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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbVm0826
         (516 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to 2-oxoisova...   110   2e-23
UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit ...   110   2e-23
UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2; ...    78   1e-13
UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18; ce...    73   3e-12
UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit ...    70   4e-11
UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular ...    65   8e-10
UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component bet...    63   3e-09
UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1; ...    56   4e-07
UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1, tran...    55   8e-07
UniRef50_A0JY24 Cluster: Transketolase, central region; n=2; cel...    52   8e-06
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot...    52   1e-05
UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component sub...    51   2e-05
UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta sub...    50   2e-05
UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) b...    48   1e-04
UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent dehydr...    48   1e-04
UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component sub...    48   1e-04
UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit ...    48   2e-04
UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, be...    47   2e-04
UniRef50_A6UDY4 Cluster: Transketolase central region; n=1; Sino...    47   3e-04
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub...    46   5e-04
UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1; Synt...    46   7e-04
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase...    45   9e-04
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter...    45   9e-04
UniRef50_A5UU14 Cluster: Transketolase, central region; n=3; Chl...    45   9e-04
UniRef50_A0CTB9 Cluster: Chromosome undetermined scaffold_27, wh...    45   0.001
UniRef50_A5V352 Cluster: Transketolase, central region; n=1; Sph...    44   0.002
UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=...    44   0.002
UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, be...    44   0.003
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;...    44   0.003
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter...    43   0.004
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo...    43   0.004
UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component sub...    42   0.006
UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component sub...    42   0.006
UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit ...    42   0.008
UniRef50_Q479Q1 Cluster: Transketolase, central region:Transketo...    42   0.011
UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c...    42   0.011
UniRef50_A7CXF2 Cluster: Transketolase central region; n=1; Opit...    41   0.015
UniRef50_A5V539 Cluster: Transketolase, central region; n=4; Bac...    41   0.019
UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1; Rub...    40   0.025
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy...    40   0.045
UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component bet...    39   0.059
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido...    39   0.059
UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component sub...    39   0.059
UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol ox...    39   0.059
UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, be...    38   0.10 
UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1 comp...    38   0.10 
UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) b...    38   0.14 
UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifi...    38   0.14 
UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5; Bac...    38   0.14 
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac...    38   0.14 
UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16; Bacill...    38   0.14 
UniRef50_A1SN85 Cluster: Transketolase, central region; n=4; cel...    38   0.14 
UniRef50_A0GUE2 Cluster: Putative uncharacterized protein; n=1; ...    38   0.14 
UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit (L...    38   0.14 
UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) b...    38   0.18 
UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase...    38   0.18 
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet...    38   0.18 
UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subun...    37   0.24 
UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=...    37   0.24 
UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1; Novo...    37   0.31 
UniRef50_A0H598 Cluster: Transketolase, central region; n=2; Chl...    37   0.31 
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib...    36   0.41 
UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2; Bac...    36   0.41 
UniRef50_Q59820 Cluster: Pyruvate dehydrogenase (Lipoamide): sub...    36   0.55 
UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta ...    36   0.55 
UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1; ...    36   0.55 
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub...    36   0.55 
UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component sub...    36   0.55 
UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino ac...    36   0.72 
UniRef50_A5KTL2 Cluster: Transketolase, central region; n=1; can...    36   0.72 
UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component sub...    36   0.72 
UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase ...    35   1.3  
UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1; Opit...    35   1.3  
UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2; Bacter...    34   1.7  
UniRef50_A1WCY6 Cluster: MscS Mechanosensitive ion channel; n=9;...    34   1.7  
UniRef50_Q11G19 Cluster: Transketolase-like; n=2; Proteobacteria...    34   2.2  
UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component sub...    34   2.2  
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB...    33   2.9  
UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component, ...    33   2.9  
UniRef50_Q4Q589 Cluster: Putative uncharacterized protein; n=3; ...    33   2.9  
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB...    33   3.9  
UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc...    33   3.9  
UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, bet...    33   3.9  
UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase beta-su...    33   5.1  
UniRef50_A5V556 Cluster: Transketolase domain protein; n=1; Sphi...    33   5.1  
UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium ce...    33   5.1  
UniRef50_Q0V1N4 Cluster: Putative uncharacterized protein; n=2; ...    33   5.1  
UniRef50_A6R6A4 Cluster: Putative uncharacterized protein; n=1; ...    33   5.1  
UniRef50_UPI0000F2CF67 Cluster: PREDICTED: hypothetical protein;...    32   6.8  
UniRef50_Q3WCG4 Cluster: Transketolase, central region:Transketo...    32   6.8  
UniRef50_Q12AT9 Cluster: Putative uncharacterized protein precur...    32   6.8  
UniRef50_A4FQT8 Cluster: Nitric oxide synthase oxygenase; n=1; S...    32   6.8  
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox...    32   6.8  
UniRef50_Q9E938 Cluster: ICP4 protein; n=2; Gallid herpesvirus 3...    32   8.9  
UniRef50_A0K2C4 Cluster: Putative uncharacterized protein; n=1; ...    32   8.9  
UniRef50_Q9ZQ76 Cluster: Putative uncharacterized protein At2g03...    32   8.9  

>UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to
           2-oxoisovalerate dehydrogenase beta subunit,
           mitochondrial precursor (Branched-chain alpha-keto acid
           dehydrogenase E1 component beta chain) (BCKDH E1-beta);
           n=1; Macaca mulatta|Rep: PREDICTED: similar to
           2-oxoisovalerate dehydrogenase beta subunit,
           mitochondrial precursor (Branched-chain alpha-keto acid
           dehydrogenase E1 component beta chain) (BCKDH E1-beta) -
           Macaca mulatta
          Length = 340

 Score =  110 bits (265), Expect = 2e-23
 Identities = 43/61 (70%), Positives = 55/61 (90%)
 Frame = +1

Query: 256 PLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLIN 435
           PLT GF +E+++TVQEECFL+LEAPI+RV G+D PFPH+FEPFY+PDKW+CY AL ++IN
Sbjct: 280 PLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMIN 339

Query: 436 Y 438
           Y
Sbjct: 340 Y 340



 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 30/52 (57%), Positives = 42/52 (80%)
 Frame = +3

Query: 3   AAEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVT 158
           AAE+VP+E Y +PL +A+ ++ G+  TLV WGTQVHV+ EVA MA++KLGV+
Sbjct: 195 AAEQVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVS 246



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 24/33 (72%), Positives = 29/33 (87%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C+VIDL++I+PWD +TVC SV KTGR LISHEA
Sbjct: 247 CEVIDLRTIIPWDVDTVCKSVIKTGRLLISHEA 279


>UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit
           beta, mitochondrial precursor; n=84; cellular
           organisms|Rep: 2-oxoisovalerate dehydrogenase subunit
           beta, mitochondrial precursor - Homo sapiens (Human)
          Length = 392

 Score =  110 bits (265), Expect = 2e-23
 Identities = 43/61 (70%), Positives = 55/61 (90%)
 Frame = +1

Query: 256 PLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLIN 435
           PLT GF +E+++TVQEECFL+LEAPI+RV G+D PFPH+FEPFY+PDKW+CY AL ++IN
Sbjct: 332 PLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMIN 391

Query: 436 Y 438
           Y
Sbjct: 392 Y 392



 Score = 72.9 bits (171), Expect = 4e-12
 Identities = 31/52 (59%), Positives = 42/52 (80%)
 Frame = +3

Query: 3   AAEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVT 158
           AAEEVP+E Y +PL +A+ ++ G+  TLV WGTQVHV+ EVA MA++KLGV+
Sbjct: 247 AAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVS 298



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 23/33 (69%), Positives = 29/33 (87%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C+VIDL++I+PWD +T+C SV KTGR LISHEA
Sbjct: 299 CEVIDLRTIIPWDVDTICKSVIKTGRLLISHEA 331


>UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 391

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 33/61 (54%), Positives = 43/61 (70%)
 Frame = +1

Query: 256 PLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLIN 435
           P+T GFGAE+AA++ E CF  LEAP+ARV G D PFP V+E FY+P K +   A+   +N
Sbjct: 331 PITGGFGAEIAASITERCFQRLEAPVARVCGLDTPFPLVYETFYMPTKNKVLDAIKATVN 390

Query: 436 Y 438
           Y
Sbjct: 391 Y 391



 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 26/48 (54%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
 Frame = +3

Query: 3   AAEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA-DMARD 143
           A EEVP EDY LPL +A+ +R G+  TL+GWG Q+ VL E   D A+D
Sbjct: 247 AVEEVPEEDYMLPLSEAEVIRKGSDITLIGWGAQLAVLEEACEDAAKD 294



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 20/33 (60%), Positives = 29/33 (87%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C++IDL++++PWD+ETV  SV KTG+ L+SHEA
Sbjct: 298 CELIDLRTLIPWDKETVEASVSKTGKLLVSHEA 330


>UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18;
           cellular organisms|Rep: Transketolase, central region -
           Shewanella sp. (strain W3-18-1)
          Length = 325

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 29/55 (52%), Positives = 42/55 (76%)
 Frame = +1

Query: 256 PLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQAL 420
           PLT GF  E+AAT+Q+ECFL+LE+PI+RV G D P+P + E  Y+PD  + ++A+
Sbjct: 265 PLTGGFAGEIAATIQQECFLYLESPISRVCGLDTPYPLIHEKEYIPDALKTFEAI 319



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 22/33 (66%), Positives = 29/33 (87%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C+VIDL+++ PWD +TV NSVKKTGR L++HEA
Sbjct: 232 CEVIDLRTLSPWDIDTVANSVKKTGRLLVNHEA 264



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMA 137
           EVP  DY + LGKA+ +R G   TLV WG Q+ +L + ADMA
Sbjct: 184 EVPAGDYEIELGKAEVVREGKDITLVAWGAQMEILEKAADMA 225


>UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit
           beta; n=67; cellular organisms|Rep: 2-oxoisovalerate
           dehydrogenase subunit beta - Pseudomonas aeruginosa
          Length = 350

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 30/44 (68%), Positives = 32/44 (72%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLP 393
           T GFGAEL + VQE CF HLEAPI RVTGWD P+PH  E  Y P
Sbjct: 292 TCGFGAELMSLVQEHCFHHLEAPIERVTGWDTPYPHAQEWAYFP 335



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 20/32 (62%), Positives = 27/32 (84%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL+S+ P D ET+  SVKKTGRC+I+HEA
Sbjct: 258 EIIDLRSLWPLDLETIVASVKKTGRCVIAHEA 289



 Score = 37.9 bits (84), Expect = 0.14
 Identities = 19/42 (45%), Positives = 26/42 (61%)
 Frame = +3

Query: 6   AEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD 131
           A +VP   Y +PL KA  +R GAA T++ +GT V+V    AD
Sbjct: 210 ASQVPDGYYKVPLDKAAIVRPGAALTVLTYGTMVYVAQAAAD 251


>UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular
           organisms|Rep: Pyruvate dehydrogenase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 338

 Score = 65.3 bits (152), Expect = 8e-10
 Identities = 28/66 (42%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFP-HVFEPFYLPDKWRCYQAL 420
           +   P T G GAE+A T+QEE  +H EAPI R+ G+DAP P H  E +YLP   R    +
Sbjct: 273 VHEAPKTGGLGAEIATTIQEEALVHQEAPIKRIAGFDAPMPLHSLEDYYLPQAVRIQDGI 332

Query: 421 IQLINY 438
            + +++
Sbjct: 333 RETVDF 338



 Score = 40.3 bits (90), Expect = 0.025
 Identities = 18/32 (56%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ P D ET+ +S KKTGR  I HEA
Sbjct: 245 EVIDLRTLSPLDIETITDSFKKTGRAAIVHEA 276


>UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component beta
           subunit; n=16; Ascomycota|Rep: Pyruvate dehydrogenase E1
           component beta subunit - Sclerotinia sclerotiorum 1980
          Length = 403

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 30/62 (48%), Positives = 41/62 (66%), Gaps = 2/62 (3%)
 Frame = +1

Query: 259 LTSGFGAELAATVQE--ECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLI 432
           + +G GAE+AA++QE  E FL +EAP+ARV GW    P +FE F +PD  R Y A+ + I
Sbjct: 342 VNAGIGAEVAASIQEDKETFLRMEAPVARVAGWGIHMPLMFEKFNVPDVTRVYDAIKKSI 401

Query: 433 NY 438
            Y
Sbjct: 402 RY 403



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 18/32 (56%), Positives = 28/32 (87%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL+++ PWD+ETV  SV+KTGRC++ HE+
Sbjct: 309 ELIDLRTVYPWDKETVLKSVRKTGRCVVVHES 340



 Score = 41.5 bits (93), Expect = 0.011
 Identities = 18/53 (33%), Positives = 31/53 (58%)
 Frame = +3

Query: 3   AAEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVTV 161
           A E+VP++ YTLPL  A+ ++ G   TL+ +G  ++      + A   LG++V
Sbjct: 256 AVEQVPIDAYTLPLSVAEIVKPGKDLTLISYGHPMYTCSAALEAAERDLGISV 308


>UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 376

 Score = 56.4 bits (130), Expect = 4e-07
 Identities = 26/57 (45%), Positives = 33/57 (57%)
 Frame = +1

Query: 268 GFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLINY 438
           G GAE+AAT+Q   FL LEAP+ RV GW       +E   LPD  R Y A+ + + Y
Sbjct: 320 GVGAEVAATIQTGAFLRLEAPVQRVAGWSTHTGLTYEKLILPDVTRIYDAIKRTLEY 376



 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 17/32 (53%), Positives = 26/32 (81%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL++I PWD +TV +SV KTGR ++ HE+
Sbjct: 284 ELIDLRTIYPWDRQTVLDSVNKTGRAIVVHES 315


>UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1,
           transketolase beta subunit; n=8; cellular organisms|Rep:
           Pyruvate dehydrogenase complex E1, transketolase beta
           subunit - Uncultured methanogenic archaeon RC-I
          Length = 325

 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
 Frame = +1

Query: 268 GFGAELAATVQEECFLHLEAPIARVTGWDAPFP-HVFEPFYLPDKWRCYQALIQLINY 438
           GFG+E++A V EE  LHL+ P+ RV+G+D  FP +  E  YLPD  R   A  +++ Y
Sbjct: 268 GFGSEISAIVSEEAILHLKGPVIRVSGYDIRFPLYKLEDQYLPDPERVVAAAKEVMQY 325



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 20/46 (43%), Positives = 29/46 (63%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDK 146
           EEVP  +YT+P+GKA+    G   T+V WG  V+V LE A   +++
Sbjct: 182 EEVPDGEYTVPIGKAKVTLPGKDLTIVAWGAMVNVSLEAAKTLQEQ 227



 Score = 37.9 bits (84), Expect = 0.14
 Identities = 16/32 (50%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ P D++ + +SVKKTGR +I  EA
Sbjct: 232 EVIDLRTLKPLDKDAILDSVKKTGRLVIVEEA 263


>UniRef50_A0JY24 Cluster: Transketolase, central region; n=2;
           cellular organisms|Rep: Transketolase, central region -
           Arthrobacter sp. (strain FB24)
          Length = 354

 Score = 52.0 bits (119), Expect = 8e-06
 Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH-VFEPFYLPDKWRCYQAL 420
           +   P TSG GAE+A  + + CF  L+AP+ R+TG+D P+P    E  Y+P+  R    +
Sbjct: 286 VHEAPRTSGLGAEVAQLITQSCFDTLKAPVERITGFDVPYPSGDLEDEYIPNIDRILFGI 345

Query: 421 IQLINY 438
            +++ Y
Sbjct: 346 QRVLEY 351



 Score = 32.7 bits (71), Expect = 5.1
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL+ + P DE  +  SV+KT R ++ HEA
Sbjct: 258 EVLDLRWLKPIDEAALAASVRKTRRAVVVHEA 289


>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
           Proteobacteria|Rep: Transketolase domain protein -
           Marinomonas sp. MWYL1
          Length = 701

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 22/31 (70%), Positives = 27/31 (87%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL++I PWD+ETV  SV+KTGRCLI HE
Sbjct: 607 EVIDLRTIQPWDKETVLASVEKTGRCLIVHE 637



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 21/38 (55%), Positives = 27/38 (71%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVF 375
           T+GFGAE+ AT+ +E F  L+API R+T  D P PH F
Sbjct: 641 TAGFGAEIVATLADELFFSLDAPIQRLTMPDIPNPHNF 678



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 15/30 (50%), Positives = 20/30 (66%)
 Frame = +3

Query: 18  PVEDYTLPLGKAQTLRVGAAATLVGWGTQV 107
           P +DY +P GKA+T+  G A T+V WG  V
Sbjct: 563 PGDDYVIPFGKAKTILTGTALTVVCWGAMV 592


>UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=60; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Leifsonia xyli
           subsp. xyli
          Length = 337

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 25/56 (44%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
 Frame = +1

Query: 274 GAELAATVQEECFLHLEAPIARVTGWDAPFPHV-FEPFYLPDKWRCYQALIQLINY 438
           G+E+AA V E+ F  LEAP+ RV G+D PFP    E  YLPD  R  + + + + Y
Sbjct: 282 GSEVAAVVGEKAFYSLEAPVLRVAGFDTPFPPAKLESLYLPDADRILEVVDRSLAY 337



 Score = 35.1 bits (77), Expect = 0.96
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL+S+ P D   V  SV+KTGR +++ EA
Sbjct: 244 EVVDLRSLAPIDYAPVLRSVQKTGRLVVAQEA 275



 Score = 32.7 bits (71), Expect = 5.1
 Identities = 16/45 (35%), Positives = 25/45 (55%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDK 146
           EV   +  LPL  ++ +R G  AT+V W   V V L  A++A ++
Sbjct: 195 EVDTLENPLPLHASRIVRSGTDATIVAWAGMVPVALRAAEIAAEE 239


>UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta
           subunit, mitochondrial, putative; n=2; Trypanosoma
           cruzi|Rep: 2-oxoisovalerate dehydrogenase beta subunit,
           mitochondrial, putative - Trypanosoma cruzi
          Length = 368

 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 24/61 (39%), Positives = 37/61 (60%)
 Frame = +1

Query: 256 PLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQALIQLIN 435
           P TSG G+E+ + + ++CFL LEAP  RV   D P P + E  YLP++ +  +A+  +  
Sbjct: 309 PKTSGIGSEIVSCITQDCFLSLEAPPMRVCCLDTPHP-LNERLYLPNELKVCEAIKYITG 367

Query: 436 Y 438
           Y
Sbjct: 368 Y 368



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 18/32 (56%), Positives = 26/32 (81%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL+S+ PWD E V  SV+KTGR +++HEA
Sbjct: 277 ELIDLRSLKPWDREMVTQSVRKTGRVIVTHEA 308



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 18/44 (40%), Positives = 28/44 (63%)
 Frame = +3

Query: 30  YTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVTV 161
           YT+PLGK + L  G   T+V +G QV V ++ A+ A  + G++V
Sbjct: 234 YTIPLGKGKILCEGRDVTIVTYGAQVGVAMKAAERAAQE-GISV 276


>UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) beta
           subunit; n=24; Bacteria|Rep: Pyruvate dehydrogenase E1
           (Lipoamide) beta subunit - Bacillus halodurans
          Length = 328

