Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbVm1272
(768 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P30566 Cluster: Adenylosuccinate lyase; n=74; cellular ... 146 7e-34
UniRef50_Q6GLC2 Cluster: Adenylosuccinate lyase; n=13; cellular ... 143 5e-33
UniRef50_Q97I33 Cluster: Adenylosuccinate lyase; n=32; cellular ... 95 1e-18
UniRef50_A6G4E8 Cluster: Adenylosuccinate lyase; n=2; Bacteria|R... 93 9e-18
UniRef50_Q6QNT8 Cluster: Adenylosuccinate lyase; n=6; Borrelia|R... 78 3e-13
UniRef50_Q21774 Cluster: Adenylosuccinate lyase; n=3; Caenorhabd... 44 0.006
UniRef50_Q9UZ99 Cluster: Adenylosuccinate lyase; n=11; Euryarcha... 38 0.36
UniRef50_Q3AZP0 Cluster: Adenylosuccinate lyase; n=41; Bacteria|... 35 1.9
UniRef50_Q3AHI4 Cluster: Adenylosuccinate lyase; n=3; Bacteria|R... 35 1.9
UniRef50_P74384 Cluster: Adenylosuccinate lyase; n=37; Bacteria|... 35 1.9
UniRef50_Q46EP0 Cluster: Adenylosuccinate lyase; n=6; Methanomic... 34 4.5
UniRef50_O66856 Cluster: Adenylosuccinate lyase; n=65; cellular ... 33 5.9
UniRef50_UPI00015BD1D1 Cluster: UPI00015BD1D1 related cluster; n... 33 7.8
UniRef50_A6CPJ0 Cluster: Sensory box/GGDEF family protein; n=1; ... 33 7.8
>UniRef50_P30566 Cluster: Adenylosuccinate lyase; n=74; cellular
organisms|Rep: Adenylosuccinate lyase - Homo sapiens
(Human)
Length = 484
Score = 146 bits (353), Expect = 7e-34
Identities = 90/187 (48%), Positives = 112/187 (59%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSERCA------L*PVI*LLYT*RS*YSCRPMVRTNPRRLCQSSHY 170
QIGSSAMPYKRNPMRSERC + V+ L T + R + + RR+C + +
Sbjct: 286 QIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAF 345
Query: 171 PRRGFPY*RYSTDTIKYLPRPGGVSESDARHIAQELPFMATENIIMAMVQAGGDRQVCHE 350
+ + P + R I QELPFMATENIIMAMV+AGG RQ CHE
Sbjct: 346 LTADTILNTLQNISEGLVVYPKVIE----RRIRQELPFMATENIIMAMVKAGGSRQDCHE 401
Query: 351 KIRVLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLDKILDASTFIGRAPNKWTSFW 530
KIRVLS +A + VKQ G DNDLIER++ D YF+PI SQLD +LD S+F GRA + F
Sbjct: 402 KIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFL 461
Query: 531 MKKSIPL 551
++ PL
Sbjct: 462 EEEVYPL 468
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/49 (53%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +1
Query: 112 THAVQWLERTLDDSANRRI-XXXXXXXXXXXXXXXXNICQGLVVYPKVM 255
T +VQW ERTLDDSANRRI NI +GLVVYPKV+
Sbjct: 321 TASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVI 369
>UniRef50_Q6GLC2 Cluster: Adenylosuccinate lyase; n=13; cellular
organisms|Rep: Adenylosuccinate lyase - Xenopus
tropicalis (Western clawed frog) (Silurana tropicalis)
Length = 503
Score = 143 bits (346), Expect = 5e-33
Identities = 86/187 (45%), Positives = 112/187 (59%), Gaps = 6/187 (3%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSERCA------L*PVI*LLYT*RS*YSCRPMVRTNPRRLCQSSHY 170
QIGSSAMPYKRNPMRSERC + ++ L T + R + + RR+C + +
Sbjct: 305 QIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANRRVCLAEAF 364
Query: 171 PRRGFPY*RYSTDTIKYLPRPGGVSESDARHIAQELPFMATENIIMAMVQAGGDRQVCHE 350
+ + P + R I QELPFMATENIIMAMV+ GG+RQ CHE
Sbjct: 365 LTADIILSTLQNISEGLVVYPKVIE----RRIRQELPFMATENIIMAMVKNGGNRQDCHE 420
Query: 351 KIRVLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLDKILDASTFIGRAPNKWTSFW 530
+IRVLS +A A VKQ G DNDLI R++ D YFAPI + L+++LD +F GRAP + F
Sbjct: 421 RIRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVLKFL 480
Query: 531 MKKSIPL 551
++ IPL
Sbjct: 481 KEEVIPL 487
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/53 (49%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +1
Query: 100 NAANTHAVQWLERTLDDSANRRI-XXXXXXXXXXXXXXXXNICQGLVVYPKVM 255
N T +VQW ERTLDDSANRR+ NI +GLVVYPKV+
Sbjct: 336 NPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVI 388
>UniRef50_Q97I33 Cluster: Adenylosuccinate lyase; n=32; cellular
organisms|Rep: Adenylosuccinate lyase - Clostridium
acetobutylicum
Length = 476
Score = 95.5 bits (227), Expect = 1e-18
Identities = 44/83 (53%), Positives = 57/83 (68%)
Frame = +3
Query: 261 HIAQELPFMATENIIMAMVQAGGDRQVCHEKIRVLSHEAGAQVKQHGRDNDLIERVKKDG 440
H+ ELPFMATENI+M V+ G DRQ HE+IR S E ++K G NDLIER+KKD
Sbjct: 364 HVKSELPFMATENIMMEAVKKGCDRQELHERIRKHSMETAKRIKADGLPNDLIERIKKDS 423
Query: 441 YFAPIISQLDKILDASTFIGRAP 509
YF ++D+I+D + F+GRAP
Sbjct: 424 YFKLTEKEIDEIIDPNKFVGRAP 446
Score = 39.9 bits (89), Expect = 0.068
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Frame = +1
Query: 67 RSSPSSNYFTRNAAN---THAVQWLERTLDDSANRRI-XXXXXXXXXXXXXXXXNICQGL 234
R S S Y N+ N T A QW ERTLDDSAN+RI N+ +
Sbjct: 295 RISALSRYIIVNSLNPAITAATQWFERTLDDSANKRISVAEAFLALDGVLNLYINVSSNM 354
Query: 235 VVYPKVM 255
VVY V+
Sbjct: 355 VVYENVI 361
Score = 38.7 bits (86), Expect = 0.16
Identities = 17/19 (89%), Positives = 18/19 (94%)
Frame = +3
Query: 6 SQIGSSAMPYKRNPMRSER 62
+QIGSSAM YKRNPMRSER
Sbjct: 277 NQIGSSAMAYKRNPMRSER 295
>UniRef50_A6G4E8 Cluster: Adenylosuccinate lyase; n=2; Bacteria|Rep:
Adenylosuccinate lyase - Plesiocystis pacifica SIR-1
Length = 479
Score = 92.7 bits (220), Expect = 9e-18
Identities = 73/174 (41%), Positives = 96/174 (55%), Gaps = 7/174 (4%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSERC-AL*PVI*LLYT*-RS*YSCRPMVRTNPRRLCQSSHYPRRG 182
QIGSSAM YKRNPMRSER AL + L T R + + + RT S R
Sbjct: 284 QIGSSAMAYKRNPMRSERINALARFVHSLATSPRETHGNQWLERT-----LDDSANRRLV 338
Query: 183 FPY*RYSTDTIKYL--PRPGGVSESDA---RHIAQELPFMATENIIMAMVQAGGDRQVCH 347
+TD I L G+ + A +++A ELPFMATEN++M V+AGGDRQ H
Sbjct: 339 ITEAFLATDAILNLVVDVTAGIVVNPAMLAKNMADELPFMATENVLMRAVEAGGDRQALH 398
Query: 348 EKIRVLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLDKILDASTFIGRAP 509
E IR LS A ++K GR NDL+ R+++D P + LDAS ++GR+P
Sbjct: 399 ETIRQLSIAAAGELKA-GRGNDLMARMQEDPELGPHVDA--GALDASRYVGRSP 449
Score = 39.1 bits (87), Expect = 0.12
Identities = 16/19 (84%), Positives = 17/19 (89%)
Frame = +1
Query: 112 THAVQWLERTLDDSANRRI 168
TH QWLERTLDDSANRR+
Sbjct: 319 THGNQWLERTLDDSANRRL 337
>UniRef50_Q6QNT8 Cluster: Adenylosuccinate lyase; n=6; Borrelia|Rep:
Adenylosuccinate lyase - Borrelia miyamotoi
Length = 467
Score = 77.8 bits (183), Expect = 3e-13
Identities = 55/169 (32%), Positives = 83/169 (49%), Gaps = 2/169 (1%)
Frame = +3
Query: 6 SQIGSSAMPYKRNPMRSERCA-L*PVI*LLYT*RS*YSCRPMV-RTNPRRLCQSSHYPRR 179
+QIGSSAMPYKRNP+ SER A L I L + + + RT C+ + P+
Sbjct: 277 NQIGSSAMPYKRNPIYSERVASLAKFIMSLQSSGGFIAATQWLERTLDDSACKRINIPQA 336
Query: 180 GFPY*RYSTDTIKYLPRPGGVSESDARHIAQELPFMATENIIMAMVQAGGDRQVCHEKIR 359
K +H+ +E+PF+ TE+I+M + GGDRQ+ HEKIR
Sbjct: 337 FLAADAILILLNKIFNNIRVNKTIIEKHVKKEIPFILTEDILMKATKNGGDRQILHEKIR 396
Query: 360 VLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLDKILDASTFIGRA 506
+ S + + +NDLI+ + D F +D++L+ + IG A
Sbjct: 397 IYSMQVRENLTSKTTENDLIKLILNDESFKLTPKDIDEVLNPNENIGFA 445
>UniRef50_Q21774 Cluster: Adenylosuccinate lyase; n=3;
Caenorhabditis|Rep: Adenylosuccinate lyase -
Caenorhabditis elegans
Length = 478
Score = 43.6 bits (98), Expect = 0.006
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 6/186 (3%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSERCAL*PVI*LLYT*RS*YSCRPMVRTNPRRLCQSSHYPRRGFP 188
QIGSSAMPYK+NPM+SERC + + + R S R P
Sbjct: 282 QIGSSAMPYKKNPMKSERCC---ALSRKLINAPQEALTILADQGLERTLDDSAGRRMLIP 338
Query: 189 Y*RYSTD----TIKYLPRPGGVSESDARHIAQ-ELPFMATENIIMAMVQAGGDRQVCHEK 353
+ + T++ + V + + I + E+ F+ E +M + + G DRQ H
Sbjct: 339 DVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFLGLEKAMMMLTEEGVDRQQAHAV 398
Query: 354 IRVLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLDKIL-DASTFIGRAPNKWTSFW 530
IR + EA D I + D +F + ++ ++ + F GR ++ SF
Sbjct: 399 IRKTALEAKQLQATQKVD---IRQTMADPFFDSVRDRVVGLVNNPINFTGRCVSQTESFI 455
Query: 531 MKKSIP 548
K+ P
Sbjct: 456 AKELKP 461
>UniRef50_Q9UZ99 Cluster: Adenylosuccinate lyase; n=11;
Euryarchaeota|Rep: Adenylosuccinate lyase - Pyrococcus
abyssi
Length = 450
Score = 37.5 bits (83), Expect = 0.36
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 10/176 (5%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER-CAL*PVI*LLYT*RS*YSCRPMVRTNP---RRLCQSSHYPR 176
Q+GSS MP+KRNP+R+E+ C L V LY+ + P + NP R +S R
Sbjct: 270 QVGSSTMPHKRNPIRTEKVCGLARV---LYS-----NVIPALLNNPLWHERDLTNSSVER 321
Query: 177 RGFPY*RYSTDTI-----KYLPRPGGVSESDARHIAQELPFMATENIIMAMVQAGGDRQV 341
P D + K L E+ R++ + E +++ + + G RQ
Sbjct: 322 VILPESFVLLDEMLKVMKKVLKGLEFFPENIKRNLYLTKNLIMAEPLMLKLAEKGMGRQE 381
Query: 342 CHEKIRVLSHEAGAQVKQHGRDNDLIERVKKDGYFAPIISQLD-KILDASTFIGRA 506
HE +R L+ +A + GR DL+E V+K+ +++ D + L +IG+A
Sbjct: 382 AHELVRQLAMKA----FKEGR--DLLEVVRKNEEAMKYLTENDLEGLKPENYIGKA 431
>UniRef50_Q3AZP0 Cluster: Adenylosuccinate lyase; n=41;
Bacteria|Rep: Adenylosuccinate lyase - Synechococcus sp.
(strain CC9902)
Length = 431
Score = 35.1 bits (77), Expect = 1.9
Identities = 15/18 (83%), Positives = 17/18 (94%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER 62
Q GSSAMP+KRNP+RSER
Sbjct: 259 QKGSSAMPHKRNPIRSER 276
>UniRef50_Q3AHI4 Cluster: Adenylosuccinate lyase; n=3; Bacteria|Rep:
Adenylosuccinate lyase - Synechococcus sp. (strain
CC9605)
Length = 431
Score = 35.1 bits (77), Expect = 1.9
Identities = 15/18 (83%), Positives = 17/18 (94%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER 62
Q GSSAMP+KRNP+RSER
Sbjct: 259 QKGSSAMPHKRNPIRSER 276
>UniRef50_P74384 Cluster: Adenylosuccinate lyase; n=37;
Bacteria|Rep: Adenylosuccinate lyase - Synechocystis sp.
(strain PCC 6803)
Length = 431
Score = 35.1 bits (77), Expect = 1.9
Identities = 15/18 (83%), Positives = 17/18 (94%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER 62
Q GSSAMP+KRNP+RSER
Sbjct: 259 QKGSSAMPHKRNPIRSER 276
>UniRef50_Q46EP0 Cluster: Adenylosuccinate lyase; n=6;
Methanomicrobia|Rep: Adenylosuccinate lyase -
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length = 448
Score = 33.9 bits (74), Expect = 4.5
Identities = 14/22 (63%), Positives = 19/22 (86%), Gaps = 1/22 (4%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER-CAL 71
Q+GSS MP+KRNP++SE+ C L
Sbjct: 269 QVGSSTMPHKRNPIKSEQMCGL 290
>UniRef50_O66856 Cluster: Adenylosuccinate lyase; n=65; cellular
organisms|Rep: Adenylosuccinate lyase - Aquifex aeolicus
Length = 437
Score = 33.5 bits (73), Expect = 5.9
Identities = 17/26 (65%), Positives = 20/26 (76%), Gaps = 1/26 (3%)
Frame = +3
Query: 9 QIGSSAMPYKRNPMRSER-CAL*PVI 83
Q GSSAMP+K+NP+ SER C L VI
Sbjct: 262 QRGSSAMPHKKNPIHSERICGLARVI 287
>UniRef50_UPI00015BD1D1 Cluster: UPI00015BD1D1 related cluster; n=1;
unknown|Rep: UPI00015BD1D1 UniRef100 entry - unknown
Length = 433
Score = 33.1 bits (72), Expect = 7.8
Identities = 15/23 (65%), Positives = 19/23 (82%), Gaps = 1/23 (4%)
Frame = +3
Query: 6 SQIGSSAMPYKRNPMRSER-CAL 71
SQ GSSAMP+K+NP+ +ER C L
Sbjct: 261 SQRGSSAMPHKKNPIHAERICGL 283
>UniRef50_A6CPJ0 Cluster: Sensory box/GGDEF family protein; n=1;
Bacillus sp. SG-1|Rep: Sensory box/GGDEF family protein
- Bacillus sp. SG-1
Length = 793
Score = 33.1 bits (72), Expect = 7.8
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Frame = +3
Query: 327 GDRQVCHEKIRVLSH-EAGAQVKQHGRDND--LIERVKKDGYFAPIISQLDKILDASTFI 497
GDR + +R+LS G+ V + G D L+ RV + F P + QL KILD S F+
Sbjct: 422 GDRVLKELSLRLLSVLPDGSVVSRFGGDEIYCLVPRVDGNNEFEPALEQLYKILDTSFFV 481
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 695,031,813
Number of Sequences: 1657284
Number of extensions: 13136829
Number of successful extensions: 30234
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 29362
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30220
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 64204279620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -