754-1|AAS16352.1|  560|Homo sapiens hyaluronan binding prot...    48   3e-05
AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein.               48   3e-05
AL390197-1|CAH71108.1|  560|Homo sapiens hyaluronan binding prot...    48   3e-05
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.      48   3e-05
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.                48   3e-05
N00045-1|AAA52764.1|  488|Homo sapiens factor X precursor protein.     48   4e-05
M57285-1|AAA52421.1|  488|Homo sapiens coagulation factor X prot...    48   4e-05
M22613-1|AAA51984.1|  467|Homo sapiens F10 protein.                    48   4e-05
K03194-1|AAA52490.1|  476|Homo sapiens F10 protein.                    48   4e-05
BC046125-1|AAH46125.1|  488|Homo sapiens coagulation factor X pr...    48   4e-05
AL137002-13|CAI41386.1|  488|Homo sapiens coagulation factor X p...    48   4e-05
AL137002-12|CAI41385.1|  332|Homo sapiens coagulation factor X p...    48   4e-05
AL050329-2|CAB99359.1|  399|Homo sapiens protein ( Human DNA seq...    48   4e-05
AF522196-1|AAN45861.1|  870|Homo sapiens scavenger receptor type...    48   4e-05
AF503510-1|AAM19347.1|  488|Homo sapiens coagulation factor X pr...    48   4e-05
AB024433-1|BAD93345.1|  866|Homo sapiens NSR1 protein.                 48   4e-05
AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein.                47   5e-05
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine...    46   9e-05
CR457140-1|CAG33421.1|  448|Homo sapiens FBLN5 protein.                46   9e-05
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en...    46   9e-05
BC022280-1|AAH22280.1|  448|Homo sapiens fibulin 5 protein.            46   9e-05
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en...    46   9e-05
AJ133490-1|CAB38568.1|  448|Homo sapiens fibulin-5 protein.            46   9e-05
AF112152-1|AAD41768.1|  448|Homo sapiens developmental arteries ...    46   9e-05
AF093118-1|AAC62107.1|  448|Homo sapiens UP50 protein.                 46   9e-05
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var...    46   9e-05
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t...    46   1e-04
BC031251-1|AAH31251.1|  375|Homo sapiens EGF-like, fibronectin t...    46   1e-04
AY358903-1|AAQ89262.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AL590226-1|CAH71721.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
AK097549-1|BAC05096.1|  775|Homo sapiens protein ( Homo sapiens ...    46   1e-04
AK092479-1|BAC03900.1|  463|Homo sapiens protein ( Homo sapiens ...    46   1e-04
AF186111-1|AAF01429.1|  273|Homo sapiens NOTCH4-like protein pro...    46   1e-04
D86864-1|BAA24070.1|  830|Homo sapiens acetyl LDL receptor protein.    46   1e-04
D63483-1|BAA09770.1|  830|Homo sapiens KIAA0149 protein.               46   1e-04
BC088371-1|AAH88371.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
BC039735-1|AAH39735.1|  830|Homo sapiens scavenger receptor clas...    46   1e-04
BC035784-1|AAH35784.1|  439|Homo sapiens hypothetical protein FL...    46   1e-04
BC018037-1|AAH18037.1|  379|Homo sapiens WNT inhibitory factor 1...    46   1e-04
BC012377-1|AAH12377.1|  273|Homo sapiens EGF-like-domain, multip...    46   1e-04
AY358902-1|AAQ89261.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AY358901-1|AAQ89260.1|  273|Homo sapiens VEMF protein.                 46   1e-04
AY358344-1|AAQ88710.1|  379|Homo sapiens WIF-1 protein.                46   1e-04
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for...    46   1e-04
AK094759-1|BAC04416.1|  439|Homo sapiens protein ( Homo sapiens ...    46   1e-04
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.     46   1e-04
AF122922-1|AAD25402.1|  379|Homo sapiens Wnt inhibitory factor-1...    46   1e-04
AC092645-2|AAY14854.1|  439|Homo sapiens unknown protein.              46   1e-04
AB177801-1|BAD16737.1|  195|Homo sapiens fibrillin 1 protein.          46   1e-04
AB125649-1|BAD01469.1|  273|Homo sapiens VE-statin protein.            46   1e-04
AB052957-1|BAC15607.1|  803|Homo sapiens soluble form FELE-1 pro...    46   1e-04
AB052949-1|BAC02695.1|  337|Homo sapiens SREC-4 protein.               46   1e-04
AB052948-1|BAC02694.1|  569|Homo sapiens SREC-3 protein.               46   1e-04
AB052947-1|BAC02693.1|  342|Homo sapiens SREC-2 protein.               46   1e-04
AB052946-1|BAC02692.1|  830|Homo sapiens SREC protein.                 46   1e-04
AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein.     46   1e-04
Z97832-1|CAI20187.1|  993|Homo sapiens protein ( Human DNA seque...    45   2e-04
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.       45   2e-04
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.           45   2e-04
M35672-1|AAA51981.1|  291|Homo sapiens F9 protein.                     45   2e-04
M31315-1|AAA70225.1|  612|Homo sapiens F12 protein.                    45   2e-04
M17466-1|AAB59490.1|  615|Homo sapiens coagulation factor XII pr...    45   2e-04
M13147-1|AAA70224.1|  470|Homo sapiens F12 protein.                    45   2e-04
M11723-1|AAA51986.1|  602|Homo sapiens F12 protein.                    45   2e-04
M11309-1|AAA52023.1|  461|Homo sapiens F9 protein.                     45   2e-04
K02402-1|AAB59620.1|  461|Homo sapiens factor IX protein.              45   2e-04

>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
          Length = 1235

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 89.8 bits (213), Expect = 7e-18
 Identities = 41/89 (46%), Positives = 49/89 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG   +TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKYQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 53/89 (59%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG + +T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKYQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C +  G + C C     G
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQCPQGFTG 215



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C CP G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 28/75 (37%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C CP G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCPQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 27/76 (35%), Positives = 44/76 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G   + +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKYQTDMNE 952

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 953  ---CLSEPCKNGGTCS 965



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/87 (32%), Positives = 40/87 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           +   + G C++ G+C   PG      P
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCP 210



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 21/58 (36%), Positives = 28/58 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G    L +
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGMKSSLSI 1226



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79


>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 42/89 (47%), Positives = 50/89 (56%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG  C+TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/89 (42%), Positives = 54/89 (60%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG +C+T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKCQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 39/93 (41%), Positives = 47/93 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C 
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPP-GTRGLLCEENIDDCA 1230

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                    G C D  GG+ C C P   G    G
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            H  C+CPPG  G  CE ++D+C+    CLNGG+C+D +  Y+C C   G+ G RCE ++N
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC-LPGFAGERCEGDIN 1266

Query: 428  ECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            EC  +     G   C      ++C C+ A  G
Sbjct: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C +  G + C C     G
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQCPQGFTG 215



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C CP G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 28/75 (37%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C CP G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCPQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G  C+ +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN- 951

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 952  --ECLSEPCKNGGTCS 965



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE  +  
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCEENID- 1227

Query: 183  DPLCVAGP-CRNNGSCSVPPGG 245
            D  C  GP C N G C    GG
Sbjct: 1228 D--CARGPHCLNGGQCMDRIGG 1247



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
            LC C   +TGR+CET VD C     CLNGG C  A N    + C C   G++GARC+++ 
Sbjct: 1289 LCVCRSAFTGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRC-PPGFSGARCQSS- 1345

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
              C + +   G   C  T  G  C C   +P    +GC
Sbjct: 1346 --CGQVKCRKGE-QCVHTASGPRCFC--PSPRDCESGC 1378



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/87 (32%), Positives = 40/87 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           +   + G C++ G+C   PG      P
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCP 210



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C C     G  CE +  D      C +G +C+ D  G YSC C PG+ G  CE +++ 
Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM-DRIGGYSCRCLPGFAGERCEGDIN- 1266

Query: 183  DPLCVAGPCRNNGS 224
               C++ PC + GS
Sbjct: 1267 --ECLSNPCSSEGS 1278



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 23/77 (29%), Positives = 33/77 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  CE D  +  ++     G+        DY C C   + G +CE  V  
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD- 1306

Query: 183  DPLCVAGPCRNNGSCSV 233
              +C   PC N G+C+V
Sbjct: 1307 --VCPQMPCLNGGTCAV 1321



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C + +TG +CE    D C    C +G  C V     D + C CPPG+ G  C+   
Sbjct: 1288 YLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS- 1345

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                 C    CR    C     G     P  +D
Sbjct: 1346 -----CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +3

Query: 51   DAGDPCASAACRHGARCVEDGRGDY-SCDCPPGYHGTYCEL 170
            D    CAS+ C+HG  C    +  Y SC C P + G+ CEL
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 22/73 (30%), Positives = 29/73 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G  C+      C    CR G +CV    G   C CP       CE       
Sbjct: 1331 CRCPPGFSGARCQ----SSCGQVKCRKGEQCVHTASGP-RCFCPSPRD---CESG----- 1377

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1378 -CASSPCQHGGSC 1389


>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 42/89 (47%), Positives = 50/89 (56%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG  C+TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/89 (42%), Positives = 54/89 (60%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG +C+T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKCQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 39/93 (41%), Positives = 47/93 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C 
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPP-GTRGLLCEENIDDCA 1230

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                    G C D  GG+ C C P   G    G
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            H  C+CPPG  G  CE ++D+C+    CLNGG+C+D +  Y+C C   G+ G RCE ++N
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC-LPGFAGERCEGDIN 1266

Query: 428  ECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            EC  +     G   C      ++C C+ A  G
Sbjct: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C +  G + C C     G
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQCPQGFTG 215



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C CP G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 28/75 (37%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C CP G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCPQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G  C+ +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN- 951

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 952  --ECLSEPCKNGGTCS 965



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE  +  
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCEENID- 1227

Query: 183  DPLCVAGP-CRNNGSCSVPPGG 245
            D  C  GP C N G C    GG
Sbjct: 1228 D--CARGPHCLNGGQCMDRIGG 1247



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
            LC C   +TGR+CET VD C     CLNGG C  A N    + C C   G++GARC+++ 
Sbjct: 1289 LCVCRSAFTGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRC-PPGFSGARCQSS- 1345

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
              C + +   G   C  T  G  C C   +P    +GC
Sbjct: 1346 --CGQVKCRKGE-QCVHTASGPRCFC--PSPRDCESGC 1378



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/87 (32%), Positives = 40/87 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           +   + G C++ G+C   PG      P
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCP 210



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C C     G  CE +  D      C +G +C+ D  G YSC C PG+ G  CE +++ 
Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM-DRIGGYSCRCLPGFAGERCEGDIN- 1266

Query: 183  DPLCVAGPCRNNGS 224
               C++ PC + GS
Sbjct: 1267 --ECLSNPCSSEGS 1278



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 23/77 (29%), Positives = 33/77 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  CE D  +  ++     G+        DY C C   + G +CE  V  
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD- 1306

Query: 183  DPLCVAGPCRNNGSCSV 233
              +C   PC N G+C+V
Sbjct: 1307 --VCPQMPCLNGGTCAV 1321



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C + +TG +CE    D C    C +G  C V     D + C CPPG+ G  C+   
Sbjct: 1288 YLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS- 1345

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                 C    CR    C     G     P  +D
Sbjct: 1346 -----CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +3

Query: 51   DAGDPCASAACRHGARCVEDGRGDY-SCDCPPGYHGTYCEL 170
            D    CAS+ C+HG  C    +  Y SC C P + G+ CEL
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 22/73 (30%), Positives = 29/73 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G  C+      C    CR G +CV    G   C CP       CE       
Sbjct: 1331 CRCPPGFSGARCQ----SSCGQVKCRKGEQCVHTASGP-RCFCPSPRD---CESG----- 1377

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1378 -CASSPCQHGGSC 1389


>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
           (Drosophila) protein.
          Length = 2471

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 42/89 (47%), Positives = 50/89 (56%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG  C+TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/89 (42%), Positives = 54/89 (60%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG +C+T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKCQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 39/93 (41%), Positives = 47/93 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C 
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPP-GTRGLLCEENIDDCA 1230

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                    G C D  GG+ C C P   G    G
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            H  C+CPPG  G  CE ++D+C+    CLNGG+C+D +  Y+C C   G+ G RCE ++N
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC-LPGFAGERCEGDIN 1266

Query: 428  ECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            EC  +     G   C      ++C C+ A  G
Sbjct: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C +  G + C C     G
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQCPQGFTG 215



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C CP G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 28/75 (37%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C CP G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCPQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G  C+ +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN- 951

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 952  --ECLSEPCKNGGTCS 965



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE  +  
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCEENID- 1227

Query: 183  DPLCVAGP-CRNNGSCSVPPGG 245
            D  C  GP C N G C    GG
Sbjct: 1228 D--CARGPHCLNGGQCMDRIGG 1247



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
            LC C   +TGR+CET VD C     CLNGG C  A N    + C C   G++GARC+++ 
Sbjct: 1289 LCVCRSAFTGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRC-PPGFSGARCQSS- 1345

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
              C + +   G   C  T  G  C C   +P    +GC
Sbjct: 1346 --CGQVKCRKGE-QCVHTASGPRCFC--PSPRDCESGC 1378



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/87 (32%), Positives = 40/87 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           +   + G C++ G+C   PG      P
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCP 210



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C C     G  CE +  D      C +G +C+ D  G YSC C PG+ G  CE +++ 
Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM-DRIGGYSCRCLPGFAGERCEGDIN- 1266

Query: 183  DPLCVAGPCRNNGS 224
               C++ PC + GS
Sbjct: 1267 --ECLSNPCSSEGS 1278



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 23/77 (29%), Positives = 33/77 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  CE D  +  ++     G+        DY C C   + G +CE  V  
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD- 1306

Query: 183  DPLCVAGPCRNNGSCSV 233
              +C   PC N G+C+V
Sbjct: 1307 --VCPQMPCLNGGTCAV 1321



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C + +TG +CE    D C    C +G  C V     D + C CPPG+ G  C+   
Sbjct: 1288 YLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS- 1345

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                 C    CR    C     G     P  +D
Sbjct: 1346 -----CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +3

Query: 51   DAGDPCASAACRHGARCVEDGRGDY-SCDCPPGYHGTYCEL 170
            D    CAS+ C+HG  C    +  Y SC C P + G+ CEL
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 22/73 (30%), Positives = 29/73 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G  C+      C    CR G +CV    G   C CP       CE       
Sbjct: 1331 CRCPPGFSGARCQ----SSCGQVKCRKGEQCVHTASGP-RCFCPSPRD---CESG----- 1377

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1378 -CASSPCQHGGSC 1389


>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
          Length = 2471

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 42/89 (47%), Positives = 50/89 (56%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG  C+TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/89 (42%), Positives = 54/89 (60%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG +C+T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKCQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 39/93 (41%), Positives = 47/93 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C 
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPP-GTRGLLCEENIDDCA 1230

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                    G C D  GG+ C C P   G    G
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            H  C+CPPG  G  CE ++D+C+    CLNGG+C+D +  Y+C C   G+ G RCE ++N
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC-LPGFAGERCEGDIN 1266

Query: 428  ECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            EC  +     G   C      ++C C+ A  G
Sbjct: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQC 209



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G  C+ +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN- 951

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 952  --ECLSEPCKNGGTCS 965



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C C  G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCLQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE  +  
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCEENID- 1227

Query: 183  DPLCVAGP-CRNNGSCSVPPGG 245
            D  C  GP C N G C    GG
Sbjct: 1228 D--CARGPHCLNGGQCMDRIGG 1247



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
            LC C   +TGR+CET VD C     CLNGG C  A N    + C C   G++GARC+++ 
Sbjct: 1289 LCVCRSAFTGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRC-PPGFSGARCQSS- 1345

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
              C + +   G   C  T  G  C C   +P    +GC
Sbjct: 1346 --CGQVKCRKGE-QCVHTASGPRCFC--PSPRDCESGC 1378



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 184 NECDIPGHCQHGGTCLNLPG 203



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C C     G  CE +  D      C +G +C+ D  G YSC C PG+ G  CE +++ 
Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM-DRIGGYSCRCLPGFAGERCEGDIN- 1266

Query: 183  DPLCVAGPCRNNGS 224
               C++ PC + GS
Sbjct: 1267 --ECLSNPCSSEGS 1278



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 23/77 (29%), Positives = 33/77 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  CE D  +  ++     G+        DY C C   + G +CE  V  
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD- 1306

Query: 183  DPLCVAGPCRNNGSCSV 233
              +C   PC N G+C+V
Sbjct: 1307 --VCPQMPCLNGGTCAV 1321



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C + +TG +CE    D C    C +G  C V     D + C CPPG+ G  C+   
Sbjct: 1288 YLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS- 1345

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                 C    CR    C     G     P  +D
Sbjct: 1346 -----CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +3

Query: 51   DAGDPCASAACRHGARCVEDGRGDY-SCDCPPGYHGTYCEL 170
            D    CAS+ C+HG  C    +  Y SC C P + G+ CEL
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 22/73 (30%), Positives = 29/73 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G  C+      C    CR G +CV    G   C CP       CE       
Sbjct: 1331 CRCPPGFSGARCQ----SSCGQVKCRKGEQCVHTASGP-RCFCPSPRD---CESG----- 1377

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1378 -CASSPCQHGGSC 1389


>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
          Length = 2471

 Score =  102 bits (245), Expect = 9e-22
 Identities = 41/89 (46%), Positives = 54/89 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ D+D+CS +  CLNG +C+D  N Y C C ATG+TG  CE N++ C+
Sbjct: 518 CLCPPGFTGPVCQIDIDDCS-STPCLNGAKCIDHPNGYECQC-ATGFTGVLCEENIDNCD 575

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D   C HG C D    + C C P   G+
Sbjct: 576 PDP--CHHGQCQDGIDSYTCICNPGYMGA 602



 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 42/89 (47%), Positives = 50/89 (56%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PG+TG  C+TD++EC  +  C NGG C D VN+YTC C A G+ G  CE N+NEC 
Sbjct: 935  CLCLPGFTGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQA-GFDGVHCENNINECT 992

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            E     G G C D    F C C     GS
Sbjct: 993  ESSCFNG-GTCVDGINSFSCLCPVGFTGS 1020



 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/89 (42%), Positives = 54/89 (60%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPPG++G +CE D+D+C  A  C NGG C+D VN ++C C   G+TG +C+T++NEC
Sbjct: 896  MCECPPGFSGMDCEEDIDDCL-ANPCQNGGSCMDGVNTFSCLC-LPGFTGDKCQTDMNEC 953

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
              +    G G C D    + C CQ    G
Sbjct: 954  LSEPCKNG-GTCSDYVNSYTCKCQAGFDG 981



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/97 (41%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAA--CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           P     +CTCP GY G +C  DVDEC+ A +  C + G+CV+    + C+C   GY G R
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC-LKGYAGPR 452

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE ++NEC  D        C D  GGF C C P   G
Sbjct: 453 CEMDINECHSDPCQ-NDATCLDKIGGFTCLCMPGFKG 488



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 39/93 (41%), Positives = 47/93 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C 
Sbjct: 1173 CECVPGYQGVNCEYEVDECQNQP-CQNGGTCIDLVNHFKCSCPP-GTRGLLCEENIDDCA 1230

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                    G C D  GG+ C C P   G    G
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG 1263



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C   +DEC  ++ CLN GRC+D VN Y C+C   G +G  CE N ++C 
Sbjct: 593 CICNPGYMGAICSDQIDECY-SSPCLNDGRCIDLVNGYQCNC-QPGTSGVNCEINFDDCA 650

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+C D    + C C P   G
Sbjct: 651 SNP--CIHGICMDGINRYSCVCSPGFTG 676



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            H  C+CPPG  G  CE ++D+C+    CLNGG+C+D +  Y+C C   G+ G RCE ++N
Sbjct: 1208 HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC-LPGFAGERCEGDIN 1266

Query: 428  ECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            EC  +     G   C      ++C C+ A  G
Sbjct: 1267 ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG 1298



 Score = 83.8 bits (198), Expect = 5e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 1135 CQCPLGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 1192

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    F C+C P T G
Sbjct: 1193 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 1219



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 973  CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 1030

Query: 437  EDRALCGHGVCYDTYGGFVCAC 502
                L   G C D  G + C+C
Sbjct: 1031 SHPCL-NEGTCVDGLGTYRCSC 1051



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/82 (40%), Positives = 44/82 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G NCE D +EC  +  C NGG C + VN Y C C   G+ G  C+ N++EC 
Sbjct: 743 CLCDAGWVGINCEVDKNECL-SNPCQNGGTCDNLVNGYRCTC-KKGFKGYNCQVNIDECA 800

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
            +  L   G C+D   G+ C C
Sbjct: 801 SNPCL-NQGTCFDDISGYTCHC 821



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE ++D+C     C NGG CVD VN Y C C    +TG  C  +V+EC 
Sbjct: 246 CNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECL 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C +  GG+ C C
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVC 326



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G NC+ ++DEC+ +  CLN G C D ++ YTC C    YTG  C+T +  C 
Sbjct: 781  CTCKKGFKGYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLP-YTGKNCQTVLAPCS 838

Query: 437  ----EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                E+ A+C     +++Y    C C P   G   T
Sbjct: 839  PNPCENAAVCKESPNFESY---TCLCAPGWQGQRCT 871



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C +  G + C C     G
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQCPQGFTG 215



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 32/88 (36%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE +++EC  +  C+N G+CVD VN + C C   G+TG  C+ ++++C 
Sbjct: 480 CLCMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLC-PPGFTGPVCQIDIDDCS 537

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D   G+ C C     G
Sbjct: 538 STPCLNG-AKCIDHPNGYECQCATGFTG 564



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 1135 CQCPLGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 1189

Query: 189  LCVAGPCRNNGSC 227
             C   PC+N G+C
Sbjct: 1190 ECQNQPCQNGGTC 1202



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/98 (32%), Positives = 49/98 (50%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
            + +P      C C PG+ G+ C  D+DEC  +  C+N G C +   +Y C+C   G++G 
Sbjct: 849  KESPNFESYTCLCAPGWQGQRCTIDIDECI-SKPCMNHGLCHNTQGSYMCEC-PPGFSGM 906

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             CE ++++C  +    G G C D    F C C P   G
Sbjct: 907  DCEEDIDDCLANPCQNG-GSCMDGVNTFSCLCLPGFTG 943



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-PQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPATPGST 526
               + G G C  T    F C C P   GST
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPGFEGST 256



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+ C  D+DEC+ +  C  G  C++ VN + C C   G     C + VNEC 
Sbjct: 668 CVCSPGFTGQRCNIDIDECA-SNPCRKGATCINGVNGFRCIC-PEGPHHPSCYSQVNECL 725

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG C     G+ C C     G
Sbjct: 726 SNP--CIHGNCTGGLSGYKCLCDAGWVG 751



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPP +TG+ C  DVDEC     AC NGG C +    Y C C   G++G  C  N+++C
Sbjct: 284 CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVC-VNGWSGDDCSENIDDC 342

Query: 434 EEDRALCGHG-VCYDTYGGFVCACQPATPG 520
               A C  G  C D    F C C     G
Sbjct: 343 A--FASCTPGSTCIDRVASFSCMCPEGKAG 370



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 30/75 (40%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G  CE+D  + C S  C++ A C+ D  G ++C C PG+ G +CELE++ 
Sbjct: 440 FHCECLKGYAGPRCEMDINE-CHSDPCQNDATCL-DKIGGFTCLCMPGFKGVHCELEIN- 496

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC NNG C
Sbjct: 497 --ECQSNPCVNNGQC 509



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C CP G+TG+ C++    C+  + C+NGG C    +  + C+C   G+ G+ CE N+++C
Sbjct: 207 CQCPQGFTGQYCDSLYVPCA-PSPCVNGGTCRQTGDFTFECNCLP-GFEGSTCERNIDDC 264

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
              R   G GVC D    + C C P   G   T
Sbjct: 265 PNHRCQNG-GVCVDGVNTYNCRCPPQWTGQFCT 296



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  C +D  D C S  C +   C  + +G Y C+CPPG+ G  CE ++  
Sbjct: 857  YTCLCAPGWQGQRCTIDI-DECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDID- 913

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
            D  C+A PC+N GSC    G +T+S
Sbjct: 914  D--CLANPCQNGGSCM--DGVNTFS 934



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 28/75 (37%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C CP G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCPQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
            Y CHC   YTG NC+     PC+   C + A C E    + Y+C C PG+ G  C +++ 
Sbjct: 817  YTCHCVLPYTGKNCQTVLA-PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875

Query: 180  LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                C++ PC N+G C    G      P
Sbjct: 876  ---ECISKPCMNHGLCHNTQGSYMCECP 900



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE D  D C +  C++G  C+ DG   +SC C PG+ G  C+ +++ 
Sbjct: 895  YMCECPPGFSGMDCEEDIDD-CLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMN- 951

Query: 183  DPLCVAGPCRNNGSCS 230
               C++ PC+N G+CS
Sbjct: 952  --ECLSEPCKNGGTCS 965



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/75 (40%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C+C    +G NCE++  D CAS  C HG  C+ DG   YSC C PG+ G  C +++  
Sbjct: 629 YQCNCQPGTSGVNCEINFDD-CASNPCIHGI-CM-DGINRYSCVCSPGFTGQRCNIDID- 684

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR   +C
Sbjct: 685 --ECASNPCRKGATC 697



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/82 (39%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE  +  
Sbjct: 1171 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCEENID- 1227

Query: 183  DPLCVAGP-CRNNGSCSVPPGG 245
            D  C  GP C N G C    GG
Sbjct: 1228 D--CARGPHCLNGGQCMDRIGG 1247



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 29/81 (35%), Positives = 45/81 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC+C   + G+ CE +  D C +  C++G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 244 FECNCLPGFEGSTCERNIDD-CPNHRCQNGGVCV-DGVNTYNCRCPPQWTGQFCTEDVD- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           + L     C+N G+C+   GG
Sbjct: 301 ECLLQPNACQNGGTCANRNGG 321



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  CE +  D C    C HG +C +DG   Y+C C PGY G  C  ++  
Sbjct: 554 YECQCATGFTGVLCEENI-DNCDPDPCHHG-QC-QDGIDSYTCICNPGYMGAICSDQID- 609

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G C
Sbjct: 610 --ECYSSPCLNDGRC 622



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 43/75 (57%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 971  YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 1027

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G+C
Sbjct: 1028 --ECSSHPCLNEGTC 1040



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C A + G NCEVD  + C S  C++G  C     G Y C C  G+ G  C  +V++
Sbjct: 741 YKCLCDAGWVGINCEVDKNE-CLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNC--QVNI 796

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC N G+C
Sbjct: 797 DE-CASNPCLNQGTC 810



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 1009 FSCLCPVGFTGSFCLHEINE-CSSHPCLNEGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 1065

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC+N G+C
Sbjct: 1066 --LCSRSPCKNKGTC 1078



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
            LC C   +TGR+CET VD C     CLNGG C  A N    + C C   G++GARC+++ 
Sbjct: 1289 LCVCRSAFTGRHCETFVDVCP-QMPCLNGGTCAVASNMPDGFICRC-PPGFSGARCQSS- 1345

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
              C + +   G   C  T  G  C C   +P    +GC
Sbjct: 1346 --CGQVKCRKGE-QCVHTASGPRCFC--PSPRDCESGC 1378



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/76 (38%), Positives = 42/76 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  +TG  C +D  D CAS  CR GA C+ +G   + C CP G H   C  +V+ 
Sbjct: 666 YSCVCSPGFTGQRCNIDI-DECASNPCRKGATCI-NGVNGFRCICPEGPHHPSCYSQVN- 722

Query: 183 DPLCVAGPCRNNGSCS 230
              C++ PC  +G+C+
Sbjct: 723 --ECLSNPC-IHGNCT 735



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA---ACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G +C  D  D CA A    C H  +CV    G + C+C  GY G  CE++
Sbjct: 399 YICTCPQGYKGADCTEDV-DECAMANSNPCEHAGKCVNTD-GAFHCECLKGYAGPRCEMD 456

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDT 251
           ++    C + PC+N+ +C    GG T
Sbjct: 457 IN---ECHSDPCQNDATCLDKIGGFT 479



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/85 (34%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG  C++D  D C+S  C +GA+C++   G Y C C  G+ G  CE  +  
Sbjct: 516 FQCLCPPGFTGPVCQIDIDD-CSSTPCLNGAKCIDHPNG-YECQCATGFTGVLCEENID- 572

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC ++G C    G D+Y+
Sbjct: 573 --NCDPDPC-HHGQCQ--DGIDSYT 592



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 29/85 (34%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C PG+ G+ CE  +  
Sbjct: 205 YQCQCPQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID- 262

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G C    G +TY+
Sbjct: 263 D--CPNHRCQNGGVC--VDGVNTYN 283



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/84 (33%), Positives = 39/84 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G++C  +  D CA A+C  G+ C+ D    +SC CP G  G  C     L
Sbjct: 322 YGCVCVNGWSGDDCSENIDD-CAFASCTPGSTCI-DRVASFSCMCPEGKAGLLCH----L 375

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
           D  C++ PC     C   P    Y
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQY 399



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP GYTG+NC+T V+ CS  + C N G CV       C C  +G+ GA C+     C+
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLC-PSGWAGAYCDVPNVSCD 1106

Query: 437  EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
               +        LC H GVC +      C C     GS
Sbjct: 1107 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS 1144



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/87 (32%), Positives = 40/87 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           +   + G C++ G+C   PG      P
Sbjct: 184 NECDIPGHCQHGGTCLNLPGSYQCQCP 210



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/81 (32%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +CE++  + C S  C +  +CV D    + C CPPG+ G  C++++  
Sbjct: 478 FTCLCMPGFKGVHCELEINE-CQSNPCVNNGQCV-DKVNRFQCLCPPGFTGPVCQIDID- 534

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C + PC N   C   P G
Sbjct: 535 D--CSSTPCLNGAKCIDHPNG 553



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C     G  C +D  D C S  C  GA C  +   G Y C CP GY G  C  +V 
Sbjct: 360 FSCMCPEGKAGLLCHLD--DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD 417

Query: 180 LDPLCVAGPCRNNGSC 227
              +  + PC + G C
Sbjct: 418 ECAMANSNPCEHAGKC 433



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
           Y C C   Y G  C  D  D C S+ C +  RC++   G Y C+C PG  G  CE+   +
Sbjct: 591 YTCICNPGYMGAICS-DQIDECYSSPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDD 648

Query: 174 VSLDPLCVAGPCR---NNGSCSVPPG 242
            + +P C+ G C    N  SC   PG
Sbjct: 649 CASNP-CIHGICMDGINRYSCVCSPG 673



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 25/74 (33%), Positives = 38/74 (51%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C C     G  CE +  D      C +G +C+ D  G YSC C PG+ G  CE +++ 
Sbjct: 1209 FKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCM-DRIGGYSCRCLPGFAGERCEGDIN- 1266

Query: 183  DPLCVAGPCRNNGS 224
               C++ PC + GS
Sbjct: 1267 --ECLSNPCSSEGS 1278



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVN-NYTCDCTATGYTGARCETNVNE 430
           C CP G  G  C  D D C  +  C  G  C  + +N  Y C C   GY GA C  +V+E
Sbjct: 362 CMCPEGKAGLLCHLD-DACI-SNPCHKGALCDTNPLNGQYICTC-PQGYKGADCTEDVDE 418

Query: 431 CE-EDRALCGH-GVCYDTYGGFVCAC 502
           C   +   C H G C +T G F C C
Sbjct: 419 CAMANSNPCEHAGKCVNTDGAFHCEC 444



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 1086 QCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPLGYTGS 1144

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            YCE +  LD  C + PC++  +CS   GG
Sbjct: 1145 YCEEQ--LDE-CASNPCQHGATCSDFIGG 1170



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+    + C+ + C++   CV+  + +  C CP G+ G YC++  VS
Sbjct: 1047 YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KAESQCLCPSGWAGAYCDVPNVS 1104

Query: 180  LD 185
             D
Sbjct: 1105 CD 1106



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 23/77 (29%), Positives = 33/77 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G  CE D  +  ++     G+        DY C C   + G +CE  V  
Sbjct: 1248 YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVD- 1306

Query: 183  DPLCVAGPCRNNGSCSV 233
              +C   PC N G+C+V
Sbjct: 1307 --VCPQMPCLNGGTCAV 1321



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 147

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 148 CLSHP--CANGSTCTTVANQFSCKC 170



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C + +TG +CE    D C    C +G  C V     D + C CPPG+ G  C+   
Sbjct: 1288 YLCVCRSAFTGRHCETFV-DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS- 1345

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                 C    CR    C     G     P  +D
Sbjct: 1346 -----CGQVKCRKGEQCVHTASGPRCFCPSPRD 1373



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/75 (30%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C       +C     + C S  C HG  C   G   Y C C  G+ G  CE++ + 
Sbjct: 704 FRCICPEGPHHPSCYSQVNE-CLSNPCIHG-NCT-GGLSGYKCLCDAGWVGINCEVDKN- 759

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC+N G+C
Sbjct: 760 --ECLSNPCQNGGTC 772



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C  ++TG  C  D  D C     AC++G  C  +  G Y C C  G+ G  C   +
Sbjct: 282 YNCRCPPQWTGQFCTEDV-DECLLQPNACQNGGTCA-NRNGGYGCVCVNGWSGDDCSENI 339

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C    +C
Sbjct: 340 D-D--CAFASCTPGSTC 353



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +3

Query: 51   DAGDPCASAACRHGARCVEDGRGDY-SCDCPPGYHGTYCEL 170
            D    CAS+ C+HG  C    +  Y SC C P + G+ CEL
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 79



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 22/73 (30%), Positives = 29/73 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G  C+      C    CR G +CV    G   C CP       CE       
Sbjct: 1331 CRCPPGFSGARCQ----SSCGQVKCRKGEQCVHTASGP-RCFCPSPRD---CESG----- 1377

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1378 -CASSPCQHGGSC 1389


>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
            protein.
          Length = 3574

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 1213 RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1270

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1271 NECSSSPCL-NKGICVDGVAGYRCTC 1295



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1330 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1387

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1388 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1415



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1293 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1350

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1351 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1378



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1255 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1309

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1310 ECQSNPCLNNAVCEDQVGGFLCKCP 1334



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1291 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1347

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1348 --ECLSQPCKNGATC 1360



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 1215 YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1271

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1272 --ECSSSPCLNKGIC 1284



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1331 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1385

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1386 ECQSNPCRNQATC 1398



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1367 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1423



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1259

Query: 509  ATPG 520
               G
Sbjct: 1260 GYTG 1263



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/56 (50%), Positives = 33/56 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C+CP G+ GR CE  +  C     CLNGGRCV     Y CDC   G+TG+RC T V
Sbjct: 3491 CSCPEGWMGRLCEEPI--C--ILPCLNGGRCVAP---YQCDC-PPGWTGSRCHTAV 3538



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/73 (34%), Positives = 30/73 (41%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE    +P     C +G RCV      Y CDCPPG+ G+ C   V   P
Sbjct: 3491 CSCPEGWMGRLCE----EPICILPCLNGGRCV----APYQCDCPPGWTGSRCHTAVCQSP 3542

Query: 189  LCVAGPCRNNGSC 227
                G C     C
Sbjct: 3543 CLNGGKCVRPNRC 3555



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 23/52 (44%), Positives = 29/52 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C CPPG+TG  C T V  C   + CLNGG+C   V    C C ++ +TG  C
Sbjct: 3523 CDCPPGWTGSRCHTAV--CQ--SPCLNGGKC---VRPNRCHCLSS-WTGHNC 3566



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            C++G  C        +C CP G+ G  CE     +P+C+  PC N G C  P
Sbjct: 3479 CQNGGICQRPN----ACSCPEGWMGRLCE-----EPICIL-PCLNGGRCVAP 3520



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            DVDEC+  + C     C++   +Y C C  + YTG
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPS-YTG 1781



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y+C C   +TG+ C       C S  C +G +CV   R    C C   + G  C
Sbjct: 3521 YQCDCPPGWTGSRCHTAV---CQS-PCLNGGKCVRPNR----CHCLSSWTGHNC 3566


>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 1190 RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1247

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1248 NECSSSPCL-NKGICVDGVAGYRCTC 1272



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1307 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1364

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1365 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1392



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1270 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1327

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1328 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1355



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1232 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1286

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1287 ECQSNPCLNNAVCEDQVGGFLCKCP 1311



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1268 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1324

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1325 --ECLSQPCKNGATC 1337



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 1192 YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1248

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1249 --ECSSSPCLNKGIC 1261



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1308 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1362

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1363 ECQSNPCRNQATC 1375



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1344 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1400



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1236

Query: 509  ATPG 520
               G
Sbjct: 1237 GYTG 1240



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/56 (50%), Positives = 33/56 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C+CP G+ GR CE  +  C     CLNGGRCV     Y CDC   G+TG+RC T V
Sbjct: 3465 CSCPEGWMGRLCEEPI--C--ILPCLNGGRCVAP---YQCDC-PPGWTGSRCHTAV 3512



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/73 (34%), Positives = 30/73 (41%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE    +P     C +G RCV      Y CDCPPG+ G+ C   V   P
Sbjct: 3465 CSCPEGWMGRLCE----EPICILPCLNGGRCV----APYQCDCPPGWTGSRCHTAVCQSP 3516

Query: 189  LCVAGPCRNNGSC 227
                G C     C
Sbjct: 3517 CLNGGKCVRPNRC 3529



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 23/52 (44%), Positives = 29/52 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C CPPG+TG  C T V  C   + CLNGG+C   V    C C ++ +TG  C
Sbjct: 3497 CDCPPGWTGSRCHTAV--CQ--SPCLNGGKC---VRPNRCHCLSS-WTGHNC 3540



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            C++G  C        +C CP G+ G  CE     +P+C+  PC N G C  P
Sbjct: 3453 CQNGGICQRPN----ACSCPEGWMGRLCE-----EPICIL-PCLNGGRCVAP 3494



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 13/35 (37%), Positives = 18/35 (51%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            DVDEC+  + C     C++   +Y C C    YTG
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPP-YTG 1755



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y+C C   +TG+ C       C S  C +G +CV   R    C C   + G  C
Sbjct: 3495 YQCDCPPGWTGSRCHTAV---CQS-PCLNGGKCVRPNR----CHCLSSWTGHNC 3540


>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 1190 RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1247

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1248 NECSSSPCL-NKGICVDGVAGYRCTC 1272



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1307 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1364

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1365 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1392



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1270 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1327

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1328 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1355



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1232 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1286

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1287 ECQSNPCLNNAVCEDQVGGFLCKCP 1311



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1268 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1324

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1325 --ECLSQPCKNGATC 1337



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 1192 YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1248

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1249 --ECSSSPCLNKGIC 1261



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1308 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1362

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1363 ECQSNPCRNQATC 1375



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1344 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1400



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1236

Query: 509  ATPG 520
               G
Sbjct: 1237 GYTG 1240



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/56 (50%), Positives = 33/56 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C+CP G+ GR CE  +  C     CLNGGRCV     Y CDC   G+TG+RC T V
Sbjct: 3465 CSCPEGWMGRLCEEPI--C--ILPCLNGGRCVAP---YQCDC-PPGWTGSRCHTAV 3512



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/73 (34%), Positives = 30/73 (41%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE    +P     C +G RCV      Y CDCPPG+ G+ C   V   P
Sbjct: 3465 CSCPEGWMGRLCE----EPICILPCLNGGRCV----APYQCDCPPGWTGSRCHTAVCQSP 3516

Query: 189  LCVAGPCRNNGSC 227
                G C     C
Sbjct: 3517 CLNGGKCVRPNRC 3529



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 23/52 (44%), Positives = 29/52 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C CPPG+TG  C T V  C   + CLNGG+C   V    C C ++ +TG  C
Sbjct: 3497 CDCPPGWTGSRCHTAV--CQ--SPCLNGGKC---VRPNRCHCLSS-WTGHNC 3540



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            C++G  C        +C CP G+ G  CE     +P+C+  PC N G C  P
Sbjct: 3453 CQNGGICQRPN----ACSCPEGWMGRLCE-----EPICIL-PCLNGGRCVAP 3494



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 13/35 (37%), Positives = 18/35 (51%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            DVDEC+  + C     C++   +Y C C    YTG
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPP-YTG 1755



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y+C C   +TG+ C       C S  C +G +CV   R    C C   + G  C
Sbjct: 3495 YQCDCPPGWTGSRCHTAV---CQS-PCLNGGKCVRPNR----CHCLSSWTGHNC 3540


>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 1190 RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1247

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1248 NECSSSPCL-NKGICVDGVAGYRCTC 1272



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1307 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1364

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1365 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1392



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1270 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1327

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1328 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1355



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1232 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1286

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1287 ECQSNPCLNNAVCEDQVGGFLCKCP 1311



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1268 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1324

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1325 --ECLSQPCKNGATC 1337



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 1192 YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1248

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1249 --ECSSSPCLNKGIC 1261



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1308 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1362

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1363 ECQSNPCRNQATC 1375



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1344 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1400



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1236

Query: 509  ATPG 520
               G
Sbjct: 1237 GYTG 1240



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/56 (50%), Positives = 33/56 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C+CP G+ GR CE  +  C     CLNGGRCV     Y CDC   G+TG+RC T V
Sbjct: 3465 CSCPEGWMGRLCEEPI--C--ILPCLNGGRCVAP---YQCDC-PPGWTGSRCHTAV 3512



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/73 (34%), Positives = 30/73 (41%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE    +P     C +G RCV      Y CDCPPG+ G+ C   V   P
Sbjct: 3465 CSCPEGWMGRLCE----EPICILPCLNGGRCV----APYQCDCPPGWTGSRCHTAVCQSP 3516

Query: 189  LCVAGPCRNNGSC 227
                G C     C
Sbjct: 3517 CLNGGKCVRPNRC 3529



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 23/52 (44%), Positives = 29/52 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C CPPG+TG  C T V  C   + CLNGG+C   V    C C ++ +TG  C
Sbjct: 3497 CDCPPGWTGSRCHTAV--CQ--SPCLNGGKC---VRPNRCHCLSS-WTGHNC 3540



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            C++G  C        +C CP G+ G  CE     +P+C+  PC N G C  P
Sbjct: 3453 CQNGGICQRPN----ACSCPEGWMGRLCE-----EPICIL-PCLNGGRCVAP 3494



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 13/35 (37%), Positives = 18/35 (51%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            DVDEC+  + C     C++   +Y C C    YTG
Sbjct: 1722 DVDECAVGSDCSEHASCLNVDGSYICSCVPP-YTG 1755



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y+C C   +TG+ C       C S  C +G +CV   R    C C   + G  C
Sbjct: 3495 YQCDCPPGWTGSRCHTAV---CQS-PCLNGGKCVRPNR----CHCLSSWTGHNC 3540


>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
            FLJ14964 fis, clone PLACE4000581, moderately similar to
            FIBROPELLIN I PRECURSOR. ).
          Length = 1316

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 980  RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1037

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1038 NECSSSPCL-NKGICVDGVAGYRCTC 1062



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1097 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1154

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1155 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1182



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1060 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1117

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1118 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1145



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1022 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1076

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1077 ECQSNPCLNNAVCEDQVGGFLCKCP 1101



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1058 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1114

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1115 --ECLSQPCKNGATC 1127



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 982  YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1038

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1039 --ECSSSPCLNKGIC 1051



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1098 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1152

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1153 ECQSNPCRNQATC 1165



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1134 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1190



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 969  CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1026

Query: 509  ATPG 520
               G
Sbjct: 1027 GYTG 1030


>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
          Length = 3574

 Score = 99.5 bits (237), Expect = 9e-21
 Identities = 43/86 (50%), Positives = 51/86 (59%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP GYTG  CETD+DECS    CLN G C D V  + C+C  +GYTG RCE N+
Sbjct: 1213 RGYVCLCPLGYTGLKCETDIDECS-PLPCLNNGVCKDLVGEFICEC-PSGYTGQRCEENI 1270

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC     L   G+C D   G+ C C
Sbjct: 1271 NECSSSPCL-NKGICVDGVAGYRCTC 1295



 Score = 87.8 bits (208), Expect = 3e-17
 Identities = 37/89 (41%), Positives = 48/89 (53%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC CPPG+ G  C  +VDEC  +  C NG  C D  N++ C C A G+TG+ CE N+NEC
Sbjct: 1330 LCKCPPGFLGTRCGKNVDECL-SQPCKNGATCKDGANSFRCLC-AAGFTGSHCELNINEC 1387

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +        C D    + C CQP   G
Sbjct: 1388 QSNPCR-NQATCVDELNSYSCKCQPGFSG 1415



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 35/89 (39%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC  G+ G +CET+V+EC  +  CLN   C D V  + C C   G+ G RC  NV+EC 
Sbjct: 1293 CTCVKGFVGLHCETEVNECQ-SNPCLNNAVCEDQVGGFLCKC-PPGFLGTRCGKNVDECL 1350

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D    F C C     GS
Sbjct: 1351 SQPCKNG-ATCKDGANSFRCLCAAGFTGS 1378



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/85 (37%), Positives = 42/85 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C + YTG  CE +  + C+S+ C +   CV DG   Y C C  G+ G +CE EV+   
Sbjct: 1255 CECPSGYTGQRCEENINE-CSSSPCLNKGICV-DGVAGYRCTCVKGFVGLHCETEVN--- 1309

Query: 189  LCVAGPCRNNGSCSVPPGGDTYSAP 263
             C + PC NN  C    GG     P
Sbjct: 1310 ECQSNPCLNNAVCEDQVGGFLCKCP 1334



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +CE +  + C S  C + A C ED  G + C CPPG+ GT C   V  
Sbjct: 1291 YRCTCVKGFVGLHCETEVNE-CQSNPCLNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVD- 1347

Query: 183  DPLCVAGPCRNNGSC 227
               C++ PC+N  +C
Sbjct: 1348 --ECLSQPCKNGATC 1360



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG  CE D  D C+   C +   C +D  G++ C+CP GY G  CE  ++ 
Sbjct: 1215 YVCLCPLGYTGLKCETDI-DECSPLPCLNNGVC-KDLVGEFICECPSGYTGQRCEENIN- 1271

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 1272 --ECSSSPCLNKGIC 1284



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  C  +  D C S  C++GA C +DG   + C C  G+ G++CEL ++   
Sbjct: 1331 CKCPPGFLGTRCGKNV-DECLSQPCKNGATC-KDGANSFRCLCAAGFTGSHCELNIN--- 1385

Query: 189  LCVAGPCRNNGSC 227
             C + PCRN  +C
Sbjct: 1386 ECQSNPCRNQATC 1398



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 25/59 (42%), Positives = 36/59 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C A +TG++CE++  + C S  CR+ A CV++    YSC C PG+ G  CE E S
Sbjct: 1367 FRCLCAAGFTGSHCELNINE-CQSNPCRNQATCVDE-LNSYSCKCQPGFSGKRCETEQS 1423



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 26/64 (40%), Positives = 32/64 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            C N G C      Y C C   GYTG +CET+++EC     L  +GVC D  G F+C C  
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPL-GYTGLKCETDIDECSPLPCL-NNGVCKDLVGEFICECPS 1259

Query: 509  ATPG 520
               G
Sbjct: 1260 GYTG 1263



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/56 (50%), Positives = 33/56 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C+CP G+ GR CE  +  C     CLNGGRCV     Y CDC   G+TG+RC T V
Sbjct: 3491 CSCPEGWMGRLCEEPI--C--ILPCLNGGRCVAP---YQCDC-PPGWTGSRCHTAV 3538



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/73 (34%), Positives = 30/73 (41%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE    +P     C +G RCV      Y CDCPPG+ G+ C   V   P
Sbjct: 3491 CSCPEGWMGRLCE----EPICILPCLNGGRCV----APYQCDCPPGWTGSRCHTAVCQSP 3542

Query: 189  LCVAGPCRNNGSC 227
                G C     C
Sbjct: 3543 CLNGGKCVRPNRC 3555



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 23/52 (44%), Positives = 29/52 (55%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C CPPG+TG  C T V  C   + CLNGG+C   V    C C ++ +TG  C
Sbjct: 3523 CDCPPGWTGSRCHTAV--CQ--SPCLNGGKC---VRPNRCHCLSS-WTGHNC 3566



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            C++G  C        +C CP G+ G  CE     +P+C+  PC N G C  P
Sbjct: 3479 CQNGGICQRPN----ACSCPEGWMGRLCE-----EPICIL-PCLNGGRCVAP 3520



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            DVDEC+  + C     C++   +Y C C  + YTG
Sbjct: 1748 DVDECAVGSDCSEHASCLNVDGSYICSCVPS-YTG 1781



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y+C C   +TG+ C       C S  C +G +CV   R    C C   + G  C
Sbjct: 3521 YQCDCPPGWTGSRCHTAV---CQS-PCLNGGKCVRPNR----CHCLSSWTGHNC 3566


>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
           variant protein.
          Length = 2067

 Score = 98.3 bits (234), Expect = 2e-20
 Identities = 41/88 (46%), Positives = 53/88 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+TG  C+ DVDEC+ +  C NG +C+D  N YTC CT  GYTG  CE +++EC+
Sbjct: 26  CECPTGFTGHLCQYDVDECA-STPCKNGAKCLDGPNTYTCVCT-EGYTGTHCEVDIDECD 83

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D   C +G C D    F C C+P   G
Sbjct: 84  PDP--CHYGSCKDGVATFTCLCRPGYTG 109



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/89 (43%), Positives = 49/89 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C  ++DEC+G   C NGG C D +N +TC C   GY    C + VNEC 
Sbjct: 176 CACEPGYTGSMCNINIDECAG-NPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECN 233

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +   C HG C D+  G+ C C P   G+
Sbjct: 234 SNP--CVHGACRDSLNGYKCDCDPGWSGT 260



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 40/89 (44%), Positives = 52/89 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG +CET+++ECS +  C +GG C D  N Y C C   G TG  CE N+++C 
Sbjct: 101 CLCRPGYTGHHCETNINECS-SQPCRHGGTCQDRDNAYLCFC-LKGTTGPNCEINLDDCA 158

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
              + C  G C D   G+ CAC+P   GS
Sbjct: 159 S--SPCDSGTCLDKIDGYECACEPGYTGS 185



 Score = 90.2 bits (214), Expect = 5e-18
 Identities = 39/97 (40%), Positives = 58/97 (59%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP G++G +CE +  +C+  ++C NGG CVD +N++TC C   G+TG+ C+ +VNEC+
Sbjct: 481 CTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLC-PPGFTGSYCQHDVNECD 538

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRV 547
               L G G C D  G + C C     G T   C+ +
Sbjct: 539 SQPCLHG-GTCQDGCGSYRCTC---PQGYTGPNCQNL 571



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 38/89 (42%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GY+GRNCETD+D+C     C NGG C D +N   CDC   G+ G  CE ++NEC 
Sbjct: 405 CHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDC-LPGFRGTFCEEDINECA 462

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
            D   C +G  C D    + C C     G
Sbjct: 463 SDP--CRNGANCTDCVDSYTCTCPAGFSG 489



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 35/90 (38%), Positives = 50/90 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G NC+ + +EC  +  C+NGG C D  + Y C C   G++G  C+TN+NEC 
Sbjct: 251 CDCDPGWSGTNCDINNNECE-SNPCVNGGTCKDMTSGYVCTC-REGFSGPNCQTNINECA 308

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +  L   G C D   G+ C C     G+T
Sbjct: 309 SNPCL-NQGTCIDDVAGYKCNCLLPYTGAT 337



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 40/89 (44%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG +CE D+DEC     C + G C D V  +TC C   GYTG  CETN+NEC 
Sbjct: 64  CVCTEGYTGTHCEVDIDECD-PDPC-HYGSCKDGVATFTCLC-RPGYTGHHCETNINECS 120

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C D    ++C C   T G
Sbjct: 121 SQP--CRHGGTCQDRDNAYLCFCLKGTTG 147



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 35/88 (39%), Positives = 47/88 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+TG  C+ DV+EC  +  CL+GG C D   +Y C C   GYTG  C+  V+ C+
Sbjct: 519 CLCPPGFTGSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTC-PQGYTGPNCQNLVHWCD 576

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C+ T+  + C C     G
Sbjct: 577 SSPCKNG-GKCWQTHTQYRCECPSGWTG 603



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGR-CVDAVNNYTCDCTATGYTGARCETNVNEC 433
            CTCPPG+ G  CE DV+EC        G + CV  VN++ C+C A G+TG RCE+ +N C
Sbjct: 765  CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA-GHTGRRCESVINGC 823

Query: 434  EEDRALCGH--GVCYDTYGGFVCACQPATPGST 526
            +      G    V  +T  GF+C C     G+T
Sbjct: 824  KGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 856



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y CHC A Y+G NCE D  D C    C +G  C  DG     CDC PG+ GT+CE +++ 
Sbjct: 403 YRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCT-DGINTAFCDCLPGFRGTFCEEDIN- 459

Query: 183 DPLCVAGPCRNNGSCS 230
              C + PCRN  +C+
Sbjct: 460 --ECASDPCRNGANCT 473



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/88 (40%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG  CE  VDECS  + C NG  C D +  Y+C C A GY G  C   ++EC 
Sbjct: 643 CRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVA-GYHGVNCSEEIDECL 700

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    + C+C   T G
Sbjct: 701 SHPCQNG-GTCLDLPNTYKCSCPRGTQG 727



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 36/87 (41%), Positives = 47/87 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A YTG+ CE D  D C+ + C++GA C  D  G YSC C  GYHG  C  E+  
Sbjct: 641 HHCRCQAGYTGSYCE-DLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVNCSEEID- 697

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C++ PC+N G+C   P     S P
Sbjct: 698 --ECLSHPCQNGGTCLDLPNTYKCSCP 722



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G TG NCE ++D+C  A++  + G C+D ++ Y C C   GYTG+ C  N++EC
Sbjct: 138 LCFCLKGTTGPNCEINLDDC--ASSPCDSGTCLDKIDGYECAC-EPGYTGSMCNINIDEC 194

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
             +    G G C D   GF C C
Sbjct: 195 AGNPCHNG-GTCEDGINGFTCRC 216



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +CTC  G++G NC+T+++EC+ +  CLN G C+D V  Y C+C    YTGA CE  +  C
Sbjct: 288 VCTCREGFSGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNCLLP-YTGATCEVVLAPC 345

Query: 434 EEDRALCGHGVC--YDTYGGFVCACQPATPGST 526
                  G G C   + Y  F C C     G T
Sbjct: 346 APSPCRNG-GECRQSEDYESFSCVCPTGWQGQT 377



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-DGRGDYSCDCPPGYHGTYCELEVS 179
           Y+C+C   YTG  CEV    PCA + CR+G  C + +    +SC CP G+ G  CE++++
Sbjct: 325 YKCNCLLPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 383

Query: 180 LDPLCVAGPCRNNGSCSVPPGG 245
               CV  PCR+  SC    GG
Sbjct: 384 ---ECVLSPCRHGASCQNTHGG 402



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/89 (35%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G+ CE D++EC   + C +G  C +    Y C C A GY+G  CET++++C 
Sbjct: 367 CVCPTGWQGQTCEVDINECV-LSPCRHGASCQNTHGGYRCHCQA-GYSGRNCETDIDDCR 424

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +    G G C D      C C P   G+
Sbjct: 425 PNPCHNG-GSCTDGINTAFCDCLPGFRGT 452



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 39/107 (36%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-------SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+CP G  G +CE +VD+C       S +  C N G CVD V  Y+C C   G+ G RCE
Sbjct: 719  CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC-PPGFVGERCE 777

Query: 416  TNVNECEEDRA-LCGHGVCYDTYGGFVCACQPATPG----STATGCR 541
             +VNEC  +     G   C      F C C+    G    S   GC+
Sbjct: 778  GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 824



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/75 (41%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG+ C+ D  D CAS  C++GA+C+ DG   Y+C C  GY GT+CE+++  
Sbjct: 24  FQCECPTGFTGHLCQYDV-DECASTPCKNGAKCL-DGPNTYTCVCTEGYTGTHCEVDID- 80

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC + GSC
Sbjct: 81  --ECDPDPC-HYGSC 92



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 31/76 (40%), Positives = 40/76 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEVD  + C  + CRHGA C ++  G Y C C  GY G  CE ++  
Sbjct: 365 FSCVCPTGWQGQTCEVDINE-CVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNCETDID- 421

Query: 183 DPLCVAGPCRNNGSCS 230
           D  C   PC N GSC+
Sbjct: 422 D--CRPNPCHNGGSCT 435



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 37/91 (40%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
           C CP G+TG  C+     C  AA          C +GG CVDA N + C C A GYTG+ 
Sbjct: 595 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQA-GYTGSY 653

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CE  V+EC       G   C D  GG+ C C
Sbjct: 654 CEDLVDECSPSPCQNG-ATCTDYLGGYSCKC 683



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C CT  YTG +CEVD  D C    C +G+ C +DG   ++C C PGY G +CE  ++ 
Sbjct: 62  YTCVCTEGYTGTHCEVDI-DECDPDPCHYGS-C-KDGVATFTCLCRPGYTGHHCETNIN- 117

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G+C
Sbjct: 118 --ECSSQPCRHGGTC 130



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 37/86 (43%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           YEC C   YTG+ C ++  D CA   C +G  C EDG   ++C CP GYH   C  EV  
Sbjct: 174 YECACEPGYTGSMCNINI-DECAGNPCHNGGTC-EDGINGFTCRCPEGYHDPTCLSEVNE 231

Query: 177 -SLDPLCVAGPCRN--NG-SCSVPPG 242
            + +P CV G CR+  NG  C   PG
Sbjct: 232 CNSNP-CVHGACRDSLNGYKCDCDPG 256



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           Y C C A Y G NC  +  D C S  C++G  C+ D    Y C CP G  G +CE+ V  
Sbjct: 679 YSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDD 736

Query: 180 ----LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               +DP+  +  C NNG+C    GG + + P
Sbjct: 737 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 768



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 30/75 (40%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG+ C+ D  + C S  C HG  C +DG G Y C CP GY G  C+   +L
Sbjct: 517 FTCLCPPGFTGSYCQHDVNE-CDSQPCLHGGTC-QDGCGSYRCTCPQGYTGPNCQ---NL 571

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC+N G C
Sbjct: 572 VHWCDSSPCKNGGKC 586



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 29/75 (38%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +CE +  D C  ++C +G  CV DG   ++C CPPG+ G+YC+ +V+ 
Sbjct: 479 YTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCV-DGINSFTCLCPPGFTGSYCQHDVN- 535

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G+C
Sbjct: 536 --ECDSQPCLHGGTC 548



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 42/87 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C    TG NCE++  D CAS+ C  G  C++   G Y C C PGY G+ C + +  
Sbjct: 137 YLCFCLKGTTGPNCEINL-DDCASSPCDSGT-CLDKIDG-YECACEPGYTGSMCNINID- 192

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C   PC N G+C     G T   P
Sbjct: 193 --ECAGNPCHNGGTCEDGINGFTCRCP 217



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYD 475
           + DEC+ ++ CL+ GRC+D +N + C+C  TG+TG  C+ +V+EC      C +G  C D
Sbjct: 2   NTDECA-SSPCLHNGRCLDKINEFQCEC-PTGFTGHLCQYDVDECAS--TPCKNGAKCLD 57

Query: 476 TYGGFVCACQPATPGSTATGC 538
               + C C   T G T T C
Sbjct: 58  GPNTYTCVC---TEGYTGTHC 75



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G NC+ +  + CAS  C +   C++D  G Y C+C   Y G  CE  V L
Sbjct: 287 YVCTCREGFSGPNCQTNINE-CASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCE--VVL 342

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
            P C   PCRN G C      +++S
Sbjct: 343 AP-CAPSPCRNGGECRQSEDYESFS 366



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 37/73 (50%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G  CE D  + CAS  CR+GA C  D    Y+C CP G+ G +CE   +  P
Sbjct: 443 CDCLPGFRGTFCEEDINE-CASDPCRNGANCT-DCVDSYTCTCPAGFSGIHCE---NNTP 497

Query: 189 LCVAGPCRNNGSC 227
            C    C N G+C
Sbjct: 498 DCTESSCFNGGTC 510



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP G+ G  CE D   C G+  CLNGG C+    + TC C    +TG  C+   
Sbjct: 842  RGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGP-FTGPECQFPA 899

Query: 425  NE-CEEDRALCGHGVCYDT 478
            +  C         G C  T
Sbjct: 900  SSPCLGGNPCYNQGTCEPT 918



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y    C  +  + C S  C HGA C  D    Y CDC PG+ GT C++    
Sbjct: 212 FTCRCPEGYHDPTCLSEVNE-CNSNPCVHGA-C-RDSLNGYKCDCDPGWSGTNCDIN--- 265

Query: 183 DPLCVAGPCRNNGSC 227
           +  C + PC N G+C
Sbjct: 266 NNECESNPCVNGGTC 280



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
           Y C C + +TG  C+V +   C  AA          C+HG  CV+ G   + C C  GY 
Sbjct: 593 YRCECPSGWTGLYCDVPSVS-CEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYT 650

Query: 153 GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           G+YCE    L   C   PC+N  +C+   GG
Sbjct: 651 GSYCE---DLVDECSPSPCQNGATCTDYLGG 678



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 24/66 (36%), Positives = 36/66 (54%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D CAS+ C H  RC+ D   ++ C+CP G+ G  C+ +V     C + PC+N   C    
Sbjct: 4   DECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD---ECASTPCKNGAKCL--D 57

Query: 240 GGDTYS 257
           G +TY+
Sbjct: 58  GPNTYT 63



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
           Y C C   YTG NC+ +    C S+ C++G +C +     Y C+CP G+ G YC++  VS
Sbjct: 555 YRCTCPQGYTGPNCQ-NLVHWCDSSPCKNGGKCWQT-HTQYRCECPSGWTGLYCDVPSVS 612

Query: 180 LDPLC------VAGPCRNNGSC 227
            +         VA  C++ G C
Sbjct: 613 CEVAAQRQGVDVARLCQHGGLC 634



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAAC--RHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   + G  CE D  + C S  C  R    CV+    D+ C+C  G+ G  CE   
Sbjct: 763 YSCTCPPGFVGERCEGDVNE-CLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCE--- 817

Query: 177 SLDPLCVAGPCRNNGSCSV 233
           S+   C   PC+N G+C+V
Sbjct: 818 SVINGCKGKPCKNGGTCAV 836



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGD------PCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTY 161
           Y+C C     G +CE++  D      P + S  C +   CV D  G YSC CPPG+ G  
Sbjct: 717 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGER 775

Query: 162 CELEVSLDPLCVAGPCRNNGS 224
           CE +V+    C++ PC   G+
Sbjct: 776 CEGDVN---ECLSNPCDARGT 793



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
            + C C A +TG  CE    + C    C++G  C       RG + C CP G+ G  CE +
Sbjct: 803  FHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG-FICKCPAGFEGATCEND 860

Query: 174  VSLDPLCVAGPCRNNGSCSVPPGGDT 251
                  C +  C N G+C   P   T
Sbjct: 861  AR---TCGSLRCLNGGTCISGPRSPT 883



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGD-YSCDCPPGYHGTYCEL 170
            C C   +TG  C+  A  PC     C +   C        Y C CP  ++G  C +
Sbjct: 884  CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 939


>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 43/94 (45%), Positives = 54/94 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP G++G  C+ DVDEC+ +  C NG +CVD  + Y C C A G+ G  C+ NV++C 
Sbjct: 493 CTCPSGFSGSTCQLDVDECA-STPCRNGAKCVDQPDGYECRC-AEGFEGTLCDRNVDDCS 550

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
            D   C HG C D    F CAC    PG T T C
Sbjct: 551 PDP--CHHGRCVDGIASFSCAC---APGYTGTRC 579



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 47/102 (46%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
           P     +CTCPPG+TG  C+ DVDECS GA  C + GRCV+   ++ C C   GYTG RC
Sbjct: 370 PVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGPRC 428

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
           ET+VNEC           C D  G F C C     G T T C
Sbjct: 429 ETDVNECLSGPCR-NQATCLDRIGQFTCICM---AGFTGTYC 466



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NCE +VD+C G   CLNGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 222 CACLPGFEGQNCEVNVDDCPG-HRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQ 279

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
                C + G C++T GG  C C     G + +
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/88 (44%), Positives = 51/88 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  CE+ VDEC  +  C +GG+C+D V+ Y C C  +G TG  CE N+++C 
Sbjct: 568 CACAPGYTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRC-PSGTTGVNCEVNIDDCA 625

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C  GVC D    + C CQP   G
Sbjct: 626 SNP--CTFGVCRDGINRYDCVCQPGFTG 651



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 41/91 (45%), Positives = 52/91 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GYTG  CETDV+EC  +  C N   C+D +  +TC C A G+TG  CE +++EC
Sbjct: 416 LCQCGRGYTGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMA-GFTGTYCEVDIDEC 473

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           +    + G GVC D   GF C C     GST
Sbjct: 474 QSSPCVNG-GVCKDRVNGFSCTCPSGFSGST 503



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 41/88 (46%), Positives = 53/88 (60%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPPGY G +CE D+ +CS  ++C NGG CVD VN+++C C   GYTGA C+   + C 
Sbjct: 910  CTCPPGYGGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCL 967

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                L G GVC   + GF C C  +  G
Sbjct: 968  SRPCLHG-GVCSAAHPGFRCTCLESFTG 994



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 36/89 (40%), Positives = 52/89 (58%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C+CP G+ G  C+ DVDEC+G A C   G C +   +++C C   GYTG  C+ ++N+C
Sbjct: 795  VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG-GYTGPSCDQDINDC 853

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +  L G G C D  G F C+C P   G
Sbjct: 854  DPNPCLNG-GSCQDGVGSFSCSCLPGFAG 881



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 42/95 (44%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C C PGY G NCE DVDEC+ +  C +GG C+D V  Y C C   G  G  CE N ++C
Sbjct: 1107 MCECLPGYNGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSC-PPGTLGVLCEINEDDC 1164

Query: 434  EEDRAL-----CGH-GVCYDTYGGFVCACQPATPG 520
                 L     C H G C D  GGF C C P   G
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1199



 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE D+DEC  ++ C+NGG C D VN ++C C  +G++G+ C+ +V+EC 
Sbjct: 455 CICMAGFTGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLDVDECA 512

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGS 523
                C +G  C D   G+ C C     G+
Sbjct: 513 S--TPCRNGAKCVDQPDGYECRCAEGFEGT 540



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC+CPPGY GR+C +DVDEC     C +GG C++   ++ C C A GYTG  CE     C
Sbjct: 143 LCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA-GYTGPLCENPAVPC 201

Query: 434 EEDRALCGHGVCYDTYG-GFVCACQPATPG 520
                  G G C  +    + CAC P   G
Sbjct: 202 APSPCRNG-GTCRQSGDLTYDCACLPGFEG 230



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 37/89 (41%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G TG +CE +VD C  A  C +GG C   +  Y C+C   GY G  CE +V+EC 
Sbjct: 1070 CVCPEGRTGSHCEQEVDPCL-AQPCQHGGTCRGYMGGYMCEC-LPGYNGDNCEDDVDECA 1127

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                 C H G C D    ++C+C P T G
Sbjct: 1128 SQP--CQHGGSCIDLVARYLCSCPPGTLG 1154



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C  +++EC+ ++ C  GG CVD  N + C C   G     C    + C 
Sbjct: 643 CVCQPGFTGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPP-GSLPPLCLPPSHPCA 700

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+CYD  GGF C C+P   G
Sbjct: 701 HEP--CSHGICYDAPGGFRCVCEPGWSG 726



 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 36/88 (40%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CP G TG NCE ++D+C+        G C D +N Y C C   G+TG  C   +NEC
Sbjct: 605 LCRCPSGTTGVNCEVNIDDCASNPCTF--GVCRDGINRYDCVC-QPGFTGPLCNVEINEC 661

Query: 434 EEDRALCGH-GVCYDTYGGFVCACQPAT 514
               + CG  G C D   GF C C P +
Sbjct: 662 AS--SPCGEGGSCVDGENGFRCLCPPGS 687



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/87 (39%), Positives = 43/87 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C +   DPC S+ C HGARC     G + C CPPGY G  C  +V  
Sbjct: 104 FSCRCPRGFRGPDCSLP--DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV-- 159

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D   V  PCR+ G+C   PG      P
Sbjct: 160 DECRVGEPCRHGGTCLNTPGSFRCQCP 186



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C PG+ G  C  DVDEC  +  C   G C D V ++TC C   GY G  CE ++ +C 
Sbjct: 873  CSCLPGFAGPRCARDVDECL-SNPC-GPGTCTDHVASFTCTC-PPGYGGFHCEQDLPDCS 929

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G G C D    F C C+P   G+
Sbjct: 930  PSSCFNG-GTCVDGVNSFSCLCRPGYTGA 957



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/81 (40%), Positives = 44/81 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +TG  CEVD  D C S+ C +G  C +   G +SC CP G+ G+ C+L+V  
Sbjct: 453 FTCICMAGFTGTYCEVDI-DECQSSPCVNGGVCKDRVNG-FSCTCPSGFSGSTCQLDVD- 509

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C + PCRN   C   P G
Sbjct: 510 --ECASTPCRNGAKCVDQPDG 528



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
            Y C C   Y G+NCE D  D CAS  C+HG  C+ D    Y C CPPG  G  CE+   +
Sbjct: 1106 YMCECLPGYNGDNCEDDV-DECASQPCQHGGSCI-DLVARYLCSCPPGTLGVLCEINEDD 1163

Query: 174  VSLDPLCVAGP-CRNNGSCSVPPGGDTYSAP 263
                P   +GP C +NG+C    GG   + P
Sbjct: 1164 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 37/90 (41%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCETNVNEC 433
            CTCPPG  GR CE  +  C+    C +GGRC  A      C C   G+ G RC+ +V+EC
Sbjct: 758  CTCPPGVQGRQCEL-LSPCT-PNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRCQQDVDEC 814

Query: 434  EEDRALCG-HGVCYDTYGGFVCACQPATPG 520
                A CG HG+C +  G F C C     G
Sbjct: 815  -AGPAPCGPHGICTNLAGSFSCTCHGGYTG 843



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   + G  C+ +  D C+   C HG RCV DG   +SC C PGY GT CE +V  
Sbjct: 529 YECRCAEGFEGTLCDRNVDD-CSPDPCHHG-RCV-DGIASFSCACAPGYTGTRCESQVD- 584

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G C
Sbjct: 585 --ECRSQPCRHGGKC 597



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/85 (37%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  CE D  + C S  CR+ A C+ D  G ++C C  G+ GTYCE+++    
Sbjct: 417 CQCGRGYTGPRCETDVNE-CLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCEVDID--- 471

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C + PC N G C     G + + P
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCP 496



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C   ++G  C    A D C S  CR G  C  DG G + C CPPG  G  CEL   
Sbjct: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCEL--- 771

Query: 180 LDPLCVAGPCRNNGSCSVPPG 242
           L P C   PC + G C   PG
Sbjct: 772 LSP-CTPNPCEHGGRCESAPG 791



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y G +CE D  D C+ ++C +G  CV DG   +SC C PGY G +C+ E   
Sbjct: 908  FTCTCPPGYGGFHCEQDLPD-CSPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHEA-- 963

Query: 183  DPLCVAGPCRNNGSCSVP-PG 242
            DP C++ PC + G CS   PG
Sbjct: 964  DP-CLSRPCLHGGVCSAAHPG 983



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/73 (41%), Positives = 41/73 (56%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C    TG++CE +  DPC +  C+HG  C     G Y C+C PGY+G  CE +V    
Sbjct: 1070 CVCPEGRTGSHCEQEV-DPCLAQPCQHGGTC-RGYMGGYMCECLPGYNGDNCEDDVD--- 1124

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1125 ECASQPCQHGGSC 1137



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNE 430
            CTCPPGYTG  CE D++EC SGA    +   C+ D    + C C A G++G RC+T ++ 
Sbjct: 1191 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSP 1249

Query: 431  CEEDRALCGH-GVCYDT---YGGFVCACQPATP 517
            CE     C H G C  +    GG    C  A P
Sbjct: 1250 CESQP--CQHGGQCRPSPGPGGGLTFTCHCAQP 1280



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/85 (41%), Positives = 44/85 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A YTG  CE  A  PCA + CR+G  C + G   Y C C PG+ G  CE+ V  
Sbjct: 181 FRCQCPAGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD- 238

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C N G+C    G +TY+
Sbjct: 239 D--CPGHRCLNGGTC--VDGVNTYN 259



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CPPG++GR C+     C  AAA         C  GG+CVD  +++ C C   G TG+ 
Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC-PEGRTGSH 1080

Query: 410  CETNVNECEEDRALCGH-GVCYDTYGGFVCACQPATPG 520
            CE  V+ C      C H G C    GG++C C P   G
Sbjct: 1081 CEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNG 1116



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G NCEV+  D C    C +G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 220 YDCACLPGFEGQNCEVNVDD-CPGHRCLNGGTCV-DGVNTYNCQCPPEWTGQFCTEDVDE 277

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L     C N G+C    GG
Sbjct: 278 CQL-QPNACHNGGTCFNTLGG 297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/75 (42%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C +  TG NCEV+  D CAS  C  G  C  DG   Y C C PG+ G  C +E++ 
Sbjct: 604 YLCRCPSGTTGVNCEVNIDD-CASNPCTFGV-C-RDGINRYDCVCQPGFTGPLCNVEIN- 659

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC   GSC
Sbjct: 660 --ECASSPCGEGGSC 672



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 28/73 (38%), Positives = 33/73 (45%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C  D  +      CRHG  C+    G + C CP GY G  CE      P
Sbjct: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAV--P 200

Query: 189 LCVAGPCRNNGSC 227
            C   PCRN G+C
Sbjct: 201 -CAPSPCRNGGTC 212



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C   +TG  C+ D  D C+  A  C H  RCV   +G + C C  GY G  CE +V+ 
Sbjct: 377 CTCPPGFTGGACDQDV-DECSIGANPCEHLGRCVNT-QGSFLCQCGRGYTGPRCETDVN- 433

Query: 183 DPLCVAGPCRNNGSC 227
              C++GPCRN  +C
Sbjct: 434 --ECLSGPCRNQATC 446



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACR--HGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            + C C   YTG  CE D  + C S AC   H   C++D  G + C C  G+ G  C  + 
Sbjct: 1189 FRCTCPPGYTGLRCEADINE-CRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC--QT 1245

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
             L P C + PC++ G C   PG
Sbjct: 1246 VLSP-CESQPCQHGGQCRPSPG 1266



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            + C C   YTG +C+ D  D C    C +G  C +DG G +SC C PG+ G  C  +V  
Sbjct: 833  FSCTCHGGYTGPSCDQDIND-CDPNPCLNGGSC-QDGVGSFSCSCLPGFAGPRCARDVDE 890

Query: 180  -LDPLCVAGPCRN---NGSCSVPPG 242
             L   C  G C +   + +C+ PPG
Sbjct: 891  CLSNPCGPGTCTDHVASFTCTCPPG 915



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/79 (36%), Positives = 37/79 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG +C  +  D CA+A C HGA C  D    + C CP G  G  C L    
Sbjct: 298 HSCVCVNGWTGESCSQNIDD-CATAVCFHGATC-HDRVASFYCACPMGKTGLLCHL---- 351

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           D  CV+ PC  +  C   P
Sbjct: 352 DDACVSNPCHEDAICDTNP 370



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           + C C   YTG  CE    D C S  CRHG +C+ D    Y C CP G  G  CE+ +  
Sbjct: 566 FSCACAPGYTGTRCESQV-DECRSQPCRHGGKCL-DLVDKYLCRCPSGTTGVNCEVNIDD 623

Query: 180 -LDPLCVAGPCR---NNGSCSVPPG 242
                C  G CR   N   C   PG
Sbjct: 624 CASNPCTFGVCRDGINRYDCVCQPG 648



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC---VEDGRGDYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+++  DPC S  C     C   V  G   +SC CP G+ G  C L   
Sbjct: 65  CLCPPGWVGERCQLE--DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-- 120

Query: 180 LDPLCVAGPCRNNGSCSVPPGG 245
            DP C++ PC +   CSV P G
Sbjct: 121 -DP-CLSSPCAHGARCSVGPDG 140



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN----V 424
           C C  G+TG +C  ++D+C+  A C +G  C D V ++ C C   G TG  C  +     
Sbjct: 300 CVCVNGWTGESCSQNIDDCA-TAVCFHGATCHDRVASFYCAC-PMGKTGLLCHLDDACVS 357

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           N C ED A+C         G  +C C P   G
Sbjct: 358 NPCHED-AICDTN---PVNGRAICTCPPGFTG 385



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 33/81 (40%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C V+  + CAS+ C  G  CV DG   + C CPPG     C L  S 
Sbjct: 641 YDCVCQPGFTGPLCNVEINE-CASSPCGEGGSCV-DGENGFRCLCPPGSLPPLC-LPPS- 696

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
            P C   PC ++G C   PGG
Sbjct: 697 HP-CAHEPC-SHGICYDAPGG 715



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   YTG +C+ +A DPC S  C HG  C     G + C C   + G  C+   +L
Sbjct: 946  FSCLCRPGYTGAHCQHEA-DPCLSRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQ---TL 1000

Query: 183  DPLCVAGPCRNNGSC 227
               C   PC+N G C
Sbjct: 1001 VDWCSRQPCQNGGRC 1015



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 10/89 (11%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            C C   ++G  C++ +  PC  AA          C+ G +CV++    Y C CP G  G+
Sbjct: 1022 CLCPPGWSGRLCDIRSL-PCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-CVCPEGRTGS 1079

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            +CE EV  DP C+A PC++ G+C    GG
Sbjct: 1080 HCEQEV--DP-CLAQPCQHGGTCRGYMGG 1105



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 27/75 (36%), Positives = 35/75 (46%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  D  D C S  C  G  C  D    ++C CPPGY G +CE ++  
Sbjct: 871  FSCSCLPGFAGPRCARDV-DECLSNPCGPGT-CT-DHVASFTCTCPPGYGGFHCEQDL-- 925

Query: 183  DPLCVAGPCRNNGSC 227
             P C    C N G+C
Sbjct: 926  -PDCSPSSCFNGGTC 939



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + CHC   + G  CE  A   C    C  G  C +  RG   C CPPG  G  C      
Sbjct: 1273 FTCHCAQPFWGPRCERVARS-CRELQCPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGS 1330

Query: 183  DP-----LCVAGPCRNNGSCSVPP 239
             P      C A PC + GSC   P
Sbjct: 1331 PPGASNASCAAAPCLHGGSCRPAP 1354



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC   +TG  C+T VD CS    C NGGRCV       C C   G++G  C+     C 
Sbjct: 986  CTCLESFTGPQCQTLVDWCS-RQPCQNGGRCVQ--TGAYCLC-PPGWSGRLCDIRSLPCR 1041

Query: 437  EDRA--------LC-GHGVCYDTYGGFVCACQPATPGS 523
            E  A        LC   G C D      C C     GS
Sbjct: 1042 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGS 1079



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS-CDCPPGYHGTYCELEVS 179
           + C C     G  CE+ +  PC    C HG RC E   G    C CP G+ G  C+ +V 
Sbjct: 756 FHCTCPPGVQGRQCELLS--PCTPNPCEHGGRC-ESAPGQLPVCSCPQGWQGPRCQQDV- 811

Query: 180 LDPLCVAGPCRNNGSCS 230
            D      PC  +G C+
Sbjct: 812 -DECAGPAPCGPHGICT 827



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           A  PC   + C +G RC +    + +C CPPG+ G  C+LE   DP C +GPC   G C
Sbjct: 39  AAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE---DP-CHSGPCAGRGVC 93



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-----GDYSCDCPPGYHGTYCE 167
            Y C C     G  CE++  D         G RC+ +G      G + C CPPGY G  CE
Sbjct: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203

Query: 168  LEVSLDPLCVAGPCR--NNGSCSVPPGG 245
             +++    C +G C   +   C   PGG
Sbjct: 1204 ADIN---ECRSGACHAAHTRDCLQDPGG 1228



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 23/56 (41%), Positives = 29/56 (51%)
 Frame = +3

Query: 63  PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           PCA   C HG  C  D  G + C C PG+ G  C   ++ D  C + PCR  G+CS
Sbjct: 698 PCAHEPCSHGI-CY-DAPGGFRCVCEPGWSGPRCSQSLARD-ACESQPCRAGGTCS 750



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 10/111 (9%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSG-------AAACLNGGRCVDA--VNNY 370
            +Q  R PR     C CPPG +G +C +      G       AA CL+GG C  A     +
Sbjct: 1305 QQTPRGPR-----CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF 1359

Query: 371  TCDCTATGYTGARCETNVNECE-EDRALCGHGVCYDTYGGFVCACQPATPG 520
             C C A G+TG RCE      E  +   C    C    G   C  +  +PG
Sbjct: 1360 RCAC-AQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAV----NNYTCDCTATGYTGARC 412
           R   C CPPG+ G  C+ + D C  +  C   G C  +V      ++C C   G+ G  C
Sbjct: 61  REAACLCPPGWVGERCQLE-DPCH-SGPCAGRGVCQSSVVAGTARFSCRC-PRGFRGPDC 117

Query: 413 ETNVNECEEDRALCGHGV-C-YDTYGGFVCACQPATPG 520
               + C    + C HG  C     G F+C+C P   G
Sbjct: 118 SL-PDPCLS--SPCAHGARCSVGPDGRFLCSCPPGYQG 152



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC +G  C  +  G +SC C  G+ G  C   +
Sbjct: 258 YNCQCPPEWTGQFCTEDV-DECQLQPNACHNGGTCF-NTLGGHSCVCVNGWTGESCSQNI 315

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C +  +C
Sbjct: 316 D-D--CATAVCFHGATC 329



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDV--DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           C C PG++G  C   +  D C  +  C  GG C      + C C   G  G +CE  ++ 
Sbjct: 718 CVCEPGWSGPRCSQSLARDACE-SQPCRAGGTCSSDGMGFHCTC-PPGVQGRQCEL-LSP 774

Query: 431 CEEDRALCGH-GVCYDTYGGF-VCACQPATPG 520
           C  +   C H G C    G   VC+C     G
Sbjct: 775 CTPNP--CEHGGRCESAPGQLPVCSCPQGWQG 804



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD--CPP---GYHGTYCE 167
            + C C   +TG  CE  A  P  S   R      +  RGD  CD  C     G+ G  C 
Sbjct: 1359 FRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCS 1418

Query: 168  LEVSLDP--LCVAGPC---RNNGSC 227
            L V  DP   C A  C    NN  C
Sbjct: 1419 LSVG-DPWRQCEALQCWRLFNNSRC 1442



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 4/68 (5%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTY--- 481
           C   + C NGGRC    +         G+ G RC+   + C       G GVC  +    
Sbjct: 43  CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSG-PCAGRGVCQSSVVAG 100

Query: 482 -GGFVCAC 502
              F C C
Sbjct: 101 TARFSCRC 108



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +3

Query: 573 ACVEEGGGFRCVCARGYLPPL 635
           +CV+   GFRC+C  G LPPL
Sbjct: 671 SCVDGENGFRCLCPPGSLPPL 691


>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 43/94 (45%), Positives = 54/94 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP G++G  C+ DVDEC+ +  C NG +CVD  + Y C C A G+ G  C+ NV++C 
Sbjct: 493 CTCPSGFSGSTCQLDVDECA-STPCRNGAKCVDQPDGYECRC-AEGFEGTLCDRNVDDCS 550

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
            D   C HG C D    F CAC    PG T T C
Sbjct: 551 PDP--CHHGRCVDGIASFSCAC---APGYTGTRC 579



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 47/102 (46%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
           P     +CTCPPG+TG  C+ DVDECS GA  C + GRCV+   ++ C C   GYTG RC
Sbjct: 370 PVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGPRC 428

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
           ET+VNEC           C D  G F C C     G T T C
Sbjct: 429 ETDVNECLSGPCR-NQATCLDRIGQFTCICM---AGFTGTYC 466



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NCE +VD+C G   CLNGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 222 CACLPGFEGQNCEVNVDDCPG-HRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQ 279

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
                C + G C++T GG  C C     G + +
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/88 (44%), Positives = 51/88 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  CE+ VDEC  +  C +GG+C+D V+ Y C C  +G TG  CE N+++C 
Sbjct: 568 CACAPGYTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRC-PSGTTGVNCEVNIDDCA 625

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C  GVC D    + C CQP   G
Sbjct: 626 SNP--CTFGVCRDGINRYDCVCQPGFTG 651



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 41/91 (45%), Positives = 52/91 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GYTG  CETDV+EC  +  C N   C+D +  +TC C A G+TG  CE +++EC
Sbjct: 416 LCQCGRGYTGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMA-GFTGTYCEVDIDEC 473

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           +    + G GVC D   GF C C     GST
Sbjct: 474 QSSPCVNG-GVCKDRVNGFSCTCPSGFSGST 503



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 41/88 (46%), Positives = 53/88 (60%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPPGY G +CE D+ +CS  ++C NGG CVD VN+++C C   GYTGA C+   + C 
Sbjct: 910  CTCPPGYGGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCL 967

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                L G GVC   + GF C C  +  G
Sbjct: 968  SRPCLHG-GVCSAAHPGFRCTCLESFTG 994



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 36/89 (40%), Positives = 52/89 (58%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C+CP G+ G  C+ DVDEC+G A C   G C +   +++C C   GYTG  C+ ++N+C
Sbjct: 795  VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG-GYTGPSCDQDINDC 853

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +  L G G C D  G F C+C P   G
Sbjct: 854  DPNPCLNG-GSCQDGVGSFSCSCLPGFAG 881



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 42/95 (44%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C C PGY G NCE DVDEC+ +  C +GG C+D V  Y C C   G  G  CE N ++C
Sbjct: 1107 MCECLPGYNGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSC-PPGTLGVLCEINEDDC 1164

Query: 434  EEDRAL-----CGH-GVCYDTYGGFVCACQPATPG 520
                 L     C H G C D  GGF C C P   G
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1199



 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE D+DEC  ++ C+NGG C D VN ++C C  +G++G+ C+ +V+EC 
Sbjct: 455 CICMAGFTGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLDVDECA 512

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGS 523
                C +G  C D   G+ C C     G+
Sbjct: 513 S--TPCRNGAKCVDQPDGYECRCAEGFEGT 540



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC+CPPGY GR+C +DVDEC     C +GG C++   ++ C C A GYTG  CE     C
Sbjct: 143 LCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA-GYTGPLCENPAVPC 201

Query: 434 EEDRALCGHGVCYDTYG-GFVCACQPATPG 520
                  G G C  +    + CAC P   G
Sbjct: 202 APSPCRNG-GTCRQSGDLTYDCACLPGFEG 230



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 37/89 (41%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G TG +CE +VD C  A  C +GG C   +  Y C+C   GY G  CE +V+EC 
Sbjct: 1070 CVCPEGRTGSHCEQEVDPCL-AQPCQHGGTCRGYMGGYMCEC-LPGYNGDNCEDDVDECA 1127

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                 C H G C D    ++C+C P T G
Sbjct: 1128 SQP--CQHGGSCIDLVARYLCSCPPGTLG 1154



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C  +++EC+ ++ C  GG CVD  N + C C   G     C    + C 
Sbjct: 643 CVCQPGFTGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPP-GSLPPLCLPPSHPCA 700

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+CYD  GGF C C+P   G
Sbjct: 701 HEP--CSHGICYDAPGGFRCVCEPGWSG 726



 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 36/88 (40%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CP G TG NCE ++D+C+        G C D +N Y C C   G+TG  C   +NEC
Sbjct: 605 LCRCPSGTTGVNCEVNIDDCASNPCTF--GVCRDGINRYDCVC-QPGFTGPLCNVEINEC 661

Query: 434 EEDRALCGH-GVCYDTYGGFVCACQPAT 514
               + CG  G C D   GF C C P +
Sbjct: 662 AS--SPCGEGGSCVDGENGFRCLCPPGS 687



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/87 (39%), Positives = 43/87 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C +   DPC S+ C HGARC     G + C CPPGY G  C  +V  
Sbjct: 104 FSCRCPRGFRGPDCSLP--DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV-- 159

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D   V  PCR+ G+C   PG      P
Sbjct: 160 DECRVGEPCRHGGTCLNTPGSFRCQCP 186



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C PG+ G  C  DVDEC  +  C   G C D V ++TC C   GY G  CE ++ +C 
Sbjct: 873  CSCLPGFAGPRCARDVDECL-SNPC-GPGTCTDHVASFTCTC-PPGYGGFHCEQDLPDCS 929

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G G C D    F C C+P   G+
Sbjct: 930  PSSCFNG-GTCVDGVNSFSCLCRPGYTGA 957



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/81 (40%), Positives = 44/81 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +TG  CEVD  D C S+ C +G  C +   G +SC CP G+ G+ C+L+V  
Sbjct: 453 FTCICMAGFTGTYCEVDI-DECQSSPCVNGGVCKDRVNG-FSCTCPSGFSGSTCQLDVD- 509

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C + PCRN   C   P G
Sbjct: 510 --ECASTPCRNGAKCVDQPDG 528



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
            Y C C   Y G+NCE D  D CAS  C+HG  C+ D    Y C CPPG  G  CE+   +
Sbjct: 1106 YMCECLPGYNGDNCEDDV-DECASQPCQHGGSCI-DLVARYLCSCPPGTLGVLCEINEDD 1163

Query: 174  VSLDPLCVAGP-CRNNGSCSVPPGGDTYSAP 263
                P   +GP C +NG+C    GG   + P
Sbjct: 1164 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 37/90 (41%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCETNVNEC 433
            CTCPPG  GR CE  +  C+    C +GGRC  A      C C   G+ G RC+ +V+EC
Sbjct: 758  CTCPPGVQGRQCEL-LSPCT-PNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRCQQDVDEC 814

Query: 434  EEDRALCG-HGVCYDTYGGFVCACQPATPG 520
                A CG HG+C +  G F C C     G
Sbjct: 815  -AGPAPCGPHGICTNLAGSFSCTCHGGYTG 843



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   + G  C+ +  D C+   C HG RCV DG   +SC C PGY GT CE +V  
Sbjct: 529 YECRCAEGFEGTLCDRNVDD-CSPDPCHHG-RCV-DGIASFSCACAPGYTGTRCESQVD- 584

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G C
Sbjct: 585 --ECRSQPCRHGGKC 597



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/85 (37%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  CE D  + C S  CR+ A C+ D  G ++C C  G+ GTYCE+++    
Sbjct: 417 CQCGRGYTGPRCETDVNE-CLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCEVDID--- 471

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C + PC N G C     G + + P
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCP 496



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C   ++G  C    A D C S  CR G  C  DG G + C CPPG  G  CEL   
Sbjct: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCEL--- 771

Query: 180 LDPLCVAGPCRNNGSCSVPPG 242
           L P C   PC + G C   PG
Sbjct: 772 LSP-CTPNPCEHGGRCESAPG 791



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y G +CE D  D C+ ++C +G  CV DG   +SC C PGY G +C+ E   
Sbjct: 908  FTCTCPPGYGGFHCEQDLPD-CSPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHEA-- 963

Query: 183  DPLCVAGPCRNNGSCSVP-PG 242
            DP C++ PC + G CS   PG
Sbjct: 964  DP-CLSRPCLHGGVCSAAHPG 983



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/73 (41%), Positives = 41/73 (56%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C    TG++CE +  DPC +  C+HG  C     G Y C+C PGY+G  CE +V    
Sbjct: 1070 CVCPEGRTGSHCEQEV-DPCLAQPCQHGGTC-RGYMGGYMCECLPGYNGDNCEDDVD--- 1124

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1125 ECASQPCQHGGSC 1137



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNE 430
            CTCPPGYTG  CE D++EC SGA    +   C+ D    + C C A G++G RC+T ++ 
Sbjct: 1191 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSP 1249

Query: 431  CEEDRALCGH-GVCYDT---YGGFVCACQPATP 517
            CE     C H G C  +    GG    C  A P
Sbjct: 1250 CESQP--CQHGGQCRPSPGPGGGLTFTCHCAQP 1280



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/85 (41%), Positives = 44/85 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A YTG  CE  A  PCA + CR+G  C + G   Y C C PG+ G  CE+ V  
Sbjct: 181 FRCQCPAGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD- 238

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C N G+C    G +TY+
Sbjct: 239 D--CPGHRCLNGGTC--VDGVNTYN 259



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CPPG++GR C+     C  AAA         C  GG+CVD  +++ C C   G TG+ 
Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC-PEGRTGSH 1080

Query: 410  CETNVNECEEDRALCGH-GVCYDTYGGFVCACQPATPG 520
            CE  V+ C      C H G C    GG++C C P   G
Sbjct: 1081 CEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNG 1116



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G NCEV+  D C    C +G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 220 YDCACLPGFEGQNCEVNVDD-CPGHRCLNGGTCV-DGVNTYNCQCPPEWTGQFCTEDVDE 277

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L     C N G+C    GG
Sbjct: 278 CQL-QPNACHNGGTCFNTLGG 297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/75 (42%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C +  TG NCEV+  D CAS  C  G  C  DG   Y C C PG+ G  C +E++ 
Sbjct: 604 YLCRCPSGTTGVNCEVNIDD-CASNPCTFGV-C-RDGINRYDCVCQPGFTGPLCNVEIN- 659

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC   GSC
Sbjct: 660 --ECASSPCGEGGSC 672



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 28/73 (38%), Positives = 33/73 (45%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C  D  +      CRHG  C+    G + C CP GY G  CE      P
Sbjct: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAV--P 200

Query: 189 LCVAGPCRNNGSC 227
            C   PCRN G+C
Sbjct: 201 -CAPSPCRNGGTC 212



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C   +TG  C+ D  D C+  A  C H  RCV   +G + C C  GY G  CE +V+ 
Sbjct: 377 CTCPPGFTGGACDQDV-DECSIGANPCEHLGRCVNT-QGSFLCQCGRGYTGPRCETDVN- 433

Query: 183 DPLCVAGPCRNNGSC 227
              C++GPCRN  +C
Sbjct: 434 --ECLSGPCRNQATC 446



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACR--HGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            + C C   YTG  CE D  + C S AC   H   C++D  G + C C  G+ G  C  + 
Sbjct: 1189 FRCTCPPGYTGLRCEADINE-CRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC--QT 1245

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
             L P C + PC++ G C   PG
Sbjct: 1246 VLSP-CESQPCQHGGQCRPSPG 1266



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            + C C   YTG +C+ D  D C    C +G  C +DG G +SC C PG+ G  C  +V  
Sbjct: 833  FSCTCHGGYTGPSCDQDIND-CDPNPCLNGGSC-QDGVGSFSCSCLPGFAGPRCARDVDE 890

Query: 180  -LDPLCVAGPCRN---NGSCSVPPG 242
             L   C  G C +   + +C+ PPG
Sbjct: 891  CLSNPCGPGTCTDHVASFTCTCPPG 915



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/79 (36%), Positives = 37/79 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG +C  +  D CA+A C HGA C  D    + C CP G  G  C L    
Sbjct: 298 HSCVCVNGWTGESCSQNIDD-CATAVCFHGATC-HDRVASFYCACPMGKTGLLCHL---- 351

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           D  CV+ PC  +  C   P
Sbjct: 352 DDACVSNPCHEDAICDTNP 370



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           + C C   YTG  CE    D C S  CRHG +C+ D    Y C CP G  G  CE+ +  
Sbjct: 566 FSCACAPGYTGTRCESQV-DECRSQPCRHGGKCL-DLVDKYLCRCPSGTTGVNCEVNIDD 623

Query: 180 -LDPLCVAGPCR---NNGSCSVPPG 242
                C  G CR   N   C   PG
Sbjct: 624 CASNPCTFGVCRDGINRYDCVCQPG 648



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC---VEDGRGDYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+++  DPC S  C     C   V  G   +SC CP G+ G  C L   
Sbjct: 65  CLCPPGWVGERCQLE--DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-- 120

Query: 180 LDPLCVAGPCRNNGSCSVPPGG 245
            DP C++ PC +   CSV P G
Sbjct: 121 -DP-CLSSPCAHGARCSVGPDG 140



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN----V 424
           C C  G+TG +C  ++D+C+  A C +G  C D V ++ C C   G TG  C  +     
Sbjct: 300 CVCVNGWTGESCSQNIDDCA-TAVCFHGATCHDRVASFYCAC-PMGKTGLLCHLDDACVS 357

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           N C ED A+C         G  +C C P   G
Sbjct: 358 NPCHED-AICDTN---PVNGRAICTCPPGFTG 385



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 33/81 (40%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C V+  + CAS+ C  G  CV DG   + C CPPG     C L  S 
Sbjct: 641 YDCVCQPGFTGPLCNVEINE-CASSPCGEGGSCV-DGENGFRCLCPPGSLPPLC-LPPS- 696

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
            P C   PC ++G C   PGG
Sbjct: 697 HP-CAHEPC-SHGICYDAPGG 715



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   YTG +C+ +A DPC S  C HG  C     G + C C   + G  C+   +L
Sbjct: 946  FSCLCRPGYTGAHCQHEA-DPCLSRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQ---TL 1000

Query: 183  DPLCVAGPCRNNGSC 227
               C   PC+N G C
Sbjct: 1001 VDWCSRQPCQNGGRC 1015



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 10/89 (11%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            C C   ++G  C++ +  PC  AA          C+ G +CV++    Y C CP G  G+
Sbjct: 1022 CLCPPGWSGRLCDIRSL-PCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-CVCPEGRTGS 1079

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            +CE EV  DP C+A PC++ G+C    GG
Sbjct: 1080 HCEQEV--DP-CLAQPCQHGGTCRGYMGG 1105



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 27/75 (36%), Positives = 35/75 (46%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  D  D C S  C  G  C  D    ++C CPPGY G +CE ++  
Sbjct: 871  FSCSCLPGFAGPRCARDV-DECLSNPCGPGT-CT-DHVASFTCTCPPGYGGFHCEQDL-- 925

Query: 183  DPLCVAGPCRNNGSC 227
             P C    C N G+C
Sbjct: 926  -PDCSPSSCFNGGTC 939



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + CHC   + G  CE  A   C    C  G  C +  RG   C CPPG  G  C      
Sbjct: 1273 FTCHCAQPFWGPRCERVARS-CRELQCPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGS 1330

Query: 183  DP-----LCVAGPCRNNGSCSVPP 239
             P      C A PC + GSC   P
Sbjct: 1331 PPGASNASCAAAPCLHGGSCRPAP 1354



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC   +TG  C+T VD CS    C NGGRCV       C C   G++G  C+     C 
Sbjct: 986  CTCLESFTGPQCQTLVDWCS-RQPCQNGGRCVQ--TGAYCLC-PPGWSGRLCDIRSLPCR 1041

Query: 437  EDRA--------LC-GHGVCYDTYGGFVCACQPATPGS 523
            E  A        LC   G C D      C C     GS
Sbjct: 1042 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGS 1079



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS-CDCPPGYHGTYCELEVS 179
           + C C     G  CE+ +  PC    C HG RC E   G    C CP G+ G  C+ +V 
Sbjct: 756 FHCTCPPGVQGRQCELLS--PCTPNPCEHGGRC-ESAPGQLPVCSCPQGWQGPRCQQDV- 811

Query: 180 LDPLCVAGPCRNNGSCS 230
            D      PC  +G C+
Sbjct: 812 -DECAGPAPCGPHGICT 827



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           A  PC   + C +G RC +    + +C CPPG+ G  C+LE   DP C +GPC   G C
Sbjct: 39  AAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE---DP-CHSGPCAGRGVC 93



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-----GDYSCDCPPGYHGTYCE 167
            Y C C     G  CE++  D         G RC+ +G      G + C CPPGY G  CE
Sbjct: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203

Query: 168  LEVSLDPLCVAGPCR--NNGSCSVPPGG 245
             +++    C +G C   +   C   PGG
Sbjct: 1204 ADIN---ECRSGACHAAHTRDCLQDPGG 1228



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 23/56 (41%), Positives = 29/56 (51%)
 Frame = +3

Query: 63  PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           PCA   C HG  C  D  G + C C PG+ G  C   ++ D  C + PCR  G+CS
Sbjct: 698 PCAHEPCSHGI-CY-DAPGGFRCVCEPGWSGPRCSQSLARD-ACESQPCRAGGTCS 750



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 10/111 (9%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSG-------AAACLNGGRCVDA--VNNY 370
            +Q  R PR     C CPPG +G +C +      G       AA CL+GG C  A     +
Sbjct: 1305 QQTPRGPR-----CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF 1359

Query: 371  TCDCTATGYTGARCETNVNECE-EDRALCGHGVCYDTYGGFVCACQPATPG 520
             C C A G+TG RCE      E  +   C    C    G   C  +  +PG
Sbjct: 1360 RCAC-AQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1409



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAV----NNYTCDCTATGYTGARC 412
           R   C CPPG+ G  C+ + D C  +  C   G C  +V      ++C C   G+ G  C
Sbjct: 61  REAACLCPPGWVGERCQLE-DPCH-SGPCAGRGVCQSSVVAGTARFSCRC-PRGFRGPDC 117

Query: 413 ETNVNECEEDRALCGHGV-C-YDTYGGFVCACQPATPG 520
               + C    + C HG  C     G F+C+C P   G
Sbjct: 118 SL-PDPCLS--SPCAHGARCSVGPDGRFLCSCPPGYQG 152



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC +G  C  +  G +SC C  G+ G  C   +
Sbjct: 258 YNCQCPPEWTGQFCTEDV-DECQLQPNACHNGGTCF-NTLGGHSCVCVNGWTGESCSQNI 315

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C +  +C
Sbjct: 316 D-D--CATAVCFHGATC 329



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDV--DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           C C PG++G  C   +  D C  +  C  GG C      + C C   G  G +CE  ++ 
Sbjct: 718 CVCEPGWSGPRCSQSLARDACE-SQPCRAGGTCSSDGMGFHCTC-PPGVQGRQCEL-LSP 774

Query: 431 CEEDRALCGH-GVCYDTYGGF-VCACQPATPG 520
           C  +   C H G C    G   VC+C     G
Sbjct: 775 CTPNP--CEHGGRCESAPGQLPVCSCPQGWQG 804



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD--CPP---GYHGTYCE 167
            + C C   +TG  CE  A  P  S   R      +  RGD  CD  C     G+ G  C 
Sbjct: 1359 FRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCS 1418

Query: 168  LEVSLDP--LCVAGPC---RNNGSC 227
            L V  DP   C A  C    NN  C
Sbjct: 1419 LSVG-DPWRQCEALQCWRLFNNSRC 1442



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 4/68 (5%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTY--- 481
           C   + C NGGRC    +         G+ G RC+   + C       G GVC  +    
Sbjct: 43  CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSG-PCAGRGVCQSSVVAG 100

Query: 482 -GGFVCAC 502
              F C C
Sbjct: 101 TARFSCRC 108



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +3

Query: 573 ACVEEGGGFRCVCARGYLPPL 635
           +CV+   GFRC+C  G LPPL
Sbjct: 671 SCVDGENGFRCLCPPGSLPPL 691


>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
          Length = 2281

 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 43/94 (45%), Positives = 54/94 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP G++G  C+ DVDEC+ +  C NG +CVD  + Y C C A G+ G  C+ NV++C 
Sbjct: 453 CTCPSGFSGSTCQLDVDECA-STPCRNGAKCVDQPDGYECRC-AEGFEGTLCDRNVDDCS 510

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
            D   C HG C D    F CAC    PG T T C
Sbjct: 511 PDP--CHHGRCVDGIASFSCAC---APGYTGTRC 539



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 47/102 (46%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
           P     +CTCPPG+TG  C+ DVDECS GA  C + GRCV+   ++ C C   GYTG RC
Sbjct: 330 PVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGPRC 388

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
           ET+VNEC           C D  G F C C     G T T C
Sbjct: 389 ETDVNECLSGPCR-NQATCLDRIGQFTCICM---AGFTGTYC 426



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NCE +VD+C G   CLNGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 182 CACLPGFEGQNCEVNVDDCPG-HRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQ 239

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
                C + G C++T GG  C C     G + +
Sbjct: 240 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 272



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/88 (44%), Positives = 51/88 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  CE+ VDEC  +  C +GG+C+D V+ Y C C  +G TG  CE N+++C 
Sbjct: 528 CACAPGYTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRC-PSGTTGVNCEVNIDDCA 585

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C  GVC D    + C CQP   G
Sbjct: 586 SNP--CTFGVCRDGINRYDCVCQPGFTG 611



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 41/91 (45%), Positives = 52/91 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GYTG  CETDV+EC  +  C N   C+D +  +TC C A G+TG  CE +++EC
Sbjct: 376 LCQCGRGYTGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMA-GFTGTYCEVDIDEC 433

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           +    + G GVC D   GF C C     GST
Sbjct: 434 QSSPCVNG-GVCKDRVNGFSCTCPSGFSGST 463



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 41/88 (46%), Positives = 53/88 (60%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPPGY G +CE D+ +CS  ++C NGG CVD VN+++C C   GYTGA C+   + C 
Sbjct: 870  CTCPPGYGGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCL 927

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                L G GVC   + GF C C  +  G
Sbjct: 928  SRPCLHG-GVCSAAHPGFRCTCLESFTG 954



 Score = 88.2 bits (209), Expect = 2e-17
 Identities = 36/89 (40%), Positives = 52/89 (58%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C+CP G+ G  C+ DVDEC+G A C   G C +   +++C C   GYTG  C+ ++N+C
Sbjct: 755  VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG-GYTGPSCDQDINDC 813

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +  L G G C D  G F C+C P   G
Sbjct: 814  DPNPCLNG-GSCQDGVGSFSCSCLPGFAG 841



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 42/95 (44%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C C PGY G NCE DVDEC+ +  C +GG C+D V  Y C C   G  G  CE N ++C
Sbjct: 1067 MCECLPGYNGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSC-PPGTLGVLCEINEDDC 1124

Query: 434  EEDRAL-----CGH-GVCYDTYGGFVCACQPATPG 520
                 L     C H G C D  GGF C C P   G
Sbjct: 1125 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1159



 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE D+DEC  ++ C+NGG C D VN ++C C  +G++G+ C+ +V+EC 
Sbjct: 415 CICMAGFTGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLDVDECA 472

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGS 523
                C +G  C D   G+ C C     G+
Sbjct: 473 S--TPCRNGAKCVDQPDGYECRCAEGFEGT 500



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC+CPPGY GR+C +DVDEC     C +GG C++   ++ C C A GYTG  CE     C
Sbjct: 103 LCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA-GYTGPLCENPAVPC 161

Query: 434 EEDRALCGHGVCYDTYG-GFVCACQPATPG 520
                  G G C  +    + CAC P   G
Sbjct: 162 APSPCRNG-GTCRQSGDLTYDCACLPGFEG 190



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 37/89 (41%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G TG +CE +VD C  A  C +GG C   +  Y C+C   GY G  CE +V+EC 
Sbjct: 1030 CVCPEGRTGSHCEQEVDPCL-AQPCQHGGTCRGYMGGYMCEC-LPGYNGDNCEDDVDECA 1087

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                 C H G C D    ++C+C P T G
Sbjct: 1088 SQP--CQHGGSCIDLVARYLCSCPPGTLG 1114



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C  +++EC+ ++ C  GG CVD  N + C C   G     C    + C 
Sbjct: 603 CVCQPGFTGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPP-GSLPPLCLPPSHPCA 660

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+CYD  GGF C C+P   G
Sbjct: 661 HEP--CSHGICYDAPGGFRCVCEPGWSG 686



 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 36/88 (40%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CP G TG NCE ++D+C+        G C D +N Y C C   G+TG  C   +NEC
Sbjct: 565 LCRCPSGTTGVNCEVNIDDCASNPCTF--GVCRDGINRYDCVC-QPGFTGPLCNVEINEC 621

Query: 434 EEDRALCGH-GVCYDTYGGFVCACQPAT 514
               + CG  G C D   GF C C P +
Sbjct: 622 AS--SPCGEGGSCVDGENGFRCLCPPGS 647



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/87 (39%), Positives = 43/87 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C +   DPC S+ C HGARC     G + C CPPGY G  C  +V  
Sbjct: 64  FSCRCPRGFRGPDCSLP--DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV-- 119

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D   V  PCR+ G+C   PG      P
Sbjct: 120 DECRVGEPCRHGGTCLNTPGSFRCQCP 146



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C PG+ G  C  DVDEC  +  C   G C D V ++TC C   GY G  CE ++ +C 
Sbjct: 833  CSCLPGFAGPRCARDVDECL-SNPC-GPGTCTDHVASFTCTC-PPGYGGFHCEQDLPDCS 889

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G G C D    F C C+P   G+
Sbjct: 890  PSSCFNG-GTCVDGVNSFSCLCRPGYTGA 917



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/81 (40%), Positives = 44/81 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +TG  CEVD  D C S+ C +G  C +   G +SC CP G+ G+ C+L+V  
Sbjct: 413 FTCICMAGFTGTYCEVDI-DECQSSPCVNGGVCKDRVNG-FSCTCPSGFSGSTCQLDVD- 469

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C + PCRN   C   P G
Sbjct: 470 --ECASTPCRNGAKCVDQPDG 488



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
            Y C C   Y G+NCE D  D CAS  C+HG  C+ D    Y C CPPG  G  CE+   +
Sbjct: 1066 YMCECLPGYNGDNCEDDV-DECASQPCQHGGSCI-DLVARYLCSCPPGTLGVLCEINEDD 1123

Query: 174  VSLDPLCVAGP-CRNNGSCSVPPGGDTYSAP 263
                P   +GP C +NG+C    GG   + P
Sbjct: 1124 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1154



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 37/90 (41%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCETNVNEC 433
           CTCPPG  GR CE  +  C+    C +GGRC  A      C C   G+ G RC+ +V+EC
Sbjct: 718 CTCPPGVQGRQCEL-LSPCT-PNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRCQQDVDEC 774

Query: 434 EEDRALCG-HGVCYDTYGGFVCACQPATPG 520
               A CG HG+C +  G F C C     G
Sbjct: 775 -AGPAPCGPHGICTNLAGSFSCTCHGGYTG 803



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   + G  C+ +  D C+   C HG RCV DG   +SC C PGY GT CE +V  
Sbjct: 489 YECRCAEGFEGTLCDRNVDD-CSPDPCHHG-RCV-DGIASFSCACAPGYTGTRCESQVD- 544

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G C
Sbjct: 545 --ECRSQPCRHGGKC 557



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/85 (37%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  CE D  + C S  CR+ A C+ D  G ++C C  G+ GTYCE+++    
Sbjct: 377 CQCGRGYTGPRCETDVNE-CLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCEVDID--- 431

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C + PC N G C     G + + P
Sbjct: 432 ECQSSPCVNGGVCKDRVNGFSCTCP 456



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C   ++G  C    A D C S  CR G  C  DG G + C CPPG  G  CEL   
Sbjct: 676 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCEL--- 731

Query: 180 LDPLCVAGPCRNNGSCSVPPG 242
           L P C   PC + G C   PG
Sbjct: 732 LSP-CTPNPCEHGGRCESAPG 751



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y G +CE D  D C+ ++C +G  CV DG   +SC C PGY G +C+ E   
Sbjct: 868  FTCTCPPGYGGFHCEQDLPD-CSPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHEA-- 923

Query: 183  DPLCVAGPCRNNGSCSVP-PG 242
            DP C++ PC + G CS   PG
Sbjct: 924  DP-CLSRPCLHGGVCSAAHPG 943



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/73 (41%), Positives = 41/73 (56%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C    TG++CE +  DPC +  C+HG  C     G Y C+C PGY+G  CE +V    
Sbjct: 1030 CVCPEGRTGSHCEQEV-DPCLAQPCQHGGTC-RGYMGGYMCECLPGYNGDNCEDDVD--- 1084

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1085 ECASQPCQHGGSC 1097



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNE 430
            CTCPPGYTG  CE D++EC SGA    +   C+ D    + C C A G++G RC+T ++ 
Sbjct: 1151 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSP 1209

Query: 431  CEEDRALCGH-GVCYDT---YGGFVCACQPATP 517
            CE     C H G C  +    GG    C  A P
Sbjct: 1210 CESQP--CQHGGQCRPSPGPGGGLTFTCHCAQP 1240



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/85 (41%), Positives = 44/85 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A YTG  CE  A  PCA + CR+G  C + G   Y C C PG+ G  CE+ V  
Sbjct: 141 FRCQCPAGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD- 198

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C N G+C    G +TY+
Sbjct: 199 D--CPGHRCLNGGTC--VDGVNTYN 219



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CPPG++GR C+     C  AAA         C  GG+CVD  +++ C C   G TG+ 
Sbjct: 982  CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC-PEGRTGSH 1040

Query: 410  CETNVNECEEDRALCGH-GVCYDTYGGFVCACQPATPG 520
            CE  V+ C      C H G C    GG++C C P   G
Sbjct: 1041 CEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNG 1076



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G NCEV+  D C    C +G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 180 YDCACLPGFEGQNCEVNVDD-CPGHRCLNGGTCV-DGVNTYNCQCPPEWTGQFCTEDVDE 237

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L     C N G+C    GG
Sbjct: 238 CQL-QPNACHNGGTCFNTLGG 257



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/75 (42%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C +  TG NCEV+  D CAS  C  G  C  DG   Y C C PG+ G  C +E++ 
Sbjct: 564 YLCRCPSGTTGVNCEVNIDD-CASNPCTFGV-C-RDGINRYDCVCQPGFTGPLCNVEIN- 619

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC   GSC
Sbjct: 620 --ECASSPCGEGGSC 632



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 28/73 (38%), Positives = 33/73 (45%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C  D  +      CRHG  C+    G + C CP GY G  CE      P
Sbjct: 104 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAV--P 160

Query: 189 LCVAGPCRNNGSC 227
            C   PCRN G+C
Sbjct: 161 -CAPSPCRNGGTC 172



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C   +TG  C+ D  D C+  A  C H  RCV   +G + C C  GY G  CE +V+ 
Sbjct: 337 CTCPPGFTGGACDQDV-DECSIGANPCEHLGRCVNT-QGSFLCQCGRGYTGPRCETDVN- 393

Query: 183 DPLCVAGPCRNNGSC 227
              C++GPCRN  +C
Sbjct: 394 --ECLSGPCRNQATC 406



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACR--HGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            + C C   YTG  CE D  + C S AC   H   C++D  G + C C  G+ G  C  + 
Sbjct: 1149 FRCTCPPGYTGLRCEADINE-CRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC--QT 1205

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
             L P C + PC++ G C   PG
Sbjct: 1206 VLSP-CESQPCQHGGQCRPSPG 1226



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            + C C   YTG +C+ D  D C    C +G  C +DG G +SC C PG+ G  C  +V  
Sbjct: 793  FSCTCHGGYTGPSCDQDIND-CDPNPCLNGGSC-QDGVGSFSCSCLPGFAGPRCARDVDE 850

Query: 180  -LDPLCVAGPCRN---NGSCSVPPG 242
             L   C  G C +   + +C+ PPG
Sbjct: 851  CLSNPCGPGTCTDHVASFTCTCPPG 875



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/79 (36%), Positives = 37/79 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG +C  +  D CA+A C HGA C  D    + C CP G  G  C L    
Sbjct: 258 HSCVCVNGWTGESCSQNIDD-CATAVCFHGATC-HDRVASFYCACPMGKTGLLCHL---- 311

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           D  CV+ PC  +  C   P
Sbjct: 312 DDACVSNPCHEDAICDTNP 330



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           + C C   YTG  CE    D C S  CRHG +C+ D    Y C CP G  G  CE+ +  
Sbjct: 526 FSCACAPGYTGTRCESQV-DECRSQPCRHGGKCL-DLVDKYLCRCPSGTTGVNCEVNIDD 583

Query: 180 -LDPLCVAGPCR---NNGSCSVPPG 242
                C  G CR   N   C   PG
Sbjct: 584 CASNPCTFGVCRDGINRYDCVCQPG 608



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC---VEDGRGDYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+++  DPC S  C     C   V  G   +SC CP G+ G  C L   
Sbjct: 25  CLCPPGWVGERCQLE--DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-- 80

Query: 180 LDPLCVAGPCRNNGSCSVPPGG 245
            DP C++ PC +   CSV P G
Sbjct: 81  -DP-CLSSPCAHGARCSVGPDG 100



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN----V 424
           C C  G+TG +C  ++D+C+  A C +G  C D V ++ C C   G TG  C  +     
Sbjct: 260 CVCVNGWTGESCSQNIDDCA-TAVCFHGATCHDRVASFYCAC-PMGKTGLLCHLDDACVS 317

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           N C ED A+C         G  +C C P   G
Sbjct: 318 NPCHED-AICDTN---PVNGRAICTCPPGFTG 345



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 33/81 (40%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C V+  + CAS+ C  G  CV DG   + C CPPG     C L  S 
Sbjct: 601 YDCVCQPGFTGPLCNVEINE-CASSPCGEGGSCV-DGENGFRCLCPPGSLPPLC-LPPS- 656

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
            P C   PC ++G C   PGG
Sbjct: 657 HP-CAHEPC-SHGICYDAPGG 675



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   YTG +C+ +A DPC S  C HG  C     G + C C   + G  C+   +L
Sbjct: 906  FSCLCRPGYTGAHCQHEA-DPCLSRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQ---TL 960

Query: 183  DPLCVAGPCRNNGSC 227
               C   PC+N G C
Sbjct: 961  VDWCSRQPCQNGGRC 975



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 10/89 (11%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            C C   ++G  C++ +  PC  AA          C+ G +CV++    Y C CP G  G+
Sbjct: 982  CLCPPGWSGRLCDIRSL-PCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-CVCPEGRTGS 1039

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            +CE EV  DP C+A PC++ G+C    GG
Sbjct: 1040 HCEQEV--DP-CLAQPCQHGGTCRGYMGG 1065



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 27/75 (36%), Positives = 35/75 (46%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  D  D C S  C  G  C  D    ++C CPPGY G +CE ++  
Sbjct: 831  FSCSCLPGFAGPRCARDV-DECLSNPCGPGT-CT-DHVASFTCTCPPGYGGFHCEQDL-- 885

Query: 183  DPLCVAGPCRNNGSC 227
             P C    C N G+C
Sbjct: 886  -PDCSPSSCFNGGTC 899



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + CHC   + G  CE  A   C    C  G  C +  RG   C CPPG  G  C      
Sbjct: 1233 FTCHCAQPFWGPRCERVARS-CRELQCPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGS 1290

Query: 183  DP-----LCVAGPCRNNGSCSVPP 239
             P      C A PC + GSC   P
Sbjct: 1291 PPGASNASCAAAPCLHGGSCRPAP 1314



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC   +TG  C+T VD CS    C NGGRCV       C C   G++G  C+     C 
Sbjct: 946  CTCLESFTGPQCQTLVDWCS-RQPCQNGGRCVQ--TGAYCLC-PPGWSGRLCDIRSLPCR 1001

Query: 437  EDRA--------LC-GHGVCYDTYGGFVCACQPATPGS 523
            E  A        LC   G C D      C C     GS
Sbjct: 1002 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGS 1039



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS-CDCPPGYHGTYCELEVS 179
           + C C     G  CE+ +  PC    C HG RC E   G    C CP G+ G  C+ +V 
Sbjct: 716 FHCTCPPGVQGRQCELLS--PCTPNPCEHGGRC-ESAPGQLPVCSCPQGWQGPRCQQDV- 771

Query: 180 LDPLCVAGPCRNNGSCS 230
            D      PC  +G C+
Sbjct: 772 -DECAGPAPCGPHGICT 787



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-----GDYSCDCPPGYHGTYCE 167
            Y C C     G  CE++  D         G RC+ +G      G + C CPPGY G  CE
Sbjct: 1104 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1163

Query: 168  LEVSLDPLCVAGPCR--NNGSCSVPPGG 245
             +++    C +G C   +   C   PGG
Sbjct: 1164 ADIN---ECRSGACHAAHTRDCLQDPGG 1188



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
 Frame = +3

Query: 63  PCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           PC   + C +G RC +    + +C CPPG+ G  C+LE   DP C +GPC   G C
Sbjct: 2   PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE---DP-CHSGPCAGRGVC 53



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 23/56 (41%), Positives = 29/56 (51%)
 Frame = +3

Query: 63  PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           PCA   C HG  C  D  G + C C PG+ G  C   ++ D  C + PCR  G+CS
Sbjct: 658 PCAHEPCSHGI-CY-DAPGGFRCVCEPGWSGPRCSQSLARD-ACESQPCRAGGTCS 710



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 10/111 (9%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSG-------AAACLNGGRCVDA--VNNY 370
            +Q  R PR     C CPPG +G +C +      G       AA CL+GG C  A     +
Sbjct: 1265 QQTPRGPR-----CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF 1319

Query: 371  TCDCTATGYTGARCETNVNECE-EDRALCGHGVCYDTYGGFVCACQPATPG 520
             C C A G+TG RCE      E  +   C    C    G   C  +  +PG
Sbjct: 1320 RCAC-AQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG 1369



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAV----NNYTCDCTATGYTGARC 412
           R   C CPPG+ G  C+ + D C  +  C   G C  +V      ++C C   G+ G  C
Sbjct: 21  REAACLCPPGWVGERCQLE-DPCH-SGPCAGRGVCQSSVVAGTARFSCRC-PRGFRGPDC 77

Query: 413 ETNVNECEEDRALCGHGV-C-YDTYGGFVCACQPATPG 520
               + C    + C HG  C     G F+C+C P   G
Sbjct: 78  SL-PDPCLS--SPCAHGARCSVGPDGRFLCSCPPGYQG 112



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC +G  C  +  G +SC C  G+ G  C   +
Sbjct: 218 YNCQCPPEWTGQFCTEDV-DECQLQPNACHNGGTCF-NTLGGHSCVCVNGWTGESCSQNI 275

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C +  +C
Sbjct: 276 D-D--CATAVCFHGATC 289



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDV--DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           C C PG++G  C   +  D C  +  C  GG C      + C C   G  G +CE  ++ 
Sbjct: 678 CVCEPGWSGPRCSQSLARDACE-SQPCRAGGTCSSDGMGFHCTC-PPGVQGRQCEL-LSP 734

Query: 431 CEEDRALCGH-GVCYDTYGGF-VCACQPATPG 520
           C  +   C H G C    G   VC+C     G
Sbjct: 735 CTPNP--CEHGGRCESAPGQLPVCSCPQGWQG 764



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD--CPP---GYHGTYCE 167
            + C C   +TG  CE  A  P  S   R      +  RGD  CD  C     G+ G  C 
Sbjct: 1319 FRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCS 1378

Query: 168  LEVSLDP--LCVAGPC---RNNGSC 227
            L V  DP   C A  C    NN  C
Sbjct: 1379 LSVG-DPWRQCEALQCWRLFNNSRC 1402



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 4/68 (5%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTY--- 481
           C   + C NGGRC    +         G+ G RC+   + C       G GVC  +    
Sbjct: 3   CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSG-PCAGRGVCQSSVVAG 60

Query: 482 -GGFVCAC 502
              F C C
Sbjct: 61  TARFSCRC 68



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +3

Query: 573 ACVEEGGGFRCVCARGYLPPL 635
           +CV+   GFRC+C  G LPPL
Sbjct: 631 SCVDGENGFRCLCPPGSLPPL 651


>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
           protein.
          Length = 1289

 Score = 95.9 bits (228), Expect = 1e-19
 Identities = 43/94 (45%), Positives = 54/94 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP G++G  C+ DVDEC+ +  C NG +CVD  + Y C C A G+ G  C+ NV++C 
Sbjct: 496 CTCPSGFSGSTCQLDVDECA-STPCRNGAKCVDQPDGYECRC-AEGFEGTLCDRNVDDCS 553

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
            D   C HG C D    F CAC    PG T T C
Sbjct: 554 PDP--CHHGRCVDGIASFSCAC---APGYTGTRC 582



 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 47/102 (46%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
           P     +CTCPPG+TG  C+ DVDECS GA  C + GRCV+   ++ C C   GYTG RC
Sbjct: 373 PVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGPRC 431

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
           ET+VNEC           C D  G F C C     G T T C
Sbjct: 432 ETDVNECLSGPCR-NQATCLDRIGQFTCICM---AGFTGTYC 469



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 40/93 (43%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NCE +VD+C G   CLNGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 225 CACLPGFEGQNCEVNVDDCPG-HRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQ 282

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
                C + G C++T GG  C C     G + +
Sbjct: 283 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 315



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/88 (44%), Positives = 51/88 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  CE+ VDEC  +  C +GG+C+D V+ Y C C  +G TG  CE N+++C 
Sbjct: 571 CACAPGYTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRC-PSGTTGVNCEVNIDDCA 628

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C  GVC D    + C CQP   G
Sbjct: 629 SNP--CTFGVCRDGINRYDCVCQPGFTG 654



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 41/91 (45%), Positives = 52/91 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GYTG  CETDV+EC  +  C N   C+D +  +TC C A G+TG  CE +++EC
Sbjct: 419 LCQCGRGYTGPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMA-GFTGTYCEVDIDEC 476

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           +    + G GVC D   GF C C     GST
Sbjct: 477 QSSPCVNG-GVCKDRVNGFSCTCPSGFSGST 506



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 41/88 (46%), Positives = 53/88 (60%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPPGY G +CE D+ +CS  ++C NGG CVD VN+++C C   GYTGA C+   + C 
Sbjct: 861  CTCPPGYGGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCL 918

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                L G GVC   + GF C C  +  G
Sbjct: 919  SRPCLHG-GVCSAAHPGFRCTCLESFTG 945



 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 42/95 (44%), Positives = 49/95 (51%), Gaps = 6/95 (6%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C C PGY G NCE DVDEC+ +  C +GG C+D V  Y C C   G  G  CE N ++C
Sbjct: 1058 MCECLPGYNGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSC-PPGTLGVLCEINEDDC 1115

Query: 434  EEDRAL-----CGH-GVCYDTYGGFVCACQPATPG 520
                 L     C H G C D  GGF C C P   G
Sbjct: 1116 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1150



 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE D+DEC  ++ C+NGG C D VN ++C C  +G++G+ C+ +V+EC 
Sbjct: 458 CICMAGFTGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLDVDECA 515

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGS 523
                C +G  C D   G+ C C     G+
Sbjct: 516 S--TPCRNGAKCVDQPDGYECRCAEGFEGT 543



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC+CPPGY GR+C +DVDEC     C +GG C++   ++ C C A GYTG  CE     C
Sbjct: 146 LCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA-GYTGPLCENPAVPC 204

Query: 434 EEDRALCGHGVCYDTYG-GFVCACQPATPG 520
                  G G C  +    + CAC P   G
Sbjct: 205 APSPCRNG-GTCRQSGDLTYDCACLPGFEG 233



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 37/89 (41%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G TG +CE +VD C  A  C +GG C   +  Y C+C   GY G  CE +V+EC 
Sbjct: 1021 CVCPEGRTGSHCEQEVDPCL-AQPCQHGGTCRGYMGGYMCEC-LPGYNGDNCEDDVDECA 1078

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                 C H G C D    ++C+C P T G
Sbjct: 1079 SQP--CQHGGSCIDLVARYLCSCPPGTLG 1105



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C  +++EC+ ++ C  GG CVD  N + C C   G     C    + C 
Sbjct: 646 CVCQPGFTGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPP-GSLPPLCLPPSHPCA 703

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +   C HG+CYD  GGF C C+P   G
Sbjct: 704 HEP--CSHGICYDAPGGFRCVCEPGWSG 729



 Score = 76.6 bits (180), Expect = 7e-14
 Identities = 36/88 (40%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CP G TG NCE ++D+C+        G C D +N Y C C   G+TG  C   +NEC
Sbjct: 608 LCRCPSGTTGVNCEVNIDDCASNPCTF--GVCRDGINRYDCVC-QPGFTGPLCNVEINEC 664

Query: 434 EEDRALCGH-GVCYDTYGGFVCACQPAT 514
               + CG  G C D   GF C C P +
Sbjct: 665 AS--SPCGEGGSCVDGENGFRCLCPPGS 690



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/87 (39%), Positives = 43/87 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C +   DPC S+ C HGARC     G + C CPPGY G  C  +V  
Sbjct: 107 FSCRCPRGFRGPDCSLP--DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV-- 162

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D   V  PCR+ G+C   PG      P
Sbjct: 163 DECRVGEPCRHGGTCLNTPGSFRCQCP 189



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 34/89 (38%), Positives = 44/89 (49%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C PG+ G  C  DVDEC  +  C   G C D V ++TC C   GY G  CE ++ +C 
Sbjct: 824  CSCLPGFAGPRCARDVDECL-SNPC-GPGTCTDHVASFTCTC-PPGYGGFHCEQDLPDCS 880

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G G C D    F C C+P   G+
Sbjct: 881  PSSCFNG-GTCVDGVNSFSCLCRPGYTGA 908



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/81 (40%), Positives = 44/81 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +TG  CEVD  D C S+ C +G  C +   G +SC CP G+ G+ C+L+V  
Sbjct: 456 FTCICMAGFTGTYCEVDI-DECQSSPCVNGGVCKDRVNG-FSCTCPSGFSGSTCQLDVD- 512

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C + PCRN   C   P G
Sbjct: 513 --ECASTPCRNGAKCVDQPDG 531



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---E 173
            Y C C   Y G+NCE D  D CAS  C+HG  C+ D    Y C CPPG  G  CE+   +
Sbjct: 1057 YMCECLPGYNGDNCEDDV-DECASQPCQHGGSCI-DLVARYLCSCPPGTLGVLCEINEDD 1114

Query: 174  VSLDPLCVAGP-CRNNGSCSVPPGGDTYSAP 263
                P   +GP C +NG+C    GG   + P
Sbjct: 1115 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1145



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   + G  C+ +  D C+   C HG RCV DG   +SC C PGY GT CE +V  
Sbjct: 532 YECRCAEGFEGTLCDRNVDD-CSPDPCHHG-RCV-DGIASFSCACAPGYTGTRCESQVD- 587

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G C
Sbjct: 588 --ECRSQPCRHGGKC 600



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/85 (37%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  CE D  + C S  CR+ A C+ D  G ++C C  G+ GTYCE+++    
Sbjct: 420 CQCGRGYTGPRCETDVNE-CLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCEVDID--- 474

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C + PC N G C     G + + P
Sbjct: 475 ECQSSPCVNGGVCKDRVNGFSCTCP 499



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C   ++G  C    A D C S  CR G  C  DG G + C CPPG  G  CEL   
Sbjct: 719 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCEL--- 774

Query: 180 LDPLCVAGPCRNNGSCSVPPG 242
           L P C   PC + G C   PG
Sbjct: 775 LSP-CTPNPCEHGGRCESAPG 794



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y G +CE D  D C+ ++C +G  CV DG   +SC C PGY G +C+ E   
Sbjct: 859  FTCTCPPGYGGFHCEQDLPD-CSPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHEA-- 914

Query: 183  DPLCVAGPCRNNGSCSVP-PG 242
            DP C++ PC + G CS   PG
Sbjct: 915  DP-CLSRPCLHGGVCSAAHPG 934



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/73 (41%), Positives = 41/73 (56%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C    TG++CE +  DPC +  C+HG  C     G Y C+C PGY+G  CE +V    
Sbjct: 1021 CVCPEGRTGSHCEQEV-DPCLAQPCQHGGTC-RGYMGGYMCECLPGYNGDNCEDDVD--- 1075

Query: 189  LCVAGPCRNNGSC 227
             C + PC++ GSC
Sbjct: 1076 ECASQPCQHGGSC 1088



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNE 430
            CTCPPGYTG  CE D++EC SGA    +   C+ D    + C C A G++G RC+T ++ 
Sbjct: 1142 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSP 1200

Query: 431  CEEDRALCGH-GVCYDT---YGGFVCACQPATP 517
            CE     C H G C  +    GG    C  A P
Sbjct: 1201 CESQP--CQHGGQCRPSPGPGGGLTFTCHCAQP 1231



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/85 (41%), Positives = 44/85 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A YTG  CE  A  PCA + CR+G  C + G   Y C C PG+ G  CE+ V  
Sbjct: 184 FRCQCPAGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD- 241

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C N G+C    G +TY+
Sbjct: 242 D--CPGHRCLNGGTC--VDGVNTYN 262



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 24/112 (21%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET----------DVDECSGAAA--------------CLNGGRCVDAVN 364
            CTCPPG  GR CE               C  A                CLNGG C D V 
Sbjct: 761  CTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVG 820

Query: 365  NYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++C C   G+ G RC  +V+EC  +   CG G C D    F C C P   G
Sbjct: 821  SFSCSC-LPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGG 869



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CPPG++GR C+     C  AAA         C  GG+CVD  +++ C C   G TG+ 
Sbjct: 973  CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC-PEGRTGSH 1031

Query: 410  CETNVNECEEDRALCGH-GVCYDTYGGFVCACQPATPG 520
            CE  V+ C      C H G C    GG++C C P   G
Sbjct: 1032 CEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNG 1067



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G NCEV+  D C    C +G  CV DG   Y+C CPP + G +C  +V  
Sbjct: 223 YDCACLPGFEGQNCEVNVDD-CPGHRCLNGGTCV-DGVNTYNCQCPPEWTGQFCTEDVDE 280

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L     C N G+C    GG
Sbjct: 281 CQL-QPNACHNGGTCFNTLGG 300



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 32/75 (42%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C +  TG NCEV+  D CAS  C  G  C  DG   Y C C PG+ G  C +E++ 
Sbjct: 607 YLCRCPSGTTGVNCEVNIDD-CASNPCTFGV-C-RDGINRYDCVCQPGFTGPLCNVEIN- 662

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC   GSC
Sbjct: 663 --ECASSPCGEGGSC 675



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 28/73 (38%), Positives = 33/73 (45%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C  D  +      CRHG  C+    G + C CP GY G  CE      P
Sbjct: 147 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAV--P 203

Query: 189 LCVAGPCRNNGSC 227
            C   PCRN G+C
Sbjct: 204 -CAPSPCRNGGTC 215



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C   +TG  C+ D  D C+  A  C H  RCV   +G + C C  GY G  CE +V+ 
Sbjct: 380 CTCPPGFTGGACDQDV-DECSIGANPCEHLGRCVNT-QGSFLCQCGRGYTGPRCETDVN- 436

Query: 183 DPLCVAGPCRNNGSC 227
              C++GPCRN  +C
Sbjct: 437 --ECLSGPCRNQATC 449



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACR--HGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            + C C   YTG  CE D  + C S AC   H   C++D  G + C C  G+ G  C  + 
Sbjct: 1140 FRCTCPPGYTGLRCEADINE-CRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC--QT 1196

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
             L P C + PC++ G C   PG
Sbjct: 1197 VLSP-CESQPCQHGGQCRPSPG 1217



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 29/79 (36%), Positives = 37/79 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG +C  +  D CA+A C HGA C  D    + C CP G  G  C L    
Sbjct: 301 HSCVCVNGWTGESCSQNIDD-CATAVCFHGATC-HDRVASFYCACPMGKTGLLCHL---- 354

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           D  CV+ PC  +  C   P
Sbjct: 355 DDACVSNPCHEDAICDTNP 373



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           + C C   YTG  CE    D C S  CRHG +C+ D    Y C CP G  G  CE+ +  
Sbjct: 569 FSCACAPGYTGTRCESQV-DECRSQPCRHGGKCL-DLVDKYLCRCPSGTTGVNCEVNIDD 626

Query: 180 -LDPLCVAGPCR---NNGSCSVPPG 242
                C  G CR   N   C   PG
Sbjct: 627 CASNPCTFGVCRDGINRYDCVCQPG 651



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC---VEDGRGDYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+++  DPC S  C     C   V  G   +SC CP G+ G  C L   
Sbjct: 68  CLCPPGWVGERCQLE--DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-- 123

Query: 180 LDPLCVAGPCRNNGSCSVPPGG 245
            DP C++ PC +   CSV P G
Sbjct: 124 -DP-CLSSPCAHGARCSVGPDG 143



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN----V 424
           C C  G+TG +C  ++D+C+  A C +G  C D V ++ C C   G TG  C  +     
Sbjct: 303 CVCVNGWTGESCSQNIDDCA-TAVCFHGATCHDRVASFYCAC-PMGKTGLLCHLDDACVS 360

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           N C ED A+C         G  +C C P   G
Sbjct: 361 NPCHED-AICDTN---PVNGRAICTCPPGFTG 388



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 33/81 (40%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   +TG  C V+  + CAS+ C  G  CV DG   + C CPPG     C L  S 
Sbjct: 644 YDCVCQPGFTGPLCNVEINE-CASSPCGEGGSCV-DGENGFRCLCPPGSLPPLC-LPPS- 699

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
            P C   PC ++G C   PGG
Sbjct: 700 HP-CAHEPC-SHGICYDAPGG 718



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   YTG +C+ +A DPC S  C HG  C     G + C C   + G  C+   +L
Sbjct: 897  FSCLCRPGYTGAHCQHEA-DPCLSRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQ---TL 951

Query: 183  DPLCVAGPCRNNGSC 227
               C   PC+N G C
Sbjct: 952  VDWCSRQPCQNGGRC 966



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 10/89 (11%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYHGT 158
            C C   ++G  C++ +  PC  AA          C+ G +CV++    Y C CP G  G+
Sbjct: 973  CLCPPGWSGRLCDIRSL-PCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-CVCPEGRTGS 1030

Query: 159  YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            +CE EV  DP C+A PC++ G+C    GG
Sbjct: 1031 HCEQEV--DP-CLAQPCQHGGTCRGYMGG 1056



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 27/75 (36%), Positives = 35/75 (46%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  D  D C S  C  G  C  D    ++C CPPGY G +CE ++  
Sbjct: 822  FSCSCLPGFAGPRCARDV-DECLSNPCGPGT-CT-DHVASFTCTCPPGYGGFHCEQDL-- 876

Query: 183  DPLCVAGPCRNNGSC 227
             P C    C N G+C
Sbjct: 877  -PDCSPSSCFNGGTC 890



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 35/98 (35%), Positives = 40/98 (40%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTC   +TG  C+T VD CS    C NGGRCV       C C   G++G  C+     C 
Sbjct: 937  CTCLESFTGPQCQTLVDWCS-RQPCQNGGRCVQ--TGAYCLC-PPGWSGRLCDIRSLPCR 992

Query: 437  EDRA--------LC-GHGVCYDTYGGFVCACQPATPGS 523
            E  A        LC   G C D      C C     GS
Sbjct: 993  EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGS 1030



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           A  PC   + C +G RC +    + +C CPPG+ G  C+LE   DP C +GPC   G C
Sbjct: 42  AAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE---DP-CHSGPCAGRGVC 96



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-----GDYSCDCPPGYHGTYCE 167
            Y C C     G  CE++  D         G RC+ +G      G + C CPPGY G  CE
Sbjct: 1095 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1154

Query: 168  LEVSLDPLCVAGPCR--NNGSCSVPPGG 245
             +++    C +G C   +   C   PGG
Sbjct: 1155 ADIN---ECRSGACHAAHTRDCLQDPGG 1179



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 23/56 (41%), Positives = 29/56 (51%)
 Frame = +3

Query: 63  PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           PCA   C HG  C  D  G + C C PG+ G  C   ++ D  C + PCR  G+CS
Sbjct: 701 PCAHEPCSHGI-CY-DAPGGFRCVCEPGWSGPRCSQSLARD-ACESQPCRAGGTCS 753



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV--NE 430
           C CPPG     C      C+      + G C DA   + C C   G++G RC  ++  + 
Sbjct: 684 CLCPPGSLPPLCLPPSHPCAHEPC--SHGICYDAPGGFRCVCEP-GWSGPRCSQSLARDA 740

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           CE      G G C     GF C C P   G
Sbjct: 741 CESQPCRAG-GTCSSDGMGFHCTCPPGVQG 769



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAV----NNYTCDCTATGYTGARC 412
           R   C CPPG+ G  C+ + D C  +  C   G C  +V      ++C C   G+ G  C
Sbjct: 64  REAACLCPPGWVGERCQLE-DPCH-SGPCAGRGVCQSSVVAGTARFSCRC-PRGFRGPDC 120

Query: 413 ETNVNECEEDRALCGHGV-C-YDTYGGFVCACQPATPG 520
               + C    + C HG  C     G F+C+C P   G
Sbjct: 121 SL-PDPCLS--SPCAHGARCSVGPDGRFLCSCPPGYQG 155



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRN---NGSCSVPPG 242
           C +G  C +DG G +SC C PG+ G  C  +V   L   C  G C +   + +C+ PPG
Sbjct: 809 CLNGGSC-QDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPG 866



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/54 (37%), Positives = 23/54 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            + CHC   + G  CE  A   C    C  G  C +  RG   C CPPG  G  C
Sbjct: 1224 FTCHCAQPFWGPRCERVARS-CRELQCPVGVPCQQTPRGP-RCACPPGLSGPSC 1275



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC +G  C  +  G +SC C  G+ G  C   +
Sbjct: 261 YNCQCPPEWTGQFCTEDV-DECQLQPNACHNGGTCF-NTLGGHSCVCVNGWTGESCSQNI 318

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C +  +C
Sbjct: 319 D-D--CATAVCFHGATC 332



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDV--DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           C C PG++G  C   +  D C  +  C  GG C      + C C   G  G +CE  ++ 
Sbjct: 721 CVCEPGWSGPRCSQSLARDACE-SQPCRAGGTCSSDGMGFHCTC-PPGVQGRQCEL-LSP 777

Query: 431 CEEDRALCGH-GVCYDTYGGF-VCAC 502
           C  +   C H G C    G   VC+C
Sbjct: 778 CTPNP--CEHGGRCESAPGQLPVCSC 801



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/68 (27%), Positives = 25/68 (36%), Gaps = 4/68 (5%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTY--- 481
           C   + C NGGRC    +         G+ G RC+   + C       G GVC  +    
Sbjct: 46  CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSG-PCAGRGVCQSSVVAG 103

Query: 482 -GGFVCAC 502
              F C C
Sbjct: 104 TARFSCRC 111



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 12/21 (57%), Positives = 15/21 (71%)
 Frame = +3

Query: 573 ACVEEGGGFRCVCARGYLPPL 635
           +CV+   GFRC+C  G LPPL
Sbjct: 674 SCVDGENGFRCLCPPGSLPPL 694


>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
           precursor protein.
          Length = 1285

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CE +VDEC+ +A CL+GG C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCEMEVDECA-SAPCLHGGSCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 37/75 (49%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE++  D CASA C HG  C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCEMEV-DECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/89 (40%), Positives = 45/89 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CE  V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCEMEVDECA 151

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L G G C D  G F C C P   G+
Sbjct: 152 SAPCLHG-GSCLDGVGSFRCVCAPGYGGT 179



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 32/75 (42%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE+EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCEMEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + GSC
Sbjct: 149 --ECASAPCLHGGSC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---- 170
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C L    
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRLPVPS 1135

Query: 171  -EVSLDPLCVAG-PC 209
             E SL+  C+ G PC
Sbjct: 1136 KECSLNVTCLDGSPC 1150



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            +EC C   + G  C +      C+ +  C  G+ C E G    +C C  G  G  C++  
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPT 1174

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
               P C A PC N G+C    G
Sbjct: 1175 L--P-CEANPCLNGGTCRAAGG 1193



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV--NE 430
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC   V   E
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRCRLPVPSKE 1137

Query: 431  CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            C  +        C        C+C     G
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAG 1167



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/53 (37%), Positives = 25/53 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+C  G  G+ C+     C  A  CLNGG C  A     C C A  ++G  CE
Sbjct: 1159 CSCLEGLAGQRCQVPTLPCE-ANPCLNGGTCRAAGGVSECICNAR-FSGQFCE 1209



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
           (Drosophila) protein.
          Length = 1285

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CE +VDEC+ +A CL+GG C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCEMEVDECA-SAPCLHGGSCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 37/75 (49%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE++  D CASA C HG  C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCEMEV-DECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/89 (40%), Positives = 45/89 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CE  V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCEMEVDECA 151

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L G G C D  G F C C P   G+
Sbjct: 152 SAPCLHG-GSCLDGVGSFRCVCAPGYGGT 179



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 32/75 (42%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE+EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCEMEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + GSC
Sbjct: 149 --ECASAPCLHGGSC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---- 170
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C L    
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRLPVPS 1135

Query: 171  -EVSLDPLCVAG-PC 209
             E SL+  C+ G PC
Sbjct: 1136 KECSLNVTCLDGSPC 1150



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            +EC C   + G  C +      C+ +  C  G+ C E G    +C C  G  G  C++  
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPT 1174

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
               P C A PC N G+C    G
Sbjct: 1175 L--P-CEANPCLNGGTCRAAGG 1193



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV--NE 430
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC   V   E
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRCRLPVPSKE 1137

Query: 431  CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            C  +        C        C+C     G
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAG 1167



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/53 (37%), Positives = 25/53 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+C  G  G+ C+     C  A  CLNGG C  A     C C A  ++G  CE
Sbjct: 1159 CSCLEGLAGQRCQVPTLPCE-ANPCLNGGTCRAAGGVSECICNAR-FSGQFCE 1209



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
           (Drosophila) protein.
          Length = 1176

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CE +VDEC+ +A CL+GG C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCEMEVDECA-SAPCLHGGSCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 37/75 (49%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE++  D CASA C HG  C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCEMEV-DECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/89 (40%), Positives = 45/89 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CE  V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCEMEVDECA 151

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L G G C D  G F C C P   G+
Sbjct: 152 SAPCLHG-GSCLDGVGSFRCVCAPGYGGT 179



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 32/75 (42%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE+EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCEMEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + GSC
Sbjct: 149 --ECASAPCLHGGSC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 22/54 (40%), Positives = 26/54 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRC 1129



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/60 (38%), Positives = 28/60 (46%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            CA + C H   C  D    ++C C PG+ G  CE  V  DP C + PC   G C   P G
Sbjct: 1060 CAPSPCLHDGAC-RDLFDAFACACGPGWEGPRCEAHV--DP-CHSAPCA-RGRCHTHPDG 1114



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/52 (36%), Positives = 23/52 (44%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRC 1129



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
           (Drosophila) protein.
          Length = 1285

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CE +VDEC+ +A CL+GG C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCEMEVDECA-SAPCLHGGSCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 37/75 (49%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE++  D CASA C HG  C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCEMEV-DECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/89 (40%), Positives = 45/89 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CE  V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCEMEVDECA 151

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L G G C D  G F C C P   G+
Sbjct: 152 SAPCLHG-GSCLDGVGSFRCVCAPGYGGT 179



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 32/75 (42%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE+EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCEMEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + GSC
Sbjct: 149 --ECASAPCLHGGSC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL---- 170
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C L    
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRLPVPS 1135

Query: 171  -EVSLDPLCVAG-PC 209
             E SL+  C+ G PC
Sbjct: 1136 KECSLNVTCLDGSPC 1150



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            +EC C   + G  C +      C+ +  C  G+ C E G    +C C  G  G  C++  
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPT 1174

Query: 177  SLDPLCVAGPCRNNGSCSVPPG 242
               P C A PC N G+C    G
Sbjct: 1175 L--P-CEANPCLNGGTCRAAGG 1193



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV--NE 430
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC   V   E
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRCRLPVPSKE 1137

Query: 431  CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            C  +        C        C+C     G
Sbjct: 1138 CSLNVTCLDGSPCEGGSPAANCSCLEGLAG 1167



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/53 (37%), Positives = 25/53 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+C  G  G+ C+     C  A  CLNGG C  A     C C A  ++G  CE
Sbjct: 1159 CSCLEGLAGQRCQVPTLPCE-ANPCLNGGTCRAAGGVSECICNAR-FSGQFCE 1209



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
           (Drosophila) protein.
          Length = 1176

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CE +VDEC+ +A CL+GG C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCEMEVDECA-SAPCLHGGSCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 81.4 bits (192), Expect = 2e-15
 Identities = 37/75 (49%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE++  D CASA C HG  C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCEMEV-DECASAPCLHGGSCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/89 (40%), Positives = 45/89 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CE  V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCEMEVDECA 151

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L G G C D  G F C C P   G+
Sbjct: 152 SAPCLHG-GSCLDGVGSFRCVCAPGYGGT 179



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 32/75 (42%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE+EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCEMEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + GSC
Sbjct: 149 --ECASAPCLHGGSC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 22/54 (40%), Positives = 26/54 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRC 1129



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/60 (38%), Positives = 28/60 (46%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            CA + C H   C  D    ++C C PG+ G  CE  V  DP C + PC   G C   P G
Sbjct: 1060 CAPSPCLHDGAC-RDLFDAFACACGPGWEGPRCEAHV--DP-CHSAPCA-RGRCHTHPDG 1114



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/52 (36%), Positives = 23/52 (44%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRC 1129



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>AK123000-1|BAC85516.1| 1176|Homo sapiens  3 (HIVEP3).  protein.
          Length = 1176

 Score = 94.3 bits (224), Expect = 3e-19
 Identities = 43/89 (48%), Positives = 53/89 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +C  +VDEC+ +  CLNGG C D  N + C C   GY G  CE +V+EC
Sbjct: 305 LCHCPPGFEGADCGVEVDECA-SRPCLNGGHCQDLPNGFQCHC-PDGYAGPTCEEDVDEC 362

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             D  L G G C DT  G++C C P T G
Sbjct: 363 LSDPCLHG-GTCSDTVAGYICRC-PETWG 389



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 44/97 (45%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY G  CET+VDEC+ +A CL+G  C+D V ++ C C A GY G RC+ +++EC+
Sbjct: 132 CHCPLGYAGVTCETEVDECA-SAPCLHGASCLDGVGSFRCVC-APGYGGTRCQLDLDECQ 189

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGSTATGCRR 544
                C H G C+D   GF C C  A  G   T C R
Sbjct: 190 SQP--CAHGGTCHDLVNGFRCDC--AGTGYEGTHCER 222



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 40/89 (44%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  C+ D+DEC  +  C +GG C D VN + CDC  TGY G  CE  V EC 
Sbjct: 170 CVCAPGYGGTRCQLDLDECQ-SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECA 228

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
              A C H   C +  G F C C P   G
Sbjct: 229 S--APCEHNASCLEGLGSFRCLCWPGYSG 255



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 38/75 (50%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YECHC   Y G  CE +  D CASA C HGA C+ DG G + C C PGY GT C+L+  L
Sbjct: 130 YECHCPLGYAGVTCETEV-DECASAPCLHGASCL-DGVGSFRCVCAPGYGGTRCQLD--L 185

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC + G+C
Sbjct: 186 DE-CQSQPCAHGGTC 199



 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 38/90 (42%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G  CE D+DEC+ +  C +G  C +  + Y C C   GY G  CET V+EC 
Sbjct: 94  CYCVPGFQGPRCELDIDECA-SRPCHHGATCRNLADRYECHC-PLGYAGVTCETEVDECA 151

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGS 523
              A C HG  C D  G F C C P   G+
Sbjct: 152 S--APCLHGASCLDGVGSFRCVCAPGYGGT 179



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 31/75 (41%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C   + G  CE+D  D CAS  C HGA C  +    Y C CP GY G  CE EV  
Sbjct: 92  FRCYCVPGFQGPRCELDI-DECASRPCHHGATC-RNLADRYECHCPLGYAGVTCETEVD- 148

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC +  SC
Sbjct: 149 --ECASAPCLHGASC 161



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    Y G +CE +  + CASA C H A C+E G G + C C PGY G  CE++  
Sbjct: 206 FRCDCAGTGYEGTHCEREVLE-CASAPCEHNASCLE-GLGSFRCLCWPGYSGELCEVD-- 261

Query: 180 LDPLCVAGPCRNNGSC 227
            +  C + PC++ G C
Sbjct: 262 -EDECASSPCQHGGRC 276



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/74 (39%), Positives = 40/74 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           CHC   + G +C V+  D CAS  C +G  C +D    + C CP GY G  CE +V    
Sbjct: 306 CHCPPGFEGADCGVEV-DECASRPCLNGGHC-QDLPNGFQCHCPDGYAGPTCEEDVD--- 360

Query: 189 LCVAGPCRNNGSCS 230
            C++ PC + G+CS
Sbjct: 361 ECLSDPCLHGGTCS 374



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG------------RGDYS------ 128
           + C C   Y+G  CEVD  D CAS+ C+HG RC++               G +S      
Sbjct: 245 FRCLCWPGYSGELCEVDE-DECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAG 303

Query: 129 --CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
             C CPPG+ G  C +EV     C + PC N G C   P G
Sbjct: 304 FLCHCPPGFEGADCGVEVD---ECASRPCLNGGHCQDLPNG 341



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 37/111 (33%), Positives = 47/111 (42%), Gaps = 21/111 (18%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN---------------------NYT 373
           C C PGY+G  CE D DEC+ ++ C +GGRC+   +                      + 
Sbjct: 247 CLCWPGYSGELCEVDEDECA-SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFL 305

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
           C C   G+ GA C   V+EC     L G G C D   GF C C     G T
Sbjct: 306 CHC-PPGFEGADCGVEVDECASRPCLNG-GHCQDLPNGFQCHCPDGYAGPT 354



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 30/59 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           ++CHC   Y G  CE D  D C S  C HG  C +   G Y C CP  + G  C ++++
Sbjct: 342 FQCHCPDGYAGPTCEEDV-DECLSDPCLHGGTCSDTVAG-YICRCPETWGGRDCSVQLT 398



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   GY G +CE +V EC+ +A C +   C++ + ++ C C   GY+G  CE + +EC
Sbjct: 208 CDCAGTGYEGTHCEREVLECA-SAPCEHNASCLEGLGSFRCLCWP-GYSGELCEVDEDEC 265

Query: 434 EEDRALCGHG 463
               + C HG
Sbjct: 266 AS--SPCQHG 273



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR--GDYSCDCPPGYHGTYCELEVS 179
           EC  T    G  C       CA+  C HGA CV  G     + C C PG+ G  CEL++ 
Sbjct: 52  ECQATES-GGYTCGPMEPRGCATQPCHHGALCVPQGPDPNGFRCYCVPGFQGPRCELDID 110

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC +  +C
Sbjct: 111 ---ECASRPCHHGATC 123



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 22/54 (40%), Positives = 26/54 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            + C C   + G  CE    DPC SA C  G RC     G + C CPPG+ G  C
Sbjct: 1078 FACACGPGWEGPRCEAHV-DPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRC 1129



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G +C V     C    C   A C+   E G   Y C CPPG HG +C   
Sbjct: 380 YICRCPETWGGRDCSVQLTG-CQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGG 245
            +   +    P +     SVP GG
Sbjct: 439 TTFS-VMAGSPIQ----ASVPAGG 457



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQ 505
            CL+ G C D  + + C C   G+ G RCE +V+ C    A C  G C+    G F C C 
Sbjct: 1065 CLHDGACRDLFDAFACAC-GPGWEGPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCP 1121

Query: 506  PATPG 520
            P   G
Sbjct: 1122 PGFGG 1126



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 23/60 (38%), Positives = 28/60 (46%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            CA + C H   C  D    ++C C PG+ G  CE  V  DP C + PC   G C   P G
Sbjct: 1060 CAPSPCLHDGAC-RDLFDAFACACGPGWEGPRCEAHV--DP-CHSAPCA-RGRCHTHPDG 1114



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/52 (36%), Positives = 23/52 (44%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C C PG+ G  CE  VD C  +A C  G         + C C   G+ G RC
Sbjct: 1080 CACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFECRC-PPGFGGPRC 1129



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/67 (32%), Positives = 29/67 (43%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYG 484
           D CS    C NGG C+   N++ C C A  +TG  C   +  C     L     C +   
Sbjct: 809 DMCS-PDPCFNGGTCLVTWNDFHCTCPA-NFTGPTCAQQL-WCPGQPCL-PPATCEEVPD 864

Query: 485 GFVCACQ 505
           GFVC  +
Sbjct: 865 GFVCVAE 871



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 20/74 (27%), Positives = 29/74 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP  +TG  C   +  C G   CL    C +  + + C   AT   G     + +   
Sbjct: 831  CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNAS 888

Query: 437  EDRALCGHGVCYDT 478
              R L G  + + T
Sbjct: 889  SGRLLGGLSLAFRT 902



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV----DAVNNYTCDCTATGYTGARCETN 421
           +C CP  + GR+C   +  C G   C     C+      V++Y C C   G  G  C  N
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQG-HTCPLAATCIPIFESGVHSYVCHC-PPGTHGPFCGQN 438



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 12/32 (37%), Positives = 18/32 (56%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C++GG CVD   ++ CDC A  + G  C   +
Sbjct: 614 CVHGGSCVDLWTHFRCDC-ARPHRGPTCADEI 644


>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
          Length = 2444

 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 41/90 (45%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP GYTG  C  DVDECS GA  C + G+C++ + ++ C C   GYTG RCE +VNE
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC-LQGYTGPRCEIDVNE 455

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C  +        C D  G F C C P   G
Sbjct: 456 CVSNPCQ-NDATCLDQIGEFQCMCMPGYEG 484



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 39/89 (43%), Positives = 50/89 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C +++DEC+G   C NGG C D +N +TC C   GY    C + VNEC 
Sbjct: 664 CACEPGYTGSMCNSNIDECAG-NPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECN 721

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +   C HG C D+  G+ C C P   G+
Sbjct: 722 SNP--CVHGACRDSLNGYKCDCDPGWSGT 748



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+NCE ++D+C G   C NGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 243 CACLPGFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNCPCPPE-WTGQYCTEDVDECQ 300

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C++T+GG+ C C
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVC 323



 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 39/89 (43%), Positives = 50/89 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG +CET+++ECS +  C   G C D  N Y C C   G TG  CE N+++C 
Sbjct: 589 CLCRPGYTGHHCETNINECS-SQPCRLRGTCQDPDNAYLCFC-LKGTTGPNCEINLDDCA 646

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
              + C  G C D   G+ CAC+P   GS
Sbjct: 647 S--SPCDSGTCLDKIDGYECACEPGYTGS 673



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 39/97 (40%), Positives = 56/97 (57%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP G++G +CE +  +C+  ++C NGG CVD +N++TC C   G+TG+ C+  VNEC+
Sbjct: 970  CTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLC-PPGFTGSYCQHVVNECD 1027

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRV 547
                L G G C D  G   C C     G T   C+ +
Sbjct: 1028 SRPCLLG-GTCQDGRGLHRCTC---PQGYTGPNCQNL 1060



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 38/89 (42%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GY+GRNCETD+D+C     C NGG C D +N   CDC   G+ G  CE ++NEC 
Sbjct: 894  CHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDC-LPGFRGTFCEEDINECA 951

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
             D   C +G  C D    + C C     G
Sbjct: 952  SDP--CRNGANCTDCVDSYTCTCPAGFSG 978



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G +CE + DEC+ ++ CL+ GRC+D +N + C+C  TG+TG  C+ +V+EC 
Sbjct: 476 CMCMPGYEGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCEC-PTGFTGHLCQYDVDECA 533

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGSTATGC 538
                C +G  C D    + C C   T G T T C
Sbjct: 534 S--TPCKNGAKCLDGPNTYTCVC---TEGYTGTHC 563



 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 38/88 (43%), Positives = 45/88 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG +CE D+DEC     C + G C D V  +TC C   GYTG  CETN+NEC 
Sbjct: 552 CVCTEGYTGTHCEVDIDECD-PDPC-HYGSCKDGVATFTCLC-RPGYTGHHCETNINECS 608

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    ++C C   T G
Sbjct: 609 SQPCRL-RGTCQDPDNAYLCFCLKGTTG 635



 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 34/90 (37%), Positives = 49/90 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G NC+ + +EC  +  C+NGG C D  +   C C   G++G  C+TN+NEC 
Sbjct: 739 CDCDPGWSGTNCDINNNECE-SNPCVNGGTCKDMTSGIVCTC-REGFSGPNCQTNINECA 796

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +  L   G C D   G+ C C     G+T
Sbjct: 797 SNPCL-NKGTCIDDVAGYKCNCLLPYTGAT 825



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGR-CVDAVNNYTCDCTATGYTGARCETNVNEC 433
            CTCPPG+ G  CE DV+EC        G + CV  VN++ C+C A G+TG RCE+ +N C
Sbjct: 1254 CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA-GHTGRRCESVINGC 1312

Query: 434  EEDRALCGH--GVCYDTYGGFVCACQPATPGST 526
            +      G    V  +T  GF+C C     G+T
Sbjct: 1313 KGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 1345



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC A Y+G NCE D  D C    C +G  C  DG     CDC PG+ GT+CE +++ 
Sbjct: 892  YRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCT-DGINTAFCDCLPGFRGTFCEEDIN- 948

Query: 183  DPLCVAGPCRNNGSCS 230
               C + PCRN  +C+
Sbjct: 949  --ECASDPCRNGANCT 962



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/88 (40%), Positives = 43/88 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GYTG  CE  VDECS  + C NG  C D +  Y+C C A GY G  C   ++EC 
Sbjct: 1132 CRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVA-GYHGVNCSEEIDECL 1189

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    + C+C   T G
Sbjct: 1190 SHPCQNG-GTCLDLPNTYKCSCPRGTQG 1216



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/83 (40%), Positives = 48/83 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G TG NCE ++D+C  A++  + G C+D ++ Y C C   GYTG+ C +N++EC
Sbjct: 626 LCFCLKGTTGPNCEINLDDC--ASSPCDSGTCLDKIDGYECAC-EPGYTGSMCNSNIDEC 682

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
             +    G G C D   GF C C
Sbjct: 683 AGNPCHNG-GTCEDGINGFTCRC 704



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 36/87 (41%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C A YTG+ CE D  D C+ + C++GA C  D  G YSC C  GYHG  C  E+  
Sbjct: 1130 HHCRCQAGYTGSYCE-DLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVNCSEEID- 1186

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C++ PC+N G+C   P     S P
Sbjct: 1187 --ECLSHPCQNGGTCLDLPNTYKCSCP 1211



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   YTG  CE+D  + C S  C++ A C+ D  G++ C C PGY G +C  EV+ 
Sbjct: 436 FECQCLQGYTGPRCEIDVNE-CVSNPCQNDATCL-DQIGEFQCMCMPGYEGVHC--EVNT 491

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC +NG C
Sbjct: 492 DE-CASSPCLHNGRC 505



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 35/89 (39%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            ++CTC  G++G NC+T+++EC+ +  CLN G C+D V  Y C+C    YTGA CE  +  
Sbjct: 775  IVCTCREGFSGPNCQTNINECA-SNPCLNKGTCIDDVAGYKCNCLLP-YTGATCEVVLAP 832

Query: 431  CEEDRALCGHGVC--YDTYGGFVCACQPA 511
            C       G G C   + Y  F C C  A
Sbjct: 833  CAPSPCRNG-GECRQSEDYESFSCVCPTA 860



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 39/107 (36%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-------SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+CP G  G +CE +VD+C       S +  C N G CVD V  Y+C C   G+ G RCE
Sbjct: 1208 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC-PPGFVGERCE 1266

Query: 416  TNVNECEEDRA-LCGHGVCYDTYGGFVCACQPATPG----STATGCR 541
             +VNEC  +     G   C      F C C+    G    S   GC+
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 1313



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/75 (41%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG+ C+ D  D CAS  C++GA+C+ DG   Y+C C  GY GT+CE+++  
Sbjct: 512 FQCECPTGFTGHLCQYDV-DECASTPCKNGAKCL-DGPNTYTCVCTEGYTGTHCEVDID- 568

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC + GSC
Sbjct: 569 --ECDPDPC-HYGSC 580



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 33/88 (37%), Positives = 44/88 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+TG  C+  V+EC  +  CL GG C D    + C C   GYTG  C+  V+ C+
Sbjct: 1008 CLCPPGFTGSYCQHVVNECD-SRPCLLGGTCQDGRGLHRCTC-PQGYTGPNCQNLVHWCD 1065

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C+ T+  + C C     G
Sbjct: 1066 SSPCKNG-GKCWQTHTQYRCECPSGWTG 1092



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 37/91 (40%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CP G+TG  C+     C  AA          C +GG CVDA N + C C A GYTG+ 
Sbjct: 1084 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQA-GYTGSY 1142

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE  V+EC       G   C D  GG+ C C
Sbjct: 1143 CEDLVDECSPSPCQNG-ATCTDYLGGYSCKC 1172



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 31/85 (36%), Positives = 47/85 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   Y G +CEV+  D CAS+ C H  RC+ D   ++ C+CP G+ G  C+ +V  
Sbjct: 474 FQCMCMPGYEGVHCEVNT-DECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD- 530

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C + PC+N   C    G +TY+
Sbjct: 531 --ECASTPCKNGAKCL--DGPNTYT 551



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/78 (42%), Positives = 44/78 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C CT  YTG +CEVD  D C    C +G+ C +DG   ++C C PGY G +CE  ++ 
Sbjct: 550 YTCVCTEGYTGTHCEVDI-DECDPDPCHYGS-C-KDGVATFTCLCRPGYTGHHCETNIN- 605

Query: 183 DPLCVAGPCRNNGSCSVP 236
              C + PCR  G+C  P
Sbjct: 606 --ECSSQPCRLRGTCQDP 621



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            Y C C A Y G NC  +  D C S  C++G  C+ D    Y C CP G  G +CE+ V  
Sbjct: 1168 YSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDD 1225

Query: 180  ----LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                +DP+  +  C NNG+C    GG + + P
Sbjct: 1226 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1257



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 32/81 (39%), Positives = 43/81 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   +TG NCE +  D C    C++G  CV DG   Y+C CPP + G YC  +V  
Sbjct: 241 HECACLPGFTGQNCEENIDD-CPGNNCKNGGACV-DGVNTYNCPCPPEWTGQYCTEDVDE 298

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L +   C+N G+C    GG
Sbjct: 299 CQL-MPNACQNGGTCHNTHGG 318



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +3

Query: 3    YECHC-TARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C TA   G  CEVD  + C  + CRHGA C ++  G Y C C  GY G  CE ++ 
Sbjct: 853  FSCVCPTAGAKGQTCEVDINE-CVLSPCRHGASC-QNTHGXYRCHCQAGYSGRNCETDID 910

Query: 180  LDPLCVAGPCRNNGSCS 230
             D  C   PC N GSC+
Sbjct: 911  -D--CRPNPCHNGGSCT 924



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           YEC C   YTG+ C  +  D CA   C +G  C EDG   ++C CP GYH   C  EV  
Sbjct: 662 YECACEPGYTGSMCNSNI-DECAGNPCHNGGTC-EDGINGFTCRCPEGYHDPTCLSEVNE 719

Query: 177 -SLDPLCVAGPCRN--NG-SCSVPPG 242
            + +P CV G CR+  NG  C   PG
Sbjct: 720 CNSNP-CVHGACRDSLNGYKCDCDPG 744



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/79 (37%), Positives = 39/79 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG +C  +  D CASAAC HGA C  D    + C+CP G  G  C     L
Sbjct: 319 YNCVCVNGWTGEDCSENIDD-CASAACFHGATC-HDRVASFYCECPHGRTGLLCH----L 372

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           +  C++ PC    +C   P
Sbjct: 373 NDACISNPCNEGSNCDTNP 391



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN--NYTCDCTATGYTGARCETNVNE 430
            C C   YTG  CE  +  C+  + C NGG C  + +  +++C C   G  G  CE ++NE
Sbjct: 815  CNCLLPYTGATCEVVLAPCA-PSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINE 873

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C    + C HG  C +T+G + C CQ    G
Sbjct: 874  CV--LSPCRHGASCQNTHGXYRCHCQAGYSG 902



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/77 (40%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-DGRGDYSCDCP-PGYHGTYCELEV 176
            Y+C+C   YTG  CEV    PCA + CR+G  C + +    +SC CP  G  G  CE+++
Sbjct: 813  YKCNCLLPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI 871

Query: 177  SLDPLCVAGPCRNNGSC 227
            +    CV  PCR+  SC
Sbjct: 872  N---ECVLSPCRHGASC 885



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C    TG NCE++  D CAS+ C  G  C++   G Y C C PGY G+ C   +  
Sbjct: 625 YLCFCLKGTTGPNCEINL-DDCASSPCDSGT-CLDKIDG-YECACEPGYTGSMCNSNID- 680

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C   PC N G+C     G T   P
Sbjct: 681 --ECAGNPCHNGGTCEDGINGFTCRCP 705



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/75 (38%), Positives = 44/75 (58%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A ++G +CE +  D C  ++C +G  CV DG   ++C CPPG+ G+YC+  V+ 
Sbjct: 968  YTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCV-DGINSFTCLCPPGFTGSYCQHVVN- 1024

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC   G+C
Sbjct: 1025 --ECDSRPCLLGGTC 1037



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
 Frame = +2

Query: 227 QRAPRRRHLLCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           Q  P     +C CPP + G  C  DV+EC      C +GG C + V +Y C C AT +TG
Sbjct: 154 QCLPFEASYICHCPPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRAT-HTG 212

Query: 404 ARCETNVNECEEDRALCGHGVCYDTYG-GFVCACQPATPG 520
             CE     C       G G C  T      CAC P   G
Sbjct: 213 PNCERPYVPCSPSPCQNG-GTCRPTGDVTHECACLPGFTG 251



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A +TG NCE     PC+ + C++G  C   G   + C C PG+ G  CE  +  
Sbjct: 202 YRCVCRATHTGPNCERPYV-PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID- 259

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D  C    C+N G+C    G +TY+ P
Sbjct: 260 D--CPGNNCKNGGAC--VDGVNTYNCP 282



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C C   +TG NCE     CS  + C NGG C    +  + C C   G+TG  CE N+++C
Sbjct: 204 CVCRATHTGPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLP-GFTGQNCEENIDDC 261

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             +    G G C D    + C C P   G   T
Sbjct: 262 PGNNCKNG-GACVDGVNTYNCPCPPEWTGQYCT 293



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE D  + CAS  CR+GA C  D    Y+C CP G+ G +CE   +  P
Sbjct: 932  CDCLPGFRGTFCEEDINE-CASDPCRNGANCT-DCVDSYTCTCPAGFSGIHCE---NNTP 986

Query: 189  LCVAGPCRNNGSC 227
             C    C N G+C
Sbjct: 987  DCTESSCFNGGTC 999



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G +C+    DPCAS  C +G +C+      Y C CPP +HG  C  +V+ 
Sbjct: 125 YKCRCPPGWSGKSCQ--QADPCASNPCANGGQCLPF-EASYICHCPPSFHGPTCRQDVN- 180

Query: 183 DPLCVAGP--CRNNGSC 227
              C   P  CR+ G+C
Sbjct: 181 --ECGQKPRLCRHGGTC 195



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C + YTG  C  D  D C+  A  C H  +C+    G + C C  GY G  CE++V+ 
Sbjct: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVN- 454

Query: 183 DPLCVAGPCRNNGSC 227
              CV+ PC+N+ +C
Sbjct: 455 --ECVSNPCQNDATC 467



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/75 (34%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G  C     + C +  CR+G  C      +Y C CPPG+ G  C+     
Sbjct: 85  YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QA 141

Query: 183 DPLCVAGPCRNNGSC 227
           DP C + PC N G C
Sbjct: 142 DP-CASNPCANGGQC 155



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRG--DYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+    +PC S  C++   C V D RG  DY+C C  G+ G  C     
Sbjct: 46  CVCGGAFVGPRCQDP--NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCL--TP 101

Query: 180 LDPLCVAGPCRNNGSCSV 233
           LD  C+  PCRN G+C +
Sbjct: 102 LDNACLTNPCRNGGTCDL 119



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/83 (36%), Positives = 42/83 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G NC+ +  + CAS  C +   C++D  G Y C+C   Y G  CE  V L P
Sbjct: 777  CTCREGFSGPNCQTNINE-CASNPCLNKGTCIDDVAG-YKCNCLLPYTGATCE--VVLAP 832

Query: 189  LCVAGPCRNNGSCSVPPGGDTYS 257
             C   PCRN G C      +++S
Sbjct: 833  -CAPSPCRNGGECRQSEDYESFS 854



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C+    + C S  C  G  C +DGRG + C CP GY G  C+   +L
Sbjct: 1006 FTCLCPPGFTGSYCQHVVNE-CDSRPCLLGGTC-QDGRGLHRCTCPQGYTGPNCQ---NL 1060

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC+N G C
Sbjct: 1061 VHWCDSSPCKNGGKC 1075



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG +C  ++D+C+ +AAC +G  C D V ++ C+C   G TG  C  N + C 
Sbjct: 321 CVCVNGWTGEDCSENIDDCA-SAACFHGATCHDRVASFYCEC-PHGRTGLLCHLN-DACI 377

Query: 437 EDRALCGHGVCYDT---YGGFVCACQPATPG 520
            +   C  G   DT    G  +C C     G
Sbjct: 378 SNP--CNEGSNCDTNPVNGKAICTCPSGYTG 406



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP G+ G  CE D   C G+  CLNGG C+    + TC C    +TG  C+   
Sbjct: 1331 RGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGP-FTGPECQFPA 1388

Query: 425  NE-CEEDRALCGHGVCYDT 478
            +  C         G C  T
Sbjct: 1389 SSPCLGGNPCYNQGTCEPT 1407



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTGARCETNVNEC 433
           C CP G TG  C  + D C  +  C  G  C     N    CT  +GYTG  C  +V+EC
Sbjct: 359 CECPHGRTGLLCHLN-DACI-SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
                 C H G C +T G F C C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQC 440



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y    C  +  + C S  C HGA C  D    Y CDC PG+ GT C++    
Sbjct: 700 FTCRCPEGYHDPTCLSEVNE-CNSNPCVHGA-C-RDSLNGYKCDCDPGWSGTNCDIN--- 753

Query: 183 DPLCVAGPCRNNGSC 227
           +  C + PC N G+C
Sbjct: 754 NNECESNPCVNGGTC 768



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            Y C C + +TG  C+V +   C  AA          C+HG  CV+ G   + C C  GY 
Sbjct: 1082 YRCECPSGWTGLYCDVPSVS-CEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYT 1139

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+YCE    L   C   PC+N  +C+   GG
Sbjct: 1140 GSYCE---DLVDECSPSPCQNGATCTDYLGG 1167



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAAC--RHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  CE D  + C S  C  R    CV+    D+ C+C  G+ G  CE   
Sbjct: 1252 YSCTCPPGFVGERCEGDVNE-CLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCE--- 1306

Query: 177  SLDPLCVAGPCRNNGSCSV 233
            S+   C   PC+N G+C+V
Sbjct: 1307 SVINGCKGKPCKNGGTCAV 1325



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C+C  G++G  C T +D       C NGG C +  +  Y C C   G++G  C+   + C
Sbjct: 87  CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC-PPGWSGKSCQ-QADPC 144

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C      ++C C P+  G T
Sbjct: 145 ASNPCANG-GQCLPFEASYICHCPPSFHGPT 174



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            + C C   YTG NC+ +    C S+ C++G +C +     Y C+CP G+ G YC++  VS
Sbjct: 1044 HRCTCPQGYTGPNCQ-NLVHWCDSSPCKNGGKCWQT-HTQYRCECPSGWTGLYCDVPSVS 1101

Query: 180  LDPLC------VAGPCRNNGSC 227
             +         VA  C++ G C
Sbjct: 1102 CEVAAQRQGVDVARLCQHGGLC 1123



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD------PCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTY 161
            Y+C C     G +CE++  D      P + S  C +   CV D  G YSC CPPG+ G  
Sbjct: 1206 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGER 1264

Query: 162  CELEVSLDPLCVAGPCRNNGS 224
            CE +V+    C++ PC   G+
Sbjct: 1265 CEGDVN---ECLSNPCDARGT 1282



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
            + C C A +TG  CE    + C    C++G  C       RG + C CP G+ G  CE +
Sbjct: 1292 FHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG-FICKCPAGFEGATCEND 1349

Query: 174  VSLDPLCVAGPCRNNGSCSVPPGGDT 251
                  C +  C N G+C   P   T
Sbjct: 1350 AR---TCGSLRCLNGGTCISGPRSPT 1372



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C  G+ C      G   C CP GY G  C  +V 
Sbjct: 357 FYCECPHGRTGLLCHLN--DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414

Query: 180 LDPLCVAGPCRNNGSC 227
              L  A PC + G C
Sbjct: 415 ECSL-GANPCEHAGKC 429



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC++G  C  +  G Y+C C  G+ G  C   +
Sbjct: 279 YNCPCPPEWTGQYCTEDV-DECQLMPNACQNGGTC-HNTHGGYNCVCVNGWTGEDCSENI 336

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C +  C +  +C
Sbjct: 337 D-D--CASAACFHGATC 350



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGD-YSCDCPPGYHGTYCEL 170
            C C   +TG  C+  A  PC     C +   C        Y C CP  ++G  C +
Sbjct: 1373 CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1428



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           CLNGG+C  A     C C    + G RC+ + N C
Sbjct: 31  CLNGGKCEAANGTEACVC-GGAFVGPRCQ-DPNPC 63


>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 41/90 (45%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP GYTG  C  DVDECS GA  C + G+C++ + ++ C C   GYTG RCE +VNE
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC-LQGYTGPRCEIDVNE 455

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C  +        C D  G F C C P   G
Sbjct: 456 CVSNPCQ-NDATCLDQIGEFQCICMPGYEG 484



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/89 (43%), Positives = 49/89 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C  ++DEC+G   C NGG C D +N +TC C   GY    C + VNEC 
Sbjct: 664 CACEPGYTGSMCNINIDECAG-NPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECN 721

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +   C HG C D+  G+ C C P   G+
Sbjct: 722 SNP--CVHGACRDSLNGYKCDCDPGWSGT 748



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 40/89 (44%), Positives = 52/89 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG +CET+++ECS +  C +GG C D  N Y C C   G TG  CE N+++C 
Sbjct: 589 CLCRPGYTGHHCETNINECS-SQPCRHGGTCQDRDNAYLCFC-LKGTTGPNCEINLDDCA 646

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
              + C  G C D   G+ CAC+P   GS
Sbjct: 647 S--SPCDSGTCLDKIDGYECACEPGYTGS 673



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+NCE ++D+C G   C NGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 243 CACLPGFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNCRCPPE-WTGQYCTEDVDECQ 300

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C++T+GG+ C C
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVC 323



 Score = 90.2 bits (214), Expect = 5e-18
 Identities = 39/97 (40%), Positives = 58/97 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP G++G +CE +  +C+  ++C NGG CVD +N++TC C   G+TG+ C+ +VNEC+
Sbjct: 969  CTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLC-PPGFTGSYCQHDVNECD 1026

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRV 547
                L G G C D  G + C C     G T   C+ +
Sbjct: 1027 SQPCLHG-GTCQDGCGSYRCTC---PQGYTGPNCQNL 1059



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 38/89 (42%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GY+GRNCETD+D+C     C NGG C D +N   CDC   G+ G  CE ++NEC 
Sbjct: 893  CHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDC-LPGFRGTFCEEDINECA 950

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
             D   C +G  C D    + C C     G
Sbjct: 951  SDP--CRNGANCTDCVDSYTCTCPAGFSG 977



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 35/90 (38%), Positives = 50/90 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G NC+ + +EC  +  C+NGG C D  + Y C C   G++G  C+TN+NEC 
Sbjct: 739 CDCDPGWSGTNCDINNNECE-SNPCVNGGTCKDMTSGYVCTC-REGFSGPNCQTNINECA 796

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +  L   G C D   G+ C C     G+T
Sbjct: 797 SNPCL-NQGTCIDDVAGYKCNCLLPYTGAT 825



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G +CE + DEC+ ++ CL+ GRC+D +N + C+C  TG+TG  C+ +V+EC 
Sbjct: 476 CICMPGYEGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCEC-PTGFTGHLCQYDVDECA 533

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGSTATGC 538
                C +G  C D    + C C   T G T T C
Sbjct: 534 S--TPCKNGAKCLDGPNTYTCVC---TEGYTGTHC 563



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 40/89 (44%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG +CE D+DEC     C + G C D V  +TC C   GYTG  CETN+NEC 
Sbjct: 552 CVCTEGYTGTHCEVDIDECD-PDPC-HYGSCKDGVATFTCLC-RPGYTGHHCETNINECS 608

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C D    ++C C   T G
Sbjct: 609 SQP--CRHGGTCQDRDNAYLCFCLKGTTG 635



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 35/88 (39%), Positives = 47/88 (53%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+TG  C+ DV+EC  +  CL+GG C D   +Y C C   GYTG  C+  V+ C+
Sbjct: 1007 CLCPPGFTGSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTC-PQGYTGPNCQNLVHWCD 1064

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C+ T+  + C C     G
Sbjct: 1065 SSPCKNG-GKCWQTHTQYRCECPSGWTG 1091



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGR-CVDAVNNYTCDCTATGYTGARCETNVNEC 433
            CTCPPG+ G  CE DV+EC        G + CV  VN++ C+C A G+TG RCE+ +N C
Sbjct: 1253 CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA-GHTGRRCESVINGC 1311

Query: 434  EEDRALCGH--GVCYDTYGGFVCACQPATPGST 526
            +      G    V  +T  GF+C C     G+T
Sbjct: 1312 KGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 1344



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC A Y+G NCE D  D C    C +G  C  DG     CDC PG+ GT+CE +++ 
Sbjct: 891  YRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCT-DGINTAFCDCLPGFRGTFCEEDIN- 947

Query: 183  DPLCVAGPCRNNGSCS 230
               C + PCRN  +C+
Sbjct: 948  --ECASDPCRNGANCT 961



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/88 (40%), Positives = 43/88 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GYTG  CE  VDECS  + C NG  C D +  Y+C C A GY G  C   ++EC 
Sbjct: 1131 CRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVA-GYHGVNCSEEIDECL 1188

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    + C+C   T G
Sbjct: 1189 SHPCQNG-GTCLDLPNTYKCSCPRGTQG 1215



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 36/87 (41%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C A YTG+ CE D  D C+ + C++GA C  D  G YSC C  GYHG  C  E+  
Sbjct: 1129 HHCRCQAGYTGSYCE-DLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVNCSEEID- 1185

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C++ PC+N G+C   P     S P
Sbjct: 1186 --ECLSHPCQNGGTCLDLPNTYKCSCP 1210



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G TG NCE ++D+C  A++  + G C+D ++ Y C C   GYTG+ C  N++EC
Sbjct: 626 LCFCLKGTTGPNCEINLDDC--ASSPCDSGTCLDKIDGYECAC-EPGYTGSMCNINIDEC 682

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
             +    G G C D   GF C C
Sbjct: 683 AGNPCHNG-GTCEDGINGFTCRC 704



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +CTC  G++G NC+T+++EC+ +  CLN G C+D V  Y C+C    YTGA CE  +  C
Sbjct: 776  VCTCREGFSGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNCLLP-YTGATCEVVLAPC 833

Query: 434  EEDRALCGHGVC--YDTYGGFVCACQPATPGST 526
                   G G C   + Y  F C C     G T
Sbjct: 834  APSPCRNG-GECRQSEDYESFSCVCPTGWQGQT 865



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   YTG  CE+D  + C S  C++ A C+ D  G++ C C PGY G +C  EV+ 
Sbjct: 436 FECQCLQGYTGPRCEIDVNE-CVSNPCQNDATCL-DQIGEFQCICMPGYEGVHC--EVNT 491

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC +NG C
Sbjct: 492 DE-CASSPCLHNGRC 505



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-DGRGDYSCDCPPGYHGTYCELEVS 179
            Y+C+C   YTG  CEV    PCA + CR+G  C + +    +SC CP G+ G  CE++++
Sbjct: 813  YKCNCLLPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871

Query: 180  LDPLCVAGPCRNNGSCSVPPGG 245
                CV  PCR+  SC    GG
Sbjct: 872  ---ECVLSPCRHGASCQNTHGG 890



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/89 (35%), Positives = 46/89 (51%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G+ G+ CE D++EC   + C +G  C +    Y C C A GY+G  CET++++C 
Sbjct: 855  CVCPTGWQGQTCEVDINECV-LSPCRHGASCQNTHGGYRCHCQA-GYSGRNCETDIDDCR 912

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    G G C D      C C P   G+
Sbjct: 913  PNPCHNG-GSCTDGINTAFCDCLPGFRGT 940



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 39/107 (36%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-------SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+CP G  G +CE +VD+C       S +  C N G CVD V  Y+C C   G+ G RCE
Sbjct: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC-PPGFVGERCE 1265

Query: 416  TNVNECEEDRA-LCGHGVCYDTYGGFVCACQPATPG----STATGCR 541
             +VNEC  +     G   C      F C C+    G    S   GC+
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 1312



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/75 (41%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG+ C+ D  D CAS  C++GA+C+ DG   Y+C C  GY GT+CE+++  
Sbjct: 512 FQCECPTGFTGHLCQYDV-DECASTPCKNGAKCL-DGPNTYTCVCTEGYTGTHCEVDID- 568

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC + GSC
Sbjct: 569 --ECDPDPC-HYGSC 580



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 31/76 (40%), Positives = 40/76 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CEVD  + C  + CRHGA C ++  G Y C C  GY G  CE ++  
Sbjct: 853  FSCVCPTGWQGQTCEVDINE-CVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNCETDID- 909

Query: 183  DPLCVAGPCRNNGSCS 230
            D  C   PC N GSC+
Sbjct: 910  D--CRPNPCHNGGSCT 923



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 37/91 (40%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CP G+TG  C+     C  AA          C +GG CVDA N + C C A GYTG+ 
Sbjct: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQA-GYTGSY 1141

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE  V+EC       G   C D  GG+ C C
Sbjct: 1142 CEDLVDECSPSPCQNG-ATCTDYLGGYSCKC 1171



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C CT  YTG +CEVD  D C    C +G+ C +DG   ++C C PGY G +CE  ++ 
Sbjct: 550 YTCVCTEGYTGTHCEVDI-DECDPDPCHYGS-C-KDGVATFTCLCRPGYTGHHCETNIN- 605

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G+C
Sbjct: 606 --ECSSQPCRHGGTC 618



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 37/86 (43%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           YEC C   YTG+ C ++  D CA   C +G  C EDG   ++C CP GYH   C  EV  
Sbjct: 662 YECACEPGYTGSMCNINI-DECAGNPCHNGGTC-EDGINGFTCRCPEGYHDPTCLSEVNE 719

Query: 177 -SLDPLCVAGPCRN--NG-SCSVPPG 242
            + +P CV G CR+  NG  C   PG
Sbjct: 720 CNSNP-CVHGACRDSLNGYKCDCDPG 744



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            Y C C A Y G NC  +  D C S  C++G  C+ D    Y C CP G  G +CE+ V  
Sbjct: 1167 YSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDD 1224

Query: 180  ----LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                +DP+  +  C NNG+C    GG + + P
Sbjct: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 31/85 (36%), Positives = 47/85 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   Y G +CEV+  D CAS+ C H  RC+ D   ++ C+CP G+ G  C+ +V  
Sbjct: 474 FQCICMPGYEGVHCEVNT-DECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD- 530

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C + PC+N   C    G +TY+
Sbjct: 531 --ECASTPCKNGAKCL--DGPNTYT 551



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 30/75 (40%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C+ D  + C S  C HG  C +DG G Y C CP GY G  C+   +L
Sbjct: 1005 FTCLCPPGFTGSYCQHDVNE-CDSQPCLHGGTC-QDGCGSYRCTCPQGYTGPNCQ---NL 1059

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC+N G C
Sbjct: 1060 VHWCDSSPCKNGGKC 1074



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 32/81 (39%), Positives = 43/81 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   +TG NCE +  D C    C++G  CV DG   Y+C CPP + G YC  +V  
Sbjct: 241 HECACLPGFTGQNCEENIDD-CPGNNCKNGGACV-DGVNTYNCRCPPEWTGQYCTEDVDE 298

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L +   C+N G+C    GG
Sbjct: 299 CQL-MPNACQNGGTCHNTHGG 318



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 29/75 (38%), Positives = 46/75 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A ++G +CE +  D C  ++C +G  CV DG   ++C CPPG+ G+YC+ +V+ 
Sbjct: 967  YTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCV-DGINSFTCLCPPGFTGSYCQHDVN- 1023

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC + G+C
Sbjct: 1024 --ECDSQPCLHGGTC 1036



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 42/87 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C    TG NCE++  D CAS+ C  G  C++   G Y C C PGY G+ C + +  
Sbjct: 625 YLCFCLKGTTGPNCEINL-DDCASSPCDSGT-CLDKIDG-YECACEPGYTGSMCNINID- 680

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C   PC N G+C     G T   P
Sbjct: 681 --ECAGNPCHNGGTCEDGINGFTCRCP 705



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/79 (37%), Positives = 39/79 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG +C  +  D CASAAC HGA C  D    + C+CP G  G  C     L
Sbjct: 319 YNCVCVNGWTGEDCSENIDD-CASAACFHGATC-HDRVASFYCECPHGRTGLLCH----L 372

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           +  C++ PC    +C   P
Sbjct: 373 NDACISNPCNEGSNCDTNP 391



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
 Frame = +2

Query: 227 QRAPRRRHLLCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           Q  P     +C CPP + G  C  DV+EC      C +GG C + V +Y C C AT +TG
Sbjct: 154 QCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRAT-HTG 212

Query: 404 ARCETNVNECEEDRALCGHGVCYDTYG-GFVCACQPATPG 520
             CE     C       G G C  T      CAC P   G
Sbjct: 213 PNCERPYVPCSPSPCQNG-GTCRPTGDVTHECACLPGFTG 251



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G +C+    DPCAS  C +G +C+      Y C CPP +HG  C  +V+ 
Sbjct: 125 YKCRCPPGWSGKSCQ--QADPCASNPCANGGQCLPF-EASYICHCPPSFHGPTCRQDVN- 180

Query: 183 DPLCVAGPCRNNGSC 227
           +     G CR+ G+C
Sbjct: 181 ECGQKPGLCRHGGTC 195



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C C   +TG NCE     CS  + C NGG C    +  + C C   G+TG  CE N+++C
Sbjct: 204 CVCRATHTGPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLP-GFTGQNCEENIDDC 261

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             +    G G C D    + C C P   G   T
Sbjct: 262 PGNNCKNG-GACVDGVNTYNCRCPPEWTGQYCT 293



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G NC+ +  + CAS  C +   C++D  G Y C+C   Y G  CE  V L
Sbjct: 775  YVCTCREGFSGPNCQTNINE-CASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCE--VVL 830

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
             P C   PCRN G C      +++S
Sbjct: 831  AP-CAPSPCRNGGECRQSEDYESFS 854



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE D  + CAS  CR+GA C  D    Y+C CP G+ G +CE   +  P
Sbjct: 931  CDCLPGFRGTFCEEDINE-CASDPCRNGANCT-DCVDSYTCTCPAGFSGIHCE---NNTP 985

Query: 189  LCVAGPCRNNGSC 227
             C    C N G+C
Sbjct: 986  DCTESSCFNGGTC 998



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C + YTG  C  D  D C+  A  C H  +C+    G + C C  GY G  CE++V+ 
Sbjct: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVN- 454

Query: 183 DPLCVAGPCRNNGSC 227
              CV+ PC+N+ +C
Sbjct: 455 --ECVSNPCQNDATC 467



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/75 (34%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G  C     + C +  CR+G  C      +Y C CPPG+ G  C+     
Sbjct: 85  YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QA 141

Query: 183 DPLCVAGPCRNNGSC 227
           DP C + PC N G C
Sbjct: 142 DP-CASNPCANGGQC 155



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRG--DYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+    +PC S  C++   C V D RG  DY+C C  G+ G  C     
Sbjct: 46  CVCGGAFVGPRCQDP--NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCL--TP 101

Query: 180 LDPLCVAGPCRNNGSCSV 233
           LD  C+  PCRN G+C +
Sbjct: 102 LDNACLTNPCRNGGTCDL 119



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A +TG NCE     PC+ + C++G  C   G   + C C PG+ G  CE  +  
Sbjct: 202 YRCVCRATHTGPNCERPYV-PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID- 259

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G+C    G +TY+
Sbjct: 260 D--CPGNNCKNGGAC--VDGVNTYN 280



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG +C  ++D+C+ +AAC +G  C D V ++ C+C   G TG  C  N + C 
Sbjct: 321 CVCVNGWTGEDCSENIDDCA-SAACFHGATCHDRVASFYCEC-PHGRTGLLCHLN-DACI 377

Query: 437 EDRALCGHGVCYDT---YGGFVCACQPATPG 520
            +   C  G   DT    G  +C C     G
Sbjct: 378 SNP--CNEGSNCDTNPVNGKAICTCPSGYTG 406



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP G+ G  CE D   C G+  CLNGG C+    + TC C    +TG  C+   
Sbjct: 1330 RGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGP-FTGPECQFPA 1387

Query: 425  NE-CEEDRALCGHGVCYDT 478
            +  C         G C  T
Sbjct: 1388 SSPCLGGNPCYNQGTCEPT 1406



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTGARCETNVNEC 433
           C CP G TG  C  + D C  +  C  G  C     N    CT  +GYTG  C  +V+EC
Sbjct: 359 CECPHGRTGLLCHLN-DACI-SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
                 C H G C +T G F C C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQC 440



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y    C  +  + C S  C HGA C  D    Y CDC PG+ GT C++    
Sbjct: 700 FTCRCPEGYHDPTCLSEVNE-CNSNPCVHGA-C-RDSLNGYKCDCDPGWSGTNCDIN--- 753

Query: 183 DPLCVAGPCRNNGSC 227
           +  C + PC N G+C
Sbjct: 754 NNECESNPCVNGGTC 768



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            Y C C + +TG  C+V +   C  AA          C+HG  CV+ G   + C C  GY 
Sbjct: 1081 YRCECPSGWTGLYCDVPSVS-CEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYT 1138

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+YCE    L   C   PC+N  +C+   GG
Sbjct: 1139 GSYCE---DLVDECSPSPCQNGATCTDYLGG 1166



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+ +    C S+ C++G +C +     Y C+CP G+ G YC++  VS
Sbjct: 1043 YRCTCPQGYTGPNCQ-NLVHWCDSSPCKNGGKCWQT-HTQYRCECPSGWTGLYCDVPSVS 1100

Query: 180  LDPLC------VAGPCRNNGSC 227
             +         VA  C++ G C
Sbjct: 1101 CEVAAQRQGVDVARLCQHGGLC 1122



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAAC--RHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  CE D  + C S  C  R    CV+    D+ C+C  G+ G  CE   
Sbjct: 1251 YSCTCPPGFVGERCEGDVNE-CLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCE--- 1305

Query: 177  SLDPLCVAGPCRNNGSCSV 233
            S+   C   PC+N G+C+V
Sbjct: 1306 SVINGCKGKPCKNGGTCAV 1324



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C+C  G++G  C T +D       C NGG C +  +  Y C C   G++G  C+   + C
Sbjct: 87  CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC-PPGWSGKSCQ-QADPC 144

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C      ++C C P+  G T
Sbjct: 145 ASNPCANG-GQCLPFEASYICHCPPSFHGPT 174



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD------PCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTY 161
            Y+C C     G +CE++  D      P + S  C +   CV D  G YSC CPPG+ G  
Sbjct: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGER 1263

Query: 162  CELEVSLDPLCVAGPCRNNGS 224
            CE +V+    C++ PC   G+
Sbjct: 1264 CEGDVN---ECLSNPCDARGT 1281



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
            + C C A +TG  CE    + C    C++G  C       RG + C CP G+ G  CE +
Sbjct: 1291 FHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG-FICKCPAGFEGATCEND 1348

Query: 174  VSLDPLCVAGPCRNNGSCSVPPGGDT 251
                  C +  C N G+C   P   T
Sbjct: 1349 AR---TCGSLRCLNGGTCISGPRSPT 1371



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C  G+ C      G   C CP GY G  C  +V 
Sbjct: 357 FYCECPHGRTGLLCHLN--DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414

Query: 180 LDPLCVAGPCRNNGSC 227
              L  A PC + G C
Sbjct: 415 ECSL-GANPCEHAGKC 429



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC++G  C  +  G Y+C C  G+ G  C   +
Sbjct: 279 YNCRCPPEWTGQYCTEDV-DECQLMPNACQNGGTC-HNTHGGYNCVCVNGWTGEDCSENI 336

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C +  C +  +C
Sbjct: 337 D-D--CASAACFHGATC 350



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGD-YSCDCPPGYHGTYCEL 170
            C C   +TG  C+  A  PC     C +   C        Y C CP  ++G  C +
Sbjct: 1372 CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           CLNGG+C  A     C C    + G RC+ + N C
Sbjct: 31  CLNGGKCEAANGTEACVC-GGAFVGPRCQ-DPNPC 63


>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 41/90 (45%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP GYTG  C  DVDECS GA  C + G+C++ + ++ C C   GYTG RCE +VNE
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC-LQGYTGPRCEIDVNE 455

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C  +        C D  G F C C P   G
Sbjct: 456 CVSNPCQ-NDATCLDQIGEFQCICMPGYEG 484



 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 39/89 (43%), Positives = 49/89 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C  ++DEC+G   C NGG C D +N +TC C   GY    C + VNEC 
Sbjct: 664 CACEPGYTGSMCNINIDECAG-NPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECN 721

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +   C HG C D+  G+ C C P   G+
Sbjct: 722 SNP--CVHGACRDSLNGYKCDCDPGWSGT 748



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 40/89 (44%), Positives = 52/89 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG +CET+++ECS +  C +GG C D  N Y C C   G TG  CE N+++C 
Sbjct: 589 CLCRPGYTGHHCETNINECS-SQPCRHGGTCQDRDNAYLCFC-LKGTTGPNCEINLDDCA 646

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
              + C  G C D   G+ CAC+P   GS
Sbjct: 647 S--SPCDSGTCLDKIDGYECACEPGYTGS 673



 Score = 90.6 bits (215), Expect = 4e-18
 Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+NCE ++D+C G   C NGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 243 CACLPGFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNCRCPPE-WTGQYCTEDVDECQ 300

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C++T+GG+ C C
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVC 323



 Score = 90.2 bits (214), Expect = 5e-18
 Identities = 39/97 (40%), Positives = 58/97 (59%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP G++G +CE +  +C+  ++C NGG CVD +N++TC C   G+TG+ C+ +VNEC+
Sbjct: 969  CTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLC-PPGFTGSYCQHDVNECD 1026

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRV 547
                L G G C D  G + C C     G T   C+ +
Sbjct: 1027 SQPCLHG-GTCQDGCGSYRCTC---PQGYTGPNCQNL 1059



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 38/89 (42%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GY+GRNCETD+D+C     C NGG C D +N   CDC   G+ G  CE ++NEC 
Sbjct: 893  CHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDC-LPGFRGTFCEEDINECA 950

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
             D   C +G  C D    + C C     G
Sbjct: 951  SDP--CRNGANCTDCVDSYTCTCPAGFSG 977



 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 35/90 (38%), Positives = 50/90 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G NC+ + +EC  +  C+NGG C D  + Y C C   G++G  C+TN+NEC 
Sbjct: 739 CDCDPGWSGTNCDINNNECE-SNPCVNGGTCKDMTSGYVCTC-REGFSGPNCQTNINECA 796

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +  L   G C D   G+ C C     G+T
Sbjct: 797 SNPCL-NQGTCIDDVAGYKCNCLLPYTGAT 825



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G +CE + DEC+ ++ CL+ GRC+D +N + C+C  TG+TG  C+ +V+EC 
Sbjct: 476 CICMPGYEGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCEC-PTGFTGHLCQYDVDECA 533

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGSTATGC 538
                C +G  C D    + C C   T G T T C
Sbjct: 534 S--TPCKNGAKCLDGPNTYTCVC---TEGYTGTHC 563



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 40/89 (44%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG +CE D+DEC     C + G C D V  +TC C   GYTG  CETN+NEC 
Sbjct: 552 CVCTEGYTGTHCEVDIDECD-PDPC-HYGSCKDGVATFTCLC-RPGYTGHHCETNINECS 608

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
                C H G C D    ++C C   T G
Sbjct: 609 SQP--CRHGGTCQDRDNAYLCFCLKGTTG 635



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 35/88 (39%), Positives = 47/88 (53%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+TG  C+ DV+EC  +  CL+GG C D   +Y C C   GYTG  C+  V+ C+
Sbjct: 1007 CLCPPGFTGSYCQHDVNECD-SQPCLHGGTCQDGCGSYRCTC-PQGYTGPNCQNLVHWCD 1064

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C+ T+  + C C     G
Sbjct: 1065 SSPCKNG-GKCWQTHTQYRCECPSGWTG 1091



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGR-CVDAVNNYTCDCTATGYTGARCETNVNEC 433
            CTCPPG+ G  CE DV+EC        G + CV  VN++ C+C A G+TG RCE+ +N C
Sbjct: 1253 CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA-GHTGRRCESVINGC 1311

Query: 434  EEDRALCGH--GVCYDTYGGFVCACQPATPGST 526
            +      G    V  +T  GF+C C     G+T
Sbjct: 1312 KGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 1344



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC A Y+G NCE D  D C    C +G  C  DG     CDC PG+ GT+CE +++ 
Sbjct: 891  YRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCT-DGINTAFCDCLPGFRGTFCEEDIN- 947

Query: 183  DPLCVAGPCRNNGSCS 230
               C + PCRN  +C+
Sbjct: 948  --ECASDPCRNGANCT 961



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/88 (40%), Positives = 43/88 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GYTG  CE  VDECS  + C NG  C D +  Y+C C A GY G  C   ++EC 
Sbjct: 1131 CRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVA-GYHGVNCSEEIDECL 1188

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    + C+C   T G
Sbjct: 1189 SHPCQNG-GTCLDLPNTYKCSCPRGTQG 1215



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 36/87 (41%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C A YTG+ CE D  D C+ + C++GA C  D  G YSC C  GYHG  C  E+  
Sbjct: 1129 HHCRCQAGYTGSYCE-DLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVNCSEEID- 1185

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C++ PC+N G+C   P     S P
Sbjct: 1186 --ECLSHPCQNGGTCLDLPNTYKCSCP 1210



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G TG NCE ++D+C  A++  + G C+D ++ Y C C   GYTG+ C  N++EC
Sbjct: 626 LCFCLKGTTGPNCEINLDDC--ASSPCDSGTCLDKIDGYECAC-EPGYTGSMCNINIDEC 682

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
             +    G G C D   GF C C
Sbjct: 683 AGNPCHNG-GTCEDGINGFTCRC 704



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +CTC  G++G NC+T+++EC+ +  CLN G C+D V  Y C+C    YTGA CE  +  C
Sbjct: 776  VCTCREGFSGPNCQTNINECA-SNPCLNQGTCIDDVAGYKCNCLLP-YTGATCEVVLAPC 833

Query: 434  EEDRALCGHGVC--YDTYGGFVCACQPATPGST 526
                   G G C   + Y  F C C     G T
Sbjct: 834  APSPCRNG-GECRQSEDYESFSCVCPTGWQGQT 865



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   YTG  CE+D  + C S  C++ A C+ D  G++ C C PGY G +C  EV+ 
Sbjct: 436 FECQCLQGYTGPRCEIDVNE-CVSNPCQNDATCL-DQIGEFQCICMPGYEGVHC--EVNT 491

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC +NG C
Sbjct: 492 DE-CASSPCLHNGRC 505



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-DGRGDYSCDCPPGYHGTYCELEVS 179
            Y+C+C   YTG  CEV    PCA + CR+G  C + +    +SC CP G+ G  CE++++
Sbjct: 813  YKCNCLLPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871

Query: 180  LDPLCVAGPCRNNGSCSVPPGG 245
                CV  PCR+  SC    GG
Sbjct: 872  ---ECVLSPCRHGASCQNTHGG 890



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 32/89 (35%), Positives = 46/89 (51%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP G+ G+ CE D++EC   + C +G  C +    Y C C A GY+G  CET++++C 
Sbjct: 855  CVCPTGWQGQTCEVDINECV-LSPCRHGASCQNTHGGYRCHCQA-GYSGRNCETDIDDCR 912

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    G G C D      C C P   G+
Sbjct: 913  PNPCHNG-GSCTDGINTAFCDCLPGFRGT 940



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 39/107 (36%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-------SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+CP G  G +CE +VD+C       S +  C N G CVD V  Y+C C   G+ G RCE
Sbjct: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC-PPGFVGERCE 1265

Query: 416  TNVNECEEDRA-LCGHGVCYDTYGGFVCACQPATPG----STATGCR 541
             +VNEC  +     G   C      F C C+    G    S   GC+
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 1312



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/75 (41%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG+ C+ D  D CAS  C++GA+C+ DG   Y+C C  GY GT+CE+++  
Sbjct: 512 FQCECPTGFTGHLCQYDV-DECASTPCKNGAKCL-DGPNTYTCVCTEGYTGTHCEVDID- 568

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC + GSC
Sbjct: 569 --ECDPDPC-HYGSC 580



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 31/76 (40%), Positives = 40/76 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CEVD  + C  + CRHGA C ++  G Y C C  GY G  CE ++  
Sbjct: 853  FSCVCPTGWQGQTCEVDINE-CVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNCETDID- 909

Query: 183  DPLCVAGPCRNNGSCS 230
            D  C   PC N GSC+
Sbjct: 910  D--CRPNPCHNGGSCT 923



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 37/91 (40%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CP G+TG  C+     C  AA          C +GG CVDA N + C C A GYTG+ 
Sbjct: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQA-GYTGSY 1141

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE  V+EC       G   C D  GG+ C C
Sbjct: 1142 CEDLVDECSPSPCQNG-ATCTDYLGGYSCKC 1171



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C CT  YTG +CEVD  D C    C +G+ C +DG   ++C C PGY G +CE  ++ 
Sbjct: 550 YTCVCTEGYTGTHCEVDI-DECDPDPCHYGS-C-KDGVATFTCLCRPGYTGHHCETNIN- 605

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCR+ G+C
Sbjct: 606 --ECSSQPCRHGGTC 618



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 37/86 (43%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           YEC C   YTG+ C ++  D CA   C +G  C EDG   ++C CP GYH   C  EV  
Sbjct: 662 YECACEPGYTGSMCNINI-DECAGNPCHNGGTC-EDGINGFTCRCPEGYHDPTCLSEVNE 719

Query: 177 -SLDPLCVAGPCRN--NG-SCSVPPG 242
            + +P CV G CR+  NG  C   PG
Sbjct: 720 CNSNP-CVHGACRDSLNGYKCDCDPG 744



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            Y C C A Y G NC  +  D C S  C++G  C+ D    Y C CP G  G +CE+ V  
Sbjct: 1167 YSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDD 1224

Query: 180  ----LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                +DP+  +  C NNG+C    GG + + P
Sbjct: 1225 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1256



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 31/85 (36%), Positives = 47/85 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   Y G +CEV+  D CAS+ C H  RC+ D   ++ C+CP G+ G  C+ +V  
Sbjct: 474 FQCICMPGYEGVHCEVNT-DECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD- 530

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C + PC+N   C    G +TY+
Sbjct: 531 --ECASTPCKNGAKCL--DGPNTYT 551



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 30/75 (40%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C+ D  + C S  C HG  C +DG G Y C CP GY G  C+   +L
Sbjct: 1005 FTCLCPPGFTGSYCQHDVNE-CDSQPCLHGGTC-QDGCGSYRCTCPQGYTGPNCQ---NL 1059

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC+N G C
Sbjct: 1060 VHWCDSSPCKNGGKC 1074



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 32/81 (39%), Positives = 43/81 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   +TG NCE +  D C    C++G  CV DG   Y+C CPP + G YC  +V  
Sbjct: 241 HECACLPGFTGQNCEENIDD-CPGNNCKNGGACV-DGVNTYNCRCPPEWTGQYCTEDVDE 298

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L +   C+N G+C    GG
Sbjct: 299 CQL-MPNACQNGGTCHNTHGG 318



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 29/75 (38%), Positives = 46/75 (61%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A ++G +CE +  D C  ++C +G  CV DG   ++C CPPG+ G+YC+ +V+ 
Sbjct: 967  YTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCV-DGINSFTCLCPPGFTGSYCQHDVN- 1023

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC + G+C
Sbjct: 1024 --ECDSQPCLHGGTC 1036



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 42/87 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C    TG NCE++  D CAS+ C  G  C++   G Y C C PGY G+ C + +  
Sbjct: 625 YLCFCLKGTTGPNCEINL-DDCASSPCDSGT-CLDKIDG-YECACEPGYTGSMCNINID- 680

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C   PC N G+C     G T   P
Sbjct: 681 --ECAGNPCHNGGTCEDGINGFTCRCP 705



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/79 (37%), Positives = 39/79 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG +C  +  D CASAAC HGA C  D    + C+CP G  G  C     L
Sbjct: 319 YNCVCVNGWTGEDCSENIDD-CASAACFHGATC-HDRVASFYCECPHGRTGLLCH----L 372

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           +  C++ PC    +C   P
Sbjct: 373 NDACISNPCNEGSNCDTNP 391



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
 Frame = +2

Query: 227 QRAPRRRHLLCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           Q  P     +C CPP + G  C  DV+EC      C +GG C + V +Y C C AT +TG
Sbjct: 154 QCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRAT-HTG 212

Query: 404 ARCETNVNECEEDRALCGHGVCYDTYG-GFVCACQPATPG 520
             CE     C       G G C  T      CAC P   G
Sbjct: 213 PNCERPYVPCSPSPCQNG-GTCRPTGDVTHECACLPGFTG 251



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G +C+    DPCAS  C +G +C+      Y C CPP +HG  C  +V+ 
Sbjct: 125 YKCRCPPGWSGKSCQ--QADPCASNPCANGGQCLPF-EASYICHCPPSFHGPTCRQDVN- 180

Query: 183 DPLCVAGPCRNNGSC 227
           +     G CR+ G+C
Sbjct: 181 ECGQKPGLCRHGGTC 195



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C C   +TG NCE     CS  + C NGG C    +  + C C   G+TG  CE N+++C
Sbjct: 204 CVCRATHTGPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLP-GFTGQNCEENIDDC 261

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             +    G G C D    + C C P   G   T
Sbjct: 262 PGNNCKNG-GACVDGVNTYNCRCPPEWTGQYCT 293



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G NC+ +  + CAS  C +   C++D  G Y C+C   Y G  CE  V L
Sbjct: 775  YVCTCREGFSGPNCQTNINE-CASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCE--VVL 830

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYS 257
             P C   PCRN G C      +++S
Sbjct: 831  AP-CAPSPCRNGGECRQSEDYESFS 854



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE D  + CAS  CR+GA C  D    Y+C CP G+ G +CE   +  P
Sbjct: 931  CDCLPGFRGTFCEEDINE-CASDPCRNGANCT-DCVDSYTCTCPAGFSGIHCE---NNTP 985

Query: 189  LCVAGPCRNNGSC 227
             C    C N G+C
Sbjct: 986  DCTESSCFNGGTC 998



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C + YTG  C  D  D C+  A  C H  +C+    G + C C  GY G  CE++V+ 
Sbjct: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVN- 454

Query: 183 DPLCVAGPCRNNGSC 227
              CV+ PC+N+ +C
Sbjct: 455 --ECVSNPCQNDATC 467



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/75 (34%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G  C     + C +  CR+G  C      +Y C CPPG+ G  C+     
Sbjct: 85  YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QA 141

Query: 183 DPLCVAGPCRNNGSC 227
           DP C + PC N G C
Sbjct: 142 DP-CASNPCANGGQC 155



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRG--DYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+    +PC S  C++   C V D RG  DY+C C  G+ G  C     
Sbjct: 46  CVCGGAFVGPRCQDP--NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCL--TP 101

Query: 180 LDPLCVAGPCRNNGSCSV 233
           LD  C+  PCRN G+C +
Sbjct: 102 LDNACLTNPCRNGGTCDL 119



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 31/85 (36%), Positives = 43/85 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A +TG NCE     PC+ + C++G  C   G   + C C PG+ G  CE  +  
Sbjct: 202 YRCVCRATHTGPNCERPYV-PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID- 259

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
           D  C    C+N G+C    G +TY+
Sbjct: 260 D--CPGNNCKNGGAC--VDGVNTYN 280



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG +C  ++D+C+ +AAC +G  C D V ++ C+C   G TG  C  N + C 
Sbjct: 321 CVCVNGWTGEDCSENIDDCA-SAACFHGATCHDRVASFYCEC-PHGRTGLLCHLN-DACI 377

Query: 437 EDRALCGHGVCYDT---YGGFVCACQPATPG 520
            +   C  G   DT    G  +C C     G
Sbjct: 378 SNP--CNEGSNCDTNPVNGKAICTCPSGYTG 406



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP G+ G  CE D   C G+  CLNGG C+    + TC C    +TG  C+   
Sbjct: 1330 RGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGP-FTGPECQFPA 1387

Query: 425  NE-CEEDRALCGHGVCYDT 478
            +  C         G C  T
Sbjct: 1388 SSPCLGGNPCYNQGTCEPT 1406



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTGARCETNVNEC 433
           C CP G TG  C  + D C  +  C  G  C     N    CT  +GYTG  C  +V+EC
Sbjct: 359 CECPHGRTGLLCHLN-DACI-SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
                 C H G C +T G F C C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQC 440



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y    C  +  + C S  C HGA C  D    Y CDC PG+ GT C++    
Sbjct: 700 FTCRCPEGYHDPTCLSEVNE-CNSNPCVHGA-C-RDSLNGYKCDCDPGWSGTNCDIN--- 753

Query: 183 DPLCVAGPCRNNGSC 227
           +  C + PC N G+C
Sbjct: 754 NNECESNPCVNGGTC 768



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            Y C C + +TG  C+V +   C  AA          C+HG  CV+ G   + C C  GY 
Sbjct: 1081 YRCECPSGWTGLYCDVPSVS-CEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYT 1138

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+YCE    L   C   PC+N  +C+   GG
Sbjct: 1139 GSYCE---DLVDECSPSPCQNGATCTDYLGG 1166



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            Y C C   YTG NC+ +    C S+ C++G +C +     Y C+CP G+ G YC++  VS
Sbjct: 1043 YRCTCPQGYTGPNCQ-NLVHWCDSSPCKNGGKCWQT-HTQYRCECPSGWTGLYCDVPSVS 1100

Query: 180  LDPLC------VAGPCRNNGSC 227
             +         VA  C++ G C
Sbjct: 1101 CEVAAQRQGVDVARLCQHGGLC 1122



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAAC--RHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  CE D  + C S  C  R    CV+    D+ C+C  G+ G  CE   
Sbjct: 1251 YSCTCPPGFVGERCEGDVNE-CLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCE--- 1305

Query: 177  SLDPLCVAGPCRNNGSCSV 233
            S+   C   PC+N G+C+V
Sbjct: 1306 SVINGCKGKPCKNGGTCAV 1324



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C+C  G++G  C T +D       C NGG C +  +  Y C C   G++G  C+   + C
Sbjct: 87  CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC-PPGWSGKSCQ-QADPC 144

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C      ++C C P+  G T
Sbjct: 145 ASNPCANG-GQCLPFEASYICHCPPSFHGPT 174



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD------PCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTY 161
            Y+C C     G +CE++  D      P + S  C +   CV D  G YSC CPPG+ G  
Sbjct: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGER 1263

Query: 162  CELEVSLDPLCVAGPCRNNGS 224
            CE +V+    C++ PC   G+
Sbjct: 1264 CEGDVN---ECLSNPCDARGT 1281



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
            + C C A +TG  CE    + C    C++G  C       RG + C CP G+ G  CE +
Sbjct: 1291 FHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG-FICKCPAGFEGATCEND 1348

Query: 174  VSLDPLCVAGPCRNNGSCSVPPGGDT 251
                  C +  C N G+C   P   T
Sbjct: 1349 AR---TCGSLRCLNGGTCISGPRSPT 1371



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C  G+ C      G   C CP GY G  C  +V 
Sbjct: 357 FYCECPHGRTGLLCHLN--DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414

Query: 180 LDPLCVAGPCRNNGSC 227
              L  A PC + G C
Sbjct: 415 ECSL-GANPCEHAGKC 429



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC++G  C  +  G Y+C C  G+ G  C   +
Sbjct: 279 YNCRCPPEWTGQYCTEDV-DECQLMPNACQNGGTC-HNTHGGYNCVCVNGWTGEDCSENI 336

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C +  C +  +C
Sbjct: 337 D-D--CASAACFHGATC 350



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGD-YSCDCPPGYHGTYCEL 170
            C C   +TG  C+  A  PC     C +   C        Y C CP  ++G  C +
Sbjct: 1372 CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           CLNGG+C  A     C C    + G RC+ + N C
Sbjct: 31  CLNGGKCEAANGTEACVC-GGAFVGPRCQ-DPNPC 63


>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
          Length = 2556

 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 41/90 (45%), Positives = 51/90 (56%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP GYTG  C  DVDECS GA  C + G+C++ + ++ C C   GYTG RCE +VNE
Sbjct: 397 ICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC-LQGYTGPRCEIDVNE 455

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C  +        C D  G F C C P   G
Sbjct: 456 CVSNPCQ-NDATCLDQIGEFQCMCMPGYEG 484



 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 39/89 (43%), Positives = 50/89 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C +++DEC+G   C NGG C D +N +TC C   GY    C + VNEC 
Sbjct: 664 CACEPGYTGSMCNSNIDECAG-NPCHNGGTCEDGINGFTCRC-PEGYHDPTCLSEVNECN 721

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +   C HG C D+  G+ C C P   G+
Sbjct: 722 SNP--CVHGACRDSLNGYKCDCDPGWSGT 748



 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 38/83 (45%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG+NCE ++D+C G   C NGG CVD VN Y C C    +TG  C  +V+EC+
Sbjct: 243 CACLPGFTGQNCEENIDDCPG-NNCKNGGACVDGVNTYNCPCPPE-WTGQYCTEDVDECQ 300

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C + G C++T+GG+ C C
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVC 323



 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 39/89 (43%), Positives = 50/89 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG +CET+++ECS +  C   G C D  N Y C C   G TG  CE N+++C 
Sbjct: 589 CLCRPGYTGHHCETNINECS-SQPCRLRGTCQDPDNAYLCFC-LKGTTGPNCEINLDDCA 646

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
              + C  G C D   G+ CAC+P   GS
Sbjct: 647 S--SPCDSGTCLDKIDGYECACEPGYTGS 673



 Score = 85.4 bits (202), Expect = 2e-16
 Identities = 39/97 (40%), Positives = 56/97 (57%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCP G++G +CE +  +C+  ++C NGG CVD +N++TC C   G+TG+ C+  VNEC+
Sbjct: 970  CTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLC-PPGFTGSYCQHVVNECD 1027

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRV 547
                L G G C D  G   C C     G T   C+ +
Sbjct: 1028 SRPCLLG-GTCQDGRGLHRCTC---PQGYTGPNCQNL 1060



 Score = 85.0 bits (201), Expect = 2e-16
 Identities = 38/89 (42%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GY+GRNCETD+D+C     C NGG C D +N   CDC   G+ G  CE ++NEC 
Sbjct: 894  CHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDC-LPGFRGTFCEEDINECA 951

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
             D   C +G  C D    + C C     G
Sbjct: 952  SDP--CRNGANCTDCVDSYTCTCPAGFSG 978



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 39/95 (41%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G +CE + DEC+ ++ CL+ GRC+D +N + C+C  TG+TG  C+ +V+EC 
Sbjct: 476 CMCMPGYEGVHCEVNTDECA-SSPCLHNGRCLDKINEFQCEC-PTGFTGHLCQYDVDECA 533

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGSTATGC 538
                C +G  C D    + C C   T G T T C
Sbjct: 534 S--TPCKNGAKCLDGPNTYTCVC---TEGYTGTHC 563



 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 38/88 (43%), Positives = 45/88 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GYTG +CE D+DEC     C + G C D V  +TC C   GYTG  CETN+NEC 
Sbjct: 552 CVCTEGYTGTHCEVDIDECD-PDPC-HYGSCKDGVATFTCLC-RPGYTGHHCETNINECS 608

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    ++C C   T G
Sbjct: 609 SQPCRL-RGTCQDPDNAYLCFCLKGTTG 635



 Score = 80.6 bits (190), Expect = 4e-15
 Identities = 34/90 (37%), Positives = 49/90 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G NC+ + +EC  +  C+NGG C D  +   C C   G++G  C+TN+NEC 
Sbjct: 739 CDCDPGWSGTNCDINNNECE-SNPCVNGGTCKDMTSGIVCTC-REGFSGPNCQTNINECA 796

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +  L   G C D   G+ C C     G+T
Sbjct: 797 SNPCL-NKGTCIDDVAGYKCNCLLPYTGAT 825



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGR-CVDAVNNYTCDCTATGYTGARCETNVNEC 433
            CTCPPG+ G  CE DV+EC        G + CV  VN++ C+C A G+TG RCE+ +N C
Sbjct: 1254 CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA-GHTGRRCESVINGC 1312

Query: 434  EEDRALCGH--GVCYDTYGGFVCACQPATPGST 526
            +      G    V  +T  GF+C C     G+T
Sbjct: 1313 KGKPCKNGGTCAVASNTARGFICKCPAGFEGAT 1345



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 33/76 (43%), Positives = 43/76 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC A Y+G NCE D  D C    C +G  C  DG     CDC PG+ GT+CE +++ 
Sbjct: 892  YRCHCQAGYSGRNCETDI-DDCRPNPCHNGGSCT-DGINTAFCDCLPGFRGTFCEEDIN- 948

Query: 183  DPLCVAGPCRNNGSCS 230
               C + PCRN  +C+
Sbjct: 949  --ECASDPCRNGANCT 962



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/88 (40%), Positives = 43/88 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  GYTG  CE  VDECS  + C NG  C D +  Y+C C A GY G  C   ++EC 
Sbjct: 1132 CRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGGYSCKCVA-GYHGVNCSEEIDECL 1189

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C D    + C+C   T G
Sbjct: 1190 SHPCQNG-GTCLDLPNTYKCSCPRGTQG 1216



 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 34/83 (40%), Positives = 48/83 (57%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G TG NCE ++D+C  A++  + G C+D ++ Y C C   GYTG+ C +N++EC
Sbjct: 626 LCFCLKGTTGPNCEINLDDC--ASSPCDSGTCLDKIDGYECAC-EPGYTGSMCNSNIDEC 682

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
             +    G G C D   GF C C
Sbjct: 683 AGNPCHNG-GTCEDGINGFTCRC 704



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 36/87 (41%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C A YTG+ CE D  D C+ + C++GA C  D  G YSC C  GYHG  C  E+  
Sbjct: 1130 HHCRCQAGYTGSYCE-DLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVNCSEEID- 1186

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C++ PC+N G+C   P     S P
Sbjct: 1187 --ECLSHPCQNGGTCLDLPNTYKCSCP 1211



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 32/75 (42%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   YTG  CE+D  + C S  C++ A C+ D  G++ C C PGY G +C  EV+ 
Sbjct: 436 FECQCLQGYTGPRCEIDVNE-CVSNPCQNDATCL-DQIGEFQCMCMPGYEGVHC--EVNT 491

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC +NG C
Sbjct: 492 DE-CASSPCLHNGRC 505



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 35/89 (39%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            ++CTC  G++G NC+T+++EC+ +  CLN G C+D V  Y C+C    YTGA CE  +  
Sbjct: 775  IVCTCREGFSGPNCQTNINECA-SNPCLNKGTCIDDVAGYKCNCLLP-YTGATCEVVLAP 832

Query: 431  CEEDRALCGHGVC--YDTYGGFVCACQPA 511
            C       G G C   + Y  F C C  A
Sbjct: 833  CAPSPCRNG-GECRQSEDYESFSCVCPTA 860



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 39/107 (36%), Positives = 50/107 (46%), Gaps = 12/107 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDEC-------SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C+CP G  G +CE +VD+C       S +  C N G CVD V  Y+C C   G+ G RCE
Sbjct: 1208 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC-PPGFVGERCE 1266

Query: 416  TNVNECEEDRA-LCGHGVCYDTYGGFVCACQPATPG----STATGCR 541
             +VNEC  +     G   C      F C C+    G    S   GC+
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 1313



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/75 (41%), Positives = 46/75 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   +TG+ C+ D  D CAS  C++GA+C+ DG   Y+C C  GY GT+CE+++  
Sbjct: 512 FQCECPTGFTGHLCQYDV-DECASTPCKNGAKCL-DGPNTYTCVCTEGYTGTHCEVDID- 568

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC + GSC
Sbjct: 569 --ECDPDPC-HYGSC 580



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 33/88 (37%), Positives = 44/88 (50%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+TG  C+  V+EC  +  CL GG C D    + C C   GYTG  C+  V+ C+
Sbjct: 1008 CLCPPGFTGSYCQHVVNECD-SRPCLLGGTCQDGRGLHRCTC-PQGYTGPNCQNLVHWCD 1065

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C+ T+  + C C     G
Sbjct: 1066 SSPCKNG-GKCWQTHTQYRCECPSGWTG 1092



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 37/91 (40%), Positives = 44/91 (48%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAA---------CLNGGRCVDAVNNYTCDCTATGYTGAR 409
            C CP G+TG  C+     C  AA          C +GG CVDA N + C C A GYTG+ 
Sbjct: 1084 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQA-GYTGSY 1142

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE  V+EC       G   C D  GG+ C C
Sbjct: 1143 CEDLVDECSPSPCQNG-ATCTDYLGGYSCKC 1172



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 31/85 (36%), Positives = 47/85 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   Y G +CEV+  D CAS+ C H  RC+ D   ++ C+CP G+ G  C+ +V  
Sbjct: 474 FQCMCMPGYEGVHCEVNT-DECASSPCLHNGRCL-DKINEFQCECPTGFTGHLCQYDVD- 530

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C + PC+N   C    G +TY+
Sbjct: 531 --ECASTPCKNGAKCL--DGPNTYT 551



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/78 (42%), Positives = 44/78 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C CT  YTG +CEVD  D C    C +G+ C +DG   ++C C PGY G +CE  ++ 
Sbjct: 550 YTCVCTEGYTGTHCEVDI-DECDPDPCHYGS-C-KDGVATFTCLCRPGYTGHHCETNIN- 605

Query: 183 DPLCVAGPCRNNGSCSVP 236
              C + PCR  G+C  P
Sbjct: 606 --ECSSQPCRLRGTCQDP 621



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
            Y C C A Y G NC  +  D C S  C++G  C+ D    Y C CP G  G +CE+ V  
Sbjct: 1168 YSCKCVAGYHGVNCSEEI-DECLSHPCQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDD 1225

Query: 180  ----LDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
                +DP+  +  C NNG+C    GG + + P
Sbjct: 1226 CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP 1257



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 32/81 (39%), Positives = 43/81 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C   +TG NCE +  D C    C++G  CV DG   Y+C CPP + G YC  +V  
Sbjct: 241 HECACLPGFTGQNCEENIDD-CPGNNCKNGGACV-DGVNTYNCPCPPEWTGQYCTEDVDE 298

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
             L +   C+N G+C    GG
Sbjct: 299 CQL-MPNACQNGGTCHNTHGG 318



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
 Frame = +3

Query: 3    YECHC-TARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C TA   G  CEVD  + C  + CRHGA C ++  G Y C C  GY G  CE ++ 
Sbjct: 853  FSCVCPTAGAKGQTCEVDINE-CVLSPCRHGASC-QNTHGXYRCHCQAGYSGRNCETDID 910

Query: 180  LDPLCVAGPCRNNGSCS 230
             D  C   PC N GSC+
Sbjct: 911  -D--CRPNPCHNGGSCT 924



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           YEC C   YTG+ C  +  D CA   C +G  C EDG   ++C CP GYH   C  EV  
Sbjct: 662 YECACEPGYTGSMCNSNI-DECAGNPCHNGGTC-EDGINGFTCRCPEGYHDPTCLSEVNE 719

Query: 177 -SLDPLCVAGPCRN--NG-SCSVPPG 242
            + +P CV G CR+  NG  C   PG
Sbjct: 720 CNSNP-CVHGACRDSLNGYKCDCDPG 744



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 30/79 (37%), Positives = 39/79 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG +C  +  D CASAAC HGA C  D    + C+CP G  G  C     L
Sbjct: 319 YNCVCVNGWTGEDCSENIDD-CASAACFHGATC-HDRVASFYCECPHGRTGLLCH----L 372

Query: 183 DPLCVAGPCRNNGSCSVPP 239
           +  C++ PC    +C   P
Sbjct: 373 NDACISNPCNEGSNCDTNP 391



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN--NYTCDCTATGYTGARCETNVNE 430
            C C   YTG  CE  +  C+  + C NGG C  + +  +++C C   G  G  CE ++NE
Sbjct: 815  CNCLLPYTGATCEVVLAPCA-PSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDINE 873

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C    + C HG  C +T+G + C CQ    G
Sbjct: 874  CV--LSPCRHGASCQNTHGXYRCHCQAGYSG 902



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/77 (40%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-DGRGDYSCDCP-PGYHGTYCELEV 176
            Y+C+C   YTG  CEV    PCA + CR+G  C + +    +SC CP  G  G  CE+++
Sbjct: 813  YKCNCLLPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI 871

Query: 177  SLDPLCVAGPCRNNGSC 227
            +    CV  PCR+  SC
Sbjct: 872  N---ECVLSPCRHGASC 885



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C    TG NCE++  D CAS+ C  G  C++   G Y C C PGY G+ C   +  
Sbjct: 625 YLCFCLKGTTGPNCEINL-DDCASSPCDSGT-CLDKIDG-YECACEPGYTGSMCNSNID- 680

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C   PC N G+C     G T   P
Sbjct: 681 --ECAGNPCHNGGTCEDGINGFTCRCP 705



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/75 (38%), Positives = 44/75 (58%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C A ++G +CE +  D C  ++C +G  CV DG   ++C CPPG+ G+YC+  V+ 
Sbjct: 968  YTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCV-DGINSFTCLCPPGFTGSYCQHVVN- 1024

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC   G+C
Sbjct: 1025 --ECDSRPCLLGGTC 1037



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
 Frame = +2

Query: 227 QRAPRRRHLLCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           Q  P     +C CPP + G  C  DV+EC      C +GG C + V +Y C C AT +TG
Sbjct: 154 QCLPFEASYICHCPPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRAT-HTG 212

Query: 404 ARCETNVNECEEDRALCGHGVCYDTYG-GFVCACQPATPG 520
             CE     C       G G C  T      CAC P   G
Sbjct: 213 PNCERPYVPCSPSPCQNG-GTCRPTGDVTHECACLPGFTG 251



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A +TG NCE     PC+ + C++G  C   G   + C C PG+ G  CE  +  
Sbjct: 202 YRCVCRATHTGPNCERPYV-PCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENID- 259

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D  C    C+N G+C    G +TY+ P
Sbjct: 260 D--CPGNNCKNGGAC--VDGVNTYNCP 282



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           C C   +TG NCE     CS  + C NGG C    +  + C C   G+TG  CE N+++C
Sbjct: 204 CVCRATHTGPNCERPYVPCS-PSPCQNGGTCRPTGDVTHECACLP-GFTGQNCEENIDDC 261

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             +    G G C D    + C C P   G   T
Sbjct: 262 PGNNCKNG-GACVDGVNTYNCPCPPEWTGQYCT 293



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G  CE D  + CAS  CR+GA C  D    Y+C CP G+ G +CE   +  P
Sbjct: 932  CDCLPGFRGTFCEEDINE-CASDPCRNGANCT-DCVDSYTCTCPAGFSGIHCE---NNTP 986

Query: 189  LCVAGPCRNNGSC 227
             C    C N G+C
Sbjct: 987  DCTESSCFNGGTC 999



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G +C+    DPCAS  C +G +C+      Y C CPP +HG  C  +V+ 
Sbjct: 125 YKCRCPPGWSGKSCQ--QADPCASNPCANGGQCLPF-EASYICHCPPSFHGPTCRQDVN- 180

Query: 183 DPLCVAGP--CRNNGSC 227
              C   P  CR+ G+C
Sbjct: 181 --ECGQKPRLCRHGGTC 195



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           C C + YTG  C  D  D C+  A  C H  +C+    G + C C  GY G  CE++V+ 
Sbjct: 398 CTCPSGYTGPACSQDV-DECSLGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVN- 454

Query: 183 DPLCVAGPCRNNGSC 227
              CV+ PC+N+ +C
Sbjct: 455 --ECVSNPCQNDATC 467



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/75 (34%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G  C     + C +  CR+G  C      +Y C CPPG+ G  C+     
Sbjct: 85  YACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QA 141

Query: 183 DPLCVAGPCRNNGSC 227
           DP C + PC N G C
Sbjct: 142 DP-CASNPCANGGQC 155



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 29/78 (37%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRG--DYSCDCPPGYHGTYCELEVS 179
           C C   + G  C+    +PC S  C++   C V D RG  DY+C C  G+ G  C     
Sbjct: 46  CVCGGAFVGPRCQDP--NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCL--TP 101

Query: 180 LDPLCVAGPCRNNGSCSV 233
           LD  C+  PCRN G+C +
Sbjct: 102 LDNACLTNPCRNGGTCDL 119



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/83 (36%), Positives = 42/83 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   ++G NC+ +  + CAS  C +   C++D  G Y C+C   Y G  CE  V L P
Sbjct: 777  CTCREGFSGPNCQTNINE-CASNPCLNKGTCIDDVAG-YKCNCLLPYTGATCE--VVLAP 832

Query: 189  LCVAGPCRNNGSCSVPPGGDTYS 257
             C   PCRN G C      +++S
Sbjct: 833  -CAPSPCRNGGECRQSEDYESFS 854



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   +TG+ C+    + C S  C  G  C +DGRG + C CP GY G  C+   +L
Sbjct: 1006 FTCLCPPGFTGSYCQHVVNE-CDSRPCLLGGTC-QDGRGLHRCTCPQGYTGPNCQ---NL 1060

Query: 183  DPLCVAGPCRNNGSC 227
               C + PC+N G C
Sbjct: 1061 VHWCDSSPCKNGGKC 1075



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG +C  ++D+C+ +AAC +G  C D V ++ C+C   G TG  C  N + C 
Sbjct: 321 CVCVNGWTGEDCSENIDDCA-SAACFHGATCHDRVASFYCEC-PHGRTGLLCHLN-DACI 377

Query: 437 EDRALCGHGVCYDT---YGGFVCACQPATPG 520
            +   C  G   DT    G  +C C     G
Sbjct: 378 SNP--CNEGSNCDTNPVNGKAICTCPSGYTG 406



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
 Frame = +2

Query: 245  RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            R  +C CP G+ G  CE D   C G+  CLNGG C+    + TC C    +TG  C+   
Sbjct: 1331 RGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGP-FTGPECQFPA 1388

Query: 425  NE-CEEDRALCGHGVCYDT 478
            +  C         G C  T
Sbjct: 1389 SSPCLGGNPCYNQGTCEPT 1407



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTGARCETNVNEC 433
           C CP G TG  C  + D C  +  C  G  C     N    CT  +GYTG  C  +V+EC
Sbjct: 359 CECPHGRTGLLCHLN-DACI-SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDEC 416

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
                 C H G C +T G F C C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQC 440



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y    C  +  + C S  C HGA C  D    Y CDC PG+ GT C++    
Sbjct: 700 FTCRCPEGYHDPTCLSEVNE-CNSNPCVHGA-C-RDSLNGYKCDCDPGWSGTNCDIN--- 753

Query: 183 DPLCVAGPCRNNGSC 227
           +  C + PC N G+C
Sbjct: 754 NNECESNPCVNGGTC 768



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            Y C C + +TG  C+V +   C  AA          C+HG  CV+ G   + C C  GY 
Sbjct: 1082 YRCECPSGWTGLYCDVPSVS-CEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYT 1139

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+YCE    L   C   PC+N  +C+   GG
Sbjct: 1140 GSYCE---DLVDECSPSPCQNGATCTDYLGG 1167



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAAC--RHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  CE D  + C S  C  R    CV+    D+ C+C  G+ G  CE   
Sbjct: 1252 YSCTCPPGFVGERCEGDVNE-CLSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCE--- 1306

Query: 177  SLDPLCVAGPCRNNGSCSV 233
            S+   C   PC+N G+C+V
Sbjct: 1307 SVINGCKGKPCKNGGTCAV 1325



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C+C  G++G  C T +D       C NGG C +  +  Y C C   G++G  C+   + C
Sbjct: 87  CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC-PPGWSGKSCQ-QADPC 144

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C      ++C C P+  G T
Sbjct: 145 ASNPCANG-GQCLPFEASYICHCPPSFHGPT 174



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
            + C C   YTG NC+ +    C S+ C++G +C +     Y C+CP G+ G YC++  VS
Sbjct: 1044 HRCTCPQGYTGPNCQ-NLVHWCDSSPCKNGGKCWQT-HTQYRCECPSGWTGLYCDVPSVS 1101

Query: 180  LDPLC------VAGPCRNNGSC 227
             +         VA  C++ G C
Sbjct: 1102 CEVAAQRQGVDVARLCQHGGLC 1123



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD------PCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTY 161
            Y+C C     G +CE++  D      P + S  C +   CV D  G YSC CPPG+ G  
Sbjct: 1206 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGER 1264

Query: 162  CELEVSLDPLCVAGPCRNNGS 224
            CE +V+    C++ PC   G+
Sbjct: 1265 CEGDVN---ECLSNPCDARGT 1282



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
            + C C A +TG  CE    + C    C++G  C       RG + C CP G+ G  CE +
Sbjct: 1292 FHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG-FICKCPAGFEGATCEND 1349

Query: 174  VSLDPLCVAGPCRNNGSCSVPPGGDT 251
                  C +  C N G+C   P   T
Sbjct: 1350 AR---TCGSLRCLNGGTCISGPRSPT 1372



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C  G+ C      G   C CP GY G  C  +V 
Sbjct: 357 FYCECPHGRTGLLCHLN--DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD 414

Query: 180 LDPLCVAGPCRNNGSC 227
              L  A PC + G C
Sbjct: 415 ECSL-GANPCEHAGKC 429



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   +TG  C  D  D C     AC++G  C  +  G Y+C C  G+ G  C   +
Sbjct: 279 YNCPCPPEWTGQYCTEDV-DECQLMPNACQNGGTC-HNTHGGYNCVCVNGWTGEDCSENI 336

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C +  C +  +C
Sbjct: 337 D-D--CASAACFHGATC 350



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGD-YSCDCPPGYHGTYCEL 170
            C C   +TG  C+  A  PC     C +   C        Y C CP  ++G  C +
Sbjct: 1373 CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1428



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           CLNGG+C  A     C C    + G RC+ + N C
Sbjct: 31  CLNGGKCEAANGTEACVC-GGAFVGPRCQ-DPNPC 63


>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
           protein.
          Length = 1406

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1336



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
           protein.
          Length = 1376

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/59 (45%), Positives = 37/59 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE +V+
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDVS 1337



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 22/58 (37%), Positives = 30/58 (51%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            +C C   +TG  CE D  D CAS  C +G  C +D    + C C   + G  CE++VS
Sbjct: 1282 KCMCRPGFTGEWCEKDI-DECASDPCVNGGLC-QDLLNKFQCLCDVAFAGERCEVDVS 1337



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1336



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1336



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1406

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1336



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
          Length = 1376

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 248 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 305

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 334



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 229

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 230 SQPCLNG-ATCQDALGAYFCDCAPGFLG 256



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 246 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 300

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 301 LMPLCWSKPCHNNATC 316



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1163 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1219

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1220 SHQ--CANGATCISHTNGYSCLC 1240



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 208 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 264

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 265 --ECASQPCLHGGLC 277



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 382 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 441 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 226

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 227 --ECWSQPCLNGATC 239



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1257

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1291



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/59 (45%), Positives = 37/59 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE +V+
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDVS 1337



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 284 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 341

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 342 ---ECNSNPCQSNGEC 354



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 286 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 343

Query: 434 EED 442
             +
Sbjct: 344 NSN 346



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE------DGR-------------GDY 125
           Y CHC   YTG  CE+D  + C S  C+    CVE       GR               Y
Sbjct: 323 YTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGY 381

Query: 126 SCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 382 VCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 424



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1148 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1204

Query: 509  ATPG 520
               G
Sbjct: 1205 GYTG 1208



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/102 (33%), Positives = 46/102 (45%), Gaps = 20/102 (19%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNNYTC 376
           C C PGYTG  CE D++EC+ +  C + G CV+                      + Y C
Sbjct: 325 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383

Query: 377 DCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 384 IC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 423



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1198 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1253

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1254 LPSTVCGNEKTNLTC 1268



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1161 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1216

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1217 --NCQSHQCANGATC 1229



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1296

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1297 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1329



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 381 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 438

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 439 S-DILLG--CTHQQCLNNGTC 456



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1143 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1192



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1294

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1295 EKDID---ECASDPCVNGGLC 1312



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 22/58 (37%), Positives = 30/58 (51%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            +C C   +TG  CE D  D CAS  C +G  C +D    + C C   + G  CE++VS
Sbjct: 1282 KCMCRPGFTGEWCEKDI-DECASDPCVNGGLC-QDLLNKFQCLCDVAFAGERCEVDVS 1337



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 419 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 477

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 478 SLCEIATTL 486



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54   AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 886  AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 939



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
            C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 896  CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 951

Query: 506  PATPGST 526
                G +
Sbjct: 952  AVFNGQS 958



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707


>AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isoform
           II precursor variant protein.
          Length = 441

 Score = 86.2 bits (204), Expect = 9e-17
 Identities = 35/89 (39%), Positives = 51/89 (57%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE + DEC+ +  CL+GG CVD  N Y+C+CT +G+TG  CET +  C 
Sbjct: 273 CDCAPGFLGDHCELNTDECA-SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC- 330

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
             +    +  C D+   + C C P   G+
Sbjct: 331 WSKPCHNNATCEDSVDNYTCHCWPGYTGA 359



 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    Y+G  CE  ++EC 
Sbjct: 197 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCIC-PHNYSGVNCELEIDECW 254

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G   C D  G + C C P   G
Sbjct: 255 SQPCLNG-ATCQDALGAYFCDCAPGFLG 281



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 159 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 213

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 214 ECASDPCKNEATC 226



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP-PGYHGTYCELEVS 179
           Y C C   + G++CE++  D CAS  C HG  CV DG   YSC+C   G+ GT+CE   +
Sbjct: 271 YFCDCAPGFLGDHCELNT-DECASQPCLHGGLCV-DGENRYSCNCTGSGFTGTHCE---T 325

Query: 180 LDPLCVAGPCRNNGSC 227
           L PLC + PC NN +C
Sbjct: 326 LMPLCWSKPCHNNATC 341



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 114 PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 171

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 172 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 205



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/75 (42%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G NCE++  D C S  C +GA C +D  G Y CDC PG+ G +CEL    
Sbjct: 233 YTCICPHNYSGVNCELEI-DECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTD- 289

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 290 --ECASQPCLHGGLC 302



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G  CELE+  
Sbjct: 195 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGVNCELEID- 251

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N  +C
Sbjct: 252 --ECWSQPCLNGATC 264



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTAR-YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y C+CT   +TG +CE      C S  C + A C ED   +Y+C C PGY G  CE++++
Sbjct: 309 YSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATC-EDSVDNYTCHCWPGYTGAQCEIDLN 366

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC++NG C
Sbjct: 367 ---ECNSNPCQSNGEC 379



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/63 (46%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
 Frame = +2

Query: 257 CTCP-PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C   G+TG +CET +  C  +  C N   C D+V+NYTC C   GYTGA+CE ++NEC
Sbjct: 311 CNCTGSGFTGTHCETLMPLC-WSKPCHNNATCEDSVDNYTCHCWP-GYTGAQCEIDLNEC 368

Query: 434 EED 442
             +
Sbjct: 369 NSN 371



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 121 CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 175

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 176 ECASSPCQNGAVCQ--DGIDGYS 196



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 79  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 137

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 138 --SCGKNSCQHGGICHQDP 154



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD 355
           C C PGYTG  CE D++EC+ +  C + G CV+
Sbjct: 350 CHCWPGYTGAQCEIDLNECN-SNPCQSNGECVE 381



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 59  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 115



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 63  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 121

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 122 KCPPGYSGT 130


>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
           protein.
          Length = 1214

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 602 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 659

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 660 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 688



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 460 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 517

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 518 PNP--CQNGAQCYNRASDYFCKC 538



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 309 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 366

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 367 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 395



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 640 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 697

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 698 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 731



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 755  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 812

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 813  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 840



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 423 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 479

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 480 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 507



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 347 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 404

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 405 AKPCVNAKS-CKNLIASYYCDCLPGWMG 431



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 269 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 327

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 328 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 359



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 600 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 656

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 657 D--CSQNPCHNGGTC 669



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 458 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 514

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 515 --YCEPNPCQNGAQC 527



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 421 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 476

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 477 --ECASNPCLNGGHC 489



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 267 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 323

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 324 EHACLSDPCHNRGSC 338



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 791  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 847

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 848  RPCITMGSVIPDGA 861



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 345 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 401

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 402 --ECEAKPCVNAKSC 414



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 676 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 731

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 732 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 759



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 793 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 843



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 716 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 773

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 774 SPHPCYNSGTCVDGDNWYRCECAPGFAG 801



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 496 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 550

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 551 KDHCRTTPCEVIDSCTV 567



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 383 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 439

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 440 DCL---GQCQNDASC 451



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 714 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 771

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 772 D--CSPHPCYNSGTC 784



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 678 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 735

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 736 LPNPCHNGGTCVVNGESFTCVCKEGWEG 763



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 582 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 631



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 753 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 809

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 810 --ECQSSPCAFGATC 822



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 213 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 269



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 466 YAGDHCERDIDECASNPCLNGGH 488


>U77493-1|AAB19224.1|  263|Homo sapiens Notch2 protein.
          Length = 263

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 37/88 (42%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GYTG  CE  +DEC+ +  C +G  C D +  Y C+C   GY G  CE  V+EC+
Sbjct: 169 CQCPVGYTGSYCEEQLDECA-SNPCQHGATCSDFIGGYRCEC-VPGYQGVNCEYEVDECQ 226

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C+C P T G
Sbjct: 227 NQPCQNG-GTCIDLVNHFKCSCPPGTRG 253



 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 32/82 (39%), Positives = 49/82 (59%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE +++EC+  ++C NGG CVD +N+++C C   G+TG+ C   +NEC 
Sbjct: 7   CKCQAGFDGVHCENNINECT-ESSCFNGGTCVDGINSFSCLC-PVGFTGSFCLHEINECS 64

Query: 437 EDRALCGHGVCYDTYGGFVCAC 502
               L   G C D  G + C+C
Sbjct: 65  SHPCL-NDGTCVDGLGTYRCSC 85



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/73 (47%), Positives = 40/73 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG+ CE    D CAS  C+HGA C  D  G Y C+C PGY G  CE EV    
Sbjct: 169 CQCPVGYTGSYCEEQL-DECASNPCQHGATC-SDFIGGYRCECVPGYQGVNCEYEVD--- 223

Query: 189 LCVAGPCRNNGSC 227
            C   PC+N G+C
Sbjct: 224 ECQNQPCQNGGTC 236



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 29/59 (49%), Positives = 36/59 (61%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C C PGY G NCE +VDEC     C NGG C+D VN++ C C   G  G  CE N+++C
Sbjct: 207 CECVPGYQGVNCEYEVDECQN-QPCQNGGTCIDLVNHFKCSC-PPGTRGLLCEENIDDC 263



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 28/75 (37%), Positives = 44/75 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A + G +CE +  + C  ++C +G  CV DG   +SC CP G+ G++C  E++ 
Sbjct: 5   YTCKCQAGFDGVHCENNINE-CTESSCFNGGTCV-DGINSFSCLCPVGFTGSFCLHEIN- 61

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+G+C
Sbjct: 62  --ECSSHPCLNDGTC 74



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 29/75 (38%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG+ C  +  + C+S  C +   CV DG G Y C CP GY G  C+  V+ 
Sbjct: 43  FSCLCPVGFTGSFCLHEINE-CSSHPCLNDGTCV-DGLGTYRCSCPLGYTGKNCQTLVN- 99

Query: 183 DPLCVAGPCRNNGSC 227
             LC   PC+N G+C
Sbjct: 100 --LCSRSPCKNKGTC 112



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GYTG+NC+T V+ CS  + C N G CV    +  C C  +G+ GA C+     C+
Sbjct: 83  CSCPLGYTGKNCQTLVNLCS-RSPCKNKGTCVQKKASPQCLC-PSGWVGAYCDVPNVSCD 140

Query: 437 EDRA--------LCGH-GVCYDTYGGFVCACQPATPGS 523
              +        LC H GVC +      C C     GS
Sbjct: 141 IAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGS 178



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 25/55 (45%), Positives = 28/55 (50%)
 Frame = +2

Query: 359 VNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           VN+YTC C A G+ G  CE N+NEC E     G G C D    F C C     GS
Sbjct: 2   VNSYTCKCQA-GFDGVHCENNINECTESSCFNG-GTCVDGINSFSCLCPVGFTGS 54



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 22/55 (40%), Positives = 28/55 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           Y C C   Y G NCE +  D C +  C++G  C+ D    + C CPPG  G  CE
Sbjct: 205 YRCECVPGYQGVNCEYEV-DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRGLLCE 257



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVD--AGDPCASAA-------CRHGARCVEDGRGDYSCDCPPGYHGT 158
           +C C + + G  C+V   + D  AS         C+H   C+  G   Y C CP GY G+
Sbjct: 120 QCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY-CQCPVGYTGS 178

Query: 159 YCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           YCE +  LD  C + PC++  +CS   GG
Sbjct: 179 YCEEQ--LDE-CASNPCQHGATCSDFIGG 204



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVS 179
           Y C C   YTG NC+    + C+ + C++   CV+  +    C CP G+ G YC++  VS
Sbjct: 81  YRCSCPLGYTGKNCQTLV-NLCSRSPCKNKGTCVQK-KASPQCLCPSGWVGAYCDVPNVS 138

Query: 180 LD 185
            D
Sbjct: 139 CD 140



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 11/22 (50%), Positives = 15/22 (68%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDEC 313
           H  C+CPPG  G  CE ++D+C
Sbjct: 242 HFKCSCPPGTRGLLCEENIDDC 263


>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
           1 protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIRDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
           syndrome) protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
           Jagged 1 protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 82.2 bits (194), Expect = 1e-15
 Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CLNGG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLNGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLNG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C +G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLNGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 28/75 (37%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N G C
Sbjct: 490 --ECASNPCLNGGHC 502



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 12/23 (52%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
 Frame = +1

Query: 511 YTGEHCHR-MSACASGPCGREGH 576
           Y G+HC R +  CAS PC   GH
Sbjct: 479 YAGDHCERDIDECASNPCLNGGH 501


>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
          Length = 1218

 Score = 84.2 bits (199), Expect = 3e-16
 Identities = 36/90 (40%), Positives = 51/90 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++++C  +  C NGG C+D VN+Y C C + G+ GA CETN+N+C 
Sbjct: 615 CDCNKGFTGTYCHENINDCE-SNPCRNGGTCIDGVNSYKCIC-SDGWEGAYCETNINDCS 672

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
           ++    G G C D    F C C+    G T
Sbjct: 673 QNPCHNG-GTCRDLVNDFYCDCKNGWKGKT 701



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 33/83 (39%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGY G +CE D+DEC+ +  CL+GG C + +N + C C  TG++G  C+ +++ CE
Sbjct: 473 CICPPGYAGDHCERDIDECA-SNPCLDGGHCQNEINRFQCLC-PTGFSGNLCQLDIDYCE 530

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
            +   C +G  CY+    + C C
Sbjct: 531 PNP--CQNGAQCYNRASDYFCKC 551



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP GY+G NCE     C  +  C N G C +    + C+C+  G+TG  C TN+++C 
Sbjct: 322 CSCPEGYSGPNCEIAEHACL-SDPCHNRGSCKETSLGFECECSP-GWTGPTCSTNIDDCS 379

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            +   C HG  C D   GF C C P   G T
Sbjct: 380 PNN--CSHGGTCQDLVNGFKCVCPPQWTGKT 408



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CET++++CS    C NGG C D VN++ CDC   G+ G  C +  ++C+
Sbjct: 653 CICSDGWEGAYCETNINDCS-QNPCHNGGTCRDLVNDFYCDCK-NGWKGKTCHSRDSQCD 710

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTATGCR 541
           E  A C +G  CYD    F C C     G+T    R
Sbjct: 711 E--ATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIAR 744



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 768  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 825

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                  G   C D   G+ C C P   G+
Sbjct: 826  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 853



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/89 (37%), Positives = 46/89 (51%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G+NC+ ++++C G   C N   C D VN Y C C   GY G  CE +++EC 
Sbjct: 436 CDCLPGWMGQNCDININDCLG--QCQNDASCRDLVNGYRCIC-PPGYAGDHCERDIDECA 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +  L G G C +    F C C     G+
Sbjct: 493 SNPCLDG-GHCQNEINRFQCLCPTGFSGN 520



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+TG  C T++D+CS    C +GG C D VN + C C    +TG  C+ + NECE
Sbjct: 360 CECSPGWTGPTCSTNIDDCS-PNNCSHGGTCQDLVNGFKCVCPPQ-WTGKTCQLDANECE 417

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               +     C +    + C C P   G
Sbjct: 418 AKPCVNAKS-CKNLIASYYCDCLPGWMG 444



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVD-AVNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G+ C+ D++ C     CLNGG C +   + Y C C   GY+G  CE   + C
Sbjct: 282 CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC-PEGYSGPNCEIAEHAC 340

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             D      G C +T  GF C C P   G T +
Sbjct: 341 LSD-PCHNRGSCKETSLGFECECSPGWTGPTCS 372



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 29/75 (38%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  C  +  D C S  CR+G  C+ DG   Y C C  G+ G YCE  ++ 
Sbjct: 613 FTCDCNKGFTGTYCHENIND-CESNPCRNGGTCI-DGVNSYKCICSDGWEGAYCETNIN- 669

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G+C
Sbjct: 670 D--CSQNPCHNGGTC 682



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G++CE D  D CAS  C  G  C ++    + C CP G+ G  C+L++  
Sbjct: 471 YRCICPPGYAGDHCERDI-DECASNPCLDGGHC-QNEINRFQCLCPTGFSGNLCQLDID- 527

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC+N   C
Sbjct: 528 --YCEPNPCQNGAQC 540



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D         C +G  C   G   Y C CP GY G  CE+    
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI---A 336

Query: 183 DPLCVAGPCRNNGSC 227
           +  C++ PC N GSC
Sbjct: 337 EHACLSDPCHNRGSC 351



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G NC+++  D C    C++ A C +   G Y C CPPGY G +CE ++  
Sbjct: 434 YYCDCLPGWMGQNCDININD-CLGQ-CQNDASCRDLVNG-YRCICPPGYAGDHCERDID- 489

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC + G C
Sbjct: 490 --ECASNPCLDGGHC 502



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 804  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 860

Query: 183  DPLCVAGPCRNNGS 224
             P    G    +G+
Sbjct: 861  RPCITMGSVIPDGA 874



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C+  +TG  C  +  D C+   C HG  C +D    + C CPP + G  C+L+ + 
Sbjct: 358 FECECSPGWTGPTCSTNI-DDCSPNNCSHGGTC-QDLVNGFKCVCPPQWTGKTCQLDAN- 414

Query: 183 DPLCVAGPCRNNGSC 227
              C A PC N  SC
Sbjct: 415 --ECEAKPCVNAKSC 427



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 25/90 (27%), Positives = 43/90 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C  A C +G  C ++G   + C CP G+ GT C   ++ 
Sbjct: 689 FYCDCKNGWKGKTCH-SRDSQCDEATCNNGGTCYDEGDA-FKCMCPGGWEGTTCN--IAR 744

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPVRQ 272
           +  C+  PC N G+C V   G++++   ++
Sbjct: 745 NSSCLPNPCHNGGTCVV--NGESFTCVCKE 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 806 CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 856



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/88 (31%), Positives = 35/88 (39%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C    +       C NGG CV    ++TC C   G+ G  C  N N+C 
Sbjct: 729 CMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC- 786

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C D    + C C P   G
Sbjct: 787 SPHPCYNSGTCVDGDNWYRCECAPGFAG 814



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/77 (35%), Positives = 37/77 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++GN C++D  D C    C++GA+C      DY C CP  Y G  C     L
Sbjct: 509 FQCLCPTGFSGNLCQLDI-DYCEPNPCQNGAQCYNRA-SDYFCKCPEDYEGKNCS---HL 563

Query: 183 DPLCVAGPCRNNGSCSV 233
              C   PC    SC+V
Sbjct: 564 KDHCRTTPCEVIDSCTV 580



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/75 (33%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C  ++TG  C++DA + C +  C +   C ++    Y CDC PG+ G  C++ ++ 
Sbjct: 396 FKCVCPPQWTGKTCQLDANE-CEAKPCVNAKSC-KNLIASYYCDCLPGWMGQNCDININ- 452

Query: 183 DPLCVAGPCRNNGSC 227
           D L   G C+N+ SC
Sbjct: 453 DCL---GQCQNDASC 464



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C +     C    C +G  CV +G   ++C C  G+ G  C    + 
Sbjct: 727 FKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTN- 784

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N+G+C
Sbjct: 785 D--CSPHPCYNSGTC 797



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 25/88 (28%), Positives = 33/88 (37%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C   A C NGG C D  + + C C   G+ G  C    N   
Sbjct: 691 CDCKNGWKGKTCHSRDSQCD-EATCNNGGTCYDEGDAFKCMCPG-GWEGTTCNIARNSSC 748

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C      F C C+    G
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEG 776



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 20/53 (37%), Positives = 29/53 (54%)
 Frame = +3

Query: 69  ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           +S  C    +C     G ++CDC  G+ GTYC   ++ D  C + PCRN G+C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-D--CESNPCRNGGTC 644



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 766 FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 822

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 823 --ECQSSPCAFGATC 835



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 18/58 (31%), Positives = 22/58 (37%), Gaps = 1/58 (1%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           G  C  A CR G        +    C C  G+ G YC+  +   P CV G C     C
Sbjct: 226 GRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIP-HPGCVHGICNEPWQC 282


>AY358892-1|AAQ89251.1|  723|Homo sapiens DLL1 protein.
          Length = 723

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY+G NCE  +D CS ++ C NG +CVD  + Y C C A G++G  C+ NV++C 
Sbjct: 391 CRCPVGYSGFNCEKKIDYCS-SSPCSNGAKCVDLGDAYLCRCQA-GFSGRHCDDNVDDCA 448

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C C P   G
Sbjct: 449 SSPCANG-GTCRDGVNDFSCTCPPGYTG 475



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G++GR+C+ +VD+C+ ++ C NGG C D VN+++C C   GYTG  C   V+ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCA-SSPCANGGTCRDGVNDFSCTC-PPGYTGRNCSAPVSRC 485

Query: 434 EEDRALCGHG-VCYDTYGGFVCAC 502
           E   A C +G  C++    +VC C
Sbjct: 486 E--HAPCHNGATCHERGHRYVCEC 507



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  CE+   D C  + C++G  C  D    YSC CPPG++G  CEL    
Sbjct: 312 YTCSCRPGYTGATCELGI-DECDPSPCKNGGSCT-DLENSYSCTCPPGFYGKICELSAM- 368

Query: 183 DPLCVAGPCRNNGSCS-VPPGGDTYSAPV 266
              C  GPC N G CS  P GG +   PV
Sbjct: 369 --TCADGPCFNGGRCSDSPDGGYSCRCPV 395



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +C+ D  D CAS+ C +G  C  DG  D+SC CPPGY G  C   VS 
Sbjct: 427 YLCRCQAGFSGRHCD-DNVDDCASSPCANGGTC-RDGVNDFSCTCPPGYTGRNCSAPVS- 483

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N  +C
Sbjct: 484 --RCEHAPCHNGATC 496



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           CTCPPG+ G+ CE     C+    C NGGRC D+ +  Y+C C   GY+G  CE  ++ C
Sbjct: 352 CTCPPGFYGKICELSAMTCAD-GPCFNGGRCSDSPDGGYSCRC-PVGYSGFNCEKKIDYC 409

Query: 434 EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
               + C +G  C D    ++C CQ    G
Sbjct: 410 SS--SPCSNGAKCVDLGDAYLCRCQAGFSG 437



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C  D++ C+    C NG  C +    +YTC C   GYTGA CE  ++EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP-GYTGATCELGIDEC 332

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +      G G C D    + C C P   G
Sbjct: 333 DPSPCKNG-GSCTDLENSYSCTCPPGFYG 360



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           Y C C   Y+G NCE    D C+S+ C +GA+CV+ G   Y C C  G+ G +C+  V  
Sbjct: 389 YSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKCVDLGDA-YLCRCQAGFSGRHCDDNVDD 446

Query: 177 -SLDPLCVAGPCR---NNGSCSVPPG--GDTYSAPV 266
            +  P    G CR   N+ SC+ PPG  G   SAPV
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C  D         C++GA C   G+G Y+C C PGY G  CEL +  
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID- 330

Query: 183 DPLCVAGPCRNNGSCS 230
              C   PC+N GSC+
Sbjct: 331 --ECDPSPCKNGGSCT 344



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G  CE+ A   CA   C +G RC +   G YSC CP GY G  CE ++  
Sbjct: 350 YSCTCPPGFYGKICELSAMT-CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID- 407

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N   C
Sbjct: 408 --YCSSSPCSNGAKC 420



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           CTCPPGYTGRNC   V  C   A C NG  C +  + Y C+C A GY G  C+
Sbjct: 467 CTCPPGYTGRNCSAPVSRCE-HAPCHNGATCHERGHRYVCEC-ARGYGGPNCQ 517



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 22/55 (40%), Positives = 26/55 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   YTG NC       C  A C +GA C E G   Y C+C  GY G  C+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSR-CEHAPCHNGATCHERGH-RYVCECARGYGGPNCQ 517



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C    DEC     CL+G  C      + C+C   G+ G  C  ++N C 
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHG-TCQQP---WQCNCQE-GWGGLFCNQDLNYCT 293

Query: 437 EDRALCGHGVCYDT-YGGFVCACQPATPGST 526
             +       C +T  G + C+C+P   G+T
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 129 CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C C  G+ G YC+ E    P C+ G C+    C+   G
Sbjct: 243 CKCRVGWQGRYCD-ECIRYPGCLHGTCQQPWQCNCQEG 279


>AL078605-2|CAB89569.1|  723|Homo sapiens delta-like 1 (Drosophila)
           protein.
          Length = 723

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY+G NCE  +D CS ++ C NG +CVD  + Y C C A G++G  C+ NV++C 
Sbjct: 391 CRCPVGYSGFNCEKKIDYCS-SSPCSNGAKCVDLGDAYLCRCQA-GFSGRHCDDNVDDCA 448

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C C P   G
Sbjct: 449 SSPCANG-GTCRDGVNDFSCTCPPGYTG 475



 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G++GR+C+ +VD+C+ ++ C NGG C D VN+++C C   GYTG  C   V+ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCA-SSPCANGGTCRDGVNDFSCTC-PPGYTGRNCSAPVSRC 485

Query: 434 EEDRALCGHG-VCYDTYGGFVCAC 502
           E   A C +G  C++    +VC C
Sbjct: 486 E--HAPCHNGATCHERGHRYVCEC 507



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  CE+   D C  + C++G  C  D    YSC CPPG++G  CEL    
Sbjct: 312 YTCSCRPGYTGATCELGI-DECDPSPCKNGGSCT-DLENSYSCTCPPGFYGKICELSAM- 368

Query: 183 DPLCVAGPCRNNGSCS-VPPGGDTYSAPV 266
              C  GPC N G CS  P GG +   PV
Sbjct: 369 --TCADGPCFNGGRCSDSPDGGYSCRCPV 395



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +C+ D  D CAS+ C +G  C  DG  D+SC CPPGY G  C   VS 
Sbjct: 427 YLCRCQAGFSGRHCD-DNVDDCASSPCANGGTC-RDGVNDFSCTCPPGYTGRNCSAPVS- 483

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N  +C
Sbjct: 484 --RCEHAPCHNGATC 496



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           CTCPPG+ G+ CE     C+    C NGGRC D+ +  Y+C C   GY+G  CE  ++ C
Sbjct: 352 CTCPPGFYGKICELSAMTCAD-GPCFNGGRCSDSPDGGYSCRC-PVGYSGFNCEKKIDYC 409

Query: 434 EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
               + C +G  C D    ++C CQ    G
Sbjct: 410 SS--SPCSNGAKCVDLGDAYLCRCQAGFSG 437



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C  D++ C+    C NG  C +    +YTC C   GYTGA CE  ++EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP-GYTGATCELGIDEC 332

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +      G G C D    + C C P   G
Sbjct: 333 DPSPCKNG-GSCTDLENSYSCTCPPGFYG 360



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           Y C C   Y+G NCE    D C+S+ C +GA+CV+ G   Y C C  G+ G +C+  V  
Sbjct: 389 YSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKCVDLGDA-YLCRCQAGFSGRHCDDNVDD 446

Query: 177 -SLDPLCVAGPCR---NNGSCSVPPG--GDTYSAPV 266
            +  P    G CR   N+ SC+ PPG  G   SAPV
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C  D         C++GA C   G+G Y+C C PGY G  CEL +  
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID- 330

Query: 183 DPLCVAGPCRNNGSCS 230
              C   PC+N GSC+
Sbjct: 331 --ECDPSPCKNGGSCT 344



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G  CE+ A   CA   C +G RC +   G YSC CP GY G  CE ++  
Sbjct: 350 YSCTCPPGFYGKICELSAMT-CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID- 407

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N   C
Sbjct: 408 --YCSSSPCSNGAKC 420



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           CTCPPGYTGRNC   V  C   A C NG  C +  + Y C+C A GY G  C+
Sbjct: 467 CTCPPGYTGRNCSAPVSRCE-HAPCHNGATCHERGHRYVCEC-ARGYGGPNCQ 517



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 22/55 (40%), Positives = 26/55 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   YTG NC       C  A C +GA C E G   Y C+C  GY G  C+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSR-CEHAPCHNGATCHERGH-RYVCECARGYGGPNCQ 517



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C    DEC     CL+G  C      + C+C   G+ G  C  ++N C 
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHG-TCQQP---WQCNCQE-GWGGLFCNQDLNYCT 293

Query: 437 EDRALCGHGVCYDT-YGGFVCACQPATPGST 526
             +       C +T  G + C+C+P   G+T
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 129 CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C C  G+ G YC+ E    P C+ G C+    C+   G
Sbjct: 243 CKCRVGWQGRYCD-ECIRYPGCLHGTCQQPWQCNCQEG 279


>AF222310-1|AAG09716.1|  723|Homo sapiens Delta1 protein.
          Length = 723

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY+G NCE  +D CS ++ C NG +CVD  + Y C C A G++G  C+ NV++C 
Sbjct: 391 CRCPVGYSGFNCEKKIDYCS-SSPCSNGAKCVDLGDAYLCRCQA-GFSGRHCDDNVDDCA 448

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C C P   G
Sbjct: 449 SSPCANG-GTCRDGVNDFSCTCPPGYTG 475



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G++GR+C+ +VD+C+ ++ C NGG C D VN+++C C   GYTG  C   V+ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCA-SSPCANGGTCRDGVNDFSCTC-PPGYTGRNCSAPVSRC 485

Query: 434 EEDRALCGHG-VCYDTYGGFVCAC 502
           E   A C +G  C++   G+VC C
Sbjct: 486 E--HAPCHNGATCHERGHGYVCEC 507



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  CE+   D C  + C++G  C  D    YSC CPPG++G  CEL    
Sbjct: 312 YTCSCRPGYTGATCELGI-DECDPSPCKNGGSCT-DLENSYSCTCPPGFYGKICELSAM- 368

Query: 183 DPLCVAGPCRNNGSCS-VPPGGDTYSAPV 266
              C  GPC N G CS  P GG +   PV
Sbjct: 369 --TCADGPCFNGGRCSDSPDGGYSCRCPV 395



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +C+ D  D CAS+ C +G  C  DG  D+SC CPPGY G  C   VS 
Sbjct: 427 YLCRCQAGFSGRHCD-DNVDDCASSPCANGGTC-RDGVNDFSCTCPPGYTGRNCSAPVS- 483

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N  +C
Sbjct: 484 --RCEHAPCHNGATC 496



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           CTCPPG+ G+ CE     C+    C NGGRC D+ +  Y+C C   GY+G  CE  ++ C
Sbjct: 352 CTCPPGFYGKICELSAMTCAD-GPCFNGGRCSDSPDGGYSCRC-PVGYSGFNCEKKIDYC 409

Query: 434 EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
               + C +G  C D    ++C CQ    G
Sbjct: 410 SS--SPCSNGAKCVDLGDAYLCRCQAGFSG 437



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C  D++ C+    C NG  C +    +YTC C   GYTGA CE  ++EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP-GYTGATCELGIDEC 332

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +      G G C D    + C C P   G
Sbjct: 333 DPSPCKNG-GSCTDLENSYSCTCPPGFYG 360



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           Y C C   Y+G NCE    D C+S+ C +GA+CV+ G   Y C C  G+ G +C+  V  
Sbjct: 389 YSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKCVDLGDA-YLCRCQAGFSGRHCDDNVDD 446

Query: 177 -SLDPLCVAGPCR---NNGSCSVPPG--GDTYSAPV 266
            +  P    G CR   N+ SC+ PPG  G   SAPV
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C  D         C++GA C   G+G Y+C C PGY G  CEL +  
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID- 330

Query: 183 DPLCVAGPCRNNGSCS 230
              C   PC+N GSC+
Sbjct: 331 --ECDPSPCKNGGSCT 344



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G  CE+ A   CA   C +G RC +   G YSC CP GY G  CE ++  
Sbjct: 350 YSCTCPPGFYGKICELSAMT-CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID- 407

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N   C
Sbjct: 408 --YCSSSPCSNGAKC 420



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           CTCPPGYTGRNC   V  C   A C NG  C +  + Y C+C A GY G  C+
Sbjct: 467 CTCPPGYTGRNCSAPVSRCE-HAPCHNGATCHERGHGYVCEC-ARGYGGPNCQ 517



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/55 (41%), Positives = 27/55 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   YTG NC       C  A C +GA C E G G Y C+C  GY G  C+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSR-CEHAPCHNGATCHERGHG-YVCECARGYGGPNCQ 517



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C    DEC     CL+G  C      + C+C   G+ G  C  ++N C 
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHG-TCQQP---WQCNCQE-GWGGLFCNQDLNYCT 293

Query: 437 EDRALCGHGVCYDT-YGGFVCACQPATPGST 526
             +       C +T  G + C+C+P   G+T
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 129 CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C C  G+ G YC+ E    P C+ G C+    C+   G
Sbjct: 243 CKCRVGWQGRYCD-ECIRYPGCLHGTCQQPWQCNCQEG 279


>AF196571-1|AAF05834.1|  723|Homo sapiens Delta-like-1 protein
           protein.
          Length = 723

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY+G NCE  +D CS ++ C NG +CVD  + Y C C A G++G  C+ NV++C 
Sbjct: 391 CRCPVGYSGFNCEKKIDYCS-SSPCSNGAKCVDLGDAYLCRCQA-GFSGRHCDDNVDDCA 448

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C C P   G
Sbjct: 449 SSPCANG-GTCRDGVNDFSCTCPPGYTG 475



 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 36/84 (42%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G++GR+C+ +VD+C+ ++ C NGG C D VN+++C C   GYTG  C   V+ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCA-SSPCANGGTCRDGVNDFSCTC-PPGYTGRNCSAPVSRC 485

Query: 434 EEDRALCGHG-VCYDTYGGFVCAC 502
           E   A C +G  C+    G+VC C
Sbjct: 486 E--HAPCHNGATCHQRGHGYVCEC 507



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  CE+   D C  + C++G  C  D    YSC CPPG++G  CEL    
Sbjct: 312 YTCSCRPGYTGATCELGI-DECDPSPCKNGGSCT-DLENSYSCTCPPGFYGKICELSAM- 368

Query: 183 DPLCVAGPCRNNGSCS-VPPGGDTYSAPV 266
              C  GPC N G CS  P GG +   PV
Sbjct: 369 --TCADGPCFNGGRCSDSPDGGYSCRCPV 395



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +C+ D  D CAS+ C +G  C  DG  D+SC CPPGY G  C   VS 
Sbjct: 427 YLCRCQAGFSGRHCD-DNVDDCASSPCANGGTC-RDGVNDFSCTCPPGYTGRNCSAPVS- 483

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N  +C
Sbjct: 484 --RCEHAPCHNGATC 496



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           CTCPPG+ G+ CE     C+    C NGGRC D+ +  Y+C C   GY+G  CE  ++ C
Sbjct: 352 CTCPPGFYGKICELSAMTCAD-GPCFNGGRCSDSPDGGYSCRC-PVGYSGFNCEKKIDYC 409

Query: 434 EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
               + C +G  C D    ++C CQ    G
Sbjct: 410 SS--SPCSNGAKCVDLGDAYLCRCQAGFSG 437



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C  D++ C+    C NG  C +    +YTC C   GYTGA CE  ++EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP-GYTGATCELGIDEC 332

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +      G G C D    + C C P   G
Sbjct: 333 DPSPCKNG-GSCTDLENSYSCTCPPGFYG 360



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           Y C C   Y+G NCE    D C+S+ C +GA+CV+ G   Y C C  G+ G +C+  V  
Sbjct: 389 YSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKCVDLGDA-YLCRCQAGFSGRHCDDNVDD 446

Query: 177 -SLDPLCVAGPCR---NNGSCSVPPG--GDTYSAPV 266
            +  P    G CR   N+ SC+ PPG  G   SAPV
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C  D         C++GA C   G+G Y+C C PGY G  CEL +  
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID- 330

Query: 183 DPLCVAGPCRNNGSCS 230
              C   PC+N GSC+
Sbjct: 331 --ECDPSPCKNGGSCT 344



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G  CE+ A   CA   C +G RC +   G YSC CP GY G  CE ++  
Sbjct: 350 YSCTCPPGFYGKICELSAMT-CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID- 407

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N   C
Sbjct: 408 --YCSSSPCSNGAKC 420



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 26/53 (49%), Positives = 29/53 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           CTCPPGYTGRNC   V  C   A C NG  C    + Y C+C A  Y G  C+
Sbjct: 467 CTCPPGYTGRNCSAPVSRCE-HAPCHNGATCHQRGHGYVCEC-ARSYGGPNCQ 517



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 21/55 (38%), Positives = 26/55 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   YTG NC       C  A C +GA C + G G Y C+C   Y G  C+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSR-CEHAPCHNGATCHQRGHG-YVCECARSYGGPNCQ 517



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C    DEC     CL+G  C      + C+C   G+ G  C  ++N C 
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHG-TCQQP---WQCNCQE-GWGGLFCNQDLNYCT 293

Query: 437 EDRALCGHGVCYDT-YGGFVCACQPATPGST 526
             +       C +T  G + C+C+P   G+T
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 129 CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C C  G+ G YC+ E    P C+ G C+    C+   G
Sbjct: 243 CKCRVGWQGRYCD-ECIRYPGCLHGTCQQPWQCNCQEG 279


>AF003522-1|AAB61286.1|  723|Homo sapiens Delta protein.
          Length = 723

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 48/88 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP GY+G NCE  +D CS ++ C NG +CVD  + Y C C A G++G  C+ NV++C 
Sbjct: 391 CRCPVGYSGFNCEKKIDYCS-SSPCSNGAKCVDLGDAYLCRCQA-GFSGRHCDDNVDDCA 448

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G C D    F C C P   G
Sbjct: 449 SSPCANG-GTCRDGVNDFSCTCPPGYTG 475



 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  G++GR+C+ +VD+C+ ++ C NGG C D VN+++C C   GYTG  C   V+ C
Sbjct: 428 LCRCQAGFSGRHCDDNVDDCA-SSPCANGGTCRDGVNDFSCTC-PPGYTGRNCSAPVSRC 485

Query: 434 EEDRALCGHG-VCYDTYGGFVCAC 502
           E   A C +G  C++   G+VC C
Sbjct: 486 E--HAPCHNGATCHERGHGYVCEC 507



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  CE+   D C  + C++G  C  D    YSC CPPG++G  CEL    
Sbjct: 312 YTCSCRPGYTGATCELGI-DECDPSPCKNGGSCT-DLENSYSCTCPPGFYGKICELSAM- 368

Query: 183 DPLCVAGPCRNNGSCS-VPPGGDTYSAPV 266
              C  GPC N G CS  P GG +   PV
Sbjct: 369 --TCADGPCFNGGRCSDSPDGGYSCRCPV 395



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A ++G +C+ D  D CAS+ C +G  C  DG  D+SC CPPGY G  C   VS 
Sbjct: 427 YLCRCQAGFSGRHCD-DNVDDCASSPCANGGTC-RDGVNDFSCTCPPGYTGRNCSAPVS- 483

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N  +C
Sbjct: 484 --RCEHAPCHNGATC 496



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNEC 433
           CTCPPG+ G+ CE     C+    C NGGRC D+ +  Y+C C   GY+G  CE  ++ C
Sbjct: 352 CTCPPGFYGKICELSAMTCAD-GPCFNGGRCSDSPDGGYSCRC-PVGYSGFNCEKKIDYC 409

Query: 434 EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
               + C +G  C D    ++C CQ    G
Sbjct: 410 SS--SPCSNGAKCVDLGDAYLCRCQAGFSG 437



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C  D++ C+    C NG  C +    +YTC C   GYTGA CE  ++EC
Sbjct: 274 CNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRP-GYTGATCELGIDEC 332

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +      G G C D    + C C P   G
Sbjct: 333 DPSPCKNG-GSCTDLENSYSCTCPPGFYG 360



 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-- 176
           Y C C   Y+G NCE    D C+S+ C +GA+CV+ G   Y C C  G+ G +C+  V  
Sbjct: 389 YSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKCVDLGDA-YLCRCQAGFSGRHCDDNVDD 446

Query: 177 -SLDPLCVAGPCR---NNGSCSVPPG--GDTYSAPV 266
            +  P    G CR   N+ SC+ PPG  G   SAPV
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPV 482



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 28/76 (36%), Positives = 39/76 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C  D         C++GA C   G+G Y+C C PGY G  CEL +  
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID- 330

Query: 183 DPLCVAGPCRNNGSCS 230
              C   PC+N GSC+
Sbjct: 331 --ECDPSPCKNGGSCT 344



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G  CE+ A   CA   C +G RC +   G YSC CP GY G  CE ++  
Sbjct: 350 YSCTCPPGFYGKICELSAMT-CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKID- 407

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N   C
Sbjct: 408 --YCSSSPCSNGAKC 420



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           CTCPPGYTGRNC   V  C   A C NG  C +  + Y C+C A GY G  C+
Sbjct: 467 CTCPPGYTGRNCSAPVSRCE-HAPCHNGATCHERGHGYVCEC-ARGYGGPNCQ 517



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/55 (41%), Positives = 27/55 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   YTG NC       C  A C +GA C E G G Y C+C  GY G  C+
Sbjct: 465 FSCTCPPGYTGRNCSAPVSR-CEHAPCHNGATCHERGHG-YVCECARGYGGPNCQ 517



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C    DEC     CL+G  C      + C+C   G+ G  C  ++N C 
Sbjct: 243 CKCRVGWQGRYC----DECIRYPGCLHG-TCQQP---WQCNCQE-GWGGLFCNQDLNYCT 293

Query: 437 EDRALCGHGVCYDT-YGGFVCACQPATPGST 526
             +       C +T  G + C+C+P   G+T
Sbjct: 294 HHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/38 (34%), Positives = 18/38 (47%)
 Frame = +3

Query: 129 CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C C  G+ G YC+ E    P C+ G C+    C+   G
Sbjct: 243 CKCRVGWQGRYCD-ECIRYPGCLHGTCQQPWQCNCQEG 279


>AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.
          Length = 1097

 Score = 83.4 bits (197), Expect = 6e-16
 Identities = 37/88 (42%), Positives = 49/88 (55%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC   +TGRNCE+++  C     C NGG C    N + C+C A G TG  CE ++NECE
Sbjct: 554 CTCLSQFTGRNCESEITACF-PNPCRNGGSCDPIGNTFICNCKA-GLTGVTCEEDINECE 611

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +    G G C + +G F+C C P   G
Sbjct: 612 REECENG-GSCVNVFGSFLCNCTPGYVG 638



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 23/53 (43%), Positives = 30/53 (56%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
           +C C  G TG  CE D++EC     C NGG CV+   ++ C+CT  GY G  C
Sbjct: 591 ICNCKAGLTGVTCEEDINECE-REECENGGSCVNVFGSFLCNCT-PGYVGQYC 641



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/75 (34%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C +++TG NCE +    C    CR+G  C   G   + C+C  G  G  CE +++ 
Sbjct: 552 YQCTCLSQFTGRNCESEI-TACFPNPCRNGGSCDPIG-NTFICNCKAGLTGVTCEEDIN- 608

Query: 183 DPLCVAGPCRNNGSC 227
              C    C N GSC
Sbjct: 609 --ECEREECENGGSC 621



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/65 (38%), Positives = 32/65 (49%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C  + C+HG  C     G Y C C   + G  CE E++    C   PCRN GSC   P
Sbjct: 531 DACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEIT---ACFPNPCRNGGSCD--P 585

Query: 240 GGDTY 254
            G+T+
Sbjct: 586 IGNTF 590



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/65 (40%), Positives = 33/65 (50%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C+C A  TG  CE D  + C    C +G  CV +  G + C+C PGY G YC L   + P
Sbjct: 592 CNCKAGLTGVTCEEDINE-CEREECENGGSCV-NVFGSFLCNCTPGYVGQYCGLRPVVVP 649

Query: 189 LCVAG 203
              AG
Sbjct: 650 NIQAG 654



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
 Frame = +3

Query: 54  AGDPCASAACRHGARCV--EDGRGDYSCDCPPGYHGTYCELEVSL 182
           + DPC    C    +CV  E  R  + C CPPG  G  C    SL
Sbjct: 303 SNDPCVEKPCPGDMQCVGYEASRRPFLCQCPPGKLGE-CSGHTSL 346


>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
          Length = 1282

 Score = 83.0 bits (196), Expect = 8e-16
 Identities = 42/86 (48%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C  GYTG  CE DVD+CS    CLNGG CVD V NYTC C A  + G RCET  +  
Sbjct: 241 VCVCQAGYTGAACEMDVDDCS-PDPCLNGGSCVDLVGNYTCLC-AEPFKGLRCETGDHPV 298

Query: 434 EED--RALCGH-GVCYDTYGGFVCAC 502
            +    A C + G C D   G+VC C
Sbjct: 299 PDACLSAPCHNGGTCVDADQGYVCEC 324



 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 34/75 (45%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C  R+TG +CE+   D CAS  C +G  C     G Y CDCPPG+ G +CE+  S 
Sbjct: 471 YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFH-YIGKYKCDCPPGFSGRHCEIAPS- 528

Query: 183 DPLCVAGPCRNNGSC 227
            P C   PC N G+C
Sbjct: 529 -P-CFRSPCVNGGTC 541



 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 37/90 (41%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C  G+TGR C  DV+EC+ +  C NGG C   +N++ C C A G+ G  CET  + C 
Sbjct: 166 CSCLSGFTGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPA-GFGGPTCETAQSPC- 222

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
            D   C H G C    G  VC CQ    G+
Sbjct: 223 -DTKECQHGGQCQVENGSAVCVCQAGYTGA 251



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/84 (42%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GY G +CE + DEC  A  C NGG C +    Y C C A G+ G  CET V+ C
Sbjct: 645 LCLCSTGYEGAHCELERDECR-AHPCRNGGSCRNLPGAYVCRCPA-GFVGVHCETEVDAC 702

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
             D + C H G C    G ++C C
Sbjct: 703 --DSSPCQHGGRCESGGGAYLCVC 724



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A + G +CE +  D C S+ C+HG RC E G G Y C CP  + G +CE  VS 
Sbjct: 682 YVCRCPAGFVGVHCETEV-DACDSSPCQHGGRC-ESGGGAYLCVCPESFFGYHCE-TVS- 737

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPV 266
           DP C + PC   G C    G  + +  V
Sbjct: 738 DP-CFSSPCGGRGYCLASNGSHSCTCKV 764



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 29/75 (38%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +CE      C+S  CR+G  C E G G+Y C CP  + G +C  E+  
Sbjct: 432 YTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAG-GEYHCSCPYRFTGRHC--EIGK 488

Query: 183 DPLCVAGPCRNNGSC 227
              C +GPC N G+C
Sbjct: 489 PDSCASGPCHNGGTC 503



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 31/88 (35%), Positives = 41/88 (46%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP  +TGR+CE    +   +  C NGG C   +  Y CDC   G++G  CE   + C 
Sbjct: 473 CSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDC-PPGFSGRHCEIAPSPCF 531

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               + G G C D    F C CQ    G
Sbjct: 532 RSPCVNG-GTCEDRDTDFFCHCQAGYMG 558



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
           Y C C   +T +N       PC S  C +G  C  D   D Y+C+CP G+HG +CE   +
Sbjct: 396 YLCVC---HTDHNASHSLPSPCDSDPCFNGGSC--DAHDDSYTCECPRGFHGKHCEK--A 448

Query: 180 LDPLCVAGPCRNNGSCSVPPGGDTYSAPVR 269
              LC +GPCRN G+C    G    S P R
Sbjct: 449 RPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 478



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 32/84 (38%), Positives = 44/84 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  Y G +CE++  D C +  CR+G  C  +  G Y C CP G+ G +CE EV  
Sbjct: 644 YLCLCSTGYEGAHCELER-DECRAHPCRNGGSC-RNLPGAYVCRCPAGFVGVHCETEVD- 700

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
              C + PC++ G C    GG  Y
Sbjct: 701 --ACDSSPCQHGGRCE--SGGGAY 720



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 31/89 (34%), Positives = 43/89 (48%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CP G+ G +CET+VD C  ++ C +GGRC      Y C C  + + G  CET  + C
Sbjct: 683 VCRCPAGFVGVHCETEVDACD-SSPCQHGGRCESGGGAYLCVCPES-FFGYHCETVSDPC 740

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C  + G   C C+    G
Sbjct: 741 FSS-PCGGRGYCLASNGSHSCTCKVGYTG 768



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/75 (40%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A + G  CE  A  PC +  C+HG +C  +  G   C C  GY G  CE++V  
Sbjct: 202 FRCQCPAGFGGPTCET-AQSPCDTKECQHGGQCQVEN-GSAVCVCQAGYTGAACEMDVD- 258

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N GSC
Sbjct: 259 D--CSPDPCLNGGSC 271



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 29/80 (36%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C + +TG  C +D  + CAS  C++G  C   G   + C CP G+ G  CE   S 
Sbjct: 164 YTCSCLSGFTGRRCHLDVNE-CASQPCQNGGTCTH-GINSFRCQCPAGFGGPTCETAQS- 220

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
            P C    C++ G C V  G
Sbjct: 221 -P-CDTKECQHGGQCQVENG 238



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 29/74 (39%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVSLD 185
           C C A YTG  CE+D  D C+   C +G  CV D  G+Y+C C   + G  CE  +  + 
Sbjct: 242 CVCQAGYTGAACEMDV-DDCSPDPCLNGGSCV-DLVGNYTCLCAEPFKGLRCETGDHPVP 299

Query: 186 PLCVAGPCRNNGSC 227
             C++ PC N G+C
Sbjct: 300 DACLSAPCHNGGTC 313



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/88 (30%), Positives = 36/88 (40%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G++CE        +  C NGG C +A   Y C C    +TG  CE    +  
Sbjct: 434 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR-FTGRHCEIGKPDSC 492

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C+   G + C C P   G
Sbjct: 493 ASGPCHNGGTCFHYIGKYKCDCPPGFSG 520



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/68 (42%), Positives = 37/68 (54%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDT 478
           ++DEC  +  CL+GG C D V  Y C C +TGY GA CE   +EC       G G C + 
Sbjct: 622 EIDECR-SQPCLHGGSCQDRVAGYLCLC-STGYEGAHCELERDECRAHPCRNG-GSCRNL 678

Query: 479 YGGFVCAC 502
            G +VC C
Sbjct: 679 PGAYVCRC 686



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/68 (44%), Positives = 32/68 (47%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C S  C HG  C +D    Y C C  GY G +CELE      C A PCRN GSC   P
Sbjct: 624 DECRSQPCLHGGSC-QDRVAGYLCLCSTGYEGAHCELE---RDECRAHPCRNGGSCRNLP 679

Query: 240 GGDTYSAP 263
           G      P
Sbjct: 680 GAYVCRCP 687



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVD--AVNN--YTCDCTATGYTGARCETNVNECEEDRALCG 457
           C      C     CLNGG+C+D     N  YTC C  +G+TG RC  +VNEC       G
Sbjct: 134 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSC-LSGFTGRRCHLDVNECASQPCQNG 192

Query: 458 HGVCYDTYGGFVCACQPATPGST 526
            G C      F C C     G T
Sbjct: 193 -GTCTHGINSFRCQCPAGFGGPT 214



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 33/62 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G +CE+ A  PC  + C +G  C ED   D+ C C  GY G  C+ EV  
Sbjct: 510 YKCDCPPGFSGRHCEI-APSPCFRSPCVNGGTC-EDRDTDFFCHCQAGYMGRRCQAEVDC 567

Query: 183 DP 188
            P
Sbjct: 568 GP 569



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD---AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G  CE       D C SA C +G  CV+  +G Y C+CP G+ G  C   
Sbjct: 278 YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG-YVCECPEGFMGLDCRER 336

Query: 174 VSLDPLCVAGPCRNNGSC 227
           V  D  C    CRN G C
Sbjct: 337 VPDD--C---ECRNGGRC 349



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN- 427
           +C CP G+ G +C   V D+C     C NGGRC+ A N   C C   G+ G  CE  +  
Sbjct: 321 VCECPEGFMGLDCRERVPDDCE----CRNGGRCLGA-NTTLCQC-PLGFFGLLCEFEITA 374

Query: 428 -ECEEDRALCGHGVCYDTYGGFVCAC 502
             C  +      G C +  G ++C C
Sbjct: 375 MPCNMNTQCPDGGYCMEHGGSYLCVC 400



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +C     D C    CR+G RC+  G     C CP G+ G  CE E++ 
Sbjct: 320 YVCECPEGFMGLDCRERVPDDCE---CRNGGRCL--GANTTLCQCPLGFFGLLCEFEITA 374

Query: 183 DPLCVAGPCRNNGSC 227
            P  +   C + G C
Sbjct: 375 MPCNMNTQCPDGGYC 389



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +3

Query: 81  CRHGARCVED---GRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           C +G +C++D   G   Y+C C  G+ G  C L+V+    C + PC+N G+C+
Sbjct: 147 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVN---ECASQPCQNGGTCT 196



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNE 430
           LC C   +T  N    +     +  C NGG C    ++YTC+C   G+ G  CE    + 
Sbjct: 397 LCVC---HTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCEC-PRGFHGKHCEKARPHL 452

Query: 431 CEEDRALCGHGVCYDTYGGFVCAC 502
           C       G G C +  G + C+C
Sbjct: 453 CSSGPCRNG-GTCKEAGGEYHCSC 475



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVD--ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           LC CP G+ G  CE ++    C+    C +GG C++   +Y C C  T +  +   +  +
Sbjct: 356 LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNAS--HSLPS 412

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
            C+ D    G G C      + C C
Sbjct: 413 PCDSDPCFNG-GSCDAHDDSYTCEC 436



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            C+   C++G  CV  G   +SCDC PG+ G  CEL
Sbjct: 1180 CSENPCQNGGTCVP-GADAHSCDCGPGFKGRRCEL 1213



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 34/115 (29%), Positives = 43/115 (37%), Gaps = 20/115 (17%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVD-----ECSGAAACLNGGRCVDAVNNYTCD-------- 379
           R     C C  GY GR C+ +VD     E   A    NG R + AV  Y CD        
Sbjct: 544 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR-LGAVALYACDRGYSLSAP 602

Query: 380 -----CTATGYTG--ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
                C   G      +C   ++EC     L G G C D   G++C C     G+
Sbjct: 603 SRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHG-GSCQDRVAGYLCLCSTGYEGA 655



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 21/64 (32%), Positives = 31/64 (48%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            ++ AP+R  L    P  +  ++       CS    C NGG CV   + ++CDC   G+ G
Sbjct: 1152 MEEAPKRVSLALQLPE-HGSKDIGNVPGNCS-ENPCQNGGTCVPGADAHSCDC-GPGFKG 1208

Query: 404  ARCE 415
             RCE
Sbjct: 1209 RRCE 1212


>BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.
          Length = 647

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 37/89 (41%), Positives = 47/89 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
            D    G   C D  G F C C     GS
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTGS 622



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
           sequence DNA binding protein-1 protein.
          Length = 1008

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 35/75 (46%), Positives = 42/75 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C  R+TG +CE+   D CAS  C +G  C     G Y CDCPPG+ G YCE+  S 
Sbjct: 217 YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFH-YIGKYKCDCPPGFSGRYCEIAPS- 274

Query: 183 DPLCVAGPCRNNGSC 227
            P C   PC N G+C
Sbjct: 275 -P-CFRSPCVNGGTC 287



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/84 (42%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C  GY G +CE + DEC  A  C NGG C +    Y C C A G+ G  CET V+ C
Sbjct: 391 LCLCSTGYEGAHCELERDECR-AHPCRNGGSCRNLPGAYVCRCPA-GFVGVHCETEVDAC 448

Query: 434 EEDRALCGH-GVCYDTYGGFVCAC 502
             D + C H G C    G ++C C
Sbjct: 449 --DSSPCQHGGRCESGGGAYLCVC 470



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 37/88 (42%), Positives = 47/88 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A + G +CE +  D C S+ C+HG RC E G G Y C CP G+ G +CE  VS 
Sbjct: 428 YVCRCPAGFVGVHCETEV-DACDSSPCQHGGRC-ESGGGAYLCVCPEGFFGYHCE-TVS- 483

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPV 266
           DP C + PC   G C    G  + +  V
Sbjct: 484 DP-CFSSPCGGRGYCLASNGSHSCTCKV 510



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 29/75 (38%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +CE      C+S  CR+G  C E G G+Y C CP  + G +C  E+  
Sbjct: 178 YTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAG-GEYHCSCPYRFTGRHC--EIGK 234

Query: 183 DPLCVAGPCRNNGSC 227
              C +GPC N G+C
Sbjct: 235 PDSCASGPCHNGGTC 249



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 31/88 (35%), Positives = 41/88 (46%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP  +TGR+CE    +   +  C NGG C   +  Y CDC   G++G  CE   + C 
Sbjct: 219 CSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDC-PPGFSGRYCEIAPSPCF 277

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               + G G C D    F C CQ    G
Sbjct: 278 RSPCVNG-GTCEDRDTDFFCHCQAGYMG 304



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 32/89 (35%), Positives = 43/89 (48%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CP G+ G +CET+VD C  ++ C +GGRC      Y C C   G+ G  CET  + C
Sbjct: 429 VCRCPAGFVGVHCETEVDACD-SSPCQHGGRCESGGGAYLCVC-PEGFFGYHCETVSDPC 486

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C  + G   C C+    G
Sbjct: 487 FSS-PCGGRGYCLASNGSHSCTCKVGYTG 514



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVS 179
           Y C C   +T +N       PC S  C +G  C  D   D Y+C+CP G+HG +CE   +
Sbjct: 142 YLCVC---HTDHNASHSLPSPCNSDPCFNGGSC--DAHDDSYTCECPRGFHGKHCEK--A 194

Query: 180 LDPLCVAGPCRNNGSCSVPPGGDTYSAPVR 269
              LC +GPCRN G+C    G    S P R
Sbjct: 195 RPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 224



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 32/84 (38%), Positives = 44/84 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C+  Y G +CE++  D C +  CR+G  C  +  G Y C CP G+ G +CE EV  
Sbjct: 390 YLCLCSTGYEGAHCELER-DECRAHPCRNGGSC-RNLPGAYVCRCPAGFVGVHCETEVD- 446

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTY 254
              C + PC++ G C    GG  Y
Sbjct: 447 --ACDSSPCQHGGRCE--SGGGAY 466



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 34/71 (47%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEED--RALCGH-GVC 469
           DVD+CS    CLNGG CVD V NYTC C A  + G RCET  +   +    A C + G C
Sbjct: 2   DVDDCS-PDPCLNGGSCVDLVGNYTCLC-AEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59

Query: 470 YDTYGGFVCAC 502
            D   G+VC C
Sbjct: 60  VDADQGYVCEC 70



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/88 (30%), Positives = 36/88 (40%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G++CE        +  C NGG C +A   Y C C    +TG  CE    +  
Sbjct: 180 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR-FTGRHCEIGKPDSC 238

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                   G C+   G + C C P   G
Sbjct: 239 ASGPCHNGGTCFHYIGKYKCDCPPGFSG 266



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 29/68 (42%), Positives = 37/68 (54%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDT 478
           ++DEC  +  CL+GG C D V  Y C C +TGY GA CE   +EC       G G C + 
Sbjct: 368 EIDECR-SQPCLHGGSCQDRVAGYLCLC-STGYEGAHCELERDECRAHPCRNG-GSCRNL 424

Query: 479 YGGFVCAC 502
            G +VC C
Sbjct: 425 PGAYVCRC 432



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/68 (44%), Positives = 32/68 (47%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C S  C HG  C +D    Y C C  GY G +CELE      C A PCRN GSC   P
Sbjct: 370 DECRSQPCLHGGSC-QDRVAGYLCLCSTGYEGAHCELE---RDECRAHPCRNGGSCRNLP 425

Query: 240 GGDTYSAP 263
           G      P
Sbjct: 426 GAYVCRCP 433



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/78 (38%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVD---AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   + G  CE       D C SA C +G  CV+  +G Y C+CP G+ G  C   
Sbjct: 24  YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQG-YVCECPEGFMGLDCRER 82

Query: 174 VSLDPLCVAGPCRNNGSC 227
           V  D  C    CRN G C
Sbjct: 83  VPDD--C---ECRNGGRC 95



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 24/62 (38%), Positives = 32/62 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   ++G  CE+ A  PC  + C +G  C ED   D+ C C  GY G  C+ EV  
Sbjct: 256 YKCDCPPGFSGRYCEI-APSPCFRSPCVNGGTC-EDRDTDFFCHCQAGYMGRRCQAEVDC 313

Query: 183 DP 188
            P
Sbjct: 314 GP 315



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN- 427
           +C CP G+ G +C   V D+C     C NGGRC+ A N   C C   G+ G  CE  +  
Sbjct: 67  VCECPEGFMGLDCRERVPDDCE----CRNGGRCLGA-NTTLCQC-PLGFFGLLCEFEITA 120

Query: 428 -ECEEDRALCGHGVCYDTYGGFVCAC 502
             C  +      G C +  G ++C C
Sbjct: 121 MPCNMNTQCPDGGYCMEHGGSYLCVC 146



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 25/75 (33%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +C     D C    CR+G RC+  G     C CP G+ G  CE E++ 
Sbjct: 66  YVCECPEGFMGLDCRERVPDDCE---CRNGGRCL--GANTTLCQCPLGFFGLLCEFEITA 120

Query: 183 DPLCVAGPCRNNGSC 227
            P  +   C + G C
Sbjct: 121 MPCNMNTQCPDGGYC 135



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL-EVSLDPLCVAGPCRNNGSC 227
           D C+   C +G  CV D  G+Y+C C   + G  CE  +  +   C++ PC N G+C
Sbjct: 4   DDCSPDPCLNGGSCV-DLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 59



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNE 430
           LC C   +T  N    +     +  C NGG C    ++YTC+C   G+ G  CE    + 
Sbjct: 143 LCVC---HTDHNASHSLPSPCNSDPCFNGGSCDAHDDSYTCEC-PRGFHGKHCEKARPHL 198

Query: 431 CEEDRALCGHGVCYDTYGGFVCAC 502
           C       G G C +  G + C+C
Sbjct: 199 CSSGPCRNG-GTCKEAGGEYHCSC 221



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            C+   C++G  CV  G   +SCDC PG+ G  CEL
Sbjct: 906  CSENPCQNGGTCVP-GADAHSCDCGPGFKGRRCEL 939



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVD--ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           LC CP G+ G  CE ++    C+    C +GG C++   +Y C C  T +  +   +  +
Sbjct: 102 LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVC-HTDHNAS--HSLPS 158

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
            C  D    G G C      + C C
Sbjct: 159 PCNSDPCFNG-GSCDAHDDSYTCEC 182



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 21/64 (32%), Positives = 31/64 (48%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
            ++ AP+R  L    P  +  ++       CS    C NGG CV   + ++CDC   G+ G
Sbjct: 878  MEEAPKRVSLALQLPE-HGSKDIGNVPGNCS-ENPCQNGGTCVPGADAHSCDC-GPGFKG 934

Query: 404  ARCE 415
             RCE
Sbjct: 935  RRCE 938



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 20/115 (17%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVD-----ECSGAAACLNGGRCVDAVNNYTCD-------- 379
           R     C C  GY GR C+ +VD     E   A    NG R + A   Y CD        
Sbjct: 290 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTR-LGAAALYACDRGYSLSAP 348

Query: 380 -----CTATGYTG--ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
                C   G      +C   ++EC     L G G C D   G++C C     G+
Sbjct: 349 SRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHG-GSCQDRVAGYLCLCSTGYEGA 401


>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
          Length = 1223

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 607 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 664

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 665 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 693



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 760  CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 817

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                 C +G  C D   G+ C+C P   G
Sbjct: 818  SSP--CAYGATCVDEINGYRCSCPPGRAG 844



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC-ETNVNEC 433
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C  +G++G  C   +++EC
Sbjct: 317 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHC-PSGWSGPTCASADIDEC 374

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C D   GF C C     G+T
Sbjct: 375 ASNPCAAG-GTCVDQVDGFECICPEQWVGAT 404



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + DEC+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 469 CVCPRGFGGRHCELERDECA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 526

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 527 P--SPCRNGARCYNLEGDYYCAC 547



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 35/88 (39%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G NC  +V++C G   C +GG C D VN Y C C   G+ G  CE   +EC 
Sbjct: 432 CDCIPGWKGINCHINVNDCRG--QCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDECA 488

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 489 SSPCHSG-GLCEDLADGFHCHCPQGFSG 515



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 34/89 (38%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP G++G  C + D+DEC+ +  C  GG CVD V+ + C C    + GA C+ + NEC
Sbjct: 355 CHCPSGWSGPTCASADIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDANEC 412

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E    L     C +  GG+ C C P   G
Sbjct: 413 EGKPCLNAFS-CKNLIGGYYCDCIPGWKG 440



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 645 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 701

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 702 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 731



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 467 YQCVCPRGFGGRHCELER-DECASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 523

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 524 --LCEPSPCRNGARC-YNLEGDYYCA 546



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 721 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 779

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 780 PLPCYNG-GICVDGVNWFRCECAPGFAG 806



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 277 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 335

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 336 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 365



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 505 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 560

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 561 EP-CPGGACRVIDGCGSDAG 579



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 275 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 331

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 332 EHACTSNPCANGGSCHEVPSG 352



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/81 (35%), Positives = 39/81 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C     D CAS  C  G  CV+   G + C CP  + G  C+L+ + 
Sbjct: 353 FECHCPSGWSGPTCASADIDECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDAN- 410

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C   PC N  SC    GG
Sbjct: 411 --ECEGKPCLNAFSCKNLIGG 429



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 798 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 848



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 683 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 740

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 741 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 772



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 796 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 853

Query: 183 DPLC 194
              C
Sbjct: 854 GRSC 857



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 572 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 628

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 629 PCRNGGTC 636



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C  ++ G  C++DA + C    C +   C ++  G Y CDC PG+ G  C + V+ 
Sbjct: 392 FECICPEQWVGATCQLDANE-CEGKPCLNAFSC-KNLIGGYYCDCIPGWKGINCHINVN- 448

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 449 D--C-RGQCQHGGTC 460



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 605 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 661

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 662 D--CLPDPCHSRGRC 674



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 681 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 736

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 737 NSSCLPNPCVNGGTC 751



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 758  FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 814

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC    +C     G   S P
Sbjct: 815  --ECQSSPCAYGATCVDEINGYRCSCP 839



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 719 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 776

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 777 D--CNPLPCYNGGIC 789



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 545 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 604

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 605 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 653


>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
          Length = 1238

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 622 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 679

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 680 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 708



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C + G++G  C  +++EC 
Sbjct: 333 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHCPS-GWSGPTCALDIDECA 390

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +    G G C D   GF C C     G+T
Sbjct: 391 SNPCAAG-GTCVDQVDGFECICPEQWVGAT 419



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 775  CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 832

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                 C +G  C D   G+ C+C P   G
Sbjct: 833  SSP--CAYGATCVDEINGYRCSCPPGRAG 859



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G++G  C  D+DEC+ +  C  GG CVD V+ + C C    + GA C+ + NECE
Sbjct: 371 CHCPSGWSGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDANECE 428

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L     C +  GG+ C C P   G
Sbjct: 429 GKPCLNAFS-CKNLIGGYYCDCIPGWKG 455



 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + DEC+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 484 CVCPRGFGGRHCELERDECA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 541

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 542 P--SPCRNGARCYNLEGDYYCAC 562



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 35/88 (39%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G NC  +V++C G   C +GG C D VN Y C C   G+ G  CE   +EC 
Sbjct: 447 CDCIPGWKGINCHINVNDCRG--QCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDECA 503

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 504 SSPCHSG-GLCEDLADGFHCHCPQGFSG 530



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 660 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 716

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 717 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 746



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 482 YQCVCPRGFGGRHCELER-DECASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 538

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 539 --LCEPSPCRNGARC-YNLEGDYYCA 561



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 794

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 795 PLPCYNG-GICVDGVNWFRCECAPGFAG 821



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 293 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 351

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 352 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 381



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 520 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 575

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 576 EP-CPGGACRVIDGCGSDAG 594



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 347

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 348 EHACTSNPCANGGSCHEVPSG 368



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/81 (37%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C +D  D CAS  C  G  CV+   G + C CP  + G  C+L+ + 
Sbjct: 369 FECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDAN- 425

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C   PC N  SC    GG
Sbjct: 426 --ECEGKPCLNAFSCKNLIGG 444



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 813 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 863



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 698 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 755

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 787



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 811 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 868

Query: 183 DPLC 194
              C
Sbjct: 869 GRSC 872



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 643

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 644 PCRNGGTC 651



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C  ++ G  C++DA + C    C +   C ++  G Y CDC PG+ G  C + V+ 
Sbjct: 407 FECICPEQWVGATCQLDANE-CEGKPCLNAFSC-KNLIGGYYCDCIPGWKGINCHINVN- 463

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 464 D--C-RGQCQHGGTC 475



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 620 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 676

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 677 D--CLPDPCHSRGRC 689



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 696 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 751

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 752 NSSCLPNPCVNGGTC 766



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 773  FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 829

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC    +C     G   S P
Sbjct: 830  --ECQSSPCAYGATCVDEINGYRCSCP 854



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 734 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 791

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 792 D--CNPLPCYNGGIC 804



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 560 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 619

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 620 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 668


>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
          Length = 1200

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 584 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 641

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 642 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 670



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C + G++G  C  +++EC 
Sbjct: 333 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHCPS-GWSGPTCALDIDECA 390

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +    G G C D   GF C C     G+T
Sbjct: 391 SNPCAAG-GTCVDQVDGFECICPEQWVGAT 419



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 737 CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 794

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                C +G  C D   G+ C+C P   G
Sbjct: 795 SSP--CAYGATCVDEINGYRCSCPPGRAG 821



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G++G  C  D+DEC+ +  C  GG CVD V+ + C C    + GA C+ +VN+C 
Sbjct: 371 CHCPSGWSGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDVNDC- 427

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
             R  C H G C D   G+ C C
Sbjct: 428 --RGQCQHGGTCKDLVNGYQCVC 448



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + D+C+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 446 CVCPRGFGGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 503

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 504 P--SPCRNGARCYNLEGDYYCAC 524



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 622 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 678

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 679 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 708



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/88 (37%), Positives = 42/88 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP  + G  C+ DV++C G   C +GG C D VN Y C C   G+ G  CE   ++C 
Sbjct: 409 CICPEQWVGATCQLDVNDCRGQ--CQHGGTCKDLVNGYQCVCPR-GFGGRHCELERDKCA 465

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 466 SSPCHSG-GLCEDLADGFHCHCPQGFSG 492



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 444 YQCVCPRGFGGRHCELER-DKCASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 500

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 501 --LCEPSPCRNGARC-YNLEGDYYCA 523



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 698 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 756

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 757 PLPCYNG-GICVDGVNWFRCECAPGFAG 783



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 293 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 351

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 352 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 381



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 482 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 537

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 538 EP-CPGGACRVIDGCGSDAG 556



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 347

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 348 EHACTSNPCANGGSCHEVPSG 368



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 29/75 (38%), Positives = 43/75 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C +D  D CAS  C  G  CV+   G + C CP  + G  C+L+V+ 
Sbjct: 369 FECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDVN- 425

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 426 D--C-RGQCQHGGTC 437



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 775 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 825



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 660 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 717

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 718 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 749



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 773 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 830

Query: 183 DPLC 194
              C
Sbjct: 831 GRSC 834



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 549 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 605

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 606 PCRNGGTC 613



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 582 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 638

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 639 D--CLPDPCHSRGRC 651



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 658 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 713

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 714 NSSCLPNPCVNGGTC 728



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 735 FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 791

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC    +C     G   S P
Sbjct: 792 --ECQSSPCAYGATCVDEINGYRCSCP 816



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 696 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 753

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 754 D--CNPLPCYNGGIC 766



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 522 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 581

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 582 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 630


>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
          Length = 1238

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 622 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 679

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 680 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 708



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C + G++G  C  +++EC 
Sbjct: 333 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHCPS-GWSGPTCALDIDECA 390

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +    G G C D   GF C C     G+T
Sbjct: 391 SNPCAAG-GTCVDQVDGFECICPEQWVGAT 419



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 775  CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 832

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                 C +G  C D   G+ C+C P   G
Sbjct: 833  SSP--CAYGATCVDEINGYRCSCPPGRAG 859



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G++G  C  D+DEC+ +  C  GG CVD V+ + C C    + GA C+ + NECE
Sbjct: 371 CHCPSGWSGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDANECE 428

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L     C +  GG+ C C P   G
Sbjct: 429 GKPCLNAFS-CKNLIGGYYCDCIPGWKG 455



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + D+C+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 484 CVCPRGFGGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 541

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 542 P--SPCRNGARCYNLEGDYYCAC 562



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 660 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 716

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 717 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 746



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 34/88 (38%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G NC  +V++C G   C +GG C D VN Y C C   G+ G  CE   ++C 
Sbjct: 447 CDCIPGWKGINCHINVNDCRG--QCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDKCA 503

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 504 SSPCHSG-GLCEDLADGFHCHCPQGFSG 530



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 482 YQCVCPRGFGGRHCELER-DKCASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 538

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 539 --LCEPSPCRNGARC-YNLEGDYYCA 561



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 794

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 795 PLPCYNG-GICVDGVNWFRCECAPGFAG 821



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 293 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 351

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 352 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 381



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 520 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 575

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 576 EP-CPGGACRVIDGCGSDAG 594



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 347

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 348 EHACTSNPCANGGSCHEVPSG 368



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/81 (37%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C +D  D CAS  C  G  CV+   G + C CP  + G  C+L+ + 
Sbjct: 369 FECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDAN- 425

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C   PC N  SC    GG
Sbjct: 426 --ECEGKPCLNAFSCKNLIGG 444



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 813 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 863



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 698 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 755

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 787



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 811 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 868

Query: 183 DPLC 194
              C
Sbjct: 869 GRSC 872



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 643

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 644 PCRNGGTC 651



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C  ++ G  C++DA + C    C +   C ++  G Y CDC PG+ G  C + V+ 
Sbjct: 407 FECICPEQWVGATCQLDANE-CEGKPCLNAFSC-KNLIGGYYCDCIPGWKGINCHINVN- 463

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 464 D--C-RGQCQHGGTC 475



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 620 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 676

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 677 D--CLPDPCHSRGRC 689



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 696 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 751

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 752 NSSCLPNPCVNGGTC 766



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 773  FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 829

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC    +C     G   S P
Sbjct: 830  --ECQSSPCAYGATCVDEINGYRCSCP 854



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 734 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 791

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 792 D--CNPLPCYNGGIC 804



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 560 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 619

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 620 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 668


>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
          Length = 1238

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 622 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 679

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 680 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 708



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C + G++G  C  +++EC 
Sbjct: 333 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHCPS-GWSGPTCALDIDECA 390

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +    G G C D   GF C C     G+T
Sbjct: 391 SNPCAAG-GTCVDQVDGFECICPEQWVGAT 419



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 775  CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 832

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                 C +G  C D   G+ C+C P   G
Sbjct: 833  SSP--CAYGATCVDEINGYRCSCPPGRAG 859



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/88 (38%), Positives = 47/88 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G++G  C  D+DEC+ +  C  GG CVD V+ + C C    + GA C+ +VN+CE
Sbjct: 371 CHCPSGWSGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDVNDCE 428

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L     C +  GG+ C C P   G
Sbjct: 429 GKPCLNAFS-CKNLIGGYYCDCIPGWKG 455



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + D+C+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 484 CVCPRGFGGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 541

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 542 P--SPCRNGARCYNLEGDYYCAC 562



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 660 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 716

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 717 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 746



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 34/88 (38%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G NC  +V++C G   C +GG C D VN Y C C   G+ G  CE   ++C 
Sbjct: 447 CDCIPGWKGINCHINVNDCRG--QCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDKCA 503

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 504 SSPCHSG-GLCEDLADGFHCHCPQGFSG 530



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 482 YQCVCPRGFGGRHCELER-DKCASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 538

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 539 --LCEPSPCRNGARC-YNLEGDYYCA 561



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 794

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 795 PLPCYNG-GICVDGVNWFRCECAPGFAG 821



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 293 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 351

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 352 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 381



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 520 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 575

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 576 EP-CPGGACRVIDGCGSDAG 594



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 347

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 348 EHACTSNPCANGGSCHEVPSG 368



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 32/81 (39%), Positives = 43/81 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C +D  D CAS  C  G  CV+   G + C CP  + G  C+L+V+ 
Sbjct: 369 FECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDVN- 425

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C   PC N  SC    GG
Sbjct: 426 D--CEGKPCLNAFSCKNLIGG 444



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 813 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 863



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 698 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 755

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 787



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 811 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 868

Query: 183 DPLC 194
              C
Sbjct: 869 GRSC 872



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 643

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 644 PCRNGGTC 651



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 40/75 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C  ++ G  C++D  D C    C +   C ++  G Y CDC PG+ G  C + V+ 
Sbjct: 407 FECICPEQWVGATCQLDVND-CEGKPCLNAFSC-KNLIGGYYCDCIPGWKGINCHINVN- 463

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 464 D--C-RGQCQHGGTC 475



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 620 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 676

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 677 D--CLPDPCHSRGRC 689



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 696 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 751

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 752 NSSCLPNPCVNGGTC 766



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 773  FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 829

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC    +C     G   S P
Sbjct: 830  --ECQSSPCAYGATCVDEINGYRCSCP 854



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 734 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 791

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 792 D--CNPLPCYNGGIC 804



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 560 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 619

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 620 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 668


>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
          Length = 1238

 Score = 81.0 bits (191), Expect = 3e-15
 Identities = 36/90 (40%), Positives = 47/90 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  C  ++D+C G   C NGG C+D V+ + C C  +G+ G  C+TN N+C 
Sbjct: 622 CICDSGFTGTYCHENIDDCLG-QPCRNGGTCIDEVDAFRCFC-PSGWEGELCDTNPNDCL 679

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            D      G CYD    F CAC     G T
Sbjct: 680 PD-PCHSRGRCYDLVNDFYCACDDGWKGKT 708



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 48/90 (53%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GY+GRNCE     C+ +  C NGG C +  + + C C + G++G  C  +++EC 
Sbjct: 333 CTCPDGYSGRNCEKAEHACT-SNPCANGGSCHEVPSGFECHCPS-GWSGPTCALDIDECA 390

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
            +    G G C D   GF C C     G+T
Sbjct: 391 SNPCAAG-GTCVDQVDGFECICPEQWVGAT 419



 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ GR C  + ++C+    C NGG CVD VN + C+C A G+ G  C  N++EC+
Sbjct: 775  CICRDGWEGRTCTHNTNDCN-PLPCYNGGICVDGVNWFRCEC-APGFAGPDCRINIDECQ 832

Query: 437  EDRALCGHGV-CYDTYGGFVCACQPATPG 520
                 C +G  C D   G+ C+C P   G
Sbjct: 833  SSP--CAYGATCVDEINGYRCSCPPGRAG 859



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/88 (38%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G++G  C  D+DEC+ +  C  GG CVD V+ + C C    + GA C+ + NECE
Sbjct: 371 CHCPSGWSGPTCALDIDECA-SNPCAAGGTCVDQVDGFECICPEQ-WVGATCQLDANECE 428

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L     C +  GG+ C C P   G
Sbjct: 429 GKPCLNAFS-CKNLIGGYYCDCIPGWKG 455



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ GR+CE + D+C+ ++ C +GG C D  + + C C   G++G  CE +V+ CE
Sbjct: 484 CVCPRGFGGRHCELERDKCA-SSPCHSGGLCEDLADGFHCHC-PQGFSGPLCEVDVDLCE 541

Query: 437 EDRALCGHGV-CYDTYGGFVCAC 502
              + C +G  CY+  G + CAC
Sbjct: 542 P--SPCRNGARCYNLEGDYYCAC 562



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G+ G  C+T+ ++C     C + GRC D VN++ C C   G+ G  C +   +C 
Sbjct: 660 CFCPSGWEGELCDTNPNDCL-PDPCHSRGRCYDLVNDFYCACD-DGWKGKTCHSREFQC- 716

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGST 526
            D   C +G  CYD+   F CAC P   GST
Sbjct: 717 -DAYTCSNGGTCYDSGDTFRCACPPGWKGST 746



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 34/88 (38%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G NC  +V++C G   C +GG C D VN Y C C   G+ G  CE   ++C 
Sbjct: 447 CDCIPGWKGINCHINVNDCRG--QCQHGGTCKDLVNGYQCVC-PRGFGGRHCELERDKCA 503

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D   GF C C     G
Sbjct: 504 SSPCHSG-GLCEDLADGFHCHCPQGFSG 530



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/86 (39%), Positives = 44/86 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   + G +CE++  D CAS+ C  G  C ED    + C CP G+ G  CE++V  
Sbjct: 482 YQCVCPRGFGGRHCELER-DKCASSPCHSGGLC-EDLADGFHCHCPQGFSGPLCEVDVD- 538

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSA 260
             LC   PCRN   C     GD Y A
Sbjct: 539 --LCEPSPCRNGARC-YNLEGDYYCA 561



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 30/88 (34%), Positives = 40/88 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C    +       C+NGG CV +  +++C C   G+ G  C  N N+C 
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC-RDGWEGRTCTHNTNDCN 794

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
                 G G+C D    F C C P   G
Sbjct: 795 PLPCYNG-GICVDGVNWFRCECAPGFAG 821



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           C C   + G  C+ D++ C     C NGG C++A  + Y C C   GY+G  CE   + C
Sbjct: 293 CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC-PDGYSGRNCEKAEHAC 351

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPGST 526
             +    G G C++   GF C C     G T
Sbjct: 352 TSNPCANG-GSCHEVPSGFECHCPSGWSGPT 381



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/80 (40%), Positives = 40/80 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + CHC   ++G  CEVD  D C  + CR+GARC  +  GDY C CP  + G  C   V  
Sbjct: 520 FHCHCPQGFSGPLCEVDV-DLCEPSPCRNGARCY-NLEGDYYCACPDDFGGKNC--SVPR 575

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +P C  G CR    C    G
Sbjct: 576 EP-CPGGACRVIDGCGSDAG 594



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 26/81 (32%), Positives = 36/81 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C+C   + G  C+ D     +   C +G  C+      Y C CP GY G  CE     
Sbjct: 291 WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE---KA 347

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           +  C + PC N GSC   P G
Sbjct: 348 EHACTSNPCANGGSCHEVPSG 368



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/81 (37%), Positives = 41/81 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +ECHC + ++G  C +D  D CAS  C  G  CV+   G + C CP  + G  C+L+ + 
Sbjct: 369 FECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDAN- 425

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
              C   PC N  SC    GG
Sbjct: 426 --ECEGKPCLNAFSCKNLIGG 444



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 22/53 (41%), Positives = 30/53 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  ++DEC  ++ C  G  CVD +N Y C C   G  G RC+
Sbjct: 813 CECAPGFAGPDCRINIDECQ-SSPCAYGATCVDEINGYRCSC-PPGRAGPRCQ 863



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 27/92 (29%), Positives = 38/92 (41%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G+ C +   +C  A  C NGG C D+ + + C C   G+ G+ C    N   
Sbjct: 698 CACDDGWKGKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPP-GWKGSTCAVAKNSSC 755

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
                   G C  +   F C C+    G T T
Sbjct: 756 LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT 787



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C ++  D C S+ C +GA CV++  G Y C CPPG  G  C+  +  
Sbjct: 811 FRCECAPGFAGPDCRINI-DECQSSPCAYGATCVDEING-YRCSCPPGRAGPRCQEVIGF 868

Query: 183 DPLC 194
              C
Sbjct: 869 GRSC 872



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
 Frame = +3

Query: 36  NNCEVDAGD----PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           + C  DAG       AS  C    RCV    G++SC C  G+ GTYC   +  D  C+  
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID-D--CLGQ 643

Query: 204 PCRNNGSC 227
           PCRN G+C
Sbjct: 644 PCRNGGTC 651



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +EC C  ++ G  C++DA + C    C +   C ++  G Y CDC PG+ G  C + V+ 
Sbjct: 407 FECICPEQWVGATCQLDANE-CEGKPCLNAFSC-KNLIGGYYCDCIPGWKGINCHINVN- 463

Query: 183 DPLCVAGPCRNNGSC 227
           D  C  G C++ G+C
Sbjct: 464 D--C-RGQCQHGGTC 475



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 23/75 (30%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + +TG  C  +  D C    CR+G  C+++    + C CP G+ G  C+   + 
Sbjct: 620 FSCICDSGFTGTYCHENIDD-CLGQPCRNGGTCIDEVDA-FRCFCPSGWEGELCDTNPN- 676

Query: 183 DPLCVAGPCRNNGSC 227
           D  C+  PC + G C
Sbjct: 677 D--CLPDPCHSRGRC 689



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 23/75 (30%), Positives = 35/75 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C       C +  C +G  C + G   + C CPPG+ G+ C   V+ 
Sbjct: 696 FYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSG-DTFRCACPPGWKGSTC--AVAK 751

Query: 183 DPLCVAGPCRNNGSC 227
           +  C+  PC N G+C
Sbjct: 752 NSSCLPNPCVNGGTC 766



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 25/87 (28%), Positives = 36/87 (41%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C  +  D C    C +G  CV DG   + C+C PG+ G  C + +  
Sbjct: 773  FSCICRDGWEGRTCTHNTND-CNPLPCYNGGICV-DGVNWFRCECAPGFAGPDCRINID- 829

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC    +C     G   S P
Sbjct: 830  --ECQSSPCAYGATCVDEINGYRCSCP 854



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 24/75 (32%), Positives = 31/75 (41%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G+ C V     C    C +G  CV  G   +SC C  G+ G  C    + 
Sbjct: 734 FRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG-ASFSCICRDGWEGRTCTHNTN- 791

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC N G C
Sbjct: 792 D--CNPLPCYNGGIC 804



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 23/111 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA----------------------CLNGGRCVDAVN-N 367
           C CP  + G+NC    + C G A                       C   GRCV     N
Sbjct: 560 CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGN 619

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           ++C C + G+TG  C  N+++C       G G C D    F C C     G
Sbjct: 620 FSCICDS-GFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWEG 668


>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
          Length = 1999

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 536 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 593

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 594 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 620



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 405 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 463

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 464 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 506



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 460 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 517

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 518 SAPCL-NHADCHDLLNGFQCICLPGFSGT 545



 Score = 77.0 bits (181), Expect = 5e-14
 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G  CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 260 LCLCPPGFIGPGCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 317

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 318 EAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 350



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 676 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 731

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 732 -CHSGPCLNGGSCNPSPGGYYCTCP 755



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 913  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 970

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 971  ---CQSQPCHNHGTCTPKPGGFHCACP 994



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 915  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 972

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 973  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1004



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 676 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 733

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 734 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 760



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 752  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 809

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 810  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 842



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 952  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1009

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1010 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1039



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 714 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 771

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 772 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 803



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 991  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1049

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1050 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1084



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 750 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 805

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 806 RPSCADSPCRNRATCQDSPQGPRCLCP 832



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 338 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 392

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 393 -DMCLSQPCHGDAQCSTNP 410



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 534 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 590

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 591 --ECLSDPCPVGASCLDLPG 608



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 458 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 514

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 515 --ECASAPCLNHADC 527



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 712 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 767

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 768 D-YCVSAPCFNGGTCVNRPG 786



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 94  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 152

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 153 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 187



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 102 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 157

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 158 FCSANPCVNGGVC 170



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 829  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 886

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 887  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 924



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 217 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGC--E 273

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 274 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 298



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 179 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 237

Query: 434 EEDRALCGHGVCY---DTYGGF-VCACQPATPGSTATGC 538
              R     G C    +    F +C C    PG    GC
Sbjct: 238 -PPRGCSNGGTCQLMPEKDSTFHLCLC---PPGFIGPGC 272



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 340 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 395

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 396 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 427



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G  CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 261 CLCPPGFIGPGCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 316

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 317 CEAQGPPHCRNGGTCQNSAG 336



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 378 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 435

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 436 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 469



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 788  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 843

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 844  MDLCAQKPCPRNSHC 858



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 865  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 922

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 923  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 950



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 951  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1007

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1008 --ECLDQPCHPTGTAA 1021



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 417 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 474

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 475 HN---ECLSQPCHPGSTC 489



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 989  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1046

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1047 -DP-CHSQPCFHGGTCEATAG 1065



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 141 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 196

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 197 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 226



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 178 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 235

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 236 -P-CPPRGCSNGGTCQLMPEKDS 256



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 572 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 629

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 630 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 660



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 297 YTCLCPETWTGWDCSEDV-DECEAQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 352

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 353 ENLDD-CIAATCAPGSTC 369



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 376 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 433

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 434 ECLMAQQGPSPCEHGGSCLNTPG 456



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1072 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1130

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1131 KGCGPPSPCLYNGSCSETTG 1150



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1071 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1129

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1130 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1166



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 50  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 107

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 108 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 150



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 648 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 695

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 696 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 726



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 34  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 79



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 647 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 697

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 698 PCAHGGTCYPQPSGYNCTCP 717



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 50  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 107

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 108 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 138


>D86566-1|BAA13116.1|  955|Homo sapiens notch related protein
           protein.
          Length = 955

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCA-QRPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQRPCPRNSHC 859



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 15/40 (37%), Positives = 21/40 (52%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTC 376
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLC 954



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAQLE-DP-CPPSFCSKRGRCHIQASG 139


>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP  YTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTVYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/75 (33%), Positives = 33/75 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP  Y G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTVYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP  YTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTVYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 25/75 (33%), Positives = 33/75 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP  Y G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTVYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2003

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 537 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 594

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 595 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 621



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 464

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 465 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 507



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 318

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 461 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 518

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 519 SAPCL-NHADCHDLLNGFQCICLPGFSGT 546



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 677 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 732

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 733 -CHSGPCLNGGSCNPSPGGYYCTCP 756



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 914  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 971

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 972  ---CQSQPCHNHGTCTPKPGGFHCACP 995



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 916  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 973

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 974  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 143 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 199

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 677 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 734

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 735 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 761



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 753  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 810

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 811  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 953  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1010

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 715 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 772

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 773 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 804



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 992  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1050

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1051 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1085



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 751 YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 806

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            P C   PCRN  +C   P G     P
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCP 833



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 339 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 393

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 394 -DMCLSQPCHGDAQCSTNP 411



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 535 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 591

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 592 --ECLSDPCPVGASCLDLPG 609



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 459 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 515

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 516 --ECASAPCLNHADC 528



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 713 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 768

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 769 D-YCVSAPCFNGGTCVNRPG 787



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 95  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 153

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 154 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 188



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 103 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 158

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 159 FCSANPCVNGGVC 171



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 887

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 218 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 274

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 275 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 299



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 341 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 396

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 428



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 238

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 239 -PPRGCSNGGTC 249



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 262 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 317

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 318 CETQGPPHCRNGGTCQNSAG 337



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 379 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 470



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 789  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 844

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 845  MDLCAQKPCPRNSHC 859



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 866  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 923

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 924  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 951



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 952  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1008

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1009 --ECLDQPCHPTGTAA 1022



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 418 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 475

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 476 HN---ECLSQPCHPGSTC 490



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 990  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1047

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1048 -DP-CHSQPCFHGGTCEATAG 1066



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 142 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 197

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 227



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 179 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 236

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 237 -P-CPPRGCSNGGTCQLMPEKDS 257



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 573 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 630

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 661



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 298 YTCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 353

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 354 ENLDD-CIAATCAPGSTC 370



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 377 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 435 ECLMAQQGPSPCEHGGSCLNTPG 457



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1073 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1132 KGCGPPSPCLYNGSCSETTG 1151



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 51  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 108

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 649 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 696

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 697 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 35  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 80



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 648 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 698

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 699 PCAHGGTCYPQPSGYNCTCP 718



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 51  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 109 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 139


>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
           (Drosophila) protein.
          Length = 2005

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG++G  CE D+DEC  ++ C NGG+C D    + C C   G+ G RC+T V+EC 
Sbjct: 539 CICLPGFSGTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKC-LPGFEGPRCQTEVDECL 596

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            D    G   C D  G F C C     G
Sbjct: 597 SDPCPVG-ASCLDLPGAFFCLCPSGFTG 623



 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 408 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 466

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            GYTG+RCE + NEC       G   C D    F C C P   G
Sbjct: 467 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPPGLEG 509



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G +CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 263 LCLCPPGFIGPDCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 320

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 321 EAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 353



 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPGYTG  CE D +EC  +  C  G  C+D +  + C C   G  G  CE   NEC 
Sbjct: 463 CLCPPGYTGSRCEADHNECL-SQPCHPGSTCLDLLATFHCLC-PPGLEGQLCEVETNECA 520

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
               L  H  C+D   GF C C P   G+
Sbjct: 521 SAPCL-NHADCHDLLNGFQCICLPGFSGT 548



 Score = 76.2 bits (179), Expect = 9e-14
 Identities = 36/85 (42%), Positives = 44/85 (51%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE + G  C SA C HG  C     G Y+C CP GY G  C  E++   
Sbjct: 679 CVCDVGWTGPECEAELGG-CISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEMTA-- 734

Query: 189 LCVAGPCRNNGSCSVPPGGDTYSAP 263
            C +GPC N GSC+  PGG   + P
Sbjct: 735 -CHSGPCLNGGSCNPSPGGYYCTCP 758



 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 916  YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 973

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
               C + PC N+G+C+  PGG   + P
Sbjct: 974  ---CQSQPCHNHGTCTPKPGGFHCACP 997



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 918  CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 975

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
              +    HG C    GGF CAC P   G    G
Sbjct: 976  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 1007



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C PG+TG  C+   D CS A  C+NGG C+       C C   G+ G  CE +VNEC 
Sbjct: 145 CSCMPGWTGEQCQLR-DFCS-ANPCVNGGVCLATYPQIQCHCPP-GFEGHACERDVNECF 201

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPG 520
           +D   C  G  C++T G F C C     G
Sbjct: 202 QDPGPCPKGTSCHNTLGSFQCLCPVGQEG 230



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 33/88 (37%), Positives = 43/88 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG  CE ++  C  +A C +GG C    + Y C C  TGYTG  C   +  C 
Sbjct: 679 CVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTC-PTGYTGPTCSEEMTACH 736

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G G C  + GG+ C C P+  G
Sbjct: 737 SGPCLNG-GSCNPSPGGYYCTCPPSHTG 763



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            CTCPP +TG  C+T  D C  +A C NGG CV+    ++C C A G+ G RCE  +    
Sbjct: 755  CTCPPSHTGPQCQTSTDYCV-SAPCFNGGTCVNRPGTFSCLC-AMGFQGPRCEGKLRPSC 812

Query: 437  EDRALCGHGVCYDTYGGFVCACQPA-TPGSTAT 532
             D        C D+  G  C C    T GS  T
Sbjct: 813  ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 845



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 955  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 1012

Query: 434  -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
             ++     G   C+     F C C P   G
Sbjct: 1013 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 1042



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 33/93 (35%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTCP GYTG  C  ++  C  +  CLNGG C  +   Y C C  + +TG +C+T+ + C 
Sbjct: 717 CTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCV 774

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
                 G G C +  G F C C     G    G
Sbjct: 775 SAPCFNG-GTCVNRPGTFSCLCAMGFQGPRCEG 806



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 994  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 1052

Query: 434  EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                   G G C  T G   GF+C C     G T +
Sbjct: 1053 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 1087



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 33/87 (37%), Positives = 41/87 (47%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   +TG  C+    D C SA C +G  CV +  G +SC C  G+ G  CE +  L
Sbjct: 753  YYCTCPPSHTGPQCQTST-DYCVSAPCFNGGTCV-NRPGTFSCLCAMGFQGPRCEGK--L 808

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             P C   PCRN  +C   P G     P
Sbjct: 809  RPSCADSPCRNRATCQDSPQGPRCLCP 835



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 341 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 395

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 396 -DMCLSQPCHGDAQCSTNP 413



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 29/80 (36%), Positives = 42/80 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   ++G  CE D  D C S+ C +G +C +D  G + C C PG+ G  C+ EV  
Sbjct: 537 FQCICLPGFSGTRCEEDI-DECRSSPCANGGQC-QDQPGAFHCKCLPGFEGPRCQTEVD- 593

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
              C++ PC    SC   PG
Sbjct: 594 --ECLSDPCPVGASCLDLPG 611



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 28/75 (37%), Positives = 38/75 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPPG  G  CE+E + 
Sbjct: 461 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPPGLEGQLCEVETN- 517

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC N+  C
Sbjct: 518 --ECASAPCLNHADC 530



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 97  SPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 155

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 156 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 190



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 31/80 (38%), Positives = 37/80 (46%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG  C  +    C S  C +G  C     G Y C CPP + G  C  + S 
Sbjct: 715 YNCTCPTGYTGPTCSEEM-TACHSGPCLNGGSC-NPSPGGYYCTCPPSHTGPQC--QTST 770

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           D  CV+ PC N G+C   PG
Sbjct: 771 D-YCVSAPCFNGGTCVNRPG 789



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 105 CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 160

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 161 FCSANPCVNGGVC 173



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C CP GYTG +C+T +D C+    C     C+    ++ C C   G+TG  C   ++ C+
Sbjct: 832  CLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLC-LQGWTGPLCNLPLSSCQ 889

Query: 437  --------EDRALCGH-GVCYDTYGGFVCACQPATPGS 523
                    +  +LC + G+C D+   + C C P   GS
Sbjct: 890  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 927



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 220 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC--E 276

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 277 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 301



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 343 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 398

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 399 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 430



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 182 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 240

Query: 434 EEDRALCGHGVC 469
              R     G C
Sbjct: 241 -PPRGCSNGGTC 251



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 264 CLCPPGFIGPDCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 319

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 320 CEAQGPPHCRNGGTCQNSAG 339



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 381 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 438

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 439 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 472



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 26/75 (34%), Positives = 34/75 (45%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  CE      CA + CR+ A C +  +G   C CP GY G  C+   +L
Sbjct: 791  FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQ---TL 846

Query: 183  DPLCVAGPCRNNGSC 227
              LC   PC  N  C
Sbjct: 847  MDLCAQKPCPRNSHC 861



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA----------CRHGARCVEDGRGDYSCDCPPGYH 152
            + C C   +TG  C +     C  AA          C +G  CV+ G   Y C CPPG+ 
Sbjct: 868  FHCLCLQGWTGPLCNLPLSS-CQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPGFQ 925

Query: 153  GTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 926  GSLCQDHV--NP-CESRPCQNGATCMAQPSG 953



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 954  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 1010

Query: 183  DPLCVAGPCRNNGSCS 230
               C+  PC   G+ +
Sbjct: 1011 --ECLDQPCHPTGTAA 1024



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 420 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 477

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 478 HN---ECLSQPCHPGSTC 492



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 992  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 1049

Query: 180  LDPLCVAGPCRNNGSCSVPPG 242
             DP C + PC + G+C    G
Sbjct: 1050 -DP-CHSQPCFHGGTCEATAG 1068



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 144 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 199

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 200 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 229



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 181 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 238

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 239 -P-CPPRGCSNGGTCQLMPEKDS 259



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C+ +  D C S  C  GA C+ D  G + C CP G+ G  CE+ +  
Sbjct: 575 FHCKCLPGFEGPRCQTEV-DECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCA 632

Query: 183 DPLC----VAGPCRNNGSCSVPPGGDTYSAP 263
             LC    +    ++  +C  P G    + P
Sbjct: 633 PNLCQPKQICKDQKDKANCLCPDGSPGCAPP 663



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 300 YTCLCPETWTGWDCSEDV-DECEAQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 355

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 356 ENLDD-CIAATCAPGSTC 372



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 379 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 436

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 437 ECLMAQQGPSPCEHGGSCLNTPG 459



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
            CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 1075 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1133

Query: 183  DPLCVAGPCRNNGSCSVPPG 242
                   PC  NGSCS   G
Sbjct: 1134 KGCGPPSPCLYNGSCSETTG 1153



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
            +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 1074 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1132

Query: 422  VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
               C        +G C +T G    GF C+C  ++PG
Sbjct: 1133 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1169



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 53  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 110

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 111 FTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 153



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CP G  G  C    D C+    C + G C       +C C   G+TG  CE  +  C 
Sbjct: 651 CLCPDGSPG--CAPPEDNCT----C-HHGHC----QRSSCVCDV-GWTGPECEAELGGCI 698

Query: 437 EDRALCGHG-VCYDTYGGFVCACQPATPGSTAT 532
              A C HG  CY    G+ C C     G T +
Sbjct: 699 S--APCAHGGTCYPQPSGYNCTCPTGYTGPTCS 729



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 37  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 82



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +3

Query: 39  NCEVDAGDP-CA----SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
           NC    G P CA    +  C HG  C        SC C  G+ G  CE E+     C++ 
Sbjct: 650 NCLCPDGSPGCAPPEDNCTCHHG-HCQRS-----SCVCDVGWTGPECEAELG---GCISA 700

Query: 204 PCRNNGSCSVPPGGDTYSAP 263
           PC + G+C   P G   + P
Sbjct: 701 PCAHGGTCYPQPSGYNCTCP 720



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 53  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 110

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 111 FTGERCQAQLE-DP-CPPSFCSKRGRCHIQASG 141


>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
            protein.
          Length = 1529

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G NCE +VD+C     C N   CVD +NNYTC C    YTG  CE  ++ C 
Sbjct: 984  CICADGFEGENCEVNVDDCED-NDCENNSTCVDGINNYTCLCPPE-YTGELCEEKLDFCA 1041

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
            +D   C H   C  T  GF C C P   G
Sbjct: 1042 QDLNPCQHDSKCILTPKGFKCDCTPGYVG 1070



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPP YTG  CE  +D C+     C +  +C+     + CDCT  GY G  C+ + ++C
Sbjct: 1022 CLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTP-GYVGEHCDIDFDDC 1080

Query: 434  EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            ++++  C +G  C D   G+ C C     G
Sbjct: 1081 QDNK--CKNGAHCTDAVNGYTCICPEGYSG 1108



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C C PGY G +C+ D D+C     C NG  C DAVN YTC C   GY+G  CE
Sbjct: 1062 CDCTPGYVGEHCDIDFDDCQD-NKCKNGAHCTDAVNGYTCIC-PEGYSGLFCE 1112



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTCP G+ G++C+  +  C  +  C +GG C       + + C C A G+ G  CE NV+
Sbjct: 943  CTCPYGFKGQDCDVPIHACI-SNPCKHGGTCHLKEGEEDGFWCIC-ADGFEGENCEVNVD 1000

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    + C C P   G
Sbjct: 1001 DC-EDNDCENNSTCVDGINNYTCLCPPEYTG 1030



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 27/71 (38%), Positives = 38/71 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C CT  Y G +C++D  D C    C++GA C +   G Y+C CP GY G +CE    +
Sbjct: 1060 FKCDCTPGYVGEHCDIDFDD-CQDNKCKNGAHCTDAVNG-YTCICPEGYSGLFCEFSPPM 1117

Query: 183  DPLCVAGPCRN 215
              L    PC N
Sbjct: 1118 -VLPRTSPCDN 1127



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 28/79 (35%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G NCEV+  D C    C + + CV DG  +Y+C CPP Y G  CE ++    
Sbjct: 984  CICADGFEGENCEVNVDD-CEDNDCENNSTCV-DGINNYTCLCPPEYTGELCEEKLDFCA 1041

Query: 189  LCVAGPCRNNGSCSVPPGG 245
              +  PC+++  C + P G
Sbjct: 1042 QDL-NPCQHDSKCILTPKG 1059



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  CE +  D CA     C+H ++C+   +G + CDC PGY G +C+++ 
Sbjct: 1020 YTCLCPPEYTGELCE-EKLDFCAQDLNPCQHDSKCILTPKG-FKCDCTPGYVGEHCDIDF 1077

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              D  C    C+N   C+    G T   P
Sbjct: 1078 D-D--CQDNKCKNGAHCTDAVNGYTCICP 1103



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/84 (32%), Positives = 36/84 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C+    DPC    C HG  C+      YSC C  G+ G  C+ E  L
Sbjct: 1354 FTCECQEGWMGPLCDQRTNDPCLGNKCVHGT-CLPINAFSYSCKCLEGHGGVLCDEEEDL 1412

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTY 254
               C A  C+ +G C +   G  Y
Sbjct: 1413 FNPCQAIKCK-HGKCRLSGLGQPY 1435



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   + G +C+V     C S  C+HG  C +++G  D + C C  G+ G  CE+ V
Sbjct: 941  YRCTCPYGFKGQDCDVPI-HACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNV 999

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 1000 D-D--CEDNDCENNSTC 1013



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            +PC S  C++   C  D    Y C CP G+ G  C++ +     C++ PC++ G+C +  
Sbjct: 920  NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIH---ACISNPCKHGGTCHLKE 976

Query: 240  G 242
            G
Sbjct: 977  G 977



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNC--EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  C  E D  +PC +  C+HG +C   G G   C+C  GY G  C+ E+
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHG-KCRLSGLGQPYCECSSGYTGDSCDREI 1451

Query: 177  S 179
            S
Sbjct: 1452 S 1452



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   Y+G  CE      +    PC +  C++GA+C+     +  C C PGY G  C
Sbjct: 1098 YTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR-INEPICQCLPGYQGEKC 1156

Query: 165  ELEVSLD 185
            E  VS++
Sbjct: 1157 EKLVSVN 1163



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD-------VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C CP GY+G  CE            C     C NG +C+  +N   C C   GY G +CE
Sbjct: 1100 CICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCIVRINEPICQC-LPGYQGEKCE 1157

Query: 416  TNVN 427
              V+
Sbjct: 1158 KLVS 1161


>BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophila)
           protein.
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 388 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 445

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 446 --RNPCAHGGTCHDLENGLMCTCPAGFSG 472



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 362

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 363 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 397



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 308 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 364

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 365 S--CADSPCFNGGSCRERNQGANYA 387



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 328

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 329 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 356



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 386 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 442

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 443 D--CARNPCAHGGTC 455



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 326

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 327 --ECDSNPCRNGGSC 339



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 418 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 472

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 515



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 426 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 483

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 484 -CASSPCFNRATCYTDLSTDTF 504



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 346 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 404

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 405 ---RCTSNPCANGGQC 417



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 464 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523

Query: 183 DP 188
            P
Sbjct: 524 PP 525



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 462 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 518



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 239 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 289

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 290 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 318



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 171 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 218

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 219 -QPICLSGCHEQNGYCSKP 236


>AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 388 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 445

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 446 --RNPCAHGGTCHDLENGLMCTCPAGFSG 472



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 362

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 363 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 397



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 308 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 364

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 365 S--CADSPCFNGGSCRERNQGANYA 387



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 328

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 329 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 356



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 386 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 442

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 443 D--CARNPCAHGGTC 455



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 326

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 327 --ECDSNPCRNGGSC 339



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 418 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 472

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 515



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 426 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 483

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 484 -CASSPCFNRATCYTDLSTDTF 504



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 346 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 404

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 405 ---RCTSNPCANGGQC 417



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 464 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523

Query: 183 DP 188
            P
Sbjct: 524 PP 525



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 462 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 518



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 239 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 289

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 290 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 318



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 171 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 218

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 219 -QPICLSGCHEQNGYCSKP 236


>AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.
          Length = 653

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 356 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 413

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 414 --RNPCAHGGTCHDLENGLMCTCPAGFSG 440



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 273 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 330

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 331 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 365



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 276 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 332

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 333 S--CADSPCFNGGSCRERNQGANYA 355



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 238 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 296

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 297 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 324



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 354 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 410

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 411 D--CARNPCAHGGTC 423



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 236 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 294

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 295 --ECDSNPCRNGGSC 307



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 386 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 440

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 441 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 483



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 394 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 451

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 452 -CASSPCFNRATCYTDLSTDTF 472



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 314 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 372

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 373 ---RCTSNPCANGGQC 385



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 432 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 491

Query: 183 DP 188
            P
Sbjct: 492 PP 493



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 430 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 486



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 207 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 257

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 258 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 286



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 139 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 186

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 187 -QPICLSGCHEQNGYCSKP 204


>AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 388 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 445

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 446 --RNPCAHGGTCHDLENGLMCTCPAGFSG 472



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 362

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 363 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 397



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 308 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 364

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 365 S--CADSPCFNGGSCRERNQGANYA 387



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 328

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 329 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 356



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 386 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 442

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 443 D--CARNPCAHGGTC 455



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 326

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 327 --ECDSNPCRNGGSC 339



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 418 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 472

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 515



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 426 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 483

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 484 -CASSPCFNRATCYTDLSTDTF 504



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 346 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 404

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 405 ---RCTSNPCANGGQC 417



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 464 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523

Query: 183 DP 188
            P
Sbjct: 524 PP 525



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 462 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 518



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 239 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 289

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 290 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 318



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 171 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 218

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 219 -QPICLSGCHEQNGYCSKP 236


>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
          Length = 1525

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G NCE +VD+C     C N   CVD +NNYTC C    YTG  CE  ++ C 
Sbjct: 980  CICADGFEGENCEVNVDDCED-NDCENNSTCVDGINNYTCLCPPE-YTGELCEEKLDFCA 1037

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
            +D   C H   C  T  GF C C P   G
Sbjct: 1038 QDLNPCQHDSKCILTPKGFKCDCTPGYVG 1066



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPP YTG  CE  +D C+     C +  +C+     + CDCT  GY G  C+ + ++C
Sbjct: 1018 CLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTP-GYVGEHCDIDFDDC 1076

Query: 434  EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            ++++  C +G  C D   G+ C C     G
Sbjct: 1077 QDNK--CKNGAHCTDAVNGYTCICPEGYSG 1104



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C C PGY G +C+ D D+C     C NG  C DAVN YTC C   GY+G  CE
Sbjct: 1058 CDCTPGYVGEHCDIDFDDCQD-NKCKNGAHCTDAVNGYTCIC-PEGYSGLFCE 1108



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTCP G+ G++C+  +  C  +  C +GG C       + + C C A G+ G  CE NV+
Sbjct: 939  CTCPYGFKGQDCDVPIHACI-SNPCKHGGTCHLKEGEEDGFWCIC-ADGFEGENCEVNVD 996

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    + C C P   G
Sbjct: 997  DC-EDNDCENNSTCVDGINNYTCLCPPEYTG 1026



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 27/71 (38%), Positives = 38/71 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C CT  Y G +C++D  D C    C++GA C +   G Y+C CP GY G +CE    +
Sbjct: 1056 FKCDCTPGYVGEHCDIDFDD-CQDNKCKNGAHCTDAVNG-YTCICPEGYSGLFCEFSPPM 1113

Query: 183  DPLCVAGPCRN 215
              L    PC N
Sbjct: 1114 -VLPRTSPCDN 1123



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 28/79 (35%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G NCEV+  D C    C + + CV DG  +Y+C CPP Y G  CE ++    
Sbjct: 980  CICADGFEGENCEVNVDD-CEDNDCENNSTCV-DGINNYTCLCPPEYTGELCEEKLDFCA 1037

Query: 189  LCVAGPCRNNGSCSVPPGG 245
              +  PC+++  C + P G
Sbjct: 1038 QDL-NPCQHDSKCILTPKG 1055



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  CE +  D CA     C+H ++C+   +G + CDC PGY G +C+++ 
Sbjct: 1016 YTCLCPPEYTGELCE-EKLDFCAQDLNPCQHDSKCILTPKG-FKCDCTPGYVGEHCDIDF 1073

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              D  C    C+N   C+    G T   P
Sbjct: 1074 D-D--CQDNKCKNGAHCTDAVNGYTCICP 1099



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/84 (32%), Positives = 36/84 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C+    DPC    C HG  C+      YSC C  G+ G  C+ E  L
Sbjct: 1350 FTCECQEGWMGPLCDQRTNDPCLGNKCVHGT-CLPINAFSYSCKCLEGHGGVLCDEEEDL 1408

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTY 254
               C A  C+ +G C +   G  Y
Sbjct: 1409 FNPCQAIKCK-HGKCRLSGLGQPY 1431



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   + G +C+V     C S  C+HG  C +++G  D + C C  G+ G  CE+ V
Sbjct: 937  YRCTCPYGFKGQDCDVPI-HACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNV 995

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 996  D-D--CEDNDCENNSTC 1009



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            +PC S  C++   C  D    Y C CP G+ G  C++ +     C++ PC++ G+C +  
Sbjct: 916  NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIH---ACISNPCKHGGTCHLKE 972

Query: 240  G 242
            G
Sbjct: 973  G 973



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNC--EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  C  E D  +PC +  C+HG +C   G G   C+C  GY G  C+ E+
Sbjct: 1389 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHG-KCRLSGLGQPYCECSSGYTGDSCDREI 1447

Query: 177  S 179
            S
Sbjct: 1448 S 1448



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   Y+G  CE      +    PC +  C++GA+C+     +  C C PGY G  C
Sbjct: 1094 YTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR-INEPICQCLPGYQGEKC 1152

Query: 165  ELEVSLD 185
            E  VS++
Sbjct: 1153 EKLVSVN 1159



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD-------VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C CP GY+G  CE            C     C NG +C+  +N   C C   GY G +CE
Sbjct: 1096 CICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCIVRINEPICQC-LPGYQGEKCE 1153

Query: 416  TNVN 427
              V+
Sbjct: 1154 KLVS 1157


>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
            slit protein Slit2 protein.
          Length = 1521

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G NCE +VD+C     C N   CVD +NNYTC C    YTG  CE  ++ C 
Sbjct: 976  CICADGFEGENCEVNVDDCED-NDCENNSTCVDGINNYTCLCPPE-YTGELCEEKLDFCA 1033

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
            +D   C H   C  T  GF C C P   G
Sbjct: 1034 QDLNPCQHDSKCILTPKGFKCDCTPGYVG 1062



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPP YTG  CE  +D C+     C +  +C+     + CDCT  GY G  C+ + ++C
Sbjct: 1014 CLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTP-GYVGEHCDIDFDDC 1072

Query: 434  EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            ++++  C +G  C D   G+ C C     G
Sbjct: 1073 QDNK--CKNGAHCTDAVNGYTCICPEGYSG 1100



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C C PGY G +C+ D D+C     C NG  C DAVN YTC C   GY+G  CE
Sbjct: 1054 CDCTPGYVGEHCDIDFDDCQD-NKCKNGAHCTDAVNGYTCIC-PEGYSGLFCE 1104



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTCP G+ G++C+  +  C  +  C +GG C       + + C C A G+ G  CE NV+
Sbjct: 935  CTCPYGFKGQDCDVPIHACI-SNPCKHGGTCHLKEGEEDGFWCIC-ADGFEGENCEVNVD 992

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    + C C P   G
Sbjct: 993  DC-EDNDCENNSTCVDGINNYTCLCPPEYTG 1022



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 27/71 (38%), Positives = 38/71 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C CT  Y G +C++D  D C    C++GA C +   G Y+C CP GY G +CE    +
Sbjct: 1052 FKCDCTPGYVGEHCDIDFDD-CQDNKCKNGAHCTDAVNG-YTCICPEGYSGLFCEFSPPM 1109

Query: 183  DPLCVAGPCRN 215
              L    PC N
Sbjct: 1110 -VLPRTSPCDN 1119



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 28/79 (35%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G NCEV+  D C    C + + CV DG  +Y+C CPP Y G  CE ++    
Sbjct: 976  CICADGFEGENCEVNVDD-CEDNDCENNSTCV-DGINNYTCLCPPEYTGELCEEKLDFCA 1033

Query: 189  LCVAGPCRNNGSCSVPPGG 245
              +  PC+++  C + P G
Sbjct: 1034 QDL-NPCQHDSKCILTPKG 1051



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  CE +  D CA     C+H ++C+   +G + CDC PGY G +C+++ 
Sbjct: 1012 YTCLCPPEYTGELCE-EKLDFCAQDLNPCQHDSKCILTPKG-FKCDCTPGYVGEHCDIDF 1069

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              D  C    C+N   C+    G T   P
Sbjct: 1070 D-D--CQDNKCKNGAHCTDAVNGYTCICP 1095



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/84 (32%), Positives = 36/84 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C+    DPC    C HG  C+      YSC C  G+ G  C+ E  L
Sbjct: 1346 FTCECQEGWMGPLCDQRTNDPCLGNKCVHGT-CLPINAFSYSCKCLEGHGGVLCDEEEDL 1404

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTY 254
               C A  C+ +G C +   G  Y
Sbjct: 1405 FNPCQAIKCK-HGKCRLSGLGQPY 1427



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   + G +C+V     C S  C+HG  C +++G  D + C C  G+ G  CE+ V
Sbjct: 933  YRCTCPYGFKGQDCDVPI-HACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNV 991

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 992  D-D--CEDNDCENNSTC 1005



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            +PC S  C++   C  D    Y C CP G+ G  C++ +     C++ PC++ G+C +  
Sbjct: 912  NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIH---ACISNPCKHGGTCHLKE 968

Query: 240  G 242
            G
Sbjct: 969  G 969



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNC--EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  C  E D  +PC +  C+HG +C   G G   C+C  GY G  C+ E+
Sbjct: 1385 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHG-KCRLSGLGQPYCECSSGYTGDSCDREI 1443

Query: 177  S 179
            S
Sbjct: 1444 S 1444



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   Y+G  CE      +    PC +  C++GA+C+     +  C C PGY G  C
Sbjct: 1090 YTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR-INEPICQCLPGYQGEKC 1148

Query: 165  ELEVSLD 185
            E  VS++
Sbjct: 1149 EKLVSVN 1155



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD-------VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C CP GY+G  CE            C     C NG +C+  +N   C C   GY G +CE
Sbjct: 1092 CICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCIVRINEPICQC-LPGYQGEKCE 1149

Query: 416  TNVN 427
              V+
Sbjct: 1150 KLVS 1153


>AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 388 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 445

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 446 --RNPCAHGGTCHDLENGLMCTCPAGFSG 472



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 362

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 363 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 397



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 308 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 364

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 365 S--CADSPCFNGGSCRERNQGANYA 387



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 328

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 329 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 356



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 386 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 442

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 443 D--CARNPCAHGGTC 455



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 326

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 327 --ECDSNPCRNGGSC 339



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 418 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 472

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 515



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 426 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 483

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 484 -CASSPCFNRATCYTDLSTDTF 504



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 346 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 404

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 405 ---RCTSNPCANGGQC 417



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 464 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523

Query: 183 DP 188
            P
Sbjct: 524 PP 525



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 462 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 518



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 239 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 289

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 290 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 318



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 171 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 218

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 219 -QPICLSGCHEQNGYCSKP 236


>AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2
           protein.
          Length = 685

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPP +TG NCE  VD C+ +  C NGG+C++   +  C C   G+TG  CE +V++C 
Sbjct: 388 CECPPNFTGSNCEKKVDRCT-SNPCANGGQCLNRGPSRMCRC-RPGFTGTYCELHVSDCA 445

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             R  C H G C+D   G +C C     G
Sbjct: 446 --RNPCAHGGTCHDLENGLMCTCPAGFSG 472



 Score = 72.1 bits (169), Expect = 1e-12
 Identities = 37/96 (38%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
 Frame = +2

Query: 242 RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           +R   CTC PGYTG +CE ++ EC  +  C NGG C D  + Y C C   GY G  CE +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECD-SNPCRNGGSCKDQEDGYHCLC-PPGYYGLHCEHS 362

Query: 422 VNECEEDRALCGHGVCYDTYGG--FVCACQPATPGS 523
              C +     G G C +   G  + C C P   GS
Sbjct: 363 TLSCADSPCFNG-GSCRERNQGANYACECPPNFTGS 397



 Score = 71.3 bits (167), Expect = 3e-12
 Identities = 35/85 (41%), Positives = 45/85 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG +CE++  + C S  CR+G  C +D    Y C CPPGY+G +CE   +L
Sbjct: 308 YTCTCRPGYTGVDCELELSE-CDSNPCRNGGSC-KDQEDGYHCLCPPGYYGLHCE-HSTL 364

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYS 257
              C   PC N GSC     G  Y+
Sbjct: 365 S--CADSPCFNGGSCRERNQGANYA 387



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-VNNYTCDCTATGYTGARCETNVNEC 433
           CTC  G+ G  C+ D++ C+  + C NG  C ++   +YTC C   GYTG  CE  ++EC
Sbjct: 270 CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRP-GYTGVDCELELSEC 328

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
           + +    G G C D   G+ C C P   G
Sbjct: 329 DSNPCRNG-GSCKDQEDGYHCLCPPGYYG 356



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 33/75 (44%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   +TG+NCE    D C S  C +G +C+  G     C C PG+ GTYCEL VS 
Sbjct: 386 YACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRM-CRCRPGFTGTYCELHVS- 442

Query: 183 DPLCVAGPCRNNGSC 227
           D  C   PC + G+C
Sbjct: 443 D--CARNPCAHGGTC 455



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 41/75 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C   + G  C+ D       + C++GA C   G+  Y+C C PGY G  CELE+S 
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS- 326

Query: 183 DPLCVAGPCRNNGSC 227
              C + PCRN GSC
Sbjct: 327 --ECDSNPCRNGGSC 339



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 6/106 (5%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG 403
           L R P R   +C C PG+TG  CE  V +C+    C +GG C D  N   C C A G++G
Sbjct: 418 LNRGPSR---MCRCRPGFTGTYCELHVSDCA-RNPCAHGGTCHDLENGLMCTCPA-GFSG 472

Query: 404 ARCE--TNVNECEE----DRALCGHGVCYDTYGGFVCACQPATPGS 523
            RCE  T+++ C      +RA C   +  DT   FVC C     GS
Sbjct: 473 RRCEVRTSIDACASSPCFNRATCYTDLSTDT---FVCNCPYGFVGS 515



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/82 (36%), Positives = 38/82 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  CE+   D CA   C HG  C  D      C CP G+ G  CE+  S+D 
Sbjct: 426 CRCRPGFTGTYCELHVSD-CARNPCAHGGTC-HDLENGLMCTCPAGFSGRRCEVRTSIDA 483

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C + PC N  +C      DT+
Sbjct: 484 -CASSPCFNRATCYTDLSTDTF 504



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 29/76 (38%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVS 179
           Y C C   Y G +CE      CA + C +G  C E  +G +Y+C+CPP + G+ CE +V 
Sbjct: 346 YHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVD 404

Query: 180 LDPLCVAGPCRNNGSC 227
               C + PC N G C
Sbjct: 405 ---RCTSNPCANGGQC 417



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAG-DPCASAACRHGARCVEDGRGD-YSCDCPPGYHGTYCELEVSL 182
           C C A ++G  CEV    D CAS+ C + A C  D   D + C+CP G+ G+ CE  V L
Sbjct: 464 CTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523

Query: 183 DP 188
            P
Sbjct: 524 PP 525



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCE--TDVDECSGAAACLNGGRCVD--AVNNYTCDCTATGYTGARCE 415
           L+CTCP G++GR CE  T +D C+ ++ C N   C    + + + C+C   G+ G+RCE
Sbjct: 462 LMCTCPAGFSGRRCEVRTSIDACA-SSPCFNRATCYTDLSTDTFVCNC-PYGFVGSRCE 518



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ GR C    +EC     C +G         + C C   G+ G  C+ ++N C 
Sbjct: 239 CLCRPGWQGRLC----NECIPHNGCRHG----TCSTPWQCTCD-EGWGGLFCDQDLNYCT 289

Query: 437 EDRALCGHGVCYDTYG--GFVCACQPATPG 520
              + C +G      G   + C C+P   G
Sbjct: 290 H-HSPCKNGATCSNSGQRSYTCTCRPGYTG 318



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGAR-CVEDGRGDYSCDCPPGYHGTYCELEVS 179
           Y   C+  Y G+NC       C       G   C  DG    +  C PG+ G YC+    
Sbjct: 171 YRVICSDNYYGDNCS----RLCKKRNDHFGHYVCQPDG----NLSCLPGWTGEYCQ---- 218

Query: 180 LDPLCVAGPCRNNGSCSVP 236
             P+C++G    NG CS P
Sbjct: 219 -QPICLSGCHEQNGYCSKP 236


>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
          Length = 1529

 Score = 79.8 bits (188), Expect = 7e-15
 Identities = 38/89 (42%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C  G+ G NCE +VD+C     C N   CVD +NNYTC C    YTG  CE  ++ C 
Sbjct: 984  CICADGFEGENCEVNVDDCED-NDCENNSTCVDGINNYTCLCPPE-YTGELCEEKLDFCA 1041

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
            +D   C H   C  T  GF C C P   G
Sbjct: 1042 QDLNPCQHDSKCILTPKGFKCDCTPGYVG 1070



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            C CPP YTG  CE  +D C+     C +  +C+     + CDCT  GY G  C+ + ++C
Sbjct: 1022 CLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTP-GYVGEHCDIDFDDC 1080

Query: 434  EEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            ++++  C +G  C D   G+ C C     G
Sbjct: 1081 QDNK--CKNGAHCTDAVNGYTCICPEGYSG 1108



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 27/53 (50%), Positives = 31/53 (58%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C C PGY G +C+ D D+C     C NG  C DAVN YTC C   GY+G  CE
Sbjct: 1062 CDCTPGYVGEHCDIDFDDCQD-NKCKNGAHCTDAVNGYTCIC-PEGYSGLFCE 1112



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTCP G+ G++C+  +  C  +  C +GG C       + + C C A G+ G  CE NV+
Sbjct: 943  CTCPYGFKGQDCDVPIHACI-SNPCKHGGTCHLKEGEEDGFWCIC-ADGFEGENCEVNVD 1000

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    + C C P   G
Sbjct: 1001 DC-EDNDCENNSTCVDGINNYTCLCPPEYTG 1030



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 27/71 (38%), Positives = 38/71 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            ++C CT  Y G +C++D  D C    C++GA C +   G Y+C CP GY G +CE    +
Sbjct: 1060 FKCDCTPGYVGEHCDIDFDD-CQDNKCKNGAHCTDAVNG-YTCICPEGYSGLFCEFSPPM 1117

Query: 183  DPLCVAGPCRN 215
              L    PC N
Sbjct: 1118 -VLPRTSPCDN 1127



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 28/79 (35%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   + G NCEV+  D C    C + + CV DG  +Y+C CPP Y G  CE ++    
Sbjct: 984  CICADGFEGENCEVNVDD-CEDNDCENNSTCV-DGINNYTCLCPPEYTGELCEEKLDFCA 1041

Query: 189  LCVAGPCRNNGSCSVPPGG 245
              +  PC+++  C + P G
Sbjct: 1042 QDL-NPCQHDSKCILTPKG 1059



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  CE +  D CA     C+H ++C+   +G + CDC PGY G +C+++ 
Sbjct: 1020 YTCLCPPEYTGELCE-EKLDFCAQDLNPCQHDSKCILTPKG-FKCDCTPGYVGEHCDIDF 1077

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              D  C    C+N   C+    G T   P
Sbjct: 1078 D-D--CQDNKCKNGAHCTDAVNGYTCICP 1103



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/84 (32%), Positives = 36/84 (42%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C+    DPC    C HG  C+      YSC C  G+ G  C+ E  L
Sbjct: 1354 FTCECQEGWMGPLCDQRTNDPCLGNKCVHGT-CLPINAFSYSCKCLEGHGGVLCDEEEDL 1412

Query: 183  DPLCVAGPCRNNGSCSVPPGGDTY 254
               C A  C+ +G C +   G  Y
Sbjct: 1413 FNPCQAIKCK-HGKCRLSGLGQPY 1435



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   + G +C+V     C S  C+HG  C +++G  D + C C  G+ G  CE+ V
Sbjct: 941  YRCTCPYGFKGQDCDVPI-HACISNPCKHGGTCHLKEGEEDGFWCICADGFEGENCEVNV 999

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 1000 D-D--CEDNDCENNSTC 1013



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 19/61 (31%), Positives = 32/61 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            +PC S  C++   C  D    Y C CP G+ G  C++ +     C++ PC++ G+C +  
Sbjct: 920  NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIH---ACISNPCKHGGTCHLKE 976

Query: 240  G 242
            G
Sbjct: 977  G 977



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNC--EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   + G  C  E D  +PC +  C+HG +C   G G   C+C  GY G  C+ E+
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHG-KCRLSGLGQPYCECSSGYTGDSCDREI 1451

Query: 177  S 179
            S
Sbjct: 1452 S 1452



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   Y+G  CE      +    PC +  C++GA+C+     +  C C PGY G  C
Sbjct: 1098 YTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVR-INEPICQCLPGYQGEKC 1156

Query: 165  ELEVSLD 185
            E  VS++
Sbjct: 1157 EKLVSVN 1163



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD-------VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            C CP GY+G  CE            C     C NG +C+  +N   C C   GY G +CE
Sbjct: 1100 CICPEGYSGLFCEFSPPMVLPRTSPCDNFD-CQNGAQCIVRINEPICQC-LPGYQGEKCE 1157

Query: 416  TNVN 427
              V+
Sbjct: 1158 KLVS 1161


>AL450324-2|CAI13283.1|  186|Homo sapiens protein ( Human DNA
           sequence from clone RP11-307F22 on chromosome 6. ).
          Length = 186

 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 36/88 (40%), Positives = 52/88 (59%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCG 457
           TG NCE ++DEC  +  CL+ G C+D +N+YTCDC  +G+ G  CETN N+C  +   C 
Sbjct: 37  TGINCEINLDECL-SEPCLHDGVCIDGINHYTCDC-KSGFFGTHCETNANDCLSNP--CL 92

Query: 458 HGVCYDTYGGFVCACQPATPGSTATGCR 541
           HG C +    + C+C       T+T C+
Sbjct: 93  HGRCTELINEYPCSCD---ADGTSTQCK 117



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 31/92 (33%), Positives = 47/92 (51%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C  G+ G +CET+ ++C  +  CL+ GRC + +N Y C C A G T  +C+  +N
Sbjct: 65  HYTCDCKSGFFGTHCETNANDCL-SNPCLH-GRCTELINEYPCSCDADG-TSTQCKIKIN 121

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           +C     +   G C  +  GF C C     G+
Sbjct: 122 DCTSIPCM-NEGFCQKSAHGFTCICPRGYTGA 152



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 28/67 (41%), Positives = 39/67 (58%)
 Frame = +3

Query: 30  TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPC 209
           TG NCE++  D C S  C H   C+ DG   Y+CDC  G+ GT+CE   + D  C++ PC
Sbjct: 37  TGINCEINL-DECLSEPCLHDGVCI-DGINHYTCDCKSGFFGTHCETNAN-D--CLSNPC 91

Query: 210 RNNGSCS 230
             +G C+
Sbjct: 92  L-HGRCT 97



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/87 (35%), Positives = 42/87 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C + + G +CE +A D C S  C HG RC E    +Y C C      T C+++++ 
Sbjct: 66  YTCDCKSGFFGTHCETNAND-CLSNPCLHG-RCTE-LINEYPCSCDADGTSTQCKIKIN- 121

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
           D  C + PC N G C     G T   P
Sbjct: 122 D--CTSIPCMNEGFCQKSAHGFTCICP 146



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C    T   C+  +++C+ +  C+N G C  + + +TC C   GYTGA CE +++ C 
Sbjct: 105 CSCDADGTSTQCKIKINDCT-SIPCMNEGFCQKSAHGFTCICPR-GYTGAYCEKSIDNCA 162

Query: 437 E---DRALC-GHGVCYDTYG 484
           E   +  +C   G+C D  G
Sbjct: 163 EPELNSVICLNGGICVDGPG 182



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS- 179
           Y C C A  T   C++   D C S  C +   C +   G ++C CP GY G YCE  +  
Sbjct: 103 YPCSCDADGTSTQCKIKIND-CTSIPCMNEGFCQKSAHG-FTCICPRGYTGAYCEKSIDN 160

Query: 180 -LDPLCVAGPCRNNGSCSVPPG 242
             +P   +  C N G C   PG
Sbjct: 161 CAEPELNSVICLNGGICVDGPG 182



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 15/42 (35%), Positives = 20/42 (47%)
 Frame = +2

Query: 380 CTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
           C     TG  CE N++EC  +  L   GVC D    + C C+
Sbjct: 31  CLVCSNTGINCEINLDECLSEPCL-HDGVCIDGINHYTCDCK 71


>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
            protein protein.
          Length = 3222

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 36/95 (37%), Positives = 49/95 (51%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            LC C PGY G  CE D+DEC   + C +GG C + V  ++C C   G+TG  CE ++NEC
Sbjct: 2145 LCKCLPGYAGSWCEIDIDECL-PSPCHSGGTCHNLVGGFSCSC-PDGFTGRACERDINEC 2202

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
             +     G  +C +  G F C C+    G     C
Sbjct: 2203 LQSPCKNG-AICQNFPGSFNCVCKTGYTGVFGKHC 2236



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 28/78 (35%), Positives = 39/78 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   Y G+ CE+D  D C  + C  G  C  +  G +SC CP G+ G  CE +++   
Sbjct: 2146 CKCLPGYAGSWCEIDI-DECLPSPCHSGGTC-HNLVGGFSCSCPDGFTGRACERDIN--- 2200

Query: 189  LCVAGPCRNNGSCSVPPG 242
             C+  PC+N   C   PG
Sbjct: 2201 ECLQSPCKNGAICQNFPG 2218



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 28/64 (43%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVN 427
            C+CP G+TGR CE D++EC   + C NG  C +   ++ C C  TGYTG     CE N  
Sbjct: 2184 CSCPDGFTGRACERDINECL-QSPCKNGAICQNFPGSFNCVC-KTGYTGVFGKHCELNSY 2241

Query: 428  ECEE 439
              EE
Sbjct: 2242 GFEE 2245



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY---CEL 170
            + C C   +TG  CE D  + C  + C++GA C ++  G ++C C  GY G +   CEL
Sbjct: 2182 FSCSCPDGFTGRACERDINE-CLQSPCKNGAIC-QNFPGSFNCVCKTGYTGVFGKHCEL 2238



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 17/47 (36%), Positives = 27/47 (57%)
 Frame = +3

Query: 123  YSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            + C C PGY G++CE+++     C+  PC + G+C    GG + S P
Sbjct: 2144 FLCKCLPGYAGSWCEIDID---ECLPSPCHSGGTCHNLVGGFSCSCP 2187



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
 Frame = +3

Query: 15   CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS-LDPL 191
            C  ++    C V  GD CAS  C++G  C       ++C CP  + G  CE+ V+ L  L
Sbjct: 2656 CINQWYAYRC-VPPGD-CASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVACLGVL 2713

Query: 192  CVAGPCRNNGS-----CSVPPGGDTYSAPV 266
            C  G     GS     C +  G +  S P+
Sbjct: 2714 CPQGKVCKAGSPAGHVCVLSQGPEEISLPL 2743


>BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1534

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-D 185
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C    +L +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAE 1420

Query: 186  PL----CVAGPCRNNGS----CSVPPG 242
            P     C+ G C+ +G+    C   PG
Sbjct: 1421 PCRGLQCLHGHCQASGTKGAHCVCDPG 1447



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVN 427
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C     
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALCNQAGA 1417

Query: 428  ECEEDRAL-CGHGVCYDT-YGGFVCACQPATPG 520
              E  R L C HG C  +   G  C C P   G
Sbjct: 1418 LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSG 1450



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG---DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y+G  C   AG   +PC    C HG  C   G     C C PG+ G  CE E
Sbjct: 1399 YSCQCQDGYSGALCN-QAGALAEPCRGLQCLHG-HCQASGTKGAHCVCDPGFSGELCEQE 1456


>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1534

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-D 185
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C    +L +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAE 1420

Query: 186  PL----CVAGPCRNNGS----CSVPPG 242
            P     C+ G C+ +G+    C   PG
Sbjct: 1421 PCRGLQCLHGHCQASGTKGAHCVCDPG 1447



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVN 427
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C     
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALCNQAGA 1417

Query: 428  ECEEDRAL-CGHGVCYDT-YGGFVCACQPATPG 520
              E  R L C HG C  +   G  C C P   G
Sbjct: 1418 LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSG 1450



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG---DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y+G  C   AG   +PC    C HG  C   G     C C PG+ G  CE E
Sbjct: 1399 YSCQCQDGYSGALCN-QAGALAEPCRGLQCLHG-HCQASGTKGAHCVCDPGFSGELCEQE 1456


>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1461

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 22/52 (42%), Positives = 26/52 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALC 1412



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARC 412
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALC 1412


>AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1534

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-D 185
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C    +L +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAE 1420

Query: 186  PL----CVAGPCRNNGS----CSVPPG 242
            P     C+ G C+ +G+    C   PG
Sbjct: 1421 PCRGLQCLHGHCQASGTKGAHCVCDPG 1447



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVN 427
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C     
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALCNQAGA 1417

Query: 428  ECEEDRAL-CGHGVCYDT-YGGFVCACQPATPG 520
              E  R L C HG C  +   G  C C P   G
Sbjct: 1418 LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSG 1450



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG---DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y+G  C   AG   +PC    C HG  C   G     C C PG+ G  CE E
Sbjct: 1399 YSCQCQDGYSGALCN-QAGALAEPCRGLQCLHG-HCQASGTKGAHCVCDPGFSGELCEQE 1456


>AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1461

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 22/52 (42%), Positives = 26/52 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALC 1412



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARC 412
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALC 1412


>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
          Length = 1534

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 991  CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1048

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1049 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1081



 Score = 73.3 bits (172), Expect = 6e-13
 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  ++ CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 950  CACPSGYKGRDCEVSLNSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1007

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1008 DC-VDHACANGGVCVDGVGNYTCQC 1031



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1069 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1126

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1127 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1159



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   + C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 948  YRCACPSGYKGRDCEVSL-NSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1004

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1005 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1036



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 989  FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1047 CSPDL-NPCQHEAQCVGTPDG 1066



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 27/63 (42%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSL+  C +GPC N G+C    
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLNS-CSSGPCENGGTCHAQE 983

Query: 240  GGD 248
            G D
Sbjct: 984  GED 986



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1069 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1126

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1127 PKSPCEGTECQNGANC 1142



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-D 185
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C    +L +
Sbjct: 1362 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAE 1420

Query: 186  PL----CVAGPCRNNGS----CSVPPG 242
            P     C+ G C+ +G+    C   PG
Sbjct: 1421 PCRGLQCLHGHCQASGTKGAHCVCDPG 1447



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1163

Query: 168  LEVSLD 185
              +S++
Sbjct: 1164 KLLSVN 1169



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVN 427
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C     
Sbjct: 1361 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALCNQAGA 1417

Query: 428  ECEEDRAL-CGHGVCYDT-YGGFVCACQPATPG 520
              E  R L C HG C  +   G  C C P   G
Sbjct: 1418 LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSG 1450



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG---DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y+G  C   AG   +PC    C HG  C   G     C C PG+ G  CE E
Sbjct: 1399 YSCQCQDGYSGALCN-QAGALAEPCRGLQCLHG-HCQASGTKGAHCVCDPGFSGELCEQE 1456


>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
          Length = 1618

 Score = 78.2 bits (184), Expect = 2e-14
 Identities = 38/93 (40%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G  C  + D+C   A C NGG CVD V NYTC C    Y G  CE  V+ C 
Sbjct: 1075 CSCPTGFEGPTCGVNTDDCVDHA-CANGGVCVDGVGNYTCQCPLQ-YEGKACEQLVDLCS 1132

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPGSTAT 532
             D   C H   C  T  G  C C P   G   +
Sbjct: 1133 PDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCS 1165



 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 35/85 (41%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN---YTCDCTATGYTGARCETNVN 427
            C CP GY GR+CE  +D CS +  C NGG C         +TC C  TG+ G  C  N +
Sbjct: 1034 CACPSGYKGRDCEVSLDSCS-SGPCENGGTCHAQEGEDAPFTCSC-PTGFEGPTCGVNTD 1091

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            +C  D A    GVC D  G + C C
Sbjct: 1092 DC-VDHACANGGVCVDGVGNYTCQC 1115



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE------T 418
            C C PGY G NC  + D+C     C NG +C+D VN+Y+C C A GY+G  CE       
Sbjct: 1153 CECMPGYAGDNCSENQDDCRD-HRCQNGAQCMDEVNSYSCLC-AEGYSGQLCEIPPHLPA 1210

Query: 419  NVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
              + CE     C +G  C D     VC C P   G
Sbjct: 1211 PKSPCEGTE--CQNGANCVDQGNRPVCQCLPGFGG 1243



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGR-GDYSCDCPPGYHGTYCELEV 176
            Y C C + Y G +CEV   D C+S  C +G  C  ++G    ++C CP G+ G  C   V
Sbjct: 1032 YRCACPSGYKGRDCEVSL-DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTC--GV 1088

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
            + D  CV   C N G C    G  T   P++ +
Sbjct: 1089 NTDD-CVDHACANGGVCVDGVGNYTCQCPLQYE 1120



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   + G  C V+  D C   AC +G  CV DG G+Y+C CP  Y G  CE  V L
Sbjct: 1073 FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVCV-DGVGNYTCQCPLQYEGKACEQLVDL 1130

Query: 183  DPLCVAGPCRNNGSCSVPPGG 245
                +  PC++   C   P G
Sbjct: 1131 CSPDL-NPCQHEAQCVGTPDG 1150



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 28/63 (44%), Positives = 33/63 (52%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C S+ C++   C  D    Y C CP GY G  C  EVSLD  C +GPC N G+C    
Sbjct: 1011 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC--EVSLDS-CSSGPCENGGTCHAQE 1067

Query: 240  GGD 248
            G D
Sbjct: 1068 GED 1070



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-- 182
            C C   Y G+NC  +  D C    C++GA+C+++    YSC C  GY G  CE+   L  
Sbjct: 1153 CECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNS-YSCLCAEGYSGQLCEIPPHLPA 1210

Query: 183  -DPLCVAGPCRNNGSC 227
                C    C+N  +C
Sbjct: 1211 PKSPCEGTECQNGANC 1226



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL-D 185
            CHC A + G +C+  A  PC    C HG +CV      YSC C  GY G  C    +L +
Sbjct: 1446 CHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAE 1504

Query: 186  PL----CVAGPCRNNGS----CSVPPG 242
            P     C+ G C+ +G+    C   PG
Sbjct: 1505 PCRGLQCLHGHCQASGTKGAHCVCDPG 1531



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG-----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   Y+G  CE+         PC    C++GA CV+ G     C C PG+ G  CE
Sbjct: 1189 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPV-CQCLPGFGGPECE 1247

Query: 168  LEVSLD 185
              +S++
Sbjct: 1248 KLLSVN 1253



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVN 427
            +C C  G+ G +C+   D       C++ G+CV  DA+ +Y+C C   GY+GA C     
Sbjct: 1445 MCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLDAL-SYSCQC-QDGYSGALCNQAGA 1501

Query: 428  ECEEDRAL-CGHGVCYDT-YGGFVCACQPATPG 520
              E  R L C HG C  +   G  C C P   G
Sbjct: 1502 LAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSG 1534



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG---DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y+G  C   AG   +PC    C HG  C   G     C C PG+ G  CE E
Sbjct: 1483 YSCQCQDGYSGALCN-QAGALAEPCRGLQCLHG-HCQASGTKGAHCVCDPGFSGELCEQE 1540


>BC000218-1|AAH00218.1|  618|Homo sapiens delta-like 3 (Drosophila)
           protein.
          Length = 618

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 37/92 (40%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           L C C  G+ G  CE D+D+C+G  AC NGG CV+    + C C A G+ G  C    + 
Sbjct: 375 LRCRCRAGFAGPRCEHDLDDCAG-RACANGGTCVEGGGAHRCSC-ALGFGGRDCRERADP 432

Query: 431 CEEDRALCGH-GVCYDTYGGFVCACQPATPGS 523
           C      C H G CY  + G VCAC P   G+
Sbjct: 433 CA--ARPCAHGGRCYAHFSGLVCACAPGYMGA 462



 Score = 77.0 bits (181), Expect = 5e-14
 Identities = 35/83 (42%), Positives = 46/83 (55%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPPG+ G NCE  VD CS    C NGG C+D  +   C C A G+ G RCE ++++C
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCS-LQPCRNGGLCLDLGHALRCRCRA-GFAGPRCEHDLDDC 395

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
              RA    G C +  G   C+C
Sbjct: 396 -AGRACANGGTCVEGGGAHRCSC 417



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 32/77 (41%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
           +EC C   + G  CEV +G  CA   C +G  CV     D  Y C CPPG+ G+ CE  V
Sbjct: 296 FECTCPRGFYGLRCEV-SGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV 354

Query: 177 SLDPLCVAGPCRNNGSC 227
                C   PCRN G C
Sbjct: 355 D---RCSLQPCRNGGLC 368



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/73 (42%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A + G  CE D  D CA  AC +G  CVE G G + C C  G+ G  C      DP
Sbjct: 377 CRCRAGFAGPRCEHDLDD-CAGRACANGGTCVEGG-GAHRCSCALGFGGRDCRERA--DP 432

Query: 189 LCVAGPCRNNGSC 227
            C A PC + G C
Sbjct: 433 -CAARPCAHGGRC 444



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCE 415
           R   CTCP G+ G  CE     C+    C NGG CV   D  + Y C C   G+ G+ CE
Sbjct: 294 RSFECTCPRGFYGLRCEVSGVTCAD-GPCFNGGLCVGGADPDSAYICHC-PPGFQGSNCE 351

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             V+ C       G G+C D      C C+    G
Sbjct: 352 KRVDRCSLQPCRNG-GLCLDLGHALRCRCRAGFAG 385



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y CHC   + G+NCE    D C+   CR+G  C++ G     C C  G+ G  CE +  L
Sbjct: 337 YICHCPPGFQGSNCEKRV-DRCSLQPCRNGGLCLDLGHA-LRCRCRAGFAGPRCEHD--L 392

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C    C N G+C V  GG
Sbjct: 393 DD-CAGRACANGGTC-VEGGG 411



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 24/61 (39%), Positives = 29/61 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C  +  DPCA+  C HG RC     G   C C PGY G  CE  V  
Sbjct: 413 HRCSCALGFGGRDCR-ERADPCAARPCAHGGRCYAHFSG-LVCACAPGYMGARCEFPVHP 470

Query: 183 D 185
           D
Sbjct: 471 D 471



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/57 (43%), Positives = 32/57 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           C+C  G+ GR+C    D C+ A  C +GGRC    +   C C A GY GARCE  V+
Sbjct: 415 CSCALGFGGRDCRERADPCA-ARPCAHGGRCYAHFSGLVCAC-APGYMGARCEFPVH 469



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 23/62 (37%), Positives = 28/62 (45%)
 Frame = +3

Query: 42  CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNG 221
           C V    PC    C +G  C E  R  + C CP G++G  CE+       C  GPC N G
Sbjct: 270 CLVPGPGPCDGNPCANGGSCSETPR-SFECTCPRGFYGLRCEVS---GVTCADGPCFNGG 325

Query: 222 SC 227
            C
Sbjct: 326 LC 327



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY---DTY 481
           C G   C NGG C +   ++ C C   G+ G RCE +   C +     G G+C    D  
Sbjct: 278 CDGNP-CANGGSCSETPRSFECTC-PRGFYGLRCEVSGVTCADGPCFNG-GLCVGGADPD 334

Query: 482 GGFVCACQPATPGS 523
             ++C C P   GS
Sbjct: 335 SAYICHCPPGFQGS 348


>AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC--TATGYTGARCETNVNE 430
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    +GYTGA+CE ++NE
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNE 230

Query: 431 CEED 442
           C  +
Sbjct: 231 CNSN 234



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1051 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1107

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1108 SHQ--CANGATCISHTNGYSCLC 1128



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 270 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 328

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 329 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 366



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1088 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1145

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1179



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHG-TYCELEVS 179
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G T  + E+ 
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGYTGAQCEID 227

Query: 180 LDPLCVAGPCRNNGSC 227
           L+  C + PC++NG C
Sbjct: 228 LNE-CNSNPCQSNGEC 242



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1169 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1224



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1036 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1092

Query: 509  ATPG 520
               G
Sbjct: 1093 GYTG 1096



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1086 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1141

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1142 LPSTVCGNEKTNLTC 1156



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1049 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1104

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1105 --NCQSHQCANGATC 1117



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 23/105 (21%)
 Frame = +2

Query: 257 CTCP---PGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNN 367
           C CP    GYTG  CE D++EC+ +  C + G CV+                      + 
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 268

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           Y C C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 269 YVCIC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 311



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1126 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1184

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1185 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1217



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
 Frame = +3

Query: 3   YECHCT---ARYTGNNCEVDAGDPCASAACRHGARCVE------DGR------------- 116
           Y C C    + YTG  CE+D  + C S  C+    CVE       GR             
Sbjct: 208 YTCICPHNYSGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 266

Query: 117 GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             Y C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 267 SGYVCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 269 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 326

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 327 S-DILLG--CTHQQCLNNGTC 344



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1031 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1080



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1124 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1182

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1183 EKDID---ECASDPCVNGGLC 1200



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 307 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 365

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 366 SLCEIATTL 374



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 774 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 827



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 784 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 839

Query: 506 PATPGST 526
               G +
Sbjct: 840 AVFNGQS 846



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 548 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 595


>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC--TATGYTGARCETNVNE 430
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    +GYTGA+CE ++NE
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNE 230

Query: 431 CEED 442
           C  +
Sbjct: 231 CNSN 234



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1051 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1107

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1108 SHQ--CANGATCISHTNGYSCLC 1128



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 270 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 328

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 329 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 366



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1088 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1145

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1179



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHG-TYCELEVS 179
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G T  + E+ 
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGYTGAQCEID 227

Query: 180 LDPLCVAGPCRNNGSC 227
           L+  C + PC++NG C
Sbjct: 228 LNE-CNSNPCQSNGEC 242



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1169 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1224



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1036 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1092

Query: 509  ATPG 520
               G
Sbjct: 1093 GYTG 1096



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1086 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1141

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1142 LPSTVCGNEKTNLTC 1156



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1049 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1104

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1105 --NCQSHQCANGATC 1117



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 23/105 (21%)
 Frame = +2

Query: 257 CTCP---PGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNN 367
           C CP    GYTG  CE D++EC+ +  C + G CV+                      + 
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 268

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           Y C C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 269 YVCIC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 311



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1126 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1184

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1185 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1217



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
 Frame = +3

Query: 3   YECHCT---ARYTGNNCEVDAGDPCASAACRHGARCVE------DGR------------- 116
           Y C C    + YTG  CE+D  + C S  C+    CVE       GR             
Sbjct: 208 YTCICPHNYSGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 266

Query: 117 GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             Y C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 267 SGYVCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 269 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 326

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 327 S-DILLG--CTHQQCLNNGTC 344



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1031 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1080



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1124 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1182

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1183 EKDID---ECASDPCVNGGLC 1200



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 307 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 365

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 366 SLCEIATTL 374



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 774 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 827



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 784 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 839

Query: 506 PATPGST 526
               G +
Sbjct: 840 AVFNGQS 846



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 548 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 595


>AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 1294

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC--TATGYTGARCETNVNE 430
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    +GYTGA+CE ++NE
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNE 230

Query: 431 CEED 442
           C  +
Sbjct: 231 CNSN 234



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1051 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1107

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1108 SHQ--CANGATCISHTNGYSCLC 1128



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 270 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 328

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 329 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 366



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1088 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1145

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1179



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHG-TYCELEVS 179
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G T  + E+ 
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGYTGAQCEID 227

Query: 180 LDPLCVAGPCRNNGSC 227
           L+  C + PC++NG C
Sbjct: 228 LNE-CNSNPCQSNGEC 242



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1169 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1224



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1036 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1092

Query: 509  ATPG 520
               G
Sbjct: 1093 GYTG 1096



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1086 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1141

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1142 LPSTVCGNEKTNLTC 1156



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1049 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1104

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1105 --NCQSHQCANGATC 1117



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 23/105 (21%)
 Frame = +2

Query: 257 CTCP---PGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNN 367
           C CP    GYTG  CE D++EC+ +  C + G CV+                      + 
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 268

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           Y C C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 269 YVCIC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 311



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1126 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1184

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1185 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1217



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
 Frame = +3

Query: 3   YECHCT---ARYTGNNCEVDAGDPCASAACRHGARCVE------DGR------------- 116
           Y C C    + YTG  CE+D  + C S  C+    CVE       GR             
Sbjct: 208 YTCICPHNYSGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 266

Query: 117 GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             Y C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 267 SGYVCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 269 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 326

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 327 S-DILLG--CTHQQCLNNGTC 344



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1031 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1080



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1124 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1182

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1183 EKDID---ECASDPCVNGGLC 1200



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 307 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 365

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 366 SLCEIATTL 374



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 774 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 827



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 784 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 839

Query: 506 PATPGST 526
               G +
Sbjct: 840 AVFNGQS 846



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 548 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 595


>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
           (alternative protein) protein.
          Length = 1294

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 45/73 (61%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A Y G  CE+D  D CAS+ C++GA C +DG   YSC C PGY G +C+LEV    
Sbjct: 134 CICPAGYAGRFCEIDH-DECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVD--- 188

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N  +C
Sbjct: 189 ECASDPCKNEATC 201



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 38/95 (40%), Positives = 45/95 (47%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P  R  LC CPPGY+G  CET +  C G  +C +GG C        C C A GY G  CE
Sbjct: 89  PGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPA-GYAGRFCE 146

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            + +EC       G  VC D   G+ C C P   G
Sbjct: 147 IDHDECASSPCQNG-AVCQDGIDGYSCFCVPGYQG 180



 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 29/64 (45%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC--TATGYTGARCETNVNE 430
           C C PGY GR+C+ +VDEC+ +  C N   C++ +  YTC C    +GYTGA+CE ++NE
Sbjct: 172 CFCVPGYQGRHCDLEVDECA-SDPCKNEATCLNEIGRYTCICPHNYSGYTGAQCEIDLNE 230

Query: 431 CEED 442
           C  +
Sbjct: 231 CNSN 234



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 1051 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 1107

Query: 437  EDRALCGHG-VCYDTYGGFVCAC 502
              +  C +G  C     G+ C C
Sbjct: 1108 SHQ--CANGATCISHTNGYSCLC 1128



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 38/99 (38%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-----TATGYTGARCET 418
           +C C PG+TG +CE DV+ECS +  C NGG C +   NYTC C     + T Y G  C  
Sbjct: 270 VCICQPGFTGIHCEEDVNECS-SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 328

Query: 419 NVNECEEDRALCGHGVC----YDTYGGFVCACQPATPGS 523
            +  C   + L  +G C     D   GF C C     GS
Sbjct: 329 ILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGS 366



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
            CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 1088 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 1145

Query: 422  VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
            V   E+    C   G C +      C C+P   G
Sbjct: 1146 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 1179



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHG-TYCELEVS 179
           Y C C   Y G +C+++  D CAS  C++ A C+ +  G Y+C CP  Y G T  + E+ 
Sbjct: 170 YSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNE-IGRYTCICPHNYSGYTGAQCEID 227

Query: 180 LDPLCVAGPCRNNGSC 227
           L+  C + PC++NG C
Sbjct: 228 LNE-CNSNPCQSNGEC 242



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 26/58 (44%), Positives = 36/58 (62%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            L C C PG+TG  CE D+DEC+ +  C+NGG C D +N + C C    + G RCE ++
Sbjct: 1169 LKCMCRPGFTGEWCEKDIDECA-SDPCVNGGLCQDLLNKFQCLCD-VAFAGERCEVDL 1224



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 1036 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 1092

Query: 509  ATPG 520
               G
Sbjct: 1093 GYTG 1096



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/83 (36%), Positives = 39/83 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y+G  CE   G  C   +C+HG  C +D      C CP GY G +CE++     
Sbjct: 96  CKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEID---HD 150

Query: 189 LCVAGPCRNNGSCSVPPGGDTYS 257
            C + PC+N   C    G D YS
Sbjct: 151 ECASSPCQNGAVCQ--DGIDGYS 171



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAG---DPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSL 182
           C+   T NN + D     DPC S  C+  A CV   G   + C CPPGY GT CE  +  
Sbjct: 54  CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIG- 112

Query: 183 DPLCVAGPCRNNGSCSVPP 239
              C    C++ G C   P
Sbjct: 113 --SCGKNSCQHGGICHQDP 129



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 1086 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 1141

Query: 183  DPLCVAGPCRNNGSC 227
             P  V G  + N +C
Sbjct: 1142 LPSTVCGNEKTNLTC 1156



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 1049 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 1104

Query: 183  DPLCVAGPCRNNGSC 227
               C +  C N  +C
Sbjct: 1105 --NCQSHQCANGATC 1117



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 23/105 (21%)
 Frame = +2

Query: 257 CTCP---PGYTGRNCETDVDECSGAAACLNGGRCVD--------------------AVNN 367
           C CP    GYTG  CE D++EC+ +  C + G CV+                      + 
Sbjct: 210 CICPHNYSGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 268

Query: 368 YTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           Y C C   G+TG  CE +VNEC  +    G G C +  G + C C
Sbjct: 269 YVCIC-QPGFTGIHCEEDVNECSSNPCQNG-GTCENLPGNYTCHC 311



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETD---VDECSGAAA---CLNGGRCVDAVNNYTCDCTATGYTGARCET 418
            C C   +TG+ C         C        C NGG C +      C C   G+TG  CE 
Sbjct: 1126 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP-GFTGEWCEK 1184

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +++EC  D  + G G+C D    F C C  A  G
Sbjct: 1185 DIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAG 1217



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
 Frame = +3

Query: 3   YECHCT---ARYTGNNCEVDAGDPCASAACRHGARCVE------DGR------------- 116
           Y C C    + YTG  CE+D  + C S  C+    CVE       GR             
Sbjct: 208 YTCICPHNYSGYTGAQCEIDLNE-CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 266

Query: 117 GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             Y C C PG+ G +CE +V+    C + PC+N G+C   PG  T   P
Sbjct: 267 SGYVCICQPGFTGIHCEEDVNE---CSSNPCQNGGTCENLPGNYTCHCP 312



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP------PGYHGTYC 164
           Y C C   +TG +CE D  + C+S  C++G  C E+  G+Y+C CP        Y G  C
Sbjct: 269 YVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTC-ENLPGNYTCHCPFDNLSRTFYGGRDC 326

Query: 165 ELEVSLDPLCVAGPCRNNGSC 227
             ++ L   C    C NNG+C
Sbjct: 327 S-DILLG--CTHQQCLNNGTC 344



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
            C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 1031 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 1080



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVD------AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   +TG  C          G+   +  C +G  C E  + +  C C PG+ G +C
Sbjct: 1124 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWC 1182

Query: 165  ELEVSLDPLCVAGPCRNNGSC 227
            E ++     C + PC N G C
Sbjct: 1183 EKDID---ECASDPCVNGGLC 1200



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
 Frame = +3

Query: 3   YECHCT------ARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHG 155
           Y CHC         Y G +C  D    C    C +   C+   +DG+  +SC CP GY G
Sbjct: 307 YTCHCPFDNLSRTFYGGRDCS-DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTG 365

Query: 156 TYCELEVSL 182
           + CE+  +L
Sbjct: 366 SLCEIATTL 374



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/59 (27%), Positives = 28/59 (47%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
           C S +C++ + C +D   D  C C    +    + +   DP C + PC+ + +C   PG
Sbjct: 34  CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPG 90



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 774 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 827



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 784 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 839

Query: 506 PATPGST 526
               G +
Sbjct: 840 AVFNGQS 846



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%)
 Frame = +2

Query: 326 ACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDRALCGHGVCYDTYG--GFVC 496
           +C N   C D   +  C C+ T       C+   + C  +    G   C +T G   F+C
Sbjct: 38  SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ-GSATCVNTPGERSFLC 96

Query: 497 ACQPATPGS 523
            C P   G+
Sbjct: 97  KCPPGYSGT 105



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 548 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 595


>AF241373-1|AAF62542.1|  618|Homo sapiens DLL3 protein precursor
           protein.
          Length = 618

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 37/92 (40%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           L C C  G+ G  CE D+D+C+G  AC NGG CV+    + C C A G+ G  C    + 
Sbjct: 375 LRCRCRAGFAGPRCEHDLDDCAG-RACANGGTCVEGGGAHRCSC-ALGFGGRDCRERADP 432

Query: 431 CEEDRALCGH-GVCYDTYGGFVCACQPATPGS 523
           C      C H G CY  + G VCAC P   G+
Sbjct: 433 CA--ARPCAHGGRCYAHFSGLVCACAPGYMGA 462



 Score = 77.0 bits (181), Expect = 5e-14
 Identities = 35/83 (42%), Positives = 46/83 (55%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPPG+ G NCE  VD CS    C NGG C+D  +   C C A G+ G RCE ++++C
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCS-LQPCRNGGLCLDLGHALRCRCRA-GFAGPRCEHDLDDC 395

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
              RA    G C +  G   C+C
Sbjct: 396 -AGRACANGGTCVEGGGAHRCSC 417



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 32/77 (41%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
           +EC C   + G  CEV +G  CA   C +G  CV     D  Y C CPPG+ G+ CE  V
Sbjct: 296 FECTCPRGFYGLRCEV-SGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV 354

Query: 177 SLDPLCVAGPCRNNGSC 227
                C   PCRN G C
Sbjct: 355 D---RCSLQPCRNGGLC 368



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 31/73 (42%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A + G  CE D  D CA  AC +G  CVE G G + C C  G+ G  C      DP
Sbjct: 377 CRCRAGFAGPRCEHDLDD-CAGRACANGGTCVEGG-GAHRCSCALGFGGRDCRERA--DP 432

Query: 189 LCVAGPCRNNGSC 227
            C A PC + G C
Sbjct: 433 -CAARPCAHGGRC 444



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCE 415
           R   CTCP G+ G  CE     C+    C NGG CV   D  + Y C C   G+ G+ CE
Sbjct: 294 RSFECTCPRGFYGLRCEVSGVTCAD-GPCFNGGLCVGGADPDSAYICHC-PPGFQGSNCE 351

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             V+ C       G G+C D      C C+    G
Sbjct: 352 KRVDRCSLQPCRNG-GLCLDLGHALRCRCRAGFAG 385



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y CHC   + G+NCE    D C+   CR+G  C++ G     C C  G+ G  CE +  L
Sbjct: 337 YICHCPPGFQGSNCEKRV-DRCSLQPCRNGGLCLDLGHA-LRCRCRAGFAGPRCEHD--L 392

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C    C N G+C V  GG
Sbjct: 393 DD-CAGRACANGGTC-VEGGG 411



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 24/61 (39%), Positives = 29/61 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C  +  DPCA+  C HG RC     G   C C PGY G  CE  V  
Sbjct: 413 HRCSCALGFGGRDCR-ERADPCAARPCAHGGRCYAHFSG-LVCACAPGYMGARCEFPVHP 470

Query: 183 D 185
           D
Sbjct: 471 D 471



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/57 (43%), Positives = 32/57 (56%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           C+C  G+ GR+C    D C+ A  C +GGRC    +   C C A GY GARCE  V+
Sbjct: 415 CSCALGFGGRDCRERADPCA-ARPCAHGGRCYAHFSGLVCAC-APGYMGARCEFPVH 469



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 23/62 (37%), Positives = 28/62 (45%)
 Frame = +3

Query: 42  CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNG 221
           C V    PC    C +G  C E  R  + C CP G++G  CE+       C  GPC N G
Sbjct: 270 CLVPGPGPCDGNPCANGGSCSETPR-SFECTCPRGFYGLRCEVS---GVTCADGPCFNGG 325

Query: 222 SC 227
            C
Sbjct: 326 LC 327



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY---DTY 481
           C G   C NGG C +   ++ C C   G+ G RCE +   C +     G G+C    D  
Sbjct: 278 CDGNP-CANGGSCSETPRSFECTC-PRGFYGLRCEVSGVTCADGPCFNG-GLCVGGADPD 334

Query: 482 GGFVCACQPATPGS 523
             ++C C P   GS
Sbjct: 335 SAYICHCPPGFQGS 348


>AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.
          Length = 502

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 38/100 (38%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDEC----SGAAACLNGGRCVDAVNNYTCDCTA 388
           Q    P     LC C PGY+G  C  D+DEC     G + C +GG C++   ++ C C  
Sbjct: 405 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC-P 463

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            GYTG+RCE + NEC       G   C D    F C C P
Sbjct: 464 PGYTGSRCEADHNECLSQPCHPG-STCLDLLATFHCLCPP 502



 Score = 77.0 bits (181), Expect = 5e-14
 Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC CPPG+ G  CE + D C  +  C NGG C D ++ YTC C  T +TG  C  +V+EC
Sbjct: 260 LCLCPPGFIGPGCEVNPDNCV-SHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDEC 317

Query: 434 E-EDRALCGH-GVCYDTYGGFVCACQPATPGST 526
           E +    C + G C ++ G F C C     G++
Sbjct: 318 EAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 350



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 29/79 (36%), Positives = 42/79 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG  G  C LE   
Sbjct: 338 FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPGRTGLLCHLE--- 392

Query: 183 DPLCVAGPCRNNGSCSVPP 239
             +C++ PC  +  CS  P
Sbjct: 393 -DMCLSQPCHGDAQCSTNP 410



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
 Frame = +2

Query: 233 APRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGAR 409
           +P     LCTC PG+TG  C+  +++    + C   GRC + A     C C   G+TG +
Sbjct: 94  SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC-MPGWTGEQ 152

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           C+   + C  +  + G GVC  TY    C C P   G
Sbjct: 153 CQLR-DFCSANPCVNG-GVCLATYPQIQCHCPPGFEG 187



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/73 (35%), Positives = 31/73 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+    DPC  + C    RC     G   C C PG+ G  C+L      
Sbjct: 102 CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR----D 157

Query: 189 LCVAGPCRNNGSC 227
            C A PC N G C
Sbjct: 158 FCSANPCVNGGVC 170



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCV---EDGRGDYSCDCPPGYHGTYCELE 173
           ++C C     G  CE+ AG PC    C +G  C    E     + C CPPG+ G  C  E
Sbjct: 217 FQCLCPVGQEGPRCELRAG-PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGC--E 273

Query: 174 VSLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           V+ D  CV+  C+N G+C    G DTY+
Sbjct: 274 VNPDN-CVSHQCQNGGTCQ--DGLDTYT 298



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DV+EC      C  G  C + + ++ C C   G  G RCE     C
Sbjct: 179 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC-PVGQEGPRCELRAGPC 237

Query: 434 EEDRALCGHGVCY---DTYGGF-VCACQPATPGSTATGC 538
              R     G C    +    F +C C    PG    GC
Sbjct: 238 -PPRGCSNGGTCQLMPEKDSTFHLCLC---PPGFIGPGC 272



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C   G TG  C  ++ +  
Sbjct: 340 CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC-PPGRTGLLC--HLEDMC 395

Query: 437 EDRALCGHGVCYDT--YGGFVCACQPATPGST 526
             +   G   C      G  +C CQP   G T
Sbjct: 396 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPT 427



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G  CEV+  D C S  C++G  C +DG   Y+C CP  + G  C  +V  D 
Sbjct: 261 CLCPPGFIGPGCEVNP-DNCVSHQCQNGGTC-QDGLDTYTCLCPETWTGWDCSEDV--DE 316

Query: 189 LCVAGP--CRNNGSCSVPPG 242
               GP  CRN G+C    G
Sbjct: 317 CEAQGPPHCRNGGTCQNSAG 336



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG TG  C  + D C  +  C    +C  + +   T      GY+G  C  +++EC
Sbjct: 378 CLCPPGRTGLLCHLE-DMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 435

Query: 434 ---EEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
              ++  + C HG  C +T G F C C P   GS
Sbjct: 436 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS 469



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-----CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           C C   Y+G  C  D  D C  A      C HG  C+    G ++C CPPGY G+ CE +
Sbjct: 417 CLCQPGYSGPTCHQDL-DECLMAQQGPSPCEHGGSCLNTP-GSFNCLCPPGYTGSRCEAD 474

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +    C++ PC    +C
Sbjct: 475 HN---ECLSQPCHPGSTC 489



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C C   +TG  C++   D C++  C +G  C+        C CPPG+ G  CE +V+ +
Sbjct: 141 QCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLAT-YPQIQCHCPPGFEGHACERDVN-E 196

Query: 186 PLCVAGPCRNNGSCSVPPGGDTYSAPVRQD 275
                GPC    SC    G      PV Q+
Sbjct: 197 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE 226



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           +CHC   + G+ CE D  +       C  G  C  +  G + C CP G  G  CEL    
Sbjct: 178 QCHCPPGFEGHACERDVNECFQDPGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAG- 235

Query: 183 DPLCVAGPCRNNGSCSVPPGGDT 251
            P C    C N G+C + P  D+
Sbjct: 236 -P-CPPRGCSNGGTCQLMPEKDS 256



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   +TG +C  D  D C +     CR+G  C ++  G + C C  G+ GT C  E
Sbjct: 297 YTCLCPETWTGWDCSEDV-DECEAQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--E 352

Query: 174 VSLDPLCVAGPCRNNGSC 227
            +LD  C+A  C    +C
Sbjct: 353 ENLDD-CIAATCAPGSTC 369



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVS 179
           + C C    TG  C ++  D C S  C   A+C  +   G   C C PGY G  C  ++ 
Sbjct: 376 FSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 433

Query: 180 LDPLCVAG--PCRNNGSCSVPPG 242
              +   G  PC + GSC   PG
Sbjct: 434 ECLMAQQGPSPCEHGGSCLNTPG 456



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 15/103 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--------------VDAVNNYTCDCTATG 394
           C C PG+ G  C+   D C  A  C NGG C                   ++ C C   G
Sbjct: 50  CQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTC-LPG 107

Query: 395 YTGARCETNVNECEEDRALCGHGVCY-DTYGGFVCACQPATPG 520
           +TG RC+  + +          G C+    G   C+C P   G
Sbjct: 108 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 150



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           + C C   YTG+ CE D  + C S  C  G+ C+ D    + C CPP
Sbjct: 458 FNCLCPPGYTGSRCEADHNE-CLSQPCHPGSTCL-DLLATFHCLCPP 502



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +G  C+    G  +C C PG+ G  C+     DP   A  C+N GSC
Sbjct: 34  CANGGTCLSLSLGQGTCQCAPGFLGETCQFP---DPCQNAQLCQNGGSC 79



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAA-CRHGARC---VEDGRG----------DYSCDCPPG 146
           C C   + G  C+    DPC +A  C++G  C   +    G           + C C PG
Sbjct: 50  CQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 107

Query: 147 YHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           + G  C+ ++  DP C    C   G C +   G
Sbjct: 108 FTGERCQAKLE-DP-CPPSFCSKRGRCHIQASG 138


>AK075302-1|BAC11535.1|  587|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to
           Delta-like protein 3 precursor. ).
          Length = 587

 Score = 77.4 bits (182), Expect = 4e-14
 Identities = 37/92 (40%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +2

Query: 251 LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           L C C  G+ G  CE D+D+C+G  AC NGG CV+    + C C A G+ G  C    + 
Sbjct: 375 LRCRCRAGFAGPRCEHDLDDCAG-RACANGGTCVEGGGAHRCSC-ALGFGGRDCRERADP 432

Query: 431 CEEDRALCGH-GVCYDTYGGFVCACQPATPGS 523
           C      C H G CY  + G VCAC P   G+
Sbjct: 433 CAV--RPCAHGGRCYAHFSGLVCACAPGYMGA 462



 Score = 77.0 bits (181), Expect = 5e-14
 Identities = 35/83 (42%), Positives = 46/83 (55%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPPG+ G NCE  VD CS    C NGG C+D  +   C C A G+ G RCE ++++C
Sbjct: 338 ICHCPPGFQGSNCEKRVDRCS-LQPCRNGGLCLDLGHALRCRCRA-GFAGPRCEHDLDDC 395

Query: 434 EEDRALCGHGVCYDTYGGFVCAC 502
              RA    G C +  G   C+C
Sbjct: 396 -AGRACANGGTCVEGGGAHRCSC 417



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
           +EC C   + G  CEV +G  CA+  C +G  CV     D  Y C CPPG+ G+ CE  V
Sbjct: 296 FECTCPRGFYGLRCEV-SGVTCANGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV 354

Query: 177 SLDPLCVAGPCRNNGSC 227
                C   PCRN G C
Sbjct: 355 D---RCSLQPCRNGGLC 368



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
 Frame = +2

Query: 245 RHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCE 415
           R   CTCP G+ G  CE     C+    C NGG CV   D  + Y C C   G+ G+ CE
Sbjct: 294 RSFECTCPRGFYGLRCEVSGVTCAN-GPCFNGGLCVGGADPDSAYICHC-PPGFQGSNCE 351

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
             V+ C       G G+C D      C C+    G
Sbjct: 352 KRVDRCSLQPCRNG-GLCLDLGHALRCRCRAGFAG 385



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/73 (41%), Positives = 35/73 (47%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C A + G  CE D  D CA  AC +G  CVE G G + C C  G+ G  C      DP
Sbjct: 377 CRCRAGFAGPRCEHDLDD-CAGRACANGGTCVEGG-GAHRCSCALGFGGRDCRERA--DP 432

Query: 189 LCVAGPCRNNGSC 227
            C   PC + G C
Sbjct: 433 -CAVRPCAHGGRC 444



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/81 (38%), Positives = 40/81 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y CHC   + G+NCE    D C+   CR+G  C++ G     C C  G+ G  CE +  L
Sbjct: 337 YICHCPPGFQGSNCEKRV-DRCSLQPCRNGGLCLDLGHA-LRCRCRAGFAGPRCEHD--L 392

Query: 183 DPLCVAGPCRNNGSCSVPPGG 245
           D  C    C N G+C V  GG
Sbjct: 393 DD-CAGRACANGGTC-VEGGG 411



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 24/61 (39%), Positives = 28/61 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G +C  +  DPCA   C HG RC     G   C C PGY G  CE  V  
Sbjct: 413 HRCSCALGFGGRDCR-ERADPCAVRPCAHGGRCYAHFSG-LVCACAPGYMGARCEFPVHP 470

Query: 183 D 185
           D
Sbjct: 471 D 471



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 24/57 (42%), Positives = 31/57 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           C+C  G+ GR+C    D C+    C +GGRC    +   C C A GY GARCE  V+
Sbjct: 415 CSCALGFGGRDCRERADPCA-VRPCAHGGRCYAHFSGLVCAC-APGYMGARCEFPVH 469



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 23/62 (37%), Positives = 28/62 (45%)
 Frame = +3

Query: 42  CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNG 221
           C V    PC    C +G  C E  R  + C CP G++G  CE+       C  GPC N G
Sbjct: 270 CLVPGPGPCDGNPCANGGSCSETPR-SFECTCPRGFYGLRCEVS---GVTCANGPCFNGG 325

Query: 222 SC 227
            C
Sbjct: 326 LC 327



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
 Frame = +2

Query: 311 CSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY---DTY 481
           C G   C NGG C +   ++ C C   G+ G RCE +   C       G G+C    D  
Sbjct: 278 CDGNP-CANGGSCSETPRSFECTC-PRGFYGLRCEVSGVTCANGPCFNG-GLCVGGADPD 334

Query: 482 GGFVCACQPATPGS 523
             ++C C P   GS
Sbjct: 335 SAYICHCPPGFQGS 348


>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila)
            protein.
          Length = 1523

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G+ CE + D+C     C N   CVD +NNY C C    YTG  C+  ++ C 
Sbjct: 982  CSCPLGFEGQRCEINPDDCED-NDCENNATCVDGINNYVCIC-PPNYTGELCDEVIDHCV 1039

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             +  LC H   C     GF C C P   G
Sbjct: 1040 PELNLCQHEAKCIPLDKGFSCECVPGYSG 1068



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            +C CPP YTG  C+  +D C      C +  +C+     ++C+C   GY+G  CET+ ++
Sbjct: 1019 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCEC-VPGYSGKLCETDNDD 1077

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C   +  C HG  C DT  G+ C C     G
Sbjct: 1078 CVAHK--CRHGAQCVDTINGYTCTCPQGFSG 1106



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 29/67 (43%), Positives = 40/67 (59%)
 Frame = +2

Query: 215  QRQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATG 394
            Q + +  P  +   C C PGY+G+ CETD D+C  A  C +G +CVD +N YTC C   G
Sbjct: 1046 QHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV-AHKCRHGAQCVDTINGYTCTC-PQG 1103

Query: 395  YTGARCE 415
            ++G  CE
Sbjct: 1104 FSGPFCE 1110



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y+G  CE D  D C +  CRHGA+CV+   G Y+C CP G+ G +CE    +
Sbjct: 1058 FSCECVPGYSGKLCETD-NDDCVAHKCRHGAQCVDTING-YTCTCPQGFSGPFCEHPPPM 1115

Query: 183  DPL----CVAGPCRNNGSCSVPPGGDTYSAP 263
              L    C    C+N   C V     T   P
Sbjct: 1116 VLLQTSPCDQYECQNGAQCIVVQQEPTCRCP 1146



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 39/82 (47%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C+ +A DPC    C HG +CV  G   Y C C  GY G  C+ +     
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGT-SYMCKCAEGYGGDLCDNKNDSAN 1410

Query: 189  LCVAGPCRNNGSCSVPPGGDTY 254
             C A  C ++G C +   G+ Y
Sbjct: 1411 ACSAFKC-HHGQCHISDQGEPY 1431



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  C+ +  D C      C+H A+C+   +G +SC+C PGY G  CE + 
Sbjct: 1018 YVCICPPNYTGELCD-EVIDHCVPELNLCQHEAKCIPLDKG-FSCECVPGYSGKLCETD- 1074

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              +  CVA  CR+   C     G T + P
Sbjct: 1075 --NDDCVAHKCRHGAQCVDTINGYTCTCP 1101



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC--VDA-VNNYTCDCTATGYTGARCETNVN 427
            C CP  Y G++C   ++ C     C +GG C   D+  + ++C C   G+ G RCE N +
Sbjct: 941  CACPYSYKGKDCTVPINTCI-QNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRCEINPD 998

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    +VC C P   G
Sbjct: 999  DC-EDNDCENNATCVDGINNYVCICPPNYTG 1028



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
            L R+  +  ++C C PG+TG  C+ +  D C G     + G+CV    +Y C C A GY 
Sbjct: 1342 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC--HHGKCVATGTSYMCKC-AEGYG 1398

Query: 401  GARCETNVNECEEDRAL-CGHGVCY-DTYGGFVCACQPATPG 520
            G  C+   +      A  C HG C+    G   C CQP   G
Sbjct: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   Y G +C V   + C    C+HG  C + D   D +SC CP G+ G  CE+  
Sbjct: 939  YRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINP 997

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 998  D-D--CEDNDCENNATC 1011



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            + C C   + G  CE++  D C    C + A CV DG  +Y C CPP Y G  C+
Sbjct: 980  FSCSCPLGFEGQRCEINPDD-CEDNDCENNATCV-DGINNYVCICPPNYTGELCD 1032



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEV--DAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y G+ C+   D+ + C++  C HG +C    +G+  C C PG+ G +C+ E
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE 1446



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S+ C++   C +D    Y C CP  Y G  C + ++    C+  PC++ G+C
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN---TCIQNPCQHGGTC 970



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   ++G  CE      +    PC    C++GA+C+   + + +C CPPG+ G  C
Sbjct: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQ-EPTCRCPPGFAGPRC 1154

Query: 165  ELEVSLD 185
            E  ++++
Sbjct: 1155 EKLITVN 1161



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-------TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            CTCP G++G  CE            C     C NG +C+      TC C   G+ G RCE
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCD-QYECQNGAQCIVVQQEPTCRC-PPGFAGPRCE 1155



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 66   CASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S   C+HG  C    +    C+C PG+ G  C+ E + DP C+   C ++G C
Sbjct: 1332 CKSCTVCKHGL-CRSVEKDSVVCECRPGWTGPLCDQE-ARDP-CLGHRC-HHGKC 1382


>BC090943-1|AAH90943.1|  249|Homo sapiens NOTCH2NL protein protein.
          Length = 249

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 105 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 161

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G+C +  G + C C
Sbjct: 162 IP-GHCQHGGICLNLPGSYQCQC 183



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 142 CKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 200

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 201 PSPCVNG-GTCRQTGDFTFECNCLPET 226



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 140 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICL-NLPGSYQCQCLQGFTGQYCD---SL 195

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 196 YVPCAPSPCVNGGTC 210



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 64  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 119

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 120 DACLSHPCANGSTCT 134



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/80 (33%), Positives = 38/80 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 103 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 157

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G C   PG
Sbjct: 158 NECDIPGHCQHGGICLNLPG 177



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 25  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 81

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 82  PCFVSRPCLNGGTCHM-LSRDTY 103



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 25  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 81

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 82  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 113



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 64  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 121

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 122 CLSHP--CANGSTCTTVANQFSCKC 144



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 179 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 224



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 9   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 53


>BC065219-1|AAH65219.2|  236|Homo sapiens Notch homolog 2
           (Drosophila) N-terminal like protein.
          Length = 236

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G+C +  G + C C
Sbjct: 149 IP-GHCQHGGICLNLPGSYQCQC 170



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPET 213



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/80 (33%), Positives = 38/80 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G C   PG
Sbjct: 145 NECDIPGHCQHGGICLNLPG 164



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>BC019835-1|AAH19835.1|  236|Homo sapiens Notch homolog 2 N-terminal
           like protein protein.
          Length = 236

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G+C +  G + C C
Sbjct: 149 IP-GHCQHGGICLNLPGSYQCQC 170



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPET 213



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGICL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 27/80 (33%), Positives = 38/80 (47%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G C   PG
Sbjct: 145 NECDIPGHCQHGGICLNLPG 164



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
          Length = 1523

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G+ CE + D+C     C N   CVD +NNY C C    YTG  C+  ++ C 
Sbjct: 982  CSCPLGFEGQRCEINPDDCED-NDCENNATCVDGINNYVCIC-PPNYTGELCDEVIDHCV 1039

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             +  LC H   C     GF C C P   G
Sbjct: 1040 PELNLCQHEAKCIPLDKGFSCECVPGYSG 1068



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            +C CPP YTG  C+  +D C      C +  +C+     ++C+C   GY+G  CET+ ++
Sbjct: 1019 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCEC-VPGYSGKLCETDNDD 1077

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C   +  C HG  C DT  G+ C C     G
Sbjct: 1078 CVAHK--CRHGAQCVDTINGYTCTCPQGFSG 1106



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 29/67 (43%), Positives = 40/67 (59%)
 Frame = +2

Query: 215  QRQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATG 394
            Q + +  P  +   C C PGY+G+ CETD D+C  A  C +G +CVD +N YTC C   G
Sbjct: 1046 QHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV-AHKCRHGAQCVDTINGYTCTC-PQG 1103

Query: 395  YTGARCE 415
            ++G  CE
Sbjct: 1104 FSGPFCE 1110



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y+G  CE D  D C +  CRHGA+CV+   G Y+C CP G+ G +CE    +
Sbjct: 1058 FSCECVPGYSGKLCETD-NDDCVAHKCRHGAQCVDTING-YTCTCPQGFSGPFCEHPPPM 1115

Query: 183  DPL----CVAGPCRNNGSCSVPPGGDTYSAP 263
              L    C    C+N   C V     T   P
Sbjct: 1116 VLLQTSPCDQYECQNGAQCIVVQQEPTCRCP 1146



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 39/82 (47%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C+ +A DPC    C HG +CV  G   Y C C  GY G  C+ +     
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGT-SYMCKCAEGYGGDLCDNKNDSAN 1410

Query: 189  LCVAGPCRNNGSCSVPPGGDTY 254
             C A  C ++G C +   G+ Y
Sbjct: 1411 ACSAFKC-HHGQCHISDQGEPY 1431



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  C+ +  D C      C+H A+C+   +G +SC+C PGY G  CE + 
Sbjct: 1018 YVCICPPNYTGELCD-EVIDHCVPELNLCQHEAKCIPLDKG-FSCECVPGYSGKLCETD- 1074

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              +  CVA  CR+   C     G T + P
Sbjct: 1075 --NDDCVAHKCRHGAQCVDTINGYTCTCP 1101



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC--VDA-VNNYTCDCTATGYTGARCETNVN 427
            C CP  Y G++C   ++ C     C +GG C   D+  + ++C C   G+ G RCE N +
Sbjct: 941  CACPYSYKGKDCTVPINTCI-QNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRCEINPD 998

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    +VC C P   G
Sbjct: 999  DC-EDNDCENNATCVDGINNYVCICPPNYTG 1028



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
            L R+  +  ++C C PG+TG  C+ +  D C G     + G+CV    +Y C C A GY 
Sbjct: 1342 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC--HHGKCVATGTSYMCKC-AEGYG 1398

Query: 401  GARCETNVNECEEDRAL-CGHGVCY-DTYGGFVCACQPATPG 520
            G  C+   +      A  C HG C+    G   C CQP   G
Sbjct: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   Y G +C V   + C    C+HG  C + D   D +SC CP G+ G  CE+  
Sbjct: 939  YRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINP 997

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 998  D-D--CEDNDCENNATC 1011



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            + C C   + G  CE++  D C    C + A CV DG  +Y C CPP Y G  C+
Sbjct: 980  FSCSCPLGFEGQRCEINPDD-CEDNDCENNATCV-DGINNYVCICPPNYTGELCD 1032



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEV--DAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y G+ C+   D+ + C++  C HG +C    +G+  C C PG+ G +C+ E
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE 1446



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S+ C++   C +D    Y C CP  Y G  C + ++    C+  PC++ G+C
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN---TCIQNPCQHGGTC 970



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   ++G  CE      +    PC    C++GA+C+   + + +C CPPG+ G  C
Sbjct: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQ-EPTCRCPPGFAGPRC 1154

Query: 165  ELEVSLD 185
            E  ++++
Sbjct: 1155 EKLITVN 1161



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-------TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            CTCP G++G  CE            C     C NG +C+      TC C   G+ G RCE
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCD-QYECQNGAQCIVVQQEPTCRC-PPGFAGPRCE 1155



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 66   CASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S   C+HG  C    +    C+C PG+ G  C+ E + DP C+   C ++G C
Sbjct: 1332 CKSCTVCKHGL-CRSVEKDSVVCECRPGWTGPLCDQE-ARDP-CLGHRC-HHGKC 1382


>AF075240-1|AAD19336.1|  850|Homo sapiens SLIT1 protein protein.
          Length = 850

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP G+ G+ CE + D+C     C N   CVD +NNY C C    YTG  C+  ++ C 
Sbjct: 409 CSCPLGFEGQRCEINPDDCED-NDCENNATCVDGINNYVCIC-PPNYTGELCDEVIDHCV 466

Query: 437 EDRALCGH-GVCYDTYGGFVCACQPATPG 520
            +  LC H   C     GF C C P   G
Sbjct: 467 PELNLCQHEAKCIPLDKGFSCECVPGYSG 495



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +C CPP YTG  C+  +D C      C +  +C+     ++C+C   GY+G  CET+ ++
Sbjct: 446 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCEC-VPGYSGKLCETDNDD 504

Query: 431 CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
           C   +  C HG  C DT  G+ C C     G
Sbjct: 505 CVAHK--CRHGAQCVDTINGYTCTCPQGFSG 533



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 29/67 (43%), Positives = 40/67 (59%)
 Frame = +2

Query: 215 QRQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATG 394
           Q + +  P  +   C C PGY+G+ CETD D+C  A  C +G +CVD +N YTC C   G
Sbjct: 473 QHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV-AHKCRHGAQCVDTINGYTCTC-PQG 530

Query: 395 YTGARCE 415
           ++G  CE
Sbjct: 531 FSGPFCE 537



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 25/55 (45%), Positives = 33/55 (60%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   Y+G  CE D  D C +  CRHGA+CV+   G Y+C CP G+ G +CE
Sbjct: 485 FSCECVPGYSGKLCETD-NDDCVAHKCRHGAQCVDTING-YTCTCPQGFSGPFCE 537



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 39/82 (47%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   +TG  C+ +A DPC    C HG +CV  G   Y C C  GY G  C+ +     
Sbjct: 680 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGT-SYMCKCAEGYGGDLCDNKNDSAN 737

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
            C A  C ++G C +   G+ Y
Sbjct: 738 ACSAFKC-HHGQCHISDQGEPY 758



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           Y C C   YTG  C+ +  D C      C+H A+C+   +G +SC+C PGY G  CE + 
Sbjct: 445 YVCICPPNYTGELCD-EVIDHCVPELNLCQHEAKCIPLDKG-FSCECVPGYSGKLCETD- 501

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
             +  CVA  CR+   C     G T + P
Sbjct: 502 --NDDCVAHKCRHGAQCVDTINGYTCTCP 528



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC--VDA-VNNYTCDCTATGYTGARCETNVN 427
           C CP  Y G++C   ++ C     C +GG C   D+  + ++C C   G+ G RCE N +
Sbjct: 368 CACPYSYKGKDCTVPINTCI-QNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRCEINPD 425

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +C ED     +  C D    +VC C P   G
Sbjct: 426 DC-EDNDCENNATCVDGINNYVCICPPNYTG 455



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 224 LQRAPRRRHLLCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
           L R+  +  ++C C PG+TG  C+ +  D C G     + G+CV    +Y C C A GY 
Sbjct: 669 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC--HHGKCVATGTSYMCKC-AEGYG 725

Query: 401 GARCETNVNECEEDRAL-CGHGVCY-DTYGGFVCACQPATPG 520
           G  C+   +      A  C HG C+    G   C CQP   G
Sbjct: 726 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 767



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
           Y C C   Y G +C V   + C    C+HG  C + D   D +SC CP G+ G  CE+  
Sbjct: 366 YRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINP 424

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C    C NN +C
Sbjct: 425 D-D--CEDNDCENNATC 438



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           + C C   + G  CE++  D C    C + A CV DG  +Y C CPP Y G  C+
Sbjct: 407 FSCSCPLGFEGQRCEINPDD-CEDNDCENNATCV-DGINNYVCICPPNYTGELCD 459



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEV--DAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C   Y G+ C+   D+ + C++  C HG +C    +G+  C C PG+ G +C+ E
Sbjct: 716 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE 773



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C S+ C++   C +D    Y C CP  Y G  C + ++    C+  PC++ G+C
Sbjct: 347 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN---TCIQNPCQHGGTC 397



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 66  CASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C S   C+HG  C    +    C+C PG+ G  C+ E + DP C+   C ++G C
Sbjct: 659 CKSCTVCKHGL-CRSVEKDSVVCECRPGWTGPLCDQE-ARDP-CLGHRC-HHGKC 709


>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
          Length = 1523

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G+ CE + D+C     C N   CVD +NNY C C    YTG  C+  ++ C 
Sbjct: 982  CSCPLGFEGQRCEINPDDCED-NDCENNATCVDGINNYVCIC-PPNYTGELCDEVIDHCV 1039

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             +  LC H   C     GF C C P   G
Sbjct: 1040 PELNLCQHEAKCIPLDKGFSCECVPGYSG 1068



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            +C CPP YTG  C+  +D C      C +  +C+     ++C+C   GY+G  CET+ ++
Sbjct: 1019 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCEC-VPGYSGKLCETDNDD 1077

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C   +  C HG  C DT  G+ C C     G
Sbjct: 1078 CVAHK--CRHGAQCVDTINGYTCTCPQGFSG 1106



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 29/67 (43%), Positives = 40/67 (59%)
 Frame = +2

Query: 215  QRQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATG 394
            Q + +  P  +   C C PGY+G+ CETD D+C  A  C +G +CVD +N YTC C   G
Sbjct: 1046 QHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV-AHKCRHGAQCVDTINGYTCTC-PQG 1103

Query: 395  YTGARCE 415
            ++G  CE
Sbjct: 1104 FSGPFCE 1110



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y+G  CE D  D C +  CRHGA+CV+   G Y+C CP G+ G +CE    +
Sbjct: 1058 FSCECVPGYSGKLCETD-NDDCVAHKCRHGAQCVDTING-YTCTCPQGFSGPFCEHPPPM 1115

Query: 183  DPL----CVAGPCRNNGSCSVPPGGDTYSAP 263
              L    C    C+N   C V     T   P
Sbjct: 1116 VLLQTSPCDQYECQNGAQCIVVQQEPTCRCP 1146



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 39/82 (47%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C+ +A DPC    C HG +CV  G   Y C C  GY G  C+ +     
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGT-SYMCKCAEGYGGDLCDNKNDSAN 1410

Query: 189  LCVAGPCRNNGSCSVPPGGDTY 254
             C A  C ++G C +   G+ Y
Sbjct: 1411 ACSAFKC-HHGQCHISDQGEPY 1431



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  C+ +  D C      C+H A+C+   +G +SC+C PGY G  CE + 
Sbjct: 1018 YVCICPPNYTGELCD-EVIDHCVPELNLCQHEAKCIPLDKG-FSCECVPGYSGKLCETD- 1074

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              +  CVA  CR+   C     G T + P
Sbjct: 1075 --NDDCVAHKCRHGAQCVDTINGYTCTCP 1101



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC--VDA-VNNYTCDCTATGYTGARCETNVN 427
            C CP  Y G++C   ++ C     C +GG C   D+  + ++C C   G+ G RCE N +
Sbjct: 941  CACPYSYKGKDCTVPINTCI-QNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRCEINPD 998

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    +VC C P   G
Sbjct: 999  DC-EDNDCENNATCVDGINNYVCICPPNYTG 1028



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
            L R+  +  ++C C PG+TG  C+ +  D C G     + G+CV    +Y C C A GY 
Sbjct: 1342 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC--HHGKCVATGTSYMCKC-AEGYG 1398

Query: 401  GARCETNVNECEEDRAL-CGHGVCY-DTYGGFVCACQPATPG 520
            G  C+   +      A  C HG C+    G   C CQP   G
Sbjct: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   Y G +C V   + C    C+HG  C + D   D +SC CP G+ G  CE+  
Sbjct: 939  YRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINP 997

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 998  D-D--CEDNDCENNATC 1011



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            + C C   + G  CE++  D C    C + A CV DG  +Y C CPP Y G  C+
Sbjct: 980  FSCSCPLGFEGQRCEINPDD-CEDNDCENNATCV-DGINNYVCICPPNYTGELCD 1032



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEV--DAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y G+ C+   D+ + C++  C HG +C    +G+  C C PG+ G +C+ E
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE 1446



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S+ C++   C +D    Y C CP  Y G  C + ++    C+  PC++ G+C
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN---TCIQNPCQHGGTC 970



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   ++G  CE      +    PC    C++GA+C+   + + +C CPPG+ G  C
Sbjct: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQ-EPTCRCPPGFAGPRC 1154

Query: 165  ELEVSLD 185
            E  ++++
Sbjct: 1155 EKLITVN 1161



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-------TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            CTCP G++G  CE            C     C NG +C+      TC C   G+ G RCE
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCD-QYECQNGAQCIVVQQEPTCRC-PPGFAGPRCE 1155



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 66   CASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S   C+HG  C    +    C+C PG+ G  C+ E + DP C+   C ++G C
Sbjct: 1332 CKSCTVCKHGL-CRSVEKDSVVCECRPGWTGPLCDQE-ARDP-CLGHRC-HHGKC 1382


>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
          Length = 1559

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+CP G+ G+ CE + D+C     C N   CVD +NNY C C    YTG  C+  ++ C 
Sbjct: 1018 CSCPLGFEGQRCEINPDDCED-NDCENNATCVDGINNYVCIC-PPNYTGELCDEVIDHCV 1075

Query: 437  EDRALCGH-GVCYDTYGGFVCACQPATPG 520
             +  LC H   C     GF C C P   G
Sbjct: 1076 PELNLCQHEAKCIPLDKGFSCECVPGYSG 1104



 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            +C CPP YTG  C+  +D C      C +  +C+     ++C+C   GY+G  CET+ ++
Sbjct: 1055 VCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCEC-VPGYSGKLCETDNDD 1113

Query: 431  CEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
            C   +  C HG  C DT  G+ C C     G
Sbjct: 1114 CVAHK--CRHGAQCVDTINGYTCTCPQGFSG 1142



 Score = 67.3 bits (157), Expect = 4e-11
 Identities = 29/67 (43%), Positives = 40/67 (59%)
 Frame = +2

Query: 215  QRQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATG 394
            Q + +  P  +   C C PGY+G+ CETD D+C  A  C +G +CVD +N YTC C   G
Sbjct: 1082 QHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCV-AHKCRHGAQCVDTINGYTCTC-PQG 1139

Query: 395  YTGARCE 415
            ++G  CE
Sbjct: 1140 FSGPFCE 1146



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            + C C   Y+G  CE D  D C +  CRHGA+CV+   G Y+C CP G+ G +CE    +
Sbjct: 1094 FSCECVPGYSGKLCETD-NDDCVAHKCRHGAQCVDTING-YTCTCPQGFSGPFCEHPPPM 1151

Query: 183  DPL----CVAGPCRNNGSCSVPPGGDTYSAP 263
              L    C    C+N   C V     T   P
Sbjct: 1152 VLLQTSPCDQYECQNGAQCIVVQQEPTCRCP 1182



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 39/82 (47%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C+ +A DPC    C HG +CV  G   Y C C  GY G  C+ +     
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGT-SYMCKCAEGYGGDLCDNKNDSAN 1446

Query: 189  LCVAGPCRNNGSCSVPPGGDTY 254
             C A  C ++G C +   G+ Y
Sbjct: 1447 ACSAFKC-HHGQCHISDQGEPY 1467



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            Y C C   YTG  C+ +  D C      C+H A+C+   +G +SC+C PGY G  CE + 
Sbjct: 1054 YVCICPPNYTGELCD-EVIDHCVPELNLCQHEAKCIPLDKG-FSCECVPGYSGKLCETD- 1110

Query: 177  SLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              +  CVA  CR+   C     G T + P
Sbjct: 1111 --NDDCVAHKCRHGAQCVDTINGYTCTCP 1137



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC--VDA-VNNYTCDCTATGYTGARCETNVN 427
            C CP  Y G++C   ++ C     C +GG C   D+  + ++C C   G+ G RCE N +
Sbjct: 977  CACPYSYKGKDCTVPINTCI-QNPCQHGGTCHLSDSHKDGFSCSC-PLGFEGQRCEINPD 1034

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            +C ED     +  C D    +VC C P   G
Sbjct: 1035 DC-EDNDCENNATCVDGINNYVCICPPNYTG 1064



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 224  LQRAPRRRHLLCTCPPGYTGRNCETDV-DECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
            L R+  +  ++C C PG+TG  C+ +  D C G     + G+CV    +Y C C A GY 
Sbjct: 1378 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC--HHGKCVATGTSYMCKC-AEGYG 1434

Query: 401  GARCETNVNECEEDRAL-CGHGVCY-DTYGGFVCACQPATPG 520
            G  C+   +      A  C HG C+    G   C CQP   G
Sbjct: 1435 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1476



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARC-VEDGRGD-YSCDCPPGYHGTYCELEV 176
            Y C C   Y G +C V   + C    C+HG  C + D   D +SC CP G+ G  CE+  
Sbjct: 975  YRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINP 1033

Query: 177  SLDPLCVAGPCRNNGSC 227
              D  C    C NN +C
Sbjct: 1034 D-D--CEDNDCENNATC 1047



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 28/55 (50%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            + C C   + G  CE++  D C    C + A CV DG  +Y C CPP Y G  C+
Sbjct: 1016 FSCSCPLGFEGQRCEINPDD-CEDNDCENNATCV-DGINNYVCICPPNYTGELCD 1068



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEV--DAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C   Y G+ C+   D+ + C++  C HG +C    +G+  C C PG+ G +C+ E
Sbjct: 1425 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQE 1482



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 17/54 (31%), Positives = 28/54 (51%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S+ C++   C +D    Y C CP  Y G  C + ++    C+  PC++ G+C
Sbjct: 956  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN---TCIQNPCQHGGTC 1006



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
 Frame = +3

Query: 3    YECHCTARYTGNNCE------VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
            Y C C   ++G  CE      +    PC    C++GA+C+   + + +C CPPG+ G  C
Sbjct: 1132 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQ-EPTCRCPPGFAGPRC 1190

Query: 165  ELEVSLD 185
            E  ++++
Sbjct: 1191 EKLITVN 1197



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-------TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            CTCP G++G  CE            C     C NG +C+      TC C   G+ G RCE
Sbjct: 1134 CTCPQGFSGPFCEHPPPMVLLQTSPCD-QYECQNGAQCIVVQQEPTCRC-PPGFAGPRCE 1191



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
 Frame = +3

Query: 66   CASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            C S   C+HG  C    +    C+C PG+ G  C+ E + DP C+   C ++G C
Sbjct: 1368 CKSCTVCKHGL-CRSVEKDSVVCECRPGWTGPLCDQE-ARDP-CLGHRC-HHGKC 1418


>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
           protein.
          Length = 1095

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 47/87 (54%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y CHC   + G+ C+ D  +PC S  C++GA C+    G Y C C PGY G  C  E+  
Sbjct: 6   YFCHCPPGFQGSLCQ-DHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDA 63

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC N+G+C+  PGG   + P
Sbjct: 64  ---CQSQPCHNHGTCTPKPGGFHCACP 87



 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 34/93 (36%), Positives = 44/93 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C CPPG+ G  C+  V+ C  +  C NG  C+   + Y C C A GY G  C   ++ C+
Sbjct: 8   CHCPPGFQGSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQC-APGYDGQNCSKELDACQ 65

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGSTATG 535
             +    HG C    GGF CAC P   G    G
Sbjct: 66  S-QPCHNHGTCTPKPGGFHCACPPGFVGLRCEG 97



 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           LC C PGY G+NC  ++D C  +  C N G C      + C C   G+ G RCE +V+EC
Sbjct: 45  LCQCAPGYDGQNCSKELDACQ-SQPCHNHGTCTPKPGGFHCAC-PPGFVGLRCEGDVDEC 102

Query: 434 -EEDRALCGHGVCYDTYGGFVCACQPATPG 520
            ++     G   C+     F C C P   G
Sbjct: 103 LDQPCHPTGTAACHSLANAFYCQCLPGHTG 132



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CPPG+ G  CE DVDEC        G   C    N + C C   G+TG  CE  ++ C
Sbjct: 84  CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC-LPGHTGQWCEVEIDPC 142

Query: 434 EEDRALCGHGVCYDTYG---GFVCACQPATPGSTAT 532
                  G G C  T G   GF+C C     G T +
Sbjct: 143 HSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCS 177



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/76 (34%), Positives = 34/76 (44%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y G NC  +  D C S  C +   C     G + C CPPG+ G  CE +V  
Sbjct: 44  YLCQCAPGYDGQNCSKEL-DACQSQPCHNHGTCTPKP-GGFHCACPPGFVGLRCEGDVD- 100

Query: 183 DPLCVAGPCRNNGSCS 230
              C+  PC   G+ +
Sbjct: 101 --ECLDQPCHPTGTAA 114



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           + C C   + G  CE D  D C    C   G          + C C PG+ G +CE+E+ 
Sbjct: 82  FHCACPPGFVGLRCEGDV-DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI- 139

Query: 180 LDPLCVAGPCRNNGSCSVPPG 242
            DP C + PC + G+C    G
Sbjct: 140 -DP-CHSQPCFHGGTCEATAG 158



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 2/80 (2%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYS--CDCPPGYHGTYCELEVSL 182
           CHC   + G  C   A   C    C HG  C+   +  +   C C  GY G  C    + 
Sbjct: 165 CHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 223

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
                  PC  NGSCS   G
Sbjct: 224 KGCGPPSPCLYNGSCSETTG 243



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +3

Query: 108 DGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
           D    Y C CPPG+ G+ C+  V  +P C + PC+N  +C   P G
Sbjct: 1   DSGPSYFCHCPPGFQGSLCQDHV--NP-CESRPCQNGATCMAQPSG 43



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVN-NYTCDCTA-TGYTGARCET--N 421
           +C CP G+ G  C      C G   C +GG C+ +    +   C   +GY G  C T   
Sbjct: 164 ICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 222

Query: 422 VNECEEDRALCGHGVCYDTYG----GFVCACQPATPG 520
              C        +G C +T G    GF C+C  ++PG
Sbjct: 223 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPG 259


>BC035009-1|AAH35009.1|  737|Homo sapiens delta/notch-like EGF
           repeat containing protein.
          Length = 737

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+ G  C+++++ 
Sbjct: 527 YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDIN- 583

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC + GSC   P G     P
Sbjct: 584 --ECDSNPCHHGGSCLDQPNGYNCHCP 608



 Score = 72.9 bits (171), Expect = 9e-13
 Identities = 33/90 (36%), Positives = 44/90 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C++ +D C     C NG  C+ +++ +TC C   GY G+ CE  V+ C 
Sbjct: 378 CVCLPGYTGELCQSKIDYCI-LDPCRNGATCISSLSGFTCQC-PEGYFGSACEEKVDLCA 435

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
                  +G CY     F C C P   G T
Sbjct: 436 SSPCQ-NNGTCYVDGVHFTCNCSPGFTGPT 464



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 32/77 (41%), Positives = 43/77 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG  C+    D C    CR+GA C+    G ++C CP GY G+ CE +V  
Sbjct: 376 FTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKVD- 432

Query: 183 DPLCVAGPCRNNGSCSV 233
             LC + PC+NNG+C V
Sbjct: 433 --LCASSPCQNNGTCYV 447



 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP GY G  CE  VD C+ ++ C N G C VD V ++TC+C + G+TG  C   ++ C
Sbjct: 416 CQCPEGYFGSACEEKVDLCA-SSPCQNNGTCYVDGV-HFTCNC-SPGFTGPTCAQLIDFC 472

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
               + C HG C      + C C P   G
Sbjct: 473 A--LSPCAHGTCRSVGTSYKCLCDPGYHG 499



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   Y G +CE   D C+  + CLNG  C     N TC C A G+TG  C+ ++NEC+
Sbjct: 529 CVCLAEYKGTHCELYKDPCANVS-CLNGATCDSDGLNGTCIC-APGFTGEECDIDINECD 586

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
            +   C H G C D   G+ C C
Sbjct: 587 SNP--CHHGGSCLDQPNGYNCHC 607



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/88 (39%), Positives = 39/88 (44%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 491 CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 548

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G     D   G  C C P   G
Sbjct: 549 NVSCLNGATCDSDGLNG-TCICAPGFTG 575



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 24/56 (42%), Positives = 34/56 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C C PG+TG  C+ D++EC  +  C +GG C+D  N Y C C   G+ GA CE ++
Sbjct: 567 CICAPGFTGEECDIDINECD-SNPCHHGGSCLDQPNGYNCHC-PHGWVGANCEIHL 620



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C+  +TG  C     D CA + C HG  C   G   Y C C PGYHG YCE E + 
Sbjct: 452 FTCNCSPGFTGPTC-AQLIDFCALSPCAHGT-CRSVGTS-YKCLCDPGYHGLYCEEEYN- 507

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC N  +C
Sbjct: 508 --ECLSAPCLNAATC 520



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 37/85 (43%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C PG+TG  C   +D C+  + C + G C     +Y C C   GY G  CE   N
Sbjct: 451 HFTCNCSPGFTGPTCAQLIDFCA-LSPCAH-GTCRSVGTSYKCLCD-PGYHGLYCEEEYN 507

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC     L     C D   G+ C C
Sbjct: 508 ECLSAPCL-NAATCRDLVNGYECVC 531



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-----VNNYTCDCTATGYT 400
           P      CTC   Y G  CE + D C     C N   C+DA      +N+TC C   GYT
Sbjct: 329 PSEATFSCTCEEQYVGTFCE-EYDACQ-RKPCQNNASCIDANEKQDGSNFTCVC-LPGYT 385

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           G  C++ ++ C  D    G   C  +  GF C C     GS
Sbjct: 386 GELCQSKIDYCILDPCRNG-ATCISSLSGFTCQCPEGYFGS 425



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-----DGRGDYSCDCPPGYHGTYCE 167
           + C C  +Y G  CE    D C    C++ A C++     DG  +++C C PGY G  C+
Sbjct: 334 FSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDG-SNFTCVCLPGYTGELCQ 390

Query: 168 LEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            ++     C+  PCRN  +C     G T   P
Sbjct: 391 SKID---YCILDPCRNGATCISSLSGFTCQCP 419



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   +TG  C++D  + C S  C HG  C++   G Y+C CP G+ G  CE+ +
Sbjct: 567 CICAPGFTGEECDIDINE-CDSNPCHHGGSCLDQPNG-YNCHCPHGWVGANCEIHL 620



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGYHGTYCE 167
           Y C C A  +G NC++ A DPCAS  C HG  +         Y C C  GY G  CE
Sbjct: 78  YSCTCPAGISGANCQLVA-DPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
 Frame = +3

Query: 48  VDAGDPCASAACRHGARCVE-----------DGRGDYSCDCPPGYHGTYCELEVSLDPLC 194
           + A  PCA+  CR+G  C              G   YSC CP G  G  C+L    DP C
Sbjct: 42  LSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVA--DP-C 98

Query: 195 VAGPCRNNGSCS 230
            + PC ++G+CS
Sbjct: 99  ASNPC-HHGNCS 109



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNG---GRCVDAVNNYTCDCTATGYTGARCE 415
           CTCP G +G NC+   D C+ +  C +G        + + Y C C   GY G  CE
Sbjct: 80  CTCPAGISGANCQLVADPCA-SNPCHHGNCSSSSSSSSDGYLCICN-EGYEGPNCE 133



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +3

Query: 81  CRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C    +C  +     +SC C   Y GT+CE     D  C   PC+NN SC
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYD-ACQRKPCQNNASC 364


>BC024766-1|AAH24766.2|  454|Homo sapiens DNER protein protein.
          Length = 454

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+ G  C+++++ 
Sbjct: 244 YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDIN- 300

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC + GSC   P G     P
Sbjct: 301 --ECDSNPCHHGGSCLDQPNGYNCHCP 325



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 33/90 (36%), Positives = 44/90 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C++ +D C     C NG  C+ +++ +TC C   GY G+ CE  V+ C 
Sbjct: 95  CVCLPGYTGELCQSKIDYCI-LDPCRNGATCISSLSGFTCQC-PEGYFGSACEEKVDPCA 152

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
                  +G CY     F C C P   G T
Sbjct: 153 SSPCQ-NNGTCYVDGVHFTCNCSPGFTGPT 181



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/77 (42%), Positives = 44/77 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG  C+    D C    CR+GA C+    G ++C CP GY G+ CE +V  
Sbjct: 93  FTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKV-- 148

Query: 183 DPLCVAGPCRNNGSCSV 233
           DP C + PC+NNG+C V
Sbjct: 149 DP-CASSPCQNNGTCYV 164



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP GY G  CE  VD C+ ++ C N G C VD V ++TC+C + G+TG  C   ++ C
Sbjct: 133 CQCPEGYFGSACEEKVDPCA-SSPCQNNGTCYVDGV-HFTCNC-SPGFTGPTCAQLIDFC 189

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
               + C HG C      + C C P   G
Sbjct: 190 A--LSPCAHGTCRSVGTSYKCLCDPGYHG 216



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   Y G +CE   D C+  + CLNG  C     N TC C A G+TG  C+ ++NEC+
Sbjct: 246 CVCLAEYKGTHCELYKDPCANVS-CLNGATCDSDGLNGTCIC-APGFTGEECDIDINECD 303

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
            +   C H G C D   G+ C C
Sbjct: 304 SNP--CHHGGSCLDQPNGYNCHC 324



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/88 (39%), Positives = 39/88 (44%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 208 CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 265

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G     D   G  C C P   G
Sbjct: 266 NVSCLNGATCDSDGLNG-TCICAPGFTG 292



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 24/56 (42%), Positives = 34/56 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C C PG+TG  C+ D++EC  +  C +GG C+D  N Y C C   G+ GA CE ++
Sbjct: 284 CICAPGFTGEECDIDINECD-SNPCHHGGSCLDQPNGYNCHC-PHGWVGANCEIHL 337



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C+  +TG  C     D CA + C HG  C   G   Y C C PGYHG YCE E + 
Sbjct: 169 FTCNCSPGFTGPTC-AQLIDFCALSPCAHGT-CRSVGTS-YKCLCDPGYHGLYCEEEYN- 224

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC N  +C
Sbjct: 225 --ECLSAPCLNAATC 237



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G+ CE +  DPCAS+ C++   C  DG   ++C+C PG+ G  C   +  
Sbjct: 131 FTCQCPEGYFGSACE-EKVDPCASSPCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDF 188

Query: 183 DPL--CVAGPCRNNGS---CSVPPG 242
             L  C  G CR+ G+   C   PG
Sbjct: 189 CALSPCAHGTCRSVGTSYKCLCDPG 213



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 37/85 (43%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C PG+TG  C   +D C+  + C + G C     +Y C C   GY G  CE   N
Sbjct: 168 HFTCNCSPGFTGPTCAQLIDFCA-LSPCAH-GTCRSVGTSYKCLCD-PGYHGLYCEEEYN 224

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC     L     C D   G+ C C
Sbjct: 225 ECLSAPCL-NAATCRDLVNGYECVC 248



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-----VNNYTCDCTATGYT 400
           P      CTC   Y G  CE + D C     C N   C+DA      +N+TC C   GYT
Sbjct: 46  PSEATFSCTCEEQYVGTFCE-EYDACQ-RKPCQNNASCIDANEKQDGSNFTCVC-LPGYT 102

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           G  C++ ++ C  D    G   C  +  GF C C     GS
Sbjct: 103 GELCQSKIDYCILDPCRNG-ATCISSLSGFTCQCPEGYFGS 142



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-----DGRGDYSCDCPPGYHGTYCE 167
           + C C  +Y G  CE    D C    C++ A C++     DG  +++C C PGY G  C+
Sbjct: 51  FSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDG-SNFTCVCLPGYTGELCQ 107

Query: 168 LEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            ++     C+  PCRN  +C     G T   P
Sbjct: 108 SKID---YCILDPCRNGATCISSLSGFTCQCP 136



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   +TG  C++D  + C S  C HG  C++   G Y+C CP G+ G  CE+ +
Sbjct: 284 CICAPGFTGEECDIDINE-CDSNPCHHGGSCLDQPNG-YNCHCPHGWVGANCEIHL 337



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +3

Query: 81  CRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C    +C  +     +SC C   Y GT+CE     D  C   PC+NN SC
Sbjct: 36  CSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYD-ACQRKPCQNNASC 81


>AY358891-1|AAQ89250.1|  737|Homo sapiens QPRR262 protein.
          Length = 737

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+ G  C+++++ 
Sbjct: 527 YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDIN- 583

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC + GSC   P G     P
Sbjct: 584 --ECDSNPCHHGGSCLDQPNGYNCHCP 608



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 33/90 (36%), Positives = 44/90 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C++ +D C     C NG  C+ +++ +TC C   GY G+ CE  V+ C 
Sbjct: 378 CVCLPGYTGELCQSKIDYCI-LDPCRNGATCISSLSGFTCQC-PEGYFGSACEEKVDPCA 435

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
                  +G CY     F C C P   G T
Sbjct: 436 SSPCQ-NNGTCYVDGVHFTCNCSPGFTGPT 464



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/77 (42%), Positives = 44/77 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG  C+    D C    CR+GA C+    G ++C CP GY G+ CE +V  
Sbjct: 376 FTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKV-- 431

Query: 183 DPLCVAGPCRNNGSCSV 233
           DP C + PC+NNG+C V
Sbjct: 432 DP-CASSPCQNNGTCYV 447



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP GY G  CE  VD C+ ++ C N G C VD V ++TC+C + G+TG  C   ++ C
Sbjct: 416 CQCPEGYFGSACEEKVDPCA-SSPCQNNGTCYVDGV-HFTCNC-SPGFTGPTCAQLIDFC 472

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
               + C HG C      + C C P   G
Sbjct: 473 A--LSPCAHGTCRSVGTSYKCLCDPGYHG 499



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   Y G +CE   D C+  + CLNG  C     N TC C A G+TG  C+ ++NEC+
Sbjct: 529 CVCLAEYKGTHCELYKDPCANVS-CLNGATCDSDGLNGTCIC-APGFTGEECDIDINECD 586

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
            +   C H G C D   G+ C C
Sbjct: 587 SNP--CHHGGSCLDQPNGYNCHC 607



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/88 (39%), Positives = 39/88 (44%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 491 CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 548

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G     D   G  C C P   G
Sbjct: 549 NVSCLNGATCDSDGLNG-TCICAPGFTG 575



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 24/56 (42%), Positives = 34/56 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C C PG+TG  C+ D++EC  +  C +GG C+D  N Y C C   G+ GA CE ++
Sbjct: 567 CICAPGFTGEECDIDINECD-SNPCHHGGSCLDQPNGYNCHC-PHGWVGANCEIHL 620



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C+  +TG  C     D CA + C HG  C   G   Y C C PGYHG YCE E + 
Sbjct: 452 FTCNCSPGFTGPTC-AQLIDFCALSPCAHGT-CRSVGTS-YKCLCDPGYHGLYCEEEYN- 507

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC N  +C
Sbjct: 508 --ECLSAPCLNAATC 520



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G+ CE +  DPCAS+ C++   C  DG   ++C+C PG+ G  C   +  
Sbjct: 414 FTCQCPEGYFGSACE-EKVDPCASSPCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDF 471

Query: 183 DPL--CVAGPCRNNGS---CSVPPG 242
             L  C  G CR+ G+   C   PG
Sbjct: 472 CALSPCAHGTCRSVGTSYKCLCDPG 496



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 37/85 (43%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C PG+TG  C   +D C+  + C + G C     +Y C C   GY G  CE   N
Sbjct: 451 HFTCNCSPGFTGPTCAQLIDFCA-LSPCAH-GTCRSVGTSYKCLCD-PGYHGLYCEEEYN 507

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC     L     C D   G+ C C
Sbjct: 508 ECLSAPCL-NAATCRDLVNGYECVC 531



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-----VNNYTCDCTATGYT 400
           P      CTC   Y G  CE + D C     C N   C+DA      +N+TC C   GYT
Sbjct: 329 PSEATFSCTCEEQYVGTFCE-EYDACQ-RKPCQNNASCIDANEKQDGSNFTCVC-LPGYT 385

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           G  C++ ++ C  D    G   C  +  GF C C     GS
Sbjct: 386 GELCQSKIDYCILDPCRNG-ATCISSLSGFTCQCPEGYFGS 425



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-----DGRGDYSCDCPPGYHGTYCE 167
           + C C  +Y G  CE    D C    C++ A C++     DG  +++C C PGY G  C+
Sbjct: 334 FSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDG-SNFTCVCLPGYTGELCQ 390

Query: 168 LEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            ++     C+  PCRN  +C     G T   P
Sbjct: 391 SKID---YCILDPCRNGATCISSLSGFTCQCP 419



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   +TG  C++D  + C S  C HG  C++   G Y+C CP G+ G  CE+ +
Sbjct: 567 CICAPGFTGEECDIDINE-CDSNPCHHGGSCLDQPNG-YNCHCPHGWVGANCEIHL 620



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGYHGTYCE 167
           Y C C A  +G NC++ A DPCAS  C HG  +         Y C C  GY G  CE
Sbjct: 78  YSCTCPAGISGANCQLVA-DPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
 Frame = +3

Query: 48  VDAGDPCASAACRHGARCVE-----------DGRGDYSCDCPPGYHGTYCELEVSLDPLC 194
           + A  PCA+  CR+G  C              G   YSC CP G  G  C+L    DP C
Sbjct: 42  LSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVA--DP-C 98

Query: 195 VAGPCRNNGSCS 230
            + PC ++G+CS
Sbjct: 99  ASNPC-HHGNCS 109



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNG---GRCVDAVNNYTCDCTATGYTGARCE 415
           CTCP G +G NC+   D C+ +  C +G        + + Y C C   GY G  CE
Sbjct: 80  CTCPAGISGANCQLVADPCA-SNPCHHGNCSSSSSSSSDGYLCICN-EGYEGPNCE 133



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +3

Query: 81  CRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C    +C  +     +SC C   Y GT+CE     D  C   PC+NN SC
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYD-ACQRKPCQNNASC 364


>AL137311-1|CAB70690.1|  252|Homo sapiens hypothetical protein
           protein.
          Length = 252

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+ G  C+++++ 
Sbjct: 42  YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDIN- 98

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC + GSC   P G     P
Sbjct: 99  --ECDSNPCHHGGSCLDQPNGYNCHCP 123



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   Y G +CE   D C+  + CLNG  C     N TC C A G+TG  C+ ++NEC+
Sbjct: 44  CVCLAEYKGTHCELYKDPCANVS-CLNGATCDSDGLNGTCIC-APGFTGEECDIDINECD 101

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
            +   C H G C D   G+ C C
Sbjct: 102 SNP--CHHGGSCLDQPNGYNCHC 122



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/88 (39%), Positives = 39/88 (44%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 6   CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 63

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G     D   G  C C P   G
Sbjct: 64  NVSCLNGATCDSDGLNG-TCICAPGFTG 90



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 24/56 (42%), Positives = 34/56 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C C PG+TG  C+ D++EC  +  C +GG C+D  N Y C C   G+ GA CE ++
Sbjct: 82  CICAPGFTGEECDIDINECD-SNPCHHGGSCLDQPNGYNCHC-PHGWVGANCEIHL 135



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   +TG  C++D  + C S  C HG  C++   G Y+C CP G+ G  CE+ +
Sbjct: 82  CICAPGFTGEECDIDINE-CDSNPCHHGGSCLDQPNG-YNCHCPHGWVGANCEIHL 135



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +3

Query: 123 YSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           Y C C PGYHG YCE E +    C++ PC N  +C
Sbjct: 4   YKCLCDPGYHGLYCEEEYN---ECLSAPCLNAATC 35


>AF442487-1|AAM21557.1|  737|Homo sapiens delta-notch-like EGF
           repeat-containing transmembrane protein protein.
          Length = 737

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 34/87 (39%), Positives = 48/87 (55%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+ G  C+++++ 
Sbjct: 527 YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDIN- 583

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAP 263
              C + PC + GSC   P G     P
Sbjct: 584 --ECDSNPCHHGGSCLDQPNGYNCHCP 608



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 33/90 (36%), Positives = 44/90 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C++ +D C     C NG  C+ +++ +TC C   GY G+ CE  V+ C 
Sbjct: 378 CVCLPGYTGELCQSKIDYCI-LDPCRNGATCISSLSGFTCQC-PEGYFGSACEEKVDPCA 435

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
                  +G CY     F C C P   G T
Sbjct: 436 SSPCQ-NNGTCYVDGVHFTCNCSPGFTGPT 464



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/77 (42%), Positives = 44/77 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG  C+    D C    CR+GA C+    G ++C CP GY G+ CE +V  
Sbjct: 376 FTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKV-- 431

Query: 183 DPLCVAGPCRNNGSCSV 233
           DP C + PC+NNG+C V
Sbjct: 432 DP-CASSPCQNNGTCYV 447



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP GY G  CE  VD C+ ++ C N G C VD V ++TC+C + G+TG  C   ++ C
Sbjct: 416 CQCPEGYFGSACEEKVDPCA-SSPCQNNGTCYVDGV-HFTCNC-SPGFTGPTCAQLIDFC 472

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
               + C HG C      + C C P   G
Sbjct: 473 A--LSPCAHGTCRSVGTSYKCLCDPGYHG 499



 Score = 66.5 bits (155), Expect = 7e-11
 Identities = 33/83 (39%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   Y G +CE   D C+  + CLNG  C     N TC C A G+TG  C+ ++NEC+
Sbjct: 529 CVCLAEYKGTHCELYKDPCANVS-CLNGATCDSDGLNGTCIC-APGFTGEECDIDINECD 586

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
            +   C H G C D   G+ C C
Sbjct: 587 SNP--CHHGGSCLDQPNGYNCHC 607



 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/88 (39%), Positives = 39/88 (44%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 491 CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 548

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
               L G     D   G  C C P   G
Sbjct: 549 NVSCLNGATCDSDGLNG-TCICAPGFTG 575



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 24/56 (42%), Positives = 34/56 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C C PG+TG  C+ D++EC  +  C +GG C+D  N Y C C   G+ GA CE ++
Sbjct: 567 CICAPGFTGEECDIDINECD-SNPCHHGGSCLDQPNGYNCHC-PHGWVGANCEIHL 620



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C+  +TG  C     D CA + C HG  C   G   Y C C PGYHG YCE E + 
Sbjct: 452 FTCNCSPGFTGPTC-AQLIDFCALSPCAHGT-CRSVGTS-YKCLCDPGYHGLYCEEEYN- 507

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC N  +C
Sbjct: 508 --ECLSAPCLNAATC 520



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G+ CE +  DPCAS+ C++   C  DG   ++C+C PG+ G  C   +  
Sbjct: 414 FTCQCPEGYFGSACE-EKVDPCASSPCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDF 471

Query: 183 DPL--CVAGPCRNNGS---CSVPPG 242
             L  C  G CR+ G+   C   PG
Sbjct: 472 CALSPCAHGTCRSVGTSYKCLCDPG 496



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 37/85 (43%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C PG+TG  C   +D C+  + C + G C     +Y C C   GY G  CE   N
Sbjct: 451 HFTCNCSPGFTGPTCAQLIDFCA-LSPCAH-GTCRSVGTSYKCLCD-PGYHGLYCEEEYN 507

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC     L     C D   G+ C C
Sbjct: 508 ECLSAPCL-NAATCRDLVNGYECVC 531



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-----VNNYTCDCTATGYT 400
           P      CTC   Y G  CE + D C     C N   C+DA      +N+TC C   GYT
Sbjct: 329 PSEATFSCTCEEQYVGTFCE-EYDACQ-RKPCQNNASCIDANEKQDGSNFTCVC-LPGYT 385

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           G  C++ ++ C  D    G   C  +  GF C C     GS
Sbjct: 386 GELCQSKIDYCILDPCRNG-ATCISSLSGFTCQCPEGYFGS 425



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-----DGRGDYSCDCPPGYHGTYCE 167
           + C C  +Y G  CE    D C    C++ A C++     DG  +++C C PGY G  C+
Sbjct: 334 FSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDG-SNFTCVCLPGYTGELCQ 390

Query: 168 LEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            ++     C+  PCRN  +C     G T   P
Sbjct: 391 SKID---YCILDPCRNGATCISSLSGFTCQCP 419



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/56 (37%), Positives = 31/56 (55%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   +TG  C++D  + C S  C HG  C++   G Y+C CP G+ G  CE+ +
Sbjct: 567 CICAPGFTGEECDIDINE-CDSNPCHHGGSCLDQPNG-YNCHCPHGWVGANCEIHL 620



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGYHGTYCE 167
           Y C C A  +G NC++ A DPCAS  C HG  +         Y C C  GY G  CE
Sbjct: 78  YSCTCPAGISGANCQLVA-DPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
 Frame = +3

Query: 48  VDAGDPCASAACRHGARCVE-----------DGRGDYSCDCPPGYHGTYCELEVSLDPLC 194
           + A  PCA+  CR+G  C              G   YSC CP G  G  C+L    DP C
Sbjct: 42  LSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVA--DP-C 98

Query: 195 VAGPCRNNGSCS 230
            + PC ++G+CS
Sbjct: 99  ASNPC-HHGNCS 109



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNG---GRCVDAVNNYTCDCTATGYTGARCE 415
           CTCP G +G NC+   D C+ +  C +G        + + Y C C   GY G  CE
Sbjct: 80  CTCPAGISGANCQLVADPCA-SNPCHHGNCSSSSSSSSDGYLCICN-EGYEGPNCE 133



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +3

Query: 81  CRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C    +C  +     +SC C   Y GT+CE     D  C   PC+NN SC
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYD-ACQRKPCQNNASC 364


>Z12172-1|CAA78163.1|  383|Homo sapiens putative homeotic protein
           protein.
          Length = 383

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 243



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV      Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDGGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250

Query: 183 DP 188
            P
Sbjct: 251 SP 252



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C     D C  S  C HG  C E G+    C C  G+ G  C+ +V   
Sbjct: 43  CRCHVGWQGPLC-----DQCVTSPGCLHGL-CGEPGQ----CICTDGWDGELCDRDVRA- 91

Query: 186 PLCVAGPCRNNGSCSVPPGG 245
             C + PC NNG+C    GG
Sbjct: 92  --CSSAPCANNGTCVSLDGG 109


>U77914-1|AAC50909.1|  263|Homo sapiens soluble protein Jagged
           protein.
          Length = 263

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 33/89 (37%), Positives = 43/89 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  C  + ++CS    C N G CVD  N Y C+C A G+ G  C  N+NEC+
Sbjct: 26  CVCKEGWEGPICAQNTNDCS-PHPCYNSGTCVDGDNWYRCEC-APGFAGPDCRININECQ 83

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGS 523
                 G   C D   G+ C C P   G+
Sbjct: 84  SSPCAFG-ATCVDEINGYRCVCPPGHSGA 111



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +C ++  + C S+ C  GA CV++  G Y C CPPG+ G  C+ EVS 
Sbjct: 62  YRCECAPGFAGPDCRININE-CQSSPCAFGATCVDEING-YRCVCPPGHSGAKCQ-EVSG 118

Query: 183 DPLCVAGPCRNNGS 224
            P    G    +G+
Sbjct: 119 RPCITMGSVIPDGA 132



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 21/53 (39%), Positives = 33/53 (62%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C PG+ G +C  +++EC  ++ C  G  CVD +N Y C C   G++GA+C+
Sbjct: 64  CECAPGFAGPDCRININECQ-SSPCAFGATCVDEINGYRCVC-PPGHSGAKCQ 114



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/75 (29%), Positives = 34/75 (45%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C  +  D C+   C +   CV DG   Y C+C PG+ G  C + ++ 
Sbjct: 24  FTCVCKEGWEGPICAQNTND-CSPHPCYNSGTCV-DGDNWYRCECAPGFAGPDCRININ- 80

Query: 183 DPLCVAGPCRNNGSC 227
              C + PC    +C
Sbjct: 81  --ECQSSPCAFGATC 93



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 22/64 (34%), Positives = 27/64 (42%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           C NGG CV    ++TC C   G+ G  C  N N+C         G C D    + C C P
Sbjct: 11  CHNGGTCVVNGESFTCVC-KEGWEGPICAQNTNDC-SPHPCYNSGTCVDGDNWYRCECAP 68

Query: 509 ATPG 520
              G
Sbjct: 69  GFAG 72


>U15981-1|AAA75365.1|  310|Homo sapiens dlk protein.
          Length = 310

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV      Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDGGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVD---AVNNYTCDCTATGYTGARCETNV 424
           C+C PGY+G++C+     C    + C +GG CVD     ++ +C C   G++G  CE   
Sbjct: 113 CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPP-GFSGNFCEIVA 171

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           N C  +      GVC D  G F C C
Sbjct: 172 NSCTPNPCE-NDGVCTDIGGDFRCRC 196



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/86 (31%), Positives = 35/86 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVC 496
            V  C       G      T G  +C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQGQAIC 233



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C    GG + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDGGLYECSCAPGYSG 121



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C     D C  S  C HG  C E G+    C C  G+ G  C+ +V   
Sbjct: 43  CRCQPGWQGPLC-----DQCVTSPGCLHGL-CGEPGQ----CICTDGWDGELCDRDVRA- 91

Query: 186 PLCVAGPCRNNGSCSVPPGG 245
             C + PC NNG+C    GG
Sbjct: 92  --CSSAPCANNGTCVSLDGG 109



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 12/43 (27%), Positives = 21/43 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSC 131
           + C C A +    C     + CAS+ C++G  C++  +G   C
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQGQAIC 233


>U15979-1|AAA75364.1|  382|Homo sapiens dlk protein.
          Length = 382

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 243



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV      Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDGGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C    GG + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDGGLYECSCAPGYSG 121



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250

Query: 183 DP 188
            P
Sbjct: 251 SP 252



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCA-SAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C     D C  S  C HG  C E G+    C C  G+ G  C+ +V   
Sbjct: 43  CRCQPGWQGPLC-----DQCVTSPGCLHGL-CGEPGQ----CICTDGWDGELCDRDVRA- 91

Query: 186 PLCVAGPCRNNGSCSVPPGG 245
             C + PC NNG+C    GG
Sbjct: 92  --CSSAPCANNGTCVSLDGG 109



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>DQ309460-1|ABC26875.1|  231|Homo sapiens delta-like 1 protein.
          Length = 231

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 24  YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 82

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 83  VAN---SCTPNPCENDGVCT-DIGGD 104



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 63  RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 120

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 121 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 156



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC-SGAAACLNGGRCVD---AVNNYTCDCTATGYTGARCETNV 424
           C+C PGY+G++C+     C    + C +GG CVD     ++ +C C   G++G  CE   
Sbjct: 26  CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLC-PPGFSGNFCEIVA 84

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           N C  +      GVC D  G F C C
Sbjct: 85  NSCTPNPCE-NDGVCTDIGGDFRCRC 109



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 69  CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 123

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 124 NCASSPCQNGGTC 136



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCV--AGPCRNNGSC 227
           C+SA C +   CV    G Y C C PGY G  C+ +   D  CV    PC++ G+C
Sbjct: 5   CSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---DGPCVINGSPCQHGGTC 57



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 5/80 (6%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNECEEDRALCGH-GVCY 472
           DV  CS +A C N G CV   +  Y C C A GY+G  C+     C  + + C H G C 
Sbjct: 1   DVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPCVINGSPCQHGGTCV 58

Query: 473 DTYG---GFVCACQPATPGS 523
           D  G      C C P   G+
Sbjct: 59  DDEGRASHASCLCPPGFSGN 78



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 105 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 163

Query: 183 DP 188
            P
Sbjct: 164 SP 165


>DQ138965-1|AAZ66768.1|  203|Homo sapiens truncated brevideltinin
           protein.
          Length = 203

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVD---AVNNYTCDCTATGYTGARCETNV 424
           C+C PGY+G++C+     C    + C +GG CVD     ++ +C C   G++G  CE   
Sbjct: 113 CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPP-GFSGNFCEIVA 171

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           N C  +      GVC D  G F C C   +  S
Sbjct: 172 NSCTPNPCE-NDGVCTDIGGDFRCRCSSRSTAS 203



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 18/50 (36%), Positives = 26/50 (52%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C++
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCSS 198



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>DQ126100-1|AAZ38943.1|  212|Homo sapiens brevideltin protein.
          Length = 212

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVD---AVNNYTCDCTATGYTGARCETNV 424
           C+C PGY+G++C+     C    + C +GG CVD     ++ +C C   G++G  CE   
Sbjct: 113 CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPP-GFSGNFCEIVA 171

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           N C  +      GVC D  G F C C
Sbjct: 172 NSCTPNPCE-NDGVCTDIGGDFRCRC 196



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 21/60 (35%), Positives = 29/60 (48%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C +
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSS 207



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 18/52 (34%), Positives = 25/52 (48%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTC 205



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>DQ017081-1|AAY40461.1|  315|Homo sapiens secredeltin protein.
          Length = 315

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVD---AVNNYTCDCTATGYTGARCETNV 424
           C+C PGY+G++C+     C    + C +GG CVD     ++ +C C   G++G  CE   
Sbjct: 113 CSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPP-GFSGNFCEIVA 171

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           N C  +      GVC D  G F C C
Sbjct: 172 NSCTPNPCE-NDGVCTDIGGDFRCRC 196



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 23/66 (34%), Positives = 31/66 (46%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECE 436
            V + E
Sbjct: 208 PVQQPE 213



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 19/56 (33%), Positives = 26/56 (46%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPV 209



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>BC014015-1|AAH14015.1|  383|Homo sapiens delta-like 1 homolog
           (Drosophila) protein.
          Length = 383

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 243



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250

Query: 183 DP 188
            P
Sbjct: 251 SP 252



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>BC013197-1|AAH13197.1|  383|Homo sapiens delta-like 1 homolog
           (Drosophila) protein.
          Length = 383

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 243



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250

Query: 183 DP 188
            P
Sbjct: 251 SP 252



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>BC007741-1|AAH07741.1|  383|Homo sapiens delta-like 1 homolog
           (Drosophila) protein.
          Length = 383

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCA--SAACRHGARCVED-GRGDY-SCDCPPGYHGTYCEL 170
           YEC C   Y+G +C+   G PC    + C+HG  CV+D GR  + SC CPPG+ G +CE+
Sbjct: 111 YECSCAPGYSGKDCQKKDG-PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169

Query: 171 EVSLDPLCVAGPCRNNGSCSVPPGGD 248
             +    C   PC N+G C+   GGD
Sbjct: 170 VAN---SCTPNPCENDGVCT-DIGGD 191



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 30/96 (31%), Positives = 39/96 (40%)
 Frame = +2

Query: 239 RRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET 418
           R  H  C CPPG++G  CE   + C+    C N G C D   ++ C C A G+    C  
Sbjct: 150 RASHASCLCPPGFSGNFCEIVANSCT-PNPCENDGVCTDIGGDFRCRCPA-GFIDKTCSR 207

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGST 526
            V  C       G      T   + C C+P   G T
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLT 243



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNN-YTCDCTATGYTGARCETNVNEC 433
           C C  G+ G  C+ DV  CS +A C N G CV   +  Y C C A GY+G  C+     C
Sbjct: 74  CICTDGWDGELCDRDVRACS-SAPCANNGTCVSLDDGLYECSC-APGYSGKDCQKKDGPC 131

Query: 434 EEDRALCGH-GVCYDTYG---GFVCACQPATPGS 523
             + + C H G C D  G      C C P   G+
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGN 165



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           +C CT  + G  C+ D    C+SA C +   CV    G Y C C PGY G  C+ +   D
Sbjct: 73  QCICTDGWDGELCDRDVR-ACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKK---D 128

Query: 186 PLCV--AGPCRNNGSC 227
             CV    PC++ G+C
Sbjct: 129 GPCVINGSPCQHGGTC 144



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 25/73 (34%), Positives = 36/73 (49%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   ++GN CE+ A   C    C +   C + G GD+ C CP G+    C   V+   
Sbjct: 156 CLCPPGFSGNFCEIVANS-CTPNPCENDGVCTDIG-GDFRCRCPAGFIDKTCSRPVT--- 210

Query: 189 LCVAGPCRNNGSC 227
            C + PC+N G+C
Sbjct: 211 NCASSPCQNGGTC 223



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 30/62 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C A +    C     + CAS+ C++G  C++  +  Y C C P + G  C  + +L
Sbjct: 192 FRCRCPAGFIDKTCSRPVTN-CASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRAL 250

Query: 183 DP 188
            P
Sbjct: 251 SP 252



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C C PG+ G  C    D+C  +  CL+ G C +      C CT  G+ G  C+ +V  C
Sbjct: 42  VCRCQPGWQGPLC----DQCVTSPGCLH-GLCGEPGQ---CICT-DGWDGELCDRDVRAC 92

Query: 434 EEDRALCGHGVCYDTYGG-FVCACQPATPG 520
                   +G C     G + C+C P   G
Sbjct: 93  -SSAPCANNGTCVSLDDGLYECSCAPGYSG 121



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 16/43 (37%), Positives = 20/43 (46%)
 Frame = +3

Query: 120 DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGD 248
           D  C C PG+ G  C+  V+  P C+ G C   G C    G D
Sbjct: 40  DNVCRCQPGWQGPLCDQCVT-SPGCLHGLCGEPGQCICTDGWD 81


>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
           factor-beta binding protein 4L protein.
          Length = 1624

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/87 (40%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LC CP GY     G +C+ DVDEC+ +      G C +   ++ C C A G+ G+ CE +
Sbjct: 653 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPA-GFRGSACEED 710

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           V+EC ++   CG G C +T G F CAC
Sbjct: 711 VDECAQEPPPCGPGRCDNTAGSFHCAC 737



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVN 427
           C CP G+ G  CE DVDEC+        GRC +   ++ C C A   +   GA C+ +V+
Sbjct: 696 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 754

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
           EC      C +G C +T G F C C     P +  + C  V
Sbjct: 755 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDV 795



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
 Frame = +2

Query: 263  CPPGY-TGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE----TNV 424
            CP G+   R   TDVDECS GA  C   G C +   ++ C C A GY           +V
Sbjct: 821  CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC-APGYRAPSGRPGPCADV 879

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            NEC E      HG C +T G F C C P   PG     C
Sbjct: 880  NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 918



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C+C PGY   +GR     DV+EC     C   G C++   ++ C C A GY     GA C
Sbjct: 860  CSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC-APGYRPGPRGASC 918

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
              +V+EC E+  LC  G+C +T G F C C P
Sbjct: 919  -LDVDECSEED-LCQSGICTNTDGSFECICPP 948



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
           C C PG+    R  E  DVDEC       + GRC +   ++ C C A GY     GA C+
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA-GYQAAPHGASCQ 670

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +V+EC +   LCG G C +  G F C C     GS
Sbjct: 671 -DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 705



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257  CT--CPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---- 409
            CT  C PGY    G  C+ DVDEC   + C     C +   ++ C C   GY GAR    
Sbjct: 1031 CTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ-GYEGARDGRH 1088

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP 517
            C  +VNECE  + +CG  +C +  G F+C C P +P
Sbjct: 1089 C-VDVNECETLQGVCGAALCENVEGSFLCVC-PNSP 1122



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRA---L 451
            E + +EC     C NG RCV     +TC C   GY    T   C  ++NEC+E  A   L
Sbjct: 1531 ELEAEECGILDGCTNG-RCVRVPEGFTCRCF-DGYRLDMTRMAC-VDINECDEAEAASPL 1587

Query: 452  CGHGVCYDTYGGFVCACQP 508
            C +  C +T G F C C+P
Sbjct: 1588 CVNARCLNTDGSFRCICRP 1606



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCE 415
           C C  G+     G  C  DVDEC         GRC ++  ++ C C      G   A C 
Sbjct: 570 CACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC- 627

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +V+EC      C  G C +T G F+C C
Sbjct: 628 LDVDECHRVPPPCDLGRCENTPGSFLCVC 656



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGR---NCETDVDECS--GAAACLNGGRCVDAVNNYTCDC 382
            ++ + +P     +  C PGY       C+ DVDEC   G   C    RC +   +Y C  
Sbjct: 976  QRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTP 1033

Query: 383  TAT-GYT---GARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
                GY    G  C+ +V+EC  +R+ CG H VC +  G F C C     G+
Sbjct: 1034 ACDPGYQPTPGGGCQ-DVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1083



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCET 418
            C C  GY   T R    D DEC+       GGRCV+ V +Y C C        +  RC +
Sbjct: 1279 CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1338

Query: 419  NVNECEEDRALCGHGVCYDTYGG-FVCACQPATPGSTATGC 538
            N ++  +D      GVC+   G   VC+       +T T C
Sbjct: 1339 NESQSLDDNL----GVCWQEVGADLVCSHPRLDRQATYTEC 1375



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
 Frame = +2

Query: 341 GRCVDAVNNYTCDCTATGYT----GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           GRC+   + YTC C + G+     G RC  +V+EC      C  G C ++ G F C C P
Sbjct: 559 GRCISRPSGYTCACDS-GFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGP 616

Query: 509 A-TPGSTATGC 538
               G  A  C
Sbjct: 617 GFRAGPRAAEC 627



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCEL 170
           + C C A + G+ CE D  D CA      G    ++  G + C CP G+     G  C+ 
Sbjct: 694 FRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 752

Query: 171 E---VSLDPLCVAGPCRN-NGS--CSVPPG 242
                   P C  G C N  GS  C  P G
Sbjct: 753 VDECARSPPPCTYGRCENTEGSFQCVCPMG 782



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGR-----GDYSCDCPPGY----H 152
            + C C   Y   +       PCA    C  G  C   G      G ++C C PGY     
Sbjct: 858  FRCSCAPGYRAPS---GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 914

Query: 153  GTYC--ELEVSLDPLCVAGPCRN-NGS--CSVPPG 242
            G  C    E S + LC +G C N +GS  C  PPG
Sbjct: 915  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 949



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
 Frame = +3

Query: 9   CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C A Y     G +C+ D  D C  +    G    ++  G + C CP G+ G+ CE +V
Sbjct: 654 CVCPAGYQAAPHGASCQ-DV-DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 711

Query: 177 ----SLDPLCVAGPCRNN-GS--CSVPPG 242
                  P C  G C N  GS  C+ P G
Sbjct: 712 DECAQEPPPCGPGRCDNTAGSFHCACPAG 740



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
 Frame = +2

Query: 263 CPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           CP G+   N  CE DVDEC+    C + G C +    YTC C
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQH-GECANTRGGYTCVC 383



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDP 188
           C   +   N   +  D CA+   C+HG  C    RG Y+C CP G+         +S   
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHG-ECANT-RGGYTCVCPDGFLLDSSRSSCISQHV 401

Query: 189 LCVA-GPC---RNNGSCSVP 236
           +  A GPC     +G CS+P
Sbjct: 402 ISEAKGPCFRVLRDGGCSLP 421



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +2

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CE +V+EC      C HG C +T GG+ C C
Sbjct: 355 CE-DVDECATG-GRCQHGECANTRGGYTCVC 383



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
 Frame = +3

Query: 96  RCVEDGRGDYSCDCPPGY----HGTYCE--LEVSLDP-LCVAGPCRN-NGS--CSVPPG 242
           RC E+  G + C CP GY    HG  C+   E +  P LC  G C+N  GS  C  P G
Sbjct: 644 RC-ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAG 701



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           C +G  CV+  R    C CPP + G +C+L  S
Sbjct: 157 CHNGGVCVKPDR----CLCPPDFAGKFCQLHSS 185



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
 Frame = +3

Query: 3   YECHCTA--RYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH----GT 158
           + C C A  R  G        D CA +   C +G RC E+  G + C CP G+     G+
Sbjct: 733 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RC-ENTEGSFQCVCPMGFQPNAAGS 790

Query: 159 YCE 167
            CE
Sbjct: 791 ECE 793


>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
           factor-beta binding protein 4S protein.
          Length = 1557

 Score = 74.5 bits (175), Expect = 3e-13
 Identities = 35/87 (40%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LC CP GY     G +C+ DVDEC+ +      G C +   ++ C C A G+ G+ CE +
Sbjct: 586 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPA-GFRGSACEED 643

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           V+EC ++   CG G C +T G F CAC
Sbjct: 644 VDECAQEPPPCGPGRCDNTAGSFHCAC 670



 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVN 427
           C CP G+ G  CE DVDEC+        GRC +   ++ C C A   +   GA C+ +V+
Sbjct: 629 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 687

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
           EC      C +G C +T G F C C     P +  + C  V
Sbjct: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNAAGSECEDV 728



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
 Frame = +2

Query: 263  CPPGY-TGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE----TNV 424
            CP G+   R   TDVDECS GA  C   G C +   ++ C C A GY           +V
Sbjct: 754  CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC-APGYRAPSGRPGPCADV 812

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            NEC E      HG C +T G F C C P   PG     C
Sbjct: 813  NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 851



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C+C PGY   +GR     DV+EC     C   G C++   ++ C C A GY     GA C
Sbjct: 793  CSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC-APGYRPGPRGASC 851

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
              +V+EC E+  LC  G+C +T G F C C P
Sbjct: 852  -LDVDECSEED-LCQSGICTNTDGSFECICPP 881



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
           C C PG+    R  E  DVDEC       + GRC +   ++ C C A GY     GA C+
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA-GYQAAPHGASCQ 603

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +V+EC +   LCG G C +  G F C C     GS
Sbjct: 604 -DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 638



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257  CT--CPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---- 409
            CT  C PGY    G  C+ DVDEC   + C     C +   ++ C C   GY GAR    
Sbjct: 964  CTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ-GYEGARDGRH 1021

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP 517
            C  +VNECE  + +CG  +C +  G F+C C P +P
Sbjct: 1022 C-VDVNECETLQGVCGAALCENVEGSFLCVC-PNSP 1055



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRA---L 451
            E + +EC     C NG RCV     +TC C   GY    T   C  ++NEC+E  A   L
Sbjct: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCF-DGYRLDMTRMAC-VDINECDEAEAASPL 1520

Query: 452  CGHGVCYDTYGGFVCACQP 508
            C +  C +T G F C C+P
Sbjct: 1521 CVNARCLNTDGSFRCICRP 1539



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCE 415
           C C  G+     G  C  DVDEC         GRC ++  ++ C C      G   A C 
Sbjct: 503 CACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC- 560

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +V+EC      C  G C +T G F+C C
Sbjct: 561 LDVDECHRVPPPCDLGRCENTPGSFLCVC 589



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGR---NCETDVDECS--GAAACLNGGRCVDAVNNYTCDC 382
            ++ + +P     +  C PGY       C+ DVDEC   G   C    RC +   +Y C  
Sbjct: 909  QRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTP 966

Query: 383  TAT-GYT---GARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
                GY    G  C+ +V+EC  +R+ CG H VC +  G F C C     G+
Sbjct: 967  ACDPGYQPTPGGGCQ-DVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1016



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCET 418
            C C  GY   T R    D DEC+       GGRCV+ V +Y C C        +  RC +
Sbjct: 1212 CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1271

Query: 419  NVNECEEDRALCGHGVCYDTYGG-FVCACQPATPGSTATGC 538
            N ++  +D      GVC+   G   VC+       +T T C
Sbjct: 1272 NESQSLDDNL----GVCWQEVGADLVCSHPRLDRQATYTEC 1308



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
 Frame = +2

Query: 341 GRCVDAVNNYTCDCTATGYT----GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           GRC+   + YTC C + G+     G RC  +V+EC      C  G C ++ G F C C P
Sbjct: 492 GRCISRPSGYTCACDS-GFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGP 549

Query: 509 A-TPGSTATGC 538
               G  A  C
Sbjct: 550 GFRAGPRAAEC 560



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCEL 170
           + C C A + G+ CE D  D CA      G    ++  G + C CP G+     G  C+ 
Sbjct: 627 FRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 685

Query: 171 E---VSLDPLCVAGPCRN-NGS--CSVPPG 242
                   P C  G C N  GS  C  P G
Sbjct: 686 VDECARSPPPCTYGRCENTEGSFQCVCPMG 715



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGR-----GDYSCDCPPGY----H 152
            + C C   Y   +       PCA    C  G  C   G      G ++C C PGY     
Sbjct: 791  FRCSCAPGYRAPS---GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 847

Query: 153  GTYC--ELEVSLDPLCVAGPCRN-NGS--CSVPPG 242
            G  C    E S + LC +G C N +GS  C  PPG
Sbjct: 848  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 882



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
 Frame = +3

Query: 9   CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C A Y     G +C+ D  D C  +    G    ++  G + C CP G+ G+ CE +V
Sbjct: 587 CVCPAGYQAAPHGASCQ-DV-DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 644

Query: 177 ----SLDPLCVAGPCRNN-GS--CSVPPG 242
                  P C  G C N  GS  C+ P G
Sbjct: 645 DECAQEPPPCGPGRCDNTAGSFHCACPAG 673



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
 Frame = +2

Query: 263 CPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           CP G+   N  CE DVDEC+    C + G C +    YTC C
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQH-GECANTRGGYTCVC 316



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDP 188
           C   +   N   +  D CA+   C+HG  C    RG Y+C CP G+         +S   
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHG-ECANT-RGGYTCVCPDGFLLDSSRSSCISQHV 334

Query: 189 LCVA-GPC---RNNGSCSVP 236
           +  A GPC     +G CS+P
Sbjct: 335 ISEAKGPCFRVLRDGGCSLP 354



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +2

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CE +V+EC      C HG C +T GG+ C C
Sbjct: 288 CE-DVDECATG-GRCQHGECANTRGGYTCVC 316



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
 Frame = +3

Query: 96  RCVEDGRGDYSCDCPPGY----HGTYCE--LEVSLDP-LCVAGPCRN-NGS--CSVPPG 242
           RC E+  G + C CP GY    HG  C+   E +  P LC  G C+N  GS  C  P G
Sbjct: 577 RC-ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAG 634



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           C +G  CV+  R    C CPP + G +C+L  S
Sbjct: 90  CHNGGVCVKPDR----CLCPPDFAGKFCQLHSS 118



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
 Frame = +3

Query: 3   YECHCTA--RYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH----GT 158
           + C C A  R  G        D CA +   C +G RC E+  G + C CP G+     G+
Sbjct: 666 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RC-ENTEGSFQCVCPMGFQPNAAGS 723

Query: 159 YCE 167
            CE
Sbjct: 724 ECE 726


>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
           protein-4 protein.
          Length = 1587

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 35/87 (40%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LC CP GY     G +C+ DVDEC+ +      G C +   ++ C C A G+ G+ CE +
Sbjct: 616 LCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGGCKNLPGSFRCVCPA-GFRGSACEED 673

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           V+EC ++   CG G C +T G F CAC
Sbjct: 674 VDECAQEPPPCGPGRCDNTAGSFHCAC 700



 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 38/97 (39%), Positives = 49/97 (50%), Gaps = 8/97 (8%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCETNV 424
           C CP G+ G  CE DVDEC+        GRC +   ++ C C A G+     GA C+ +V
Sbjct: 659 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA-GFRSRGPGAPCQ-DV 716

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC----QPATPGS 523
           +EC      C +G C +T G F C C    QP T GS
Sbjct: 717 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGS 753



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 39/100 (39%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
 Frame = +2

Query: 260  TCPPGY-TGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE----TN 421
            TCP G+   R   TDVDECS GA  C   G C +   ++ C C A GY           +
Sbjct: 783  TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC-APGYRAPSGRPGPCAD 841

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            VNEC E      HG C +T G F C C P   PG     C
Sbjct: 842  VNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 881



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C+C PGY   +GR     DV+EC     C   G C++   ++ C C A GY     GA C
Sbjct: 823  CSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC-APGYRPGPRGASC 881

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
              +V+EC E+  LC  G+C +T G F C C P
Sbjct: 882  -LDVDECSEED-LCQSGICTNTDGSFECICPP 911



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
           C C PG+    R  E  DVDEC       + GRC +   ++ C C A GY     GA C+
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA-GYQAAPHGASCQ 633

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
            +V+EC +   LCG G C +  G F C C     GS
Sbjct: 634 -DVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGS 668



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257  CT--CPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---- 409
            CT  C PGY    G  C+ DVDEC   + C     C +   ++ C C   GY GAR    
Sbjct: 994  CTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ-GYEGARDGRH 1051

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP 517
            C  +VNECE  + +CG  +C +  G F+C C P +P
Sbjct: 1052 C-VDVNECETLQGVCGAALCENVEGSFLCVC-PNSP 1085



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCE 415
           C C  G+     G  C  DVDEC         GRC ++  ++ C C      G   A C 
Sbjct: 533 CACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAEC- 590

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +V+EC      C  G C +T G F+C C
Sbjct: 591 LDVDECHRVPPPCDLGRCENTPGSFLCVC 619



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRA---L 451
            E + +EC     C N  RCV     +TC C   GY    T   C  ++NEC+E  A   L
Sbjct: 1494 ELEAEECGILDGCTND-RCVRVPEGFTCRCF-DGYRLDMTRMAC-VDINECDEAEAASPL 1550

Query: 452  CGHGVCYDTYGGFVCACQP 508
            C +  C +T G F C C+P
Sbjct: 1551 CVNARCLNTDGSFRCICRP 1569



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 10/112 (8%)
 Frame = +2

Query: 218  RQLQRAPRRRHLLCTCPPGYTGR---NCETDVDECS--GAAACLNGGRCVDAVNNYTCDC 382
            ++ + +P     +  C PGY       C+ DVDEC   G   C    RC +   +Y C  
Sbjct: 939  QRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTP 996

Query: 383  TAT-GYT---GARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
                GY    G  C+ +V+EC  +R+ CG H VC +  G F C C     G+
Sbjct: 997  ACDPGYQPTPGGGCQ-DVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1046



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCET 418
            C C  GY   T R    D DEC+       GGRCV+ V +Y C C        +  RC +
Sbjct: 1242 CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1301

Query: 419  NVNECEEDRALCGHGVCYDTYGG-FVCACQPATPGSTATGC 538
            N ++  +D      GVC+   G   VC+       +T T C
Sbjct: 1302 NESQSLDDNL----GVCWQEVGADLVCSHPRLDRQATYTEC 1338



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
 Frame = +2

Query: 341 GRCVDAVNNYTCDCTATGYT----GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           GRC+   + YTC C + G+     G RC  +V+EC      C  G C ++ G F C C P
Sbjct: 522 GRCISRPSGYTCACDS-GFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGP 579

Query: 509 A-TPGSTATGC 538
               G  A  C
Sbjct: 580 GFRAGPRAAEC 590



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCEL 170
           + C C A + G+ CE D  D CA      G    ++  G + C CP G+     G  C+ 
Sbjct: 657 FRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 715

Query: 171 E---VSLDPLCVAGPCRN-NGS--CSVPPG 242
                   P C  G C N  GS  C  P G
Sbjct: 716 VDECARSPPPCTYGRCENTEGSFQCVCPMG 745



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGR-----GDYSCDCPPGY----H 152
            + C C   Y   +       PCA    C  G  C   G      G ++C C PGY     
Sbjct: 821  FRCSCAPGYRAPS---GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877

Query: 153  GTYC--ELEVSLDPLCVAGPCRN-NGS--CSVPPG 242
            G  C    E S + LC +G C N +GS  C  PPG
Sbjct: 878  GASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 912



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
 Frame = +2

Query: 263 CPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           CP G+   N  CE DVDEC+    C + G C +    YTC C
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQH-GECANTRGGYTCVC 346



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
 Frame = +3

Query: 9   CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C A Y     G +C+ D  D C  +    G    ++  G + C CP G+ G+ CE +V
Sbjct: 617 CVCPAGYQAAPHGASCQ-DV-DECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDV 674

Query: 177 ----SLDPLCVAGPCRNN-GS--CSVPPG 242
                  P C  G C N  GS  C+ P G
Sbjct: 675 DECAQEPPPCGPGRCDNTAGSFHCACPAG 703



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDP 188
           C   +   N   +  D CA+   C+HG  C    RG Y+C CP G+         +S   
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHG-ECANT-RGGYTCVCPDGFLLDSSRSSCISQHV 364

Query: 189 LCVA-GPC---RNNGSCSVP 236
           +  A GPC     +G CS+P
Sbjct: 365 ISEAKGPCFRVLRDGGCSLP 384



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 14/31 (45%), Positives = 18/31 (58%)
 Frame = +2

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CE +V+EC      C HG C +T GG+ C C
Sbjct: 318 CE-DVDECATG-GRCQHGECANTRGGYTCVC 346



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
           C +G  CV+  R    C CPP + G +C+L  S
Sbjct: 120 CHNGGVCVKPDR----CFCPPDFAGKFCQLHSS 148



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
 Frame = +3

Query: 96  RCVEDGRGDYSCDCPPGY----HGTYCE--LEVSLDP-LCVAGPCRN-NGS--CSVPPG 242
           RC E+  G + C CP GY    HG  C+   E +  P LC  G C+N  GS  C  P G
Sbjct: 607 RC-ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAG 664



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
 Frame = +3

Query: 3   YECHCTA--RYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH----GT 158
           + C C A  R  G        D CA +   C +G RC E+  G + C CP G+     G+
Sbjct: 696 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RC-ENTEGSFQCVCPMGFQPNTAGS 753

Query: 159 YCE 167
            CE
Sbjct: 754 ECE 756


>BX537434-1|CAD97676.1|  236|Homo sapiens hypothetical protein
           protein.
          Length = 236

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 149 IP-GHCQHGGTCLNLPGSYQCQC 170



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPET 213



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 145 NECDIPGHCQHGGTCLNLPG 164



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>BC084572-1|AAH84572.1|  343|Homo sapiens NOTCH2NL protein protein.
          Length = 343

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 199 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 255

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 256 IP-GHCQHGGTCLNLPGSYQCQC 277



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 236 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 294

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 295 PSPCVNG-GTCRQTGDFTFECNCLPET 320



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 234 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 289

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 290 YVPCAPSPCVNGGTC 304



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 197 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 251

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 252 NECDIPGHCQHGGTCLNLPG 271



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 158 CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 213

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 214 DACLSHPCANGSTCT 228



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 119 CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 175

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 176 PCFVSRPCLNGGTCHM-LSRDTY 197



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 119 CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 175

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 176 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 207



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 158 CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 215

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 216 CLSHP--CANGSTCTTVANQFSCKC 238



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 273 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 318



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 103 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 147


>BC010154-1|AAH10154.3|  236|Homo sapiens Notch homolog 2
           (Drosophila) N-terminal like protein.
          Length = 236

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 149 IP-GHCQHGGTCLNLPGSYQCQC 170



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPET 213



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 145 NECDIPGHCQHGGTCLNLPG 164



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>AL592307-2|CAH73994.1|  230|Homo sapiens Notch homolog 2
           (Drosophila) N-terminal like protein.
          Length = 230

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 149 IP-GHCQHGGTCLNLPGSYQCQC 170



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C PAT
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPAT 213



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 145 NECDIPGHCQHGGTCLNLPG 164



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>AL592307-1|CAH73993.1|  236|Homo sapiens Notch homolog 2
           (Drosophila) N-terminal like protein.
          Length = 236

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 92  CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 148

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 149 IP-GHCQHGGTCLNLPGSYQCQC 170



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 33/87 (37%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 129 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 187

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C P T
Sbjct: 188 PSPCVNG-GTCRQTGDFTFECNCLPET 213



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 127 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 182

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 183 YVPCAPSPCVNGGTC 197



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 90  YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 144

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 145 NECDIPGHCQHGGTCLNLPG 164



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 106

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 107 DACLSHPCANGSTCT 121



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   + G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 12  CKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 68

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 69  PCFVSRPCLNGGTCHM-LSRDTY 90



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 33/95 (34%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G+ G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 12  CKCPEGFLGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 68

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 69  PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 100



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDE-CSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG +C+      C  +  CLNGG C + + + Y C C   G+TG  C+   + 
Sbjct: 51  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC-QVGFTGKECQW-TDA 108

Query: 431 CEEDRALCGHG-VCYDTYGGFVCAC 502
           C      C +G  C      F C C
Sbjct: 109 CLSHP--CANGSTCTTVANQFSCKC 131



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 166 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 211



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 17/43 (39%), Positives = 21/43 (48%)
 Frame = +3

Query: 99  CVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 2   CVTYHNGTGYCKCPEGFLGEYCQ---HRDP-CEKNRCQNGGTC 40


>AK075065-1|BAC11381.1|  269|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90584 fis, clone PLACE1000740, highly similar to
           Neurogenic locus notch homolog protein 2 precursor. ).
          Length = 269

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 34/83 (40%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           CTC  G+TG+ C+   D C  +  C NG  C    N ++C C  TG+TG +CET+VNEC+
Sbjct: 131 CTCQVGFTGKECQW-TDACL-SHPCANGSTCTTVANQFSCKC-LTGFTGQKCETDVNECD 187

Query: 437 EDRALCGH-GVCYDTYGGFVCAC 502
                C H G C +  G + C C
Sbjct: 188 IP-GHCQHGGTCLNLPGSYQCQC 209



 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG+ CETDV+EC     C +GG C++   +Y C C   G+TG  C++    C 
Sbjct: 168 CKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC-LQGFTGQYCDSLYVPCA 226

Query: 437 EDRALCGHGVCYDTYG-GFVCACQPAT 514
               + G G C  T    F C C PAT
Sbjct: 227 PSPCVNG-GTCRQTGDFTFECNCLPAT 252



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 27/75 (36%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   +TG  CE D  +      C+HG  C+ +  G Y C C  G+ G YC+   SL
Sbjct: 166 FSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL-NLPGSYQCQCLQGFTGQYCD---SL 221

Query: 183 DPLCVAGPCRNNGSC 227
              C   PC N G+C
Sbjct: 222 YVPCAPSPCVNGGTC 236



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 27/80 (33%), Positives = 39/80 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           YEC C   +TG  C+    D C S  C +G+ C       +SC C  G+ G  CE +V  
Sbjct: 129 YECTCQVGFTGKECQWT--DACLSHPCANGSTCTTVA-NQFSCKCLTGFTGQKCETDV-- 183

Query: 183 DPLCVAGPCRNNGSCSVPPG 242
           +   + G C++ G+C   PG
Sbjct: 184 NECDIPGHCQHGGTCLNLPG 203



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPC-ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C C + +TG +C+     PC  S  C +G  C    R  Y C C  G+ G  C+      
Sbjct: 90  CRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----WT 145

Query: 186 PLCVAGPCRNNGSCS 230
             C++ PC N  +C+
Sbjct: 146 DACLSHPCANGSTCT 160



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGR-GDYSCDCPPGYHGTYCELEVSLD 185
           C C   ++G  C+    DPC    C++G  CV     G  +C C  G+ G  C+   S  
Sbjct: 51  CKCPEGFSGEYCQ--HRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTS-H 107

Query: 186 PLCVAGPCRNNGSCSVPPGGDTY 254
           P  V+ PC N G+C +    DTY
Sbjct: 108 PCFVSRPCLNGGTCHM-LSRDTY 129



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV--DAVNNYTCDCTATGYTGARCETNVNE 430
           C CP G++G  C+   D C     C NGG CV    +   TC C A+G+TG  C+ + + 
Sbjct: 51  CKCPEGFSGEYCQ-HRDPCE-KNRCQNGGTCVAQAMLGKATCRC-ASGFTGEDCQYSTSH 107

Query: 431 -CEEDRALCGHGVCY----DTYGGFVCACQPATPG 520
            C   R     G C+    DTY    C CQ    G
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTY---ECTCQVGFTG 139



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 16/47 (34%), Positives = 24/47 (51%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPP 143
           Y+C C   +TG  C+     PCA + C +G  C + G   + C+C P
Sbjct: 205 YQCQCLQGFTGQYCD-SLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C +   CV    G   C CP G+ G YC+     DP C    C+N G+C
Sbjct: 35  CVNEGMCVTYHNGTGYCKCPEGFSGEYCQ---HRDP-CEKNRCQNGGTC 79


>AC008273-1|AAF19247.2|  291|Homo sapiens unknown protein.
          Length = 291

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 33/90 (36%), Positives = 44/90 (48%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGYTG  C++ +D C     C NG  C+ +++ +TC C   GY G+ CE  V+ C 
Sbjct: 95  CVCLPGYTGELCQSKIDYCI-LDPCRNGATCISSLSGFTCQC-PEGYFGSACEEKVDPCA 152

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPGST 526
                  +G CY     F C C P   G T
Sbjct: 153 SSPCQ-NNGTCYVDGVHFTCNCSPGFTGPT 181



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/77 (42%), Positives = 44/77 (57%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTG  C+    D C    CR+GA C+    G ++C CP GY G+ CE +V  
Sbjct: 93  FTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKV-- 148

Query: 183 DPLCVAGPCRNNGSCSV 233
           DP C + PC+NNG+C V
Sbjct: 149 DP-CASSPCQNNGTCYV 164



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
           C CP GY G  CE  VD C+ ++ C N G C VD V ++TC+C + G+TG  C   ++ C
Sbjct: 133 CQCPEGYFGSACEEKVDPCA-SSPCQNNGTCYVDGV-HFTCNC-SPGFTGPTCAQLIDFC 189

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
               + C HG C      + C C P   G
Sbjct: 190 A--LSPCAHGTCRSVGTSYKCLCDPGYHG 216



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 34/84 (40%), Positives = 38/84 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PGY G  CE + +EC  +A CLN   C D VN Y C C A  Y G  CE   + C 
Sbjct: 208 CLCDPGYHGLYCEEEYNECL-SAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCA 265

Query: 437 EDRALCGHGVCYDTYGGFVCACQP 508
               L G     D   G  C C P
Sbjct: 266 NVSCLNGATCDSDGLNG-TCICAP 288



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 30/75 (40%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C+C+  +TG  C     D CA + C HG  C   G   Y C C PGYHG YCE E + 
Sbjct: 169 FTCNCSPGFTGPTC-AQLIDFCALSPCAHGT-CRSVGTS-YKCLCDPGYHGLYCEEEYN- 224

Query: 183 DPLCVAGPCRNNGSC 227
              C++ PC N  +C
Sbjct: 225 --ECLSAPCLNAATC 237



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y G+ CE +  DPCAS+ C++   C  DG   ++C+C PG+ G  C   +  
Sbjct: 131 FTCQCPEGYFGSACE-EKVDPCASSPCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDF 188

Query: 183 DPL--CVAGPCRNNGS---CSVPPG 242
             L  C  G CR+ G+   C   PG
Sbjct: 189 CALSPCAHGTCRSVGTSYKCLCDPG 213



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 30/85 (35%), Positives = 37/85 (43%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
           H  C C PG+TG  C   +D C+  + C + G C     +Y C C   GY G  CE   N
Sbjct: 168 HFTCNCSPGFTGPTCAQLIDFCA-LSPCAH-GTCRSVGTSYKCLCD-PGYHGLYCEEEYN 224

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC     L     C D   G+ C C
Sbjct: 225 ECLSAPCL-NAATCRDLVNGYECVC 248



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDA-----VNNYTCDCTATGYT 400
           P      CTC   Y G  CE + D C     C N   C+DA      +N+TC C   GYT
Sbjct: 46  PSEATFSCTCEEQYVGTFCE-EYDACQ-RKPCQNNASCIDANEKQDGSNFTCVC-LPGYT 102

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGS 523
           G  C++ ++ C  D    G   C  +  GF C C     GS
Sbjct: 103 GELCQSKIDYCILDPCRNG-ATCISSLSGFTCQCPEGYFGS 142



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVE-----DGRGDYSCDCPPGYHGTYCE 167
           + C C  +Y G  CE    D C    C++ A C++     DG  +++C C PGY G  C+
Sbjct: 51  FSCTCEEQYVGTFCE--EYDACQRKPCQNNASCIDANEKQDG-SNFTCVCLPGYTGELCQ 107

Query: 168 LEVSLDPLCVAGPCRNNGSCSVPPGGDTYSAP 263
            ++     C+  PCRN  +C     G T   P
Sbjct: 108 SKID---YCILDPCRNGATCISSLSGFTCQCP 136



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 23/49 (46%), Positives = 30/49 (61%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           YEC C A Y G +CE+   DPCA+ +C +GA C  DG    +C C PG+
Sbjct: 244 YECVCLAEYKGTHCELYK-DPCANVSCLNGATCDSDGLNG-TCICAPGF 290



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/75 (38%), Positives = 36/75 (48%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y+C C   Y G  CE +  + C SA C + A C +   G Y C C   Y GT+CEL    
Sbjct: 206 YKCLCDPGYHGLYCEEEYNE-CLSAPCLNAATCRDLVNG-YECVCLAEYKGTHCEL--YK 261

Query: 183 DPLCVAGPCRNNGSC 227
           DP C    C N  +C
Sbjct: 262 DP-CANVSCLNGATC 275



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +3

Query: 81  CRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           C    +C  +     +SC C   Y GT+CE     D  C   PC+NN SC
Sbjct: 36  CSGKGKCTTKPSEATFSCTCEEQYVGTFCE---EYD-ACQRKPCQNNASC 81


>AL359813-8|CAI23223.1|  377|Homo sapiens EGF-like-domain, multiple
           9 protein.
          Length = 377

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 37/96 (38%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAA-CLNGGRCVDAVN---NYTCDCTATGYTGARCETNV 424
           C C PG+ GR+CE     C  A + C NGG+C D      N+TC C   G+ GARCE NV
Sbjct: 111 CVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRC-LVGFVGARCEVNV 169

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
           ++C   R       C D    F C C     G   T
Sbjct: 170 DDCLM-RPCANGATCLDGINRFSCLCPEGFAGRFCT 204



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEV+  D C    C +GA C+ DG   +SC CP G+ G +C   ++L
Sbjct: 152 FTCRCLVGFVGARCEVNVDD-CLMRPCANGATCL-DGINRFSCLCPEGFAGRFC--TINL 207

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC+    C
Sbjct: 208 DD-CASRPCQRGARC 221



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 25/55 (45%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG-PCRNNGSCSVPPG 242
           C++G +C+ DG G+Y C C PG+HG  CE +    P   AG PCRN G C    G
Sbjct: 95  CQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG--PCEQAGSPCRNGGQCQDDQG 147



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C ++  D CAS  C+ GARC  D   D+ C CP GY G  CEL + +
Sbjct: 190 FSCLCPEGFAGRFCTINLDD-CASRPCQRGARC-RDRVHDFDCLCPSGYGGKTCELVLPV 247

Query: 183 --DPLCVAGPCRNNGSCSVPPGG 245
              P  V  P     +  VP  G
Sbjct: 248 PDPPTTVDTPLGPTSAVVVPATG 270



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 5/80 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRG---DYSCDCPPGYHGTYCE 167
           Y C C   + G +CE  AG PC  A + CR+G +C +D +G   +++C C  G+ G  CE
Sbjct: 109 YHCVCLPGFHGRDCERKAG-PCEQAGSPCRNGGQC-QDDQGFALNFTCRCLVGFVGARCE 166

Query: 168 LEVSLDPLCVAGPCRNNGSC 227
           + V  D  C+  PC N  +C
Sbjct: 167 VNVD-D--CLMRPCANGATC 183



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C CP G+ GR C  ++D+C+ +  C  G RC D V+++ C C  +GY G  CE
Sbjct: 192 CLCPEGFAGRFCTINLDDCA-SRPCQRGARCRDRVHDFDCLC-PSGYGGKTCE 242



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 30/112 (26%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDV-----------------------DE--CSGAAACLNGGRCV-DA 358
           C C PG+ G +CE  V                       DE  C+  + C NGG+C+ D 
Sbjct: 46  CRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWADEHICTTQSPCQNGGQCMYDG 105

Query: 359 VNNYTCDCTATGYTGARCETNVNECEEDRALCGH-GVCYDTYG---GFVCAC 502
              Y C C   G+ G  CE     CE+  + C + G C D  G    F C C
Sbjct: 106 GGEYHCVC-LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRC 156



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C+S     HG  C  DG    SC C PG+ G +CE  V + P C  G C     C
Sbjct: 27  DDCSSHCDLAHGC-CAPDG----SCRCDPGWEGLHCERCVRM-PGCQHGTCHQPWQC 77


>BC027939-1|AAH27939.1|  600|Homo sapiens SNED1 protein protein.
          Length = 600

 Score = 70.9 bits (166), Expect = 3e-12
 Identities = 36/88 (40%), Positives = 46/88 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C A + G +CE +  D C S+ C+HG RC E G G Y C CP  + G +CE  VS 
Sbjct: 48  YVCRCPAGFVGVHCETEV-DACDSSPCQHGGRC-ESGGGAYLCVCPESFFGYHCE-TVS- 103

Query: 183 DPLCVAGPCRNNGSCSVPPGGDTYSAPV 266
           DP C + PC   G C    G  + +  V
Sbjct: 104 DP-CFSSPCGGRGYCLASNGSHSCTCKV 130



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 31/89 (34%), Positives = 43/89 (48%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CP G+ G +CET+VD C  ++ C +GGRC      Y C C  + + G  CET  + C
Sbjct: 49  VCRCPAGFVGVHCETEVDACD-SSPCQHGGRCESGGGAYLCVCPES-FFGYHCETVSDPC 106

Query: 434 EEDRALCGHGVCYDTYGGFVCACQPATPG 520
                  G G C  + G   C C+    G
Sbjct: 107 FSS-PCGGRGYCLASNGSHSCTCKVGYTG 134



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 28/67 (41%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGH-GVCYDTY 481
           DEC  A  C NGG C +    Y C C A G+ G  CET V+ C  D + C H G C    
Sbjct: 28  DECR-AHPCRNGGSCRNLPGAYVCRCPA-GFVGVHCETEVDAC--DSSPCQHGGRCESGG 83

Query: 482 GGFVCAC 502
           G ++C C
Sbjct: 84  GAYLCVC 90



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 25/65 (38%), Positives = 33/65 (50%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C +  CR+G  C  +  G Y C CP G+ G +CE EV     C + PC++ G C    
Sbjct: 28  DECRAHPCRNGGSC-RNLPGAYVCRCPAGFVGVHCETEVD---ACDSSPCQHGGRCE--S 81

Query: 240 GGDTY 254
           GG  Y
Sbjct: 82  GGGAY 86



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 16/35 (45%), Positives = 21/35 (60%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           C+   C++G  CV  G   +SCDC PG+ G  CEL
Sbjct: 513 CSENPCQNGGTCVP-GADAHSCDCGPGFKGRRCEL 546



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C NGG CV   + ++CDC   G+ G RCE
Sbjct: 518 CQNGGTCVPGADAHSCDC-GPGFKGRRCE 545


>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
          Length = 3002

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-TDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
            C+C PG+ G   + TD+DECS G   C     C + + +Y C C   GYTG     T+++
Sbjct: 1479 CSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE-GYTGDGFTCTDLD 1537

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            EC E+  LCG+G C +  GG+ C C     P +    C  +
Sbjct: 1538 ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDI 1578



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCE 415
            C CP G+   +    CE D+DEC     C     C++   +Y CDC   GY   +  +C 
Sbjct: 1922 CECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKP-GYRFTSTGQCN 1979

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
               NEC+E   +C HG C DT G F C C
Sbjct: 1980 DR-NECQEIPNICSHGQCIDTVGSFYCLC 2007



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C+C PG+      R+C TD+DEC       +GG+C +    Y C C          +T  
Sbjct: 1352 CSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 1410

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA-TGCRRVRQ 553
            +VNEC+ +  +C  G C +T G F+C C     G    TGC  + +
Sbjct: 1411 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1456



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEEDRALCGHGVC 469
            D+DEC        GG+C++   ++ C C  TGY      R   +VNECE    +CG G C
Sbjct: 1737 DIDECQELPGLCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETP-GICGPGTC 1794

Query: 470  YDTYGGFVCACQP 508
            Y+T G + C C P
Sbjct: 1795 YNTVGNYTCICPP 1807



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+      RNC TD+DEC  +      G+CV+   ++ C C     +G+   +  
Sbjct: 1184 CRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1242

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +++EC+ D  LC  GVC++T G + C C P
Sbjct: 1243 MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1273



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCET 418
            C+CP GY     GR+C+ D+DEC+          CV+ +  +TC C   G+T     C  
Sbjct: 2599 CSCPKGYILQEDGRSCK-DLDECATKQHNCQF-LCVNTIGGFTCKCPP-GFTQHHTSCID 2655

Query: 419  NVNECEEDRALCGH-GVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            N NEC  D  LCG  G+C +T G F C CQ   +   T + C  V
Sbjct: 2656 N-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2699



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257  CTCPPGYT--GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C CP GYT  G  C  D DECS    C NG  C + +  + C C      G    CE ++
Sbjct: 2282 CECPFGYTLAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DI 2338

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC ++  LC    C +TYG + C C
Sbjct: 2339 NECAQNPLLCAFR-CVNTYGSYECKC 2363



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
            C C PGY  T      D +EC       + G+C+D V ++ C C  TG+     +T   +
Sbjct: 1964 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCH-TGFKTNDDQTMCLD 2022

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            +NECE D   CG+G C +T G F C C
Sbjct: 2023 INECERDA--CGNGTCRNTIGSFNCRC 2047



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+     G+NCE D+DECS    CLNG  C++   ++ C C         G  C+
Sbjct: 686 CVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK 743

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            ++NECE    +C +G C +T G + C C P
Sbjct: 744 -DINECETP-GICMNGRCVNTDGSYRCECFP 772



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  GY       +NC  D+DEC        GG C +   +Y C+C             
Sbjct: 1226 CKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1284

Query: 419  -NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NECE    LC +G C +  G + CAC P
Sbjct: 1285 IDINECELSAHLCPNGRCVNLIGKYQCACNP 1315



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTGR---NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA----TGYTGARCE 415
            C+CP GY      N   D +EC  A  C  G  C + + +Y C C A      ++G  C+
Sbjct: 2721 CSCPQGYLQHYQWNQCVDENECLSAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG-CQ 2778

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NEC   +A C +G C +T GG++C C P
Sbjct: 2779 -DINECGSAQAPCSYG-CSNTEGGYLCGCPP 2807



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCET 418
           C C  GY      T   D+DEC       N GRC++   ++ C C A  +    G  CE 
Sbjct: 644 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE- 702

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           +++EC   R +C +G+C +  G F C C+P
Sbjct: 703 DMDEC-SIRNMCLNGMCINEDGSFKCICKP 731



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETN 421
            LC+  PG T     +D++EC+        G C +    Y C C + GY    TG  C  +
Sbjct: 841  LCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS-GYEVDSTGKNC-VD 896

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            +NEC  +  LC +G C +T G FVC C
Sbjct: 897  INECVLNSLLCDNGQCRNTPGSFVCTC 923



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  G+      + C  DV+EC      CL+G  C +   ++ C C   GY+G + +T 
Sbjct: 1394 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDM-GYSGKKGKTG 1450

Query: 419  --NVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
              ++NECE     CG H VC +T G F C+C P   G
Sbjct: 1451 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1487



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
           DVDEC        GG C++ V ++ C C A         +CE +++EC     +C  G C
Sbjct: 377 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGEC 435

Query: 470 YDTYGGFVCACQPATPGS-TATGCRRVR 550
            +T   + C C P    S   T C  VR
Sbjct: 436 TNTVSSYFCKCPPGFYTSPDGTRCIDVR 463



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
           C C  G+    R    DVDEC        GG C++   +YTC C A GY      T   +
Sbjct: 605 CECNKGFQLDLRGECIDVDECEKNPCA--GGECINNQGSYTCQCRA-GYQSTLTRTECRD 661

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           ++EC ++  +C +G C +T G F C C
Sbjct: 662 IDECLQNGRICNNGRCINTDGSFHCVC 688



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 37/103 (35%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
            C C  G+     G+ CE D+DECS    C+ G  C +    + C+C   GY    +G  C
Sbjct: 1560 CECDMGFVPSADGKACE-DIDECSLPNICVFG-TCHNLPGLFRCECEI-GYELDRSGGNC 1616

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
             T+VNEC  D   C  G C +T G ++C C P      T  GC
Sbjct: 1617 -TDVNECL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGC 1657



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNECEEDRALCGHGVCYD 475
            D+DEC     C +G +C++   +Y C+C   GYT A  E  + +EC      CG+G C +
Sbjct: 2258 DMDECKEPDVCKHG-QCINTDGSYRCECPF-GYTLAGNECVDTDECSVGNP-CGNGTCKN 2314

Query: 476  TYGGFVCACQPA-TPGSTATGCRRVRQ 553
              GGF C C+    PG   T C  + +
Sbjct: 2315 VIGGFECTCEEGFEPGPMMT-CEDINE 2340



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+    TG +CE DVDEC G   C +G  C + +  Y C C       Y   +C 
Sbjct: 2681 CECQRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQC- 2736

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             + NEC     +CG   C++T G + C C
Sbjct: 2737 VDENECLSAH-ICGGASCHNTLGSYKCMC 2764



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
            C C  GY     GR C  D++EC         G C +   +Y C C   GY+    +CE 
Sbjct: 2087 CQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPP-GYSLQNEKCE- 2143

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRVR 550
            +++EC E+  +C  G C +T G F C C +  +  S+   C+ +R
Sbjct: 2144 DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLR 2188



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C C  GY    TG+NC  D++EC   +   + G+C +   ++ C C          +T  
Sbjct: 879  CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 937

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
            +++ECE     C +GVC ++ G F+C C   +T   T T C
Sbjct: 938  DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTIC 976



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257  CTCPPGYT-GRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---T 418
            C CPPG+    N     D++EC  +A     GRCV+ +  Y C C   GY          
Sbjct: 1269 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCV 1327

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC      C    C ++ G + C+CQP
Sbjct: 1328 DIDECSIMNGGC-ETFCTNSEGSYECSCQP 1356



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNE 430
            CP G        D+DEC         G CV+   +Y C C  TGY    TG  C  ++NE
Sbjct: 2521 CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCIC-KTGYTPDITGTSC-VDLNE 2578

Query: 431  CEEDRALCGHGVCYDTYGGFVCAC 502
            C +    C   +C +T G + C+C
Sbjct: 2579 CNQAPKPCNF-ICKNTEGSYQCSC 2601



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
 Frame = +2

Query: 254  LCTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGA 406
            LC   PG+       G+    D++EC    +    G+C + + ++ C C  +G+   +  
Sbjct: 1138 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD-SGFALDSEE 1196

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            R  T+++EC     LCG G C +T G F C C
Sbjct: 1197 RNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1228



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECS-GAAACLNGG-RCVDAVNNYTCDCTATGYT----GA 406
            C CP GY  R     C+ D DEC  G   C      C + +  Y C C   GY     G 
Sbjct: 2361 CKCPVGYVLREDRRMCK-DEDECEEGKHDCTEKQMECKNLIGTYMCIC-GPGYQRRPDGE 2418

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             C  + NEC+    +C +G C +T G + C C
Sbjct: 2419 GC-VDENECQTKPGICENGRCLNTRGSYTCEC 2449



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 30/80 (37%), Positives = 38/80 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GY G +C   V E    + CLNGGRCV A N   C CT  G+TG +CE +     
Sbjct: 265 CLCQKGYIGTHCGQPVCE----SGCLNGGRCV-APNR--CACT-YGFTGPQCERDY-RTG 315

Query: 437 EDRALCGHGVCYDTYGGFVC 496
               +  + +C     G VC
Sbjct: 316 PCFTVISNQMCQGQLSGIVC 335



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
           C CP G+      + CE D+DECS       GG C + V++Y C C    YT   G RC
Sbjct: 402 CKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 459



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  GYT    G +C  D++EC+ A    N   C +   +Y C C   GY     G  C
Sbjct: 2558 CICKTGYTPDITGTSC-VDLNECNQAPKPCNF-ICKNTEGSYQCSCPK-GYILQEDGRSC 2614

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            + +++EC   +  C   +C +T GGF C C P
Sbjct: 2615 K-DLDECATKQHNCQF-LCVNTIGGFTCKCPP 2644



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = +2

Query: 275  YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDR 445
            YTG     D+DEC         G C++ V ++ C+C    +   +   CE +++EC+   
Sbjct: 1891 YTG--LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGP 1947

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
                +  C +T G + C C+P
Sbjct: 1948 VCQRNAECINTAGSYRCDCKP 1968



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNECEEDRALCGHGVCYDTY 481
           D C         GRC+    +Y C+C        R E  +V+ECE++   C  G C +  
Sbjct: 582 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQ 639

Query: 482 GGFVCACQPATPGS-TATGCRRV 547
           G + C C+     + T T CR +
Sbjct: 640 GSYTCQCRAGYQSTLTRTECRDI 662



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NV 424
            C C  G+   + +T   D++EC    AC NG  C + + ++ C C          +  +V
Sbjct: 2005 CLCHTGFKTNDDQTMCLDINECE-RDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDV 2062

Query: 425  NECEEDRA-LCGHGVCYDTYGGFVCAC 502
            +EC      LC +G C +T G F C C
Sbjct: 2063 DECASGNGNLCRNGQCINTVGSFQCQC 2089



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 24/83 (28%), Positives = 37/83 (44%)
 Frame = +2

Query: 287  NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            N  T   +C  +     G  C     +  C    +   G +CE +++ECE    +C +G+
Sbjct: 998  NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGL 1056

Query: 467  CYDTYGGFVCACQPATPGSTATG 535
            C +T G F C C P+     ATG
Sbjct: 1057 CVNTRGSFKCQC-PSGMTLDATG 1078



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY----HGTYC 164
            Y C C   YTG+       D C+     C +G +C+ +  G Y C+C  G+     G  C
Sbjct: 1518 YRCLCKEGYTGDGFTCTDLDECSENLNLCGNG-QCL-NAPGGYRCECDMGFVPSADGKAC 1575

Query: 165  EL--EVSLDPLCVAGPCRN 215
            E   E SL  +CV G C N
Sbjct: 1576 EDIDECSLPNICVFGTCHN 1594



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/60 (33%), Positives = 25/60 (41%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C    G P   + C +G RCV   R    C C  G+ G  CE +    P
Sbjct: 265 CLCQKGYIGTHC----GQPVCESGCLNGGRCVAPNR----CACTYGFTGPQCERDYRTGP 316



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +3

Query: 60   DPCASA-ACRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSCS 230
            D C     C+HG +C+    G Y C+CP GY   G  C   V  D   V  PC  NG+C 
Sbjct: 2260 DECKEPDVCKHG-QCINTD-GSYRCECPFGYTLAGNEC---VDTDECSVGNPC-GNGTCK 2313

Query: 231  VPPGG 245
               GG
Sbjct: 2314 NVIGG 2318



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
 Frame = +3

Query: 36  NNCEVDAGD---PCASAACRH-GARCVEDGR-GDYSCDCPPGYHGTYCELEVSLDPLCVA 200
           N C   +G     C S + +H   RC+  G   D  C C  GY GT+C       P+C +
Sbjct: 229 NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCG-----QPVCES 283

Query: 201 GPCRNNGSCSVP 236
           G C N G C  P
Sbjct: 284 G-CLNGGRCVAP 294



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV- 176
           Y C C   +  +   E    D C    C  G  C+ + +G Y+C C  GY  T    E  
Sbjct: 603 YRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINN-QGSYTCQCRAGYQSTLTRTECR 660

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D     G   NNG C
Sbjct: 661 DIDECLQNGRICNNGRC 677



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 5/86 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHG---TYCE 167
            ++C C+  + G+  +    D C++    C   A C ++  G Y C C  GY G   T  +
Sbjct: 1477 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC-KNTMGSYRCLCKEGYTGDGFTCTD 1535

Query: 168  LEVSLDPLCVAGPCRNNGSCSVPPGG 245
            L+   + L + G    NG C   PGG
Sbjct: 1536 LDECSENLNLCG----NGQCLNAPGG 1557



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNC-ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP G    +C    +  C+    C+NGG C D      C C   GY G  C   V E
Sbjct: 230 MCTCPSGQIAPSCGSRSIQHCN--IRCMNGGSCSDD----HCLC-QKGYIGTHCGQPVCE 282

Query: 431 --CEEDRALCGHGVCYDTYG 484
             C           C  TYG
Sbjct: 283 SGCLNGGRCVAPNRCACTYG 302



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNN----CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            + C C   +  N+    CE D  +      C+  A C+    G Y CDC PGY  T
Sbjct: 1920 FRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTA-GSYRCDCKPGYRFT 1973



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY--- 161
            + C C   +    TG++CE D  +   +  C+HG + +  G   Y C CP GY   Y   
Sbjct: 2679 FTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHGCQNIIGG---YRCSCPQGYLQHYQWN 2734

Query: 162  -C--ELEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             C  E E     +C    C N  GS  C  P G
Sbjct: 2735 QCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2767



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            ++C C   Y     G  C VD  + C     +      ++  G Y C CPPGY      C
Sbjct: 2085 FQCQCNEGYEVAPDGRTC-VDINE-CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC 2142

Query: 165  E--LEVSLDP-LCVAGPCRN-NGS--CSVPPGGDTYSAPVR-QDTRV 284
            E   E   +P +C  G C N  GS  C  P G    S+  R QD R+
Sbjct: 2143 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 2189



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            ++C C + +  ++ E +  D   C  +   C  G +CV    GD+ C C  GY   +  +
Sbjct: 1182 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTP-GDFECKCDEGYESGFMMM 1239

Query: 171  -------EVSLDP-LCVAGPCRN-NGS--CSVPPG 242
                   E   DP LC  G C N  GS  C  PPG
Sbjct: 1240 KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 1274



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +++EC+    +C +G C +  G + C C+   TP  T T C
Sbjct: 2533 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2573



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            Y+C C   Y     G +C+ D  D CA+        CV    G ++C CPPG+  H T C
Sbjct: 2597 YQCSCPKGYILQEDGRSCK-DL-DECATKQHNCQFLCVNT-IGGFTCKCPPGFTQHHTSC 2653

Query: 165  --ELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
                E + D       C + G C   PG  T
Sbjct: 2654 IDNNECTSD----INLCGSKGICQNTPGSFT 2680



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            + C C   Y    +G NC  D  +      C  G  CV    G Y CDCPP +
Sbjct: 1599 FRCECEIGYELDRSGGNC-TDVNECLDPTTCISG-NCVNTP-GSYICDCPPDF 1648



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTA----RYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C       Y  N C VD  + C SA    GA C  +  G Y C CP G+
Sbjct: 2719 YRCSCPQGYLQHYQWNQC-VDENE-CLSAHICGGASC-HNTLGSYKCMCPAGF 2768



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y+C C A +        C+       A A C +G    E G   Y C CPPGY
Sbjct: 2760 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGG---YLCGCPPGY 2809



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGD--PCASAACRHGARCV-EDGRGDYSCDCPPGYHG 155
            CHC   Y+G   +    D   C   A   G   V  +  G + C C PG+ G
Sbjct: 1436 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1487



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 27/63 (42%), Positives = 31/63 (49%), Gaps = 9/63 (14%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGY----HGTYC-EL-EVSLDPLCVAGPCRN-NGS--CSV 233
            CR+G  CV D RG Y C C  GY     GT C +L E +  P      C+N  GS  CS 
Sbjct: 2544 CRNG-ECVND-RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSC 2601

Query: 234  PPG 242
            P G
Sbjct: 2602 PKG 2604



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            N CE+ A        C +G RCV +  G Y C C PGYH T
Sbjct: 1288 NECELSAH------LCPNG-RCV-NLIGKYQCACNPGYHST 1320



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C   YT    G +C VD  + C  A       C ++  G Y C CP GY
Sbjct: 2556 YHCICKTGYTPDITGTSC-VDLNE-CNQAPKPCNFIC-KNTEGSYQCSCPKGY 2605


>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
          Length = 2871

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-TDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
            C+C PG+ G   + TD+DECS G   C     C + + +Y C C   GYTG     T+++
Sbjct: 1348 CSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE-GYTGDGFTCTDLD 1406

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            EC E+  LCG+G C +  GG+ C C     P +    C  +
Sbjct: 1407 ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCE 415
            C CP G+   +    CE D+DEC     C     C++   +Y CDC   GY   +  +C 
Sbjct: 1791 CECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKP-GYRFTSTGQCN 1848

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
               NEC+E   +C HG C DT G F C C
Sbjct: 1849 DR-NECQEIPNICSHGQCIDTVGSFYCLC 1876



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C+C PG+      R+C TD+DEC       +GG+C +    Y C C          +T  
Sbjct: 1221 CSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 1279

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA-TGCRRVRQ 553
            +VNEC+ +  +C  G C +T G F+C C     G    TGC  + +
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEEDRALCGHGVC 469
            D+DEC        GG+C++   ++ C C  TGY      R   +VNECE    +CG G C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETP-GICGPGTC 1663

Query: 470  YDTYGGFVCACQP 508
            Y+T G + C C P
Sbjct: 1664 YNTVGNYTCICPP 1676



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+      RNC TD+DEC  +      G+CV+   ++ C C     +G+   +  
Sbjct: 1053 CRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1111

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +++EC+ D  LC  GVC++T G + C C P
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCET 418
            C+CP GY     GR+C+ D+DEC+          CV+ +  +TC C   G+T     C  
Sbjct: 2468 CSCPKGYILQEDGRSCK-DLDECATKQHNCQF-LCVNTIGGFTCKCPP-GFTQHHTSCID 2524

Query: 419  NVNECEEDRALCGH-GVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            N NEC  D  LCG  G+C +T G F C CQ   +   T + C  V
Sbjct: 2525 N-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257  CTCPPGYT--GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C CP GYT  G  C  D DECS    C NG  C + +  + C C      G    CE ++
Sbjct: 2151 CECPFGYTLAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DI 2207

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC ++  LC    C +TYG + C C
Sbjct: 2208 NECAQNPLLCAFR-CVNTYGSYECKC 2232



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
            C C PGY  T      D +EC       + G+C+D V ++ C C  TG+     +T   +
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCH-TGFKTNDDQTMCLD 1891

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            +NECE D   CG+G C +T G F C C
Sbjct: 1892 INECERDA--CGNGTCRNTIGSFNCRC 1916



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+     G+NCE D+DECS    CLNG  C++   ++ C C         G  C+
Sbjct: 555 CVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK 612

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            ++NECE    +C +G C +T G + C C P
Sbjct: 613 -DINECETP-GICMNGRCVNTDGSYRCECFP 641



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  GY       +NC  D+DEC        GG C +   +Y C+C             
Sbjct: 1095 CKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153

Query: 419  -NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NECE    LC +G C +  G + CAC P
Sbjct: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNP 1184



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTGR---NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA----TGYTGARCE 415
            C+CP GY      N   D +EC  A  C  G  C + + +Y C C A      ++G  C+
Sbjct: 2590 CSCPQGYLQHYQWNQCVDENECLSAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG-CQ 2647

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NEC   +A C +G C +T GG++C C P
Sbjct: 2648 -DINECGSAQAPCSYG-CSNTEGGYLCGCPP 2676



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCET 418
           C C  GY      T   D+DEC       N GRC++   ++ C C A  +    G  CE 
Sbjct: 513 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE- 571

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           +++EC   R +C +G+C +  G F C C+P
Sbjct: 572 DMDEC-SIRNMCLNGMCINEDGSFKCICKP 600



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETN 421
           LC+  PG T     +D++EC+        G C +    Y C C + GY    TG  C  +
Sbjct: 710 LCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS-GYEVDSTGKNC-VD 765

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  LC +G C +T G FVC C
Sbjct: 766 INECVLNSLLCDNGQCRNTPGSFVCTC 792



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  G+      + C  DV+EC      CL+G  C +   ++ C C   GY+G + +T 
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDM-GYSGKKGKTG 1319

Query: 419  --NVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
              ++NECE     CG H VC +T G F C+C P   G
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
           DVDEC        GG C++ V ++ C C A         +CE +++EC     +C  G C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGEC 304

Query: 470 YDTYGGFVCACQPATPGS-TATGCRRVR 550
            +T   + C C P    S   T C  VR
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCIDVR 332



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
           C C  G+    R    DVDEC        GG C++   +YTC C A GY      T   +
Sbjct: 474 CECNKGFQLDLRGECIDVDECEKNPCA--GGECINNQGSYTCQCRA-GYQSTLTRTECRD 530

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           ++EC ++  +C +G C +T G F C C
Sbjct: 531 IDECLQNGRICNNGRCINTDGSFHCVC 557



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 37/103 (35%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
            C C  G+     G+ CE D+DECS    C+ G  C +    + C+C   GY    +G  C
Sbjct: 1429 CECDMGFVPSADGKACE-DIDECSLPNICVFG-TCHNLPGLFRCECEI-GYELDRSGGNC 1485

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
             T+VNEC  D   C  G C +T G ++C C P      T  GC
Sbjct: 1486 -TDVNECL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGC 1526



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNECEEDRALCGHGVCYD 475
            D+DEC     C +G +C++   +Y C+C   GYT A  E  + +EC      CG+G C +
Sbjct: 2127 DMDECKEPDVCKHG-QCINTDGSYRCECPF-GYTLAGNECVDTDECSVGNP-CGNGTCKN 2183

Query: 476  TYGGFVCACQPA-TPGSTATGCRRVRQ 553
              GGF C C+    PG   T C  + +
Sbjct: 2184 VIGGFECTCEEGFEPGPMMT-CEDINE 2209



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+    TG +CE DVDEC G   C +G  C + +  Y C C       Y   +C 
Sbjct: 2550 CECQRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQC- 2605

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             + NEC     +CG   C++T G + C C
Sbjct: 2606 VDENECLSAH-ICGGASCHNTLGSYKCMC 2633



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
            C C  GY     GR C  D++EC         G C +   +Y C C   GY+    +CE 
Sbjct: 1956 CQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPP-GYSLQNEKCE- 2012

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRVR 550
            +++EC E+  +C  G C +T G F C C +  +  S+   C+ +R
Sbjct: 2013 DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLR 2057



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C C  GY    TG+NC  D++EC   +   + G+C +   ++ C C          +T  
Sbjct: 748  CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
            +++ECE     C +GVC ++ G F+C C   +T   T T C
Sbjct: 807  DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTIC 845



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257  CTCPPGYT-GRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---T 418
            C CPPG+    N     D++EC  +A     GRCV+ +  Y C C   GY          
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCV 1196

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC      C    C ++ G + C+CQP
Sbjct: 1197 DIDECSIMNGGC-ETFCTNSEGSYECSCQP 1225



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNE 430
            CP G        D+DEC         G CV+   +Y C C  TGY    TG  C  ++NE
Sbjct: 2390 CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCIC-KTGYTPDITGTSC-VDLNE 2447

Query: 431  CEEDRALCGHGVCYDTYGGFVCAC 502
            C +    C   +C +T G + C+C
Sbjct: 2448 CNQAPKPCNF-ICKNTEGSYQCSC 2470



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
 Frame = +2

Query: 254  LCTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGA 406
            LC   PG+       G+    D++EC    +    G+C + + ++ C C  +G+   +  
Sbjct: 1007 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD-SGFALDSEE 1065

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            R  T+++EC     LCG G C +T G F C C
Sbjct: 1066 RNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECS-GAAACLNGG-RCVDAVNNYTCDCTATGYT----GA 406
            C CP GY  R     C+ D DEC  G   C      C + +  Y C C   GY     G 
Sbjct: 2230 CKCPVGYVLREDRRMCK-DEDECEEGKHDCTEKQMECKNLIGTYMCIC-GPGYQRRPDGE 2287

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             C  + NEC+    +C +G C +T G + C C
Sbjct: 2288 GC-VDENECQTKPGICENGRCLNTRGSYTCEC 2318



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 31/83 (37%), Positives = 39/83 (46%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GY G +C   V E    + CLNGGRCV A N   C CT  G+TG +CE +     
Sbjct: 134 CLCQKGYIGTHCGQPVCE----SGCLNGGRCV-APNR--CACT-YGFTGPQCERDY-RTG 184

Query: 437 EDRALCGHGVCYDTYGGFVCACQ 505
               +  + +C     G VC  Q
Sbjct: 185 PCFTVISNQMCQGQLSGIVCTKQ 207



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
           C CP G+      + CE D+DECS       GG C + V++Y C C    YT   G RC
Sbjct: 271 CKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  GYT    G +C  D++EC+ A    N   C +   +Y C C   GY     G  C
Sbjct: 2427 CICKTGYTPDITGTSC-VDLNECNQAPKPCNF-ICKNTEGSYQCSCPK-GYILQEDGRSC 2483

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            + +++EC   +  C   +C +T GGF C C P
Sbjct: 2484 K-DLDECATKQHNCQF-LCVNTIGGFTCKCPP 2513



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = +2

Query: 275  YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDR 445
            YTG     D+DEC         G C++ V ++ C+C    +   +   CE +++EC+   
Sbjct: 1760 YTG--LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGP 1816

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
                +  C +T G + C C+P
Sbjct: 1817 VCQRNAECINTAGSYRCDCKP 1837



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVNECEEDRALCGHGVCYDTY 481
           D C         GRC+    +Y C+C        R E  +V+ECE++   C  G C +  
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQ 508

Query: 482 GGFVCACQPATPGS-TATGCRRV 547
           G + C C+     + T T CR +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDI 531



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NV 424
            C C  G+   + +T   D++EC    AC NG  C + + ++ C C          +  +V
Sbjct: 1874 CLCHTGFKTNDDQTMCLDINECE-RDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDV 1931

Query: 425  NECEEDRA-LCGHGVCYDTYGGFVCAC 502
            +EC      LC +G C +T G F C C
Sbjct: 1932 DECASGNGNLCRNGQCINTVGSFQCQC 1958



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 24/83 (28%), Positives = 37/83 (44%)
 Frame = +2

Query: 287  NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            N  T   +C  +     G  C     +  C    +   G +CE +++ECE    +C +G+
Sbjct: 867  NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGL 925

Query: 467  CYDTYGGFVCACQPATPGSTATG 535
            C +T G F C C P+     ATG
Sbjct: 926  CVNTRGSFKCQC-PSGMTLDATG 947



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY----HGTYC 164
            Y C C   YTG+       D C+     C +G +C+ +  G Y C+C  G+     G  C
Sbjct: 1387 YRCLCKEGYTGDGFTCTDLDECSENLNLCGNG-QCL-NAPGGYRCECDMGFVPSADGKAC 1444

Query: 165  EL--EVSLDPLCVAGPCRN 215
            E   E SL  +CV G C N
Sbjct: 1445 EDIDECSLPNICVFGTCHN 1463



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/60 (33%), Positives = 25/60 (41%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C    G P   + C +G RCV   R    C C  G+ G  CE +    P
Sbjct: 134 CLCQKGYIGTHC----GQPVCESGCLNGGRCVAPNR----CACTYGFTGPQCERDYRTGP 185



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +3

Query: 60   DPCASA-ACRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSCS 230
            D C     C+HG +C+    G Y C+CP GY   G  C   V  D   V  PC  NG+C 
Sbjct: 2129 DECKEPDVCKHG-QCINTD-GSYRCECPFGYTLAGNEC---VDTDECSVGNPC-GNGTCK 2182

Query: 231  VPPGG 245
               GG
Sbjct: 2183 NVIGG 2187



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
 Frame = +3

Query: 36  NNCEVDAGD---PCASAACRH-GARCVEDGR-GDYSCDCPPGYHGTYCELEVSLDPLCVA 200
           N C   +G     C S + +H   RC+  G   D  C C  GY GT+C       P+C +
Sbjct: 98  NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCG-----QPVCES 152

Query: 201 GPCRNNGSCSVP 236
           G C N G C  P
Sbjct: 153 G-CLNGGRCVAP 163



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV- 176
           Y C C   +  +   E    D C    C  G  C+ + +G Y+C C  GY  T    E  
Sbjct: 472 YRCECNKGFQLDLRGECIDVDECEKNPCA-GGECINN-QGSYTCQCRAGYQSTLTRTECR 529

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D     G   NNG C
Sbjct: 530 DIDECLQNGRICNNGRC 546



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 5/86 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHG---TYCE 167
            ++C C+  + G+  +    D C++    C   A C ++  G Y C C  GY G   T  +
Sbjct: 1346 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC-KNTMGSYRCLCKEGYTGDGFTCTD 1404

Query: 168  LEVSLDPLCVAGPCRNNGSCSVPPGG 245
            L+   + L + G    NG C   PGG
Sbjct: 1405 LDECSENLNLCG----NGQCLNAPGG 1426



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNC-ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP G    +C    +  C+    C+NGG C D      C C   GY G  C   V E
Sbjct: 99  MCTCPSGQIAPSCGSRSIQHCN--IRCMNGGSCSDD----HCLC-QKGYIGTHCGQPVCE 151

Query: 431 --CEEDRALCGHGVCYDTYG 484
             C           C  TYG
Sbjct: 152 SGCLNGGRCVAPNRCACTYG 171



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNN----CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            + C C   +  N+    CE D  +      C+  A C+    G Y CDC PGY  T
Sbjct: 1789 FRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTA-GSYRCDCKPGYRFT 1842



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY--- 161
            + C C   +    TG++CE D  +   +  C+HG + +  G   Y C CP GY   Y   
Sbjct: 2548 FTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHGCQNIIGG---YRCSCPQGYLQHYQWN 2603

Query: 162  -C--ELEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             C  E E     +C    C N  GS  C  P G
Sbjct: 2604 QCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2636



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            ++C C   Y     G  C VD  + C     +      ++  G Y C CPPGY      C
Sbjct: 1954 FQCQCNEGYEVAPDGRTC-VDINE-CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC 2011

Query: 165  E--LEVSLDP-LCVAGPCRN-NGS--CSVPPGGDTYSAPVR-QDTRV 284
            E   E   +P +C  G C N  GS  C  P G    S+  R QD R+
Sbjct: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 2058



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            ++C C + +  ++ E +  D   C  +   C  G +CV    GD+ C C  GY   +  +
Sbjct: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTP-GDFECKCDEGYESGFMMM 1108

Query: 171  -------EVSLDP-LCVAGPCRN-NGS--CSVPPG 242
                   E   DP LC  G C N  GS  C  PPG
Sbjct: 1109 KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 1143



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +++EC+    +C +G C +  G + C C+   TP  T T C
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            Y+C C   Y     G +C+ D  D CA+        CV    G ++C CPPG+  H T C
Sbjct: 2466 YQCSCPKGYILQEDGRSCK-DL-DECATKQHNCQFLCVNT-IGGFTCKCPPGFTQHHTSC 2522

Query: 165  --ELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
                E + D       C + G C   PG  T
Sbjct: 2523 IDNNECTSD----INLCGSKGICQNTPGSFT 2549



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            + C C   Y    +G NC  D  +      C  G  CV    G Y CDCPP +
Sbjct: 1468 FRCECEIGYELDRSGGNC-TDVNECLDPTTCISG-NCVNTP-GSYICDCPPDF 1517



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTA----RYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C       Y  N C VD  + C SA    GA C  +  G Y C CP G+
Sbjct: 2588 YRCSCPQGYLQHYQWNQC-VDENE-CLSAHICGGASC-HNTLGSYKCMCPAGF 2637



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y+C C A +        C+       A A C +G    E G   Y C CPPGY
Sbjct: 2629 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGG---YLCGCPPGY 2678



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGD--PCASAACRHGARCV-EDGRGDYSCDCPPGYHG 155
            CHC   Y+G   +    D   C   A   G   V  +  G + C C PG+ G
Sbjct: 1305 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 27/63 (42%), Positives = 31/63 (49%), Gaps = 9/63 (14%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGY----HGTYC-EL-EVSLDPLCVAGPCRN-NGS--CSV 233
            CR+G  CV D RG Y C C  GY     GT C +L E +  P      C+N  GS  CS 
Sbjct: 2413 CRNG-ECVND-RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSC 2470

Query: 234  PPG 242
            P G
Sbjct: 2471 PKG 2473



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            N CE+ A        C +G RCV +  G Y C C PGYH T
Sbjct: 1157 NECELSAH------LCPNG-RCV-NLIGKYQCACNPGYHST 1189



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C   YT    G +C VD  + C  A       C ++  G Y C CP GY
Sbjct: 2425 YHCICKTGYTPDITGTSC-VDLNE-CNQAPKPCNFIC-KNTEGSYQCSCPKGY 2474


>BX640729-1|CAE45845.1|  674|Homo sapiens hypothetical protein
           protein.
          Length = 674

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 544 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 600

Query: 437 EDRALCGHG-VCYDTYGGFVCAC 502
             +  C +G  C     G+ C C
Sbjct: 601 SHQ--CANGATCISHTNGYSCLC 621



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
           CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 581 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 638

Query: 422 VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
           V   E+    C   G C +      C C+P   G
Sbjct: 639 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 529 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 585

Query: 509 ATPG 520
              G
Sbjct: 586 GYTG 589



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 579 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 634

Query: 183 DPLCVAGPCRNNGSC 227
            P  V G  + N +C
Sbjct: 635 LPSTVCGNEKTNLTC 649



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 542 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 597

Query: 183 DPLCVAGPCRNNGSC 227
              C +  C N  +C
Sbjct: 598 --NCQSHQCANGATC 610



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 524 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 573



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 267 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 320



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 277 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 332

Query: 506 PATPGST 526
               G +
Sbjct: 333 AVFNGQS 339



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 41  SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 88


>AL136322-1|CAI16644.1|  674|Homo sapiens crumbs homolog 1
           (Drosophila) protein.
          Length = 674

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+CP G++G++CE ++DEC  +  C++ G C D V  Y C C   GYTG  CE +++ C+
Sbjct: 544 CSCPLGWSGKHCELNIDECF-SNPCIH-GNCSDRVAAYHCTC-EPGYTGVNCEVDIDNCQ 600

Query: 437 EDRALCGHG-VCYDTYGGFVCAC 502
             +  C +G  C     G+ C C
Sbjct: 601 SHQ--CANGATCISHTNGYSCLC 621



 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-----TN 421
           CTC PGYTG NCE D+D C  +  C NG  C+   N Y+C C    +TG  C      + 
Sbjct: 581 CTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFG-NFTGKFCRQSRLPST 638

Query: 422 VNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
           V   E+    C   G C +      C C+P   G
Sbjct: 639 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTG 672



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 25/64 (39%), Positives = 35/64 (54%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           CL+GG C D  ++Y C C   G++G  CE N++EC  +   C HG C D    + C C+P
Sbjct: 529 CLHGGNCEDIYSSYHCSC-PLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEP 585

Query: 509 ATPG 520
              G
Sbjct: 586 GYTG 589



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/75 (41%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   YTG NCEVD  D C S  C +GA C+    G YSC C   + G +C    S 
Sbjct: 579 YHCTCEPGYTGVNCEVDI-DNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFC--RQSR 634

Query: 183 DPLCVAGPCRNNGSC 227
            P  V G  + N +C
Sbjct: 635 LPSTVCGNEKTNLTC 649



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 27/75 (36%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   ++G +CE++  D C S  C HG  C  D    Y C C PGY G  CE+++  
Sbjct: 542 YHCSCPLGWSGKHCELNI-DECFSNPCIHG-NC-SDRVAAYHCTCEPGYTGVNCEVDID- 597

Query: 183 DPLCVAGPCRNNGSC 227
              C +  C N  +C
Sbjct: 598 --NCQSHQCANGATC 610



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCS 230
           C S  C HG  C ED    Y C CP G+ G +CEL +     C + PC  +G+CS
Sbjct: 524 CNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNID---ECFSNPC-IHGNCS 573



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
 Frame = +3

Query: 54  AGD-PCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           AGD  C S  C +G  C      D+SC CP    G  CE EV     C   PC +   C
Sbjct: 267 AGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQ---WCGFSPCPHGAQC 320



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQ 505
           C NGG C    ++++C C A   +G  CE  V  C    + C HG  C     GF C   
Sbjct: 277 CHNGGVCHSRWDDFSCSCPAL-TSGKACE-EVQWC--GFSPCPHGAQCQPVLQGFECIAN 332

Query: 506 PATPGST 526
               G +
Sbjct: 333 AVFNGQS 339



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
 Frame = +3

Query: 30  TGNNCEVDAG----DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           +G++  V AG    D C S  C+   RC+      Y CDC   Y G  C
Sbjct: 41  SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLS-YQCDCHRPYEGPNC 88


>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
          Length = 2871

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE-TDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
            C+C PG+ G   + TD+DECS G   C     C + + +Y C C   GYTG     T+++
Sbjct: 1348 CSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE-GYTGDGFTCTDLD 1406

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            EC E+  LCG+G C +  GG+ C C     P +    C  +
Sbjct: 1407 ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDI 1447



 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCE 415
            C CP G+   +    CE D+DEC     C     C++   +Y CDC   GY   +  +C 
Sbjct: 1791 CECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKP-GYRFTSTGQCN 1848

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
               NEC+E   +C HG C DT G F C C
Sbjct: 1849 DR-NECQEIPNICSHGQCIDTVGSFYCLC 1876



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C+C PG+      R+C TD+DEC       +GG+C +    Y C C          +T  
Sbjct: 1221 CSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 1279

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA-TGCRRVRQ 553
            +VNEC+ +  +C  G C +T G F+C C     G    TGC  + +
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEEDRALCGHGVC 469
            D+DEC        GG+C++   ++ C C  TGY      R   +VNECE    +CG G C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETP-GICGPGTC 1663

Query: 470  YDTYGGFVCACQP 508
            Y+T G + C C P
Sbjct: 1664 YNTVGNYTCICPP 1676



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+      RNC TD+DEC  +      G+CV+   ++ C C     +G+   +  
Sbjct: 1053 CRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1111

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +++EC+ D  LC  GVC++T G + C C P
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCET 418
            C+CP GY     GR+C+ D+DEC+          CV+ +  +TC C   G+T     C  
Sbjct: 2468 CSCPKGYILQEDGRSCK-DLDECATKQHNCQF-LCVNTIGGFTCKCPP-GFTQHHTSCID 2524

Query: 419  NVNECEEDRALCGH-GVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            N NEC  D  LCG  G+C +T G F C CQ   +   T + C  V
Sbjct: 2525 N-NECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
            C C PGY  T      D +EC       + G+C+D V ++ C C  TG+     +T   +
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCH-TGFKTNDDQTMCLD 1891

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            +NECE D   CG+G C +T G F C C
Sbjct: 1892 INECERDA--CGNGTCRNTIGSFNCRC 1916



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C CP GY   G  C  D DECS    C NG  C + +  + C C      G    CE ++
Sbjct: 2151 CECPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DI 2207

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            NEC ++  LC    C +TYG + C C
Sbjct: 2208 NECAQNPLLCAFR-CVNTYGSYECKC 2232



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+     G+NCE D+DECS    CLNG  C++   ++ C C         G  C+
Sbjct: 555 CVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK 612

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            ++NECE    +C +G C +T G + C C P
Sbjct: 613 -DINECETP-GICMNGRCVNTDGSYRCECFP 641



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  GY       +NC  D+DEC        GG C +   +Y C+C             
Sbjct: 1095 CKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153

Query: 419  -NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NECE    LC +G C +  G + CAC P
Sbjct: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNP 1184



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCET 418
           C C  GY      T   D+DEC       N GRC++   ++ C C A  +    G  CE 
Sbjct: 513 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE- 571

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           +++EC   R +C +G+C +  G F C C+P
Sbjct: 572 DMDEC-SIRNMCLNGMCINEDGSFKCICKP 600



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETN 421
           LC+  PG T     +D++EC+        G C +    Y C C + GY    TG  C  +
Sbjct: 710 LCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS-GYEVDSTGKNC-VD 765

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  LC +G C +T G FVC C
Sbjct: 766 INECVLNSLLCDNGQCRNTPGSFVCTC 792



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  G+      + C  DV+EC      CL+G  C +   ++ C C   GY+G + +T 
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDM-GYSGKKGKTG 1319

Query: 419  --NVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
              ++NECE     CG H VC +T G F C+C P   G
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
           DVDEC        GG C++ V ++ C C A         +CE +++EC     +C  G C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGEC 304

Query: 470 YDTYGGFVCACQPATPGS-TATGCRRVR 550
            +T   + C C P    S   T C  VR
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCIDVR 332



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
           C C  G+    R    DVDEC        GG C++   +YTC C A GY      T   +
Sbjct: 474 CECNKGFQLDLRGECIDVDECEKNPCA--GGECINNQGSYTCQCRA-GYQSTLTRTECRD 530

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           ++EC ++  +C +G C +T G F C C
Sbjct: 531 IDECLQNGRICNNGRCINTDGSFHCVC 557



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 37/103 (35%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
            C C  G+     G+ CE D+DECS    C+ G  C +    + C+C   GY    +G  C
Sbjct: 1429 CECDMGFVPSADGKACE-DIDECSLPNICVFG-TCHNLPGLFRCECEI-GYELDRSGGNC 1485

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
             T+VNEC  D   C  G C +T G ++C C P      T  GC
Sbjct: 1486 -TDVNECL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGC 1526



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+    TG +CE DVDEC G   C +G  C + +  Y C C       Y   +C 
Sbjct: 2550 CECQRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQC- 2605

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             + NEC     +CG   C++T G + C C
Sbjct: 2606 VDENECLSAH-ICGGASCHNTLGSYKCMC 2633



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
            C C  GY     GR C  D++EC         G C +   +Y C C   GY+    +CE 
Sbjct: 1956 CQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPP-GYSLQNEKCE- 2012

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRVR 550
            +++EC E+  +C  G C +T G F C C +  +  S+   C+ +R
Sbjct: 2013 DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLR 2057



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTGR---NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA----TGYTGARCE 415
            C+CP GY      N   D +EC  A  C  G  C + + +Y C C A      ++G  C+
Sbjct: 2590 CSCPQGYLQHYQWNQCVDENECLSAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG-CQ 2647

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NEC   +A C +G   +T GG++C C P
Sbjct: 2648 -DINECGSAQAPCSYGSS-NTEGGYLCGCPP 2676



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGARCETNVNECEEDRALCGHGVCY 472
            D+DEC     C +G +C++   +Y C+C   GY   G  C  + +EC      CG+G C 
Sbjct: 2127 DMDECKEPDVCKHG-QCINTDGSYRCECPF-GYILAGNEC-VDTDECSVGNP-CGNGTCK 2182

Query: 473  DTYGGFVCACQPA-TPGSTATGCRRVRQ 553
            +  GGF C C+    PG   T C  + +
Sbjct: 2183 NVIGGFECTCEEGFEPGPMMT-CEDINE 2209



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C C  GY    TG+NC  D++EC   +   + G+C +   ++ C C          +T  
Sbjct: 748  CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
            +++ECE     C +GVC ++ G F+C C   +T   T T C
Sbjct: 807  DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTIC 845



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257  CTCPPGYT-GRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---T 418
            C CPPG+    N     D++EC  +A     GRCV+ +  Y C C   GY          
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCV 1196

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC      C    C ++ G + C+CQP
Sbjct: 1197 DIDECSIMNGGC-ETFCTNSEGSYECSCQP 1225



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNE 430
            CP G        D+DEC         G CV+   +Y C C  TGY    TG  C  ++NE
Sbjct: 2390 CPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCIC-KTGYTPDITGTSC-VDLNE 2447

Query: 431  CEEDRALCGHGVCYDTYGGFVCAC 502
            C +    C   +C +T G + C+C
Sbjct: 2448 CNQAPKPCNF-ICKNTEGSYQCSC 2470



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
 Frame = +2

Query: 254  LCTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGA 406
            LC   PG+       G+    D++EC    +    G+C + + ++ C C  +G+   +  
Sbjct: 1007 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD-SGFALDSEE 1065

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            R  T+++EC     LCG G C +T G F C C
Sbjct: 1066 RNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECS-GAAACLNGG-RCVDAVNNYTCDCTATGYT----GA 406
            C CP GY  R     C+ D DEC  G   C      C + +  Y C C   GY     G 
Sbjct: 2230 CKCPVGYVLREDRRMCK-DEDECEEGKHDCTEKQMECKNLIGTYMCIC-GPGYQRRPDGE 2287

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             C  + NEC+    +C +G C +T G + C C
Sbjct: 2288 GC-VDENECQTKPGICENGRCLNTRGSYTCEC 2318



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 30/80 (37%), Positives = 38/80 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GY G +C   V E    + CLNGGRCV A N   C CT  G+TG +CE +     
Sbjct: 134 CLCQKGYIGTHCGQPVCE----SGCLNGGRCV-APNR--CACT-YGFTGPQCERDY-RTG 184

Query: 437 EDRALCGHGVCYDTYGGFVC 496
               +  + +C     G VC
Sbjct: 185 PCFTVISNQMCQGQLSGIVC 204



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
           C CP G+      + CE D+DECS       GG C + V++Y C C    YT   G RC
Sbjct: 271 CKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  GYT    G +C  D++EC+ A    N   C +   +Y C C   GY     G  C
Sbjct: 2427 CICKTGYTPDITGTSC-VDLNECNQAPKPCNF-ICKNTEGSYQCSCPK-GYILQEDGRSC 2483

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            + +++EC   +  C   +C +T GGF C C P
Sbjct: 2484 K-DLDECATKQHNCQF-LCVNTIGGFTCKCPP 2513



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = +2

Query: 275  YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDR 445
            YTG     D+DEC         G C++ V ++ C+C    +   +   CE +++EC+   
Sbjct: 1760 YTG--LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGP 1816

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
                +  C +T G + C C+P
Sbjct: 1817 VCQRNAECINTAGSYRCDCKP 1837



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NV 424
            C C  G+   + +T   D++EC    AC NG  C + + ++ C C          +  +V
Sbjct: 1874 CLCHTGFKTNDDQTMCLDINECE-RDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDV 1931

Query: 425  NECEEDRA-LCGHGVCYDTYGGFVCAC 502
            +EC      LC +G C +T G F C C
Sbjct: 1932 DECASGNGNLCRNGQCINTVGSFQCQC 1958



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NVNECEEDRALCGHGVCYDTY 481
           D C         GRC+    +  C+C        R E  +V+ECE++   C  G C +  
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQ 508

Query: 482 GGFVCACQPATPGS-TATGCRRV 547
           G + C C+     + T T CR +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDI 531



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 24/83 (28%), Positives = 37/83 (44%)
 Frame = +2

Query: 287  NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            N  T   +C  +     G  C     +  C    +   G +CE +++ECE    +C +G+
Sbjct: 867  NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGL 925

Query: 467  CYDTYGGFVCACQPATPGSTATG 535
            C +T G F C C P+     ATG
Sbjct: 926  CVNTRGSFKCQC-PSGMTLDATG 947



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY----HGTYC 164
            Y C C   YTG+       D C+     C +G +C+ +  G Y C+C  G+     G  C
Sbjct: 1387 YRCLCKEGYTGDGFTCTDLDECSENLNLCGNG-QCL-NAPGGYRCECDMGFVPSADGKAC 1444

Query: 165  EL--EVSLDPLCVAGPCRN 215
            E   E SL  +CV G C N
Sbjct: 1445 EDIDECSLPNICVFGTCHN 1463



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/60 (33%), Positives = 25/60 (41%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C    G P   + C +G RCV   R    C C  G+ G  CE +    P
Sbjct: 134 CLCQKGYIGTHC----GQPVCESGCLNGGRCVAPNR----CACTYGFTGPQCERDYRTGP 185



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +3

Query: 60   DPCASA-ACRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSCS 230
            D C     C+HG +C+    G Y C+CP GY   G  C   V  D   V  PC  NG+C 
Sbjct: 2129 DECKEPDVCKHG-QCINTD-GSYRCECPFGYILAGNEC---VDTDECSVGNPC-GNGTCK 2182

Query: 231  VPPGG 245
               GG
Sbjct: 2183 NVIGG 2187



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
 Frame = +3

Query: 36  NNCEVDAGD---PCASAACRH-GARCVEDGR-GDYSCDCPPGYHGTYCELEVSLDPLCVA 200
           N C   +G     C S + +H   RC+  G   D  C C  GY GT+C       P+C +
Sbjct: 98  NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCG-----QPVCES 152

Query: 201 GPCRNNGSCSVP 236
           G C N G C  P
Sbjct: 153 G-CLNGGRCVAP 163



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 5/86 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYHG---TYCE 167
            ++C C+  + G+  +    D C++    C   A C ++  G Y C C  GY G   T  +
Sbjct: 1346 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC-KNTMGSYRCLCKEGYTGDGFTCTD 1404

Query: 168  LEVSLDPLCVAGPCRNNGSCSVPPGG 245
            L+   + L + G    NG C   PGG
Sbjct: 1405 LDECSENLNLCG----NGQCLNAPGG 1426



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNC-ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP G    +C    +  C+    C+NGG C D      C C   GY G  C   V E
Sbjct: 99  MCTCPSGQIAPSCGSRSIQHCN--IRCMNGGSCSDD----HCLC-QKGYIGTHCGQPVCE 151

Query: 431 --CEEDRALCGHGVCYDTYG 484
             C           C  TYG
Sbjct: 152 SGCLNGGRCVAPNRCACTYG 171



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-SLDPLCVAGPCRNNGSC 227
           D C    C  G  C+ + +G Y+C C  GY  T    E   +D     G   NNG C
Sbjct: 492 DECEKNPCA-GGECINN-QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRC 546



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNN----CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            + C C   +  N+    CE D  +      C+  A C+    G Y CDC PGY  T
Sbjct: 1789 FRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTA-GSYRCDCKPGYRFT 1842



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY--- 161
            + C C   +    TG++CE D  +   +  C+HG + +  G   Y C CP GY   Y   
Sbjct: 2548 FTCECQRGFSLDQTGSSCE-DVDECEGNHRCQHGCQNIIGG---YRCSCPQGYLQHYQWN 2603

Query: 162  -C--ELEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             C  E E     +C    C N  GS  C  P G
Sbjct: 2604 QCVDENECLSAHICGGASCHNTLGSYKCMCPAG 2636



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            ++C C   Y     G  C VD  + C     +      ++  G Y C CPPGY      C
Sbjct: 1954 FQCQCNEGYEVAPDGRTC-VDINE-CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC 2011

Query: 165  E--LEVSLDP-LCVAGPCRN-NGS--CSVPPGGDTYSAPVR-QDTRV 284
            E   E   +P +C  G C N  GS  C  P G    S+  R QD R+
Sbjct: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 2058



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            ++C C + +  ++ E +  D   C  +   C  G +CV    GD+ C C  GY   +  +
Sbjct: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTP-GDFECKCDEGYESGFMMM 1108

Query: 171  -------EVSLDP-LCVAGPCRN-NGS--CSVPPG 242
                   E   DP LC  G C N  GS  C  PPG
Sbjct: 1109 KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 1143



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +++EC+    +C +G C +  G + C C+   TP  T T C
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC 2442



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            Y+C C   Y     G +C+ D  D CA+        CV    G ++C CPPG+  H T C
Sbjct: 2466 YQCSCPKGYILQEDGRSCK-DL-DECATKQHNCQFLCVNT-IGGFTCKCPPGFTQHHTSC 2522

Query: 165  --ELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
                E + D       C + G C   PG  T
Sbjct: 2523 IDNNECTSD----INLCGSKGICQNTPGSFT 2549



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            + C C   Y    +G NC  D  +      C  G  CV    G Y CDCPP +
Sbjct: 1468 FRCECEIGYELDRSGGNC-TDVNECLDPTTCISG-NCVNTP-GSYICDCPPDF 1517



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y+C C A +        C+       A A C +G+   E G   Y C CPPGY
Sbjct: 2629 YKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGSSNTEGG---YLCGCPPGY 2678



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTA----RYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C       Y  N C VD  + C SA    GA C  +  G Y C CP G+
Sbjct: 2588 YRCSCPQGYLQHYQWNQC-VDENE-CLSAHICGGASC-HNTLGSYKCMCPAGF 2637



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGD--PCASAACRHGARCV-EDGRGDYSCDCPPGYHG 155
            CHC   Y+G   +    D   C   A   G   V  +  G + C C PG+ G
Sbjct: 1305 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 27/63 (42%), Positives = 31/63 (49%), Gaps = 9/63 (14%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGY----HGTYC-EL-EVSLDPLCVAGPCRN-NGS--CSV 233
            CR+G  CV D RG Y C C  GY     GT C +L E +  P      C+N  GS  CS 
Sbjct: 2413 CRNG-ECVND-RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSC 2470

Query: 234  PPG 242
            P G
Sbjct: 2471 PKG 2473



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            N CE+ A        C +G RCV +  G Y C C PGYH T
Sbjct: 1157 NECELSAH------LCPNG-RCV-NLIGKYQCACNPGYHST 1189



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C   YT    G +C VD  + C  A       C ++  G Y C CP GY
Sbjct: 2425 YHCICKTGYTPDITGTSC-VDLNE-CNQAPKPCNFIC-KNTEGSYQCSCPKGY 2474


>BC008761-1|AAH08761.2|  743|Homo sapiens LTBP3 protein protein.
          Length = 743

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  GY       +CE D+DEC   AAC+ GG C++   +Y C C   G+    G +C+
Sbjct: 296 CQCLSGYHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQ-GHRLVGGRKCQ 352

Query: 416 TNVNECEEDRALC-GHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
            +++EC +D +LC  HG C +  G +VC C    TP     GC  V Q
Sbjct: 353 -DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 399



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 12/111 (10%)
 Frame = +2

Query: 257 CTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGAR- 409
           C C  GY       GR+C  D++EC+    C +GG C++   +Y C+C   GY    +R 
Sbjct: 128 CHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNC-YPGYRLKASRP 185

Query: 410 --CETNVNECEEDRALCGHGVCYDTYGGFVC-ACQPATPGSTATGCRRVRQ 553
             CE +++EC  D + C  G C +  G F C ACQP         CR V +
Sbjct: 186 PVCE-DIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 234



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 39/106 (36%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRN--------CETDVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATG 394
           H LC    GYT  N           D+DEC   G+  C  G +CV+    Y C C     
Sbjct: 455 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFY 513

Query: 395 YTGARCE-TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA 529
           Y G   E  +V+EC  D + C +GVC +T GG+ CAC P    S A
Sbjct: 514 YDGNLLECVDVDECL-DESNCRNGVCENTRGGYRCACTPPAEYSPA 558



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYT--GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVN 427
           C PGY   G     DV+EC+  + C + G C +   ++ C C A GY  A   R   +V+
Sbjct: 217 CQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTC-AQGYAPAPDGRSCLDVD 274

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           ECE    +C +G+C +T G F C C
Sbjct: 275 ECEAGD-VCDNGICSNTPGSFQCQC 298



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDRALCGHGV 466
           T+ DEC         G CV    +Y+C C   GY      R   +VNECE +    G G+
Sbjct: 60  TETDECRLNQNICGHGECVPGPPDYSCHCNP-GYRSHPQHRYCVDVNECEAEPCGPGRGI 118

Query: 467 CYDTYGGFVCAC 502
           C +T G + C C
Sbjct: 119 CMNTGGSYNCHC 130



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3   YECHCTARYT------GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           Y CHC   Y       G +C VD  +      C  G  C+ +  G Y C+C PGY     
Sbjct: 126 YNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGY----- 178

Query: 165 ELEVSLDPLCV-AGPCRNNGSC 227
            L+ S  P+C     CR+  SC
Sbjct: 179 RLKASRPPVCEDIDECRDPSSC 200



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +2

Query: 293 ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEE--DRAL- 451
           E D DEC     C++G RCV       C+C   G+    + ARC  +++EC E   R L 
Sbjct: 655 EEDSDECR----CVSG-RCVPRPGGAVCECPG-GFQLDASRARC-VDIDECRELNQRGLL 707

Query: 452 CGHGVCYDTYGGFVCACQ 505
           C    C +T G F C C+
Sbjct: 708 CKSERCVNTSGSFRCVCK 725



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 17/97 (17%)
 Frame = +3

Query: 3   YECHCTARYT----GNNC----EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH-- 152
           + C C   Y     G +C    E +AGD C +  C +         G + C C  GYH  
Sbjct: 253 FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTP-------GSFQCQCLSGYHLS 305

Query: 153 --GTYCE--LEVSLDPLCVAGPCRN-NGS--CSVPPG 242
              ++CE   E      C+ G C N NGS  C  P G
Sbjct: 306 RDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQG 342



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 3   YECHCTAR--YTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPP 143
           YEC+C     Y GN  E    D C   + CR+G  C E+ RG Y C C P
Sbjct: 504 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGV-C-ENTRGGYRCACTP 551



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 11/31 (35%), Positives = 16/31 (51%)
 Frame = +2

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           T  +EC  ++ +CGHG C      + C C P
Sbjct: 60  TETDECRLNQNICGHGECVPGPPDYSCHCNP 90



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD-PLCVAGPCRNNGSCSVPPGG 245
           C HG  CV  G  DYSC C PGY  ++ +    +D   C A PC       +  GG
Sbjct: 72  CGHG-ECVP-GPPDYSCHCNPGYR-SHPQHRYCVDVNECEAEPCGPGRGICMNTGG 124



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCE---VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH---GTYC 164
           Y CHC   Y  +      VD  + C +  C  G     +  G Y+C C  GY    G   
Sbjct: 84  YSCHCNPGYRSHPQHRYCVDVNE-CEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 142

Query: 165 ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              V L+       C + G C   PG
Sbjct: 143 RSCVDLNECAKPHLCGDGGFCINFPG 168


>AL117551-1|CAB55988.1|  511|Homo sapiens hypothetical protein
           protein.
          Length = 511

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  GY       +CE D+DEC   AAC+ GG C++   +Y C C   G+    G +C+
Sbjct: 17  CQCLSGYHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQ-GHRLVGGRKCQ 73

Query: 416 TNVNECEEDRALC-GHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
            +++EC +D +LC  HG C +  G +VC C    TP     GC  V Q
Sbjct: 74  -DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 120



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 39/106 (36%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRN--------CETDVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATG 394
           H LC    GYT  N           D+DEC   G+  C  G +CV+    Y C C     
Sbjct: 176 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFY 234

Query: 395 YTGARCE-TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA 529
           Y G   E  +V+EC  D + C +GVC +T GG+ CAC P    S A
Sbjct: 235 YDGNLLECVDVDECL-DESNCRNGVCENTRGGYRCACTPPAEYSPA 279



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 38/106 (35%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
 Frame = +2

Query: 257 CTCPPG--YTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATG-YTGAR--C-- 412
           C C  G  Y G   E  DVDEC   + C NG  C +    Y C CT    Y+ A+  C  
Sbjct: 227 CYCKQGFYYDGNLLECVDVDECLDESNCRNGV-CENTRGGYRCACTPPAEYSPAQRQCLS 285

Query: 413 --ETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCR 541
             E +V+EC+ D A C  G C +  G + C C+P   PG +   C+
Sbjct: 286 PEEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQ 330



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +2

Query: 293 ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEE--DRAL- 451
           E D DEC     C++G RCV       C+C   G+    + ARC  +++EC E   R L 
Sbjct: 423 EEDSDECR----CVSG-RCVPRPGGAVCECPG-GFQLDASRARC-VDIDECRELNQRGLL 475

Query: 452 CGHGVCYDTYGGFVCACQ 505
           C    C +T G F C C+
Sbjct: 476 CKSERCVNTSGSFRCVCK 493



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 3   YECHCTAR--YTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPP 143
           YEC+C     Y GN  E    D C   + CR+G  C E+ RG Y C C P
Sbjct: 225 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGV-C-ENTRGGYRCACTP 272



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 9/51 (17%)
 Frame = +3

Query: 117 GDYSCDCPPGYH----GTYCE--LEVSLDPLCVAGPCRN-NGS--CSVPPG 242
           G + C C  GYH     ++CE   E      C+ G C N NGS  C  P G
Sbjct: 13  GSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQG 63


>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
          Length = 1382

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY       +CE D+DEC   AAC+ GG C++   +Y C C   G+    G +C+
Sbjct: 888  CQCLSGYHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQ-GHRLVGGRKCQ 944

Query: 416  TNVNECEEDRALC-GHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
             +++EC +D +LC  HG C +  G +VC C    TP     GC  V Q
Sbjct: 945  -DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 991



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 12/111 (10%)
 Frame = +2

Query: 257  CTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGAR- 409
            C C  GY       GR+C  D++EC+    C +GG C++   +Y C+C   GY    +R 
Sbjct: 720  CHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNC-YPGYRLKASRP 777

Query: 410  --CETNVNECEEDRALCGHGVCYDTYGGFVC-ACQPATPGSTATGCRRVRQ 553
              CE +++EC  D + C  G C +  G F C ACQP         CR V +
Sbjct: 778  PVCE-DIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 826



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 39/106 (36%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRN--------CETDVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATG 394
            H LC    GYT  N           D+DEC   G+  C  G +CV+    Y C C     
Sbjct: 1047 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFY 1105

Query: 395  YTGARCE-TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA 529
            Y G   E  +V+EC  D + C +GVC +T GG+ CAC P    S A
Sbjct: 1106 YDGNLLECVDVDECL-DESNCRNGVCENTRGGYRCACTPPAEYSPA 1150



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 38/106 (35%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
 Frame = +2

Query: 257  CTCPPG--YTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATG-YTGAR--C-- 412
            C C  G  Y G   E  DVDEC   + C NG  C +    Y C CT    Y+ A+  C  
Sbjct: 1098 CYCKQGFYYDGNLLECVDVDECLDESNCRNGV-CENTRGGYRCACTPPAEYSPAQRQCLS 1156

Query: 413  --ETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCR 541
              E +V+EC+ D A C  G C +  G + C C+P   PG +   C+
Sbjct: 1157 PEEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQ 1201



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263  CPPGYT--GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVN 427
            C PGY   G     DV+EC+  + C + G C +   ++ C C A GY  A   R   +V+
Sbjct: 809  CQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTC-AQGYAPAPDGRSCLDVD 866

Query: 428  ECEEDRALCGHGVCYDTYGGFVCAC 502
            ECE    +C +G+C +T G F C C
Sbjct: 867  ECEAGD-VCDNGICSNTPGSFQCQC 890



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDRALCGHGV 466
           T+ DEC         G CV    +Y+C C   GY      R   +VNECE +    G G+
Sbjct: 652 TETDECRLNQNICGHGECVPGPPDYSCHCNP-GYRSHPQHRYCVDVNECEAEPCGPGRGI 710

Query: 467 CYDTYGGFVCAC 502
           C +T G + C C
Sbjct: 711 CMNTGGSYNCHC 722



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3   YECHCTARYT------GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           Y CHC   Y       G +C VD  +      C  G  C+ +  G Y C+C PGY     
Sbjct: 718 YNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGY----- 770

Query: 165 ELEVSLDPLCV-AGPCRNNGSC 227
            L+ S  P+C     CR+  SC
Sbjct: 771 RLKASRPPVCEDIDECRDPSSC 792



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEE--DRAL- 451
            E D DEC     C++G RCV       C+C   G+    + ARC  +++EC E   R L 
Sbjct: 1294 EEDSDECR----CVSG-RCVPRPGGAVCECPG-GFQLDASRARC-VDIDECRELNQRGLL 1346

Query: 452  CGHGVCYDTYGGFVCACQ 505
            C    C +T G F C C+
Sbjct: 1347 CKSERCVNTSGSFRCVCK 1364



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 17/97 (17%)
 Frame = +3

Query: 3    YECHCTARYT----GNNC----EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH-- 152
            + C C   Y     G +C    E +AGD C +  C +         G + C C  GYH  
Sbjct: 845  FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTP-------GSFQCQCLSGYHLS 897

Query: 153  --GTYCE--LEVSLDPLCVAGPCRN-NGS--CSVPPG 242
               ++CE   E      C+ G C N NGS  C  P G
Sbjct: 898  RDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQG 934



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 8/51 (15%)
 Frame = +3

Query: 114 RGDYSCDCPPGY---HGTYCE--LEVSLDPLCVAGPCRNN-GS--CSVPPG 242
           RG+   DCP GY   + T+C+   E ++  +C  G C NN GS  C  PPG
Sbjct: 413 RGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPG 463



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
           P R  +   CP GY   N   C+ D++EC+    C +G  C++   +Y C C      G 
Sbjct: 411 PVRGEVGADCPQGYKRLNSTHCQ-DINECAMPGVCRHGD-CLNNPGSYRCVCPPGHSLGP 468

Query: 407 RCETNVNECEEDRALC 454
                + +  E+++LC
Sbjct: 469 SRTQCIADKPEEKSLC 484



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 3    YECHCTAR--YTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPP 143
            YEC+C     Y GN  E    D C   + CR+G  C E+ RG Y C C P
Sbjct: 1096 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGV-C-ENTRGGYRCACTP 1143



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = +3

Query: 24  RYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           R    +C+ D  +      CRHG  C+ +  G Y C CPPG+
Sbjct: 426 RLNSTHCQ-DINECAMPGVCRHGD-CLNNP-GSYRCVCPPGH 464



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 11/31 (35%), Positives = 16/31 (51%)
 Frame = +2

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           T  +EC  ++ +CGHG C      + C C P
Sbjct: 652 TETDECRLNQNICGHGECVPGPPDYSCHCNP 682



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD-PLCVAGPCRNNGSCSVPPGG 245
           C HG  CV  G  DYSC C PGY  ++ +    +D   C A PC       +  GG
Sbjct: 664 CGHG-ECVP-GPPDYSCHCNPGYR-SHPQHRYCVDVNECEAEPCGPGRGICMNTGG 716



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCE---VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH---GTYC 164
           Y CHC   Y  +      VD  + C +  C  G     +  G Y+C C  GY    G   
Sbjct: 676 YSCHCNPGYRSHPQHRYCVDVNE-CEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 734

Query: 165 ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              V L+       C + G C   PG
Sbjct: 735 RSCVDLNECAKPHLCGDGGFCINFPG 760



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC     +C HG C +  G + C C P  + G + T C
Sbjct: 434 DINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 473


>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
            factor beta binding protein 3 protein.
          Length = 1256

 Score = 70.1 bits (164), Expect = 6e-12
 Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY       +CE D+DEC   AAC+ GG C++   +Y C C   G+    G +C+
Sbjct: 809  CQCLSGYHLSRDRSHCE-DIDECDFPAACI-GGDCINTNGSYRCLCPQ-GHRLVGGRKCQ 865

Query: 416  TNVNECEEDRALC-GHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
             +++EC +D +LC  HG C +  G +VC C    TP     GC  V Q
Sbjct: 866  -DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQ 912



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 12/111 (10%)
 Frame = +2

Query: 257 CTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGAR- 409
           C C  GY       GR+C  D++EC+    C +GG C++   +Y C+C   GY    +R 
Sbjct: 641 CHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCINFPGHYKCNC-YPGYRLKASRP 698

Query: 410 --CETNVNECEEDRALCGHGVCYDTYGGFVC-ACQPATPGSTATGCRRVRQ 553
             CE +++EC  D + C  G C +  G F C ACQP         CR V +
Sbjct: 699 PVCE-DIDEC-RDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNE 747



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 39/106 (36%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRN--------CETDVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATG 394
            H LC    GYT  N           D+DEC   G+  C  G +CV+    Y C C     
Sbjct: 968  HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFY 1026

Query: 395  YTGARCE-TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA 529
            Y G   E  +V+EC  D + C +GVC +T GG+ CAC P    S A
Sbjct: 1027 YDGNLLECVDVDECL-DESNCRNGVCENTRGGYRCACTPPAEYSPA 1071



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYT--GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVN 427
           C PGY   G     DV+EC+  + C + G C +   ++ C C A GY  A   R   +V+
Sbjct: 730 CQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTC-AQGYAPAPDGRSCLDVD 787

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           ECE    +C +G+C +T G F C C
Sbjct: 788 ECEAGD-VCDNGICSNTPGSFQCQC 811



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDRALCGHGV 466
           T+ DEC         G CV    +Y+C C   GY      R   +VNECE +    G G+
Sbjct: 573 TETDECRLNQNICGHGECVPGPPDYSCHCNP-GYRSHPQHRYCVDVNECEAEPCGPGRGI 631

Query: 467 CYDTYGGFVCAC 502
           C +T G + C C
Sbjct: 632 CMNTGGSYNCHC 643



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
 Frame = +3

Query: 3   YECHCTARYT------GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           Y CHC   Y       G +C VD  +      C  G  C+ +  G Y C+C PGY     
Sbjct: 639 YNCHCNRGYRLHVGAGGRSC-VDLNECAKPHLCGDGGFCI-NFPGHYKCNCYPGY----- 691

Query: 165 ELEVSLDPLCV-AGPCRNNGSC 227
            L+ S  P+C     CR+  SC
Sbjct: 692 RLKASRPPVCEDIDECRDPSSC 713



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEE--DRAL- 451
            E D DEC     C++G RCV       C+C   G+    + ARC  +++EC E   R L 
Sbjct: 1168 EEDSDECR----CVSG-RCVPRPGGAVCECPG-GFQLDASRARC-VDIDECRELNQRGLL 1220

Query: 452  CGHGVCYDTYGGFVCACQ 505
            C    C +T G F C C+
Sbjct: 1221 CKSERCVNTSGSFRCVCK 1238



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 17/97 (17%)
 Frame = +3

Query: 3    YECHCTARYT----GNNC----EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH-- 152
            + C C   Y     G +C    E +AGD C +  C +         G + C C  GYH  
Sbjct: 766  FRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTP-------GSFQCQCLSGYHLS 818

Query: 153  --GTYCE--LEVSLDPLCVAGPCRN-NGS--CSVPPG 242
               ++CE   E      C+ G C N NGS  C  P G
Sbjct: 819  RDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQG 855



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 8/51 (15%)
 Frame = +3

Query: 114 RGDYSCDCPPGY---HGTYCE--LEVSLDPLCVAGPCRNN-GS--CSVPPG 242
           RG+   DCP GY   + T+C+   E ++  +C  G C NN GS  C  PPG
Sbjct: 334 RGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCPPG 384



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA 406
           P R  +   CP GY   N   C+ D++EC+    C +G  C++   +Y C C      G 
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQ-DINECAMPGVCRHGD-CLNNPGSYRCVCPPGHSLGP 389

Query: 407 RCETNVNECEEDRALC 454
                + +  E+++LC
Sbjct: 390 SRTQCIADKPEEKSLC 405



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +3

Query: 3    YECHCTAR--YTGNNCEVDAGDPCASAA-CRHGARCVEDGRGDYSCDCPP 143
            YEC+C     Y GN  E    D C   + CR+G  C E+ RG Y C C P
Sbjct: 1017 YECYCKQGFYYDGNLLECVDVDECLDESNCRNGV-C-ENTRGGYRCACTP 1064



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = +3

Query: 24  RYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           R    +C+ D  +      CRHG  C+ +  G Y C CPPG+
Sbjct: 347 RLNSTHCQ-DINECAMPGVCRHGD-CLNNP-GSYRCVCPPGH 385



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 11/31 (35%), Positives = 16/31 (51%)
 Frame = +2

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           T  +EC  ++ +CGHG C      + C C P
Sbjct: 573 TETDECRLNQNICGHGECVPGPPDYSCHCNP 603



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD-PLCVAGPCRNNGSCSVPPGG 245
           C HG  CV  G  DYSC C PGY  ++ +    +D   C A PC       +  GG
Sbjct: 585 CGHG-ECVP-GPPDYSCHCNPGYR-SHPQHRYCVDVNECEAEPCGPGRGICMNTGG 637



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 6/86 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCE---VDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH---GTYC 164
           Y CHC   Y  +      VD  + C +  C  G     +  G Y+C C  GY    G   
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNE-CEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 655

Query: 165 ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              V L+       C + G C   PG
Sbjct: 656 RSCVDLNECAKPHLCGDGGFCINFPG 681



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC     +C HG C +  G + C C P  + G + T C
Sbjct: 355 DINECAMP-GVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394


>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
           factor-cobalamin receptor) protein.
          Length = 3623

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGR----NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LCTC PGYTG     N    +     +  CLNG +C+D V+ Y C C + G+TG  C  N
Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDS-GWTGVNCTEN 432

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  L G G C D    F C C
Sbjct: 433 INECLSNPCLNG-GTCVDGVDSFSCEC 458



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC---SGAA-ACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C CPP + G  C  DV+EC   SG   +C NGG CV+ + +Y+C C    Y G +C +  
Sbjct: 156 CICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETY-GPQCASKY 214

Query: 425 NECEEDR-ALCGHGVCYD 475
           ++CE    A C HG+C D
Sbjct: 215 DDCEGGSVARCVHGICED 232



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG NC  +++EC  +  CLNGG CVD V++++C+CT   +TGA C+     C 
Sbjct: 418 CKCDSGWTGVNCTENINECL-SNPCLNGGTCVDGVDSFSCECTRL-WTGALCQVPQQVCG 475

Query: 437 E 439
           E
Sbjct: 476 E 476



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 275 YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRAL- 451
           + G     D   CS +  C NGG C++  +++ C C    + G  C  +VNECE      
Sbjct: 124 FQGLQQTVDKKVCS-SNPCQNGGTCLNLHDSFFCICPPQ-WKGPLCSADVNECEIYSGTP 181

Query: 452 --CGHG-VCYDTYGGFVCACQPATPG 520
             C +G  C +T G + C C P T G
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYG 207



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +3

Query: 9   CHCTARYTGN----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   YTGN    N  V   + C S  C +G +C++   G Y C C  G+ G  C   +
Sbjct: 376 CTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSG-YFCKCDSGWTGVNCTENI 433

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           +    C++ PC N G+C    G D++S
Sbjct: 434 NE---CLSNPCLNGGTC--VDGVDSFS 455



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           Y C C + +TG NC  +  + C S  C +G  CV DG   +SC+C   + G  C++
Sbjct: 416 YFCKCDSGWTGVNCTENINE-CLSNPCLNGGTCV-DGVDSFSCECTRLWTGALCQV 469



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGA--AACLNGGRCVDAVNN------YTCDCTATGY---TG 403
           C CPP   G  C +  D+C G   A C++G  C D +        Y+C C A        
Sbjct: 199 CHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNS 257

Query: 404 ARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQP 508
             C  + +EC      C   V C++T G F C   P
Sbjct: 258 PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 293



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           N CE+ +G P +   C++G  CV    G YSC CPP  +G  C
Sbjct: 172 NECEIYSGTPLS---CQNGGTCVNT-MGSYSCHCPPETYGPQC 210



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
 Frame = +2

Query: 263 CPPGYTG--RNCETDVDECSGA-AACLNGGRCVDAVNNYT-CDC----TATGYTGARCET 418
           CPPGY G  R C T  D CS +   C     C   + +   C C    T  GY    C  
Sbjct: 336 CPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 394

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             N C      C +G C DT  G+ C C     G   T
Sbjct: 395 LSNICLSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCT 430



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP--CRNNGSC 227
           C+S  C++G  C+ +    + C CPP + G  C  +V+   +    P  C+N G+C
Sbjct: 136 CSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190


>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
           factor-cobalamin receptor) protein.
          Length = 3623

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGR----NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LCTC PGYTG     N    +     +  CLNG +C+D V+ Y C C + G+TG  C  N
Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDS-GWTGVNCTEN 432

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  L G G C D    F C C
Sbjct: 433 INECLSNPCLNG-GTCVDGVDSFSCEC 458



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC---SGAA-ACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C CPP + G  C  DV+EC   SG   +C NGG CV+ + +Y+C C    Y G +C +  
Sbjct: 156 CICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETY-GPQCASKY 214

Query: 425 NECEEDR-ALCGHGVCYD 475
           ++CE    A C HG+C D
Sbjct: 215 DDCEGGSVARCVHGICED 232



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG NC  +++EC  +  CLNGG CVD V++++C+CT   +TGA C+     C 
Sbjct: 418 CKCDSGWTGVNCTENINECL-SNPCLNGGTCVDGVDSFSCECTRL-WTGALCQVPQQVCG 475

Query: 437 E 439
           E
Sbjct: 476 E 476



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 275 YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRAL- 451
           + G     D   CS +  C NGG C++  +++ C C    + G  C  +VNECE      
Sbjct: 124 FQGLQQTVDKKVCS-SNPCQNGGTCLNLHDSFFCICPPQ-WKGPLCSADVNECEIYSGTP 181

Query: 452 --CGHG-VCYDTYGGFVCACQPATPG 520
             C +G  C +T G + C C P T G
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYG 207



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +3

Query: 9   CHCTARYTGN----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   YTGN    N  V   + C S  C +G +C++   G Y C C  G+ G  C   +
Sbjct: 376 CTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSG-YFCKCDSGWTGVNCTENI 433

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           +    C++ PC N G+C    G D++S
Sbjct: 434 NE---CLSNPCLNGGTC--VDGVDSFS 455



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           Y C C + +TG NC  +  + C S  C +G  CV DG   +SC+C   + G  C++
Sbjct: 416 YFCKCDSGWTGVNCTENINE-CLSNPCLNGGTCV-DGVDSFSCECTRLWTGALCQV 469



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGA--AACLNGGRCVDAVNN------YTCDCTATGY---TG 403
           C CPP   G  C +  D+C G   A C++G  C D +        Y+C C A        
Sbjct: 199 CHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNS 257

Query: 404 ARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQP 508
             C  + +EC      C   V C++T G F C   P
Sbjct: 258 PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 293



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           N CE+ +G P +   C++G  CV    G YSC CPP  +G  C
Sbjct: 172 NECEIYSGTPLS---CQNGGTCVNT-MGSYSCHCPPETYGPQC 210



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
 Frame = +2

Query: 263 CPPGYTG--RNCETDVDECSGA-AACLNGGRCVDAVNNYT-CDC----TATGYTGARCET 418
           CPPGY G  R C T  D CS +   C     C   + +   C C    T  GY    C  
Sbjct: 336 CPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 394

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             N C      C +G C DT  G+ C C     G   T
Sbjct: 395 LSNICLSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCT 430



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP--CRNNGSC 227
           C+S  C++G  C+ +    + C CPP + G  C  +V+   +    P  C+N G+C
Sbjct: 136 CSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190


>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
           factor-cobalamin receptor) protein.
          Length = 3623

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGR----NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LCTC PGYTG     N    +     +  CLNG +C+D V+ Y C C + G+TG  C  N
Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDS-GWTGVNCTEN 432

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  L G G C D    F C C
Sbjct: 433 INECLSNPCLNG-GTCVDGVDSFSCEC 458



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC---SGAA-ACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C CPP + G  C  DV+EC   SG   +C NGG CV+ + +Y+C C    Y G +C +  
Sbjct: 156 CICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETY-GPQCASKY 214

Query: 425 NECEEDR-ALCGHGVCYD 475
           ++CE    A C HG+C D
Sbjct: 215 DDCEGGSVARCVHGICED 232



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG NC  +++EC  +  CLNGG CVD V++++C+CT   +TGA C+     C 
Sbjct: 418 CKCDSGWTGVNCTENINECL-SNPCLNGGTCVDGVDSFSCECTRL-WTGALCQVPQQVCG 475

Query: 437 E 439
           E
Sbjct: 476 E 476



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 275 YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRAL- 451
           + G     D   CS +  C NGG C++  +++ C C    + G  C  +VNECE      
Sbjct: 124 FQGLQQTVDKKVCS-SNPCQNGGTCLNLHDSFFCICPPQ-WKGPLCSADVNECEIYSGTP 181

Query: 452 --CGHG-VCYDTYGGFVCACQPATPG 520
             C +G  C +T G + C C P T G
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYG 207



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +3

Query: 9   CHCTARYTGN----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   YTGN    N  V   + C S  C +G +C++   G Y C C  G+ G  C   +
Sbjct: 376 CTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSG-YFCKCDSGWTGVNCTENI 433

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           +    C++ PC N G+C    G D++S
Sbjct: 434 NE---CLSNPCLNGGTC--VDGVDSFS 455



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           Y C C + +TG NC  +  + C S  C +G  CV DG   +SC+C   + G  C++
Sbjct: 416 YFCKCDSGWTGVNCTENINE-CLSNPCLNGGTCV-DGVDSFSCECTRLWTGALCQV 469



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGA--AACLNGGRCVDAVNN------YTCDCTATGY---TG 403
           C CPP   G  C +  D+C G   A C++G  C D +        Y+C C A        
Sbjct: 199 CHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMFSPNS 257

Query: 404 ARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQP 508
             C  + +EC      C   V C++T G F C   P
Sbjct: 258 PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 293



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           N CE+ +G P +   C++G  CV    G YSC CPP  +G  C
Sbjct: 172 NECEIYSGTPLS---CQNGGTCVNT-MGSYSCHCPPETYGPQC 210



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
 Frame = +2

Query: 263 CPPGYTG--RNCETDVDECSGA-AACLNGGRCVDAVNNYT-CDC----TATGYTGARCET 418
           CPPGY G  R C T  D CS +   C     C   + +   C C    T  GY    C  
Sbjct: 336 CPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 394

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             N C      C +G C DT  G+ C C     G   T
Sbjct: 395 LSNICLSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCT 430



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP--CRNNGSC 227
           C+S  C++G  C+ +    + C CPP + G  C  +V+   +    P  C+N G+C
Sbjct: 136 CSSNPCQNGGTCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190


>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
           B12 receptor protein.
          Length = 3494

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGR----NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LCTC PGYTG     N    +     +  CLNG +C+D V+ Y C C + G+TG  C  N
Sbjct: 246 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDS-GWTGVNCTEN 303

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  L G G C D    F C C
Sbjct: 304 INECLSNPCLNG-GTCVDGVDSFSCEC 329



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC---SGAA-ACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C CPP + G  C  DV+EC   SG   +C NGG CV+ + +Y+C C    Y G +C +  
Sbjct: 27  CICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETY-GPQCASKY 85

Query: 425 NECEEDR-ALCGHGVCYD 475
           ++CE    A C HG+C D
Sbjct: 86  DDCEGGSVARCVHGICED 103



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG NC  +++EC  +  CLNGG CVD V++++C+CT   +TGA C+     C 
Sbjct: 289 CKCDSGWTGVNCTENINECL-SNPCLNGGTCVDGVDSFSCECTRL-WTGALCQVPQQVCG 346

Query: 437 E 439
           E
Sbjct: 347 E 347



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRAL---CGHG-V 466
           D   CS +  C NGG C++  +++ C C    + G  C  +VNECE        C +G  
Sbjct: 3   DKKVCS-SNPCQNGGNCLNLHDSFFCICPPQ-WKGPLCSADVNECEIYSGTPLSCQNGGT 60

Query: 467 CYDTYGGFVCACQPATPG 520
           C +T G + C C P T G
Sbjct: 61  CVNTMGSYSCHCPPETYG 78



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +3

Query: 9   CHCTARYTGN----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   YTGN    N  V   + C S  C +G +C++   G Y C C  G+ G  C   +
Sbjct: 247 CTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSG-YFCKCDSGWTGVNCTENI 304

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           +    C++ PC N G+C    G D++S
Sbjct: 305 NE---CLSNPCLNGGTC--VDGVDSFS 326



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           Y C C + +TG NC  +  + C S  C +G  CV DG   +SC+C   + G  C++
Sbjct: 287 YFCKCDSGWTGVNCTENINE-CLSNPCLNGGTCV-DGVDSFSCECTRLWTGALCQV 340



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 12/96 (12%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGA--AACLNGGRCVDAVNN------YTCDCTA---TGYTG 403
           C CPP   G  C +  D+C G   A C++G  C D +        Y+C C A   +    
Sbjct: 70  CHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMSSPNS 128

Query: 404 ARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQP 508
             C  + +EC      C   V C++T G F C   P
Sbjct: 129 PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 164



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           N CE+ +G P +   C++G  CV    G YSC CPP  +G  C
Sbjct: 43  NECEIYSGTPLS---CQNGGTCVNT-MGSYSCHCPPETYGPQC 81



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
 Frame = +2

Query: 263 CPPGYTG--RNCETDVDECSGA-AACLNGGRCVDAVNNYT-CDC----TATGYTGARCET 418
           CPPGY G  R C T  D CS +   C     C   + +   C C    T  GY    C  
Sbjct: 207 CPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 265

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             N C      C +G C DT  G+ C C     G   T
Sbjct: 266 LSNICLSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCT 301



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP--CRNNGSC 227
           C+S  C++G  C+ +    + C CPP + G  C  +V+   +    P  C+N G+C
Sbjct: 7   CSSNPCQNGGNCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 61


>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
           receptor precursor protein.
          Length = 3623

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGR----NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LCTC PGYTG     N    +     +  CLNG +C+D V+ Y C C + G+TG  C  N
Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFCKCDS-GWTGVNCTEN 432

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  L G G C D    F C C
Sbjct: 433 INECLSNPCLNG-GTCVDGVDSFSCEC 458



 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDEC---SGAA-ACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
           C CPP + G  C  DV+EC   SG   +C NGG CV+ + +Y+C C    Y G +C +  
Sbjct: 156 CICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETY-GPQCASKY 214

Query: 425 NECEEDR-ALCGHGVCYD 475
           ++CE    A C HG+C D
Sbjct: 215 DDCEGGSVARCVHGICED 232



 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 27/61 (44%), Positives = 39/61 (63%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+TG NC  +++EC  +  CLNGG CVD V++++C+CT   +TGA C+     C 
Sbjct: 418 CKCDSGWTGVNCTENINECL-SNPCLNGGTCVDGVDSFSCECTRL-WTGALCQVPQQVCG 475

Query: 437 E 439
           E
Sbjct: 476 E 476



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
 Frame = +2

Query: 275 YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRAL- 451
           + G     D   CS +  C NGG C++  +++ C C    + G  C  +VNECE      
Sbjct: 124 FQGLQQTVDKKVCS-SNPCQNGGNCLNLHDSFFCICPPQ-WKGPLCSADVNECEIYSGTP 181

Query: 452 --CGHG-VCYDTYGGFVCACQPATPG 520
             C +G  C +T G + C C P T G
Sbjct: 182 LSCQNGGTCVNTMGSYSCHCPPETYG 207



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
 Frame = +3

Query: 9   CHCTARYTGN----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           C C   YTGN    N  V   + C S  C +G +C++   G Y C C  G+ G  C   +
Sbjct: 376 CTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSG-YFCKCDSGWTGVNCTENI 433

Query: 177 SLDPLCVAGPCRNNGSCSVPPGGDTYS 257
           +    C++ PC N G+C    G D++S
Sbjct: 434 NE---CLSNPCLNGGTC--VDGVDSFS 455



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           Y C C + +TG NC  +  + C S  C +G  CV DG   +SC+C   + G  C++
Sbjct: 416 YFCKCDSGWTGVNCTENINE-CLSNPCLNGGTCV-DGVDSFSCECTRLWTGALCQV 469



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 12/96 (12%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGA--AACLNGGRCVDAVNN------YTCDCTA---TGYTG 403
           C CPP   G  C +  D+C G   A C++G  C D +        Y+C C A   +    
Sbjct: 199 CHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYSCVCDAGWMSSPNS 257

Query: 404 ARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQP 508
             C  + +EC      C   V C++T G F C   P
Sbjct: 258 PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 293



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 18/43 (41%), Positives = 24/43 (55%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC 164
           N CE+ +G P +   C++G  CV    G YSC CPP  +G  C
Sbjct: 172 NECEIYSGTPLS---CQNGGTCVNT-MGSYSCHCPPETYGPQC 210



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 8/98 (8%)
 Frame = +2

Query: 263 CPPGYTG--RNCETDVDECSGA-AACLNGGRCVDAVNNYT-CDC----TATGYTGARCET 418
           CPPGY G  R C T  D CS +   C     C   + +   C C    T  GY    C  
Sbjct: 336 CPPGYQGDGRVC-TLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 394

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             N C      C +G C DT  G+ C C     G   T
Sbjct: 395 LSNICLSHP--CLNGQCIDTVSGYFCKCDSGWTGVNCT 430



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP--CRNNGSC 227
           C+S  C++G  C+ +    + C CPP + G  C  +V+   +    P  C+N G+C
Sbjct: 136 CSSNPCQNGGNCL-NLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC 190


>AB208840-1|BAD92077.1|  830|Homo sapiens fibrillin 1 variant
           protein.
          Length = 830

 Score = 69.7 bits (163), Expect = 8e-12
 Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCE 415
           C CP G+   +    CE D+DEC     C     C++   +Y CDC   GY   +  +C 
Sbjct: 226 CECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTAGSYRCDCKP-GYRFTSTGQCN 283

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              NEC+E   +C HG C DT G F C C
Sbjct: 284 DR-NECQEIPNICSHGQCIDTVGSFYCLC 311



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEEDRALCGHGVC 469
           D+DEC        GG+C++   ++ C C  TGY      R   +VNECE    +CG G C
Sbjct: 41  DIDECQELPGLCQGGKCINTFGSFQCRCP-TGYYLNEDTRVCDDVNECETP-GICGPGTC 98

Query: 470 YDTYGGFVCACQP 508
           Y+T G + C C P
Sbjct: 99  YNTVGNYTCICPP 111



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
           C C PGY  T      D +EC       + G+C+D V ++ C C  TG+     +T   +
Sbjct: 268 CDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCH-TGFKTNDDQTMCLD 326

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NECE D   CG+G C +T G F C C
Sbjct: 327 INECERDA--CGNGTCRNTIGSFNCRC 351



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
           C CP GY   G  C  D DECS    C NG  C + +  + C C      G    CE ++
Sbjct: 586 CECPFGYILAGNEC-VDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCE-DI 642

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           NEC ++  LC    C +TYG + C C
Sbjct: 643 NECAQNPLLCAFR-CVNTYGSYECKC 667



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
           C C  GY     GR C  D++EC         G C +   +Y C C   GY+    +CE 
Sbjct: 391 CQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPP-GYSLQNEKCE- 447

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRVR 550
           +++EC E+  +C  G C +T G F C C +  +  S+   C+ +R
Sbjct: 448 DIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLR 492



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGARCETNVNECEEDRALCGHGVCY 472
           D+DEC     C +G +C++   +Y C+C   GY   G  C  + +EC      CG+G C 
Sbjct: 562 DMDECKEPDVCKHG-QCINTDGSYRCECPF-GYILAGNEC-VDTDECSVGNP-CGNGTCK 617

Query: 473 DTYGGFVCACQPA-TPGSTATGCRRVRQ 553
           +  GGF C C+    PG   T C  + +
Sbjct: 618 NVIGGFECTCEEGFEPGPMMT-CEDINE 644



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
 Frame = +2

Query: 257 CTCPPGYTGRN----CETDVDECS-GAAACLNGG-RCVDAVNNYTCDCTATGYT----GA 406
           C CP GY  R     C+ D DEC  G   C      C + +  Y C C   GY     G 
Sbjct: 665 CKCPVGYVLREDRRMCK-DEDECEEGKHDCTEKQMECKNLIGTYMCIC-GPGYQRRPDGE 722

Query: 407 RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            C  + NEC+    +C +G C +T G + C C
Sbjct: 723 GC-VDENECQTKPGICENGRCLNTRGSYTCEC 753



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
 Frame = +2

Query: 275 YTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDR 445
           YTG     D+DEC         G C++ V ++ C+C    +   +   CE +++EC+   
Sbjct: 195 YTG--LPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCE-DIDECQNGP 251

Query: 446 ALCGHGVCYDTYGGFVCACQP 508
               +  C +T G + C C+P
Sbjct: 252 VCQRNAECINTAGSYRCDCKP 272



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NV 424
           C C  G+   + +T   D++EC    AC NG  C + + ++ C C          +  +V
Sbjct: 309 CLCHTGFKTNDDQTMCLDINECE-RDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDV 366

Query: 425 NECEEDRA-LCGHGVCYDTYGGFVCAC 502
           +EC      LC +G C +T G F C C
Sbjct: 367 DECASGNGNLCRNGQCINTVGSFQCQC 393



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 25/65 (38%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
 Frame = +3

Query: 60  DPCASA-ACRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSCS 230
           D C     C+HG +C+    G Y C+CP GY   G  C   V  D   V  PC  NG+C 
Sbjct: 564 DECKEPDVCKHG-QCINTD-GSYRCECPFGYILAGNEC---VDTDECSVGNPC-GNGTCK 617

Query: 231 VPPGG 245
              GG
Sbjct: 618 NVIGG 622



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
 Frame = +3

Query: 3   YECHCTARYTGNN----CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
           + C C   +  N+    CE D  +      C+  A C+    G Y CDC PGY  T
Sbjct: 224 FRCECPVGFFYNDKLLVCE-DIDECQNGPVCQRNAECINTA-GSYRCDCKPGYRFT 277



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 34/107 (31%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
           ++C C   Y     G  C VD  + C     +      ++  G Y C CPPGY      C
Sbjct: 389 FQCQCNEGYEVAPDGRTC-VDINE-CLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC 446

Query: 165 E--LEVSLDP-LCVAGPCRN-NGS--CSVPPGGDTYSAPVR-QDTRV 284
           E   E   +P +C  G C N  GS  C  P G    S+  R QD R+
Sbjct: 447 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM 493


>AL355357-1|CAI16435.1|   95|Homo sapiens protein ( Human DNA
           sequence from clone RP11-69I22 on chromosome 6. ).
          Length = 95

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 32/82 (39%), Positives = 46/82 (56%)
 Frame = +2

Query: 263 CPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEED 442
           C PG++G+ CE +++ECS ++ CL+G  C D +N Y C C   G++G  CE   NE E  
Sbjct: 12  CLPGFSGQFCEININECS-SSPCLHGADCEDHINGYVCKC-QPGWSGHHCE---NELECI 66

Query: 443 RALCGHGVCYDTYGGFVCACQP 508
              C H +C +   G  C C P
Sbjct: 67  PNSCVHELCMENEPGSTCLCTP 88



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP-L 191
           C   ++G  CE++  + C+S+ C HGA C ED    Y C C PG+ G +CE E+   P  
Sbjct: 12  CLPGFSGQFCEININE-CSSSPCLHGADC-EDHINGYVCKCQPGWSGHHCENELECIPNS 69

Query: 192 CVAGPCRNN---GSCSVPPG 242
           CV   C  N    +C   PG
Sbjct: 70  CVHELCMENEPGSTCLCTPG 89



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
 Frame = +2

Query: 392 GYTGARCETNVNECEEDRALCGHGV-CYDTYGGFVCACQPATPG 520
           G++G  CE N+NEC      C HG  C D   G+VC CQP   G
Sbjct: 15  GFSGQFCEININECSSSP--CLHGADCEDHINGYVCKCQPGWSG 56



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   ++G++CE +    C   +C H   C+E+  G  +C C PG+
Sbjct: 46  YVCKCQPGWSGHHCENEL--ECIPNSCVH-ELCMENEPGS-TCLCTPGF 90



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 15/44 (34%), Positives = 26/44 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT 385
           +C C PG++G +CE ++ EC    +C++   C++     TC CT
Sbjct: 47  VCKCQPGWSGHHCENEL-ECI-PNSCVH-ELCMENEPGSTCLCT 87


>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C   GRC      YTC+C    +TG  CE +   
Sbjct: 1347 LRCRCPPGFTGDYCETEIDLCY-SDPCGANGRCRSREGGYTCEC-FEDFTGEHCEVDARS 1404

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCACQP 508
                  +C + G C +   GGF C C P
Sbjct: 1405 GRCANGVCKNGGTCVNLLIGGFHCVCPP 1432



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   +TG +CEVDA    CA+  C++G  CV    G + C CPPG Y   YCE+
Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 25/73 (34%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C+C   + G +CE++ +   
Sbjct: 1349 CRCPPGFTGDYCETEI-DLCYSDPCGANGRC-RSREGGYTCECFEDFTGEHCEVD-ARSG 1405

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1406 RCANGVCKNGGTC 1418



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/69 (42%), Positives = 35/69 (50%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRN 215
            + C+VD  DPC S+ C   +RC  D   DYSC C  GY G  C     +D  C   PC N
Sbjct: 1868 DGCDVD--DPCTSSPCPPNSRC-HDAWEDYSCVCDKGYLGINC-----VD-ACHLNPCEN 1918

Query: 216  NGSCSVPPG 242
             G+C   PG
Sbjct: 1919 MGACVRSPG 1927



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 20/41 (48%), Positives = 23/41 (56%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G YCE E+    LC + PC  NG C    GG T
Sbjct: 1349 CRCPPGFTGDYCETEID---LCYSDPCGANGRCRSREGGYT 1386



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G NC VDA   C    C +   CV        Y C+C P ++G YCE ++
Sbjct: 1894 YSCVCDKGYLGINC-VDA---CHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKL 1949

Query: 177  SL--------DPLCVAGPCRNNGSCSVPPGGD 248
             L        +P+C  GPC     C+V  G D
Sbjct: 1950 DLPCPRGWWGNPVC--GPCH----CAVSKGFD 1975



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC--ETNVNECEEDRALCGHGVCY 472
            DVD+   ++ C    RC DA  +Y+C C   GY G  C    ++N CE        G C 
Sbjct: 1871 DVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCVDACHLNPCE------NMGACV 1923

Query: 473  DTYG---GFVCACQPATPG 520
             + G   G+VC C P+  G
Sbjct: 1924 RSPGSPQGYVCECGPSHYG 1942



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY G NC   VD C     C N G CV    +   Y C+C  + Y G  CE N  
Sbjct: 1896 CVCDKGYLGINC---VDACH-LNPCENMGACVRSPGSPQGYVCECGPSHY-GPYCE-NKL 1949

Query: 428  ECEEDRALCGHGVC 469
            +    R   G+ VC
Sbjct: 1950 DLPCPRGWWGNPVC 1963



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 17/46 (36%), Positives = 21/46 (45%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C    + C G   C NGG CV+  N Y C+C    + G  CE
Sbjct: 1642 TREGCAARRNFCDGRR-CQNGGTCVNRWNMYLCECPLR-FGGKNCE 1685


>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C   GRC      YTC+C    +TG  CE +   
Sbjct: 1347 LRCRCPPGFTGDYCETEIDLCY-SDPCGANGRCRSREGGYTCEC-FEDFTGEHCEVDARS 1404

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCACQP 508
                  +C + G C +   GGF C C P
Sbjct: 1405 GRCANGVCKNGGTCVNLLIGGFHCVCPP 1432



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   +TG +CEVDA    CA+  C++G  CV    G + C CPPG Y   YCE+
Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 25/73 (34%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C+C   + G +CE++ +   
Sbjct: 1349 CRCPPGFTGDYCETEI-DLCYSDPCGANGRC-RSREGGYTCECFEDFTGEHCEVD-ARSG 1405

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1406 RCANGVCKNGGTC 1418



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/69 (42%), Positives = 35/69 (50%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRN 215
            + C+VD  DPC S+ C   +RC  D   DYSC C  GY G  C     +D  C   PC N
Sbjct: 1868 DGCDVD--DPCTSSPCPPNSRC-HDAWEDYSCVCDKGYLGINC-----VD-ACHLNPCEN 1918

Query: 216  NGSCSVPPG 242
             G+C   PG
Sbjct: 1919 MGACVRSPG 1927



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 20/41 (48%), Positives = 23/41 (56%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G YCE E+    LC + PC  NG C    GG T
Sbjct: 1349 CRCPPGFTGDYCETEID---LCYSDPCGANGRCRSREGGYT 1386



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G NC VDA   C    C +   CV        Y C+C P ++G YCE ++
Sbjct: 1894 YSCVCDKGYLGINC-VDA---CHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKL 1949

Query: 177  SL--------DPLCVAGPCRNNGSCSVPPGGD 248
             L        +P+C  GPC     C+V  G D
Sbjct: 1950 DLPCPRGWWGNPVC--GPCH----CAVSKGFD 1975



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC--ETNVNECEEDRALCGHGVCY 472
            DVD+   ++ C    RC DA  +Y+C C   GY G  C    ++N CE        G C 
Sbjct: 1871 DVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCVDACHLNPCE------NMGACV 1923

Query: 473  DTYG---GFVCACQPATPG 520
             + G   G+VC C P+  G
Sbjct: 1924 RSPGSPQGYVCECGPSHYG 1942



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY G NC   VD C     C N G CV    +   Y C+C  + Y G  CE N  
Sbjct: 1896 CVCDKGYLGINC---VDACH-LNPCENMGACVRSPGSPQGYVCECGPSHY-GPYCE-NKL 1949

Query: 428  ECEEDRALCGHGVC 469
            +    R   G+ VC
Sbjct: 1950 DLPCPRGWWGNPVC 1963



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 17/46 (36%), Positives = 21/46 (45%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C    + C G   C NGG CV+  N Y C+C    + G  CE
Sbjct: 1642 TREGCAARRNFCDGRR-CQNGGTCVNRWNMYLCECPLR-FGGKNCE 1685


>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C   GRC      YTC+C    +TG  CE +   
Sbjct: 1347 LRCRCPPGFTGDYCETEIDLCY-SDPCGANGRCRSREGGYTCEC-FEDFTGEHCEVDARS 1404

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCACQP 508
                  +C + G C +   GGF C C P
Sbjct: 1405 GRCANGVCKNGGTCVNLLIGGFHCVCPP 1432



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   +TG +CEVDA    CA+  C++G  CV    G + C CPPG Y   YCE+
Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 25/73 (34%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C+C   + G +CE++ +   
Sbjct: 1349 CRCPPGFTGDYCETEI-DLCYSDPCGANGRC-RSREGGYTCECFEDFTGEHCEVD-ARSG 1405

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1406 RCANGVCKNGGTC 1418



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/69 (42%), Positives = 35/69 (50%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRN 215
            + C+VD  DPC S+ C   +RC  D   DYSC C  GY G  C     +D  C   PC N
Sbjct: 1868 DGCDVD--DPCTSSPCPPNSRC-HDAWEDYSCVCDKGYLGINC-----VD-ACHLNPCEN 1918

Query: 216  NGSCSVPPG 242
             G+C   PG
Sbjct: 1919 MGACVRSPG 1927



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 20/41 (48%), Positives = 23/41 (56%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G YCE E+    LC + PC  NG C    GG T
Sbjct: 1349 CRCPPGFTGDYCETEID---LCYSDPCGANGRCRSREGGYT 1386



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G NC VDA   C    C +   CV        Y C+C P ++G YCE ++
Sbjct: 1894 YSCVCDKGYLGINC-VDA---CHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKL 1949

Query: 177  SL--------DPLCVAGPCRNNGSCSVPPGGD 248
             L        +P+C  GPC     C+V  G D
Sbjct: 1950 DLPCPRGWWGNPVC--GPCH----CAVSKGFD 1975



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC--ETNVNECEEDRALCGHGVCY 472
            DVD+   ++ C    RC DA  +Y+C C   GY G  C    ++N CE        G C 
Sbjct: 1871 DVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCVDACHLNPCE------NMGACV 1923

Query: 473  DTYG---GFVCACQPATPG 520
             + G   G+VC C P+  G
Sbjct: 1924 RSPGSPQGYVCECGPSHYG 1942



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY G NC   VD C     C N G CV    +   Y C+C  + Y G  CE N  
Sbjct: 1896 CVCDKGYLGINC---VDACH-LNPCENMGACVRSPGSPQGYVCECGPSHY-GPYCE-NKL 1949

Query: 428  ECEEDRALCGHGVC 469
            +    R   G+ VC
Sbjct: 1950 DLPCPRGWWGNPVC 1963



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 17/46 (36%), Positives = 21/46 (45%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C    + C G   C NGG CV+  N Y C+C    + G  CE
Sbjct: 1642 TREGCAARRNFCDGRR-CQNGGTCVNRWNMYLCECPLR-FGGKNCE 1685


>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
            protein.
          Length = 3014

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C   GRC      YTC+C    +TG  CE +   
Sbjct: 1347 LRCRCPPGFTGDYCETEIDLCY-SDPCGANGRCRSREGGYTCEC-FEDFTGEHCEVDARS 1404

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCACQP 508
                  +C + G C +   GGF C C P
Sbjct: 1405 GRCANGVCKNGGTCVNLLIGGFHCVCPP 1432



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   +TG +CEVDA    CA+  C++G  CV    G + C CPPG Y   YCE+
Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 25/73 (34%), Positives = 37/73 (50%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C+C   + G +CE++ +   
Sbjct: 1349 CRCPPGFTGDYCETEI-DLCYSDPCGANGRC-RSREGGYTCECFEDFTGEHCEVD-ARSG 1405

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1406 RCANGVCKNGGTC 1418



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 29/69 (42%), Positives = 35/69 (50%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRN 215
            + C+VD  DPC S+ C   +RC  D   DYSC C  GY G  C     +D  C   PC N
Sbjct: 1868 DGCDVD--DPCTSSPCPPNSRC-HDAWEDYSCVCDKGYLGINC-----VD-ACHLNPCEN 1918

Query: 216  NGSCSVPPG 242
             G+C   PG
Sbjct: 1919 MGACVRSPG 1927



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 20/41 (48%), Positives = 23/41 (56%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G YCE E+    LC + PC  NG C    GG T
Sbjct: 1349 CRCPPGFTGDYCETEID---LCYSDPCGANGRCRSREGGYT 1386



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G NC VDA   C    C +   CV        Y C+C P ++G YCE ++
Sbjct: 1894 YSCVCDKGYLGINC-VDA---CHLNPCENMGACVRSPGSPQGYVCECGPSHYGPYCENKL 1949

Query: 177  SL--------DPLCVAGPCRNNGSCSVPPGGD 248
             L        +P+C  GPC     C+V  G D
Sbjct: 1950 DLPCPRGWWGNPVC--GPCH----CAVSKGFD 1975



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC--ETNVNECEEDRALCGHGVCY 472
            DVD+   ++ C    RC DA  +Y+C C   GY G  C    ++N CE        G C 
Sbjct: 1871 DVDDPCTSSPCPPNSRCHDAWEDYSCVCD-KGYLGINCVDACHLNPCE------NMGACV 1923

Query: 473  DTYG---GFVCACQPATPG 520
             + G   G+VC C P+  G
Sbjct: 1924 RSPGSPQGYVCECGPSHYG 1942



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 27/74 (36%), Positives = 32/74 (43%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCV---DAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY G NC   VD C     C N G CV    +   Y C+C  + Y G  CE N  
Sbjct: 1896 CVCDKGYLGINC---VDACH-LNPCENMGACVRSPGSPQGYVCECGPSHY-GPYCE-NKL 1949

Query: 428  ECEEDRALCGHGVC 469
            +    R   G+ VC
Sbjct: 1950 DLPCPRGWWGNPVC 1963



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 17/46 (36%), Positives = 21/46 (45%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C    + C G   C NGG CV+  N Y C+C    + G  CE
Sbjct: 1642 TREGCAARRNFCDGRR-CQNGGTCVNRWNMYLCECPLR-FGGKNCE 1685


>D89629-1|BAB46925.1|  815|Homo sapiens cerebral protein-12 protein.
          Length = 815

 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 10/93 (10%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGY--------TGA 406
           +C CP G+TG +CETD+DECS G   C +   C++    Y C+C   GY        +G 
Sbjct: 539 VCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCEC-RDGYHDNGMFSPSGE 597

Query: 407 RCETNVNECEEDRALCGHG-VCYDTYGGFVCAC 502
            CE +++EC   R  C +  +C++  GG+ C C
Sbjct: 598 SCE-DIDECGTGRHSCANDTICFNLDGGYDCRC 629



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRN-----CETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGA--- 406
           +C+C  G+         CE D+DEC+ G   C     CV+   ++ C C  TGY      
Sbjct: 420 VCSCRDGFRALREDNAYCE-DIDECAEGRHYCRENTMCVNTPGSFMCICK-TGYIRIDDY 477

Query: 407 RCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCRRVRQD 556
            C T  +EC  ++  C  + +C++T GG  C C+P   G+  T C+   +D
Sbjct: 478 SC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGN-GTTCKAFCKD 526



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYH--GTYCELEV 176
           C C   +TG +CE D  D C+     C   A C+ +  G Y C+C  GYH  G +     
Sbjct: 540 CACPQGFTGPSCETDI-DECSDGFVQCDSRANCI-NLPGWYHCECRDGYHDNGMFSPSGE 597

Query: 177 SLDPL--CVAG--PCRNNGSCSVPPGG 245
           S + +  C  G   C N+  C    GG
Sbjct: 598 SCEDIDECGTGRHSCANDTICFNLDGG 624



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTGN     A   C    CR+G  C+        C CP G+ G  CE ++  
Sbjct: 505 HNCVCKPGYTGNGTTCKAF--CKDG-CRNGGACIAAN----VCACPQGFTGPSCETDID- 556

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C +  +C   PG
Sbjct: 557 --ECSDGFVQCDSRANCINLPG 576



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSC 227
           C   A C     G ++C C PGY  +GT C+        C  G CRN G+C
Sbjct: 492 CDENALCFNTV-GGHNCVCKPGYTGNGTTCK------AFCKDG-CRNGGAC 534


>D83018-1|BAA11681.1|  816|Homo sapiens nel-related protein 2
           protein.
          Length = 816

 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 10/93 (10%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGY--------TGA 406
           +C CP G+TG +CETD+DECS G   C +   C++    Y C+C   GY        +G 
Sbjct: 540 VCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCEC-RDGYHDNGMFSPSGE 598

Query: 407 RCETNVNECEEDRALCGHG-VCYDTYGGFVCAC 502
            CE +++EC   R  C +  +C++  GG+ C C
Sbjct: 599 SCE-DIDECGTGRHSCANDTICFNLDGGYDCRC 630



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRN-----CETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGA--- 406
           +C+C  G+         CE D+DEC+ G   C     CV+   ++ C C  TGY      
Sbjct: 421 VCSCRDGFRALREDNAYCE-DIDECAEGRHYCRENTMCVNTPGSFMCICK-TGYIRIDDY 478

Query: 407 RCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCRRVRQD 556
            C T  +EC  ++  C  + +C++T GG  C C+P   G+  T C+   +D
Sbjct: 479 SC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGN-GTTCKAFCKD 527



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYH--GTYCELEV 176
           C C   +TG +CE D  D C+     C   A C+ +  G Y C+C  GYH  G +     
Sbjct: 541 CACPQGFTGPSCETDI-DECSDGFVQCDSRANCI-NLPGWYHCECRDGYHDNGMFSPSGE 598

Query: 177 SLDPL--CVAG--PCRNNGSCSVPPGG 245
           S + +  C  G   C N+  C    GG
Sbjct: 599 SCEDIDECGTGRHSCANDTICFNLDGG 625



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTGN     A   C    CR+G  C+        C CP G+ G  CE ++  
Sbjct: 506 HNCVCKPGYTGNGTTCKAF--CKDG-CRNGGACIAAN----VCACPQGFTGPSCETDID- 557

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C +  +C   PG
Sbjct: 558 --ECSDGFVQCDSRANCINLPG 577



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSC 227
           C   A C     G ++C C PGY  +GT C+        C  G CRN G+C
Sbjct: 493 CDENALCFNTV-GGHNCVCKPGYTGNGTTCK------AFCKDG-CRNGGAC 535


>BC020544-1|AAH20544.1|  816|Homo sapiens NELL2 protein protein.
          Length = 816

 Score = 68.9 bits (161), Expect = 1e-11
 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 10/93 (10%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGY--------TGA 406
           +C CP G+TG +CETD+DECS G   C +   C++    Y C+C   GY        +G 
Sbjct: 540 VCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCEC-RDGYHDNGMFSPSGE 598

Query: 407 RCETNVNECEEDRALCGHG-VCYDTYGGFVCAC 502
            CE +++EC   R  C +  +C++  GG+ C C
Sbjct: 599 SCE-DIDECGTGRHSCANDTICFNLDGGYDCRC 630



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
 Frame = +2

Query: 254 LCTCPPGYTGRN-----CETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGA--- 406
           +C+C  G+         CE D+DEC+ G   C     CV+   ++ C C  TGY      
Sbjct: 421 VCSCRDGFRALREDNAYCE-DIDECAEGRHYCRENTMCVNTPGSFMCICK-TGYIRIDDY 478

Query: 407 RCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCRRVRQD 556
            C T  +EC  ++  C  + +C++T GG  C C+P   G+  T C+   +D
Sbjct: 479 SC-TEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGN-GTTCKAFCKD 527



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 8/87 (9%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASA--ACRHGARCVEDGRGDYSCDCPPGYH--GTYCELEV 176
           C C   +TG +CE D  D C+     C   A C+ +  G Y C+C  GYH  G +     
Sbjct: 541 CACPQGFTGPSCETDI-DECSDGFVQCDSRANCI-NLPGWYHCECRDGYHDNGMFSPSGE 598

Query: 177 SLDPL--CVAG--PCRNNGSCSVPPGG 245
           S + +  C  G   C N+  C    GG
Sbjct: 599 SCEDIDECGTGRHSCANDTICFNLDGG 625



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   YTGN     A   C    CR+G  C+        C CP G+ G  CE ++  
Sbjct: 506 HNCVCKPGYTGNGTTCKAF--CKDG-CRNGGACIAAN----VCACPQGFTGPSCETDID- 557

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C +  +C   PG
Sbjct: 558 --ECSDGFVQCDSRANCINLPG 577



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGY--HGTYCELEVSLDPLCVAGPCRNNGSC 227
           C   A C     G ++C C PGY  +GT C+        C  G CRN G+C
Sbjct: 493 CDENALCFNTV-GGHNCVCKPGYTGNGTTCK------AFCKDG-CRNGGAC 535


>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
          Length = 2854

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 36/86 (41%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET+VD C  +  C   GRC      YTC C   GYTG  CE +   
Sbjct: 1203 LRCRCPPGFTGDYCETEVDLCY-SRPCGPHGRCRSREGGYTCLC-RDGYTGEHCEVSARS 1260

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCAC 502
                  +C + G C +   GGF C C
Sbjct: 1261 GRCTPGVCKNGGTCVNLLVGGFKCDC 1286



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 27/73 (36%), Positives = 36/73 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C C  GY G +CE+  +   
Sbjct: 1205 CRCPPGFTGDYCETEV-DLCYSRPCGPHGRC-RSREGGYTCLCRDGYTGEHCEVS-ARSG 1261

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1262 RCTPGVCKNGGTC 1274



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   YTG +CEV A    C    C++G  CV    G + CDCP G +   YC++
Sbjct: 1241 YTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQV 1298



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G+NC     + C    C H + C         Y+C+CPP Y G YCE  +
Sbjct: 1746 YSCSCDPGYYGDNCT----NVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRI 1801

Query: 177  SLDPLCVAG----PCRNNGSCSVPPGGD 248
              D  C  G    P     +C V  G D
Sbjct: 1802 --DQPCPRGWWGHPTCGPCNCDVSKGFD 1827



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            C+C PGY G NC    D++ C   + C    R   A + YTC+C    Y G  CET +++
Sbjct: 1748 CSCDPGYYGDNCTNVCDLNPCEHQSVCT---RKPSAPHGYTCEC-PPNYLGPYCETRIDQ 1803

Query: 431  -CEEDRALCGHGVC 469
             C   R   GH  C
Sbjct: 1804 PC--PRGWWGHPTC 1815



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%)
 Frame = +3

Query: 117  GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            G   C CPPG+ G YCE EV    LC + PC  +G C    GG T
Sbjct: 1201 GGLRCRCPPGFTGDYCETEVD---LCYSRPCGPHGRCRSREGGYT 1242



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
            R +  V    C C   G+TG  CET V+ C      CG HG C    GG+ C C+    G
Sbjct: 1195 RPIHPVGGLRCRCPP-GFTGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCRDGYTG 1251



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C +G  CV      +SC+CP G+ G  C  E++
Sbjct: 1509 CDSNTCHNGGTCVNQWDA-FSCECPLGFGGKSCAQEMA 1545



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 5/98 (5%)
 Frame = +2

Query: 230  RAPRRRH-LLCTCPPGYTGRNCETDVDE-C-SGAAACLNGGRC-VDAVNNYTCDCTATGY 397
            R P   H   C CPP Y G  CET +D+ C  G       G C  D    +  DC     
Sbjct: 1776 RKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNK--- 1832

Query: 398  TGARCETNVNECEEDRA-LCGHGVCYDTYGGFVCACQP 508
            T   C    N      +  C    CY T G     C P
Sbjct: 1833 TSGECHCKENHYRPPGSPTCLLCDCYPT-GSLSRVCDP 1869



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 13/41 (31%), Positives = 21/41 (51%)
 Frame = +2

Query: 290  CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C    + C  +  C NGG CV+  + ++C+C   G+ G  C
Sbjct: 1502 CPAKKNVCD-SNTCHNGGTCVNQWDAFSCEC-PLGFGGKSC 1540


>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 2 (flamingo homolog, Drosophila) protein.
          Length = 2923

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 36/86 (41%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET+VD C  +  C   GRC      YTC C   GYTG  CE +   
Sbjct: 1272 LRCRCPPGFTGDYCETEVDLCY-SRPCGPHGRCRSREGGYTCLC-RDGYTGEHCEVSARS 1329

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCAC 502
                  +C + G C +   GGF C C
Sbjct: 1330 GRCTPGVCKNGGTCVNLLVGGFKCDC 1355



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 27/73 (36%), Positives = 36/73 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C C  GY G +CE+  +   
Sbjct: 1274 CRCPPGFTGDYCETEV-DLCYSRPCGPHGRC-RSREGGYTCLCRDGYTGEHCEVS-ARSG 1330

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1331 RCTPGVCKNGGTC 1343



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   YTG +CEV A    C    C++G  CV    G + CDCP G +   YC++
Sbjct: 1310 YTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQV 1367



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G+NC     + C    C H + C         Y+C+CPP Y G YCE  +
Sbjct: 1815 YSCSCDPGYYGDNCT----NVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRI 1870

Query: 177  SLDPLCVAG----PCRNNGSCSVPPGGD 248
              D  C  G    P     +C V  G D
Sbjct: 1871 --DQPCPRGWWGHPTCGPCNCDVSKGFD 1896



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            C+C PGY G NC    D++ C   + C    R   A + YTC+C    Y G  CET +++
Sbjct: 1817 CSCDPGYYGDNCTNVCDLNPCEHQSVCT---RKPSAPHGYTCEC-PPNYLGPYCETRIDQ 1872

Query: 431  -CEEDRALCGHGVC 469
             C   R   GH  C
Sbjct: 1873 PC--PRGWWGHPTC 1884



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%)
 Frame = +3

Query: 117  GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            G   C CPPG+ G YCE EV    LC + PC  +G C    GG T
Sbjct: 1270 GGLRCRCPPGFTGDYCETEVD---LCYSRPCGPHGRCRSREGGYT 1311



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
            R +  V    C C   G+TG  CET V+ C      CG HG C    GG+ C C+    G
Sbjct: 1264 RPIHPVGGLRCRCPP-GFTGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCRDGYTG 1320



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C +G  CV      +SC+CP G+ G  C  E++
Sbjct: 1578 CDSNTCHNGGTCVNQWDA-FSCECPLGFGGKSCAQEMA 1614



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 5/98 (5%)
 Frame = +2

Query: 230  RAPRRRH-LLCTCPPGYTGRNCETDVDE-C-SGAAACLNGGRC-VDAVNNYTCDCTATGY 397
            R P   H   C CPP Y G  CET +D+ C  G       G C  D    +  DC     
Sbjct: 1845 RKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNK--- 1901

Query: 398  TGARCETNVNECEEDRA-LCGHGVCYDTYGGFVCACQP 508
            T   C    N      +  C    CY T G     C P
Sbjct: 1902 TSGECHCKENHYRPPGSPTCLLCDCYPT-GSLSRVCDP 1938



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 13/41 (31%), Positives = 21/41 (51%)
 Frame = +2

Query: 290  CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C    + C  +  C NGG CV+  + ++C+C   G+ G  C
Sbjct: 1571 CPAKKNVCD-SNTCHNGGTCVNQWDAFSCEC-PLGFGGKSC 1609


>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
          Length = 2923

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 36/86 (41%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET+VD C  +  C   GRC      YTC C   GYTG  CE +   
Sbjct: 1272 LRCRCPPGFTGDYCETEVDLCY-SRPCGPHGRCRSREGGYTCLC-RDGYTGEHCEVSARS 1329

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCAC 502
                  +C + G C +   GGF C C
Sbjct: 1330 GRCTPGVCKNGGTCVNLLVGGFKCDC 1355



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 27/73 (36%), Positives = 36/73 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C C  GY G +CE+  +   
Sbjct: 1274 CRCPPGFTGDYCETEV-DLCYSRPCGPHGRC-RSREGGYTCLCRDGYTGEHCEVS-ARSG 1330

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1331 RCTPGVCKNGGTC 1343



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   YTG +CEV A    C    C++G  CV    G + CDCP G +   YC++
Sbjct: 1310 YTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQV 1367



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G+NC     + C    C H + C         Y+C+CPP Y G YCE  +
Sbjct: 1815 YSCSCDPGYYGDNCT----NVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRI 1870

Query: 177  SLDPLCVAG----PCRNNGSCSVPPGGD 248
              D  C  G    P     +C V  G D
Sbjct: 1871 --DQPCPRGWWGHPTCGPCNCDVSKGFD 1896



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            C+C PGY G NC    D++ C   + C    R   A + YTC+C    Y G  CET +++
Sbjct: 1817 CSCDPGYYGDNCTNVCDLNPCEHQSVCT---RKPSAPHGYTCEC-PPNYLGPYCETRIDQ 1872

Query: 431  -CEEDRALCGHGVC 469
             C   R   GH  C
Sbjct: 1873 PC--PRGWWGHPTC 1884



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%)
 Frame = +3

Query: 117  GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            G   C CPPG+ G YCE EV    LC + PC  +G C    GG T
Sbjct: 1270 GGLRCRCPPGFTGDYCETEVD---LCYSRPCGPHGRCRSREGGYT 1311



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
            R +  V    C C   G+TG  CET V+ C      CG HG C    GG+ C C+    G
Sbjct: 1264 RPIHPVGGLRCRCPP-GFTGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCRDGYTG 1320



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C +G  CV      +SC+CP G+ G  C  E++
Sbjct: 1578 CDSNTCHNGGTCVNQWDA-FSCECPLGFGGKSCAQEMA 1614



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 5/98 (5%)
 Frame = +2

Query: 230  RAPRRRH-LLCTCPPGYTGRNCETDVDE-C-SGAAACLNGGRC-VDAVNNYTCDCTATGY 397
            R P   H   C CPP Y G  CET +D+ C  G       G C  D    +  DC     
Sbjct: 1845 RKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNK--- 1901

Query: 398  TGARCETNVNECEEDRA-LCGHGVCYDTYGGFVCACQP 508
            T   C    N      +  C    CY T G     C P
Sbjct: 1902 TSGECHCKENHYRPPGSPTCLLCDCYPT-GSLSRVCDP 1938



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 13/41 (31%), Positives = 21/41 (51%)
 Frame = +2

Query: 290  CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C    + C  +  C NGG CV+  + ++C+C   G+ G  C
Sbjct: 1571 CPAKKNVCD-SNTCHNGGTCVNQWDAFSCEC-PLGFGGKSC 1609


>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
            receptor protein.
          Length = 2923

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 36/86 (41%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET+VD C  +  C   GRC      YTC C   GYTG  CE +   
Sbjct: 1272 LRCRCPPGFTGDYCETEVDLCY-SRPCGPHGRCRSREGGYTCLC-RDGYTGEHCEVSARS 1329

Query: 431  CEEDRALCGH-GVCYD-TYGGFVCAC 502
                  +C + G C +   GGF C C
Sbjct: 1330 GRCTPGVCKNGGTCVNLLVGGFKCDC 1355



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 27/73 (36%), Positives = 36/73 (49%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  C    RC     G Y+C C  GY G +CE+  +   
Sbjct: 1274 CRCPPGFTGDYCETEV-DLCYSRPCGPHGRC-RSREGGYTCLCRDGYTGEHCEVS-ARSG 1330

Query: 189  LCVAGPCRNNGSC 227
             C  G C+N G+C
Sbjct: 1331 RCTPGVCKNGGTC 1343



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG-YHGTYCEL 170
            Y C C   YTG +CEV A    C    C++G  CV    G + CDCP G +   YC++
Sbjct: 1310 YTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQV 1367



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGD--YSCDCPPGYHGTYCELEV 176
            Y C C   Y G+NC     + C    C H + C         Y+C+CPP Y G YCE  +
Sbjct: 1815 YSCSCDPGYYGDNCT----NVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRI 1870

Query: 177  SLDPLCVAG----PCRNNGSCSVPPGGD 248
              D  C  G    P     +C V  G D
Sbjct: 1871 --DQPCPRGWWGHPTCGPCNCDVSKGFD 1896



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            C+C PGY G NC    D++ C   + C    R   A + YTC+C    Y G  CET +++
Sbjct: 1817 CSCDPGYYGDNCTNVCDLNPCEHQSVCT---RKPSAPHGYTCEC-PPNYLGPYCETRIDQ 1872

Query: 431  -CEEDRALCGHGVC 469
             C   R   GH  C
Sbjct: 1873 PC--PRGWWGHPTC 1884



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%)
 Frame = +3

Query: 117  GDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            G   C CPPG+ G YCE EV    LC + PC  +G C    GG T
Sbjct: 1270 GGLRCRCPPGFTGDYCETEVD---LCYSRPCGPHGRCRSREGGYT 1311



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
            R +  V    C C   G+TG  CET V+ C      CG HG C    GG+ C C+    G
Sbjct: 1264 RPIHPVGGLRCRCPP-GFTGDYCETEVDLCYSRP--CGPHGRCRSREGGYTCLCRDGYTG 1320



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C +G  CV      +SC+CP G+ G  C  E++
Sbjct: 1578 CDSNTCHNGGTCVNQWDA-FSCECPLGFGGKSCAQEMA 1614



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 30/98 (30%), Positives = 34/98 (34%), Gaps = 5/98 (5%)
 Frame = +2

Query: 230  RAPRRRH-LLCTCPPGYTGRNCETDVDE-C-SGAAACLNGGRC-VDAVNNYTCDCTATGY 397
            R P   H   C CPP Y G  CET +D+ C  G       G C  D    +  DC     
Sbjct: 1845 RKPSAPHGYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNK--- 1901

Query: 398  TGARCETNVNECEEDRA-LCGHGVCYDTYGGFVCACQP 508
            T   C    N      +  C    CY T G     C P
Sbjct: 1902 TSGECHCKENHYRPPGSPTCLLCDCYPT-GSLSRVCDP 1938



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 13/41 (31%), Positives = 21/41 (51%)
 Frame = +2

Query: 290  CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC 412
            C    + C  +  C NGG CV+  + ++C+C   G+ G  C
Sbjct: 1571 CPAKKNVCD-SNTCHNGGTCVNQWDAFSCEC-PLGFGGKSC 1609


>X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA for
            the chondroitin sulphate proteoglycan versican,  V1
            splice-variant; precursor peptide.  ).
          Length = 2409

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236  PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 2119 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 2176

Query: 416  TNVNECE 436
             +   C+
Sbjct: 2177 QDTETCD 2183



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 2124 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 2180

Query: 183  DPLCVAGPCRNNGSC 227
               C  G  +  G C
Sbjct: 2181 --TCDYGWHKFQGQC 2193



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 33/65 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C D +  F C C P
Sbjct: 2111 CLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATCVDGFNTFRCLCLP 2168

Query: 509  ATPGS 523
            +  G+
Sbjct: 2169 SYVGA 2173



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 2104 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 2155


>U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein
            precursor protein.
          Length = 1642

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236  PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 1352 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 1409

Query: 416  TNVNECE 436
             +   C+
Sbjct: 1410 QDTETCD 1416



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 1357 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 1413

Query: 183  DPLCVAGPCRNNGSC 227
               C  G  +  G C
Sbjct: 1414 --TCDYGWHKFQGQC 1426



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 28/80 (35%), Positives = 38/80 (47%)
 Frame = +2

Query: 284  RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHG 463
            R  +T  D C     CLNGG C     +Y C C   GY+G +CE + +EC  +    G  
Sbjct: 1330 RENKTGPDRCK-MNPCLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-A 1386

Query: 464  VCYDTYGGFVCACQPATPGS 523
             C D +  F C C P+  G+
Sbjct: 1387 TCVDGFNTFRCLCLPSYVGA 1406



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 1337 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 1388


>U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate
            proteoglycan versican V0 splice-variant precursor peptide
            protein.
          Length = 3396

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236  PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 3106 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 3163

Query: 416  TNVNECE 436
             +   C+
Sbjct: 3164 QDTETCD 3170



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 3111 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 3167

Query: 183  DPLCVAGPCRNNGSC 227
               C  G  +  G C
Sbjct: 3168 --TCDYGWHKFQGQC 3180



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 33/65 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C D +  F C C P
Sbjct: 3098 CLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATCVDGFNTFRCLCLP 3155

Query: 509  ATPGS 523
            +  G+
Sbjct: 3156 SYVGA 3160



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 3091 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 3142


>J02814-1|AAA36437.1|  688|Homo sapiens protein ( Human chondroitin
           sulfate proteoglycan core protein mRNA, 3' end. ).
          Length = 688

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 398 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 455

Query: 416 TNVNECE 436
            +   C+
Sbjct: 456 QDTETCD 462



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 403 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 459

Query: 183 DPLCVAGPCRNNGSC 227
              C  G  +  G C
Sbjct: 460 --TCDYGWHKFQGQC 472



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 33/65 (50%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C D +  F C C P
Sbjct: 390 CLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATCVDGFNTFRCLCLP 447

Query: 509 ATPGS 523
           +  G+
Sbjct: 448 SYVGA 452



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 383 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 434


>D32039-1|BAA06801.1|  655|Homo sapiens proteoglycan PG-M(V3)
           protein.
          Length = 655

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236 PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 365 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 422

Query: 416 TNVNECE 436
            +   C+
Sbjct: 423 QDTETCD 429



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 370 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 426

Query: 183 DPLCVAGPCRNNGSC 227
              C  G  +  G C
Sbjct: 427 --TCDYGWHKFQGQC 439



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/78 (34%), Positives = 36/78 (46%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVC 469
           C    D C     CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C
Sbjct: 345 CFKRPDRCK-MNPCLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATC 401

Query: 470 YDTYGGFVCACQPATPGS 523
            D +  F C C P+  G+
Sbjct: 402 VDGFNTFRCLCLPSYVGA 419



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 350 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 401


>BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein
            protein.
          Length = 2060

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236  PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 1770 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 1827

Query: 416  TNVNECE 436
             +   C+
Sbjct: 1828 QDTETCD 1834



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 1775 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 1831

Query: 183  DPLCVAGPCRNNGSC 227
               C  G  +  G C
Sbjct: 1832 --TCDYGWHKFQGQC 1844



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 33/65 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C D +  F C C P
Sbjct: 1762 CLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATCVDGFNTFRCLCLP 1819

Query: 509  ATPGS 523
            +  G+
Sbjct: 1820 SYVGA 1824



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 1755 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 1806


>AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate
            proteoglycan 2 (versican) variant protein.
          Length = 3410

 Score = 68.1 bits (159), Expect = 2e-11
 Identities = 29/67 (43%), Positives = 36/67 (53%)
 Frame = +2

Query: 236  PRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            P     +CTC PGY+G  CE D DEC  +  C NG  CVD  N + C C  + Y GA CE
Sbjct: 3120 PTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTFRCLCLPS-YVGALCE 3177

Query: 416  TNVNECE 436
             +   C+
Sbjct: 3178 QDTETCD 3184



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/75 (40%), Positives = 37/75 (49%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C   Y+G+ CE+D  D C S  CR+GA CV DG   + C C P Y G  CE +   
Sbjct: 3125 YVCTCVPGYSGDQCELDF-DECHSNPCRNGATCV-DGFNTFRCLCLPSYVGALCEQDTE- 3181

Query: 183  DPLCVAGPCRNNGSC 227
               C  G  +  G C
Sbjct: 3182 --TCDYGWHKFQGQC 3194



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 33/65 (50%)
 Frame = +2

Query: 329  CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            CLNGG C     +Y C C   GY+G +CE + +EC  +    G   C D +  F C C P
Sbjct: 3112 CLNGGTCYPTETSYVCTC-VPGYSGDQCELDFDECHSNPCRNG-ATCVDGFNTFRCLCLP 3169

Query: 509  ATPGS 523
            +  G+
Sbjct: 3170 SYVGA 3174



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 25/56 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D C    C +G  C       Y C C PGY G  CEL+      C + PCRN  +C
Sbjct: 3105 DRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFD---ECHSNPCRNGATC 3156


>AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.
          Length = 4186

 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 32/79 (40%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  CR+G  C     G Y+C C P + G  CEL+     
Sbjct: 1491 CRCPPGFTGDFCETEL-DLCYSNPCRNGGACARR-EGGYTCVCRPRFTGEDCELDTEAGR 1548

Query: 189  LCVAGPCRNNGSCSVPPGG 245
             CV G CRN G+C+  P G
Sbjct: 1549 -CVPGVCRNGGTCTDAPNG 1566



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 35/86 (40%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C NGG C      YTC C    +TG  CE +   
Sbjct: 1489 LRCRCPPGFTGDFCETELDLCY-SNPCRNGGACARREGGYTCVCRPR-FTGEDCELDTEA 1546

Query: 431  CEEDRALCGH-GVCYDT-YGGFVCAC 502
                  +C + G C D   GGF C C
Sbjct: 1547 GRCVPGVCRNGGTCTDAPNGGFRCQC 1572



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG--YHGTYCEL 170
            Y C C  R+TG +CE+D     C    CR+G  C +   G + C CP G  + G  CE+
Sbjct: 1527 YTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEV 1585



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
 Frame = +2

Query: 233  APRRRHLLCTCPPGYTGRNCETDVD--ECSGAAACLNGGRCVDAVN-NYTCDCTATG-YT 400
            A R     C C P +TG +CE D +   C     C NGG C DA N  + C C A G + 
Sbjct: 1521 ARREGGYTCVCRPRFTGEDCELDTEAGRCV-PGVCRNGGTCTDAPNGGFRCQCPAGGAFE 1579

Query: 401  GARCE 415
            G RCE
Sbjct: 1580 GPRCE 1584



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 20/41 (48%), Positives = 26/41 (63%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G +CE E+    LC + PCRN G+C+   GG T
Sbjct: 1491 CRCPPGFTGDFCETELD---LCYSNPCRNGGACARREGGYT 1528



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 34/89 (38%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTC PGY G  C   VD C     C N G C     A + YTCDC   GY G  CE  ++
Sbjct: 2040 CTCQPGYYGPGC---VDACL-LNPCQNQGSCRHLPGAPHGYTCDCVG-GYFGHHCEHRMD 2094

Query: 428  -ECEE---DRALCGHGVCYDTYGGFVCAC 502
             +C         CG   C D + GF   C
Sbjct: 2095 QQCPRGWWGSPTCGPCNC-DVHKGFDPNC 2122



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 25/59 (42%), Positives = 30/59 (50%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
            CAS  C   A C  D    +SC C PGY+G  C     +D  C+  PC+N GSC   PG
Sbjct: 2020 CASGPCPPHADC-RDLWQTFSCTCQPGYYGPGC-----VD-ACLLNPCQNQGSCRHLPG 2071



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG--DPCAS-AACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            + C C   Y G  C VDA   +PC +  +CRH    +      Y+CDC  GY G +CE  
Sbjct: 2038 FSCTCQPGYYGPGC-VDACLLNPCQNQGSCRH----LPGAPHGYTCDCVGGYFGHHCEHR 2092

Query: 174  VSLDPLCVAG----PCRNNGSCSVPPGGD 248
              +D  C  G    P     +C V  G D
Sbjct: 2093 --MDQQCPRGWWGSPTCGPCNCDVHKGFD 2119



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            R +  +    C C   G+TG  CET ++ C  +    G G C    GG+ C C+P   G
Sbjct: 1481 RPIQPIAGLRCRCPP-GFTGDFCETELDLCYSNPCRNG-GACARREGGYTCVCRPRFTG 1537



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C++   C E   G +SCDCP G+ G  C+L ++
Sbjct: 1796 CDSGPCKNSGFCSERW-GSFSCDCPVGFGGKDCQLTMA 1832



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/46 (28%), Positives = 22/46 (47%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C+  +  C  +  C N G C +   +++CDC   G+ G  C+
Sbjct: 1785 TMAGCQAKLHFCD-SGPCKNSGFCSERWGSFSCDC-PVGFGGKDCQ 1828


>AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1
            protein.
          Length = 3312

 Score = 67.7 bits (158), Expect = 3e-11
 Identities = 32/79 (40%), Positives = 41/79 (51%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG+ CE +  D C S  CR+G  C     G Y+C C P + G  CEL+     
Sbjct: 1421 CRCPPGFTGDFCETEL-DLCYSNPCRNGGACARR-EGGYTCVCRPRFTGEDCELDTEAGR 1478

Query: 189  LCVAGPCRNNGSCSVPPGG 245
             CV G CRN G+C+  P G
Sbjct: 1479 -CVPGVCRNGGTCTDAPNG 1496



 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 35/86 (40%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +2

Query: 251  LLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
            L C CPPG+TG  CET++D C  +  C NGG C      YTC C    +TG  CE +   
Sbjct: 1419 LRCRCPPGFTGDFCETELDLCY-SNPCRNGGACARREGGYTCVCRPR-FTGEDCELDTEA 1476

Query: 431  CEEDRALCGH-GVCYDT-YGGFVCAC 502
                  +C + G C D   GGF C C
Sbjct: 1477 GRCVPGVCRNGGTCTDAPNGGFRCQC 1502



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDA-GDPCASAACRHGARCVEDGRGDYSCDCPPG--YHGTYCEL 170
            Y C C  R+TG +CE+D     C    CR+G  C +   G + C CP G  + G  CE+
Sbjct: 1457 YTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTDAPNGGFRCQCPAGGAFEGPRCEV 1515



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
 Frame = +2

Query: 233  APRRRHLLCTCPPGYTGRNCETDVD--ECSGAAACLNGGRCVDAVN-NYTCDCTATG-YT 400
            A R     C C P +TG +CE D +   C     C NGG C DA N  + C C A G + 
Sbjct: 1451 ARREGGYTCVCRPRFTGEDCELDTEAGRCV-PGVCRNGGTCTDAPNGGFRCQCPAGGAFE 1509

Query: 401  GARCE 415
            G RCE
Sbjct: 1510 GPRCE 1514



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 20/41 (48%), Positives = 26/41 (63%)
 Frame = +3

Query: 129  CDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGGDT 251
            C CPPG+ G +CE E+    LC + PCRN G+C+   GG T
Sbjct: 1421 CRCPPGFTGDFCETELD---LCYSNPCRNGGACARREGGYT 1458



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 34/89 (38%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC---VDAVNNYTCDCTATGYTGARCETNVN 427
            CTC PGY G  C   VD C     C N G C     A + YTCDC   GY G  CE  ++
Sbjct: 1970 CTCQPGYYGPGC---VDACL-LNPCQNQGSCRHLPGAPHGYTCDCVG-GYFGHHCEHRMD 2024

Query: 428  -ECEE---DRALCGHGVCYDTYGGFVCAC 502
             +C         CG   C D + GF   C
Sbjct: 2025 QQCPRGWWGSPTCGPCNC-DVHKGFDPNC 2052



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 25/59 (42%), Positives = 30/59 (50%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPG 242
            CAS  C   A C  D    +SC C PGY+G  C     +D  C+  PC+N GSC   PG
Sbjct: 1950 CASGPCPPHADC-RDLWQTFSCTCQPGYYGPGC-----VD-ACLLNPCQNQGSCRHLPG 2001



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAG--DPCAS-AACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            + C C   Y G  C VDA   +PC +  +CRH    +      Y+CDC  GY G +CE  
Sbjct: 1968 FSCTCQPGYYGPGC-VDACLLNPCQNQGSCRH----LPGAPHGYTCDCVGGYFGHHCEHR 2022

Query: 174  VSLDPLCVAG----PCRNNGSCSVPPGGD 248
              +D  C  G    P     +C V  G D
Sbjct: 2023 --MDQQCPRGWWGSPTCGPCNCDVHKGFD 2049



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 19/59 (32%), Positives = 27/59 (45%)
 Frame = +2

Query: 344  RCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
            R +  +    C C   G+TG  CET ++ C  +    G G C    GG+ C C+P   G
Sbjct: 1411 RPIQPIAGLRCRCPP-GFTGDFCETELDLCYSNPCRNG-GACARREGGYTCVCRPRFTG 1467



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = +3

Query: 66   CASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVS 179
            C S  C++   C E   G +SCDCP G+ G  C+L ++
Sbjct: 1726 CDSGPCKNSGFCSERW-GSFSCDCPVGFGGKDCQLTMA 1762



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 13/46 (28%), Positives = 22/46 (47%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            T   C+  +  C  +  C N G C +   +++CDC   G+ G  C+
Sbjct: 1715 TMAGCQAKLHFCD-SGPCKNSGFCSERWGSFSCDC-PVGFGGKDCQ 1758


>BC110320-1|AAI10321.1|  383|Homo sapiens delta-like 2 homolog
           (Drosophila) protein.
          Length = 383

 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C + + G  C+ D       + C++G +C+ DG G+Y C C PG+HG  CE +   
Sbjct: 75  WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG- 133

Query: 183 DPLCVAG-PCRNNGSCSVPPG 242
            P   AG PCRN G C    G
Sbjct: 134 -PCEQAGSPCRNGGQCQDDQG 153



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CE +VD+C     C NG  C+D +N ++C C   G+ G  C  N+++C 
Sbjct: 160 CRCLVGFVGARCEVNVDDCL-MRPCANGATCLDGINRFSCLC-PEGFAGRFCTINLDDCA 217

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGST 526
                C  G  C D    F C C     G T
Sbjct: 218 S--RPCQRGARCRDRVHDFDCLCPSGYGGKT 246



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G+ C+ D   C+  + C NGG+C+ D    Y C C   G+ G  CE     C
Sbjct: 77  CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC-LPGFHGRDCERKAGPC 135

Query: 434 EEDRALCGH-GVCYDTYG---GFVCAC 502
           E+  + C + G C D  G    F C C
Sbjct: 136 EQAGSPCRNGGQCQDDQGFALNFTCRC 162



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEV+  D C    C +GA C+ DG   +SC CP G+ G +C   ++L
Sbjct: 158 FTCRCLVGFVGARCEVNVDD-CLMRPCANGATCL-DGINRFSCLCPEGFAGRFC--TINL 213

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC+    C
Sbjct: 214 DD-CASRPCQRGARC 227



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C ++  D CAS  C+ GARC  D   D+ C CP GY G  CEL + +
Sbjct: 196 FSCLCPEGFAGRFCTINLDD-CASRPCQRGARC-RDRVHDFDCLCPSGYGGKTCELVLPV 253

Query: 183 --DPLCVAGPCRNNGSCSVPPGG 245
              P  V  P     +  VP  G
Sbjct: 254 PDPPTTVDTPLGPTSAVVVPATG 276



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 5/80 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRG---DYSCDCPPGYHGTYCE 167
           Y C C   + G +CE  AG PC  A + CR+G +C +D +G   +++C C  G+ G  CE
Sbjct: 115 YHCVCLPGFHGRDCERKAG-PCEQAGSPCRNGGQC-QDDQGFALNFTCRCLVGFVGARCE 172

Query: 168 LEVSLDPLCVAGPCRNNGSC 227
           + V  D  C+  PC N  +C
Sbjct: 173 VNVD-D--CLMRPCANGATC 189



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C CP G+ GR C  ++D+C+ +  C  G RC D V+++ C C  +GY G  CE
Sbjct: 198 CLCPEGFAGRFCTINLDDCA-SRPCQRGARCRDRVHDFDCLC-PSGYGGKTCE 248



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE     C     C + G C      + C C  +G+ G  C+ + + C 
Sbjct: 46  CRCDPGWEGLHCE----RCVRMPGCQH-GTCHQP---WQCIC-HSGWAGKFCDKDEHICT 96

Query: 437 EDRALCGHGVC-YDTYGGFVCACQPATPG 520
                   G C YD  G + C C P   G
Sbjct: 97  TQSPCQNGGQCMYDGGGEYHCVCLPGFHG 125



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CE     P     C+HG  C +     + C C  G+ G +C+ +   + 
Sbjct: 46  CRCDPGWEGLHCERCVRMP----GCQHGT-CHQP----WQCICHSGWAGKFCDKD---EH 93

Query: 189 LCVA-GPCRNNGSCSVPPGGD 248
           +C    PC+N G C    GG+
Sbjct: 94  ICTTQSPCQNGGQCMYDGGGE 114



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C+S     HG  C  DG    SC C PG+ G +CE  V + P C  G C     C
Sbjct: 27  DDCSSHCDLAHGC-CAPDG----SCRCDPGWEGLHCERCVRM-PGCQHGTCHQPWQC 77


>AY358126-1|AAQ88493.1|  383|Homo sapiens PSGC2903 protein.
          Length = 383

 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C + + G  C+ D       + C++G +C+ DG G+Y C C PG+HG  CE +   
Sbjct: 75  WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG- 133

Query: 183 DPLCVAG-PCRNNGSCSVPPG 242
            P   AG PCRN G C    G
Sbjct: 134 -PCEQAGSPCRNGGQCQDDQG 153



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CE +VD+C     C NG  C+D +N ++C C   G+ G  C  N+++C 
Sbjct: 160 CRCLVGFVGARCEVNVDDCL-MRPCANGATCLDGINRFSCLC-PEGFAGRFCTINLDDCA 217

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGST 526
                C  G  C D    F C C     G T
Sbjct: 218 S--RPCQRGARCRDRVHDFDCLCPSGYGGKT 246



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G+ C+ D   C+  + C NGG+C+ D    Y C C   G+ G  CE     C
Sbjct: 77  CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC-LPGFHGRDCERKAGPC 135

Query: 434 EEDRALCGH-GVCYDTYG---GFVCAC 502
           E+  + C + G C D  G    F C C
Sbjct: 136 EQAGSPCRNGGQCQDDQGFALNFTCRC 162



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEV+  D C    C +GA C+ DG   +SC CP G+ G +C   ++L
Sbjct: 158 FTCRCLVGFVGARCEVNVDD-CLMRPCANGATCL-DGINRFSCLCPEGFAGRFC--TINL 213

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC+    C
Sbjct: 214 DD-CASRPCQRGARC 227



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C ++  D CAS  C+ GARC  D   D+ C CP GY G  CEL + +
Sbjct: 196 FSCLCPEGFAGRFCTINLDD-CASRPCQRGARC-RDRVHDFDCLCPSGYGGKTCELVLPV 253

Query: 183 --DPLCVAGPCRNNGSCSVPPGG 245
              P  V  P     +  VP  G
Sbjct: 254 PDPPTTVDTPLGPTSAVVVPATG 276



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 5/80 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRG---DYSCDCPPGYHGTYCE 167
           Y C C   + G +CE  AG PC  A + CR+G +C +D +G   +++C C  G+ G  CE
Sbjct: 115 YHCVCLPGFHGRDCERKAG-PCEQAGSPCRNGGQC-QDDQGFALNFTCRCLVGFVGARCE 172

Query: 168 LEVSLDPLCVAGPCRNNGSC 227
           + V  D  C+  PC N  +C
Sbjct: 173 VNVD-D--CLMRPCANGATC 189



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C CP G+ GR C  ++D+C+ +  C  G RC D V+++ C C  +GY G  CE
Sbjct: 198 CLCPEGFAGRFCTINLDDCA-SRPCQRGARCRDRVHDFDCLC-PSGYGGKTCE 248



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE     C     C + G C      + C C  +G+ G  C+ + + C 
Sbjct: 46  CRCDPGWEGLHCE----RCVRMPGCQH-GTCHQP---WQCIC-HSGWAGKFCDKDEHICT 96

Query: 437 EDRALCGHGVC-YDTYGGFVCACQPATPG 520
                   G C YD  G + C C P   G
Sbjct: 97  TQSPCQNGGQCMYDGGGEYHCVCLPGFHG 125



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CE     P     C+HG  C +     + C C  G+ G +C+ +   + 
Sbjct: 46  CRCDPGWEGLHCERCVRMP----GCQHGT-CHQP----WQCICHSGWAGKFCDKD---EH 93

Query: 189 LCVA-GPCRNNGSCSVPPGGD 248
           +C    PC+N G C    GG+
Sbjct: 94  ICTTQSPCQNGGQCMYDGGGE 114



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C+S     HG  C  DG    SC C PG+ G +CE  V + P C  G C     C
Sbjct: 27  DDCSSHCDLAHGC-CAPDG----SCRCDPGWEGLHCERCVRM-PGCQHGTCHQPWQC 77


>AL359813-9|CAI23224.1|  383|Homo sapiens EGF-like-domain, multiple
           9 protein.
          Length = 383

 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           ++C C + + G  C+ D       + C++G +C+ DG G+Y C C PG+HG  CE +   
Sbjct: 75  WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAG- 133

Query: 183 DPLCVAG-PCRNNGSCSVPPG 242
            P   AG PCRN G C    G
Sbjct: 134 -PCEQAGSPCRNGGQCQDDQG 153



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CE +VD+C     C NG  C+D +N ++C C   G+ G  C  N+++C 
Sbjct: 160 CRCLVGFVGARCEVNVDDCL-MRPCANGATCLDGINRFSCLC-PEGFAGRFCTINLDDCA 217

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGST 526
                C  G  C D    F C C     G T
Sbjct: 218 S--RPCQRGARCRDRVHDFDCLCPSGYGGKT 246



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCV-DAVNNYTCDCTATGYTGARCETNVNEC 433
           C C  G+ G+ C+ D   C+  + C NGG+C+ D    Y C C   G+ G  CE     C
Sbjct: 77  CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC-LPGFHGRDCERKAGPC 135

Query: 434 EEDRALCGH-GVCYDTYG---GFVCAC 502
           E+  + C + G C D  G    F C C
Sbjct: 136 EQAGSPCRNGGQCQDDQGFALNFTCRC 162



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEV+  D C    C +GA C+ DG   +SC CP G+ G +C   ++L
Sbjct: 158 FTCRCLVGFVGARCEVNVDD-CLMRPCANGATCL-DGINRFSCLCPEGFAGRFC--TINL 213

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC+    C
Sbjct: 214 DD-CASRPCQRGARC 227



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C ++  D CAS  C+ GARC  D   D+ C CP GY G  CEL + +
Sbjct: 196 FSCLCPEGFAGRFCTINLDD-CASRPCQRGARC-RDRVHDFDCLCPSGYGGKTCELVLPV 253

Query: 183 --DPLCVAGPCRNNGSCSVPPGG 245
              P  V  P     +  VP  G
Sbjct: 254 PDPPTTVDTPLGPTSAVVVPATG 276



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 5/80 (6%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRG---DYSCDCPPGYHGTYCE 167
           Y C C   + G +CE  AG PC  A + CR+G +C +D +G   +++C C  G+ G  CE
Sbjct: 115 YHCVCLPGFHGRDCERKAG-PCEQAGSPCRNGGQC-QDDQGFALNFTCRCLVGFVGARCE 172

Query: 168 LEVSLDPLCVAGPCRNNGSC 227
           + V  D  C+  PC N  +C
Sbjct: 173 VNVD-D--CLMRPCANGATC 189



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C CP G+ GR C  ++D+C+ +  C  G RC D V+++ C C  +GY G  CE
Sbjct: 198 CLCPEGFAGRFCTINLDDCA-SRPCQRGARCRDRVHDFDCLC-PSGYGGKTCE 248



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C PG+ G +CE     C     C + G C      + C C  +G+ G  C+ + + C 
Sbjct: 46  CRCDPGWEGLHCE----RCVRMPGCQH-GTCHQP---WQCIC-HSGWAGKFCDKDEHICT 96

Query: 437 EDRALCGHGVC-YDTYGGFVCACQPATPG 520
                   G C YD  G + C C P   G
Sbjct: 97  TQSPCQNGGQCMYDGGGEYHCVCLPGFHG 125



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 1/81 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G +CE     P     C+HG  C +     + C C  G+ G +C+ +   + 
Sbjct: 46  CRCDPGWEGLHCERCVRMP----GCQHGT-CHQP----WQCICHSGWAGKFCDKD---EH 93

Query: 189 LCVA-GPCRNNGSCSVPPGGD 248
           +C    PC+N G C    GG+
Sbjct: 94  ICTTQSPCQNGGQCMYDGGGE 114



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAA-CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D C+S     HG  C  DG    SC C PG+ G +CE  V + P C  G C     C
Sbjct: 27  DDCSSHCDLAHGC-CAPDG----SCRCDPGWEGLHCERCVRM-PGCQHGTCHQPWQC 77


>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
            protein protein.
          Length = 4590

 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 30/75 (40%), Positives = 40/75 (53%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
            Y C C+A Y G +CE+   +PC+S  C +G  CV D  G + C C   Y G  C+    L
Sbjct: 4038 YYCKCSALYIGTHCEISV-NPCSSNPCLYGGTCVVD-NGGFVCQCRGLYTGQRCQ----L 4091

Query: 183  DPLCVAGPCRNNGSC 227
             P C   PC+N G+C
Sbjct: 4092 SPYCKDEPCKNGGTC 4106



 Score = 62.9 bits (146), Expect = 9e-10
 Identities = 28/83 (33%), Positives = 46/83 (55%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C C   YTG+ C+     C     C NGG C D+++   C C + G+ G RC+++++EC
Sbjct: 4077 VCQCRGLYTGQRCQLS-PYCKDEP-CKNGGTCFDSLDGAVCQCDS-GFRGERCQSDIDEC 4133

Query: 434  EEDRALCGHGVCYDTYGGFVCAC 502
              +  L G  +C +T+G + C C
Sbjct: 4134 SGNPCLHG-ALCENTHGSYHCNC 4155



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 32/88 (36%), Positives = 43/88 (48%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C C   Y G +CE  V+ CS +  CL GG CV     + C C    YTG RC+ +   C+
Sbjct: 4040 CKCSALYIGTHCEISVNPCS-SNPCLYGGTCVVDNGGFVCQCRGL-YTGQRCQLS-PYCK 4096

Query: 437  EDRALCGHGVCYDTYGGFVCACQPATPG 520
            ++    G G C+D+  G VC C     G
Sbjct: 4097 DEPCKNG-GTCFDSLDGAVCQCDSGFRG 4123



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 27/68 (39%), Positives = 37/68 (54%)
 Frame = +3

Query: 42   CEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNG 221
            C + A + CAS  C++G  C     G Y C C   Y GT+C  E+S++P C + PC   G
Sbjct: 4011 CFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHC--EISVNP-CSSNPCLYGG 4067

Query: 222  SCSVPPGG 245
            +C V  GG
Sbjct: 4068 TCVVDNGG 4075



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 22/54 (40%), Positives = 32/54 (59%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
            +C C  G+ G  C++D+DECSG   CL+G  C +   +Y C+C+   Y G  CE
Sbjct: 4114 VCQCDSGFRGERCQSDIDECSG-NPCLHGALCENTHGSYHCNCSHE-YRGRHCE 4165



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 21/53 (39%), Positives = 28/53 (52%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            C C + + G  C+ D  D C+   C HGA C E+  G Y C+C   Y G +CE
Sbjct: 4115 CQCDSGFRGERCQSDI-DECSGNPCLHGALC-ENTHGSYHCNCSHEYRGRHCE 4165


>AL359813-6|CAI23221.1|  288|Homo sapiens EGF-like-domain, multiple
           9 protein.
          Length = 288

 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
 Frame = +2

Query: 263 CPPGYTGRNCETDVDECSGAAA-CLNGGRCVDAVN---NYTCDCTATGYTGARCETNVNE 430
           C  G+ GR+CE     C  A + C NGG+C D      N+TC C   G+ GARCE NV++
Sbjct: 24  CDKGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRC-LVGFVGARCEVNVDD 82

Query: 431 CEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
           C   R       C D    F C C     G   T
Sbjct: 83  CLM-RPCANGATCLDGINRFSCLCPEGFAGRFCT 115



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  G+ G  CE +VD+C     C NG  C+D +N ++C C   G+ G  C  N+++C 
Sbjct: 65  CRCLVGFVGARCEVNVDDCL-MRPCANGATCLDGINRFSCLC-PEGFAGRFCTINLDDCA 122

Query: 437 EDRALCGHGV-CYDTYGGFVCACQPATPGST 526
                C  G  C D    F C C     G T
Sbjct: 123 S--RPCQRGARCRDRVHDFDCLCPSGYGGKT 151



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 27/75 (36%), Positives = 39/75 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  CEV+  D C    C +GA C+ DG   +SC CP G+ G +C   ++L
Sbjct: 63  FTCRCLVGFVGARCEVNVDD-CLMRPCANGATCL-DGINRFSCLCPEGFAGRFC--TINL 118

Query: 183 DPLCVAGPCRNNGSC 227
           D  C + PC+    C
Sbjct: 119 DD-CASRPCQRGARC 132



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   + G  C ++  D CAS  C+ GARC  D   D+ C CP GY G  CEL + +
Sbjct: 101 FSCLCPEGFAGRFCTINLDD-CASRPCQRGARC-RDRVHDFDCLCPSGYGGKTCELVLPV 158

Query: 183 --DPLCVAGPCRNNGSCSVPPGG 245
              P  V  P     +  VP  G
Sbjct: 159 PDPPTTVDTPLGPTSAVVVPATG 181



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 22/53 (41%), Positives = 32/53 (60%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C CP G+ GR C  ++D+C+ +  C  G RC D V+++ C C  +GY G  CE
Sbjct: 103 CLCPEGFAGRFCTINLDDCA-SRPCQRGARCRDRVHDFDCLC-PSGYGGKTCE 153



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRG---DYSCDCPPGYHGTYCELEVS 179
           C   + G +CE  AG PC  A + CR+G +C +D +G   +++C C  G+ G  CE+ V 
Sbjct: 24  CDKGFHGRDCERKAG-PCEQAGSPCRNGGQC-QDDQGFALNFTCRCLVGFVGARCEVNVD 81

Query: 180 LDPLCVAGPCRNNGSC 227
            D  C+  PC N  +C
Sbjct: 82  -D--CLMRPCANGATC 94



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
 Frame = +3

Query: 66  CASAACRHGARCV-EDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG-PCRNNGSCSVPP 239
           C    C    +C+   G     CD   G+HG  CE +    P   AG PCRN G C    
Sbjct: 2   CQHGTCHQPWQCICHSGWAGKFCD--KGFHGRDCERKAG--PCEQAGSPCRNGGQCQDDQ 57

Query: 240 G 242
           G
Sbjct: 58  G 58


>AL137007-1|CAC10575.2|  199|Homo sapiens novel EGF-like domain
           containing protein protein.
          Length = 199

 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 31/80 (38%), Positives = 43/80 (53%)
 Frame = +2

Query: 269 PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRA 448
           PG++G  CE +++ECS +  C N G CVD  N + C+C    Y G  CE +VN+C+    
Sbjct: 120 PGFSGSLCEIEINECS-SEPCKNNGTCVDLTNRFFCNCEPE-YHGPFCELDVNKCKISPC 177

Query: 449 LCGHGVCYDTYGGFVCACQP 508
           L      Y T  G+ C C P
Sbjct: 178 LDEENCVYRT-DGYNCLCAP 196



 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 31/88 (35%), Positives = 44/88 (50%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C   + G+NCE DV +C    +C + G C D VNN+       G++G+ CE  +NEC 
Sbjct: 82  CICREEFEGKNCEIDVKDCL-FLSCQDYGDCEDMVNNF-----RPGFSGSLCEIEINECS 135

Query: 437 EDRALCGHGVCYDTYGGFVCACQPATPG 520
            +     +G C D    F C C+P   G
Sbjct: 136 SEPCK-NNGTCVDLTNRFFCNCEPEYHG 162



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDG-RGDYSCDCPPGYHGTYCELEVSLD 185
           C CT+ +TG NC  +  + C S  C +G  C E    G + C CPP Y G +C    +L 
Sbjct: 1   CECTSGWTGQNCSEEINE-CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC 59

Query: 186 PLCVAGPCRNNGSC 227
            L +  PCRNN +C
Sbjct: 60  DL-LHNPCRNNSTC 72



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 23/67 (34%), Positives = 39/67 (58%)
 Frame = +3

Query: 27  YTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGP 206
           ++G+ CE++  + C+S  C++   CV D    + C+C P YHG +CEL+V+    C   P
Sbjct: 122 FSGSLCEIEINE-CSSEPCKNNGTCV-DLTNRFFCNCEPEYHGPFCELDVN---KCKISP 176

Query: 207 CRNNGSC 227
           C +  +C
Sbjct: 177 CLDEENC 183



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 26/73 (35%), Positives = 40/73 (54%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   + G NCE+D  D C   +C+    C ED   ++     PG+ G+ CE+E++   
Sbjct: 82  CICREEFEGKNCEIDVKD-CLFLSCQDYGDC-EDMVNNFR----PGFSGSLCEIEIN--- 132

Query: 189 LCVAGPCRNNGSC 227
            C + PC+NNG+C
Sbjct: 133 ECSSEPCKNNGTC 145



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAV--NNYTCDCTATGYTGARCETNVNE 430
           C C  G+TG+NC  +++EC  +  C+NGG C ++     + C C    YTG  C    N 
Sbjct: 1   CECTSGWTGQNCSEEINECD-SDPCMNGGLCHESTIPGQFVCLCPPL-YTGQFCHQRYNL 58

Query: 431 CE 436
           C+
Sbjct: 59  CD 60



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
 Frame = +2

Query: 374 CDCTATGYTGARCETNVNECEEDRALCGHGVCYDTY--GGFVCACQPATPG 520
           C+CT+ G+TG  C   +NEC+ D  + G G+C+++   G FVC C P   G
Sbjct: 1   CECTS-GWTGQNCSEEINECDSDPCMNG-GLCHESTIPGQFVCLCPPLYTG 49



 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 21/48 (43%), Positives = 26/48 (54%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT 400
           C C P Y G  CE DV++C   + CL+   CV   + Y C C A GYT
Sbjct: 154 CNCEPEYHGPFCELDVNKCK-ISPCLDEENCVYRTDGYNCLC-APGYT 199



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGA-AACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVN 427
           +C CPP YTG+ C    + C      C N   C+  V+ N  C C    + G  CE +V 
Sbjct: 40  VCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREE-FEGKNCEIDVK 98

Query: 428 EC 433
           +C
Sbjct: 99  DC 100



 Score = 37.5 bits (83), Expect = 0.039
 Identities = 18/47 (38%), Positives = 23/47 (48%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           C+C   Y G  CE+D  + C  + C     CV    G Y+C C PGY
Sbjct: 154 CNCEPEYHGPFCELDV-NKCKISPCLDEENCVYRTDG-YNCLCAPGY 198



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPC--ASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
           + C C   YTG  C     + C      CR+ + C+     +  C C   + G  CE++V
Sbjct: 39  FVCLCPPLYTGQFCH-QRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDV 97

Query: 177 SLDPLCVAGPCRNNGSC 227
             D  C+   C++ G C
Sbjct: 98  K-D--CLFLSCQDYGDC 111


>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
          Length = 2911

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
            C+C  G+ G   +  D+DECS G   C    +CV+   +Y C C+  G+TG     ++V+
Sbjct: 1392 CSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSE-GFTGDGFTCSDVD 1450

Query: 428  ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            EC E+  LC +G C +  G + C C+   TP S +  C+ +
Sbjct: 1451 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 1491



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C+C  GY     GR+C  D+DEC       +GG+C +    Y C C          +T  
Sbjct: 1265 CSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1323

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            +VNEC+ +  +C  G C +T G F+C CQ   +     TGC  V
Sbjct: 1324 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDV 1367



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G++  +    CE D+DECS G   C     C+++  +Y C+C A G+       C
Sbjct: 1832 CECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAA-GFKLSPNGAC 1889

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              + NEC E   +C HG+C D  G + C C
Sbjct: 1890 -VDRNECLEIPNVCSHGLCVDLQGSYQCIC 1918



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 35/89 (39%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+    TG NCE DVDEC G   C +G  C + +  Y C C       Y   +C 
Sbjct: 2596 CECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC- 2651

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             + NEC    A CG   CY+T G + CAC
Sbjct: 2652 VDENECSNPNA-CGSASCYNTLGSYKCAC 2679



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETNVNECEEDRALCGHGVCY 472
            D+DEC        GG C++   ++ C+C    Y     R   +++EC     +CG G CY
Sbjct: 1649 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1708

Query: 473  DTYGGFVCACQP 508
            +T G + C C P
Sbjct: 1709 NTLGNYTCICPP 1720



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  GY     G+NC  D +EC       + G C +   ++ C C       +    ++
Sbjct: 1998 CLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDI 2056

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            NEC+ED  +C  G C +T GGF C C P
Sbjct: 2057 NECDEDPNICLFGSCTNTPGGFQCLCPP 2084



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCET 418
            C CP GY    TG  C  D DECS    C NG  C + + ++ C+C      G    CE 
Sbjct: 2195 CECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCE- 2251

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            ++NEC ++  LC    C +T+G + C C
Sbjct: 2252 DINECAQNPLLCALR-CMNTFGSYECTC 2278



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C C  GY    +GRNC  D+DEC       + G C +   +Y+C C          ET  
Sbjct: 792  CNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE 850

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
            ++NECE +   C +G C +  G F C C P +   ST   C
Sbjct: 851  DINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLIC 889



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTGR---NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C CP GY      N   D +ECS   AC     C + + +Y C C + G++     + C 
Sbjct: 2636 CGCPQGYIQHYQWNQCVDENECSNPNAC-GSASCYNTLGSYKCACPS-GFSFDQFSSACH 2693

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +VNEC   +  C +G C +T GG++C C P
Sbjct: 2694 -DVNECSSSKNPCNYG-CSNTEGGYLCGCPP 2722



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
           DVDEC        GG C++ V ++ C C A      T  +CE +++EC     +C  G C
Sbjct: 275 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETGEC 333

Query: 470 YDTYGGFVCACQPATPGSTATGCRRVRQ 553
            +T G + C C P    ++  G R + Q
Sbjct: 334 SNTVGSYFCVC-PRGYVTSTDGSRCIDQ 360



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 34/90 (37%), Positives = 44/90 (48%), Gaps = 7/90 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCET 418
            C+CP GY     G+ C+ D+DEC           CV+ +  +TC C   G+T     C  
Sbjct: 2514 CSCPRGYVLQEDGKTCK-DLDECQTKQHNCQF-LCVNTLGGFTCKCPP-GFTQHHTACID 2570

Query: 419  NVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
            N NEC     LCG  G+C +T G F C CQ
Sbjct: 2571 N-NECGSQPLLCGGKGICQNTPGSFSCECQ 2599



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 36/103 (34%), Positives = 51/103 (49%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
            C C  G+T     R+C+ D+DECS    C++G  C +    + C C   GY    TG  C
Sbjct: 1473 CECEMGFTPASDSRSCQ-DIDECSFQNICVSG-TCNNLPGMFHCICD-DGYELDRTGGNC 1529

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
             T+++EC  D   C +G+C +T G + C C P      T  GC
Sbjct: 1530 -TDIDECA-DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC 1570



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRA 448
            TGR    D++EC         G+C + + ++ C C    A       C T+++EC     
Sbjct: 1065 TGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPD 1123

Query: 449  LCGHGVCYDTYGGFVCAC 502
            LCG G+C +T G F C C
Sbjct: 1124 LCGSGICVNTPGSFECEC 1141



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-- 415
            C C  GY       +NC  D+D C        GG CV+   ++ CDC          E  
Sbjct: 1139 CECFEGYESGFMMMKNC-MDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 1197

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP---ATP 517
             ++NEC     LC +G C +  G + C+C P   ATP
Sbjct: 1198 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 1234



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCE 415
           C C  G+     G+NC  D DEC+    CLNG  C++   ++ C C         G  C 
Sbjct: 599 CICNAGFELTTDGKNC-VDHDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYC- 655

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           T+V+EC+    +C +G C ++ G F C C P
Sbjct: 656 TDVDECQTP-GICMNGHCINSEGSFRCDCPP 685



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC  +    + G+C++   ++ C+C       YTG RC  + +EC      CG+G C
Sbjct: 2170 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNP-CGNGTC 2227

Query: 470  YDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +  G F C C           C  + +
Sbjct: 2228 TNVIGSFECNCNEGFEPGPMMNCEDINE 2255



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +2

Query: 248  HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCE 415
            H LC+   G T      D++EC+        G C +   +Y C+C + GY    +G  C 
Sbjct: 752  HGLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNS-GYEPDASGRNC- 807

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
             +++EC  +R LC +G+C +T G + C C P     T T
Sbjct: 808  IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTET 846



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
            C C  G+  +      D +EC       + G CVD   +Y C C   G+  ++ +T   +
Sbjct: 1875 CECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH-NGFKASQDQTMCMD 1933

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCACQP 508
            V+ECE  R  CG+G C +T G + C C P
Sbjct: 1934 VDECE--RHPCGNGTCKNTVGSYNCLCYP 1960



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCE 415
           C C  GY      +C  DVDEC+ +  C NG  CV+   +Y C C A G+    T   C 
Sbjct: 518 CECNMGYKQDANGDC-IDVDECT-SNPCTNGD-CVNTPGSYYCKCHA-GFQRTPTKQAC- 572

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC ++  LC +G C ++ G F C C
Sbjct: 573 IDIDECIQNGVLCKNGRCVNSDGSFQCIC 601



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCETN 421
            +C   PGYT      D+DEC         G+C++ + ++ C C   GYT    G  C  +
Sbjct: 2435 ICPHGPGYTTDG--RDIDECKVMPNLCTNGQCINTMGSFRCFC-KVGYTTDISGTSC-ID 2490

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            ++EC +    C + +C +T G + C+C
Sbjct: 2491 LDECSQSPKPCNY-ICKNTEGSYQCSC 2516



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECS-GAAACLNGGR-CVDAVNNYTCDCT---ATGYTGARC 412
            CTCP GY  R  +    D+DEC+ G   C + G  C + +  + C C    A    G  C
Sbjct: 2276 CTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 2335

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              + NEC     +C +G C +  G + C C       S+ T C   RQ
Sbjct: 2336 -VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2382



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  GYT    G +C  D+DECS +    N   C +   +Y C C   GY     G  C
Sbjct: 2473 CFCKVGYTTDISGTSC-IDLDECSQSPKPCNY-ICKNTEGSYQCSCPR-GYVLQEDGKTC 2529

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            + +++EC+  +  C   +C +T GGF C C P
Sbjct: 2530 K-DLDECQTKQHNCQF-LCVNTLGGFTCKCPP 2559



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
           C C  G+    T + C  D+DEC         GRCV++  ++ C C A G+     G  C
Sbjct: 557 CKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNSDGSFQCICNA-GFELTTDGKNC 614

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             + +EC     +C +G+C +  G F C C+P
Sbjct: 615 -VDHDECTTTN-MCLNGMCINEDGSFKCICKP 644



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARC 412
           C C PG+     GR C TDVDEC     C+N G C+++  ++ CDC    A G  G  C
Sbjct: 640 CICKPGFVLAPNGRYC-TDVDECQTPGICMN-GHCINSEGSFRCDCPPGLAVGMDGRVC 696



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 26/82 (31%), Positives = 34/82 (41%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C++    + C   +   C S  C +G  C +D      C C  GY GTYC       P
Sbjct: 130 CTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADD-----HCQCQKGYIGTYCG-----QP 178

Query: 189 LCVAGPCRNNGSCSVPPGGDTY 254
           +C  G C+N G C   P    Y
Sbjct: 179 VCENG-CQNGGRCIAQPCACVY 199



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
            Y C+C + Y    +G NC +D  +   +        C  +  G YSC CPPGY       
Sbjct: 790  YRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLC-RNTPGSYSCTCPPGYVFRTETE 847

Query: 159  YCE--LEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             CE   E   +P CV G CRNN GS  C   PG
Sbjct: 848  TCEDINECESNP-CVNGACRNNLGSFNCECSPG 879



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCE 415
            C C  GY    TG NC TD+DEC+    C+N G CV+    Y C+C        TG  C 
Sbjct: 1514 CICDDGYELDRTGGNC-TDIDECADPINCVN-GLCVNTPGRYECNCPPDFQLNPTGVGCV 1571

Query: 416  TN-VNEC 433
             N V  C
Sbjct: 1572 DNRVGNC 1578



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 26/71 (36%), Positives = 37/71 (52%), Gaps = 4/71 (5%)
 Frame = +2

Query: 302 VDECSGAA-ACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEEDRALCGHGVC 469
           +D C   A  CLNG RC+  V++Y C+C   GY       C  +V+EC  +   C +G C
Sbjct: 494 IDICKHHANLCLNG-RCIPTVSSYRCECN-MGYKQDANGDC-IDVDECTSNP--CTNGDC 548

Query: 470 YDTYGGFVCAC 502
            +T G + C C
Sbjct: 549 VNTPGSYYCKC 559



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
            +C CPPG      G  C  D +EC         GRCV+ + +Y C+C      G +  ++
Sbjct: 2319 MCICPPGMARRPDGEGC-VDENECRTKPGICENGRCVNIIGSYRCECN----EGFQSSSS 2373

Query: 422  VNECEEDR-ALC 454
              EC ++R  LC
Sbjct: 2374 GTECLDNRQGLC 2385



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
 Frame = +2

Query: 254  LCTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-TATGYTGAR--CE 415
            +C   PG+T         D+DEC         G C++ + ++ C+C T   Y      CE
Sbjct: 1789 ICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCE 1848

Query: 416  TNVNECEEDRALCGHGV-CYDTYGGFVCAC 502
             +++EC     LC     C ++ G + C C
Sbjct: 1849 -DIDECSNGDNLCQRNADCINSPGSYRCEC 1877



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
 Frame = +2

Query: 287  NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            N  T   EC        G  C     +  C        G  CE +VNECE    +C +G 
Sbjct: 911  NGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGR 969

Query: 467  CYDTYGGFVCAC-QPATPGSTATGCRRVRQD 556
            C ++ G F C C +  T   T   C  +R +
Sbjct: 970  CVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1000



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDC-TATGYTGARCETNV 424
            C C  G+     +T   DVDEC     C NG  C + V +Y C C      T      ++
Sbjct: 1916 CICHNGFKASQDQTMCMDVDECE-RHPCGNG-TCKNTVGSYNCLCYPGFELTHNNDCLDI 1973

Query: 425  NECEEDRA-LCGHGVCYDTYGGFVCAC 502
            +EC      +C +G C++  G F C C
Sbjct: 1974 DECSSFFGQVCRNGRCFNEIGSFKCLC 2000



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  G+      + C  DV+EC   +     G C +   ++ C C   GY+   G    
Sbjct: 1307 CLCYDGFMASMDMKTC-IDVNECDLNSNICMFGECENTKGSFICHCQL-GYSVKKGTTGC 1364

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
            T+V+ECE     C  H  C +  G F C+C+    G+
Sbjct: 1365 TDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN 1401



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 3/80 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV-- 424
           +CTC  G     C +  + +CS    C+NGG C D      C C   GY G  C   V  
Sbjct: 129 MCTCSSGQISSTCGSKSIQQCS--VRCMNGGTCADD----HCQC-QKGYIGTYCGQPVCE 181

Query: 425 NECEEDRALCGHGVCYDTYG 484
           N C ++   C    C   YG
Sbjct: 182 NGC-QNGGRCIAQPCACVYG 200



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 19/46 (41%), Positives = 23/46 (50%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQD 556
            +VNEC E   +C +G C +T G F C C P       TG R V  D
Sbjct: 2170 DVNECLESPGICSNGQCINTDGSFRCEC-PMGYNLDYTGVRCVDTD 2214



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY--- 161
            + C C   +    TG NCE D  +   +  C+HG + +    G Y C CP GY   Y   
Sbjct: 2594 FSCECQRGFSLDATGLNCE-DVDECDGNHRCQHGCQNI---LGGYRCGCPQGYIQHYQWN 2649

Query: 162  -C--ELEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             C  E E S    C +  C N  GS  C+ P G
Sbjct: 2650 QCVDENECSNPNACGSASCYNTLGSYKCACPSG 2682



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGY----HGTYC 164
            Y C C+  +TG+       D CA     C +G +C+ +  G Y C+C  G+        C
Sbjct: 1431 YRCACSEGFTGDGFTCSDVDECAENINLCENG-QCL-NVPGAYRCECEMGFTPASDSRSC 1488

Query: 165  E--LEVSLDPLCVAGPCRN 215
            +   E S   +CV+G C N
Sbjct: 1489 QDIDECSFQNICVSGTCNN 1507



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYC-ELEVSL--DPLC 194
           N C +D  D CA+  C       E+ RG Y C+C  GY     G  C +++  L    LC
Sbjct: 769 NECALDP-DICANGIC-------ENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLC 820

Query: 195 VAGPCRN---NGSCSVPPG 242
             G CRN   + SC+ PPG
Sbjct: 821 DNGLCRNTPGSYSCTCPPG 839



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCA-SAACRHGARCVEDGRGDYSCDCPPGYH--GTY 161
            ++C C   Y     G NC +D  +  A   +C  G  C ++  G + C CPPGY      
Sbjct: 1996 FKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGT-C-QNLEGSFRCICPPGYEVKSEN 2052

Query: 162  C-EL-EVSLDP-LCVAGPCRNNG---SCSVPPG 242
            C ++ E   DP +C+ G C N      C  PPG
Sbjct: 2053 CIDINECDEDPNICLFGSCTNTPGGFQCLCPPG 2085



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCS 230
            C +G +C+    G + C+CP GY+  Y  +  V  D   +  PC  NG+C+
Sbjct: 2181 CSNG-QCINTD-GSFRCECPMGYNLDYTGVRCVDTDECSIGNPC-GNGTCT 2228



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 8/88 (9%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            Y+C C   Y     G  C+ D  D C +        CV    G ++C CPPG+  H T C
Sbjct: 2512 YQCSCPRGYVLQEDGKTCK-DL-DECQTKQHNCQFLCVNT-LGGFTCKCPPGFTQHHTAC 2568

Query: 165  --ELEVSLDPLCVAGPCRNNGSCSVPPG 242
                E    PL     C   G C   PG
Sbjct: 2569 IDNNECGSQPLL----CGGKGICQNTPG 2592



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +++EC+    LC +G C +T G F C C+   T   + T C
Sbjct: 2448 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC 2488



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYH 152
            Y+C C + ++ +       D   C+S+   C +G    E G   Y C CPPGY+
Sbjct: 2675 YKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGG---YLCGCPPGYY 2725



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            +EC C   Y        NC    G       CR G  CV    G + CDCP G+  +   
Sbjct: 1137 FECECFEGYESGFMMMKNCMDIDGCERNPLLCR-GGTCVNT-EGSFQCDCPLGHELSPSR 1194

Query: 168  ------LEVSL-DPLCVAGPCRN---NGSCSVPPG 242
                   E SL D LC  G C N      CS  PG
Sbjct: 1195 EDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPG 1229



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
 Frame = +3

Query: 3    YECHCTARYTGN---NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
            +EC+C   +      NCE D  + CA        RC+    G Y C CP GY
Sbjct: 2234 FECNCNEGFEPGPMMNCE-DINE-CAQNPLLCALRCMNTF-GSYECTCPIGY 2282


>AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein.
          Length = 1321

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C  G+ G NCE D+D+C   + C NGG C+D VN + C C  + Y G+ CE +   C+
Sbjct: 1032 CSCDQGFAGENCEIDIDDCL-CSPCENGGTCIDEVNGFVCLCLPS-YGGSFCEKDTEGCD 1089

Query: 437  ED-RALCGHGVCY 472
                   GH  CY
Sbjct: 1090 RGWHKFQGH--CY 1100



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   + G NCE+D  D C  + C +G  C+++  G + C C P Y G++CE
Sbjct: 1030 YGCSCDQGFAGENCEIDI-DDCLCSPCENGGTCIDEVNG-FVCLCLPSYGGSFCE 1082



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 28/77 (36%), Positives = 35/77 (45%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY 472
            E   D C     CL+GG C      Y C C   G+ G  CE ++++C       G G C 
Sbjct: 1006 EVHSDPCENNP-CLHGGTCNANGTMYGCSCDQ-GFAGENCEIDIDDCLCSPCENG-GTCI 1062

Query: 473  DTYGGFVCACQPATPGS 523
            D   GFVC C P+  GS
Sbjct: 1063 DEVNGFVCLCLPSYGGS 1079



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 22/56 (39%), Positives = 30/56 (53%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            DPC +  C HG  C  +G   Y C C  G+ G  CE+++  D  C+  PC N G+C
Sbjct: 1010 DPCENNPCLHGGTCNANGTM-YGCSCDQGFAGENCEIDID-D--CLCSPCENGGTC 1061


>AC005254-1|AAC25581.1|  315|Homo sapiens PGCN_HUMAN, PARTIAL CDS
           protein.
          Length = 315

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C+C  G+ G NCE D+D+C   + C NGG C+D VN + C C  + Y G+ CE +   C+
Sbjct: 26  CSCDQGFAGENCEIDIDDCL-CSPCENGGTCIDEVNGFVCLCLPS-YGGSFCEKDTEGCD 83

Query: 437 ED-RALCGHGVCY 472
                  GH  CY
Sbjct: 84  RGWHKFQGH--CY 94



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           Y C C   + G NCE+D  D C  + C +G  C+++  G + C C P Y G++CE
Sbjct: 24  YGCSCDQGFAGENCEIDI-DDCLCSPCENGGTCIDEVNG-FVCLCLPSYGGSFCE 76



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 22/56 (39%), Positives = 30/56 (53%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           DPC +  C HG  C  +G   Y C C  G+ G  CE+++  D  C+  PC N G+C
Sbjct: 4   DPCENNPCLHGGTCNANGTM-YGCSCDQGFAGENCEIDID-D--CLCSPCENGGTC 55



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 25/65 (38%), Positives = 32/65 (49%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           CL+GG C      Y C C   G+ G  CE ++++C       G G C D   GFVC C P
Sbjct: 11  CLHGGTCNANGTMYGCSCDQ-GFAGENCEIDIDDCLCSPCENG-GTCIDEVNGFVCLCLP 68

Query: 509 ATPGS 523
           +  GS
Sbjct: 69  SYGGS 73


>AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein
            protein.
          Length = 1335

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
            C+C  G+ G NCE D+D+C   + C NGG C+D VN + C C  + Y G+ CE +   C+
Sbjct: 1046 CSCDQGFAGENCEIDIDDCL-CSPCENGGTCIDEVNGFVCLCLPS-YGGSFCEKDTEGCD 1103

Query: 437  ED-RALCGHGVCY 472
                   GH  CY
Sbjct: 1104 RGWHKFQGH--CY 1114



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
            Y C C   + G NCE+D  D C  + C +G  C+++  G + C C P Y G++CE
Sbjct: 1044 YGCSCDQGFAGENCEIDI-DDCLCSPCENGGTCIDEVNG-FVCLCLPSYGGSFCE 1096



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 28/77 (36%), Positives = 35/77 (45%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCY 472
            E   D C     CL+GG C      Y C C   G+ G  CE ++++C       G G C 
Sbjct: 1020 EVHSDPCENNP-CLHGGTCNANGTMYGCSCDQ-GFAGENCEIDIDDCLCSPCENG-GTCI 1076

Query: 473  DTYGGFVCACQPATPGS 523
            D   GFVC C P+  GS
Sbjct: 1077 DEVNGFVCLCLPSYGGS 1093



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 22/56 (39%), Positives = 30/56 (53%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            DPC +  C HG  C  +G   Y C C  G+ G  CE+++  D  C+  PC N G+C
Sbjct: 1024 DPCENNPCLHGGTCNANGTM-YGCSCDQGFAGENCEIDID-D--CLCSPCENGGTC 1075


>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
           contractural arachnodactyly) variant protein.
          Length = 1976

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 4/101 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET-DVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
           C+C  G+ G   +  D+DECS G   C    +CV+   +Y C C+  G+TG     ++V+
Sbjct: 457 CSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSE-GFTGDGFTCSDVD 515

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
           EC E+  LC +G C +  G + C C+   TP S +  C+ +
Sbjct: 516 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDI 556



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C+C  GY     GR+C  D+DEC       +GG+C +    Y C C          +T  
Sbjct: 330 CSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 388

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
           +VNEC+ +  +C  G C +T G F+C CQ   +     TGC  V
Sbjct: 389 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDV 432



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G++  +    CE D+DECS G   C     C+++  +Y C+C A G+       C
Sbjct: 897  CECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCECAA-GFKLSPNGAC 954

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              + NEC E   +C HG+C D  G + C C
Sbjct: 955  -VDRNECLEIPNVCSHGLCVDLQGSYQCIC 983



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 35/89 (39%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+    TG NCE DVDEC G   C +G  C + +  Y C C       Y   +C 
Sbjct: 1661 CECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC- 1716

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             + NEC    A CG   CY+T G + CAC
Sbjct: 1717 VDENECSNPNA-CGSASCYNTLGSYKCAC 1744



 Score = 60.5 bits (140), Expect = 5e-09
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETNVNECEEDRALCGHGVCY 472
           D+DEC        GG C++   ++ C+C    Y     R   +++EC     +CG G CY
Sbjct: 714 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 773

Query: 473 DTYGGFVCACQP 508
           +T G + C C P
Sbjct: 774 NTLGNYTCICPP 785



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCET 418
            C CP GY    TG  C  D DECS    C NG  C + + ++ C+C      G    CE 
Sbjct: 1260 CECPMGYNLDYTGVRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCE- 1316

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            ++NEC ++  LC    C +T+G + C C
Sbjct: 1317 DINECAQNPLLCAFR-CMNTFGSYECTC 1343



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  GY     G+NC  D +EC       + G C +   ++ C C       +    ++
Sbjct: 1063 CLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDI 1121

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            NEC+ED  +C  G C +T GGF C C P
Sbjct: 1122 NECDEDPNICLFGSCTNTPGGFQCLCPP 1149



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G+   +  
Sbjct: 162 CRCNSGFALDMEERNC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNC 220

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++ECE +  LC  G C +T G F C C
Sbjct: 221 MDIDECERNPLLCRGGTCVNTEGSFQCDC 249



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 10/97 (10%)
 Frame = +2

Query: 257 CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-- 415
           C C  GY       +NC  D+DEC        GG CV+   ++ CDC          E  
Sbjct: 204 CECFEGYESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 262

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP---ATP 517
            ++NEC     LC +G C +  G + C+C P   ATP
Sbjct: 263 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 299



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCET 418
            C+CP GY     G+ C+ D+DEC           CV+ +  +TC C   G+T     C  
Sbjct: 1579 CSCPRGYVLQEDGKTCK-DLDECQTKQHNCQF-LCVNTLGGFTCKCPP-GFTQHHTACID 1635

Query: 419  NVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
            N NEC    +LCG  G+C +T G F C CQ
Sbjct: 1636 N-NECGSQPSLCGAKGICQNTPGSFSCECQ 1664



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTGR---NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C CP GY      N   D +ECS   AC     C + + +Y C C + G++     + C 
Sbjct: 1701 CGCPQGYIQHYQWNQCVDENECSNPNAC-GSASCYNTLGSYKCACPS-GFSFDQFSSACH 1758

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +VNEC   +  C +G C +T GG++C C P
Sbjct: 1759 -DVNECSSSKNPCNYG-CSNTEGGYLCGCPP 1787



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRA 448
           TGR    D++EC         G+C + + ++ C C    A       C T+++EC     
Sbjct: 130 TGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPD 188

Query: 449 LCGHGVCYDTYGGFVCAC 502
           LCG G+C +T G F C C
Sbjct: 189 LCGSGICVNTPGSFECEC 206



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 36/103 (34%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARC 412
           C C  G+T     R+C+ D+DECS    C+ G  C +    + C C   GY    TG  C
Sbjct: 538 CECEMGFTPASDSRSCQ-DIDECSFQNICVFG-TCNNLPGMFHCICD-DGYELDRTGGNC 594

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
            T+++EC  D   C +G+C +T G + C C P      T  GC
Sbjct: 595 -TDIDECA-DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGC 635



 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC  +    + G+C++   ++ C+C       YTG RC  + +EC      CG+G C
Sbjct: 1235 DVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNP-CGNGTC 1292

Query: 470  YDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +  G F C C           C  + +
Sbjct: 1293 TNVIGSFECNCNEGFEPGPMMNCEDINE 1320



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
 Frame = +2

Query: 257  CTCPPGY--TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
            C C  G+  +      D +EC       + G CVD   +Y C C   G+  ++ +T   +
Sbjct: 940  CECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH-NGFKASQDQTMCMD 998

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCACQP 508
            V+ECE  R  CG+G C +T G + C C P
Sbjct: 999  VDECE--RHPCGNGTCKNTVGSYNCLCYP 1025



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCETN 421
            +C   PGYT      D+DEC         G+C++ + ++ C C   GYT    G  C  +
Sbjct: 1500 ICPHGPGYTTDG--RDIDECKVMPNLCTNGQCINTMGSFRCFC-KVGYTTDISGTSC-ID 1555

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC 502
            ++EC +    C + +C +T G + C+C
Sbjct: 1556 LDECSQSPKPCNY-ICKNTEGSYQCSC 1581



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECS-GAAACLNGGR-CVDAVNNYTCDCT---ATGYTGARC 412
            CTCP GY  R  +    D+DEC+ G   C + G  C + +  + C C    A    G  C
Sbjct: 1341 CTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 1400

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              + NEC     +C +G C +  G + C C       S+ T C   RQ
Sbjct: 1401 -VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQ 1447



 Score = 48.4 bits (110), Expect = 2e-05
 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  GYT    G +C  D+DECS +    N   C +   +Y C C   GY     G  C
Sbjct: 1538 CFCKVGYTTDISGTSC-IDLDECSQSPKPCNY-ICKNTEGSYQCSCPR-GYVLQEDGKTC 1594

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            + +++EC+  +  C   +C +T GGF C C P
Sbjct: 1595 K-DLDECQTKQHNCQF-LCVNTLGGFTCKCPP 1624



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCE 415
           C C  GY    TG NC TD+DEC+    C+N G CV+    Y C+C        TG  C 
Sbjct: 579 CICDDGYELDRTGGNC-TDIDECADPINCVN-GLCVNTPGRYECNCPPDFQLNPTGVGCV 636

Query: 416 TN-VNEC 433
            N V  C
Sbjct: 637 DNRVGNC 643



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
            +C CPPG      G  C  D +EC         GRCV+ + +Y C+C      G +  ++
Sbjct: 1384 MCICPPGMARRPDGEGC-VDENECRTKPGICENGRCVNIIGSYRCECN----EGFQSSSS 1438

Query: 422  VNECEEDR-ALC 454
              EC ++R  LC
Sbjct: 1439 GTECLDNRQGLC 1450



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
 Frame = +2

Query: 254  LCTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC-TATGYTGAR--CE 415
            +C   PG+T         D+DEC         G C++ + ++ C+C T   Y      CE
Sbjct: 854  ICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCE 913

Query: 416  TNVNECEEDRALCGHGV-CYDTYGGFVCAC 502
             +++EC     LC     C ++ G + C C
Sbjct: 914  -DIDECSNGDNLCQRNADCINSPGSYRCEC 942



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDC-TATGYTGARCETNV 424
            C C  G+     +T   DVDEC     C NG  C + V +Y C C      T      ++
Sbjct: 981  CICHNGFKASQDQTMCMDVDECE-RHPCGNG-TCKNTVGSYNCLCYPGFELTHNNDCLDI 1038

Query: 425  NECEEDRA-LCGHGVCYDTYGGFVCAC 502
            +EC      +C +G C++  G F C C
Sbjct: 1039 DECSSFFGQVCRNGRCFNEIGSFKCLC 1065



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
 Frame = +2

Query: 257 CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+      + C  DV+EC   +     G C +   ++ C C   GY+   G    
Sbjct: 372 CLCYDGFMASMDMKTC-IDVNECDLNSNICMFGECENTKGSFICHCQL-GYSVKKGTTGC 429

Query: 416 TNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
           T+V+ECE     C  H  C +  G F C+C+    G+
Sbjct: 430 TDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN 466



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
 Frame = +2

Query: 401 GARCETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQD 556
           G  CE +VNECE    +C +G C ++ G F C C +  T   T   C  +R +
Sbjct: 14  GVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 65



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 19/46 (41%), Positives = 23/46 (50%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQD 556
            +VNEC E   +C +G C +T G F C C P       TG R V  D
Sbjct: 1235 DVNECLESPGICSNGQCINTDGSFRCEC-PMGYNLDYTGVRCVDTD 1279



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTY--- 161
            + C C   +    TG NCE D  +   +  C+HG + +    G Y C CP GY   Y   
Sbjct: 1659 FSCECQRGFSLDATGLNCE-DVDECDGNHRCQHGCQNI---LGGYRCGCPQGYIQHYQWN 1714

Query: 162  -C--ELEVSLDPLCVAGPCRNN-GS--CSVPPG 242
             C  E E S    C +  C N  GS  C+ P G
Sbjct: 1715 QCVDENECSNPNACGSASCYNTLGSYKCACPSG 1747



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCA-SAACRHGARCVEDGRGDYSCDCPPGYH--GTY 161
            ++C C   Y     G NC +D  +  A   +C  G  C ++  G + C CPPGY      
Sbjct: 1061 FKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGT-C-QNLEGSFRCICPPGYEVKSEN 1117

Query: 162  C-EL-EVSLDP-LCVAGPCRNNG---SCSVPPG 242
            C ++ E   DP +C+ G C N      C  PPG
Sbjct: 1118 CIDINECDEDPNICLFGSCTNTPGGFQCLCPPG 1150



 Score = 35.5 bits (78), Expect = 0.16
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGY----HGTYC 164
           Y C C+  +TG+       D CA     C +G +C+ +  G Y C+C  G+        C
Sbjct: 496 YRCACSEGFTGDGFTCSDVDECAENINLCENG-QCL-NVPGAYRCECEMGFTPASDSRSC 553

Query: 165 E--LEVSLDPLCVAGPCRN 215
           +   E S   +CV G C N
Sbjct: 554 QDIDECSFQNICVFGTCNN 572



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCS 230
            C +G +C+    G + C+CP GY+  Y  +  V  D   +  PC  NG+C+
Sbjct: 1246 CSNG-QCINTD-GSFRCECPMGYNLDYTGVRCVDTDECSIGNPC-GNGTCT 1293



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 3/43 (6%)
 Frame = +2

Query: 263 CPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           CP G     G  CE DV+EC         GRCV++  ++ C+C
Sbjct: 5   CPRGLARIKGVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCEC 46



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +++EC+    LC +G C +T G F C C+   T   + T C
Sbjct: 1513 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC 1553



 Score = 31.9 bits (69), Expect = 2.0
 Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 11/87 (12%)
 Frame = +3

Query: 3    YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC 164
            Y+C C   Y     G  C+ D  D C +        CV    G ++C CPPG+  H T C
Sbjct: 1577 YQCSCPRGYVLQEDGKTCK-DL-DECQTKQHNCQFLCVNT-LGGFTCKCPPGFTQHHTAC 1633

Query: 165  --ELEVSLDP-LCVA-GPCRNN-GSCS 230
                E    P LC A G C+N  GS S
Sbjct: 1634 IDNNECGSQPSLCGAKGICQNTPGSFS 1660



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYH 152
            Y+C C + ++ +       D   C+S+   C +G    E G   Y C CPPGY+
Sbjct: 1740 YKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGG---YLCGCPPGYY 1790


>D83017-1|BAA11680.1|  810|Homo sapiens nel-related protein protein.
          Length = 810

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA-------TGYTGARC 412
           C CP G+TG +CE D+DECS G   C N  RCV+    Y C+C +          +G  C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594

Query: 413 ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATP 517
             +++EC      C     C +  GGF C C P+ P
Sbjct: 595 -IDIDECALRTHTCWNDSACINLAGGFDCLC-PSGP 628



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           CTC PGY G    C    +E      C  GG CV A N   C    +G+TG+ CE +++E
Sbjct: 502 CTCKPGYVGNGTICRAFCEE-----GCRYGGTCV-APNKCVC---PSGFTGSHCEKDIDE 552

Query: 431 CEEDRALC-GHGVCYDTYGGFVCACQ 505
           C E    C  H  C +  G + C C+
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECR 578



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH--GTYC--- 164
           +C C + +TG++CE D  D C+     C + +RCV +  G Y C+C  G+H  GTY    
Sbjct: 534 KCVCPSGFTGSHCEKDI-DECSEGIIECHNHSRCV-NLPGWYHCECRSGFHDDGTYSLSG 591

Query: 165 ELEVSLDPLCV-AGPCRNNGSCSVPPGG 245
           E  + +D   +    C N+ +C    GG
Sbjct: 592 ESCIDIDECALRTHTCWNDSACINLAGG 619



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRN-----CETDVDECSGAAA-CLNGGRCVDAVNNYTCDCTATGYTGA---R 409
           C C  GY         CE D+DEC+     C     CV+    Y CDC   GY       
Sbjct: 416 CECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLYRCDCVP-GYIRVDDFS 473

Query: 410 CETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCR 541
           C T  +EC   +  C  + +C +T  G  C C+P   G+  T CR
Sbjct: 474 C-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN-GTICR 516



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y GN     A        CR+G  CV   +    C CP G+ G++CE ++  
Sbjct: 500 HSCTCKPGYVGNGTICRA---FCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID- 551

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C N+  C   PG
Sbjct: 552 --ECSEGIIECHNHSRCVNLPG 571


>BC096102-1|AAH96102.1|  810|Homo sapiens NEL-like 1 (chicken)
           protein.
          Length = 810

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA-------TGYTGARC 412
           C CP G+TG +CE D+DECS G   C N  RCV+    Y C+C +          +G  C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594

Query: 413 ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATP 517
             +++EC      C     C +  GGF C C P+ P
Sbjct: 595 -IDIDECALRTHTCWNDSACINLAGGFDCLC-PSGP 628



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           CTC PGY G    C    +E      C  GG CV A N   C    +G+TG+ CE +++E
Sbjct: 502 CTCKPGYVGNGTICRAFCEE-----GCRYGGTCV-APNKCVC---PSGFTGSHCEKDIDE 552

Query: 431 CEEDRALC-GHGVCYDTYGGFVCACQ 505
           C E    C  H  C +  G + C C+
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECR 578



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH--GTYC--- 164
           +C C + +TG++CE D  D C+     C + +RCV +  G Y C+C  G+H  GTY    
Sbjct: 534 KCVCPSGFTGSHCEKDI-DECSEGIIECHNHSRCV-NLPGWYHCECRSGFHDDGTYSLSG 591

Query: 165 ELEVSLDPLCV-AGPCRNNGSCSVPPGG 245
           E  + +D   +    C N+ +C    GG
Sbjct: 592 ESCIDIDECALRTHTCWNDSACINLAGG 619



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRN-----CETDVDECSGAAA-CLNGGRCVDAVNNYTCDCTATGYTGA---R 409
           C C  GY         CE D+DEC+     C     CV+    Y CDC   GY       
Sbjct: 416 CECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLYRCDCVP-GYIRVDDFS 473

Query: 410 CETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCR 541
           C T  +EC   +  C  + +C +T  G  C C+P   G+  T CR
Sbjct: 474 C-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN-GTICR 516



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y GN     A        CR+G  CV   +    C CP G+ G++CE ++  
Sbjct: 500 HSCTCKPGYVGNGTICRA---FCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID- 551

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C N+  C   PG
Sbjct: 552 --ECSEGIIECHNHSRCVNLPG 571


>BC096101-1|AAH96101.1|  810|Homo sapiens NEL-like 1 (chicken)
           protein.
          Length = 810

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA-------TGYTGARC 412
           C CP G+TG +CE D+DECS G   C N  RCV+    Y C+C +          +G  C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594

Query: 413 ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATP 517
             +++EC      C     C +  GGF C C P+ P
Sbjct: 595 -IDIDECALRTHTCWNDSACINLAGGFDCLC-PSGP 628



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           CTC PGY G    C    +E      C  GG CV A N   C    +G+TG+ CE +++E
Sbjct: 502 CTCKPGYVGNGTICRAFCEE-----GCRYGGTCV-APNKCVC---PSGFTGSHCEKDIDE 552

Query: 431 CEEDRALC-GHGVCYDTYGGFVCACQ 505
           C E    C  H  C +  G + C C+
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECR 578



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH--GTYC--- 164
           +C C + +TG++CE D  D C+     C + +RCV +  G Y C+C  G+H  GTY    
Sbjct: 534 KCVCPSGFTGSHCEKDI-DECSEGIIECHNHSRCV-NLPGWYHCECRSGFHDDGTYSLSG 591

Query: 165 ELEVSLDPLCV-AGPCRNNGSCSVPPGG 245
           E  + +D   +    C N+ +C    GG
Sbjct: 592 ESCIDIDECALRTHTCWNDSACINLAGG 619



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRN-----CETDVDECSGAAA-CLNGGRCVDAVNNYTCDCTATGYTGA---R 409
           C C  GY         CE D+DEC+     C     CV+    Y CDC   GY       
Sbjct: 416 CECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLYRCDCVP-GYIRVDDFS 473

Query: 410 CETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCR 541
           C T  +EC   +  C  + +C +T  G  C C+P   G+  T CR
Sbjct: 474 C-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN-GTICR 516



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y GN     A        CR+G  CV   +    C CP G+ G++CE ++  
Sbjct: 500 HSCTCKPGYVGNGTICRA---FCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID- 551

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C N+  C   PG
Sbjct: 552 --ECSEGIIECHNHSRCVNLPG 571


>BC069674-1|AAH69674.1|  810|Homo sapiens nel-like 1, precursor
           protein.
          Length = 810

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 35/96 (36%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA-------TGYTGARC 412
           C CP G+TG +CE D+DECS G   C N  RCV+    Y C+C +          +G  C
Sbjct: 535 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESC 594

Query: 413 ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATP 517
             +++EC      C     C +  GGF C C P+ P
Sbjct: 595 -IDIDECALRTHTCWNDSACINLAGGFDCLC-PSGP 628



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           CTC PGY G    C    +E      C  GG CV A N   C    +G+TG+ CE +++E
Sbjct: 502 CTCKPGYVGNGTICRAFCEE-----GCRYGGTCV-APNKCVC---PSGFTGSHCEKDIDE 552

Query: 431 CEEDRALC-GHGVCYDTYGGFVCACQ 505
           C E    C  H  C +  G + C C+
Sbjct: 553 CSEGIIECHNHSRCVNLPGWYHCECR 578



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGYH--GTYC--- 164
           +C C + +TG++CE D  D C+     C + +RCV +  G Y C+C  G+H  GTY    
Sbjct: 534 KCVCPSGFTGSHCEKDI-DECSEGIIECHNHSRCV-NLPGWYHCECRSGFHDDGTYSLSG 591

Query: 165 ELEVSLDPLCV-AGPCRNNGSCSVPPGG 245
           E  + +D   +    C N+ +C    GG
Sbjct: 592 ESCIDIDECALRTHTCWNDSACINLAGG 619



 Score = 43.2 bits (97), Expect = 8e-04
 Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 10/105 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRN-----CETDVDECSGAAA-CLNGGRCVDAVNNYTCDCTATGYTGA---R 409
           C C  GY         CE D+DEC+     C     CV+    Y CDC   GY       
Sbjct: 416 CECKSGYISVQGDSAYCE-DIDECAAKMHYCHANTVCVNLPGLYRCDCVP-GYIRVDDFS 473

Query: 410 CETNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGSTATGCR 541
           C T  +EC   +  C  + +C +T  G  C C+P   G+  T CR
Sbjct: 474 C-TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGN-GTICR 516



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y GN     A        CR+G  CV   +    C CP G+ G++CE ++  
Sbjct: 500 HSCTCKPGYVGNGTICRA---FCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID- 551

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C N+  C   PG
Sbjct: 552 --ECSEGIIECHNHSRCVNLPG 571


>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 3 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 2 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
            precursor transcript variant 1 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AK131282-1|BAD18457.1|  872|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16233 fis, clone FEBRA2028256, moderately
           similar to FIBRILLIN 2 PRECURSOR. ).
          Length = 872

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
           LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 295 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 353

Query: 404 ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
             C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 354 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 403



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 37/103 (35%), Positives = 48/103 (46%), Gaps = 6/103 (5%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARCETN 421
           C CPPG+T  +    DV+EC G   C +G  C + +  Y C C   G+T     A+C  +
Sbjct: 576 CRCPPGFTQHHQACFDVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC-VD 631

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
            NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 632 ENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 674



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 215 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 271

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +++EC  +  LC    C++T G ++C C
Sbjct: 272 DIDECSLNPLLCAFR-CHNTEGSYLCTC 298



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C        +   +
Sbjct: 534 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQ-FLCVNTVGAFTCRCPPGFTQHHQACFD 591

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           VNEC+     C HG C +  GG+ C+C
Sbjct: 592 VNECDGPHR-CQHG-CQNQLGGYRCSC 616



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
           DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 247

Query: 470 YDTYGGFVCAC 502
            +  GGF CAC
Sbjct: 248 TNVIGGFECAC 258



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
           LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 456 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 512

Query: 425 NECEEDRALCGHGVCYDTYGGFVCAC 502
           +EC +    C   +C +T G F+C+C
Sbjct: 513 DECSQVPKPCTF-LCKNTKGSFLCSC 537



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 461 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 509



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257 CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
           C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 614 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 671

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           + +V+EC   R  C +  C +T GGF+C C
Sbjct: 672 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 699



 Score = 39.5 bits (88), Expect = 0.010
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
 Frame = +2

Query: 320 AAACLNG-GRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVC 496
           AAA + G GR  +   N        G   +R   +VNEC E+  +C +GVC +T G F C
Sbjct: 158 AAAAVRGLGRAGETPANCVSRRAVPGPDDSR--EDVNECAENPGVCTNGVCVNTDGSFRC 215

Query: 497 AC 502
            C
Sbjct: 216 EC 217



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
           C C  GYT     T   D+DECS          C +   ++ C C   GY     G  C+
Sbjct: 494 CHCQAGYTPDATATTCLDMDECSQVPKPCTF-LCKNTKGSFLCSCPR-GYLLEEDGRTCK 551

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC   +  C   +C +T G F C C P
Sbjct: 552 -DLDECTSRQHNCQF-LCVNTVGAFTCRCPP 580



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 11/93 (11%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEV-DAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
           + C C   +T ++    D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 574 FTCRCPPGFTQHHQACFDVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 630

Query: 165 -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
            E E +L  P C +  CRN  G   C  P G D
Sbjct: 631 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 663



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81  CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
           C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 201 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 253


>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
          Length = 1365

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C+C PG+      R+C TD+DEC       +GG+C +    Y C C          +T  
Sbjct: 1221 CSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 1279

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTA-TGCRRVRQ 553
            +VNEC+ +  +C  G C +T G F+C C     G    TGC  + +
Sbjct: 1280 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINE 1325



 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G+      RNC TD+DEC  +      G+CV+   ++ C C     +G+   +  
Sbjct: 1053 CRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 1111

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +++EC+ D  LC  GVC++T G + C C P
Sbjct: 1112 MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142



 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+     G+NCE D+DECS    CLNG  C++   ++ C C         G  C+
Sbjct: 555 CVCNAGFHVTRDGKNCE-DMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYCK 612

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            ++NECE    +C +G C +T G + C C P
Sbjct: 613 -DINECETP-GICMNGRCVNTDGSYRCECFP 641



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  GY       +NC  D+DEC        GG C +   +Y C+C             
Sbjct: 1095 CKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 1153

Query: 419  -NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             ++NECE    LC +G C +  G + CAC P
Sbjct: 1154 IDINECELSAHLCPNGRCVNLIGKYQCACNP 1184



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCET 418
           C C  GY      T   D+DEC       N GRC++   ++ C C A  +    G  CE 
Sbjct: 513 CQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE- 571

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           +++EC   R +C +G+C +  G F C C+P
Sbjct: 572 DMDEC-SIRNMCLNGMCINEDGSFKCICKP 600



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETN 421
           LC+  PG T     +D++EC+        G C +    Y C C + GY    TG  C  +
Sbjct: 710 LCSSGPGMTSAG--SDINECALDPDICPNGICENLRGTYKCICNS-GYEVDSTGKNC-VD 765

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           +NEC  +  LC +G C +T G FVC C
Sbjct: 766 INECVLNSLLCDNGQCRNTPGSFVCTC 792



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
            C C  G+      + C  DV+EC      CL+G  C +   ++ C C   GY+G + +T 
Sbjct: 1263 CLCYDGFMASEDMKTC-VDVNECDLNPNICLSG-TCENTKGSFICHCDM-GYSGKKGKTG 1319

Query: 419  --NVNECEEDRALCG-HGVCYDTYGGFVCACQPATPG 520
              ++NECE     CG H VC +T G F C+C P   G
Sbjct: 1320 CTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCETNVNECEEDRALCGHGVC 469
           DVDEC        GG C++ V ++ C C A         +CE +++EC     +C  G C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGEC 304

Query: 470 YDTYGGFVCACQPATPGS-TATGCRRVR 550
            +T   + C C P    S   T C  VR
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCIDVR 332



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
 Frame = +2

Query: 257 CTCPPGYTG--RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---N 421
           C C  G+    R    DVDEC        GG C++   +YTC C A GY      T   +
Sbjct: 474 CECNKGFQLDLRGECIDVDECEKNPCA--GGECINNQGSYTCQCRA-GYQSTLTRTECRD 530

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCAC 502
           ++EC ++  +C +G C +T G F C C
Sbjct: 531 IDECLQNGRICNNGRCINTDGSFHCVC 557



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C C  GY    TG+NC  D++EC   +   + G+C +   ++ C C          +T  
Sbjct: 748  CICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCE 806

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
            +++ECE     C +GVC ++ G F+C C   +T   T T C
Sbjct: 807  DIDECESSP--CINGVCKNSPGSFICECSSESTLDPTKTIC 845



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257  CTCPPGYT-GRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---T 418
            C CPPG+    N     D++EC  +A     GRCV+ +  Y C C   GY          
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCV 1196

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC      C    C ++ G + C+CQP
Sbjct: 1197 DIDECSIMNGGC-ETFCTNSEGSYECSCQP 1225



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
 Frame = +2

Query: 254  LCTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGA 406
            LC   PG+       G+    D++EC    +    G+C + + ++ C C  +G+   +  
Sbjct: 1007 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD-SGFALDSEE 1065

Query: 407  RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            R  T+++EC     LCG G C +T G F C C
Sbjct: 1066 RNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 30/80 (37%), Positives = 38/80 (47%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECE 436
           C C  GY G +C   V E    + CLNGGRCV A N   C CT  G+TG +CE +     
Sbjct: 134 CLCQKGYIGTHCGQPVCE----SGCLNGGRCV-APNR--CACT-YGFTGPQCERDY-RTG 184

Query: 437 EDRALCGHGVCYDTYGGFVC 496
               +  + +C     G VC
Sbjct: 185 PCFTVISNQMCQGQLSGIVC 204



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
           C CP G+      + CE D+DECS       GG C + V++Y C C    YT   G RC
Sbjct: 271 CKCPAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRC 328



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
 Frame = +2

Query: 305 DECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-NVNECEEDRALCGHGVCYDTY 481
           D C         GRC+    +  C+C        R E  +V+ECE++   C  G C +  
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNP--CAGGECINNQ 508

Query: 482 GGFVCACQPATPGS-TATGCRRV 547
           G + C C+     + T T CR +
Sbjct: 509 GSYTCQCRAGYQSTLTRTECRDI 531



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 24/83 (28%), Positives = 37/83 (44%)
 Frame = +2

Query: 287  NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            N  T   +C  +     G  C     +  C    +   G +CE +++ECE    +C +G+
Sbjct: 867  NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGL 925

Query: 467  CYDTYGGFVCACQPATPGSTATG 535
            C +T G F C C P+     ATG
Sbjct: 926  CVNTRGSFKCQC-PSGMTLDATG 947



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 20/60 (33%), Positives = 25/60 (41%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   Y G +C    G P   + C +G RCV   R    C C  G+ G  CE +    P
Sbjct: 134 CLCQKGYIGTHC----GQPVCESGCLNGGRCVAPNR----CACTYGFTGPQCERDYRTGP 185



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
 Frame = +3

Query: 36  NNCEVDAGD---PCASAACRH-GARCVEDGR-GDYSCDCPPGYHGTYCELEVSLDPLCVA 200
           N C   +G     C S + +H   RC+  G   D  C C  GY GT+C       P+C +
Sbjct: 98  NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCG-----QPVCES 152

Query: 201 GPCRNNGSCSVP 236
           G C N G C  P
Sbjct: 153 G-CLNGGRCVAP 163



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
 Frame = +2

Query: 254 LCTCPPGYTGRNC-ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           +CTCP G    +C    +  C+    C+NGG C D      C C   GY G  C   V E
Sbjct: 99  MCTCPSGQIAPSCGSRSIQHCN--IRCMNGGSCSDD----HCLC-QKGYIGTHCGQPVCE 151

Query: 431 --CEEDRALCGHGVCYDTYG 484
             C           C  TYG
Sbjct: 152 SGCLNGGRCVAPNRCACTYG 171



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 1/57 (1%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV-SLDPLCVAGPCRNNGSC 227
           D C    C  G  C+ + +G Y+C C  GY  T    E   +D     G   NNG C
Sbjct: 492 DECEKNPCA-GGECINN-QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRC 546



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
            ++C C + +  ++ E +  D   C  +   C  G +CV    GD+ C C  GY   +  +
Sbjct: 1051 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTP-GDFECKCDEGYESGFMMM 1108

Query: 171  -------EVSLDP-LCVAGPCRN-NGS--CSVPPG 242
                   E   DP LC  G C N  GS  C  PPG
Sbjct: 1109 KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 1143



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGD--PCASAACRHGARCV-EDGRGDYSCDCPPGYHG 155
            CHC   Y+G   +    D   C   A   G   V  +  G + C C PG+ G
Sbjct: 1305 CHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIG 1356



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 36   NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
            N CE+ A        C +G RCV +  G Y C C PGYH T
Sbjct: 1157 NECELSAH------LCPNG-RCV-NLIGKYQCACNPGYHST 1189


>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCWGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCWGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 29/83 (34%), Positives = 33/83 (39%), Gaps = 12/83 (14%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----G 155
            +EC C   Y        NC +D  +         G  C     G Y C CPPG+     G
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDVDECARDPLLCWGGTCTNTD-GSYKCQCPPGHELTAKG 1108

Query: 156  TYCE--LEVSL-DPLCVAGPCRN 215
            T CE   E SL D LC  G C N
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVN 1131



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
          Length = 2809

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2189 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2248 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297



 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1746 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1803

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1804 -VGRNECREIPNVCSHGDCMDTEGSYMCLC 1832



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1053 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1110

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1111 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1140



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC    ++CG G C
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSSICGPGTC 1621

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1622 YNTLGNYTCVC 1632



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2428 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2484

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2485 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2531



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1011 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1069

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1070 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1179 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1236

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1237 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1281



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1306 CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1363

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECE 1390



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2511 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2566

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2567 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2611



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 472 CQCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 530

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 531 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 559



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2109 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2165

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2166 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2192



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 979  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1039 CGQGTCVNTPGSFECECFP 1057



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1096 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1153

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1154 VDINECRVQNGGCDVH--CINTEGSYRCSC 1181



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1912 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1970

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPP 1998



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2141

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2142 TNVIGGFECAC 2152



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1387 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1443

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1444 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1484



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 707 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 795



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2350 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2406

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2407 DECSQVPKPCTF-LCKNTKGSFLCSC 2431



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 656 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 714

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 715 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 753



 Score = 46.8 bits (106), Expect = 6e-05
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  ++    G C + + NYTC C A
Sbjct: 1588 CECPPGYHLSEHTRICE-DIDECSTHSSICGPGTCYNTLGNYTCVCPA 1634



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 514 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 570

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 571 MDIDECQTP-GICVNGHCTNTEGSFRCQC 598



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 705 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 760

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 761 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 794



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1221 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1277

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1314



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1789 CKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1846

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1847 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1874



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 419 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCQC 474

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 475 YPGFQATP 482



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2355 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2551 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2608

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2609 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2636



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 431 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCQCYPGFQATPTRQACV 488

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 489 DVDECIVSGGLCHLGRC 505



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 101 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 149

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 150 ICDRG-CHNGGRCIGP 164



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1779

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECRE 1811



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 238 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 291

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 292 A----GACFSVLFGGRCA 305



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 833  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 891

Query: 488  FVCAC 502
            F C C
Sbjct: 892  FRCEC 896



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 512 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 568

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 569 YCMDIDECQTPGICVNGHCTN 589



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1051 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1106

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1107 KGTACEDIDECSLSDGLCPHGQCVN 1131



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 135 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 186



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1884

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1915



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1563 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1592



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1924 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1979

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1980 CLFGTCTNSPGSFQCLCPPG 1999



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2512 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2567

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2568 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2600



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 135 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 179



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 863 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 896



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 684 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 735

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 736 DNGWCQNSPGSYSCSCPPG 754



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1039 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1096

Query: 228  SVPPG 242
              PPG
Sbjct: 1097 QCPPG 1101



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2429 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2485

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2486 NDECSAQP----GPCGAHGHCHNTPG 2507



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 241 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 274



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2095 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2147



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1576 GGDCVNTF-GSFQCECPPGYH 1595



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1715 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1768

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1769 SRESPCQQNADCINIPG 1785


>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
          Length = 2816

 Score = 64.9 bits (151), Expect = 2e-10
 Identities = 42/111 (37%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECS-GAAAC-LNGGRCVDAVNNYTCDCTA----TGYTG 403
            LCTCP GYT    G  C  DVDEC+ G   C   G  C + +  + C C         +G
Sbjct: 2196 LCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2254

Query: 404  ARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRVRQ 553
              C T+ NEC     LC +G C +T G F C C     P  T T C  +RQ
Sbjct: 2255 EGC-TDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2304



 Score = 64.1 bits (149), Expect = 4e-10
 Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C CP G+   +    CE DVDEC S  + C     C++   +Y C CT  GY    G  C
Sbjct: 1753 CECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTR-GYKLSPGGAC 1810

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                NEC E   +C HG C DT G ++C C
Sbjct: 1811 -VGQNECREIPNVCSHGDCMDTEGSYMCLC 1839



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257  CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GAR 409
            C C PGY       +NC  DVDEC+       GG C +   +Y C C   G+     G  
Sbjct: 1060 CECFPGYESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPP-GHELTAKGTA 1117

Query: 410  CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            CE +++EC     LC HG C +  G F C+C
Sbjct: 1118 CE-DIDECSLSDGLCPHGQCVNVIGAFQCSC 1147



 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 53/108 (49%), Gaps = 8/108 (7%)
 Frame = +2

Query: 254  LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CE 415
            LC+CP GY     GR C+ D+DEC+          CV+ V  +TC C   G+T     C 
Sbjct: 2435 LCSCPRGYLLEEDGRTCK-DLDECTSRQHNCQF-LCVNTVGAFTCRCPP-GFTQHHQACF 2491

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC-QPATPGSTATGCRRVRQ 553
             N +EC      CG HG C++T G F C C Q  T  S+  GC  V +
Sbjct: 2492 DN-DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE 2538



 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECEEDRALCGHGVC 469
            D+DEC        GG CV+   ++ C+C    +       CE +++EC     +CG G C
Sbjct: 1570 DIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSGICGPGTC 1628

Query: 470  YDTYGGFVCAC 502
            Y+T G + C C
Sbjct: 1629 YNTLGNYTCVC 1639



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
            C C  G+      RNC TD+DEC  +      G CV+   ++ C+C     +G     N 
Sbjct: 1018 CACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNC 1076

Query: 422  --VNECEEDRALCGHGVCYDTYGGFVCACQP 508
              V+EC  D  LC  G C +T G + C C P
Sbjct: 1077 MDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1107



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/105 (35%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCE 415
            C+C  GY+    GR C  DVDEC       + G C +    + C C   G+      R  
Sbjct: 1186 CSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCLCY-DGFMATPDMRTC 1243

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
             +V+EC+ +  +C HG C +T G FVC CQ        ATGC  V
Sbjct: 1244 VDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDV 1288



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
 Frame = +2

Query: 257  CTCPPGYTGRNCET-DVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGAR--CETNV 424
            C C PG+ G   E  D+DEC S    C   G C++   +Y C C   G+ G    CE   
Sbjct: 1313 CRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQ-GFAGDGFFCEDR- 1370

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQ 505
            +EC E+  LC +G C +  GG+ C C+
Sbjct: 1371 DECAENVDLCDNGQCLNAPGGYRCECE 1397



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 38/106 (35%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG----ARC 412
            C C  G+T    G  CE DV+EC G   C +G  C + +  Y C C   G+T     A+C
Sbjct: 2518 CECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQNQLGGYRCSCPQ-GFTQHSQWAQC 2573

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT-GCRRV 547
              + NEC      CG   C +T GGF C C        A  GC+ V
Sbjct: 2574 -VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDV 2618



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYTG---RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCET 418
           C C PG+     R    DVDEC  +    + GRCV+   ++ C C A       G  C  
Sbjct: 479 CRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-V 537

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC     +C +GVC +  G F C C+P
Sbjct: 538 DHNECATS-TMCVNGVCLNEDGSFSCLCKP 566



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
            C CP GY    TG NC  D DECS    C   G C + +  + C C A G+      T  
Sbjct: 2116 CECPFGYSLDFTGINC-VDTDECSVGHPC-GQGTCTNVIGGFECAC-ADGFEPGLMMTCE 2172

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC  +  LC    C++T G ++C C
Sbjct: 2173 DIDECSLNPLLCAFR-CHNTEGSYLCTC 2199



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
 Frame = +2

Query: 278  TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA--RCETNVNECEEDRAL 451
            +GR    DV+EC         G C + V ++ C C       A  R  T+++EC     L
Sbjct: 986  SGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1045

Query: 452  CGHGVCYDTYGGFVCACQP 508
            CG G C +T G F C C P
Sbjct: 1046 CGQGTCVNTPGSFECECFP 1064



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE--- 415
            C CPPG+     G  CE D+DECS +      G+CV+ +  + C C A G+         
Sbjct: 1103 CQCPPGHELTAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHA-GFQSTPDRQGC 1160

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCAC 502
             ++NEC      C  H  C +T G + C+C
Sbjct: 1161 VDINECRVQNGGCDVH--CINTEGSYRCSC 1188



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G+     G+NC  D +EC   A     G C +   ++ C C       +    ++
Sbjct: 1919 CLCQDGFELTADGKNC-VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDI 1977

Query: 425  NECEEDRALCGHGVCYDTYGGFVCACQP 508
            +EC E+  LC  G C ++ G F C C P
Sbjct: 1978 DECSEEPNLCLFGTCTNSPGSFQCLCPP 2005



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRALCGHGVC 469
            DV+EC+        G CV+   ++ C+C    +  +TG  C  + +EC      CG G C
Sbjct: 2091 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC-VDTDECSVGHP-CGQGTC 2148

Query: 470  YDTYGGFVCAC 502
             +  GGF CAC
Sbjct: 2149 TNVIGGFECAC 2159



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            C C  G+      R C+ DVDEC+    C  G  C +    + C C   GY     G  C
Sbjct: 1394 CECEMGFDPTEDHRACQ-DVDECAQGNLCAFGS-CENLPGMFRCICNG-GYELDRGGGNC 1450

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGC 538
             T++NEC  D   C +GVC +T G ++C+C Q      +  GC
Sbjct: 1451 -TDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGC 1491



 Score = 50.4 bits (115), Expect = 5e-06
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +G++C TDVDEC+  +   + G C ++  +Y+C C    +     E   
Sbjct: 714 CVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 772

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPAT 514
           +V+EC      C  GVC +  G + C C P +
Sbjct: 773 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGS 802



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET---NV 424
            LC    GYT      DVDEC   A     G C++++ ++ C C A GYT     T   ++
Sbjct: 2357 LCPHGSGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQA-GYTPDATATTCLDM 2413

Query: 425  NECEEDRALCGHGVCYDTYGGFVCAC 502
            +EC +    C   +C +T G F+C+C
Sbjct: 2414 DECSQVPKPCTF-LCKNTKGSFLCSC 2438



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
 Frame = +2

Query: 221 QLQRAPRRRHLLCTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA--- 388
           QL  A         C  G        D++EC+     C NG  C +   +Y C C     
Sbjct: 663 QLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYE 721

Query: 389 TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            G +G  C T+V+EC  +  LC +G C ++ G + C+C P
Sbjct: 722 AGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPP 760



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+     G+NC  D +EC+ +  C+NG  C++   +++C C   G+    G    
Sbjct: 521 CVCNAGFELSPDGKNC-VDHNECATSTMCVNGV-CLNEDGSFSCLCKP-GFLLAPGGHYC 577

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +++EC+    +C +G C +T G F C C
Sbjct: 578 MDIDECQTP-GICVNGHCTNTEGSFRCQC 605



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA 388
            C CPPGY      R CE D+DECS  +     G C + + NYTC C A
Sbjct: 1595 CECPPGYHLSEHTRICE-DIDECSTHSGICGPGTCYNTLGNYTCVCPA 1641



 Score = 45.6 bits (103), Expect = 1e-04
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C C  GY    G  C    +EC       + G C+D   +Y C C   G+  +  +T   
Sbjct: 1796 CKCTRGYKLSPGGAC-VGQNECREIPNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCM 1853

Query: 428  ECEE-DRALCGHGVCYDTYGGFVCACQP 508
            + +E DR  CG+G C +  G + C C P
Sbjct: 1854 DIDECDRQPCGNGTCKNIIGSYNCLCFP 1881



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 14/94 (14%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCA--SAACRHGARCVEDGRGDYSCDCPPGYH---- 152
           Y C C   Y    +G +C  D  D CA  S  C +G  C ++  G YSC CPPG+H    
Sbjct: 712 YRCVCNLGYEAGASGKDC-TDV-DECALNSLLCDNGW-C-QNSPGSYSCSCPPGFHFWQD 767

Query: 153 GTYC-ELEVSLDPLCVAGPCRN---NGSCSVPPG 242
              C +++  L   CV+G CRN   + +C   PG
Sbjct: 768 TEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPG 801



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
 Frame = +2

Query: 257  CTCPPGYTG----RNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYT---GARC 412
            C C  G+      R C  DVDEC      CL+G  C +   ++ C C   GY    GA  
Sbjct: 1228 CLCYDGFMATPDMRTC-VDVDECDLNPHICLHGD-CENTKGSFVCHCQL-GYMVRKGATG 1284

Query: 413  ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATPG 520
             ++V+ECE     C  H  C +  G F C C P   G
Sbjct: 1285 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVG 1321



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 329 CLNGGRCVDAVNNYTCDCTATGYT-GARCE-TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           CLNG RC+   ++Y C+C   GYT   R E  +V+EC    + C HG C +  G + C C
Sbjct: 426 CLNG-RCLPTPSSYRCECN-VGYTQDVRGECIDVDECTS--SPCHHGDCVNIPGTYHCRC 481

Query: 503 QP---ATP 517
            P   ATP
Sbjct: 482 YPGFQATP 489



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +2

Query: 389  TGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
            +GYT      +V+EC     LC HG C ++ G F C CQ   TP +TAT C
Sbjct: 2362 SGYTAEG--RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2410



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRN----CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR----C 412
            C+CP G+T  +    C  D +EC+ +        C + +  + C C + G+   +    C
Sbjct: 2558 CSCPQGFTQHSQWAQC-VDENECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGC 2615

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            + +V+EC   R  C +  C +T GGF+C C
Sbjct: 2616 Q-DVDECAGRRGPCSYS-CANTPGGFLCGC 2643



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 28/76 (36%), Positives = 32/76 (42%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C       +C V  G  C S +C +G  C    RG  SC C  GY GT C       P
Sbjct: 108 CTCADGTLAPSCGVSRGSGC-SVSCMNGGTC----RGA-SCLCQKGYTGTVCG-----QP 156

Query: 189 LCVAGPCRNNGSCSVP 236
           +C  G C N G C  P
Sbjct: 157 ICDRG-CHNGGRCIGP 171



 Score = 41.9 bits (94), Expect = 0.002
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCTA-TGYTG--ARCETNVNECEEDRALCGHGV- 466
            D+DEC    A    G C++ + ++ C+C A   Y      CE +V+EC    + C     
Sbjct: 1728 DIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNAD 1786

Query: 467  CYDTYGGFVCAC---QPATPGSTATGCRRVRQ 553
            C +  G + C C      +PG    G    R+
Sbjct: 1787 CINIPGSYRCKCTRGYKLSPGGACVGQNECRE 1818



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = +3

Query: 3   YECHCTARYTGN-NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYC-ELEV 176
           Y C C   YT +   E    D C S+ C HG  CV    G Y C C PG+  T   +  V
Sbjct: 438 YRCECNVGYTQDVRGECIDVDECTSSPCHHGD-CVNIP-GTYHCRCYPGFQATPTRQACV 495

Query: 177 SLDPLCVAGPCRNNGSC 227
            +D   V+G   + G C
Sbjct: 496 DVDECIVSGGLCHLGRC 512



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 27/78 (34%), Positives = 35/78 (44%)
 Frame = +2

Query: 266 PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDR 445
           P  +TG  C+ DVDEC        GG CV+ V ++ C C      G R   +   CE+ R
Sbjct: 245 PNIHTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRCP----VGHRLSDSSAACEDYR 298

Query: 446 ALCGHGVCYDTYGGFVCA 499
           A    G C+    G  CA
Sbjct: 299 A----GACFSVLFGGRCA 312



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 21/65 (32%), Positives = 27/65 (41%)
 Frame = +2

Query: 308  ECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGG 487
            EC        G  C     +  C       TG  C+ +VNECE    +C +G C +T G 
Sbjct: 840  ECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPNGRCVNTAGS 898

Query: 488  FVCAC 502
            F C C
Sbjct: 899  FRCEC 903



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
 Frame = +3

Query: 3   YECHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           ++C C A +     G NC VD  +   S  C +G    EDG   +SC C PG+     G 
Sbjct: 519 FQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAPGGH 575

Query: 159 YC-ELEVSLDP-LCVAGPCRN 215
           YC +++    P +CV G C N
Sbjct: 576 YCMDIDECQTPGICVNGHCTN 596



 Score = 39.1 bits (87), Expect = 0.013
 Identities = 34/85 (40%), Positives = 37/85 (43%), Gaps = 14/85 (16%)
 Frame = +3

Query: 3    YECHCTARYTGN-----NCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGYH--- 152
            +EC C   Y        NC +D  D CA     CR G  C     G Y C CPPG+    
Sbjct: 1058 FECECFPGYESGFMLMKNC-MDV-DECARDPLLCR-GGTCTNTD-GSYKCQCPPGHELTA 1113

Query: 153  -GTYCE--LEVSL-DPLCVAGPCRN 215
             GT CE   E SL D LC  G C N
Sbjct: 1114 KGTACEDIDECSLSDGLCPHGQCVN 1138



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/60 (33%), Positives = 24/60 (40%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
           C C   YTG  C    G P     C +G RC+    G   C C  G+ G  CE +    P
Sbjct: 142 CLCQKGYTGTVC----GQPICDRGCHNGGRCI----GPNRCACVYGFMGPQCERDYRTGP 193



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCET---DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            +C C  G+     +T   D+DEC     C NG  C + + +Y C C   G+       C 
Sbjct: 1836 MCLCHRGFQASADQTLCMDIDECD-RQPCGNG-TCKNIIGSYNCLCFP-GFVVTHNGDC- 1891

Query: 416  TNVNECEE-DRALCGHGVCYDTYGGFVCACQ 505
             + +EC      +C  G C +T G F C CQ
Sbjct: 1892 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQ 1922



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 13/30 (43%), Positives = 19/30 (63%)
 Frame = +2

Query: 419  NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+E   LC  G C +T+G F C C P
Sbjct: 1570 DIDECQELPGLCQGGDCVNTFGSFQCECPP 1599



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 10/80 (12%)
 Frame = +3

Query: 33   GNNCEVDAGDPCASAA--CRHGARCVEDGRGDYSCDCPPGY--HGTYC-EL-EVSLDP-L 191
            G NC VD  + C S A  C  G  C ++  G + C CPPG+     +C ++ E S +P L
Sbjct: 1931 GKNC-VDTNE-CLSLAGTCLPGT-C-QNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNL 1986

Query: 192  CVAGPCRNN-GS--CSVPPG 242
            C+ G C N+ GS  C  PPG
Sbjct: 1987 CLFGTCTNSPGSFQCLCPPG 2006



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
 Frame = +3

Query: 6    ECH--CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC--- 164
            ECH   T   +G+ CE D  +      C+HG    ++  G Y C CP G+  H  +    
Sbjct: 2519 ECHQGFTLVSSGHGCE-DVNECDGPHRCQHGC---QNQLGGYRCSCPQGFTQHSQWAQCV 2574

Query: 165  -ELEVSLD-PLCVAGPCRNN-GS--CSVPPGGD 248
             E E +L  P C +  CRN  G   C  P G D
Sbjct: 2575 DENECALSPPTCGSASCRNTLGGFRCVCPSGFD 2607



 Score = 35.1 bits (77), Expect = 0.21
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           C C  GYTG  C   +  C     C NGGRC+   N   C     G+ G +CE
Sbjct: 142 CLCQKGYTGTVCGQPI--CD--RGCHNGGRCI-GPNRCAC---VYGFMGPQCE 186



 Score = 33.9 bits (74), Expect = 0.49
 Identities = 13/35 (37%), Positives = 19/35 (54%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           TG  C+ DV+EC         GRCV+   ++ C+C
Sbjct: 870 TGVTCD-DVNECESFPGVCPNGRCVNTAGSFRCEC 903



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 29/79 (36%), Positives = 37/79 (46%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYCE--LEVSLDP-LC 194
           N C +D  + CA+  C       E+ RG Y C C  GY     G  C    E +L+  LC
Sbjct: 691 NECALDP-EVCANGVC-------ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLC 742

Query: 195 VAGPCRNNG---SCSVPPG 242
             G C+N+    SCS PPG
Sbjct: 743 DNGWCQNSPGSYSCSCPPG 761



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 11/65 (16%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCEL-------EVSLDP-LCVAGPCRN-NGS--C 227
            C  G  CV    G + C+C PGY   +  +       E + DP LC  G C N +GS  C
Sbjct: 1046 CGQGT-CVNTP-GSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC 1103

Query: 228  SVPPG 242
              PPG
Sbjct: 1104 QCPPG 1108



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
 Frame = +3

Query: 9    CHCTARYT----GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYC-- 164
            C C   Y     G  C+ D  D C S        CV    G ++C CPPG+  H   C  
Sbjct: 2436 CSCPRGYLLEEDGRTCK-DL-DECTSRQHNCQFLCVNTV-GAFTCRCPPGFTQHHQACFD 2492

Query: 165  ELEVSLDPLCVAGPCRNNGSCSVPPG 242
              E S  P    GPC  +G C   PG
Sbjct: 2493 NDECSAQP----GPCGAHGHCHNTPG 2514



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +2

Query: 395 YTGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +TGA C+ +V+EC+    LC  G C +  G F C C
Sbjct: 248 HTGA-CQ-DVDECQAVPGLCQGGSCVNMVGSFHCRC 281



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELE-VSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  CV    G + C+CP GY   +  +  V  D   V  PC   G+C+   GG
Sbjct: 2102 CTNGV-CVNTD-GSFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTNVIGG 2154



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +3

Query: 90   GARCVEDGRGDYSCDCPPGYH 152
            G  CV    G + C+CPPGYH
Sbjct: 1583 GGDCVNTF-GSFQCECPPGYH 1602



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
 Frame = +3

Query: 27   YTGNNCEVD-AGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAG 203
            +TG   ++D  G+    A C +G  C+    G + C+CP G++  Y  + ++ + +   G
Sbjct: 1722 HTGKPLDIDECGE--IPAICANGI-CINQ-IGSFRCECPAGFN--YNSILLACEDVDECG 1775

Query: 204  ----PCRNNGSCSVPPG 242
                PC+ N  C   PG
Sbjct: 1776 SRESPCQQNADCINIPG 1792


>L32137-1|AAA57253.1|  757|Homo sapiens matrix protein protein.
          Length = 757

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC +T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRGAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 7/84 (8%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE--LEVSLDPLCVAGPCRNNG---S 224
           CA   C  G  C++   G     CP G+  +G++C    E +  P      C N      
Sbjct: 91  CAPGFCFPGVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFR 150

Query: 225 CSVPPGGDTYSAPVRQDTRVVTAR 296
           C   P G  YS P  Q   +  A+
Sbjct: 151 CEACPPG--YSGPTHQGVGLAFAK 172


>BC125092-1|AAI25093.1|  757|Homo sapiens cartilage oligomeric
           matrix protein protein.
          Length = 757

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC +T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160


>BC110847-1|AAI10848.1|  757|Homo sapiens cartilage oligomeric
           matrix protein protein.
          Length = 757

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC +T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160


>AC003107-1|AAB86501.1|  817|Homo sapiens COMP_HUMAN protein.
          Length = 817

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC +T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160


>AB086984-1|BAC53888.1|  757|Homo sapiens cartilage oligomeric
           matrix protein protein.
          Length = 757

 Score = 63.7 bits (148), Expect = 5e-10
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC +T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRGAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 7/84 (8%)
 Frame = +3

Query: 66  CASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE--LEVSLDPLCVAGPCRNNG---S 224
           CA   C  G  C++   G     CP G+  +G++C    E +  P      C N      
Sbjct: 91  CAPGFCFPGVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFR 150

Query: 225 CSVPPGGDTYSAPVRQDTRVVTAR 296
           C   P G  YS P  Q   +  A+
Sbjct: 151 CEACPPG--YSGPTHQGVGLAFAK 172


>X62009-1|CAB56757.1|  754|Homo sapiens fibrillin 5 protein.
          Length = 754

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 35/104 (33%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C+C  GY     GR+C  D+DEC       +GG+C +    Y C C          +T  
Sbjct: 514 CSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 572

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
           +VNEC+ +  +C  G C +T G F+C CQ   +     TGC  V
Sbjct: 573 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDV 616



 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET-DVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-TNVN 427
           C+C  G+ G   +  D DECS G   C    +CV+   +Y C C+  G+TG     ++V+
Sbjct: 641 CSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSE-GFTGDGFTCSDVD 699

Query: 428 ECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCR 541
           EC E+  LC +G C +  G + C C+   TP S +  C+
Sbjct: 700 ECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 738



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C C  GY    +GRNC  D+DEC       + G C +   +Y+C C          ET  
Sbjct: 41  CNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCE 99

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATP-GSTATGC 538
           ++NECE +   C +G C +  G F C C P +   ST   C
Sbjct: 100 DINECESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLIC 138



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
 Frame = +2

Query: 278 TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCT---ATGYTGARCETNVNECEEDRA 448
           TGR    D++EC         G+C + + ++ C C    A       C T+++EC     
Sbjct: 314 TGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC-TDIDECRISPD 372

Query: 449 LCGHGVCYDTYGGFVCAC 502
           LCG G+C +T G F C C
Sbjct: 373 LCGSGICVNTPGSFECEC 390



 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
 Frame = +2

Query: 257 CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-- 415
           C C  GY       +NC  D+D C        GG CV+   ++ CDC          E  
Sbjct: 388 CECFEGYESGFMMMKNC-MDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 446

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP---ATP 517
            ++NEC     LC +G C +  G + C+C P   ATP
Sbjct: 447 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 483



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 4/99 (4%)
 Frame = +2

Query: 248 HLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCE 415
           H LC+   G T      D++EC+        G C +   +Y C+C + GY    +G  C 
Sbjct: 1   HGLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNS-GYEPDASGRNC- 56

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTAT 532
            +++EC  +R LC +G+C +T G + C C P     T T
Sbjct: 57  IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTET 95



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 13/93 (13%)
 Frame = +3

Query: 3   YECHCTARY----TGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY----HGT 158
           Y C+C + Y    +G NC +D  +   +        C  +  G YSC CPPGY       
Sbjct: 39  YRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLC-RNTPGSYSCTCPPGYVFRTETE 96

Query: 159 YCE--LEVSLDPLCVAGPCRNN-GS--CSVPPG 242
            CE   E   +P CV G CRNN GS  C   PG
Sbjct: 97  TCEDINECESNP-CVNGACRNNLGSFNCECSPG 128



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
 Frame = +2

Query: 287 NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           N  T   EC        G  C     +  C        G  CE +VNECE    +C +G 
Sbjct: 160 NGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGR 218

Query: 467 CYDTYGGFVCAC-QPATPGSTATGCRRVRQD 556
           C ++ G F C C +  T   T   C  +R +
Sbjct: 219 CVNSKGSFHCECPEGLTLDGTGRVCLDIRME 249



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
 Frame = +2

Query: 257 CTCPPGYTG----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  G+      + C  DV+EC   +     G C +   ++ C C   GY+   G    
Sbjct: 556 CLCYDGFMASMDMKTC-IDVNECDLNSNICMFGECENTKGSFICHCQL-GYSVKKGTTGC 613

Query: 416 TNVNECEEDRALCG-HGVCYDTYGGFVCACQPATPGS 523
           T+V+ECE     C  H  C +  G F C+C+    G+
Sbjct: 614 TDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN 650



 Score = 35.9 bits (79), Expect = 0.12
 Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 10/79 (12%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYH----GTYC-ELEVSL--DPLC 194
           N C +D  D CA+  C       E+ RG Y C+C  GY     G  C +++  L    LC
Sbjct: 18  NECALDP-DICANGIC-------ENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLC 69

Query: 195 VAGPCRN---NGSCSVPPG 242
             G CRN   + SC+ PPG
Sbjct: 70  DNGLCRNTPGSYSCTCPPG 88



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCAS--AACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C+  +TG+       D CA     C +G +C+ +  G Y C+C  G+
Sbjct: 680 YRCACSEGFTGDGFTCSDVDECAENINLCENG-QCL-NVPGAYRCECEMGF 728



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3   YECHCTARYTGN-----NCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCE 167
           +EC C   Y        NC    G       CR G  CV    G + CDCP G+  +   
Sbjct: 386 FECECFEGYESGFMMMKNCMDIDGCERNPLLCR-GGTCVNT-EGSFQCDCPLGHELSPSR 443

Query: 168 ------LEVSL-DPLCVAGPCRN---NGSCSVPPG 242
                  E SL D LC  G C N      CS  PG
Sbjct: 444 EDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPG 478


>AK223216-1|BAD96936.1|  757|Homo sapiens cartilage oligomeric
           matrix protein precursor variant protein.
          Length = 757

 Score = 63.3 bits (147), Expect = 7e-10
 Identities = 39/114 (34%), Positives = 54/114 (47%), Gaps = 17/114 (14%)
 Frame = +2

Query: 263 CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE-------- 415
           CP G+TG     TDV+EC+ A  C    RC++    + C+    GY+G   +        
Sbjct: 114 CPAGFTGNGSHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172

Query: 416 ------TNVNECEEDRALC-GHGVCYDTYGGFVCA-CQPATPGSTATGCRRVRQ 553
                 T++NECE  +  C  + VC  T G F C  CQP   G  A+GC+R  Q
Sbjct: 173 ANKQVCTDINECETGQHNCVPNSVCISTRGSFQCGPCQPGFVGDQASGCQRRAQ 226



 Score = 36.7 bits (81), Expect = 0.069
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
 Frame = +3

Query: 15  CTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCD-CPPGYHG 155
           C A +TGN       + C +  C    RC+    G + C+ CPPGY G
Sbjct: 114 CPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG-FRCEACPPGYSG 160


>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
          Length = 1821

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
 Frame = +2

Query: 269  PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE 439
            P   G +CE DVDEC    +   GG C + V +Y C C   G+    G  CE +VNEC  
Sbjct: 1126 PSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQ-GFQLANGTVCE-DVNECMG 1182

Query: 440  DRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            +     HG C +++G F C C P        T C+ V
Sbjct: 1183 EEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV 1219



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETN 421
            C C  GY      +C+ D++EC     C +G RCV++  +YTC     GY G    C  +
Sbjct: 954  CECDQGYIMVRKGHCQ-DINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQSGSC-VD 1010

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRV 547
            VNEC     +C HG C +  G F C+C Q     S   GC+ V
Sbjct: 1011 VNECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE---TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C C PGY     +   TD +EC     C   GRC++ V +Y+C C   GYT    GA  E
Sbjct: 870  CVCSPGYQLHPSQAYCTDDNECL-RDPCQGKGRCINRVGSYSCFC-YPGYTLATSGATQE 927

Query: 416  -TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              ++NECE+   +C  G C +T G + C C
Sbjct: 928  CQDINECEQP-GVCSGGQCTNTEGSYHCEC 956



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C CP G+    G  CE DV+EC G   C   G C+++  ++ C C A G+  A   T+  
Sbjct: 1160 CLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLC-APGFVSAEGGTSCQ 1217

Query: 428  ECEEDRAL--CGHGVCYDTYGGFVCACQPATPGSTATG 535
            + +E      C  G C +T G F C C+     S  +G
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESG 1255



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
 Frame = +2

Query: 263  CPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTC-DCTATGYT----GARCE 415
            C  GY     G  CE D+DEC+    C +G  C +   +++C DC   GY     G  CE
Sbjct: 1078 CENGYWVNEDGTACE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDG-GYRPSPLGDSCE 1134

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +V+ECE+ ++ C  G C +T G + C C      +  T C  V +
Sbjct: 1135 -DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNE 1179



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +2

Query: 266  PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECE 436
            P G+ G   E    EC     C NG RCV     YTCDC       A    C  +VNEC+
Sbjct: 1726 PAGFEGLQAE----ECGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMAC-VDVNECD 1779

Query: 437  E---DRALCGHGVCYDTYGGFVCACQP 508
            +      LC HG C +T G + C C P
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSP 1806



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
            + +P     +  C PG+      +C  D+DEC+    C + G C +   ++ C C   G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQ-GF 1334

Query: 398  ----TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                +G  C  +VNECE   A+CG  +C +  G F+C C
Sbjct: 1335 EISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
 Frame = +2

Query: 281  GRNCETDVDECS--GAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDR 445
            G+   TD DEC   G   C NG RC++ V  Y C C    +  A   +CE + +EC++  
Sbjct: 1479 GQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDASHKKCEDH-DECQD-- 1534

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
              C +G C +T G F C C P
Sbjct: 1535 LACENGECVNTEGSFHCFCSP 1555



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEE 439
            C  GY G++    DV+EC     C +G +C +   ++ C C   GY     E    + +E
Sbjct: 997  CEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ-GYEVTSDEKGCQDVDE 1054

Query: 440  --DRALCGHGVCYDTYGGFVC-ACQ 505
               RA C  G+C +T G F C AC+
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACE 1079



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
 Frame = +2

Query: 302  VDECSGAAACLNG-GRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRALCGHGV 466
            +D C+  A  + G G CV+  + Y C C + GY    + A C T+ NEC  D    G G 
Sbjct: 845  IDRCAAGATNVCGPGTCVNLPDGYRCVC-SPGYQLHPSQAYC-TDDNECLRDPCQ-GKGR 901

Query: 467  CYDTYGGFVCACQP----ATPGST 526
            C +  G + C C P    AT G+T
Sbjct: 902  CINRVGSYSCFCYPGYTLATSGAT 925



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
 Frame = +3

Query: 60   DPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D CA+ A   C  G  CV    G Y C C PGY     +   + D  C+  PC+  G C
Sbjct: 846  DRCAAGATNVCGPGT-CVNLPDG-YRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRC 902



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDP--CASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C+  Y  +  +    D   C    C+   RC+ +  G YSC C PGY
Sbjct: 868  YRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRCI-NRVGSYSCFCYPGY 917


>X62008-1|CAB56534.1|  517|Homo sapiens fibrillin 15 protein.
          Length = 517

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G+      RNC TD+DEC  +      G+CV+   ++ C C     +G+   +  
Sbjct: 257 CRCDSGFALDSEERNC-TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC 315

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            +++EC+ D  LC  GVC++T G + C C P
Sbjct: 316 MDIDECQRDPLLCRGGVCHNTEGSYRCECPP 346



 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET-- 418
           C+C PG+      R+C TD+DEC       +GG+C +    Y C C          +T  
Sbjct: 425 CSCQPGFALMPDQRSC-TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCV 483

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           +VNEC+ +  +C  G C +T G F+C C     G
Sbjct: 484 DVNECDLNPNICLSGTCENTKGSFICHCDMGYSG 517



 Score = 56.8 bits (131), Expect = 6e-08
 Identities = 29/91 (31%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
 Frame = +2

Query: 257 CTCPPGYTG-----RNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCET- 418
           C C  GY       +NC  D+DEC        GG C +   +Y C+C             
Sbjct: 299 CKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISAC 357

Query: 419 -NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
            ++NECE    LC +G C +  G + CAC P
Sbjct: 358 IDINECELSAHLCPNGRCVNLIGKYQCACNP 388



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYT-GRNCET--DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---T 418
           C CPPG+    N     D++EC  +A     GRCV+ +  Y C C   GY          
Sbjct: 342 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCV 400

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           +++EC      C    C ++ G + C+CQP
Sbjct: 401 DIDECSIMNGGC-ETFCTNSEGSYECSCQP 429



 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
 Frame = +2

Query: 254 LCTCPPGYT------GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGA 406
           LC   PG+       G+    D++EC    +    G+C + + ++ C C  +G+   +  
Sbjct: 211 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD-SGFALDSEE 269

Query: 407 RCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           R  T+++EC     LCG G C +T G F C C
Sbjct: 270 RNCTDIDECRISPDLCGRGQCVNTPGDFECKC 301



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 24/83 (28%), Positives = 37/83 (44%)
 Frame = +2

Query: 287 NCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           N  T   +C  +     G  C     +  C    +   G +CE +++ECE    +C +G+
Sbjct: 71  NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-DIDECEVFPGVCKNGL 129

Query: 467 CYDTYGGFVCACQPATPGSTATG 535
           C +T G F C C P+     ATG
Sbjct: 130 CVNTRGSFKCQC-PSGMTLDATG 151



 Score = 33.1 bits (72), Expect = 0.85
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGD--PCASAA--CRHGARCVEDGRGDYSCDCPPGYHGTYCEL 170
           ++C C + +  ++ E +  D   C  +   C  G +CV    GD+ C C  GY   +  +
Sbjct: 255 FKCRCDSGFALDSEERNCTDIDECRISPDLCGRG-QCVNTP-GDFECKCDEGYESGFMMM 312

Query: 171 -------EVSLDP-LCVAGPCRN-NGS--CSVPPG 242
                  E   DP LC  G C N  GS  C  PPG
Sbjct: 313 KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPG 347



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 18/41 (43%), Positives = 21/41 (51%)
 Frame = +3

Query: 36  NNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGT 158
           N CE+ A        C +G RCV +  G Y C C PGYH T
Sbjct: 361 NECELSAH------LCPNG-RCV-NLIGKYQCACNPGYHST 393


>U57523-1|AAB06946.1|  446|Homo sapiens protein ( Human nel homolog
           mRNA, partial cds. ).
          Length = 446

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTA-------TGYTGARC 412
           C CP G+TG +CE D+DECS G   C N  RCV+    + C+C +          +G  C
Sbjct: 153 CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWHHCECRSGFHDDGTYSLSGESC 212

Query: 413 ETNVNECEEDRALC-GHGVCYDTYGGFVCACQPATP 517
             +++EC      C     C +  GGF C C P  P
Sbjct: 213 -IDIDECALRTHTCWNDSACINLAGGFDCLC-PCGP 246



 Score = 53.2 bits (122), Expect = 7e-07
 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
 Frame = +2

Query: 257 CTCPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNE 430
           CTC PGY G    C    +E      C  GG CV A N   C    +G+TG+ CE +++E
Sbjct: 120 CTCKPGYVGNGTICRAFCEE-----GCRYGGTCV-APNKCVC---PSGFTGSHCEKDIDE 170

Query: 431 CEEDRALC-GHGVCYDTYGGFVCACQ 505
           C E    C  H  C +  G   C C+
Sbjct: 171 CSEGIIECHNHSRCVNLPGWHHCECR 196



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 5/89 (5%)
 Frame = +2

Query: 290 CETDVDECSGAAA-CLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDRALCG 457
           CE D+DEC+     C     CV+    Y CDC   GY       C T  +EC   +  C 
Sbjct: 50  CE-DIDECAAKMHYCHANTVCVNLPGLYRCDCVP-GYIRVDDFSC-TEHDECGSGQHNCD 106

Query: 458 -HGVCYDTYGGFVCACQPATPGSTATGCR 541
            + +C +T  G  C C+P   G+  T CR
Sbjct: 107 ENAICTNTVQGHSCTCKPGYVGN-GTICR 134



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           + C C   Y GN     A        CR+G  CV   +    C CP G+ G++CE ++  
Sbjct: 118 HSCTCKPGYVGNGTICRA---FCEEGCRYGGTCVAPNK----CVCPSGFTGSHCEKDID- 169

Query: 183 DPLCVAG--PCRNNGSCSVPPG 242
              C  G   C N+  C   PG
Sbjct: 170 --ECSEGIIECHNHSRCVNLPG 189


>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
            factor-beta-binding protein-2 protein.
          Length = 1821

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
 Frame = +2

Query: 269  PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE 439
            P   G +CE DVDEC    +   GG C + V +Y C C   G+    G  CE +VNEC  
Sbjct: 1126 PSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQ-GFQLANGTVCE-DVNECMG 1182

Query: 440  DRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            +     HG C +++G F C C P        T C+ V
Sbjct: 1183 EEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV 1219



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETN 421
            C C  GY      +C+ D++EC     C +G RCV++  +YTC     GY G    C  +
Sbjct: 954  CECDQGYIMVRKGHCQ-DINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQSGSC-VD 1010

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRV 547
            VNEC     +C HG C +  G F C+C Q     S   GC+ V
Sbjct: 1011 VNECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE---TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C C PGY     +   TD +EC     C   GRC++ V +Y+C C   GYT    GA  E
Sbjct: 870  CVCSPGYQLHPSQAYCTDDNECL-RDPCKGKGRCINRVGSYSCFC-YPGYTLATSGATQE 927

Query: 416  -TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              ++NECE+   +C  G C +T G + C C
Sbjct: 928  CQDINECEQP-GVCSGGQCTNTEGSYHCEC 956



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C CP G+    G  CE DV+EC G   C   G C+++  ++ C C A G+  A   T+  
Sbjct: 1160 CLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLC-APGFVSAEGGTSCQ 1217

Query: 428  ECEEDRAL--CGHGVCYDTYGGFVCACQPATPGSTATG 535
            + +E      C  G C +T G F C C+     S  +G
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESG 1255



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
 Frame = +2

Query: 263  CPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTC-DCTATGYT----GARCE 415
            C  GY     G  CE D+DEC+    C +G  C +   +++C DC   GY     G  CE
Sbjct: 1078 CENGYWVNEDGTACE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDG-GYRPSPLGDSCE 1134

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +V+ECE+ ++ C  G C +T G + C C      +  T C  V +
Sbjct: 1135 -DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNE 1179



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +2

Query: 266  PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECE 436
            P G+ G   E    EC     C NG RCV     YTCDC       A    C  +VNEC+
Sbjct: 1726 PAGFEGLQAE----ECGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMAC-VDVNECD 1779

Query: 437  E---DRALCGHGVCYDTYGGFVCACQP 508
            +      LC HG C +T G + C C P
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSP 1806



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
            + +P     +  C PG+      +C  D+DEC+    C + G C +   ++ C C   G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQ-GF 1334

Query: 398  ----TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                +G  C  +VNECE   A+CG  +C +  G F+C C
Sbjct: 1335 EISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
 Frame = +2

Query: 281  GRNCETDVDECS--GAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDR 445
            G+   TD DEC   G   C NG RC++ V  Y C C    +  A   +CE + +EC++  
Sbjct: 1479 GQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDASHKKCEDH-DECQD-- 1534

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
              C +G C +T G F C C P
Sbjct: 1535 LACENGECVNTEGSFHCFCSP 1555



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEE 439
            C  GY G++    DV+EC     C +G +C +   ++ C C   GY     E    + +E
Sbjct: 997  CEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ-GYEVTSDEKGCQDVDE 1054

Query: 440  --DRALCGHGVCYDTYGGFVC-ACQ 505
               RA C  G+C +T G F C AC+
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACE 1079



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
 Frame = +2

Query: 302  VDECSGAAACLNG-GRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRALCGHGV 466
            +D C+  A  + G G CV+  + Y C C + GY    + A C T+ NEC  D    G G 
Sbjct: 845  IDRCAAGATNVCGPGTCVNLPDGYRCVC-SPGYQLHPSQAYC-TDDNECLRDPCK-GKGR 901

Query: 467  CYDTYGGFVCACQP----ATPGST 526
            C +  G + C C P    AT G+T
Sbjct: 902  CINRVGSYSCFCYPGYTLATSGAT 925



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
 Frame = +3

Query: 60   DPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D CA+ A   C  G  CV    G Y C C PGY     +   + D  C+  PC+  G C
Sbjct: 846  DRCAAGATNVCGPGT-CVNLPDG-YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRC 902



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDP--CASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C+  Y  +  +    D   C    C+   RC+ +  G YSC C PGY
Sbjct: 868  YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI-NRVGSYSCFCYPGY 917


>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
            factor beta binding protein 2 protein.
          Length = 1821

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
 Frame = +2

Query: 269  PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE 439
            P   G +CE DVDEC    +   GG C + V +Y C C   G+    G  CE +VNEC  
Sbjct: 1126 PSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQ-GFQLANGTVCE-DVNECMG 1182

Query: 440  DRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            +     HG C +++G F C C P        T C+ V
Sbjct: 1183 EEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV 1219



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETN 421
            C C  GY      +C+ D++EC     C +G RCV++  +YTC     GY G    C  +
Sbjct: 954  CECDQGYIMVRKGHCQ-DINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQSGSC-VD 1010

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRV 547
            VNEC     +C HG C +  G F C+C Q     S   GC+ V
Sbjct: 1011 VNECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 1052



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE---TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C C PGY     +   TD +EC     C   GRC++ V +Y+C C   GYT    GA  E
Sbjct: 870  CVCSPGYQLHPSQAYCTDDNECL-RDPCKGKGRCINRVGSYSCFC-YPGYTLATSGATQE 927

Query: 416  -TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              ++NECE+   +C  G C +T G + C C
Sbjct: 928  CQDINECEQP-GVCSGGQCTNTEGSYHCEC 956



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C CP G+    G  CE DV+EC G   C   G C+++  ++ C C A G+  A   T+  
Sbjct: 1160 CLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLC-APGFVSAEGGTSCQ 1217

Query: 428  ECEEDRAL--CGHGVCYDTYGGFVCACQPATPGSTATG 535
            + +E      C  G C +T G F C C+     S  +G
Sbjct: 1218 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESG 1255



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
 Frame = +2

Query: 263  CPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTC-DCTATGYT----GARCE 415
            C  GY     G  CE D+DEC+    C +G  C +   +++C DC   GY     G  CE
Sbjct: 1078 CENGYWVNEDGTACE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDG-GYRPSPLGDSCE 1134

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +V+ECE+ ++ C  G C +T G + C C      +  T C  V +
Sbjct: 1135 -DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNE 1179



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +2

Query: 266  PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECE 436
            P G+ G   E    EC     C NG RCV     YTCDC       A    C  +VNEC+
Sbjct: 1726 PAGFEGLQAE----ECGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMAC-VDVNECD 1779

Query: 437  E---DRALCGHGVCYDTYGGFVCACQP 508
            +      LC HG C +T G + C C P
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSP 1806



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
            + +P     +  C PG+      +C  D+DEC+    C + G C +   ++ C C   G+
Sbjct: 1277 ENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQ-GF 1334

Query: 398  ----TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                +G  C  +VNECE   A+CG  +C +  G F+C C
Sbjct: 1335 EISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC 1372



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
 Frame = +2

Query: 281  GRNCETDVDECS--GAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDR 445
            G+   TD DEC   G   C NG RC++ V  Y C C    +  A   +CE + +EC++  
Sbjct: 1479 GQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDASHKKCEDH-DECQD-- 1534

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
              C +G C +T G F C C P
Sbjct: 1535 LACENGECVNTEGSFHCFCSP 1555



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEE 439
            C  GY G++    DV+EC     C +G +C +   ++ C C   GY     E    + +E
Sbjct: 997  CEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ-GYEVTSDEKGCQDVDE 1054

Query: 440  --DRALCGHGVCYDTYGGFVC-ACQ 505
               RA C  G+C +T G F C AC+
Sbjct: 1055 CASRASCPTGLCLNTEGSFACSACE 1079



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
 Frame = +2

Query: 302  VDECSGAAACLNG-GRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRALCGHGV 466
            +D C+  A  + G G CV+  + Y C C + GY    + A C T+ NEC  D    G G 
Sbjct: 845  IDRCAAGATNVCGPGTCVNLPDGYRCVC-SPGYQLHPSQAYC-TDDNECLRDPCK-GKGR 901

Query: 467  CYDTYGGFVCACQP----ATPGST 526
            C +  G + C C P    AT G+T
Sbjct: 902  CINRVGSYSCFCYPGYTLATSGAT 925



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
 Frame = +3

Query: 60   DPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
            D CA+ A   C  G  CV    G Y C C PGY     +   + D  C+  PC+  G C
Sbjct: 846  DRCAAGATNVCGPGT-CVNLPDG-YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRC 902



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDP--CASAACRHGARCVEDGRGDYSCDCPPGY 149
            Y C C+  Y  +  +    D   C    C+   RC+ +  G YSC C PGY
Sbjct: 868  YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI-NRVGSYSCFCYPGY 917


>AF054502-1|AAC39882.1|  669|Homo sapiens latent transforming growth
           factor-beta binding protein 4 protein.
          Length = 669

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
 Frame = +2

Query: 263 CPPGY-TGRNCETDVDECS-GAAACLNGGRCVDAVNNYTCDCTATGYTGARCE----TNV 424
           CP G+   R   TDVDECS GA  C   G C +   ++ C C A GY           +V
Sbjct: 44  CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC-APGYRAPSGRPGPCADV 102

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           NEC E      HG C +T G F C C P   PG     C
Sbjct: 103 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 141



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 36/92 (39%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
 Frame = +2

Query: 257 CTCPPGY---TGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
           C+C PGY   +GR     DV+EC     C   G C++   ++ C C A GY     GA C
Sbjct: 83  CSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC-APGYRPGPRGASC 141

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
             +V+EC E+  LC  G+C +T G F C C P
Sbjct: 142 -LDVDECSEED-LCQSGICTNTDGSFECICPP 171



 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 35/95 (36%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
 Frame = +2

Query: 257 CTCPPGY-TGRNCET--DVDECSGAAACLNGG-RCVDAVNNYTC--DCTATGYTGAR--C 412
           C CPPG+  G +  +  DVDEC      L G  RC ++  +Y C  DC    + G    C
Sbjct: 167 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 226

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP 517
           + +VNECE  + +CG  +C +  G F+C C P +P
Sbjct: 227 D-DVNECETLQGVCGAALCENVEGSFLCVC-PNSP 259



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257 CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCET 418
           C C  GY   T R    D DEC+       GGRCV+ V +Y C C        +  RC +
Sbjct: 416 CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 475

Query: 419 NVNECEEDRALCGHGVCYDTYGG-FVCACQPATPGSTATGC 538
           N ++  +D      GVC+   G   VC+       +T T C
Sbjct: 476 NESQSLDDNL----GVCWQEVGADLVCSHPRLDRQATYTEC 512



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGR-----GDYSCDCPPGY----H 152
           + C C   Y   +       PCA    C  G  C   G      G ++C C PGY     
Sbjct: 81  FRCSCAPGYRAPS---GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 137

Query: 153 GTYC--ELEVSLDPLCVAGPCRN-NGS--CSVPPG 242
           G  C    E S + LC +G C N +GS  C  PPG
Sbjct: 138 GASCLDVDECSEEDLCQSGICTNTDGSFECICPPG 172


>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
            factor beta binding protein 2 variant protein.
          Length = 1700

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
 Frame = +2

Query: 269  PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE 439
            P   G +CE DVDEC    +   GG C + V +Y C C   G+    G  CE +VNEC  
Sbjct: 1005 PSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQ-GFQLANGTVCE-DVNECMG 1061

Query: 440  DRALCGHGVCYDTYGGFVCACQPA-TPGSTATGCRRV 547
            +     HG C +++G F C C P        T C+ V
Sbjct: 1062 EEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDV 1098



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 257  CTCPPGYT---GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG--ARCETN 421
            C C  GY      +C+ D++EC     C +G RCV++  +YTC     GY G    C  +
Sbjct: 833  CECDQGYIMVRKGHCQ-DINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQSGSC-VD 889

Query: 422  VNECEEDRALCGHGVCYDTYGGFVCAC-QPATPGSTATGCRRV 547
            VNEC     +C HG C +  G F C+C Q     S   GC+ V
Sbjct: 890  VNECLTP-GVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDV 931



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGYTGRNCE---TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARCE 415
            C C PGY     +   TD +EC     C   GRC++ V +Y+C C   GYT    GA  E
Sbjct: 749  CVCSPGYQLHPSQAYCTDDNECL-RDPCKGKGRCINRVGSYSCFC-YPGYTLATSGATQE 806

Query: 416  -TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
              ++NECE+   +C  G C +T G + C C
Sbjct: 807  CQDINECEQP-GVCSGGQCTNTEGSYHCEC 835



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 5/98 (5%)
 Frame = +2

Query: 257  CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVN 427
            C CP G+    G  CE DV+EC G   C   G C+++  ++ C C A G+  A   T+  
Sbjct: 1039 CLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLC-APGFVSAEGGTSCQ 1096

Query: 428  ECEEDRAL--CGHGVCYDTYGGFVCACQPATPGSTATG 535
            + +E      C  G C +T G F C C+     S  +G
Sbjct: 1097 DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESG 1134



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
 Frame = +2

Query: 263  CPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTC-DCTATGYT----GARCE 415
            C  GY     G  CE D+DEC+    C +G  C +   +++C DC   GY     G  CE
Sbjct: 957  CENGYWVNEDGTACE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDG-GYRPSPLGDSCE 1013

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCRRVRQ 553
             +V+ECE+ ++ C  G C +T G + C C      +  T C  V +
Sbjct: 1014 -DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNE 1058



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
 Frame = +2

Query: 266  PPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGAR---CETNVNECE 436
            P G+ G   E    EC     C NG RCV     YTCDC       A    C  +VNEC+
Sbjct: 1605 PAGFEGLQAE----ECGILNGCENG-RCVRVREGYTCDCFEGFQLDAAHMAC-VDVNECD 1658

Query: 437  E---DRALCGHGVCYDTYGGFVCACQP 508
            +      LC HG C +T G + C C P
Sbjct: 1659 DLNGPAVLCVHGYCENTEGSYRCHCSP 1685



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
 Frame = +2

Query: 227  QRAPRRRHLLCTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
            + +P     +  C PG+      +C  D+DEC+    C + G C +   ++ C C   G+
Sbjct: 1156 ENSPGSYRCVLGCQPGFHMAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQ-GF 1213

Query: 398  ----TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
                +G  C  +VNECE   A+CG  +C +  G F+C C
Sbjct: 1214 EISPSGWDC-VDVNECELMLAVCGAALCENVEGSFLCLC 1251



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
 Frame = +2

Query: 281  GRNCETDVDECS--GAAACLNGGRCVDAVNNYTCDCTATGYTGA---RCETNVNECEEDR 445
            G+   TD DEC   G   C NG RC++ V  Y C C    +  A   +CE + +EC++  
Sbjct: 1358 GQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDASHKKCEDH-DECQD-- 1413

Query: 446  ALCGHGVCYDTYGGFVCACQP 508
              C +G C +T G F C C P
Sbjct: 1414 LACENGECVNTEGSFHCFCSP 1434



 Score = 49.6 bits (113), Expect = 9e-06
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +2

Query: 263  CPPGYTGRNCE-TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEE 439
            C  GY G++    DV+EC     C +G +C +   ++ C C   GY     E    + +E
Sbjct: 876  CEEGYRGQSGSCVDVNECLTPGVCAHG-KCTNLEGSFRCSCEQ-GYEVTSDEKGCQDVDE 933

Query: 440  --DRALCGHGVCYDTYGGFVC-ACQ 505
               RA C  G+C +T G F C AC+
Sbjct: 934  CASRASCPTGLCLNTEGSFACSACE 958



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
 Frame = +2

Query: 302 VDECSGAAACLNG-GRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRALCGHGV 466
           +D C+  A  + G G CV+  + Y C C + GY    + A C T+ NEC  D    G G 
Sbjct: 724 IDRCAAGATNVCGPGTCVNLPDGYRCVC-SPGYQLHPSQAYC-TDDNECLRDPCK-GKGR 780

Query: 467 CYDTYGGFVCACQP----ATPGST 526
           C +  G + C C P    AT G+T
Sbjct: 781 CINRVGSYSCFCYPGYTLATSGAT 804



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
 Frame = +3

Query: 60  DPCASAA---CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSC 227
           D CA+ A   C  G  CV    G Y C C PGY     +   + D  C+  PC+  G C
Sbjct: 725 DRCAAGATNVCGPGT-CVNLPDG-YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRC 781



 Score = 32.7 bits (71), Expect = 1.1
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDP--CASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C+  Y  +  +    D   C    C+   RC+ +  G YSC C PGY
Sbjct: 747 YRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI-NRVGSYSCFCYPGY 796


>X81479-1|CAA57232.1|  886|Homo sapiens EMR1 protein.
          Length = 886

 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
 Frame = +2

Query: 269 PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT-GARCETNVNECEEDR 445
           PG  G    TD++EC  +  C     CV+++ +Y+C C     +  + CE +VNEC + R
Sbjct: 122 PGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQVGFISRNSTCE-DVNECADPR 180

Query: 446 ALCGHGVCYDTYGGFVCACQPATPGST 526
           A   H  C +T G + C C P    S+
Sbjct: 181 ACPEHATCNNTVGNYSCFCNPGFESSS 207



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 22/105 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET----------DVDECSGA-------AACLN-GGR----CVDAVNNY 370
           CTC  G+   N +           D+DECS +       ++C N  GR    C+D  ++ 
Sbjct: 56  CTCKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSP 115

Query: 371 TCDCTATGYTGARCETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
           T +    G  G    T++NEC   R    H  C ++ G + C+CQ
Sbjct: 116 TGNDWVPGKPGNFSCTDINECLTSRVCPEHSDCVNSMGSYSCSCQ 160



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YCE 167
           Y C C   +   N   +  + CA   AC   A C  +  G+YSC C PG+  +     C+
Sbjct: 155 YSCSCQVGFISRNSTCEDVNECADPRACPEHATC-NNTVGNYSCFCNPGFESSSGHLSCQ 213

Query: 168 -LEVSLDPL--CVAGPCRNNGSCSVPPG 242
            L+ S + +  C    C  N +C+  PG
Sbjct: 214 GLKASCEDIDECTE-MCPINSTCTNTPG 240



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 8/83 (9%)
 Frame = +3

Query: 33  GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE-LEVSLDPLCVA- 200
           GN    D  +   S  C   + CV +  G YSC C  G+    + CE +    DP     
Sbjct: 126 GNFSCTDINECLTSRVCPEHSDCV-NSMGSYSCSCQVGFISRNSTCEDVNECADPRACPE 184

Query: 201 -GPCRN---NGSCSVPPGGDTYS 257
              C N   N SC   PG ++ S
Sbjct: 185 HATCNNTVGNYSCFCNPGFESSS 207


>DQ217942-1|ABB70739.1|  886|Homo sapiens EGF-like module containing
           mucin-like hormone receptor-like 1 protein.
          Length = 886

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
 Frame = +2

Query: 269 PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGARCETNVNECEED 442
           PG  G    TD++EC  ++ C     CV+++ +Y+C C   G+    + CE +V+EC + 
Sbjct: 122 PGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSC-QVGFISRNSTCE-DVDECADP 179

Query: 443 RALCGHGVCYDTYGGFVCACQPATPGST 526
           RA   H  C +T G + C C P    S+
Sbjct: 180 RACPEHATCNNTVGNYSCFCNPGFESSS 207



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGY-----HGTYC 164
           Y C C   +   N   +  D CA   AC   A C  +  G+YSC C PG+     H ++ 
Sbjct: 155 YSCSCQVGFISRNSTCEDVDECADPRACPEHATC-NNTVGNYSCFCNPGFESSSGHLSFQ 213

Query: 165 ELEVSLDPL--CVAGPCRNNGSCSVPPG 242
            L+ S + +  C    C  N +C+  PG
Sbjct: 214 GLKASCEDIDECTE-MCPINSTCTNTPG 240



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
 Frame = +2

Query: 281 GRNCETDVDECSGA-------AACLN-GGR----CVDAVNNYTCDCTATGYTGARCETNV 424
           G  C+ D+DECS +       ++C N  GR    C+D  ++ T +    G  G    T++
Sbjct: 75  GVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQ 505
           NEC        H  C ++ G + C+CQ
Sbjct: 134 NECLTSSVCPEHSDCVNSMGSYSCSCQ 160



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 11/55 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET----------DVDEC-SGAAACLNGGRCVDAVNNYTCDCTA 388
           CTC PG+   N +           D+DEC    + C     C +A+ +Y+C C A
Sbjct: 244 CTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIA 298



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 8/83 (9%)
 Frame = +3

Query: 33  GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE-LEVSLDPLCVA- 200
           GN    D  +   S+ C   + CV +  G YSC C  G+    + CE ++   DP     
Sbjct: 126 GNFSCTDINECLTSSVCPEHSDCV-NSMGSYSCSCQVGFISRNSTCEDVDECADPRACPE 184

Query: 201 -GPCRN---NGSCSVPPGGDTYS 257
              C N   N SC   PG ++ S
Sbjct: 185 HATCNNTVGNYSCFCNPGFESSS 207


>BC059395-1|AAH59395.1|  821|Homo sapiens EMR1 protein protein.
          Length = 821

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
 Frame = +2

Query: 269 PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGARCETNVNECEED 442
           PG  G    TD++EC  ++ C     CV+++ +Y+C C   G+    + CE +V+EC + 
Sbjct: 122 PGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSC-QVGFISRNSTCE-DVDECADP 179

Query: 443 RALCGHGVCYDTYGGFVCACQPATPGST 526
           RA   H  C +T G + C C P    S+
Sbjct: 180 RACPEHATCNNTVGNYSCFCNPGFESSS 207



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGY-----HGTYC 164
           Y C C   +   N   +  D CA   AC   A C  +  G+YSC C PG+     H ++ 
Sbjct: 155 YSCSCQVGFISRNSTCEDVDECADPRACPEHATC-NNTVGNYSCFCNPGFESSSGHLSFQ 213

Query: 165 ELEVSLDPL--CVAGPCRNNGSCSVPPG 242
            L+ S + +  C    C  N +C+  PG
Sbjct: 214 GLKASCEDIDECTE-MCPINSTCTNTPG 240



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
 Frame = +2

Query: 281 GRNCETDVDECSGA-------AACLN-GGR----CVDAVNNYTCDCTATGYTGARCETNV 424
           G  C+ D+DECS +       ++C N  GR    C+D  ++ T +    G  G    T++
Sbjct: 75  GVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQ 505
           NEC        H  C ++ G + C+CQ
Sbjct: 134 NECLTSSVCPEHSDCVNSMGSYSCSCQ 160



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 11/55 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET----------DVDEC-SGAAACLNGGRCVDAVNNYTCDCTA 388
           CTC PG+   N +           D+DEC    + C     C +A+ +Y+C C A
Sbjct: 244 CTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIA 298



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 8/83 (9%)
 Frame = +3

Query: 33  GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE-LEVSLDPLCVA- 200
           GN    D  +   S+ C   + CV +  G YSC C  G+    + CE ++   DP     
Sbjct: 126 GNFSCTDINECLTSSVCPEHSDCV-NSMGSYSCSCQVGFISRNSTCEDVDECADPRACPE 184

Query: 201 -GPCRN---NGSCSVPPGGDTYS 257
              C N   N SC   PG ++ S
Sbjct: 185 HATCNNTVGNYSCFCNPGFESSS 207


>AB065918-1|BAC06133.1|  929|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 929

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
 Frame = +2

Query: 269 PGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY--TGARCETNVNECEED 442
           PG  G    TD++EC  ++ C     CV+++ +Y+C C   G+    + CE +V+EC + 
Sbjct: 140 PGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSC-QVGFISRNSTCE-DVDECADP 197

Query: 443 RALCGHGVCYDTYGGFVCACQPATPGST 526
           RA   H  C +T G + C C P    S+
Sbjct: 198 RACPEHATCNNTVGNYSCFCNPGFESSS 225



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGY-----HGTYC 164
           Y C C   +   N   +  D CA   AC   A C  +  G+YSC C PG+     H ++ 
Sbjct: 173 YSCSCQVGFISRNSTCEDVDECADPRACPEHATC-NNTVGNYSCFCNPGFESSSGHLSFQ 231

Query: 165 ELEVSLDPL--CVAGPCRNNGSCSVPPG 242
            L+ S + +  C    C  N +C+  PG
Sbjct: 232 GLKASCEDIDECTE-MCPINSTCTNTPG 258



 Score = 37.1 bits (82), Expect = 0.052
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
 Frame = +2

Query: 281 GRNCETDVDECSGA-------AACLN-GGR----CVDAVNNYTCDCTATGYTGARCETNV 424
           G  C+ D+DECS +       ++C N  GR    C+D  ++ T +    G  G    T++
Sbjct: 93  GVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 151

Query: 425 NECEEDRALCGHGVCYDTYGGFVCACQ 505
           NEC        H  C ++ G + C+CQ
Sbjct: 152 NECLTSSVCPEHSDCVNSMGSYSCSCQ 178



 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 11/55 (20%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET----------DVDEC-SGAAACLNGGRCVDAVNNYTCDCTA 388
           CTC PG+   N +           D+DEC    + C     C +A+ +Y+C C A
Sbjct: 262 CTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIA 316



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 8/83 (9%)
 Frame = +3

Query: 33  GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY--HGTYCE-LEVSLDPLCVA- 200
           GN    D  +   S+ C   + CV +  G YSC C  G+    + CE ++   DP     
Sbjct: 144 GNFSCTDINECLTSSVCPEHSDCV-NSMGSYSCSCQVGFISRNSTCEDVDECADPRACPE 202

Query: 201 -GPCRN---NGSCSVPPGGDTYS 257
              C N   N SC   PG ++ S
Sbjct: 203 HATCNNTVGNYSCFCNPGFESSS 225


>AB024578-1|BAA88952.1|   78|Homo sapiens notch4 protein.
          Length = 78

 Score = 60.9 bits (141), Expect = 4e-09
 Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
 Frame = +2

Query: 287 NCETDVDECS--GAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNECEEDRALCGH 460
           +C  DVD+C   G   C NGG C ++  ++ C C  +G+ G  CE N+++C    A C  
Sbjct: 2   DCSEDVDQCEAQGPPHCRNGGTCQNSAGSFHCVC-VSGWGGTSCEENLDDC--IAATCAP 58

Query: 461 G-VCYDTYGGFVCACQP 508
           G  C D  G F C C P
Sbjct: 59  GSTCIDRVGSFSCLCPP 75



 Score = 46.4 bits (105), Expect = 9e-05
 Identities = 17/42 (40%), Positives = 26/42 (61%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           C C  G+ G +CE ++D+C  AA C  G  C+D V +++C C
Sbjct: 33  CVCVSGWGGTSCEENLDDCI-AATCAPGSTCIDRVGSFSCLC 73



 Score = 46.0 bits (104), Expect = 1e-04
 Identities = 19/48 (39%), Positives = 28/48 (58%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPG 146
           + C C + + G +CE +  D C +A C  G+ C+ D  G +SC CPPG
Sbjct: 31  FHCVCVSGWGGTSCEENLDD-CIAATCAPGSTCI-DRVGSFSCLCPPG 76



 Score = 38.7 bits (86), Expect = 0.017
 Identities = 20/61 (32%), Positives = 30/61 (49%)
 Frame = +3

Query: 45  EVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGS 224
           +VD  +      CR+G  C ++  G + C C  G+ GT C  E +LD  C+A  C    +
Sbjct: 6   DVDQCEAQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSC--EENLDD-CIAATCAPGST 61

Query: 225 C 227
           C
Sbjct: 62  C 62


>BC053656-1|AAH53656.1|  470|Homo sapiens EDIL3 protein protein.
          Length = 470

 Score = 60.1 bits (139), Expect = 6e-09
 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
 Frame = +2

Query: 257 CTCPPGYTGRNCET--DVDECSGAAACLNGGRCV-------DAVNNYTCDCTATGYTGAR 409
           C CP G+T  NC +  +V  C+    C NGG C        D    Y C C   G+ G  
Sbjct: 48  CECPDGFTDPNCSSVVEVGPCT-PNPCHNGGTCEISEAYRGDTFIGYVCKCPR-GFNGIH 105

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           C+ N+NECE +    G G+C D    + C C
Sbjct: 106 CQHNINECEVEPCKNG-GICTDLVANYSCEC 135



 Score = 55.6 bits (128), Expect = 1e-07
 Identities = 21/54 (38%), Positives = 32/54 (59%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE 415
           +C CP G+ G +C+ +++EC     C NGG C D V NY+C+C    + G  C+
Sbjct: 94  VCKCPRGFNGIHCQHNINECE-VEPCKNGGICTDLVANYSCECPGE-FMGRNCQ 145



 Score = 54.8 bits (126), Expect = 2e-07
 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
 Frame = +3

Query: 3   YECHCTARYTGNNCE--VDAGDPCASAACRHGARCV--EDGRGD----YSCDCPPGYHGT 158
           + C C   +T  NC   V+ G PC    C +G  C   E  RGD    Y C CP G++G 
Sbjct: 46  FSCECPDGFTDPNCSSVVEVG-PCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGI 104

Query: 159 YCELEVSLDPLCVAGPCRNNGSCS 230
           +C+  ++    C   PC+N G C+
Sbjct: 105 HCQHNIN---ECEVEPCKNGGICT 125



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +3

Query: 57  GDPCASAACRHGARCVED-GRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSV 233
           GD C    C +G  C+     G +SC+CP G+    C   V + P C   PC N G+C +
Sbjct: 23  GDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVGP-CTPNPCHNGGTCEI 81

Query: 234 PPG--GDTY 254
                GDT+
Sbjct: 82  SEAYRGDTF 90



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 22/72 (30%), Positives = 36/72 (50%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSL 182
           Y C C   + G +C+ +  + C    C++G  C  D   +YSC+CP  + G  C+ + S 
Sbjct: 93  YVCKCPRGFNGIHCQHNINE-CEVEPCKNGGICT-DLVANYSCECPGEFMGRNCQYKCS- 149

Query: 183 DPLCVAGPCRNN 218
            PL + G   +N
Sbjct: 150 GPLGIEGGIISN 161


>U89336-6|AAB47494.1|  293|Homo sapiens NG3 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>BX284686-12|CAM26220.1|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>BC052591-1|AAH52591.1|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>BC035574-1|AAH35574.1|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>AY358139-1|AAQ88506.1|  293|Homo sapiens NG3 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>AL845464-11|CAI41800.2|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>AL662884-17|CAI18345.2|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>AL662828-17|CAI17428.1|  293|Homo sapiens EGF-like-domain, multiple
           8 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVKREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>AB190520-1|BAD51398.1|  293|Homo sapiens VE-statin2 protein.
          Length = 293

 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 34/95 (35%), Positives = 48/95 (50%)
 Frame = +2

Query: 218 RQLQRAPRRRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY 397
           R+++R  ++ H +C C  G+  R+      E   A  CLNGG CV       C+C A G+
Sbjct: 83  REVRREVQQTHAVC-CQ-GWKKRHPGALTCEAICAKPCLNGGVCVRPDQ---CEC-APGW 136

Query: 398 TGARCETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            G  C  +V+EC     LC H  C++T G F C C
Sbjct: 137 GGKHCHVDVDECRTSITLCSHH-CFNTAGSFTCGC 170



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 13/45 (28%), Positives = 20/45 (44%)
 Frame = +3

Query: 6   ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCP 140
           +C C   + G +C VD  D C ++       C     G ++C CP
Sbjct: 129 QCECAPGWGGKHCHVDV-DECRTSITLCSHHCFNTA-GSFTCGCP 171


>X12892-1|CAA31383.1|  650|Homo sapiens protein ( H.sapiens mRNA for
           protein S. ).
          Length = 650

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 117 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 174

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 175 DVDECSLKPSICGTAVCKNILGDFECEC 202



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 93  DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 150

Query: 231 VPPG 242
             PG
Sbjct: 151 NTPG 154



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 115 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 173

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 174 KDVDECSLKPSICGTAVCKNILGDFECECPEG 205



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 156 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206


>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
          Length = 1394

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            CTC  GY        CE D+DEC     C +G +C +   ++ C C   GY     G  C
Sbjct: 776  CTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG-QCRNTEGSFQCVCDQ-GYRASGLGDHC 832

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            E ++NEC ED+++C  G C +T G + C C
Sbjct: 833  E-DINECLEDKSVCQRGDCINTAGSYDCTC 861



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G++    GR CE D+DEC     C + G C +   ++ C C         G  C 
Sbjct: 900  CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 957

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             +VNECE    +CG   C +  G F+C C
Sbjct: 958  VDVNECELLSGVCGEAFCENVEGSFLCVC 986



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY     G +CE D++EC    +    G C++   +Y C C   G+       C+
Sbjct: 817  CVCDQGYRASGLGDHCE-DINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQ 874

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
             ++NECE    LCG  G C +T G F C CQ
Sbjct: 875  -DINECEHP-GLCGPQGECLNTEGSFHCVCQ 903



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA----RCETNVN 427
           C  G+ G N +  DVDEC     C NG  C +   +Y C C   GYT       C  +++
Sbjct: 698 CTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK-GYTRTPDHKHCR-DID 754

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC++   LC +G C +T G F C C
Sbjct: 755 ECQQGN-LCVNGQCKNTEGSFRCTC 778



 Score = 50.8 bits (116), Expect = 4e-06
 Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE---DRALC 454
            E   +EC     C NG RCV     YTCDC   GY   T      +VNEC+E     +LC
Sbjct: 1292 ELQAEECGILNGCENG-RCVRVQEGYTCDC-LDGYHLDTAKMTCFDVNECDELNNRMSLC 1349

Query: 455  GHGVCYDTYGGFVCACQP 508
             +  C +T G + C C P
Sbjct: 1350 KNAKCINTDGSYKCLCLP 1367



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARC 412
           LC CP G+     G NC  DVDEC     C   G CV+ V  + C+   +GY      RC
Sbjct: 612 LCICPAGFMASEEGTNC-IDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQRGRC 669

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E +++EC  + + C    C ++ G + C   P T G
Sbjct: 670 E-DIDEC-LNPSTCPDEQCVNSPGSYQCV--PCTEG 701



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---TNVNECEEDRALCGHGV 466
           T+++EC+        G C++    YTC C   GY  +  +    +++EC + + LC  G 
Sbjct: 545 TEINECTVNPDICGAGHCINLPVRYTCICYE-GYRFSEQQRKCVDIDECTQVQHLCSQGR 603

Query: 467 CYDTYGGFVCAC 502
           C +T G F+C C
Sbjct: 604 CENTEGSFLCIC 615



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
           C C  GY      R C  D+DEC+      + GRC +   ++ C C A G+  +   TN 
Sbjct: 571 CICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGRCENTEGSFLCICPA-GFMASEEGTNC 628

Query: 422 --VNECEEDRALCGHGVCYDTYGGFVC 496
             V+EC     +CG G C +T G F C
Sbjct: 629 IDVDECLRP-DVCGEGHCVNTVGAFRC 654



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = +2

Query: 299  DVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATGYTGARCET-NVNECEEDRALCGHGV 466
            D DEC   G   C NG  C++    Y C C   T Y   + +  +++EC+ D + C  G 
Sbjct: 1097 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ 1154

Query: 467  CYDTYGGFVCAC 502
            C +T G + C C
Sbjct: 1155 CVNTEGSYNCFC 1166



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT 385
            D+DEC   ++C++G +CV+   +Y C CT
Sbjct: 1140 DMDECQDPSSCIDG-QCVNTEGSYNCFCT 1167



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
 Frame = +2

Query: 263 CPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           C PGY   N   C+ D++EC     C NG  C++ + +Y C C
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTC 326



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YEC-HCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YC 164
           Y+C  CT  + G N +    D C     C +G  C  +  G Y C C  GY  T    +C
Sbjct: 693 YQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-C-SNLEGSYMCSCHKGYTRTPDHKHC 750

Query: 165 E--LEVSLDPLCVAGPCRN 215
               E     LCV G C+N
Sbjct: 751 RDIDECQQGNLCVNGQCKN 769



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC+  + +C +G C +T G + C C+    P  T + C
Sbjct: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339


>M14338-1|AAA60181.1|  650|Homo sapiens protein S precursor protein.
          Length = 650

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 117 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 174

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 175 DVDECSLKPSICGTAVCKNILGDFECEC 202



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 93  DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 150

Query: 231 VPPG 242
             PG
Sbjct: 151 NTPG 154



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 115 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 173

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 174 KDVDECSLKPSICGTAVCKNILGDFECECPEG 205



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 156 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGY 206


>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
            factor beta binding protein 1 protein.
          Length = 1395

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            CTC  GY        CE D+DEC     C +G +C +   ++ C C   GY     G  C
Sbjct: 777  CTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG-QCRNTEGSFQCVCDQ-GYRASGLGDHC 833

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            E ++NEC ED+++C  G C +T G + C C
Sbjct: 834  E-DINECLEDKSVCQRGDCINTAGSYDCTC 862



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G++    GR CE D+DEC     C + G C +   ++ C C         G  C 
Sbjct: 901  CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 958

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             +VNECE    +CG   C +  G F+C C
Sbjct: 959  VDVNECELLSGVCGEAFCENVEGSFLCVC 987



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY     G +CE D++EC    +    G C++   +Y C C   G+       C+
Sbjct: 818  CVCDQGYRASGLGDHCE-DINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQ 875

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
             ++NECE    LCG  G C +T G F C CQ
Sbjct: 876  -DINECEHP-GLCGPQGECLNTEGSFHCVCQ 904



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA----RCETNVN 427
           C  G+ G N +  DVDEC     C NG  C +   +Y C C   GYT       C  +++
Sbjct: 699 CTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK-GYTRTPDHKHCR-DID 755

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC++   LC +G C +T G F C C
Sbjct: 756 ECQQGN-LCVNGQCKNTEGSFRCTC 779



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE---DRALC 454
            E   +EC     C NG RCV     YTCDC   GY   T      +VNEC+E     +LC
Sbjct: 1293 ELQAEECGILNGCENG-RCVRVQEGYTCDC-FDGYHLDTAKMTCVDVNECDELNNRMSLC 1350

Query: 455  GHGVCYDTYGGFVCACQP 508
             +  C +T G + C C P
Sbjct: 1351 KNAKCINTDGSYKCLCLP 1368



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARC 412
           LC CP G+     G NC  DVDEC     C   G CV+ V  + C+   +GY      RC
Sbjct: 613 LCICPAGFMASEEGTNC-IDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQRGRC 670

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E +++EC  + + C    C ++ G + C   P T G
Sbjct: 671 E-DIDEC-LNPSTCPDEQCVNSPGSYQCV--PCTEG 702



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---TNVNECEEDRALCGHGV 466
           T+++EC+        G C++    YTC C   GY  +  +    +++EC + + LC  G 
Sbjct: 546 TEINECTVNPDICGAGHCINLPVRYTCICYE-GYRFSEQQRKCVDIDECTQVQHLCSQGR 604

Query: 467 CYDTYGGFVCAC 502
           C +T G F+C C
Sbjct: 605 CENTEGSFLCIC 616



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
           C C  GY      R C  D+DEC+      + GRC +   ++ C C A G+  +   TN 
Sbjct: 572 CICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGRCENTEGSFLCICPA-GFMASEEGTNC 629

Query: 422 --VNECEEDRALCGHGVCYDTYGGFVC 496
             V+EC     +CG G C +T G F C
Sbjct: 630 IDVDECLRP-DVCGEGHCVNTVGAFRC 655



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = +2

Query: 299  DVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATGYTGARCET-NVNECEEDRALCGHGV 466
            D DEC   G   C NG  C++    Y C C   T Y   + +  +++EC+ D + C  G 
Sbjct: 1098 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ 1155

Query: 467  CYDTYGGFVCAC 502
            C +T G + C C
Sbjct: 1156 CVNTEGSYNCFC 1167



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT 385
            D+DEC   ++C++G +CV+   +Y C CT
Sbjct: 1141 DMDECQDPSSCIDG-QCVNTEGSYNCFCT 1168



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
 Frame = +2

Query: 263 CPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           C PGY   N   C+ D++EC     C NG  C++ + +Y C C
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTC 326



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YEC-HCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YC 164
           Y+C  CT  + G N +    D C     C +G  C  +  G Y C C  GY  T    +C
Sbjct: 694 YQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-C-SNLEGSYMCSCHKGYTRTPDHKHC 751

Query: 165 E--LEVSLDPLCVAGPCRN 215
               E     LCV G C+N
Sbjct: 752 RDIDECQQGNLCVNGQCKN 770



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC+  + +C +G C +T G + C C+    P  T + C
Sbjct: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339


>BC039143-1|AAH39143.1|  740|Homo sapiens FAT2 protein protein.
          Length = 740

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 25/66 (37%), Positives = 36/66 (54%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPP ++G++CE   + C+  A CL GG C+ +    +C+C    YTG RCE     C
Sbjct: 362 VCKCPPQFSGKHCEQGRENCT-FAPCLEGGTCILSPKGASCNCPHP-YTGDRCEMEARGC 419

Query: 434 EEDRAL 451
            E   L
Sbjct: 420 SEGHCL 425



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C  +++G +CE    + C  A C  G  C+   +G  SC+CP  Y G  CE+E
Sbjct: 361 YVCKCPPQFSGKHCE-QGRENCTFAPCLEGGTCILSPKGA-SCNCPHPYTGDRCEME 415



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C+   C +G +C       Y C CPP + G +CE        C   PC   G+C + P
Sbjct: 340 DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSP 396

Query: 240 GGDTYSAP 263
            G + + P
Sbjct: 397 KGASCNCP 404



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           C    D CS    CLNGG+C       Y C C    ++G  CE     C     L G G 
Sbjct: 335 CCLHSDYCS-QNTCLNGGKCSWTHGAGYVCKCPPQ-FSGKHCEQGRENCTFAPCLEG-GT 391

Query: 467 CYDTYGGFVCAC 502
           C  +  G  C C
Sbjct: 392 CILSPKGASCNC 403


>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
            factor-beta binding protein-1S protein.
          Length = 1394

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257  CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
            CTC  GY        CE D+DEC     C +G +C +   ++ C C   GY     G  C
Sbjct: 776  CTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG-QCRNTEGSFQCVCDQ-GYRASGLGDHC 832

Query: 413  ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            E ++NEC ED+++C  G C +T G + C C
Sbjct: 833  E-DINECLEDKSVCQRGDCINTAGSYDCTC 861



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G++    GR CE D+DEC     C + G C +   ++ C C         G  C 
Sbjct: 900  CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 957

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             +VNECE    +CG   C +  G F+C C
Sbjct: 958  VDVNECELLSGVCGEAFCENVEGSFLCVC 986



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY     G +CE D++EC    +    G C++   +Y C C   G+       C+
Sbjct: 817  CVCDQGYRASGLGDHCE-DINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQ 874

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
             ++NECE    LCG  G C +T G F C CQ
Sbjct: 875  -DINECEHP-GLCGPQGECLNTEGSFHCVCQ 903



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA----RCETNVN 427
           C  G+ G N +  DVDEC     C NG  C +   +Y C C   GYT       C  +++
Sbjct: 698 CTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK-GYTRTPDHKHCR-DID 754

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC++   LC +G C +T G F C C
Sbjct: 755 ECQQGN-LCVNGQCKNTEGSFRCTC 778



 Score = 51.6 bits (118), Expect = 2e-06
 Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE---DRALC 454
            E   +EC     C NG RCV     YTCDC   GY   T      +VNEC+E     +LC
Sbjct: 1292 ELQAEECGILNGCENG-RCVRVQEGYTCDC-LDGYHLDTAKMTCVDVNECDELNNRMSLC 1349

Query: 455  GHGVCYDTYGGFVCACQP 508
             +  C +T G + C C P
Sbjct: 1350 KNAKCINTDGSYKCLCLP 1367



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARC 412
           LC CP G+     G NC  DVDEC     C   G CV+ V  + C+   +GY      RC
Sbjct: 612 LCICPAGFMASEEGTNC-IDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQRGRC 669

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E +++EC  + + C    C ++ G + C   P T G
Sbjct: 670 E-DIDEC-LNPSTCPDEQCVNSPGSYQCV--PCTEG 701



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---TNVNECEEDRALCGHGV 466
           T+++EC+        G C++    YTC C   GY  +  +    +++EC + + LC  G 
Sbjct: 545 TEINECTVNPDICGAGHCINLPVRYTCICYE-GYRFSEQQRKCVDIDECTQVQHLCSQGR 603

Query: 467 CYDTYGGFVCAC 502
           C +T G F+C C
Sbjct: 604 CENTEGSFLCIC 615



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
           C C  GY      R C  D+DEC+      + GRC +   ++ C C A G+  +   TN 
Sbjct: 571 CICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGRCENTEGSFLCICPA-GFMASEEGTNC 628

Query: 422 --VNECEEDRALCGHGVCYDTYGGFVC 496
             V+EC     +CG G C +T G F C
Sbjct: 629 IDVDECLRP-DVCGEGHCVNTVGAFRC 654



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = +2

Query: 299  DVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATGYTGARCET-NVNECEEDRALCGHGV 466
            D DEC   G   C NG  C++    Y C C   T Y   + +  +++EC+ D + C  G 
Sbjct: 1097 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ 1154

Query: 467  CYDTYGGFVCAC 502
            C +T G + C C
Sbjct: 1155 CVNTEGSYNCFC 1166



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT 385
            D+DEC   ++C++G +CV+   +Y C CT
Sbjct: 1140 DMDECQDPSSCIDG-QCVNTEGSYNCFCT 1167



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
 Frame = +2

Query: 263 CPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           C PGY   N   C+ D++EC     C NG  C++ + +Y C C
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTC 326



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YEC-HCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YC 164
           Y+C  CT  + G N +    D C     C +G  C  +  G Y C C  GY  T    +C
Sbjct: 693 YQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-C-SNLEGSYMCSCHKGYTRTPDHKHC 750

Query: 165 E--LEVSLDPLCVAGPCRN 215
               E     LCV G C+N
Sbjct: 751 RDIDECQQGNLCVNGQCKN 769



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC+  + +C +G C +T G + C C+    P  T + C
Sbjct: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 339


>AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 protein.
          Length = 4349

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 25/66 (37%), Positives = 36/66 (54%)
 Frame = +2

Query: 254  LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
            +C CPP ++G++CE   + C+  A CL GG C+ +    +C+C    YTG RCE     C
Sbjct: 3971 VCKCPPQFSGKHCEQGRENCT-FAPCLEGGTCILSPKGASCNCPHP-YTGDRCEMEARGC 4028

Query: 434  EEDRAL 451
             E   L
Sbjct: 4029 SEGHCL 4034



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +3

Query: 3    YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
            Y C C  +++G +CE    + C  A C  G  C+   +G  SC+CP  Y G  CE+E
Sbjct: 3970 YVCKCPPQFSGKHCE-QGRENCTFAPCLEGGTCILSPKGA-SCNCPHPYTGDRCEME 4024



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
            D C+   C +G +C       Y C CPP + G +CE        C   PC   G+C + P
Sbjct: 3949 DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSP 4005

Query: 240  GGDTYSAP 263
             G + + P
Sbjct: 4006 KGASCNCP 4013



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +2

Query: 290  CETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
            C    D CS    CLNGG+C       Y C C    ++G  CE     C     L G G 
Sbjct: 3944 CCLHSDYCS-QNTCLNGGKCSWTHGAGYVCKCPPQ-FSGKHCEQGRENCTFAPCLEG-GT 4000

Query: 467  CYDTYGGFVCAC 502
            C  +  G  C C
Sbjct: 4001 CILSPKGASCNC 4012


>AC019127-1|AAY24260.1|  697|Homo sapiens unknown protein.
          Length = 697

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
           CTC  GY        CE D+DEC     C +G +C +   ++ C C   GY     G  C
Sbjct: 230 CTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG-QCRNTEGSFQCVCDQ-GYRASGLGDHC 286

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           E ++NEC ED+++C  G C +T G + C C
Sbjct: 287 E-DINECLEDKSVCQRGDCINTAGSYDCTC 315



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
           C C  G++    GR CE D+DEC     C + G C +   ++ C C         G  C 
Sbjct: 354 CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 411

Query: 416 TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
            +VNECE    +CG   C +  G F+C C
Sbjct: 412 VDVNECELLSGVCGEAFCENVEGSFLCVC 440



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
           C C  GY     G +CE D++EC    +    G C++   +Y C C   G+       C+
Sbjct: 271 CVCDQGYRASGLGDHCE-DINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQ 328

Query: 416 TNVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
            ++NECE    LCG  G C +T G F C CQ
Sbjct: 329 -DINECEHP-GLCGPQGECLNTEGSFHCVCQ 357



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA----RCETNVN 427
           C  G+ G N +  DVDEC     C NG  C +   +Y C C   GYT       C  +++
Sbjct: 152 CTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK-GYTRTPDHKHCR-DID 208

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC++   LC +G C +T G F C C
Sbjct: 209 ECQQGN-LCVNGQCKNTEGSFRCTC 232



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARC 412
           LC CP G+     G NC  DVDEC     C   G CV+ V  + C+   +GY      RC
Sbjct: 66  LCICPAGFMASEEGTNC-IDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQRGRC 123

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E +++EC  + + C    C ++ G + C   P T G
Sbjct: 124 E-DIDEC-LNPSTCPDEQCVNSPGSYQCV--PCTEG 155



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
           C C  GY      R C  D+DEC+      + GRC +   ++ C C A G+  +   TN 
Sbjct: 25  CICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGRCENTEGSFLCICPA-GFMASEEGTNC 82

Query: 422 --VNECEEDRALCGHGVCYDTYGGFVC 496
             V+EC     +CG G C +T G F C
Sbjct: 83  IDVDECLRP-DVCGEGHCVNTVGAFRC 108



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
 Frame = +2

Query: 302 VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---TNVNECEEDRALCGHGVCY 472
           ++EC+        G C++    YTC C   GY  +  +    +++EC + + LC  G C 
Sbjct: 1   INECTVNPDICGAGHCINLPVRYTCICYE-GYRFSEQQRKCVDIDECTQVQHLCSQGRCE 59

Query: 473 DTYGGFVCAC 502
           +T G F+C C
Sbjct: 60  NTEGSFLCIC 69



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = +2

Query: 299 DVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATGYTGARCET-NVNECEEDRALCGHGV 466
           D DEC   G   C NG  C++    Y C C   T Y   + +  +++EC+ D + C  G 
Sbjct: 551 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ 608

Query: 467 CYDTYGGFVCAC 502
           C +T G + C C
Sbjct: 609 CVNTEGSYNCFC 620



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +2

Query: 299 DVDECSGAAACLNGGRCVDAVNNYTCDCT 385
           D+DEC   ++C++G +CV+   +Y C CT
Sbjct: 594 DMDECQDPSSCIDG-QCVNTEGSYNCFCT 621



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YEC-HCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YC 164
           Y+C  CT  + G N +    D C     C +G  C  +  G Y C C  GY  T    +C
Sbjct: 147 YQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-C-SNLEGSYMCSCHKGYTRTPDHKHC 204

Query: 165 E--LEVSLDPLCVAGPCRN 215
               E     LCV G C+N
Sbjct: 205 RDIDECQQGNLCVNGQCKN 223


>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
           factor beta binding protein 1 isoform LTBP-1S varian
           protein.
          Length = 1348

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
 Frame = +2

Query: 257 CTCPPGY----TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT----GARC 412
           CTC  GY        CE D+DEC     C +G +C +   ++ C C   GY     G  C
Sbjct: 730 CTCGQGYQLSAAKDQCE-DIDECQHRHLCAHG-QCRNTEGSFQCVCDQ-GYRASGLGDHC 786

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCAC 502
           E ++NEC ED+++C  G C +T G + C C
Sbjct: 787 E-DINECLEDKSVCQRGDCINTAGSYDCTC 815



 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTA---TGYTGARCE 415
            C C  G++    GR CE D+DEC     C + G C +   ++ C C         G  C 
Sbjct: 854  CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC- 911

Query: 416  TNVNECEEDRALCGHGVCYDTYGGFVCAC 502
             +VNECE    +CG   C +  G F+C C
Sbjct: 912  VDVNECELLSGVCGEAFCENVEGSFLCVC 940



 Score = 54.4 bits (125), Expect = 3e-07
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257  CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT---GARCE 415
            C C  GY     G +CE D++EC    +    G C++   +Y C C   G+       C+
Sbjct: 771  CVCDQGYRASGLGDHCE-DINECLEDKSVCQRGDCINTAGSYDCTCP-DGFQLDDNKTCQ 828

Query: 416  TNVNECEEDRALCG-HGVCYDTYGGFVCACQ 505
             ++NECE    LCG  G C +T G F C CQ
Sbjct: 829  -DINECEHP-GLCGPQGECLNTEGSFHCVCQ 857



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 31/85 (36%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
 Frame = +2

Query: 263 CPPGYTGRNCET-DVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGA----RCETNVN 427
           C  G+ G N +  DVDEC     C NG  C +   +Y C C   GYT       C  +++
Sbjct: 652 CTEGFRGWNGQCLDVDECLEPNVCANGD-CSNLEGSYMCSCHK-GYTRTPDHKHCR-DID 708

Query: 428 ECEEDRALCGHGVCYDTYGGFVCAC 502
           EC++   LC +G C +T G F C C
Sbjct: 709 ECQQGN-LCVNGQCKNTEGSFRCTC 732



 Score = 51.2 bits (117), Expect = 3e-06
 Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
 Frame = +2

Query: 293  ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARCETNVNECEE---DRALC 454
            E   +EC     C NG RCV     YTCDC   GY   T      +VNEC+E     +LC
Sbjct: 1246 ELQAEECGILNGCENG-RCVRVQEGYTCDC-FDGYHLDTAKMTCVDVNECDELNNRMSLC 1303

Query: 455  GHGVCYDTYGGFVCACQP 508
             +  C +T G + C C P
Sbjct: 1304 KNAKCINTDGSYKCLCLP 1321



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
 Frame = +2

Query: 254 LCTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY---TGARC 412
           LC CP G+     G NC  DVDEC     C   G CV+ V  + C+   +GY      RC
Sbjct: 566 LCICPAGFMASEEGTNC-IDVDECLRPDVC-GEGHCVNTVGAFRCEYCDSGYRMTQRGRC 623

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQPATPG 520
           E +++EC  + + C    C ++ G + C   P T G
Sbjct: 624 E-DIDEC-LNPSTCPDEQCVNSPGSYQCV--PCTEG 655



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
 Frame = +2

Query: 296 TDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCE---TNVNECEEDRALCGHGV 466
           T+++EC+        G C++    YTC C   GY  +  +    +++EC + + LC  G 
Sbjct: 499 TEINECTVNPDICGAGHCINLPVRYTCICYE-GYRFSEQQRKCVDIDECTQVQHLCSQGR 557

Query: 467 CYDTYGGFVCAC 502
           C +T G F+C C
Sbjct: 558 CENTEGSFLCIC 569



 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN- 421
           C C  GY      R C  D+DEC+      + GRC +   ++ C C A G+  +   TN 
Sbjct: 525 CICYEGYRFSEQQRKC-VDIDECTQVQHLCSQGRCENTEGSFLCICPA-GFMASEEGTNC 582

Query: 422 --VNECEEDRALCGHGVCYDTYGGFVC 496
             V+EC     +CG G C +T G F C
Sbjct: 583 IDVDECLRP-DVCGEGHCVNTVGAFRC 608



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
 Frame = +2

Query: 299  DVDECS--GAAACLNGGRCVDAVNNYTCDCT-ATGYTGARCET-NVNECEEDRALCGHGV 466
            D DEC   G   C NG  C++    Y C C   T Y   + +  +++EC+ D + C  G 
Sbjct: 1051 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQ-DPSSCIDGQ 1108

Query: 467  CYDTYGGFVCAC 502
            C +T G + C C
Sbjct: 1109 CVNTEGSYNCFC 1120



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 12/29 (41%), Positives = 20/29 (68%)
 Frame = +2

Query: 299  DVDECSGAAACLNGGRCVDAVNNYTCDCT 385
            D+DEC   ++C++G +CV+   +Y C CT
Sbjct: 1094 DMDECQDPSSCIDG-QCVNTEGSYNCFCT 1121



 Score = 33.5 bits (73), Expect = 0.64
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
 Frame = +2

Query: 263 CPPGYTGRN---CETDVDECSGAAACLNGGRCVDAVNNYTCDC 382
           C PGY   N   C+ D++EC     C NG  C++ + +Y C C
Sbjct: 292 CLPGYKRVNNTFCQ-DINECQLQGVCPNG-ECLNTMGSYRCTC 332



 Score = 31.1 bits (67), Expect = 3.4
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
 Frame = +3

Query: 3   YEC-HCTARYTGNNCEVDAGDPCASA-ACRHGARCVEDGRGDYSCDCPPGYHGT----YC 164
           Y+C  CT  + G N +    D C     C +G  C  +  G Y C C  GY  T    +C
Sbjct: 647 YQCVPCTEGFRGWNGQCLDVDECLEPNVCANGD-C-SNLEGSYMCSCHKGYTRTPDHKHC 704

Query: 165 E--LEVSLDPLCVAGPCRN 215
               E     LCV G C+N
Sbjct: 705 RDIDECQQGNLCVNGQCKN 723



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
 Frame = +2

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQPA-TPGSTATGC 538
           ++NEC+  + +C +G C +T G + C C+    P  T + C
Sbjct: 306 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSC 345


>AB177851-1|BAD66829.1|  573|Homo sapiens KIAA0811 splice variant 1
           protein.
          Length = 573

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 25/66 (37%), Positives = 36/66 (54%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPP ++G++CE   + C+  A CL GG C+ +    +C+C    YTG RCE     C
Sbjct: 195 VCKCPPQFSGKHCEQGRENCT-FAPCLEGGTCILSPKGASCNCPHP-YTGDRCEMEARGC 252

Query: 434 EEDRAL 451
            E   L
Sbjct: 253 SEGHCL 258



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C  +++G +CE    + C  A C  G  C+   +G  SC+CP  Y G  CE+E
Sbjct: 194 YVCKCPPQFSGKHCE-QGRENCTFAPCLEGGTCILSPKGA-SCNCPHPYTGDRCEME 248



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C+   C +G +C       Y C CPP + G +CE        C   PC   G+C + P
Sbjct: 173 DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSP 229

Query: 240 GGDTYSAP 263
            G + + P
Sbjct: 230 KGASCNCP 237



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           C    D CS    CLNGG+C       Y C C    ++G  CE     C     L G G 
Sbjct: 168 CCLHSDYCS-QNTCLNGGKCSWTHGAGYVCKCPPQ-FSGKHCEQGRENCTFAPCLEG-GT 224

Query: 467 CYDTYGGFVCAC 502
           C  +  G  C C
Sbjct: 225 CILSPKGASCNC 236


>AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein.
          Length = 1123

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 25/66 (37%), Positives = 36/66 (54%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPP ++G++CE   + C+  A CL GG C+ +    +C+C    YTG RCE     C
Sbjct: 745 VCKCPPQFSGKHCEQGRENCT-FAPCLEGGTCILSPKGASCNCPHP-YTGDRCEMEARGC 802

Query: 434 EEDRAL 451
            E   L
Sbjct: 803 SEGHCL 808



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C  +++G +CE    + C  A C  G  C+   +G  SC+CP  Y G  CE+E
Sbjct: 744 YVCKCPPQFSGKHCE-QGRENCTFAPCLEGGTCILSPKGA-SCNCPHPYTGDRCEME 798



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C+   C +G +C       Y C CPP + G +CE        C   PC   G+C + P
Sbjct: 723 DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSP 779

Query: 240 GGDTYSAP 263
            G + + P
Sbjct: 780 KGASCNCP 787



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           C    D CS    CLNGG+C       Y C C    ++G  CE     C     L G G 
Sbjct: 718 CCLHSDYCS-QNTCLNGGKCSWTHGAGYVCKCPPQ-FSGKHCEQGRENCTFAPCLEG-GT 774

Query: 467 CYDTYGGFVCAC 502
           C  +  G  C C
Sbjct: 775 CILSPKGASCNC 786


>AB011535-1|BAA32463.1|  573|Homo sapiens MEGF1 protein.
          Length = 573

 Score = 59.3 bits (137), Expect = 1e-08
 Identities = 25/66 (37%), Positives = 36/66 (54%)
 Frame = +2

Query: 254 LCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNVNEC 433
           +C CPP ++G++CE   + C+  A CL GG C+ +    +C+C    YTG RCE     C
Sbjct: 195 VCKCPPQFSGKHCEQGRENCT-FAPCLEGGTCILSPKGASCNCPHP-YTGDRCEMEARGC 252

Query: 434 EEDRAL 451
            E   L
Sbjct: 253 SEGHCL 258



 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELE 173
           Y C C  +++G +CE    + C  A C  G  C+   +G  SC+CP  Y G  CE+E
Sbjct: 194 YVCKCPPQFSGKHCE-QGRENCTFAPCLEGGTCILSPKGA-SCNCPHPYTGDRCEME 248



 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/68 (30%), Positives = 30/68 (44%)
 Frame = +3

Query: 60  DPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPP 239
           D C+   C +G +C       Y C CPP + G +CE        C   PC   G+C + P
Sbjct: 173 DYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSP 229

Query: 240 GGDTYSAP 263
            G + + P
Sbjct: 230 KGASCNCP 237



 Score = 34.3 bits (75), Expect = 0.37
 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVN-NYTCDCTATGYTGARCETNVNECEEDRALCGHGV 466
           C    D CS    CLNGG+C       Y C C    ++G  CE     C     L G G 
Sbjct: 168 CCLHSDYCS-QNTCLNGGKCSWTHGAGYVCKCPPQ-FSGKHCEQGRENCTFAPCLEG-GT 224

Query: 467 CYDTYGGFVCAC 502
           C  +  G  C C
Sbjct: 225 CILSPKGASCNC 236


>AK074499-1|BAC11024.1|  636|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90018 fis, clone HEMBA1000732, highly similar to
           Homo sapiens mRNA for latent transforming growth
           factor-beta ).
          Length = 636

 Score = 58.8 bits (136), Expect = 1e-08
 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
 Frame = +2

Query: 257 CTCPPGY-TGRNCET--DVDECS--GAAACLNGGRCVDAVNNYTC--DCTATGYTGAR-- 409
           C CPPG+  G +  +  DVDEC   G A C    RC ++  +Y C  DC    + G    
Sbjct: 42  CICPPGHRAGPDLASCLDVDECRERGPALC-RSQRCENSPGSYRCVRDCDPGYHAGPEGT 100

Query: 410 CETNVNECEEDRALCGHGVCYDTYGGFVCACQPATP 517
           C+ +VNECE  + +CG  +C +  G F+C C P +P
Sbjct: 101 CD-DVNECETLQGVCGAALCENVEGSFLCVC-PNSP 134



 Score = 50.0 bits (114), Expect = 7e-06
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
 Frame = +2

Query: 293 ETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNVNECEEDRA---L 451
           E + +EC     C NG RCV     +TC C   GY    T   C  ++NEC+E  A   L
Sbjct: 543 ELEAEECGILDGCTNG-RCVRVPEGFTCRCF-DGYRLDMTRMAC-VDINECDEAEAASPL 599

Query: 452 CGHGVCYDTYGGFVCACQP 508
           C +  C +T G F C C+P
Sbjct: 600 CVNARCLNTDGSFRCICRP 618



 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
 Frame = +2

Query: 257 CTCPPGY---TGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDC---TATGYTGARCET 418
           C C  GY   T R    D DEC+       GGRCV+ V +Y C C        +  RC +
Sbjct: 291 CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 350

Query: 419 NVNECEEDRALCGHGVCYDTYGG-FVCACQPATPGSTATGC 538
           N ++  +D      GVC+   G   VC+       +T T C
Sbjct: 351 NESQSLDDNL----GVCWQEVGADLVCSHPRLDRQATYTEC 387



 Score = 40.3 bits (90), Expect = 0.006
 Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
 Frame = +2

Query: 290 CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTG---ARCETNVNEC-EEDRALCG 457
           C  DVDECS    C   G C +   ++ C C      G   A C  +V+EC E   ALC 
Sbjct: 15  CPADVDECSEEDLC-QSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCR 72

Query: 458 HGVCYDTYGGFVCA--CQPATPGSTATGCRRVRQ 553
              C ++ G + C   C P         C  V +
Sbjct: 73  SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNE 106



 Score = 38.3 bits (85), Expect = 0.023
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
 Frame = +2

Query: 386 ATGYTGAR--CETNVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           A G  G R  C  +V+EC E+  LC  G+C +T G F C C P
Sbjct: 5   AGGGPGLRTPCPADVDECSEED-LCQSGICTNTDGSFECICPP 46



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
 Frame = +3

Query: 3   YECHCTARYTGN----NC-EVDAGDPCASAACRHGARCVEDGRGDYSC--DCPPGYH--- 152
           +EC C   +       +C +VD       A CR   RC E+  G Y C  DC PGYH   
Sbjct: 40  FECICPPGHRAGPDLASCLDVDECRERGPALCR-SQRC-ENSPGSYRCVRDCDPGYHAGP 97

Query: 153 -GTYCELE--VSLDPLCVAGPCRN 215
            GT  ++    +L  +C A  C N
Sbjct: 98  EGTCDDVNECETLQGVCGAALCEN 121


>Y00692-1|CAA68687.1|  676|Homo sapiens preproprotein S protein.
          Length = 676

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 143 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 200

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 201 DVDECSLKPSICGTAVCKNIPGDFECEC 228



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 176

Query: 231 VPPG 242
             PG
Sbjct: 177 NTPG 180



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 141 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 231



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 182 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232


>M57853-1|AAA60357.1|  676|Homo sapiens S protein protein.
          Length = 676

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 143 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 200

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 201 DVDECSLKPSICGTAVCKNIPGDFECEC 228



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 176

Query: 231 VPPG 242
             PG
Sbjct: 177 NTPG 180



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 141 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 231



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 182 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232


>M36564-1|AAA60180.1|  650|Homo sapiens PROS1 protein.
          Length = 650

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 117 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 174

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 175 DVDECSLKPSICGTAVCKNIPGDFECEC 202



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 93  DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 150

Query: 231 VPPG 242
             PG
Sbjct: 151 NTPG 154



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 115 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 173

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 174 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 205



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 156 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 206


>M15036-1|AAA36479.1|  676|Homo sapiens protein ( Human vitamin
           K-dependent plasma protein S mRNA, complete cds. ).
          Length = 676

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 143 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 200

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 201 DVDECSLKPSICGTAVCKNIPGDFECEC 228



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 176

Query: 231 VPPG 242
             PG
Sbjct: 177 NTPG 180



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 141 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 231



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 182 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232


>BC126986-1|AAI26987.1|  393|Homo sapiens FLJ37440 protein protein.
          Length = 393

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 35/76 (46%), Positives = 42/76 (55%), Gaps = 9/76 (11%)
 Frame = +2

Query: 302 VDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARC----ETNVNECE----EDR-ALC 454
           + ECS +  C NGG CV+ VN Y C C   G TG RC    +T+VNECE    E R  LC
Sbjct: 137 ISECS-SQPCQNGGTCVEGVNQYRCIC-PPGRTGNRCQHQAQTDVNECELYGQEGRPRLC 194

Query: 455 GHGVCYDTYGGFVCAC 502
            H  C +T G + C C
Sbjct: 195 MH-ACVNTPGSYRCTC 209



 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
 Frame = +2

Query: 257 CTCPPGYTGRNC----ETDVDEC------SGAAACLNGGRCVDAVNNYTCDCTATGY--- 397
           C CPPG TG  C    +TDV+EC           C++   CV+   +Y C C   GY   
Sbjct: 160 CICPPGRTGNRCQHQAQTDVNECELYGQEGRPRLCMHA--CVNTPGSYRCTCPG-GYRTL 216

Query: 398 -TGARCETNVNECEEDRALCGHG-VCYDTYGGFVCACQPATPGS 523
             G  CE +V+EC   + +C  G  C +T G F C       GS
Sbjct: 217 ADGKSCE-DVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGS 259



 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 20/59 (33%), Positives = 26/59 (44%)
 Frame = +3

Query: 9   CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
           C     +TG          C+S  C++G  CVE G   Y C CPPG  G  C+ +   D
Sbjct: 121 CLPNGTWTGEQPHCRGISECSSQPCQNGGTCVE-GVNQYRCICPPGRTGNRCQHQAQTD 178



 Score = 34.7 bits (76), Expect = 0.28
 Identities = 31/91 (34%), Positives = 33/91 (36%), Gaps = 18/91 (19%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDA----------GDPCASAACRHGARCVEDGRGDYSCDCPPGYH 152
           Y C C    TGN C+  A          G       C H   CV    G Y C CP GY 
Sbjct: 158 YRCICPPGRTGNRCQHQAQTDVNECELYGQEGRPRLCMHA--CVNTP-GSYRCTCPGGYR 214

Query: 153 ----GTYCELE---VSLDPLCVAG-PCRNNG 221
               G  CE     V L P+C  G  C N G
Sbjct: 215 TLADGKSCEDVDECVGLQPVCPQGTTCINTG 245


>BC015801-1|AAH15801.1|  676|Homo sapiens PROS1 protein protein.
          Length = 676

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 143 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 200

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 201 DVDECSLKPSICGTAVCKNIPGDFECEC 228



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 176

Query: 231 VPPG 242
             PG
Sbjct: 177 NTPG 180



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 141 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 231



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 182 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232


>AY308744-1|AAP45054.1|  497|Homo sapiens protein S (alpha) protein.
          Length = 497

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
 Frame = +2

Query: 257 CTCPPGYTGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDCTATGY---TGARCET 418
           CTC PG+ G  CE D++EC   +  +NGG    C +   +Y C C   G+   +  +   
Sbjct: 143 CTCKPGWQGEKCEFDINECKDPSN-INGGCSQICDNTPGSYHCSC-KNGFVMLSNKKDCK 200

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCAC 502
           +V+EC    ++CG  VC +  G F C C
Sbjct: 201 DVDECSLKPSICGTAVCKNIPGDFECEC 228



 Score = 41.5 bits (93), Expect = 0.002
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
 Frame = +3

Query: 60  DPCASAACRH-GARCVEDGRGDYSCDCPPGYHGTYCELEVS--LDPLCVAGPCRNNGSCS 230
           D C+   C   G    +DG+  ++C C PG+ G  CE +++   DP  + G C  +  C 
Sbjct: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGC--SQICD 176

Query: 231 VPPG 242
             PG
Sbjct: 177 NTPG 180



 Score = 30.3 bits (65), Expect = 6.0
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
 Frame = +3

Query: 3   YECHCTARYTGNNCEVDAGDPCASAACRHG--ARCVEDGRGDYSCDCPPGY----HGTYC 164
           + C C   + G  CE D  + C   +  +G  ++  ++  G Y C C  G+    +   C
Sbjct: 141 FTCTCKPGWQGEKCEFDINE-CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199

Query: 165 E--LEVSLDP-LCVAGPCRN---NGSCSVPPG 242
           +   E SL P +C    C+N   +  C  P G
Sbjct: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEG 231



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
 Frame = +3

Query: 3   YECHCTARYT--GNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGY 149
           Y C C   +    N  +    D C+      G    ++  GD+ C+CP GY
Sbjct: 182 YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232


>AK074396-1|BAB85069.1|  220|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23816 fis, clone HSI02685. ).
          Length = 220

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 7/89 (7%)
 Frame = +2

Query: 263 CPPGYTGRN--CETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGY----TGARCETNV 424
           CPPG+  +N  C TD+DEC     C +   C +   +Y C C A GY    +G  C+ ++
Sbjct: 11  CPPGFIRQNGVC-TDLDECRVRNLCQHA--CRNTEGSYQCLCPA-GYRLLPSGKNCQ-DI 65

Query: 425 NECEEDRALCGHG-VCYDTYGGFVCACQP 508
           NECEE+   CG G +C++T G + C   P
Sbjct: 66  NECEEESIECGPGQMCFNTRGSYQCVDTP 94


>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
            (AA -19 to 4525) protein.
          Length = 4544

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 31/79 (39%), Positives = 40/79 (50%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C  RYTG+ CE+D    C    CR+G  C     G  +C CP G+ G  C  +V   
Sbjct: 4219 KCRCQPRYTGDKCELDQ---CWEH-CRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV--- 4271

Query: 186  PLCVAGPCRNNGSCSVPPG 242
              C AG C NN +C+V  G
Sbjct: 4272 --C-AGYCANNSTCTVNQG 4287



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +2

Query: 242  RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCET 418
            RR   C C P YTG  CE  +D+C     C NGG C  + +   TC C  TG+TG +C  
Sbjct: 4215 RRQPKCRCQPRYTGDKCE--LDQC--WEHCRNGGTCAASPSGMPTCRC-PTGFTGPKCTQ 4269

Query: 419  NV 424
             V
Sbjct: 4270 QV 4271



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
            C C PG+ G  C+    +CSG   C N G C + A  +  C CTA  + G+RCE  VN+C
Sbjct: 4292 CRCLPGFLGDRCQ--YRQCSG--YCENFGTCQMAADGSRQCRCTAY-FEGSRCE--VNKC 4344

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
               R L G  V     G   C C   T G  A  C
Sbjct: 4345 --SRCLEGACVVNKQSGDVTCNC---TDGRVAPSC 4374



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 25/76 (32%), Positives = 33/76 (43%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C CTA + G+ CEV+    C   AC      V    GD +C+C  G     C       
Sbjct: 4327 QCRCTAYFEGSRCEVNKCSRCLEGAC-----VVNKQSGDVTCNCTDGRVAPSC------- 4374

Query: 186  PLCVAGPCRNNGSCSV 233
             L   G C N GSC++
Sbjct: 4375 -LTCVGHCSNGGSCTM 4389



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  C  + R    C C P Y G  CEL+   +       CRN G+C+  P G
Sbjct: 4204 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWE------HCRNGGTCAASPSG 4252



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/79 (27%), Positives = 31/79 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C       CA   C + + C  +      C C PG+ G  C+       
Sbjct: 4256 CRCPTGFTGPKCTQQV---CAGY-CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR----- 4306

Query: 189  LCVAGPCRNNGSCSVPPGG 245
             C +G C N G+C +   G
Sbjct: 4307 QC-SGYCENFGTCQMAADG 4324



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/68 (25%), Positives = 26/68 (38%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C   + G+ C+        S  C +   C     G   C C   + G+ C  EV+  
Sbjct: 4291 QCRCLPGFLGDRCQYRQ----CSGYCENFGTCQMAADGSRQCRCTAYFEGSRC--EVNKC 4344

Query: 186  PLCVAGPC 209
              C+ G C
Sbjct: 4345 SRCLEGAC 4352



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 1/61 (1%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            DP     C+  ARC+      D   DC        CE      P   + PC NN S  +P
Sbjct: 1105 DPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPP---SHPCANNTSVCLP 1161

Query: 237  P 239
            P
Sbjct: 1162 P 1162



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 17/56 (30%), Positives = 22/56 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G    +C T V  CS   +C    + +       C C     TG RCE +V
Sbjct: 4363 CNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMP-----ECQC-PPHMTGPRCEEHV 4412



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 16/56 (28%), Positives = 21/56 (37%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            C+CT      +C    G       C +G  C  + +    C CPP   G  CE  V
Sbjct: 4363 CNCTDGRVAPSCLTCVGH------CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHV 4412


>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
            lipoprotein-related protein 1 (alpha-2-macroglobulin
            receptor) protein.
          Length = 4544

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 31/79 (39%), Positives = 40/79 (50%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C  RYTG+ CE+D    C    CR+G  C     G  +C CP G+ G  C  +V   
Sbjct: 4219 KCRCQPRYTGDKCELDQ---CWEH-CRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV--- 4271

Query: 186  PLCVAGPCRNNGSCSVPPG 242
              C AG C NN +C+V  G
Sbjct: 4272 --C-AGYCANNSTCTVNQG 4287



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +2

Query: 242  RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCET 418
            RR   C C P YTG  CE  +D+C     C NGG C  + +   TC C  TG+TG +C  
Sbjct: 4215 RRQPKCRCQPRYTGDKCE--LDQC--WEHCRNGGTCAASPSGMPTCRC-PTGFTGPKCTQ 4269

Query: 419  NV 424
             V
Sbjct: 4270 QV 4271



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
            C C PG+ G  C+    +CSG   C N G C + A  +  C CTA  + G+RCE  VN+C
Sbjct: 4292 CRCLPGFLGDRCQ--YRQCSG--YCENFGTCQMAADGSRQCRCTAY-FEGSRCE--VNKC 4344

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
               R L G  V     G   C C   T G  A  C
Sbjct: 4345 --SRCLEGACVVNKQSGDVTCNC---TDGRVAPSC 4374



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 25/76 (32%), Positives = 33/76 (43%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C CTA + G+ CEV+    C   AC      V    GD +C+C  G     C       
Sbjct: 4327 QCRCTAYFEGSRCEVNKCSRCLEGAC-----VVNKQSGDVTCNCTDGRVAPSC------- 4374

Query: 186  PLCVAGPCRNNGSCSV 233
             L   G C N GSC++
Sbjct: 4375 -LTCVGHCSNGGSCTM 4389



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  C  + R    C C P Y G  CEL+   +       CRN G+C+  P G
Sbjct: 4204 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWE------HCRNGGTCAASPSG 4252



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/79 (27%), Positives = 31/79 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C       CA   C + + C  +      C C PG+ G  C+       
Sbjct: 4256 CRCPTGFTGPKCTQQV---CAGY-CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR----- 4306

Query: 189  LCVAGPCRNNGSCSVPPGG 245
             C +G C N G+C +   G
Sbjct: 4307 QC-SGYCENFGTCQMAADG 4324



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/68 (25%), Positives = 26/68 (38%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C   + G+ C+        S  C +   C     G   C C   + G+ C  EV+  
Sbjct: 4291 QCRCLPGFLGDRCQYRQ----CSGYCENFGTCQMAADGSRQCRCTAYFEGSRC--EVNKC 4344

Query: 186  PLCVAGPC 209
              C+ G C
Sbjct: 4345 SRCLEGAC 4352



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 1/61 (1%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            DP     C+  ARC+      D   DC        CE      P   + PC NN S  +P
Sbjct: 1105 DPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPP---SHPCANNTSVCLP 1161

Query: 237  P 239
            P
Sbjct: 1162 P 1162



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 17/56 (30%), Positives = 22/56 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G    +C T V  CS   +C    + +       C C     TG RCE +V
Sbjct: 4363 CNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMP-----ECQC-PPHMTGPRCEEHV 4412



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 16/56 (28%), Positives = 21/56 (37%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            C+CT      +C    G       C +G  C  + +    C CPP   G  CE  V
Sbjct: 4363 CNCTDGRVAPSCLTCVGH------CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHV 4412


>BC111690-1|AAI11691.1|  807|Homo sapiens SCUBE2 protein protein.
          Length = 807

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDC---TATGYTGARC 412
           C+C PGY   GR CE D+DEC      LNGG    C++   NY C C       + G  C
Sbjct: 71  CSCKPGYQGEGRQCE-DIDECGNE---LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
             +V+EC E+   C H  C +  G + C C+
Sbjct: 127 -LDVDECLENNGGCQH-TCVNVMGSYECCCK 155



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
           C C  G+      ++C+ DVDECS    C +   C++    + C C   GYT  G     
Sbjct: 347 CGCKKGFKLLTDEKSCQ-DVDECSLDRTCDHS--CINHPGTFACACNR-GYTLYGFTHCG 402

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC  +   C   VC +T G + C C P
Sbjct: 403 DTNECSINNGGCQQ-VCVNTVGSYECQCHP 431



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 5/100 (5%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           CTC  G+     G NC  DVDEC      C +   CV+ + +Y C C    +      T 
Sbjct: 111 CTCFDGFMLAHDGHNC-LDVDECLENNGGCQH--TCVNVMGSYECCCKEGFFLSDNQHTC 167

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCR 541
           ++  EE  +      C +   G    C+ A  GS A  CR
Sbjct: 168 IHRSEEGLS------CMNKDHGCSHICKEAPRGSVACECR 201


>AK131552-1|BAD18686.1|  682|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16792 fis, clone TBAES2007379, moderately
           similar to Homo sapiens signal peptide, CUB domain,
           EGF-like 2 (SCUBE2). ).
          Length = 682

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDC---TATGYTGARC 412
           C+C PGY   GR CE D+DEC      LNGG    C++   NY C C       + G  C
Sbjct: 71  CSCKPGYQGEGRQCE-DIDECGNE---LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
             +V+EC E+   C H  C +  G + C C+
Sbjct: 127 -LDVDECLENNGGCQH-TCVNVMGSYECCCK 155



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
           C C  G+      ++C+ DVDECS    C +   C++    + C C   GYT  G     
Sbjct: 347 CGCKKGFKLLTDEKSCQ-DVDECSLDRTCDHS--CINHPGTFACACNR-GYTLYGFTHCG 402

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC  +   C   VC +T G + C C P
Sbjct: 403 DTNECSINNGGCQQ-VCVNTVGSYECQCHP 431



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 5/100 (5%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           CTC  G+     G NC  DVDEC      C +   CV+ + +Y C C    +      T 
Sbjct: 111 CTCFDGFMLAHDGHNC-LDVDECLENNGGCQH--TCVNVMGSYECCCKEGFFLSDNQHTC 167

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCR 541
           ++  EE  +      C +   G    C+ A  GS A  CR
Sbjct: 168 IHRSEEGLS------CMNKDHGCSHICKEAPRGSVACECR 201


>AK123039-1|BAC85521.1|  971|Homo sapiens protein ( Homo sapiens
           cDNA FLJ41044 fis, clone NT2RP7000466, highly  similar
           to Mus musculus CUB domain and EGF-like repeat
           containing 1 (Cegf1). ).
          Length = 971

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDC---TATGYTGARC 412
           C+C PGY   GR CE D+DEC      LNGG    C++   NY C C       + G  C
Sbjct: 71  CSCKPGYQGEGRQCE-DIDECGNE---LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
             +V+EC E+   C H  C +  G + C C+
Sbjct: 127 -LDVDECLENNGGCQH-TCVNVMGSYECCCK 155



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
           C C  G+      ++C+ DVDECS    C +   C++    + C C   GYT  G     
Sbjct: 347 CGCKKGFKLLTDEKSCQ-DVDECSLDRTCDHS--CINHPGTFACACNR-GYTLYGFTHCG 402

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC  +   C   VC +T G + C C P
Sbjct: 403 DTNECSINNGGCQQ-VCVNTVGSYECQCHP 431



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 5/100 (5%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           CTC  G+     G NC  DVDEC      C +   CV+ + +Y C C    +      T 
Sbjct: 111 CTCFDGFMLAHDGHNC-LDVDECLENNGGCQH--TCVNVMGSYECCCKEGFFLSDNQHTC 167

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCR 541
           ++  EE  +      C +   G    C+ A  GS A  CR
Sbjct: 168 IHRSEEGLS------CMNKDHGCSHICKEAPRGSVACECR 201


>AJ400877-1|CAB92285.1|  999|Homo sapiens CEGP1 protein protein.
          Length = 999

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
 Frame = +2

Query: 257 CTCPPGY--TGRNCETDVDECSGAAACLNGG---RCVDAVNNYTCDC---TATGYTGARC 412
           C+C PGY   GR CE D+DEC      LNGG    C++   NY C C       + G  C
Sbjct: 71  CSCKPGYQGEGRQCE-DIDECGNE---LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126

Query: 413 ETNVNECEEDRALCGHGVCYDTYGGFVCACQ 505
             +V+EC E+   C H  C +  G + C C+
Sbjct: 127 -LDVDECLENNGGCQH-TCVNVMGSYECCCK 155



 Score = 44.4 bits (100), Expect = 3e-04
 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYT--GARCET 418
           C C  G+      ++C+ DVDECS    C +   C++    + C C   GYT  G     
Sbjct: 347 CGCKKGFKLLTDEKSCQ-DVDECSLDRTCDHS--CINHPGTFACACNR-GYTLYGFTHCG 402

Query: 419 NVNECEEDRALCGHGVCYDTYGGFVCACQP 508
           + NEC  +   C   VC +T G + C C P
Sbjct: 403 DTNECSINNGGCQQ-VCVNTVGSYECQCHP 431



 Score = 37.9 bits (84), Expect = 0.030
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 5/100 (5%)
 Frame = +2

Query: 257 CTCPPGYT----GRNCETDVDEC-SGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETN 421
           CTC  G+     G NC  DVDEC      C +   CV+ + +Y C C    +      T 
Sbjct: 111 CTCFDGFMLAHDGHNC-LDVDECLENNGGCQH--TCVNVMGSYECCCKEGFFLSDNQHTC 167

Query: 422 VNECEEDRALCGHGVCYDTYGGFVCACQPATPGSTATGCR 541
           ++  EE  +      C +   G    C+ A  GS A  CR
Sbjct: 168 IHRSEEGLS------CMNKDHGCSHICKEAPRGSVACECR 201


>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
            protein protein.
          Length = 4544

 Score = 57.6 bits (133), Expect = 3e-08
 Identities = 31/79 (39%), Positives = 40/79 (50%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C  RYTG+ CE+D    C    CR+G  C     G  +C CP G+ G  C  +V   
Sbjct: 4219 KCRCQPRYTGDKCELDQ---CWEH-CRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV--- 4271

Query: 186  PLCVAGPCRNNGSCSVPPG 242
              C AG C NN +C+V  G
Sbjct: 4272 --C-AGYCANNSTCTVNQG 4287



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
 Frame = +2

Query: 242  RRHLLCTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNY-TCDCTATGYTGARCET 418
            RR   C C P YTG  CE  +D+C     C NGG C  + +   TC C  TG+TG +C  
Sbjct: 4215 RRQPKCRCQPRYTGDKCE--LDQC--WEHCRNGGTCAASPSGMPTCRC-PTGFTGPKCTQ 4269

Query: 419  NV 424
             V
Sbjct: 4270 QV 4271



 Score = 47.2 bits (107), Expect = 5e-05
 Identities = 36/95 (37%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRC-VDAVNNYTCDCTATGYTGARCETNVNEC 433
            C C PG+ G  C+    +CSG   C N G C + A  +  C CTA  + G+RCE  VN+C
Sbjct: 4292 CRCLPGFLGDRCQ--YRQCSG--YCENFGTCQMAADGSRQCRCTAY-FEGSRCE--VNKC 4344

Query: 434  EEDRALCGHGVCYDTYGGFVCACQPATPGSTATGC 538
               R L G  V     G   C C   T G  A  C
Sbjct: 4345 --SRCLEGACVVNKQSGDVTCNC---TDGRVAPSC 4374



 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 25/76 (32%), Positives = 33/76 (43%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C CTA + G+ CEV+    C   AC      V    GD +C+C  G     C       
Sbjct: 4327 QCRCTAYFEGSRCEVNKCSRCLEGAC-----VVNKQSGDVTCNCTDGRVAPSC------- 4374

Query: 186  PLCVAGPCRNNGSCSV 233
             L   G C N GSC++
Sbjct: 4375 -LTCVGHCSNGGSCTM 4389



 Score = 39.9 bits (89), Expect = 0.007
 Identities = 19/55 (34%), Positives = 25/55 (45%)
 Frame = +3

Query: 81   CRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVPPGG 245
            C +G  C  + R    C C P Y G  CEL+   +       CRN G+C+  P G
Sbjct: 4204 CFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWE------HCRNGGTCAASPSG 4252



 Score = 36.3 bits (80), Expect = 0.091
 Identities = 22/79 (27%), Positives = 31/79 (39%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLDP 188
            C C   +TG  C       CA   C + + C  +      C C PG+ G  C+       
Sbjct: 4256 CRCPTGFTGPKCTQQV---CAGY-CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR----- 4306

Query: 189  LCVAGPCRNNGSCSVPPGG 245
             C +G C N G+C +   G
Sbjct: 4307 QC-SGYCENFGTCQMAADG 4324



 Score = 31.5 bits (68), Expect = 2.6
 Identities = 17/68 (25%), Positives = 26/68 (38%)
 Frame = +3

Query: 6    ECHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEVSLD 185
            +C C   + G+ C+        S  C +   C     G   C C   + G+ C  EV+  
Sbjct: 4291 QCRCLPGFLGDRCQYRQ----CSGYCENFGTCQMAADGSRQCRCTAYFEGSRC--EVNKC 4344

Query: 186  PLCVAGPC 209
              C+ G C
Sbjct: 4345 SRCLEGAC 4352



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 1/61 (1%)
 Frame = +3

Query: 60   DPCASAACRHGARCVEDGRG-DYSCDCPPGYHGTYCELEVSLDPLCVAGPCRNNGSCSVP 236
            DP     C+  ARC+      D   DC        CE      P   + PC NN S  +P
Sbjct: 1105 DPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPP---SHPCANNTSVCLP 1161

Query: 237  P 239
            P
Sbjct: 1162 P 1162



 Score = 30.7 bits (66), Expect = 4.5
 Identities = 17/56 (30%), Positives = 22/56 (39%)
 Frame = +2

Query: 257  CTCPPGYTGRNCETDVDECSGAAACLNGGRCVDAVNNYTCDCTATGYTGARCETNV 424
            C C  G    +C T V  CS   +C    + +       C C     TG RCE +V
Sbjct: 4363 CNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMP-----ECQC-PPHMTGPRCEEHV 4412



 Score = 29.9 bits (64), Expect = 7.9
 Identities = 16/56 (28%), Positives = 21/56 (37%)
 Frame = +3

Query: 9    CHCTARYTGNNCEVDAGDPCASAACRHGARCVEDGRGDYSCDCPPGYHGTYCELEV 176
            C+CT      +C    G       C +G  C  + +    C CPP   G  CE  V
Sbjct: 4363 CNCTDGRVAPSCLTCVGH------CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHV 4412


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,957,132
Number of Sequences: 237096
Number of extensions: 1955282
Number of successful extensions: 29515
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8319
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21523
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6972732040
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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