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 20/33 (60%), Positives = 26/33 (78%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C++IDL++I P D ET+  SVKKTGR +I HEA
Sbjct: 234 CEIIDLRTIAPIDRETIIESVKKTGRAIIIHEA 266



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH-VFEPFYLPDKWRCYQALIQLINY 438
           T+G G E+ A + EE  ++L+AP+ R+ G+D P P  + E  YLP   R ++ + + +++
Sbjct: 269 TAGLGGEITALINEEALIYLKAPVKRIAGFDIPVPQFLSENQYLPTIERMFRGIEETVSF 328



 Score = 36.7 bits (81), Expect = 0.31
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLG 152
           E+VP   Y +PLG+A+ ++ G   T++ WG  V   L+ A  A    G
Sbjct: 184 EDVPNTLYEIPLGQAKVVQEGEDVTVIAWGGMVREALQAAKEAEKAHG 231


>UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent
           dehydrogenases, E1 component beta subunit; n=13;
           cellular organisms|Rep: Thiamine pyrophosphate-dependent
           dehydrogenases, E1 component beta subunit - Geobacillus
           kaustophilus
          Length = 339

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
 Frame = +1

Query: 208 VQFREENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH--VFEP 381
           +Q  ++   +L +    L+ G  AE+AA   E C   LEAP+ R+   D P P+    E 
Sbjct: 261 IQSVKKTHRLLVVDEDYLSYGMTAEIAAIAAEHCLYDLEAPVKRIAVPDVPIPYSRPLEQ 320

Query: 382 FYLPDKWRCYQALIQLIN 435
           F LP+  + ++  IQL+N
Sbjct: 321 FVLPNADKIFREAIQLVN 338



 Score = 39.9 bits (89), Expect = 0.034
 Identities = 20/38 (52%), Positives = 23/38 (60%)
 Frame = +3

Query: 15  VPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           VP E YT+PLGKA  +R G   T+VG    VH  LE A
Sbjct: 197 VPEEAYTVPLGKANIVREGTDITIVGIQMTVHQALEAA 234



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 17/31 (54%), Positives = 24/31 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+S++P D+ET+  SVKKT R L+  E
Sbjct: 245 EVIDLRSLVPLDKETIIQSVKKTHRLLVVDE 275


>UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=23; Mollicutes|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Mycoplasma
           pneumoniae
          Length = 327

 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 21/32 (65%), Positives = 27/32 (84%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL++I PWD+ETV NSVKKTGR L+  EA
Sbjct: 235 ELIDLRTISPWDKETVFNSVKKTGRLLVVTEA 266



 Score = 33.5 bits (73), Expect = 2.9
 Identities = 15/29 (51%), Positives = 19/29 (65%)
 Frame = +1

Query: 280 ELAATVQEECFLHLEAPIARVTGWDAPFP 366
           E+ A+V EE F +L+A   RVTGWD   P
Sbjct: 275 EIIASVTEELFSYLKAAPQRVTGWDIVVP 303



 Score = 31.9 bits (69), Expect = 8.9
 Identities = 12/39 (30%), Positives = 24/39 (61%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEV 125
           +E+P + YT+P+G+A  +  G   T+V +G  +  L+ +
Sbjct: 185 QEIPADYYTVPIGQANLISQGNNLTIVSYGPTMFDLINM 223


>UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit
           beta; n=12; cellular organisms|Rep: 2-oxoisovalerate
           dehydrogenase subunit beta - Thermus thermophilus
           (strain HB27 / ATCC BAA-163 / DSM 7039)
          Length = 324

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 24/68 (35%), Positives = 38/68 (55%)
 Frame = +1

Query: 235 VLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFEPFYLPDKWRCYQ 414
           V+ +   P  + F +E+AAT+ E+    L AP  RVTG+D P+P+  +  YLP   R   
Sbjct: 257 VVLVSDAPRHASFVSEVAATIAEDLLDMLLAPPIRVTGFDTPYPYAQDKLYLPTVTRILN 316

Query: 415 ALIQLINY 438
           A  + ++Y
Sbjct: 317 AAKRALDY 324



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 23/45 (51%), Positives = 30/45 (66%), Gaps = 1/45 (2%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQV-HVLLEVADMAR 140
           EEVP EDYTL +GKA   R G   TL+G+GT +  VL   A++A+
Sbjct: 182 EEVPEEDYTLSIGKAALRREGKDLTLIGYGTVMPEVLQAAAELAK 226



 Score = 41.5 bits (93), Expect = 0.011
 Identities = 16/32 (50%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL++++PWD E V NSV KTGR ++  +A
Sbjct: 232 EVLDLRTLMPWDYEAVMNSVAKTGRVVLVSDA 263


>UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, beta
           subunit; n=4; Bacilli|Rep: Acetoin dehydrogenase, E1
           component, beta subunit - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 346

 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 19/32 (59%), Positives = 27/32 (84%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+S+ PWD+ETV +SVKKTGR ++  E+
Sbjct: 246 EVIDLRSVSPWDQETVLDSVKKTGRLIVIDES 277



 Score = 37.1 bits (82), Expect = 0.24
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
 Frame = +3

Query: 15  VPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           VP E YT+ +GKA   R G   T+V  G  V V  E A+ +A D++ V V
Sbjct: 198 VPEEPYTIEIGKANVTREGDDLTIVAIGKMVAVAEETAEKLAEDQVSVEV 247


>UniRef50_A6UDY4 Cluster: Transketolase central region; n=1;
           Sinorhizobium medicae WSM419|Rep: Transketolase central
           region - Sinorhizobium medicae WSM419
          Length = 325

 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 21/39 (53%), Positives = 25/39 (64%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAP 360
           +  G +TSG  AELAA + EECF  LE P+ RV G D P
Sbjct: 260 VSEGVMTSGVAAELAARISEECFDFLEQPVLRVAGEDIP 298



 Score = 32.3 bits (70), Expect = 6.8
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           EE+ ++   LP GKA   R G    +V +  QV   LE AD +AR  +  TV
Sbjct: 182 EEIDLDADPLPWGKAAVRRQGDDLVIVTYSRQVFYALEAADALARKGIEATV 233


>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
           subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
           dehydrogenase beta subunit - Bacteroides
           thetaiotaomicron
          Length = 678

 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
 Frame = +1

Query: 265 SGFGAELAATVQEECFLHLEAPIARVTGWDAP--FPHVFEPFYLPDKWRCYQALIQLINY 438
           SGFGAELAA +  + F +L+ P+ RV     P  F  + E   LPD+ + Y+A  +L+ Y
Sbjct: 619 SGFGAELAAMIGTDMFRYLDGPVQRVGSTFTPVGFNPILEKEILPDEAKIYEAAKKLLEY 678



 Score = 39.5 bits (88), Expect = 0.045
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VID++S++P D+E +  SVKKT + L+ HE
Sbjct: 584 EVIDIRSLIPLDKEAIFESVKKTSKALVVHE 614



 Score = 35.9 bits (79), Expect = 0.55
 Identities = 18/50 (36%), Positives = 27/50 (54%)
 Frame = +3

Query: 3   AAEEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLG 152
           AA  VP ED+ +P GKA+  R G   +++ +G   H  L VA+    + G
Sbjct: 532 AAAVVP-EDFEVPFGKARIRREGTDLSIITYGNTTHFCLHVAEQLEKESG 580


>UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Transketolase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 325

 Score = 45.6 bits (103), Expect = 7e-04
 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH--VFEPFYLPDKWRCYQALIQLI 432
           T GF  E+ A V EE    L+AP  RVTG D P P     E FY+PD+    +A+  ++
Sbjct: 267 TGGFAGEICALVAEEALGSLKAPFRRVTGPDIPVPFSPPLEAFYIPDEHDLVKAVESIV 325



 Score = 39.9 bits (89), Expect = 0.034
 Identities = 15/32 (46%), Positives = 26/32 (81%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ P D++ + +SV+KTGR ++ HEA
Sbjct: 233 EVIDLRTLAPLDKDAILDSVRKTGRLVVLHEA 264



 Score = 35.5 bits (78), Expect = 0.72
 Identities = 15/44 (34%), Positives = 24/44 (54%)
 Frame = +3

Query: 15  VPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDK 146
           VP E+Y +P+GKA   R G+  T+V W   +   ++ A +   K
Sbjct: 185 VPEEEYLVPIGKADVKRQGSDVTIVTWSKMLGAAMKGAALLEQK 228


>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
           Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
           dehydrogenase alpha and beta fusion); n=7;
           Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
           Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
           oxoisovalerate dehydrogenase alpha and beta fusion) -
           Chlamydia pneumoniae (Chlamydophila pneumoniae)
          Length = 678

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
 Frame = +1

Query: 268 GFGAELAATVQEECFLHLEAPIARVTGWDAPFPH--VFEPFYLPDKWRCYQALIQLINY 438
           GFG+EL AT+ E+ + +L+API R+ G  AP P+  V E   LP K    QA   L  +
Sbjct: 620 GFGSELVATMSEQGYAYLDAPIRRLGGLHAPVPYSKVLENEVLPHKESILQAAKSLAEF 678



 Score = 39.1 bits (87), Expect = 0.059
 Identities = 17/32 (53%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL++++P D  TV  S++KTGR L+ HEA
Sbjct: 584 EVIDLRTMVPCDFATVLKSLEKTGRLLVIHEA 615



 Score = 35.5 bits (78), Expect = 0.72
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = +3

Query: 27  DYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           DY LP GKA  +  G   T+V WG  + + LEVA
Sbjct: 540 DYVLPFGKAAIVHPGKDLTIVSWGMPLVLSLEVA 573


>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
           Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
           sp. (strain CCS1)
          Length = 675

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
 Frame = +1

Query: 217 REENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH--VFEPFYL 390
           R+ N AV+ +   P   GFG E+AA + E  F  L+AP+AR+   + P P+    E  Y+
Sbjct: 600 RKTNRAVV-VHEAPRFGGFGGEIAAAITEAAFDWLDAPVARIGAPEMPVPYNDRLERQYM 658

Query: 391 PDKWRCYQAL 420
           PD  R  +A+
Sbjct: 659 PDARRIAEAV 668



 Score = 36.7 bits (81), Expect = 0.31
 Identities = 15/32 (46%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VID ++I P+D +T+  SV+KT R ++ HEA
Sbjct: 580 EVIDPRTIKPFDIDTIVGSVRKTNRAVVVHEA 611


>UniRef50_A5UU14 Cluster: Transketolase, central region; n=3;
           Chloroflexi (class)|Rep: Transketolase, central region -
           Roseiflexus sp. RS-1
          Length = 322

 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 23/51 (45%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           EVP E YT+PLGKA+  R G   T+V +   VH+  + AD +ARD + V +
Sbjct: 180 EVPEESYTVPLGKARLAREGRDMTVVTYSRMVHLSQQAADILARDGIEVEI 230



 Score = 34.3 bits (75), Expect = 1.7
 Identities = 20/52 (38%), Positives = 31/52 (59%)
 Frame = +1

Query: 214 FREENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           F++ N AV+ +     + G  AE+AA + E  F +L+APIARV   + P P+
Sbjct: 248 FKKTNRAVV-VTEDWQSFGTSAEIAARLYEYGFDYLDAPIARVNFREVPMPY 298


>UniRef50_A0CTB9 Cluster: Chromosome undetermined scaffold_27, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_27,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 149

 Score = 44.8 bits (101), Expect = 0.001
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
 Frame = +1

Query: 190 LGRGDRVQFREENWAVLDIPRGPLTSGFGAELAATVQEE-CFLHLEAPIARVTGWDAPFP 366
           L R   +Q  ++   V+ +  G   SG GAE+AA + E   F +L+API RVTG + P P
Sbjct: 30  LDRETILQSVKKTGRVVCVEEGWPQSGIGAEIAALIMEGGAFKYLDAPIQRVTGVEVPTP 89

Query: 367 HVF--EPFYLPDKWRCYQALIQLINY*KLYTII*VKF 471
           + F  E    P   +   A++ +I    L  I  +K+
Sbjct: 90  YAFNLEAISFPKTEQIVDAVLNVIKRGSLIYIQIIKW 126



 Score = 39.5 bits (88), Expect = 0.045
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           C+VI+L+S+ P D ET+  SVKKTGR +   E
Sbjct: 19  CEVINLRSLRPLDRETILQSVKKTGRVVCVEE 50


>UniRef50_A5V352 Cluster: Transketolase, central region; n=1;
           Sphingomonas wittichii RW1|Rep: Transketolase, central
           region - Sphingomonas wittichii RW1
          Length = 334

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL++I PWD +TV  SV +TGR +I HEA
Sbjct: 241 ELIDLRTIAPWDRDTVLASVARTGRAMIVHEA 272


>UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=3;
           Bacteria|Rep: Pyruvate dehydrogenase beta-subunit -
           consortium cosmid clone pGZ1
          Length = 333

 Score = 44.0 bits (99), Expect = 0.002
 Identities = 17/32 (53%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL++I PWD + V  S ++TGR L++HEA
Sbjct: 234 EVIDLRTIWPWDRDCVVRSAQRTGRVLVAHEA 265


>UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, beta
           subunit; n=7; Bacteria|Rep: Dehydrogenase complex, E1
           component, beta subunit - Geobacter sulfurreducens
          Length = 328

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           ++G G  LAA + EECF  L AP+ RV+G D P P+
Sbjct: 266 SAGLGGHLAAIIAEECFDRLLAPVRRVSGLDVPMPY 301



 Score = 37.1 bits (82), Expect = 0.24
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           C+V+DL+++ P D  T   SVKKTGR ++  E
Sbjct: 231 CEVVDLRTLTPLDTATFTASVKKTGRAVVVEE 262


>UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;
           n=24; cellular organisms|Rep: Pyruvate dehydrogenase E1
           beta subunit - Rhodopseudomonas palustris
          Length = 469

 Score = 43.6 bits (98), Expect = 0.003
 Identities = 19/42 (45%), Positives = 27/42 (64%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           I  G   +G GAEL+A + E  F +L+AP+ RV+G D P P+
Sbjct: 403 IEEGWQQNGVGAELSARIMEHAFDYLDAPVTRVSGKDVPMPY 444



 Score = 40.7 bits (91), Expect = 0.019
 Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
 Frame = +3

Query: 12  EVP-VEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           EVP ++DY +P+GKA+ +R G   TL+ W   +   L+ AD +A+D +   V
Sbjct: 325 EVPKLDDYVIPIGKARIVREGKDVTLISWSHGMTYALKAADELAKDGIAAEV 376



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 15/31 (48%), Positives = 22/31 (70%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+++ P D +T+  SVKKTGR +   E
Sbjct: 375 EVIDLRTLRPLDTDTIIASVKKTGRAVTIEE 405


>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
           usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
           Solibacter usitatus (strain Ellin6076)
          Length = 397

 Score = 43.2 bits (97), Expect = 0.004
 Identities = 18/36 (50%), Positives = 25/36 (69%)
 Frame = +1

Query: 259 LTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           LT GFGAE+AA + E CF +L+AP+ R+   D+  P
Sbjct: 336 LTMGFGAEVAARIAENCFEYLDAPVRRIAAADSFVP 371



 Score = 39.9 bits (89), Expect = 0.034
 Identities = 16/31 (51%), Positives = 24/31 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+SI P DE+ +  SV+KT R +++HE
Sbjct: 303 EVIDLRSISPLDEDLISRSVRKTNRVIVAHE 333



 Score = 37.9 bits (84), Expect = 0.14
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = +3

Query: 18  PVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           P  D+ +P GK +  R G   T+V WG  VH+  E A
Sbjct: 256 PDSDFVIPFGKGRIARAGTDLTIVAWGYTVHLAQEAA 292


>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
           component subunits alpha and beta; n=18;
           Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
           component subunits alpha and beta - Gramella forsetii
           (strain KT0803)
          Length = 685

 Score = 43.2 bits (97), Expect = 0.004
 Identities = 18/41 (43%), Positives = 27/41 (65%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD 131
           +EVPV+ YTLP GKA  LR G   +++ +G  VH  ++V +
Sbjct: 544 QEVPVDYYTLPFGKASLLREGEEISIISYGAGVHWAIDVLE 584



 Score = 43.2 bits (97), Expect = 0.004
 Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
 Frame = +1

Query: 271 FGAELAATVQEECFLHLEAPIARVTGWDAPFPHV--FEPFYLPDKWRCYQALIQLINY 438
           F +E+AA + E CF  L+AP+ RV   D P P     E  YLP + R  + L  LI Y
Sbjct: 629 FASEVAAQISESCFESLDAPVIRVGSMDTPIPFAKNLEKQYLPQE-RFKEKLKNLIEY 685



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 17/31 (54%), Positives = 24/31 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           D+IDL+S+ P D E++C SV KTG+C+I  E
Sbjct: 592 DLIDLRSLQPLDMESICKSVTKTGKCIILTE 622


>UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=41; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Bacillus
           subtilis
          Length = 325

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           +EVP E+YT+ LGKA   R G   +++ +G  VH  L+ AD + +D +   V
Sbjct: 182 QEVPEEEYTIELGKADVKREGTDLSIITYGAMVHESLKAADELEKDGISAEV 233



 Score = 35.9 bits (79), Expect = 0.55
 Identities = 14/32 (43%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL+++ P D +T+  SV+KTGR ++  EA
Sbjct: 232 EVVDLRTVSPLDIDTIIASVEKTGRAIVVQEA 263


>UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=4; Bacteria|Rep: Pyruvate dehydrogenase
           E1 component subunit beta - Acholeplasma laidlawii
          Length = 327

 Score = 42.3 bits (95), Expect = 0.006
 Identities = 18/32 (56%), Positives = 26/32 (81%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL++I P DEET+ NSVKKTG+ ++  EA
Sbjct: 232 EIIDLRTISPIDEETILNSVKKTGKFMVVTEA 263



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 15/33 (45%), Positives = 23/33 (69%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQV 107
           +EVP E Y +P+GKA+ ++ G   T+V WG+ V
Sbjct: 182 QEVPAEMYEIPIGKAKVVKQGTDMTVVAWGSIV 214



 Score = 33.1 bits (72), Expect = 3.9
 Identities = 16/33 (48%), Positives = 18/33 (54%)
 Frame = +1

Query: 268 GFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           G  AEL   V E+ F HLEA   R TG+D   P
Sbjct: 268 GPAAELITMVNEKAFFHLEAAPVRFTGFDITVP 300


>UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit
           beta; n=39; Bacteria|Rep: 2-oxoisovalerate dehydrogenase
           subunit beta - Bacillus subtilis
          Length = 327

 Score = 41.9 bits (94), Expect = 0.008
 Identities = 18/40 (45%), Positives = 25/40 (62%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD 131
           EVP +DY LP+GKA   R G   T++ +G  VH  L+ A+
Sbjct: 183 EVPADDYVLPIGKADVKREGDDITVITYGLCVHFALQAAE 222



 Score = 33.1 bits (72), Expect = 3.9
 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
 Frame = +1

Query: 277 AELAATVQEECFLHLEAPIARVTGWD---APFPHVFEPFYL--PDK 399
           +E+AA + E C   L+API R+ G D    P+    E +++  PDK
Sbjct: 271 SEVAAIISEHCLFDLDAPIKRLAGPDIPAMPYAPTMEKYFMVNPDK 316


>UniRef50_Q479Q1 Cluster: Transketolase, central
           region:Transketolase, C-terminal precursor; n=2;
           Rhodocyclaceae|Rep: Transketolase, central
           region:Transketolase, C-terminal precursor -
           Dechloromonas aromatica (strain RCB)
          Length = 337

 Score = 41.5 bits (93), Expect = 0.011
 Identities = 18/36 (50%), Positives = 24/36 (66%)
 Frame = +1

Query: 268 GFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVF 375
           G GAE+AA + E+ F  L+AP+ R+ G DAP P  F
Sbjct: 261 GVGAEIAALIAEQAFASLKAPVVRLGGPDAPVPSSF 296



 Score = 37.1 bits (82), Expect = 0.24
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+S+ P DE  +  + +KTGR ++ HEA
Sbjct: 225 EVIDLRSLKPLDEAAILATARKTGRVVVVHEA 256



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           EVP E   +PLG+A T+R G   +L+ +G  VH   + A
Sbjct: 176 EVPSEAVPIPLGQATTVRAGTDVSLISYGKTVHHCAQAA 214


>UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
           complex, E1 component, beta subunit; n=1; Nitratiruptor
           sp. SB155-2|Rep: Pyruvate/2-oxoglutarate dehydrogenase
           complex, E1 component, beta subunit - Nitratiruptor sp.
           (strain SB155-2)
          Length = 325

 Score = 41.5 bits (93), Expect = 0.011
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           T G+GAE+ A + EE F  L+AP  R+ G D P P+
Sbjct: 262 TGGYGAEVIARITEELFYELDAPPLRIAGEDVPVPY 297



 Score = 33.1 bits (72), Expect = 3.9
 Identities = 15/31 (48%), Positives = 21/31 (67%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL S+ P D +T+  SVKKT R ++  E
Sbjct: 228 EVIDLNSLRPLDMKTISESVKKTKRVVLVEE 258


>UniRef50_A7CXF2 Cluster: Transketolase central region; n=1;
           Opitutaceae bacterium TAV2|Rep: Transketolase central
           region - Opitutaceae bacterium TAV2
          Length = 398

 Score = 41.1 bits (92), Expect = 0.015
 Identities = 23/51 (45%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
 Frame = +1

Query: 253 GPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHV--FEPFYLPDK 399
           G  T GFGAEL A + EE F  LEAP  R+   D P P     E  Y P +
Sbjct: 335 GHRTHGFGAELVARLTEEHFFDLEAPPLRIASADIPVPFAPELEAAYRPTR 385


>UniRef50_A5V539 Cluster: Transketolase, central region; n=4;
           Bacteria|Rep: Transketolase, central region -
           Sphingomonas wittichii RW1
          Length = 324

 Score = 40.7 bits (91), Expect = 0.019
 Identities = 17/32 (53%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ PWDE  V  S+ KT R +I+HEA
Sbjct: 231 EVIDLRTVQPWDEAAVLASLAKTHRLVIAHEA 262


>UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep: Transketolase,
           central region - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 330

 Score = 40.3 bits (90), Expect = 0.025
 Identities = 18/32 (56%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VID + I P+D ETV  SV+KTGR +++HEA
Sbjct: 232 EVIDPRGIRPFDFETVLRSVEKTGRVVLAHEA 263



 Score = 37.9 bits (84), Expect = 0.14
 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           EVP  ++ +PLG+A   R G   TLV W   V   LE AD +A + + V V
Sbjct: 183 EVPEGEHLVPLGEAVVRRQGGDVTLVAWSAMVLKALEAADRLAEEGIEVEV 233



 Score = 37.9 bits (84), Expect = 0.14
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
 Frame = +1

Query: 220 EENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHV--FEPFYLP 393
           E+   V+     PL  G G+E+AA + E     LEAP+ RV   D P P     E F +P
Sbjct: 252 EKTGRVVLAHEAPLPGGPGSEVAAVIAERAIASLEAPVRRVGAPDVPVPQSAHLERFVVP 311


>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
           dehydrogenase; n=1; Photorhabdus luminescens subsp.
           laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
           dehydrogenase - Photorhabdus luminescens subsp.
           laumondii
          Length = 665

 Score = 39.5 bits (88), Expect = 0.045
 Identities = 13/31 (41%), Positives = 25/31 (80%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VI+L+S++PWD++ +  S++KTGR ++  E
Sbjct: 570 EVIELRSLVPWDKQRIAESLRKTGRLIVVQE 600


>UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component beta
           subunit; n=6; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component beta subunit - Synechococcus
           elongatus (Thermosynechococcus elongatus)
          Length = 327

 Score = 39.1 bits (87), Expect = 0.059
 Identities = 16/36 (44%), Positives = 24/36 (66%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           T G GAEL+A++ E  F  L+AP+ R++  D P P+
Sbjct: 265 TGGIGAELSASIMERYFDELDAPVIRLSSKDVPTPY 300



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 14/38 (36%), Positives = 24/38 (63%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLE 122
           E++P E+Y LPL KA+ +R G   T++ +    H +L+
Sbjct: 181 EDLPEEEYLLPLDKAEVVRTGEDVTILTYSRMRHHVLQ 218


>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
           Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
           component - Acidobacteria bacterium (strain Ellin345)
          Length = 736

 Score = 39.1 bits (87), Expect = 0.059
 Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
 Frame = +1

Query: 259 LTSGFGAELAATVQEECFLHLEAPIARVTGWD--APFPHVFEPFYLPDKWRCYQALIQLI 432
           L+ G+GAE+AA + +E F  L+AP+ RV   D    +    E   LP     + A++++ 
Sbjct: 675 LSWGYGAEIAARIADELFDELDAPVKRVAAKDTFVAYQPALEDVILPQSDDLFAAMLEMS 734

Query: 433 NY 438
            Y
Sbjct: 735 KY 736



 Score = 35.1 bits (77), Expect = 0.96
 Identities = 12/31 (38%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           ++IDL+++ P+D E +  S+ KT R +++HE
Sbjct: 642 ELIDLRTLNPYDFEAIAESIHKTNRVIVAHE 672



 Score = 33.5 bits (73), Expect = 2.9
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +3

Query: 18  PVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVTV 161
           P  DY +P GKA+ ++ G   T+V +G  V   L+ A     + GV+V
Sbjct: 594 PGPDYMVPFGKAKIVKAGHDITVVTYGAVVPRALQAAQKIERENGVSV 641


>UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=35; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Rickettsia
           felis (Rickettsia azadi)
          Length = 326

 Score = 39.1 bits (87), Expect = 0.059
 Identities = 17/32 (53%), Positives = 23/32 (71%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           C+VIDL++I P D +T+  SVKKT R +I  E
Sbjct: 229 CEVIDLRTIKPLDTDTIIESVKKTNRLVIVEE 260



 Score = 38.7 bits (86), Expect = 0.078
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHV--FEPFYLPDKWRCYQA 417
           +  G   +G GA +A+ V +E F +L+API  V+G D P P     E   LP +    +A
Sbjct: 258 VEEGWFFAGVGASIASIVMKEAFDYLDAPIEIVSGKDVPLPFAVNLEKLALPSESDVIEA 317

Query: 418 LIQLINY 438
           + ++  Y
Sbjct: 318 VKKVCYY 324



 Score = 31.9 bits (69), Expect = 8.9
 Identities = 14/44 (31%), Positives = 28/44 (63%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARD 143
           +VP     +P G+A+ LR G++ T+V +  QV + L+ A++ ++
Sbjct: 181 DVPETIEPIPFGQAKILREGSSVTIVTFSIQVKLALDAANVLQN 224


>UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol
           oxidoreductase subunit beta; n=65; Bacteria|Rep:
           Acetoin:2,6-dichlorophenolindophenol oxidoreductase
           subunit beta - Bacillus subtilis
          Length = 342

 Score = 39.1 bits (87), Expect = 0.059
 Identities = 20/39 (51%), Positives = 23/39 (58%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           EVP + YT+PLGKA   R G   TL   G QV+  LE A
Sbjct: 195 EVPEDYYTIPLGKADIKREGNDVTLFAVGKQVNTALEAA 233


>UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, beta
           subunit; n=1; Psychroflexus torquis ATCC 700755|Rep:
           Pyruvate dehydrogenase E1 component, beta subunit -
           Psychroflexus torquis ATCC 700755
          Length = 325

 Score = 38.3 bits (85), Expect = 0.10
 Identities = 15/33 (45%), Positives = 23/33 (69%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C++ID++++ P D E +  SVKKT R +I  EA
Sbjct: 230 CEIIDIRTVRPLDYEAILKSVKKTNRLIILEEA 262



 Score = 35.1 bits (77), Expect = 0.96
 Identities = 16/40 (40%), Positives = 23/40 (57%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD 131
           EVP E+YT+PLG A   R G   T+V +G  +    + A+
Sbjct: 182 EVPEEEYTIPLGVADIKREGTDVTIVSFGKIIKEAYKAAE 221


>UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1
           component, alpha and beta subunit; n=1; Plesiocystis
           pacifica SIR-1|Rep: 2-oxoisovalerate dehydrogenase, E1
           component, alpha and beta subunit - Plesiocystis
           pacifica SIR-1
          Length = 757

 Score = 38.3 bits (85), Expect = 0.10
 Identities = 16/31 (51%), Positives = 25/31 (80%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           ++ID+++I+P D +TV  SV+KTGR L+ HE
Sbjct: 627 EMIDMRTIVPPDMDTVMASVRKTGRLLVVHE 657


>UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
           chain; n=25; Bacteria|Rep: Acetoin dehydrogenase
           (TPP-dependent) beta chain - Rhizobium loti
           (Mesorhizobium loti)
          Length = 332

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 16/32 (50%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL++I P D++TV +SVKKT R +  +EA
Sbjct: 235 EVVDLRTIRPMDKQTVIDSVKKTSRLMCVYEA 266



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 17/37 (45%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
 Frame = +1

Query: 262 TSGFGAELAATVQE-ECFLHLEAPIARVTGWDAPFPH 369
           T G GAE++A + E E F +L+API R+ G + P P+
Sbjct: 269 TLGIGAEVSAMIAESEAFDYLDAPIVRLGGAETPIPY 305


>UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifica
           SIR-1|Rep: Transketolase - Plesiocystis pacifica SIR-1
          Length = 336

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = +1

Query: 253 GPLTSGFGAELAATVQEECFLHLEAPIARVTG 348
           GP   G GAELAA   +   LHL+AP+ R+ G
Sbjct: 274 GPRRHGLGAELAALFADRSILHLDAPVLRICG 305


>UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5;
           Bacteria|Rep: Transketolase, central region -
           Roseiflexus sp. RS-1
          Length = 327

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 3/76 (3%)
 Frame = +1

Query: 220 EENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWD---APFPHVFEPFYL 390
           E+    L +    LT G G E+AA + E  F +L+AP+ R+   D    PF    E  ++
Sbjct: 252 EKTGRALIVHEDVLTGGIGGEIAAIIAEHAFEYLDAPVRRLASPDLFATPFADPLEDHFM 311

Query: 391 PDKWRCYQALIQLINY 438
            +  +   A+  L  Y
Sbjct: 312 LNPQKIAAAMRDLARY 327



 Score = 37.1 bits (82), Expect = 0.24
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+++ P D   +  SV+KTGR LI HE
Sbjct: 232 EVIDLRTLAPLDRAAILASVEKTGRALIVHE 262


>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
           Bacteria|Rep: Transketolase, central region -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 823

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 15/33 (45%), Positives = 25/33 (75%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           C++ID +S++P++ E V  SVKKTG+ L+  +A
Sbjct: 706 CEIIDARSLVPFNYEKVIESVKKTGKILLVSDA 738


>UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16;
           Bacilli|Rep: E1 component beta subunit - Lactobacillus
           reuteri
          Length = 325

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 2/60 (3%)
 Frame = +1

Query: 265 SGFGAELAATVQEECFLHLEAPIARVTGWDA--PFPHVFEPFYLPDKWRCYQALIQLINY 438
           +G GA++A+ + E   ++L+AP+ RV   ++  PFP   E  +LP       A+ ++INY
Sbjct: 267 AGVGAQVASAISEGAIMYLDAPVTRVAAPNSVYPFPQA-ENVWLPGARDIEDAVREVINY 325



 Score = 35.9 bits (79), Expect = 0.55
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           ++IDL+S+ P D +T+  S+KKT R +I  EA
Sbjct: 232 EIIDLRSLYPLDTDTIFESIKKTHRVVIVQEA 263



 Score = 35.1 bits (77), Expect = 0.96
 Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 12  EVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA-DMARDKLGVTV 161
           EVP + YT+PL KA  ++ G   T++ +G +V    + A  +A+D +   +
Sbjct: 183 EVPDDKYTVPLDKANVVQEGTDVTIIAYGGEVSEAQKAAKKLAKDNISAEI 233


>UniRef50_A1SN85 Cluster: Transketolase, central region; n=4;
           cellular organisms|Rep: Transketolase, central region -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 347

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           + VP  DY  P+GKA  +R G+  T+V     VH  L+VA+ +A D + V V
Sbjct: 203 DAVPDGDYETPIGKANVVRSGSDVTVVTISLSVHHALDVAERLADDGIDVEV 254



 Score = 34.3 bits (75), Expect = 1.7
 Identities = 14/31 (45%), Positives = 22/31 (70%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +V+DL+S++P D E +  SV KTGR ++  E
Sbjct: 253 EVLDLRSLVPLDREAILASVAKTGRLVVVDE 283


>UniRef50_A0GUE2 Cluster: Putative uncharacterized protein; n=1;
           Burkholderia phytofirmans PsJN|Rep: Putative
           uncharacterized protein - Burkholderia phytofirmans PsJN
          Length = 383

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
 Frame = -2

Query: 341 TRAIGASKCRKHSSCTVAASSAPNPDVSGPRGISSTAQFSSRNCTRSPRPRAGSTADR*R 162
           +R    S+C   S C   A+ +  P     R + S  QFS+R   R  RPR  + A R  
Sbjct: 62  SRNAAQSQCTAQSQC---AAQSRRPRRESIRRVRSCRQFSARLAARRRRPRWAALARRIH 118

Query: 161 HSDAELVP-RHVCYLQQH 111
           H D    P RH+    QH
Sbjct: 119 HGDVTPSPRRHLSVAFQH 136


>UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit
           (Lipoamide); n=1; Sulfolobus solfataricus|Rep: Pyruvate
           dehydrogenase, beta subunit (Lipoamide) - Sulfolobus
           solfataricus
          Length = 332

 Score = 37.9 bits (84), Expect = 0.14
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VID+++ +P DEET+  S +KTGR LI  E
Sbjct: 239 EVIDVRTFVPLDEETIIKSARKTGRVLIVDE 269



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 19/50 (38%), Positives = 28/50 (56%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVT 158
           EEVP E Y +  GKA   + G   T++  G  VH  L+ A+M + K G++
Sbjct: 189 EEVPEEPYEIEFGKAAIRKEGTDLTIISAGLMVHRSLKAAEMLQ-KEGIS 237


>UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
           chain; n=2; Rhodobacterales|Rep: Acetoin dehydrogenase
           (TPP-dependent) beta chain - Rhodobacterales bacterium
           HTCC2654
          Length = 333

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 16/41 (39%), Positives = 24/41 (58%)
 Frame = +1

Query: 244 IPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           I  G  + G  AE+A+ + E+ F HL+AP+ R+   D P P
Sbjct: 261 IDEGHQSYGVTAEIASRLNEKAFYHLDAPVLRMGAMDVPVP 301



 Score = 35.5 bits (78), Expect = 0.72
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VID ++I+P DE+T+ +SVKKT R ++  E
Sbjct: 233 EVIDPRTIVPLDEKTLLDSVKKTSRAIVIDE 263



 Score = 33.1 bits (72), Expect = 3.9
 Identities = 15/40 (37%), Positives = 22/40 (55%)
 Frame = +3

Query: 15  VPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADM 134
           VP E+Y +P G+A   R G   TL+   + V V  + A+M
Sbjct: 185 VPEEEYLIPFGEANVKREGKDITLIATSSMVQVAEKAAEM 224


>UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
           Alpha and Beta Fusion; n=6; cellular organisms|Rep:
           (Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta
           Fusion - Dokdonia donghaensis MED134
          Length = 693

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +V+DL+++ P D ETV  SVKK G+CL+  E
Sbjct: 598 EVVDLRTLHPLDYETVFKSVKKCGKCLVITE 628



 Score = 36.7 bits (81), Expect = 0.31
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
 Frame = +1

Query: 238 LDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWD---APFPHVFEPFYLPDKWRC 408
           L I   P  +GF   L  ++QEECF +L+AP+  +   +    P   V E   +P   + 
Sbjct: 624 LVITEEPSNNGFSRGLQGSIQEECFQYLDAPVMLIGSENMPAIPLNSVLEQTMIPSTEKV 683

Query: 409 YQALIQLINY 438
            + + +LI Y
Sbjct: 684 KKKIQELIAY 693


>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
           n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
           component beta - Ostreococcus tauri
          Length = 835

 Score = 37.5 bits (83), Expect = 0.18
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPHVFE 378
           T G GA L+A V E  F  L+AP+ R+   DAP P+  E
Sbjct: 773 TGGVGATLSAIVSENLFDELDAPVMRLCMEDAPVPYASE 811


>UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subunit;
           n=9; Proteobacteria|Rep: Dehydrogenase, E1 component,
           beta subunit - Coxiella burnetii
          Length = 353

 Score = 37.1 bits (82), Expect = 0.24
 Identities = 15/29 (51%), Positives = 23/29 (79%)
 Frame = +2

Query: 158 CDVIDLQSILPWDEETVCNSVKKTGRCLI 244
           C++IDL++I P D ET+  S++KTGR L+
Sbjct: 231 CELIDLRTIKPLDWETIYVSIRKTGRLLV 259


>UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=2;
           Plasmodium falciparum|Rep: Pyruvate dehydrogenase beta
           subunit - Plasmodium falciparum
          Length = 415

 Score = 37.1 bits (82), Expect = 0.24
 Identities = 17/32 (53%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL S+ P+D ET+  S+KKT +CLI  E+
Sbjct: 319 EVIDLISLKPFDMETIEKSLKKTKKCLILDES 350



 Score = 34.7 bits (76), Expect = 1.3
 Identities = 14/40 (35%), Positives = 25/40 (62%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA 128
           +E+P+  YTLP+ KA+ ++ G   T++ +G   H+  E A
Sbjct: 269 QEIPLLPYTLPIDKAEVVKNGKDLTVLSYGITRHLASEAA 308


>UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1;
           Novosphingobium aromaticivorans DSM 12444|Rep:
           Transketolase domain protein - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 327

 Score = 36.7 bits (81), Expect = 0.31
 Identities = 16/33 (48%), Positives = 22/33 (66%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAP 360
           T+G GAE+AA +QE  F  L+AP+ R+   D P
Sbjct: 267 TAGPGAEIAAQIQERAFFDLDAPVLRLGARDFP 299



 Score = 36.3 bits (80), Expect = 0.41
 Identities = 16/32 (50%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+S++P D E V  SV +T R ++ HEA
Sbjct: 233 EVIDLRSLVPLDWEHVLESVSRTHRAMVVHEA 264


>UniRef50_A0H598 Cluster: Transketolase, central region; n=2;
           Chloroflexus|Rep: Transketolase, central region -
           Chloroflexus aggregans DSM 9485
          Length = 343

 Score = 36.7 bits (81), Expect = 0.31
 Identities = 15/32 (46%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+DL+++ P DE  +  +V+KTG+ LI HEA
Sbjct: 249 EVLDLRTLKPLDEAAILATVQKTGKVLIVHEA 280


>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
           Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
           component - Solibacter usitatus (strain Ellin6076)
          Length = 697

 Score = 36.3 bits (80), Expect = 0.41
 Identities = 18/45 (40%), Positives = 27/45 (60%)
 Frame = +1

Query: 220 EENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWD 354
           E+   VL +    L+ G+GAE+AA + +E F  L+AP+ RV   D
Sbjct: 623 EKTSRVLVVHEDTLSWGYGAEIAARIADELFDKLDAPVRRVGALD 667



 Score = 33.5 bits (73), Expect = 2.9
 Identities = 12/31 (38%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +++DL+++ P+D + +  SV+KT R L+ HE
Sbjct: 603 EILDLRTLAPYDWDAIRASVEKTSRVLVVHE 633


>UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2;
           Bacteria|Rep: Transketolase, central region - Comamonas
           testosteroni KF-1
          Length = 334

 Score = 36.3 bits (80), Expect = 0.41
 Identities = 18/44 (40%), Positives = 25/44 (56%)
 Frame = +1

Query: 235 VLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           +L +    LT GFGAE+AA +  E F  L+ P+AR+   D   P
Sbjct: 266 LLIVHEANLTGGFGAEIAARIHAESFGALKKPVARLATPDIRIP 309



 Score = 33.9 bits (74), Expect = 2.2
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VI+ + I P+D  T+  SV KTGR LI HEA
Sbjct: 241 EVINARWIAPFDWPTLQQSVHKTGRLLIVHEA 272


>UniRef50_Q59820 Cluster: Pyruvate dehydrogenase (Lipoamide):
           subunit E1beta; n=1; Staphylococcus aureus|Rep: Pyruvate
           dehydrogenase (Lipoamide): subunit E1beta -
           Staphylococcus aureus
          Length = 154

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 15/32 (46%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ P D +T+  SV+KTGR ++  EA
Sbjct: 61  EVIDLRTVQPIDVDTIVASVEKTGRAVVVQEA 92


>UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta
           subunit; n=3; Proteobacteria|Rep: Pyruvate dehydrogenase
           complex E1 beta subunit - Thiobacillus ferrooxidans
           (Acidithiobacillus ferrooxidans)
          Length = 343

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 21/65 (32%), Positives = 31/65 (47%)
 Frame = +1

Query: 175 AVDPALGRGDRVQFREENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWD 354
           A+ P    G     R+ + AV+ +       G G+E+ A + EECF  L+A   RV   D
Sbjct: 238 ALKPMDRAGIAASVRKTHRAVV-VEEDEAPVGVGSEVMAILNEECFFDLDAAPVRVHALD 296

Query: 355 APFPH 369
            P P+
Sbjct: 297 VPIPY 301


>UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 360

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 17/31 (54%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VID++S+ P+D  T+ NSVKKT R LI  E
Sbjct: 267 EVIDIRSLKPFDLYTIGNSVKKTHRVLIVEE 297



 Score = 32.3 bits (70), Expect = 6.8
 Identities = 14/36 (38%), Positives = 20/36 (55%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           T G GA L A + E    +L+API  ++  D P P+
Sbjct: 301 TGGIGASLTAAITENFIDYLDAPIVCLSSQDVPTPY 336


>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
           E1 component subunit beta - Zymomonas mobilis
          Length = 462

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 21/61 (34%), Positives = 32/61 (52%)
 Frame = +1

Query: 187 ALGRGDRVQFREENWAVLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           +L + +R+   E+ W V  I          +E+AA   EE F +L+AP+ RVT  D P P
Sbjct: 385 SLAKTNRIVTVEDGWPVCSI---------SSEIAAIAMEEGFDNLDAPVLRVTNADTPTP 435

Query: 367 H 369
           +
Sbjct: 436 Y 436



 Score = 32.7 bits (71), Expect = 5.1
 Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
 Frame = +3

Query: 12  EVP-VEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD-MARDKLGVTV 161
           +VP ++D+ LP+GKA+ +R G   T+V +   V   L  A+ +A++ +   V
Sbjct: 317 DVPKMDDFVLPIGKARIIREGKDVTIVSYSIGVSFALTAAEALAKEGIDAEV 368


>UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=33; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Staphylococcus
           aureus
          Length = 325

 Score = 35.9 bits (79), Expect = 0.55
 Identities = 15/32 (46%), Positives = 24/32 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VIDL+++ P D +T+  SV+KTGR ++  EA
Sbjct: 232 EVIDLRTVQPIDVDTIVASVEKTGRAVVVQEA 263



 Score = 35.5 bits (78), Expect = 0.72
 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVA-DMARDKLGVTV 161
           EEVP E+YT+ +GKA   + G   +++ +G  V   ++ A ++ +D   V V
Sbjct: 182 EEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEV 233


>UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino acid
            adenylation; n=3; Pseudomonas syringae group|Rep:
            Non-ribosomal peptide synthase:Amino acid adenylation -
            Pseudomonas syringae pv. syringae (strain B728a)
          Length = 2666

 Score = 35.5 bits (78), Expect = 0.72
 Identities = 18/38 (47%), Positives = 22/38 (57%)
 Frame = +3

Query: 315  ALGGADSSSDRLGRALPACLRTFLLTGQVALLPSLDTT 428
            A GGAD S D L   L ACL  +++  Q+ LL SL  T
Sbjct: 1011 AAGGADLSIDSLREQLTACLPDYMVPAQIMLLDSLPLT 1048


>UniRef50_A5KTL2 Cluster: Transketolase, central region; n=1;
           candidate division TM7 genomosp. GTL1|Rep:
           Transketolase, central region - candidate division TM7
           genomosp. GTL1
          Length = 333

 Score = 35.5 bits (78), Expect = 0.72
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+ + +I P DEET+  S+KKTGR + + EA
Sbjct: 233 EVMHVPTIKPLDEETILESLKKTGRAVTAEEA 264


>UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta, mitochondrial precursor; n=144; cellular
           organisms|Rep: Pyruvate dehydrogenase E1 component
           subunit beta, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 359

 Score = 35.5 bits (78), Expect = 0.72
 Identities = 17/35 (48%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
 Frame = +1

Query: 268 GFGAELAATVQE-ECFLHLEAPIARVTGWDAPFPH 369
           G GAE+ A + E   F  L+AP  RVTG D P P+
Sbjct: 300 GVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPY 334


>UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase E1
           beta subunit; n=5; Deltaproteobacteria|Rep:
           Branched-chain keto acid dehydrogenase E1 beta subunit -
           Myxococcus xanthus
          Length = 352

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 16/31 (51%), Positives = 23/31 (74%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+S+ P+D E +  SV+KTGR L  +E
Sbjct: 255 EVIDLRSLWPYDWELIKASVQKTGRVLFVNE 285


>UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1;
           Opitutaceae bacterium TAV2|Rep: Transketolase central
           region - Opitutaceae bacterium TAV2
          Length = 327

 Score = 34.7 bits (76), Expect = 1.3
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +++DL++I P D +TV  SVKKT R LI  E
Sbjct: 233 EIVDLRTIRPLDFDTVLASVKKTNRVLIVEE 263


>UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2;
           Bacteria|Rep: Transketolase-like protein - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 330

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 12/32 (37%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+D ++++P D++T+ +SV+KTGR ++   A
Sbjct: 232 EVVDPRTLVPMDKKTILDSVRKTGRLVVCDNA 263


>UniRef50_A1WCY6 Cluster: MscS Mechanosensitive ion channel; n=9;
           Proteobacteria|Rep: MscS Mechanosensitive ion channel -
           Acidovorax sp. (strain JS42)
          Length = 376

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 20/58 (34%), Positives = 28/58 (48%)
 Frame = +3

Query: 21  VEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMARDKLGVTVTSSICSRSCPG 194
           VE Y    G A T ++ A+ATL+ WG +  V   V       LGV +T+ + S    G
Sbjct: 121 VERYRRHHGAAGTGQISASATLMSWGLRTLVWATVLLAILSNLGVNITAFVASLGVGG 178


>UniRef50_Q11G19 Cluster: Transketolase-like; n=2;
           Proteobacteria|Rep: Transketolase-like - Mesorhizobium
           sp. (strain BNC1)
          Length = 323

 Score = 33.9 bits (74), Expect = 2.2
 Identities = 17/41 (41%), Positives = 24/41 (58%)
 Frame = +3

Query: 9   EEVPVEDYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVAD 131
           EEVP E Y +PL KA     G+  T+VG G  +  +L+ A+
Sbjct: 183 EEVPDEQYEVPLDKAIVRMEGSDLTIVGSGASMPEVLKAAE 223


>UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component
           subunit beta; n=66; cellular organisms|Rep: Pyruvate
           dehydrogenase E1 component subunit beta - Zygnema
           circumcarinatum (Green alga)
          Length = 325

 Score = 33.9 bits (74), Expect = 2.2
 Identities = 15/36 (41%), Positives = 21/36 (58%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHLEAPIARVTGWDAPFPH 369
           T G GA L A + E  F +L+API  ++  D P P+
Sbjct: 265 TGGIGATLRAAIMEHFFDYLDAPILCLSSQDVPTPY 300


>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
           SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
           DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
          Length = 725

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 14/37 (37%), Positives = 23/37 (62%)
 Frame = +3

Query: 27  DYTLPLGKAQTLRVGAAATLVGWGTQVHVLLEVADMA 137
           DY +PLGKA+ +R G+A T++     V   ++ A+ A
Sbjct: 587 DYCIPLGKAKIVRPGSACTVLATSVMVQASIKAAEEA 623


>UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component,
           beta subunit; n=24; Streptococcus|Rep: Pyruvate
           dehydrogenase (E1) component, beta subunit -
           Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)
          Length = 337

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 12/32 (37%), Positives = 25/32 (78%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +V+D ++++P D+E +  SVKKTG+ ++ ++A
Sbjct: 240 EVVDPRTLVPLDKELIFESVKKTGKLMLVNDA 271


>UniRef50_Q4Q589 Cluster: Putative uncharacterized protein; n=3;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 1222

 Score = 33.5 bits (73), Expect = 2.9
 Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
 Frame = +3

Query: 39   PLGKAQTLRVGAAATLVGW------GTQVHVLLEVADMARDKLGVTVTSSICSRS 185
            PLG +   R GA   +VGW      G  V    +VA   RDK+  TVT   CSRS
Sbjct: 1169 PLGLSN--RAGAFVDVVGWRVLRVDGNAVRTGRDVAAQVRDKIEFTVTLQPCSRS 1221


>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
           SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
           DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
          Length = 729

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 17/41 (41%), Positives = 24/41 (58%)
 Frame = +1

Query: 235 VLDIPRGPLTSGFGAELAATVQEECFLHLEAPIARVTGWDA 357
           VL + +G   + +G  LA  +Q  CF  L+ PIARV G +A
Sbjct: 653 VLIVEQGASGTSYGGWLADELQRRCFDWLDQPIARVHGAEA 693


>UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1;
           Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
           dehydrogenase - Prochlorococcus marinus (strain MIT
           9312)
          Length = 329

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 13/28 (46%), Positives = 20/28 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLI 244
           ++ID++ I P+  E + NSVKKTGR  +
Sbjct: 232 EIIDMRIINPFHSELITNSVKKTGRLFV 259


>UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, beta
           subunit; n=1; marine gamma proteobacterium HTCC2080|Rep:
           Acetoin dehydrogenase E1 component, beta subunit -
           marine gamma proteobacterium HTCC2080
          Length = 325

 Score = 33.1 bits (72), Expect = 3.9
 Identities = 14/32 (43%), Positives = 23/32 (71%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHEA 256
           +VID +++ P DEE++  SV KTGR ++  E+
Sbjct: 231 EVIDPRTLSPLDEESILASVSKTGRLVVVDES 262


>UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase
           beta-subunit; n=1; Streptomyces rochei|Rep: Probable
           pyruvate dehydrogenase beta-subunit - Streptomyces
           rochei (Streptomyces parvullus)
          Length = 344

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 12/29 (41%), Positives = 21/29 (72%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLIS 247
           +V+D++SI P D+  +C SV KTG  +++
Sbjct: 231 EVVDVRSIRPLDDALICASVAKTGHLVVA 259


>UniRef50_A5V556 Cluster: Transketolase domain protein; n=1;
           Sphingomonas wittichii RW1|Rep: Transketolase domain
           protein - Sphingomonas wittichii RW1
          Length = 330

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 12/27 (44%), Positives = 21/27 (77%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCL 241
           +V+D +S++P D+E +  SV+KTGR +
Sbjct: 230 EVVDPRSLVPLDKELILRSVRKTGRAI 256


>UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Transketolase-like - Clostridium
           cellulolyticum H10
          Length = 346

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 13/29 (44%), Positives = 22/29 (75%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLIS 247
           +VIDL++I P DE+ +  S+ KTGR +++
Sbjct: 253 EVIDLRTIKPIDEDIIFESLAKTGRLIVT 281


>UniRef50_Q0V1N4 Cluster: Putative uncharacterized protein; n=2;
           cellular organisms|Rep: Putative uncharacterized protein
           - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 324

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
 Frame = -2

Query: 314 RKHSSCTVAASSAPNPDVSGPRGIS--STAQFSSRNCTRSPRPRAGSTADR*RHSDAELV 141
           R  S   V  S +P+P  +G R  +  S ++   R+ TRSP PR GS A R      E +
Sbjct: 35  RPGSRSPVRNSRSPSPRRNGRRSYTPDSRSRSRGRSYTRSPTPRDGSPAPRSAKIVVEAL 94

Query: 140 PRHV 129
            R+V
Sbjct: 95  TRNV 98


>UniRef50_A6R6A4 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 1011

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 16/55 (29%), Positives = 27/55 (49%)
 Frame = -2

Query: 332 IGASKCRKHSSCTVAASSAPNPDVSGPRGISSTAQFSSRNCTRSPRPRAGSTADR 168
           + +++ +++      A  A     SGP GI S A+    + ++ P PR GS  DR
Sbjct: 353 LASAQIKRYQHAYALARGADETHPSGPLGIWSRAEEDWNSMSQHPHPRRGSDRDR 407


>UniRef50_UPI0000F2CF67 Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 253

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 16/36 (44%), Positives = 20/36 (55%)
 Frame = -2

Query: 287 ASSAPNPDVSGPRGISSTAQFSSRNCTRSPRPRAGS 180
           A++AP   V GPR + S A   SR  TR P P  G+
Sbjct: 121 AAAAPKKKVPGPRELPSPALAPSRTPTRPPAPSPGT 156


>UniRef50_Q3WCG4 Cluster: Transketolase, central
           region:Transketolase, C terminal; n=7; Bacteria|Rep:
           Transketolase, central region:Transketolase, C terminal
           - Frankia sp. EAN1pec
          Length = 351

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 17/34 (50%), Positives = 21/34 (61%)
 Frame = +1

Query: 265 SGFGAELAATVQEECFLHLEAPIARVTGWDAPFP 366
           +G GAE+AA +Q E F  LEAP+ RV     P P
Sbjct: 283 AGPGAEIAAILQRELFGVLEAPVERVGARFVPNP 316


>UniRef50_Q12AT9 Cluster: Putative uncharacterized protein
           precursor; n=1; Polaromonas sp. JS666|Rep: Putative
           uncharacterized protein precursor - Polaromonas sp.
           (strain JS666 / ATCC BAA-500)
          Length = 566

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 22/69 (31%), Positives = 30/69 (43%)
 Frame = -2

Query: 347 PVTRAIGASKCRKHSSCTVAASSAPNPDVSGPRGISSTAQFSSRNCTRSPRPRAGSTADR 168
           P T A GAS C +    +   S+      S   G  S +  +S  CT +P P AG +  +
Sbjct: 379 PATLASGASICYRGKYTSNTLSTLDTVTASASTGSGSVSGTASATCTATP-PNAGLSVTK 437

Query: 167 *RHSDAELV 141
               D ELV
Sbjct: 438 ICDVDLELV 446


>UniRef50_A4FQT8 Cluster: Nitric oxide synthase oxygenase; n=1;
           Saccharopolyspora erythraea NRRL 2338|Rep: Nitric oxide
           synthase oxygenase - Saccharopolyspora erythraea (strain
           NRRL 23338)
          Length = 380

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
 Frame = +1

Query: 190 LGRGDRVQFREENWAVLDIP-RGPLTSGF-GAELAATVQEECFLHLEAPIARVTGWDAPF 363
           L  G RV  R+  W    +P R  L     G   A TV +ECF HL   +A   G   P 
Sbjct: 70  LAYGARVALRDSGWCTSGVPWRRLLVRDLRGLRNATTVAKECFEHLR--LATNAGRIQPL 127

Query: 364 PHVFEP 381
             VF P
Sbjct: 128 ISVFAP 133


>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
           decarboxylase; n=1; Streptomyces virginiae|Rep:
           Branched-chain alpha-keto acid decarboxylase -
           Streptomyces virginiae
          Length = 677

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 14/31 (45%), Positives = 21/31 (67%)
 Frame = +2

Query: 161 DVIDLQSILPWDEETVCNSVKKTGRCLISHE 253
           +VIDL+ + P D E V  SV++TGR ++  E
Sbjct: 582 EVIDLRWLTPVDREAVAASVRRTGRLVVVQE 612


>UniRef50_Q9E938 Cluster: ICP4 protein; n=2; Gallid herpesvirus 3|Rep:
            ICP4 protein - Gallid herpesvirus 3 (Marek's disease
            virus type 2)
          Length = 2033

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
 Frame = -2

Query: 317  CRKHSSCTVAASSAPNPDVSGPRGIS-STAQFSSRNCTRSPRPRAGS 180
            CR  SS + +ASS+ +   S P     S+A  SSR  +RSP   AG+
Sbjct: 946  CRSRSSSSSSASSSSSSSSSAPSSSEQSSAAPSSRTSSRSPTREAGA 992


>UniRef50_A0K2C4 Cluster: Putative uncharacterized protein; n=1;
           Arthrobacter sp. FB24|Rep: Putative uncharacterized
           protein - Arthrobacter sp. (strain FB24)
          Length = 153

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
 Frame = +1

Query: 262 TSGFGAELAATVQEECFLHL-EAPIARVTGWDAPFPHVFEPFYLPDK 399
           TSG G E+      EC+ HL  A + R+       P +F   YLPD+
Sbjct: 3   TSGPGPEITELTVRECWRHLRSASVGRLAVISHAAPEIFPVNYLPDE 49


>UniRef50_Q9ZQ76 Cluster: Putative uncharacterized protein
           At2g03400; n=1; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein At2g03400 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 131

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 17/55 (30%), Positives = 27/55 (49%)
 Frame = -1

Query: 324 LQVQKTFLLHGGGELGAEPRRERASWDIKHRPVFFTELHTVSSSQGRIDCRSMTS 160
           L+V+  +   GGGE G +P  ER+    +   +FF +L   +  Q +  CR   S
Sbjct: 64  LRVEARWPFQGGGEQGLDPSSERSESANEDILIFFFQLDLATRVQVKTKCRVFIS 118


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 465,304,214
Number of Sequences: 1657284
Number of extensions: 8941158
Number of successful extensions: 32219
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 30845
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32201
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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