SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbVm1307
         (672 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste...   154   2e-36
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:...   129   5e-29
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car...   127   2e-28
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb...   117   3e-25
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO...    76   7e-13
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas...    62   9e-09
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar...    60   5e-08
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar...    59   1e-07
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar...    57   4e-07
UniRef50_A6QAA3 Cluster: Phosphoribosylaminoimidazole-succinocar...    56   6e-07
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar...    55   1e-06
UniRef50_Q8TX83 Cluster: Phosphoribosylaminoimidazole-succinocar...    54   2e-06
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar...    54   3e-06
UniRef50_Q7M9X5 Cluster: Phosphoribosylaminoimidazole-succinocar...    54   4e-06
UniRef50_Q49WJ0 Cluster: Phosphoribosylaminoimidazole-succinocar...    53   7e-06
UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylas...    53   7e-06
UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylas...    49   9e-05
UniRef50_P73471 Cluster: Phosphoribosylaminoimidazole-succinocar...    48   2e-04
UniRef50_Q6LZT3 Cluster: Phosphoribosylaminoimidazole-succinocar...    48   3e-04
UniRef50_Q9X0X0 Cluster: Phosphoribosylaminoimidazole-succinocar...    48   3e-04
UniRef50_A4SAQ9 Cluster: Phosphoribosylaminoimidazole-succinocar...    46   0.001
UniRef50_Q8G5A9 Cluster: Phosphoribosylaminoimidazole-succinocar...    46   0.001
UniRef50_Q4J8G0 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.001
UniRef50_Q87Y59 Cluster: Phosphoribosylaminoimidazole-succinocar...    45   0.001
UniRef50_UPI00015BB105 Cluster: phosphoribosylaminoimidazole-suc...    45   0.002
UniRef50_A3H6Y2 Cluster: Phosphoribosylaminoimidazole-succinocar...    44   0.003
UniRef50_Q9RXT0 Cluster: Phosphoribosylaminoimidazole-succinocar...    44   0.003
UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2; Anaplasmataceae...    44   0.004
UniRef50_Q73PW0 Cluster: Phosphoribosylaminoimidazole-succinocar...    43   0.008
UniRef50_Q8ES99 Cluster: Phosphoribosylaminoimidazole-succinocar...    42   0.014
UniRef50_Q8TIS9 Cluster: Phosphoribosylaminoimidazole-succinocar...    42   0.014
UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE - Methanos...    41   0.024
UniRef50_Q3WE59 Cluster: SAICAR synthetase; n=5; Bacteria|Rep: S...    41   0.031
UniRef50_P0A7E0 Cluster: Phosphoribosylaminoimidazole-succinocar...    41   0.031
UniRef50_A7CZ13 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    40   0.041
UniRef50_Q7V5X1 Cluster: Phosphoribosylaminoimidazole-succinocar...    40   0.041
UniRef50_Q88U22 Cluster: Phosphoribosylaminoimidazole-succinocar...    40   0.041
UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole (NC...    40   0.055
UniRef50_A0RW02 Cluster: Phosphoribosylaminoimidazole-succinocar...    40   0.055
UniRef50_Q8ZCD2 Cluster: Phosphoribosylaminoimidazole-succinocar...    40   0.072
UniRef50_Q03Y92 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    39   0.096
UniRef50_Q7UJ19 Cluster: Phosphoribosylaminoimidazole-succinocar...    39   0.13 
UniRef50_Q7VAN8 Cluster: Phosphoribosylaminoimidazole-succinocar...    38   0.17 
UniRef50_Q648Z8 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    38   0.29 
UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylas...    37   0.39 
UniRef50_Q1IPE1 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.51 
UniRef50_Q8ZZK5 Cluster: Phosphoribosylaminoimidazole-succinocar...    37   0.51 
UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole c...    37   0.51 
UniRef50_Q1MRH1 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    36   0.67 
UniRef50_P43060 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   0.67 
UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylas...    36   1.2  
UniRef50_Q5JD27 Cluster: Phosphoribosylaminoimidazolesuccinocarb...    36   1.2  
UniRef50_P38025 Cluster: Phosphoribosylaminoimidazole-succinocar...    36   1.2  
UniRef50_Q98I23 Cluster: Putative phosphoribosylaminoimidazole-s...    36   1.2  
UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylas...    35   2.1  
UniRef50_Q9C1J4 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   2.1  
UniRef50_A0Q508 Cluster: Phosphoribosylaminoimidazole-succinocar...    34   2.7  
UniRef50_Q4UML8 Cluster: Phosphoribosylaminoimidazole-succinocar...    34   2.7  
UniRef50_Q8F0I0 Cluster: Phosphoribosylaminoimidazole-succinocar...    34   2.7  
UniRef50_Q3Z881 Cluster: Phosphoribosylaminoimidazole-succinocar...    33   4.8  
UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: Pq...    33   4.8  
UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n...    33   4.8  
UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLAS...    33   6.3  
UniRef50_Q2UIJ7 Cluster: Predicted protein; n=1; Aspergillus ory...    33   6.3  
UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylas...    33   6.3  
UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium ja...    33   8.3  

>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
           melanogaster|Rep: CG17024-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 395

 Score =  154 bits (373), Expect = 2e-36
 Identities = 72/135 (53%), Positives = 96/135 (71%), Gaps = 1/135 (0%)
 Frame = -1

Query: 657 FLKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQ-IQL*RSSNGRDEVDYMR 481
           F+K NP VPEG+RF PPKQET  +       P+       S   +      G DEV  MR
Sbjct: 110 FIKLNPEVPEGYRFAPPKQETCFKD-DSSHDPLWCDEQILSSNFECNGLIIGADEVQIMR 168

Query: 480 KATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVD 301
           + ++++FE+LE+AW  ++CAL+DMK+EFGVD +G+I+LAD+IDSD+WR+WP+GDKRLMVD
Sbjct: 169 RTSLVVFEVLERAWKTKNCALVDMKVEFGVDEDGNILLADIIDSDTWRIWPAGDKRLMVD 228

Query: 300 KQVYRNLTTVTAADL 256
           K VY NL TVT +DL
Sbjct: 229 KTVYINLDTVTDSDL 243



 Score = 32.7 bits (71), Expect = 8.3
 Identities = 13/27 (48%), Positives = 19/27 (70%)
 Frame = -3

Query: 256 STVKRNFAWVKDQLDFLKPTIHHKVVV 176
           +TVKRN++WV +QL  + P   H VV+
Sbjct: 244 NTVKRNYSWVIEQLSSIAPPQDHLVVI 270


>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
           Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)] - Homo sapiens (Human)
          Length = 425

 Score =  129 bits (312), Expect = 5e-29
 Identities = 70/135 (51%), Positives = 83/135 (61%), Gaps = 1/135 (0%)
 Frame = -1

Query: 657 FLKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRK 478
           FLKRNPGV EG++F PPK E F +                ++        G+ EVD M  
Sbjct: 108 FLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSH 167

Query: 477 ATILIFEILEKAWALRDCALIDMKIEFGVD-TEGSIVLADVIDSDSWRLWPSGDKRLMVD 301
           AT  IFEILEK+W  ++C L+DMKIEFGVD T   IVLADVID+DSWRLWPSGD+    D
Sbjct: 168 ATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKD 227

Query: 300 KQVYRNLTTVTAADL 256
           KQ YR+L  VT   L
Sbjct: 228 KQSYRDLKEVTPEGL 242



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 41/84 (48%), Positives = 54/84 (64%), Gaps = 1/84 (1%)
 Frame = -3

Query: 250 VKRNFAWVKDQLDFL-KPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHK 74
           VK+NF WV ++++ L K     +VVV MGS +D  HC+KI KA    G+  +LRVTSAHK
Sbjct: 245 VKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHK 304

Query: 73  ATEETLRIMQQYEDTHGALVFIAV 2
             +ETLRI  +YE      VF+AV
Sbjct: 305 GPDETLRIKAEYEGDGIPTVFVAV 328



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 22/28 (78%), Positives = 26/28 (92%)
 Frame = -2

Query: 593 FFKDDANHDPQWSEEQIISAKFNYNGLL 510
           FFKDDAN+DPQWSEEQ+I+AKF + GLL
Sbjct: 129 FFKDDANNDPQWSEEQLIAAKFCFAGLL 156


>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
           carboxylase, phosphoribosylaminoimidazole
           succinocarboxamide synthetase; n=2; Coelomata|Rep:
           phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase - Bos Taurus
          Length = 402

 Score =  127 bits (307), Expect = 2e-28
 Identities = 73/140 (52%), Positives = 89/140 (63%), Gaps = 6/140 (4%)
 Frame = -1

Query: 657 FLKRNPGVPEGFRFTPPKQETFLQ--G*RKPR--SPMVRGANH-FSQIQL*RSSNGRDEV 493
           FLKRNPGV EG++F PPK E F +      P+     +  AN  F+ + +     G+ EV
Sbjct: 111 FLKRNPGVKEGYKFYPPKVEMFFKDDANNDPQWSEEQLIAANFCFAGLVI-----GQTEV 165

Query: 492 DYMRKATILIFEILEKAWALRDCALIDMKIEFGVDT-EGSIVLADVIDSDSWRLWPSGDK 316
           D M  AT  IFEILEK+W  ++C L+DMKIEFGVD     IVLADVID+DSWRLWPSGD+
Sbjct: 166 DIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVITREIVLADVIDNDSWRLWPSGDR 225

Query: 315 RLMVDKQVYRNLTTVTAADL 256
               DKQ YR+L  VT   L
Sbjct: 226 SQQKDKQSYRDLKEVTPEGL 245



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 20/28 (71%), Positives = 25/28 (89%)
 Frame = -2

Query: 593 FFKDDANHDPQWSEEQIISAKFNYNGLL 510
           FFKDDAN+DPQWSEEQ+I+A F + GL+
Sbjct: 132 FFKDDANNDPQWSEEQLIAANFCFAGLV 159



 Score = 37.1 bits (82), Expect(2) = 0.046
 Identities = 18/31 (58%), Positives = 21/31 (67%)
 Frame = -3

Query: 94  RVTSAHKATEETLRIMQQYEDTHGALVFIAV 2
           RVTSAHK  +ETLRI  +YE      VF+AV
Sbjct: 273 RVTSAHKGPDETLRIKAEYEGDGIPTVFVAV 303



 Score = 22.2 bits (45), Expect(2) = 0.046
 Identities = 7/15 (46%), Positives = 12/15 (80%)
 Frame = -3

Query: 250 VKRNFAWVKDQLDFL 206
           VK+NF WV ++++ L
Sbjct: 248 VKKNFEWVAERVEVL 262


>UniRef50_A5UWC5 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=5; Chloroflexi (class)|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Roseiflexus sp. RS-1
          Length = 249

 Score =  117 bits (281), Expect = 3e-25
 Identities = 60/136 (44%), Positives = 82/136 (60%)
 Frame = -1

Query: 657 FLKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRK 478
           +++RNP V EG RF PP  E FL+   +   P +      +Q          DEV+ M  
Sbjct: 102 YIRRNPDVAEGTRFDPPLLEFFLKDDAR-HDPQMTPDEIIAQ-----GIASADEVEQMAS 155

Query: 477 ATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDK 298
            +  +F ++E+AWA +D  L D+KIEFG DT G +++ADVID+DSWR+WP G K  M+DK
Sbjct: 156 ESRRVFLLIEEAWAAQDVVLCDLKIEFGRDTSGRLLVADVIDNDSWRIWPGGVKERMLDK 215

Query: 297 QVYRNLTTVTAADLAQ 250
           QVYRN+  VT   L Q
Sbjct: 216 QVYRNMPVVTDEGLEQ 231


>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
           LOC431975 protein - Xenopus laevis (African clawed frog)
          Length = 371

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 48/121 (39%), Positives = 66/121 (54%), Gaps = 3/121 (2%)
 Frame = -1

Query: 669 CNWLFLKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSN--GRDE 496
           C  +   RN    EG+RF+ PK E +        S           ++L  +    G+ E
Sbjct: 175 CRKIPTGRNTETDEGYRFSQPKVEMYKVD---DTSNHQLSKEQLMAVKLICAGLLIGKME 231

Query: 495 VDYMRKATILIFEILEKAWALRDCALIDMKIEFGVD-TEGSIVLADVIDSDSWRLWPSGD 319
           VD M ++TI IFEI+EKAW  +DC L+DM+I+FGVD T+  I+L D I   S  LWP G+
Sbjct: 232 VDVMTRSTIAIFEIIEKAWRAQDCTLVDMRIKFGVDVTKKEILLTD-IKCGSQALWPLGN 290

Query: 318 K 316
           K
Sbjct: 291 K 291



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 22/51 (43%), Positives = 34/51 (66%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 35
           +VV+ M S +D  HC++I K+  + G+  +LRV SAH   +ETL I+ +YE
Sbjct: 305 RVVLLMESTSDLAHCEEIKKSCTKYGMKCELRVASAHTGPQETLDILAEYE 355


>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoribosylaminoimidazole
           succinocarboxamide synthetase; n=3; Archaea|Rep:
           Phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoribosylaminoimidazole
           succinocarboxamide synthetase - Methanosarcina barkeri
           (strain Fusaro / DSM 804)
          Length = 296

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 38/99 (38%), Positives = 59/99 (59%), Gaps = 7/99 (7%)
 Frame = -1

Query: 504 RDEVDYMRKATIL-IFEILEKAW-----ALRDCALIDMKIEFGVDTEGS-IVLADVIDSD 346
           ++E+DY+ +A +L  F  LE AW           L+D+KIE G   + + IV+ADVID+D
Sbjct: 195 QEELDYIVQAIMLPTFLALEDAWRKIMTTYGPMELVDLKIEVGRRLDNNRIVIADVIDND 254

Query: 345 SWRLWPSGDKRLMVDKQVYRNLTTVTAADLAQSNATLLG 229
           SWR+W  G+    +DKQ +R+   +    +A++ ATL G
Sbjct: 255 SWRIWSGGNPEKQLDKQCFRDGNPLD--QVAENYATLAG 291


>UniRef50_O57978 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pyrococcus horikoshii
          Length = 238

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 41/123 (33%), Positives = 63/123 (51%)
 Frame = -1

Query: 654 LKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKA 475
           LK+   +PEG+    P  E + +   +   PM+   N++    L  S    DE+  + + 
Sbjct: 100 LKKRLPLPEGYELPEPIVELYYKN-DELHDPMI---NYYHAKVLGISL---DEIKKIEEI 152

Query: 474 TILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQ 295
            + + EIL+   A +   L+D K+EFG D  G IVLAD I  D+ R W +  KR  +DK 
Sbjct: 153 ALKVNEILKDYLAKKGIILVDFKLEFGKDKNGDIVLADEISPDTCRFWDAKTKR-SLDKD 211

Query: 294 VYR 286
           V+R
Sbjct: 212 VFR 214


>UniRef50_Q5FIU8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
           n=6; Lactobacillus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamidesynthase
           - Lactobacillus acidophilus
          Length = 238

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
 Frame = -1

Query: 639 GVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKATILIF 460
           G+ EG +F  P +E F +   +   P++  ++  + + +  +   +   +  R+   L+ 
Sbjct: 104 GMGEGEKFDTPVEELFYKS-DELDDPIMNESDAIA-LHIATAEEQKKIWELSRQVNKLLI 161

Query: 459 EILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR-- 286
            + +KA       L+D K+EFG D +G+I+LAD    D+ RLW    K  M DK VYR  
Sbjct: 162 PLFDKA----GMELVDFKLEFGKDADGNIILADEFSPDNCRLWDKKTKEHM-DKDVYRRD 216

Query: 285 --NLTTVTAADLAQSNATL 235
             +LTTV   DLA+    L
Sbjct: 217 IGDLTTVYEQDLARIQEAL 235


>UniRef50_Q58987 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Euryarchaeota|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanococcus jannaschii
          Length = 242

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 26/73 (35%), Positives = 48/73 (65%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPS 325
           R+E++ +++  + + E+L+K +  +   L+D KIE G D EG++++AD I  D+ RLW  
Sbjct: 151 REELNKIKEIALKVNEVLKKLFDEKGIILVDFKIEIGKDREGNLLVADEISPDTMRLWDK 210

Query: 324 GDKRLMVDKQVYR 286
            + R ++DK V+R
Sbjct: 211 -ETRDVLDKDVFR 222


>UniRef50_A6QAA3 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=2; Epsilonproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Sulfurovum sp. (strain NBC37-1)
          Length = 244

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 28/71 (39%), Positives = 44/71 (61%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGD 319
           E+DY+R     I ++L+  +A R+  L+D K+EFG D +G+I+L D +  D++RLW S  
Sbjct: 153 ELDYIRYMARRINDLLKAFYAQRNLTLVDFKLEFGRDMDGNIILIDELSPDNFRLWDSVS 212

Query: 318 KRLMVDKQVYR 286
              M DK  +R
Sbjct: 213 GESM-DKDRFR 222


>UniRef50_Q92AN6 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=17; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Listeria innocua
          Length = 237

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/81 (39%), Positives = 49/81 (60%), Gaps = 4/81 (4%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           +E+D +R+A   I ++L++ +   +  LID K+EFG D  G+I+LAD I  D+ RLW   
Sbjct: 145 NEMDTIRQAARSINKVLQELFNQMNITLIDFKLEFGRDAAGNILLADEISPDTCRLWDK- 203

Query: 321 DKRLMVDKQVYR----NLTTV 271
           +    +DK V+R    NLT V
Sbjct: 204 ETNQKLDKDVFRRNIGNLTDV 224


>UniRef50_Q8TX83 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=6; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanopyrus kandleri
          Length = 247

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 25/72 (34%), Positives = 43/72 (59%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           +EV+ MR+ T+ + E+L +     D  L+D K+EFGV+ +G +V+ D I  D+ R W   
Sbjct: 147 EEVERMRELTLQVNEVLSEFLKDCDIILVDFKLEFGVNPDGEVVVGDEISPDTCRFW-DA 205

Query: 321 DKRLMVDKQVYR 286
           +    +DK ++R
Sbjct: 206 ETEESLDKDIFR 217


>UniRef50_P12046 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=61; Bacilli|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Bacillus subtilis
          Length = 241

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 29/81 (35%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           ++V+ ++  T ++ E L+  +      LID K+EFG+D EG ++LAD I  D+ RLW   
Sbjct: 148 EQVETIKSITTIVNEELQSIFDDCHVRLIDFKLEFGLDAEGQVLLADEISPDTCRLWDK- 206

Query: 321 DKRLMVDKQVY-RNLTTVTAA 262
           +    +DK ++ RNL ++T A
Sbjct: 207 ETNEKLDKDLFRRNLGSLTDA 227


>UniRef50_Q7M9X5 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=18; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Wolinella succinogenes
          Length = 236

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 27/75 (36%), Positives = 43/75 (57%)
 Frame = -1

Query: 510 NGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLW 331
           N ++E++++++    I EIL   +  +   L+D K+EFG D EG+I+LAD I  DS R W
Sbjct: 144 NSQEELEFLKETAREINEILRSFFDSKGLNLVDFKLEFGKDIEGNILLADEISPDSCRFW 203

Query: 330 PSGDKRLMVDKQVYR 286
                   +DK  +R
Sbjct: 204 DKKTNE-KLDKDRFR 217


>UniRef50_Q49WJ0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Staphylococcus saprophyticus subsp. saprophyticus
           (strain ATCC 15305 /DSM 20229)
          Length = 233

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 38/121 (31%), Positives = 59/121 (48%)
 Frame = -1

Query: 639 GVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKATILIF 460
           G  +G  F  P  E F +       P++   +H   +Q+  +++G  E++ +++A   I 
Sbjct: 103 GFEKGHTFETPLVEFFYKN-DDLNDPLIT-EDHIKLLQI--ANDG--EIEKLKEAATEIN 156

Query: 459 EILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNL 280
           E+L       +  L+D KIEFG   EG I+LAD I  D+ R+W         DK VYR  
Sbjct: 157 EVLVNLMDKMNLRLVDFKIEFGRTNEGEILLADEISPDTCRIWDK-QSDTNFDKDVYRED 215

Query: 279 T 277
           T
Sbjct: 216 T 216


>UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=1; Archaeoglobus fulgidus|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Archaeoglobus fulgidus
          Length = 180

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 23/61 (37%), Positives = 37/61 (60%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 8
           K V+ MGS +D ++ +KIA    + G+D  +R+ SAHK  E+ L I+++YE      V +
Sbjct: 28  KAVIIMGSKSDLDYSKKIASKLADFGIDAVMRIASAHKTPEKVLEIIKEYEKEDVVFVTV 87

Query: 7   A 5
           A
Sbjct: 88  A 88


>UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylase,
           PurE protein; n=1; Treponema denticola|Rep:
           Phosphoribosylaminoimidazole carboxylase, PurE protein -
           Treponema denticola
          Length = 159

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 19/61 (31%), Positives = 36/61 (59%)
 Frame = -3

Query: 184 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 5
           V++ MGS +D  H +KIA   +  G++  +R+ SAHK  E  + ++++YE      ++I 
Sbjct: 5   VIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSMLKEYEALDRPKLYIT 64

Query: 4   V 2
           +
Sbjct: 65  I 65


>UniRef50_P73471 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=19; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Synechocystis sp. (strain PCC 6803)
          Length = 264

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 4/79 (5%)
 Frame = -1

Query: 486 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGD---K 316
           ++   + I + L++ +A  D  L+D K+EFG D +G I+LAD I  D+ RLW +     +
Sbjct: 164 LKDLALNINQHLQRFFAQCDITLVDFKLEFGGDRQGKIILADEISPDTCRLWDNAQADPQ 223

Query: 315 RLMVDKQVY-RNLTTVTAA 262
             ++DK  + R+L ++ AA
Sbjct: 224 ARVLDKDRFRRDLGSIEAA 242


>UniRef50_Q6LZT3 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Methanococcus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanococcus maripaludis
          Length = 246

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/72 (33%), Positives = 42/72 (58%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           +E+  ++K  + + ++L+  +  +   L+D KIE G   +G IV+AD I  D+ RLW   
Sbjct: 155 EELVEIKKLALKVNDVLKGFFDEKGIMLVDFKIEVGKTADGQIVVADEISPDTMRLWDKE 214

Query: 321 DKRLMVDKQVYR 286
            K ++ DK V+R
Sbjct: 215 TKDVL-DKDVFR 225


>UniRef50_Q9X0X0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Thermotogaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Thermotoga maritima
          Length = 230

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 25/73 (34%), Positives = 44/73 (60%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPS 325
           + + + M++A + I   L++ +   +  L D+K EFG+D +G++VL D I  D++RL   
Sbjct: 138 KKQAEKMKEAAVKITLALKEFFERANFELWDIKYEFGLDKDGNVVLGDEISPDTFRLRKK 197

Query: 324 GDKRLMVDKQVYR 286
           G+   + DK VYR
Sbjct: 198 GE---IFDKDVYR 207


>UniRef50_A4SAQ9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ostreococcus lucimarinus CCE9901|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ostreococcus lucimarinus CCE9901
          Length = 367

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDS-DSWRLWP 328
           +D++DY    T+ +F   ++  A R   L+D K EFG D +G+I L D I++ DS R W 
Sbjct: 222 QDDLDYCVAKTLEVFAYAQEVAATRGLILVDTKYEFGRDADGTIRLIDEINTPDSSRYWL 281

Query: 327 S 325
           S
Sbjct: 282 S 282


>UniRef50_Q8G5A9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=5; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Bifidobacterium longum
          Length = 250

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
 Frame = -1

Query: 465 IFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGD---KRLMVDKQ 295
           I E L + +A  D  L+D KIE G  T+G+++LAD I  DS RLW   D   K   +DK 
Sbjct: 158 INEALIEIFAKIDVKLVDFKIEMGRATDGTLLLADEITPDSCRLWDQKDHSGKVEHLDKD 217

Query: 294 VYR 286
           ++R
Sbjct: 218 LFR 220


>UniRef50_Q4J8G0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Sulfolobaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Sulfolobus acidocaldarius
          Length = 235

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 33/123 (26%), Positives = 62/123 (50%)
 Frame = -1

Query: 654 LKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKA 475
           +KR P + EG  F PP  E FL+   +   P++    ++S +Q       R E + + + 
Sbjct: 100 VKRLP-IKEGEVFDPPIVEFFLKDDLR-HDPLL----NYSHLQYFNLLT-RKEAEIVEEV 152

Query: 474 TILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQ 295
            + +  +++     R   L D+K+EFG D + ++++ D I  DS R+      +++ DK 
Sbjct: 153 IVKVNAVMKNFLKERGLVLYDLKLEFGKDKDNNLIVGDEITLDSMRVRDEKTNKIL-DKD 211

Query: 294 VYR 286
           +YR
Sbjct: 212 LYR 214


>UniRef50_Q87Y59 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=12; Gammaproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pseudomonas syringae pv. tomato
          Length = 236

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 37/123 (30%), Positives = 56/123 (45%)
 Frame = -1

Query: 654 LKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKA 475
           L +  G+ EG +  P   E FL+   K   P +   +H             +++  M++ 
Sbjct: 101 LVKRLGIEEGTKLNPYTFELFLKDDAKG-DPFIN-ESHVVAF----GWGTAEQLVRMKEL 154

Query: 474 TILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQ 295
           +I + E+L K +      L+D K+EFGV   G IVL D    D  RLW   D R  +DK 
Sbjct: 155 SIKVNEVLTKLFDDAGLLLVDFKLEFGV-FHGEIVLGDEFSPDGCRLWDK-DTRKKMDKD 212

Query: 294 VYR 286
            +R
Sbjct: 213 RFR 215


>UniRef50_UPI00015BB105 Cluster:
           phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Ignicoccus hospitalis KIN4/I
          Length = 235

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 22/73 (30%), Positives = 41/73 (56%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPS 325
           +D +  +R+ T+ + E+L + +      LID K+E+G+  +G +VL D +  DS+R    
Sbjct: 140 KDVMKTIRETTLKVNELLTELFEKAGFKLIDFKVEYGITEDGRVVLIDELSPDSFRAHKG 199

Query: 324 GDKRLMVDKQVYR 286
           G+     DK ++R
Sbjct: 200 GE---AYDKDLFR 209


>UniRef50_A3H6Y2 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Caldivirga maquilingensis IC-167|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Caldivirga maquilingensis IC-167
          Length = 241

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/72 (31%), Positives = 44/72 (61%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           ++V  +R  ++ +  +L +        L+D K+EFGV++ G++VLAD +  D+ R+  +G
Sbjct: 148 EQVMEIRSVSLKVNHLLSELLGKYGLTLVDFKLEFGVNSNGALVLADELSGDTMRVLMNG 207

Query: 321 DKRLMVDKQVYR 286
            K L  DK+++R
Sbjct: 208 -KHL--DKELFR 216


>UniRef50_Q9RXT0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=37; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Deinococcus radiodurans
          Length = 237

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 26/72 (36%), Positives = 37/72 (51%)
 Frame = -1

Query: 501 DEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           D++  +R+  + I + L   +  R   LID K+EFG    G IVLAD I  D+ R W + 
Sbjct: 146 DDLKRIRELALQIRDFLVPYFEKRGVRLIDFKLEFGKLPSGEIVLADEISPDTCRFWDAE 205

Query: 321 DKRLMVDKQVYR 286
               M DK  +R
Sbjct: 206 TNEKM-DKDRFR 216


>UniRef50_Q3YRB0 Cluster: SAICAR synthetase; n=2;
           Anaplasmataceae|Rep: SAICAR synthetase - Ehrlichia canis
           (strain Jake)
          Length = 258

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGV---DTEGSIVLADVIDSDSWRLWP 328
           E++ ++  ++ I EIL + +      L+D K+EFG    +    ++LAD I  D+ RLW 
Sbjct: 156 ELEKIKMLSLKINEILSEIFLNVGIKLVDFKLEFGKLYNNKASDLLLADEISPDTCRLWN 215

Query: 327 SGDKRLMVDKQVYR-NLTTVTAA 262
             D R  +DK +YR NL  V  A
Sbjct: 216 ISDNR-KLDKDLYRMNLGNVIEA 237


>UniRef50_Q73PW0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Treponema denticola|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Treponema denticola
          Length = 316

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDS-DSWRLW 331
           +++ D+++KA + +FE  +K+       L+D K EFGVD   +I+L D + + DS R W
Sbjct: 172 KEQWDFVQKAALALFERGQKSAKEAGLILVDTKYEFGVDKNNNILLIDEVHTPDSSRYW 230


>UniRef50_Q8ES99 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=10; Firmicutes|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Oceanobacillus iheyensis
          Length = 237

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 32/121 (26%), Positives = 54/121 (44%)
 Frame = -1

Query: 639 GVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKATILIF 460
           G+ E   FTPP  E F +       P++   +      +  +     + D  R+    + 
Sbjct: 106 GIKEKVSFTPPLLELFYKD-DALGDPLINDEHALLLTDITETELAEIK-DKAREVNAALQ 163

Query: 459 EILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNL 280
           EI +         L+D K+EFG + +G I+L+D +  D+ RLW   +    +DK V+R  
Sbjct: 164 EIFQSI----GIKLVDFKLEFGRNKDGEILLSDEVSPDTCRLWDI-ETNEKLDKDVFRQG 218

Query: 279 T 277
           T
Sbjct: 219 T 219


>UniRef50_Q8TIS9 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=8; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Methanosarcina acetivorans
          Length = 237

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 26/73 (35%), Positives = 39/73 (53%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPS 325
           R+E+  +RK  + I E+L      +   L D K+EFG   +G I+L+D I  D+ R W  
Sbjct: 144 REELATLRKLALRINELLVPYLDEKGILLPDFKLEFG-RRDGEIILSDEISCDTCRFWDK 202

Query: 324 GDKRLMVDKQVYR 286
              + M DK V+R
Sbjct: 203 KTGQSM-DKDVFR 214


>UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 354

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 22/62 (35%), Positives = 33/62 (53%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 8
           KV++ +GS +D +  +K  K   ++ +  DLRV SAH+       IM  Y D  G  VFI
Sbjct: 19  KVMIILGSGSDYKIAEKTVKVFEQMKVPYDLRVASAHRTHNRIKDIMTNYVD--GIEVFI 76

Query: 7   AV 2
            +
Sbjct: 77  GI 78


>UniRef50_Q3WE59 Cluster: SAICAR synthetase; n=5; Bacteria|Rep:
           SAICAR synthetase - Frankia sp. EAN1pec
          Length = 354

 Score = 40.7 bits (91), Expect = 0.031
 Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
 Frame = -1

Query: 486 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRLWPS----- 325
           + + T+ IF       A R   L D K EFG D +G + LAD V+  DS R WP+     
Sbjct: 234 LERLTLQIFGRASDLAAERGILLADTKFEFGHDADGVLRLADEVLTPDSSRFWPADAWTP 293

Query: 324 GDKRLMVDKQVYRNLTTVTAAD 259
           G  +   DKQ  R+    T  D
Sbjct: 294 GGTQPSYDKQFIRDYLVSTGWD 315


>UniRef50_P0A7E0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=50; Proteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Shigella flexneri
          Length = 237

 Score = 40.7 bits (91), Expect = 0.031
 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 2/125 (1%)
 Frame = -1

Query: 654 LKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGA--NHFSQIQL*RSSNGRDEVDYMR 481
           L +  G+ EG    PP  + FL+       PMV  +    F  +        ++ +  M+
Sbjct: 101 LVKRLGIEEGIELNPPLFDLFLKN-DAMHDPMVNESYCETFGWVS-------KENLARMK 152

Query: 480 KATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVD 301
           + T    ++L+K +      L+D K+EFG+  +G +VL D    D  RLW       M D
Sbjct: 153 ELTYKANDVLKKLFDDAGLILVDFKLEFGL-YKGEVVLGDEFSPDGSRLWDKETLEKM-D 210

Query: 300 KQVYR 286
           K  +R
Sbjct: 211 KDRFR 215


>UniRef50_A7CZ13 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=1; Opitutaceae bacterium TAV2|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Opitutaceae bacterium TAV2
          Length = 306

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -1

Query: 492 DYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRLWPSG 322
           + ++ A++ ++ +     A     L D K EFG D  G++VL D ++  DS R WP+G
Sbjct: 194 EQVKAASLALYSLGHDKAARAGMILADTKFEFGTDAAGNLVLIDEILTPDSSRYWPAG 251


>UniRef50_Q7V5X1 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=15; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Prochlorococcus marinus (strain MIT 9313)
          Length = 242

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
 Frame = -1

Query: 516 SSNGRDEVDYM-RKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSW 340
           SS  R E++ + R+   L+    E      D  L+D K+E G+++ G++++AD I  D+ 
Sbjct: 146 SSQQRLEIEQLARRVNQLLLSFFESL----DLLLVDFKLELGLNSAGTLLVADEISPDTC 201

Query: 339 RLWP---SGDKRLMVDKQVYR 286
           RLW    S  +  ++DK  +R
Sbjct: 202 RLWDHRNSDPQARILDKDRFR 222


>UniRef50_Q88U22 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=3; Lactobacillales|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Lactobacillus plantarum
          Length = 243

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 23/67 (34%), Positives = 36/67 (53%)
 Frame = -1

Query: 486 MRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLM 307
           +++  + + + L   +A     L+D KIEFG+ T G ++LAD I  DS RL         
Sbjct: 155 IKRQALQVNQRLTAIFAAMGVQLVDFKIEFGLTTTGKVLLADEISPDSCRL-VDLKTGAS 213

Query: 306 VDKQVYR 286
           +DK V+R
Sbjct: 214 LDKDVFR 220


>UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole
           (NCAIR) mutase; n=1; Lawsonia intracellularis
           PHE/MN1-00|Rep: Phosphoribosylcarboxyaminoimidazole
           (NCAIR) mutase - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 171

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 20/62 (32%), Positives = 32/62 (51%)
 Frame = -3

Query: 193 HHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV 14
           H KV +F+GSP+D+       +   +L +     V+SAH+  E T  ++   E  +G  V
Sbjct: 3   HVKVAIFIGSPSDESIVSPCTEILTQLNIPYIFTVSSAHRTPERTAELIDSLE-ANGCEV 61

Query: 13  FI 8
           FI
Sbjct: 62  FI 63


>UniRef50_A0RW02 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR)
           synthase; n=1; Cenarchaeum symbiosum|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR)
           synthase - Cenarchaeum symbiosum
          Length = 273

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPS-- 325
           E D++   +I ++  +  A       L D+K+EFG    GSI L D I  D  RLWP+  
Sbjct: 148 EYDWLSAKSIEVYNAMSVAAEAAGFVLADVKLEFG-RLGGSITLGDSIGPDECRLWPAEQ 206

Query: 324 ---GDKRLMVDKQVYRN 283
              G  +   DKQ+ R+
Sbjct: 207 YSPGAIQEAFDKQILRD 223


>UniRef50_Q8ZCD2 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=17; Enterobacteriaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Yersinia pestis
          Length = 237

 Score = 39.5 bits (88), Expect = 0.072
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 2/125 (1%)
 Frame = -1

Query: 654 LKRNPGVPEGFRFTPPKQETFLQG*RKPRSPMVRGANHFSQIQL*RSSNGRDEVDYMRKA 475
           L +  G+ EG    PP  + FL+       PMV  +   +      +   R     M++ 
Sbjct: 101 LVKRLGIEEGLSLNPPLFDLFLKN-DAMHDPMVNESYCKTFGWATEAQLAR-----MKEL 154

Query: 474 TILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLM--VD 301
           + L  ++L K +      L+D K+EFG+   G +VL D    D  RLW   DK+ +  +D
Sbjct: 155 SYLANDVLSKLFDDAGLILVDFKLEFGL-FNGEVVLGDEFSPDGSRLW---DKKTLNKMD 210

Query: 300 KQVYR 286
           K  YR
Sbjct: 211 KDRYR 215


>UniRef50_Q03Y92 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase; n=4; Lactobacillales|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 249

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 18/45 (40%), Positives = 29/45 (64%)
 Frame = -1

Query: 420 LIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR 286
           L+D K+E+G D+EG ++LAD +  D+ RL      +  +DK V+R
Sbjct: 184 LVDFKLEYGRDSEGKLILADELSPDNMRLVDQKTGK-SLDKDVFR 227


>UniRef50_Q7UJ19 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=2; Planctomycetaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Rhodopirellula baltica
          Length = 320

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
 Frame = -1

Query: 513 SNGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWR 337
           S G ++   +R+ ++ I++   K  A R   + D K EFGV  +G ++L D V+  DS R
Sbjct: 198 SLGEEQSSQLRRMSLAIYQDASKIAAERGLLIADTKFEFGV-VDGELMLIDEVLTPDSSR 256

Query: 336 LWPS-----GDKRLMVDKQVYR 286
            W +     G  +   DKQ  R
Sbjct: 257 FWAADEYEPGHSQRSFDKQFVR 278


>UniRef50_Q7VAN8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=9; Prochlorococcus marinus|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Prochlorococcus marinus
          Length = 244

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 19/62 (30%), Positives = 36/62 (58%)
 Frame = -1

Query: 516 SSNGRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWR 337
           SS+ R E+   ++ ++ + + L++     D  L+D K+E G +  G +++AD I  DS R
Sbjct: 146 SSSQRKEI---QRLSLRVNDCLKEFMKGLDLLLVDFKLEMGFNGSGQLLIADEISPDSCR 202

Query: 336 LW 331
           +W
Sbjct: 203 IW 204


>UniRef50_Q648Z8 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=1; uncultured archaeon GZfos35D7|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - uncultured archaeon GZfos35D7
          Length = 249

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 7/78 (8%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGS--IVLADVIDS-DSWRLW- 331
           E+D +R+ T L  EI+ +    R   L D KIEFG D   +  I+LAD + + D  R W 
Sbjct: 153 ELDSIRECTRLTNEIMSERLLKRGIILADFKIEFGRDKNAAEKILLADEVGTPDGCRFWD 212

Query: 330 -PSGDKRLM--VDKQVYR 286
             + ++ ++  +DK VYR
Sbjct: 213 RDAYEQGVIESLDKDVYR 230


>UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=9; Proteobacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Coxiella burnetii
          Length = 166

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 18/60 (30%), Positives = 30/60 (50%)
 Frame = -3

Query: 184 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 5
           V + MGS +D    +      + LG+  +  + SAH+  +ET+  ++   D  G  VFIA
Sbjct: 6   VAILMGSDSDLSTMETAFTELKSLGIPFEAHILSAHRTPKETVEFVEN-ADNRGCAVFIA 64


>UniRef50_Q1IPE1 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=7; Bacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 318

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 17/60 (28%), Positives = 31/60 (51%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWP 328
           G D  + +R+ +I I++        +   + D K EFG+  +G ++  +V+  DS R WP
Sbjct: 198 GGDLSEKLREVSIKIYKAAADYALTKGIIIADTKFEFGMTPKGLVLADEVLTPDSSRFWP 257


>UniRef50_Q8ZZK5 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Pyrobaculum|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pyrobaculum aerophilum
          Length = 234

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 22/76 (28%), Positives = 37/76 (48%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSGD 319
           EV+ + +  +     L   +A   C  ID+K EFG    G ++L D +  D++RL   G+
Sbjct: 142 EVEAIEEMAVRAASALRDLYARAGCDFIDVKFEFG-RRGGRLILVDEVSGDTFRLLCRGE 200

Query: 318 KRLMVDKQVYRNLTTV 271
               +DK+ +R    V
Sbjct: 201 H---LDKEYFRKTKDV 213


>UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole
           carboxylase; n=2; Methanothermobacter thermautotrophicus
           str. Delta H|Rep: Probable phosphoribosylaminoimidazole
           carboxylase - Methanobacterium thermoautotrophicum
          Length = 334

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 8
           +V++ +GS +D    +K  +   EL +  DLRV SAH+  E+   I+ +     G  VFI
Sbjct: 4   RVMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVKA-GVEVFI 62

Query: 7   AV 2
            +
Sbjct: 63  GI 64


>UniRef50_Q1MRH1 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase; n=7; Proteobacteria|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR)
           synthase - Lawsonia intracellularis (strain PHE/MN1-00)
          Length = 298

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIFEILEKAWAL-RDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRL 334
           G+D    +   ++L+F      WA  R   + D K EFG+  +G ++L D V+  DS R 
Sbjct: 177 GKDTTTLVASLSLLMFNEAS-VWAEDRGIIIADTKFEFGI-LDGQVILIDEVLTPDSSRF 234

Query: 333 WPS-----GDKRLMVDKQVYRN 283
           WP+     G  +   DKQ  R+
Sbjct: 235 WPTKNYIPGKSQPSFDKQYLRD 256


>UniRef50_P43060 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=11; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Candida albicans (Yeast)
          Length = 291

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 18/73 (24%), Positives = 36/73 (49%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWP 328
           G++  D + K  I ++       A +   + D K EFG+D +  +++ +V+  DS R W 
Sbjct: 171 GKELCDRIEKIAIDLYTKARDYAATKGIIIADTKFEFGLDGDKIVLVDEVLTPDSSRFWS 230

Query: 327 SGDKRLMVDKQVY 289
           +   +L   ++ Y
Sbjct: 231 AAKYKLGQSQESY 243


>UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=11; Clostridium|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Clostridium perfringens
          Length = 159

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 8
           KV +F GS +D +  +    A +E G+  +  + SAH+  E+ +  +++ E   G  V I
Sbjct: 2   KVAIFFGSKSDIDVMKGAGNALKEFGIPYNAYILSAHRVPEKLIETLEKIE-KEGCEVII 60

Query: 7   A 5
           A
Sbjct: 61  A 61


>UniRef50_Q5JD27 Cluster:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
           n=1; Thermococcus kodakarensis KOD1|Rep:
           Phosphoribosylaminoimidazolesuccinocarboxamide synthase
           - Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
          Length = 219

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 18/59 (30%), Positives = 33/59 (55%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWPSG 322
           EV  M++ T  + EIL + ++ +   L+D K+EFG    G +++ D +  D+ R+   G
Sbjct: 149 EVREMKEKTRKVAEILREFFSSKGLQLVDFKLEFG-RRNGELIVIDELSGDTMRVIKDG 206


>UniRef50_P38025 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase, chloroplast precursor; n=13; cellular
           organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase, chloroplast precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 411

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
 Frame = -1

Query: 498 EVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDS-DSWRLWPSG 322
           E D      + +FE  +         L+D K EFG  ++GSI+L D I + DS R W +G
Sbjct: 262 EFDEASMKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSRYWLAG 321


>UniRef50_Q98I23 Cluster: Putative
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           2; n=16; Alphaproteobacteria|Rep: Putative
           phosphoribosylaminoimidazole-succinocarboxamide synthase
           2 - Rhizobium loti (Mesorhizobium loti)
          Length = 313

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 19/37 (51%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
 Frame = -1

Query: 438 ALRDCALIDMKIEFGVDTEGSIVLADVIDS-DSWRLW 331
           A R   L D K EFG D  G+I+LAD I + DS R W
Sbjct: 191 AERGLILADTKYEFGTDKNGTIILADEIHTPDSSRYW 227


>UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=5; Bacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Geobacter uraniumreducens Rf4
          Length = 168

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 19/61 (31%), Positives = 33/61 (54%)
 Frame = -3

Query: 187 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 8
           +V++ MGS +D     + AK   E  +  ++R++SAH++   T  +  + ED  G  V I
Sbjct: 5   QVLIVMGSDSDLPVMGEAAKVLTEFDVPFEMRISSAHRSPRRTGLLASEAED-RGVKVVI 63

Query: 7   A 5
           A
Sbjct: 64  A 64


>UniRef50_Q9C1J4 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=14; cellular organisms|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Pichia pastoris (Yeast)
          Length = 304

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDSWRLW 331
           G+D  + +    + ++   +    L+   + D K EFG+D    +VL D V+  DS R W
Sbjct: 184 GKDICEKVAVKAVELYSAAKNFALLKGIIIADTKFEFGLDENNELVLVDEVLTPDSSRFW 243

Query: 330 PS-----GDKRLMVDKQVYRNLTT 274
                  G  +   DKQ  R+  T
Sbjct: 244 NQKTYQVGKSQESYDKQFLRDWLT 267


>UniRef50_A0Q508 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=14; Gammaproteobacteria|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Francisella tularensis subsp. novicida (strain U112)
          Length = 770

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = -1

Query: 492 DYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTE-GSIVLADVIDS-DSWRLW 331
           D+  +  + +FE  +K        L D K EFG+D + G I+L D I + DS R W
Sbjct: 180 DFASQKALELFEFGQKKALEHGLILADTKYEFGIDEQTGEIILIDEIHTPDSSRFW 235


>UniRef50_Q4UML8 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=8; Rickettsia|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Rickettsia felis (Rickettsia azadi)
          Length = 236

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
 Frame = -1

Query: 504 RDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFG---VDTEGSIVLADVIDSDSWRL 334
           RDE+  +++  + I++ L   +      L++ K+EFG      E  I+L D I  D+ RL
Sbjct: 142 RDEIKAVKEQALRIYDFLSGLFIGVGIRLVECKLEFGRVFNGEESIIMLTDEISPDNCRL 201

Query: 333 W 331
           W
Sbjct: 202 W 202


>UniRef50_Q8F0I0 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=4; Leptospira|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Leptospira interrogans
          Length = 285

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIF----EILEKAWALRDCALIDMKIEFGVDTEGSIVLAD-VIDSDS 343
           G++  + +++ +I IF    E+++KA  +    L D K EFG+  +G ++L D ++  DS
Sbjct: 162 GKELFNILKEKSISIFLRASEVVDKAGII----LCDTKFEFGI-LDGQVILIDELLTPDS 216

Query: 342 WRLWPS-----GDKRLMVDKQVYRNLTTVTA 265
            R W +     G     +DKQ+ RN    T+
Sbjct: 217 SRYWSTDTYSVGISPPSLDKQILRNYLETTS 247


>UniRef50_Q3Z881 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Dehalococcoides ethenogenes 195|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Dehalococcoides ethenogenes (strain 195)
          Length = 304

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
 Frame = -1

Query: 507 GRDEVDYMRKATILIFEILEKAWALRDCALIDMKIEFGVDTEGSIVLADVIDSDSWRLWP 328
           G++  D + + ++ ++++  +    R   + D K EFG+D    I++ + +  DS R W 
Sbjct: 184 GKELADKLAEKSLALYKLGREYARQRGIIIADTKFEFGLDGSELILIDEALTPDSSRFWD 243

Query: 327 S-----GDKRLMVDKQVYRN 283
                 G+ +   DKQ  R+
Sbjct: 244 EKTYRVGEAQDSYDKQPVRD 263


>UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: PqqE
           homolog - Aeropyrum pernix
          Length = 389

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = -3

Query: 238 FAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEET 59
           F++V   LD + P +H K   F G+P   +   + A+ A E GLDV  R+T      ++ 
Sbjct: 135 FSYVGISLDSVDPGVHDK---FRGAPGAFKAAIRGARNALEEGLDVGFRLTITKYNLDDA 191

Query: 58  LRIMQQYED 32
            RI++   D
Sbjct: 192 PRIIRLASD 200


>UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n=7;
           Bacteroidales|Rep: Indole-3-glycerol phosphate synthase
           - Bacteroides thetaiotaomicron
          Length = 260

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 15/36 (41%), Positives = 24/36 (66%)
 Frame = -3

Query: 181 VVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHK 74
           V+ + +   QE CQ++A+ A ELGL+V L + SA +
Sbjct: 137 VLLIAAALKQEKCQELAEQAHELGLEVLLEIHSAEE 172


>UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE
           CATALYTIC SUBUNIT; n=19; delta/epsilon subdivisions|Rep:
           PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC
           SUBUNIT - Wolinella succinogenes
          Length = 164

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 18/60 (30%), Positives = 34/60 (56%)
 Frame = -3

Query: 184 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 5
           V + MGS +D E  ++ A+  ++  +  ++ ++SAH++   T   + + E   GA VFIA
Sbjct: 4   VSILMGSKSDAEVMRECAEIFKKFDVPYEMIISSAHRSPVRTKEYVLEAE-ARGAKVFIA 62


>UniRef50_Q2UIJ7 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 210

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 20/76 (26%), Positives = 33/76 (43%)
 Frame = +2

Query: 194 DRRLQEIKLVFHPSKVAFDCARSAAVTVVRFRYTCLSTINLLSPEGHNLQESESMTSANT 373
           DR   +   + H  K    C +S A TV++  ++   +I LL+P+GH      S+     
Sbjct: 75  DRCWYQCSRMLHLPKSTRQCLQSVATTVLKVGHSIQFSITLLNPDGHLSSIRLSLPIVII 134

Query: 374 MLPSVSTPNSIFMSIS 421
             PS S    +   I+
Sbjct: 135 FYPSTSASLQMLSDIA 150


>UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylase;
           n=5; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 169

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 17/61 (27%), Positives = 30/61 (49%)
 Frame = -3

Query: 184 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 5
           VV+ +GS +D+E  +K  +     G++  + V SAH+       I++    T     FIA
Sbjct: 4   VVIILGSKSDKEVARKATEVFDRFGIEYTITVASAHRTPARLAEIIETAHKT-DVKAFIA 62

Query: 4   V 2
           +
Sbjct: 63  I 63


>UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium
           japonicum|Rep: Blr6315 protein - Bradyrhizobium
           japonicum
          Length = 790

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 15/41 (36%), Positives = 25/41 (60%)
 Frame = -3

Query: 157 DQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 35
           ++E  +++A+   + G D+D +   A KA+EE LRI Q  E
Sbjct: 563 ERERAEQLARDLAKAGRDLDAQTERASKASEEVLRIKQAGE 603


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 707,785,644
Number of Sequences: 1657284
Number of extensions: 14646370
Number of successful extensions: 35229
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 34175
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35213
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51652897375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -