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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbVm0360
         (739 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X05344-1|CAA28955.1|  412|Homo sapiens cathepsin D protein.           120   4e-27
M63138-1|AAA51922.1|  412|Homo sapiens cathepsin D protein.           120   4e-27
M11233-1|AAB59529.1|  412|Homo sapiens CTSD protein.                  120   4e-27
CR456947-1|CAG33228.1|  412|Homo sapiens CTSD protein.                120   4e-27
BT020155-1|AAV38957.1|  412|Homo sapiens cathepsin D (lysosomal ...   120   4e-27
BT006910-1|AAP35556.1|  412|Homo sapiens cathepsin D (lysosomal ...   120   4e-27
BC016320-1|AAH16320.1|  412|Homo sapiens cathepsin D protein.         120   4e-27
BC017842-1|AAH17842.1|  420|Homo sapiens napsin A aspartic pepti...   114   4e-25
AF200345-1|AAF17081.1|  420|Homo sapiens aspartyl protease 4 pro...   114   4e-25
AF098484-1|AAD13215.1|  420|Homo sapiens napsin 1 precursor prot...   114   4e-25
AF090386-1|AAD04917.1|  420|Homo sapiens napsin A protein.            114   4e-25
BC111705-1|AAI11706.1|  464|Homo sapiens NAPSB protein protein.       107   3e-23
AF200344-1|AAF17080.1|  450|Homo sapiens aspartyl protease 3 pro...   107   3e-23
M26901-1|AAA60364.1|  403|Homo sapiens renin protein.                 101   3e-21
M10152-1|AAD03461.1|  406|Homo sapiens renin protein.                 101   3e-21
L00073-1|AAA60363.1|  406|Homo sapiens renin protein.                 101   3e-21
CR536498-1|CAG38737.1|  406|Homo sapiens REN protein.                 101   3e-21
BC047752-1|AAH47752.1|  406|Homo sapiens renin protein.               101   3e-21
BC033474-1|AAH33474.1|  406|Homo sapiens renin protein.               101   3e-21
AY436324-1|AAR03502.1|  403|Homo sapiens renin protein.               101   3e-21
AL592146-1|CAI16594.1|  406|Homo sapiens renin protein.               101   3e-21
AL592114-1|CAH71224.1|  406|Homo sapiens renin protein.               101   3e-21
M84424-1|AAA52300.1|  396|Homo sapiens cathepsin E protein.            96   1e-19
J05036-1|AAA52130.1|  396|Homo sapiens CTSE protein.                   96   1e-19
BX571818-5|CAH73265.1|  363|Homo sapiens cathepsin E protein.          96   1e-19
BX571818-4|CAH73264.1|  396|Homo sapiens cathepsin E protein.          96   1e-19
BC042537-1|AAH42537.1|  396|Homo sapiens cathepsin E protein.          96   1e-19
AJ250717-1|CAB82850.1|  396|Homo sapiens procathepsin E protein.       96   1e-19
AJ250716-1|CAB82849.1|  363|Homo sapiens cathepsin E, alternativ...    96   1e-19
U75272-1|AAB18273.1|  388|Homo sapiens gastricsin protein.             90   7e-18
M23077-1|AAA60063.1|  388|Homo sapiens pepsinogen C protein.           90   7e-18
M18667-1|AAA60062.1|  385|Homo sapiens pepsinogen protein.             90   7e-18
J04443-1|AAA60074.1|  388|Homo sapiens pepsinogen protein.             90   7e-18
BC073740-1|AAH73740.1|  388|Homo sapiens progastricsin (pepsinog...    90   7e-18
AL365205-1|CAI13181.1|  388|Homo sapiens progastricsin (pepsinog...    90   7e-18
J00287-1|AAA98529.1|  388|Homo sapiens PEP protein.                    88   3e-17
BC029055-1|AAH29055.1|  388|Homo sapiens pepsinogen 5, group I (...    88   3e-17
M26032-1|AAA60061.1|  388|Homo sapiens pepsinogen A protein.           87   6e-17
X00063-1|CAA24937.1|  300|Homo sapiens protein ( Human kidney mR...    55   2e-07
BC042578-1|AAH42578.1|  104|Homo sapiens PGC protein protein.          53   1e-06
AL365205-2|CAI95135.1|  140|Homo sapiens progastricsin (pepsinog...    44   8e-04
BC014453-1|AAH14453.1|  518|Homo sapiens beta-site APP-cleaving ...    42   0.002
AY358927-1|AAQ89286.1|  518|Homo sapiens BACE2 protein.                42   0.002
AF212252-1|AAG41783.1|  439|Homo sapiens CDA13 protein.                42   0.002
AF204944-1|AAF26368.1|  518|Homo sapiens transmembrane aspartic ...    42   0.002
AF200342-1|AAF17078.1|  518|Homo sapiens aspartyl protease 1 pro...    42   0.002
AF200192-1|AAF13714.1|  518|Homo sapiens memapsin 1 protein.           42   0.002
AF188277-1|AAF35836.1|  396|Homo sapiens aspartyl protease protein.    42   0.002
AF188276-1|AAF35835.1|  468|Homo sapiens aspartyl protease protein.    42   0.002
AF178532-1|AAF29494.1|  518|Homo sapiens aspartyl protease protein.    42   0.002
AF117892-1|AAD45240.1|  518|Homo sapiens aspartic-like protease ...    42   0.002
AF050171-1|AAD45963.1|  518|Homo sapiens aspartyl protease protein.    42   0.002
AK075539-1|BAC11682.1|  423|Homo sapiens protein ( Homo sapiens ...    40   0.012
DQ007053-1|AAY16982.1|  501|Homo sapiens beta-site APP-cleaving ...    37   0.087
BC065492-1|AAH65492.1|  501|Homo sapiens beta-site APP-cleaving ...    37   0.087
AF338817-1|AAK38375.1|  457|Homo sapiens beta-site APP cleaving ...    37   0.087
AF338816-1|AAK38374.1|  476|Homo sapiens beta-site APP cleaving ...    37   0.087
AF204943-1|AAF26367.1|  501|Homo sapiens transmembrane aspartic ...    37   0.087
AF201468-1|AAF18982.1|  501|Homo sapiens APP beta-secretase prot...    37   0.087
AF200343-1|AAF17079.1|  501|Homo sapiens aspartyl protease 2 pro...    37   0.087
AF200193-1|AAF13715.1|  488|Homo sapiens memapsin 2 protein.           37   0.087
AF190725-1|AAF04142.1|  501|Homo sapiens beta-site APP cleaving ...    37   0.087
AB089958-1|BAC81826.1|  127|Homo sapiens beta-site APP cleaving ...    37   0.087
AB050438-1|BAB40933.1|  432|Homo sapiens beta-site APP cleaving ...    37   0.087
AB050437-1|BAB40932.1|  457|Homo sapiens beta-site APP cleaving ...    37   0.087
AB050436-1|BAB40931.1|  476|Homo sapiens beta-site APP cleaving ...    37   0.087
AB032975-1|BAA86463.2|  532|Homo sapiens KIAA1149 protein protein.     37   0.087
BC036084-1|AAH36084.1|  501|Homo sapiens beta-site APP-cleaving ...    35   0.35 
BC038117-1|AAH38117.1|  317|Homo sapiens LAPTM4B protein protein.      33   0.81 
BC110345-1|AAI10346.1|  327|Homo sapiens FAM129B protein protein.      33   1.1  
AY261384-1|AAO84265.1|  370|Homo sapiens lysosome-associated tra...    33   1.1  
AY219177-1|AAO64359.1|  124|Homo sapiens lysosome-associated pro...    33   1.1  
AY219176-1|AAO64358.1|  124|Homo sapiens lysosome-associated pro...    33   1.1  
AY198226-1|AAO63563.1|  124|Homo sapiens LAPTM4B protein.              33   1.1  
AY057051-1|AAL17908.2|  317|Homo sapiens lysosomal associated tr...    33   1.1  
AL445222-2|CAH72915.1|  733|Homo sapiens family with sequence si...    33   1.1  
AL445222-1|CAH72914.1|  746|Homo sapiens family with sequence si...    33   1.1  
AL390116-2|CAH73085.1|  733|Homo sapiens family with sequence si...    33   1.1  
AL390116-1|CAH73084.1|  746|Homo sapiens family with sequence si...    33   1.1  
AK025804-1|BAB15240.1|  201|Homo sapiens protein ( Homo sapiens ...    33   1.1  
AK023580-1|BAB14615.1|  396|Homo sapiens protein ( Homo sapiens ...    33   1.1  
AF527412-1|AAP14034.1|  317|Homo sapiens lysosomal associated tr...    33   1.1  
AF192911-1|AAQ13825.1|  746|Homo sapiens OC58 protein.                 33   1.1  
AF151783-1|AAK57556.1|  733|Homo sapiens MEG3 protein.                 33   1.1  
AB210016-1|BAE06098.1|  739|Homo sapiens C9orf88 variant protein...    33   1.1  
AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular...    33   1.4  
AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding ...    33   1.4  
BC001979-1|AAH01979.2|  456|Homo sapiens FAM129B protein protein.      32   1.9  
BC030606-1|AAH30606.2|  514|Homo sapiens coiled-coil domain cont...    31   5.7  
AL365205-3|CAM16152.1|   86|Homo sapiens progastricsin (pepsinog...    31   5.7  
U31468-1|AAC03241.1|  347|Homo sapiens homeobox protein protein.       30   7.5  
BC112259-1|AAI12260.1|  591|Homo sapiens MAGEL2 protein protein.       30   7.5  
BC112257-1|AAI12258.1|  591|Homo sapiens MAGEL2 protein protein.       30   7.5  
BC063834-1|AAH63834.1|  677|Homo sapiens MAGEL2 protein protein.       30   7.5  
BC035839-1|AAH35839.1|  657|Homo sapiens MAGEL2 protein protein.       30   7.5  
AJ243531-1|CAB62393.1|  529|Homo sapiens nM15 protein protein.         30   7.5  
AF200625-1|AAG28577.1|  529|Homo sapiens necdin-like protein 1 p...    30   7.5  

>X05344-1|CAA28955.1|  412|Homo sapiens cathepsin D protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>M63138-1|AAA51922.1|  412|Homo sapiens cathepsin D protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>M11233-1|AAB59529.1|  412|Homo sapiens CTSD protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>CR456947-1|CAG33228.1|  412|Homo sapiens CTSD protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>BT020155-1|AAV38957.1|  412|Homo sapiens cathepsin D (lysosomal
           aspartyl protease) protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>BT006910-1|AAP35556.1|  412|Homo sapiens cathepsin D (lysosomal
           aspartyl protease) protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>BC016320-1|AAH16320.1|  412|Homo sapiens cathepsin D protein.
          Length = 412

 Score =  120 bits (290), Expect = 4e-27
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 267 GPSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYD 446
           GP PE L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS  C   +IAC +H+KY+
Sbjct: 65  GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYN 124

Query: 447 SRKSKTYVANGTQFAIQY 500
           S KS TYV NGT F I Y
Sbjct: 125 SDKSSTYVKNGTSFDIHY 142



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 35/66 (53%), Positives = 45/66 (68%), Gaps = 11/66 (16%)
 Frame = +2

Query: 509 SLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFST 655
           SLSG+LS D V+V           GG+KV RQ F EA  +PG+ F+AAKFDGILGMA+  
Sbjct: 146 SLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPR 205

Query: 656 IAVDHV 673
           I+V++V
Sbjct: 206 ISVNNV 211



 Score = 31.5 bits (68), Expect = 3.3
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +1

Query: 139 LALIASSVMALYRVPLHRMKTARTHFHEVGTELE 240
           L L+A+   AL R+PLH+  + R    EVG  +E
Sbjct: 11  LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVE 44



 Score = 30.3 bits (65), Expect = 7.5
 Identities = 14/22 (63%), Positives = 18/22 (81%), Gaps = 1/22 (4%)
 Frame = +1

Query: 676 PVFDNMVAQGLV-QPVFSFYLN 738
           PVFDN++ Q LV Q +FSFYL+
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLS 234


>BC017842-1|AAH17842.1|  420|Homo sapiens napsin A aspartic
           peptidase protein.
          Length = 420

 Score =  114 bits (274), Expect = 4e-25
 Identities = 45/73 (61%), Positives = 60/73 (82%)
 Frame = +3

Query: 282 PLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSK 461
           PLSNY D QY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S 
Sbjct: 69  PLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASS 128

Query: 462 TYVANGTQFAIQY 500
           ++ ANGT+FAIQY
Sbjct: 129 SFQANGTKFAIQY 141



 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 25/54 (46%), Positives = 34/54 (62%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ EP L F  A FDGILG+ F  ++V+ V
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGV 199


>AF200345-1|AAF17081.1|  420|Homo sapiens aspartyl protease 4
           protein.
          Length = 420

 Score =  114 bits (274), Expect = 4e-25
 Identities = 45/73 (61%), Positives = 60/73 (82%)
 Frame = +3

Query: 282 PLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSK 461
           PLSNY D QY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S 
Sbjct: 69  PLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASS 128

Query: 462 TYVANGTQFAIQY 500
           ++ ANGT+FAIQY
Sbjct: 129 SFQANGTKFAIQY 141



 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 25/54 (46%), Positives = 34/54 (62%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ EP L F  A FDGILG+ F  ++V+ V
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGV 199


>AF098484-1|AAD13215.1|  420|Homo sapiens napsin 1 precursor
           protein.
          Length = 420

 Score =  114 bits (274), Expect = 4e-25
 Identities = 45/73 (61%), Positives = 60/73 (82%)
 Frame = +3

Query: 282 PLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSK 461
           PLSNY D QY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S 
Sbjct: 69  PLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASS 128

Query: 462 TYVANGTQFAIQY 500
           ++ ANGT+FAIQY
Sbjct: 129 SFQANGTKFAIQY 141



 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 25/54 (46%), Positives = 34/54 (62%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ EP L F  A FDGILG+ F  ++V+ V
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGV 199


>AF090386-1|AAD04917.1|  420|Homo sapiens napsin A protein.
          Length = 420

 Score =  114 bits (274), Expect = 4e-25
 Identities = 45/73 (61%), Positives = 60/73 (82%)
 Frame = +3

Query: 282 PLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSK 461
           PLSNY D QY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S 
Sbjct: 69  PLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASS 128

Query: 462 TYVANGTQFAIQY 500
           ++ ANGT+FAIQY
Sbjct: 129 SFQANGTKFAIQY 141



 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 25/54 (46%), Positives = 34/54 (62%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ EP L F  A FDGILG+ F  ++V+ V
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGV 199


>BC111705-1|AAI11706.1|  464|Homo sapiens NAPSB protein protein.
          Length = 464

 Score =  107 bits (258), Expect = 3e-23
 Identities = 42/77 (54%), Positives = 60/77 (77%)
 Frame = +3

Query: 270 PSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
           P+  PLS +LDAQY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C  H++++ 
Sbjct: 61  PASVPLSKFLDAQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNP 120

Query: 450 RKSKTYVANGTQFAIQY 500
             S ++  +GT+FAIQY
Sbjct: 121 NASSSFKPSGTKFAIQY 137



 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ E  L F  ++ DGILG+ F  ++V+ V
Sbjct: 142 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGV 195


>AF200344-1|AAF17080.1|  450|Homo sapiens aspartyl protease 3
           protein.
          Length = 450

 Score =  107 bits (258), Expect = 3e-23
 Identities = 42/77 (54%), Positives = 60/77 (77%)
 Frame = +3

Query: 270 PSPEPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDS 449
           P+  PLS +LDAQY+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C  H++++ 
Sbjct: 65  PASVPLSKFLDAQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNP 124

Query: 450 RKSKTYVANGTQFAIQY 500
             S ++  +GT+FAIQY
Sbjct: 125 NASSSFKPSGTKFAIQY 141



 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%)
 Frame = +2

Query: 512 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHV 673
           + G LS D +T+GG+K     F EA+ E  L F  ++ DGILG+ F  ++V+ V
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGV 199


>M26901-1|AAA60364.1|  403|Homo sapiens renin protein.
          Length = 403

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAQFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>M10152-1|AAD03461.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>L00073-1|AAA60363.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>CR536498-1|CAG38737.1|  406|Homo sapiens REN protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>BC047752-1|AAH47752.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>BC033474-1|AAH33474.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>AY436324-1|AAR03502.1|  403|Homo sapiens renin protein.
          Length = 403

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>AL592146-1|CAI16594.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>AL592114-1|CAH71224.1|  406|Homo sapiens renin protein.
          Length = 406

 Score =  101 bits (242), Expect = 3e-21
 Identities = 42/72 (58%), Positives = 53/72 (73%)
 Frame = +3

Query: 285 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 464
           L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC     AC+ H  +D+  S +
Sbjct: 78  LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137

Query: 465 YVANGTQFAIQY 500
           Y  NGT+  ++Y
Sbjct: 138 YKHNGTELTLRY 149



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 153 TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 207



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 204 GRVTPIFDNIISQGVLKEDVFSFYYN 229


>M84424-1|AAA52300.1|  396|Homo sapiens cathepsin E protein.
          Length = 396

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>J05036-1|AAA52130.1|  396|Homo sapiens CTSE protein.
          Length = 396

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>BX571818-5|CAH73265.1|  363|Homo sapiens cathepsin E protein.
          Length = 363

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>BX571818-4|CAH73264.1|  396|Homo sapiens cathepsin E protein.
          Length = 396

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>BC042537-1|AAH42537.1|  396|Homo sapiens cathepsin E protein.
          Length = 396

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>AJ250717-1|CAB82850.1|  396|Homo sapiens procathepsin E protein.
          Length = 396

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>AJ250716-1|CAB82849.1|  363|Homo sapiens cathepsin E, alternative
           protein.
          Length = 363

 Score = 96.3 bits (229), Expect = 1e-19
 Identities = 43/74 (58%), Positives = 54/74 (72%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS  C  T+ AC  H+++   +S
Sbjct: 68  EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125

Query: 459 KTYVANGTQFAIQY 500
            TY   G  F+IQY
Sbjct: 126 STYSQPGQSFSIQY 139



 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 30/56 (53%), Positives = 39/56 (69%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SLSG +  D V+V GL V  Q F E+V+EPG  FV A+FDGILG+ + ++AV  VT
Sbjct: 143 SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 15/26 (57%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQGLVQ-PVFSFYLN 738
           G   PVFDNM+AQ LV  P+FS Y++
Sbjct: 195 GGVTPVFDNMMAQNLVDLPMFSVYMS 220


>U75272-1|AAB18273.1|  388|Homo sapiens gastricsin protein.
          Length = 388

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 120

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 121 STYSTNGQTFSLQY 134



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 138 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193


>M23077-1|AAA60063.1|  388|Homo sapiens pepsinogen C protein.
          Length = 388

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 120

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 121 STYSTNGQTFSLQY 134



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 138 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193


>M18667-1|AAA60062.1|  385|Homo sapiens pepsinogen protein.
          Length = 385

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 61  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 117

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 118 STYSTNGQTFSLQY 131



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 135 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 190


>J04443-1|AAA60074.1|  388|Homo sapiens pepsinogen protein.
          Length = 388

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 120

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 121 STYSTNGQTFSLQY 134



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 138 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193


>BC073740-1|AAH73740.1|  388|Homo sapiens progastricsin (pepsinogen
           C) protein.
          Length = 388

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 120

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 121 STYSTNGQTFSLQY 134



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 138 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193


>AL365205-1|CAI13181.1|  388|Homo sapiens progastricsin (pepsinogen
           C) protein.
          Length = 388

 Score = 90.2 bits (214), Expect = 7e-18
 Identities = 41/74 (55%), Positives = 55/74 (74%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSSNLWVPS  C   + AC  H++++  +S
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSES 120

Query: 459 KTYVANGTQFAIQY 500
            TY  NG  F++QY
Sbjct: 121 STYSTNGQTFSLQY 134



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 25/56 (44%), Positives = 37/56 (66%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           SL+GF   D +TV  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 138 SLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193


>J00287-1|AAA98529.1|  388|Homo sapiens PEP protein.
          Length = 388

 Score = 88.2 bits (209), Expect = 3e-17
 Identities = 39/74 (52%), Positives = 50/74 (67%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           +PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS  C  +++AC  HN+++   S
Sbjct: 66  QPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDS 123

Query: 459 KTYVANGTQFAIQY 500
            TY +     +I Y
Sbjct: 124 STYQSTSETVSITY 137



 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 24/63 (38%), Positives = 33/63 (52%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTRCST 688
           S++G L  D V VGG+    Q F  + +EPG     A FDGILG+A+ +I+    T    
Sbjct: 141 SMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFD 200

Query: 689 TWW 697
             W
Sbjct: 201 NIW 203


>BC029055-1|AAH29055.1|  388|Homo sapiens pepsinogen 5, group I
           (pepsinogen A) protein.
          Length = 388

 Score = 88.2 bits (209), Expect = 3e-17
 Identities = 39/74 (52%), Positives = 50/74 (67%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           +PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS  C  +++AC  HN+++   S
Sbjct: 66  QPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDS 123

Query: 459 KTYVANGTQFAIQY 500
            TY +     +I Y
Sbjct: 124 STYQSTSETVSITY 137



 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 24/63 (38%), Positives = 33/63 (52%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTRCST 688
           S++G L  D V VGG+    Q F  + +EPG     A FDGILG+A+ +I+    T    
Sbjct: 141 SMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFD 200

Query: 689 TWW 697
             W
Sbjct: 201 NIW 203


>M26032-1|AAA60061.1|  388|Homo sapiens pepsinogen A protein.
          Length = 388

 Score = 87.0 bits (206), Expect = 6e-17
 Identities = 38/74 (51%), Positives = 50/74 (67%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 458
           +PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS  C  +++AC  HN+++   S
Sbjct: 66  QPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDS 123

Query: 459 KTYVANGTQFAIQY 500
            TY +     +I Y
Sbjct: 124 STYQSTSETVSITY 137



 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 24/63 (38%), Positives = 33/63 (52%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTRCST 688
           S++G L  D V VGG+    Q F  + +EPG     A FDGILG+A+ +I+    T    
Sbjct: 141 SMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFD 200

Query: 689 TWW 697
             W
Sbjct: 201 NIW 203


>X00063-1|CAA24937.1|  300|Homo sapiens protein ( Human kidney mRNA
           fragment for renin (aa 105-401). ).
          Length = 300

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)
 Frame = +2

Query: 509 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           ++SGFLS D +TVGG+ V  Q F E    P L F+ A+FDG++GM F   A+  VT
Sbjct: 46  TVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVT 100



 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 18/42 (42%), Positives = 26/42 (61%)
 Frame = +3

Query: 375 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQY 500
           SN+WVPS KC     AC+ H  +D+  S +Y  NGT+  ++Y
Sbjct: 1   SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRY 42



 Score = 32.3 bits (70), Expect = 1.9
 Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%)
 Frame = +1

Query: 664 GPCDPVFDNMVAQG-LVQPVFSFYLN 738
           G   P+FDN+++QG L + VFSFY N
Sbjct: 97  GRVTPIFDNIISQGVLKEDVFSFYYN 122


>BC042578-1|AAH42578.1|  104|Homo sapiens PGC protein protein.
          Length = 104

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 24/35 (68%), Positives = 30/35 (85%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNL 383
           EP++ Y+DA Y+G ISIGTPPQ+F V+FDTGSS L
Sbjct: 64  EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSPL 97


>AL365205-2|CAI95135.1|  140|Homo sapiens progastricsin (pepsinogen
           C) protein.
          Length = 140

 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 19/44 (43%), Positives = 29/44 (65%)
 Frame = +2

Query: 545 VGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVT 676
           V  ++V  Q F  + +EPG  FV A+FDGI+G+A+  ++VD  T
Sbjct: 71  VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 114


>BC014453-1|AAH14453.1|  518|Homo sapiens beta-site APP-cleaving
           enzyme 2 protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AY358927-1|AAQ89286.1|  518|Homo sapiens BACE2 protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF212252-1|AAG41783.1|  439|Homo sapiens CDA13 protein.
          Length = 439

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 13  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66

Query: 489 AIQY 500
            ++Y
Sbjct: 67  TVKY 70


>AF204944-1|AAF26368.1|  518|Homo sapiens transmembrane aspartic
           proteinase Asp 1 protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF200342-1|AAF17078.1|  518|Homo sapiens aspartyl protease 1
           protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF200192-1|AAF13714.1|  518|Homo sapiens memapsin 1 protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF188277-1|AAF35836.1|  396|Homo sapiens aspartyl protease protein.
          Length = 396

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF188276-1|AAF35835.1|  468|Homo sapiens aspartyl protease protein.
          Length = 468

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF178532-1|AAF29494.1|  518|Homo sapiens aspartyl protease protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF117892-1|AAD45240.1|  518|Homo sapiens aspartic-like protease
           protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AF050171-1|AAD45963.1|  518|Homo sapiens aspartyl protease protein.
          Length = 518

 Score = 42.3 bits (95), Expect = 0.002
 Identities = 22/64 (34%), Positives = 33/64 (51%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 488
           YY  + IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G   
Sbjct: 92  YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145

Query: 489 AIQY 500
            ++Y
Sbjct: 146 TVKY 149


>AK075539-1|BAC11682.1|  423|Homo sapiens protein ( Homo sapiens
           cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
           Homo sapiens aspartyl protease mRNA. ).
          Length = 423

 Score = 39.5 bits (88), Expect = 0.012
 Identities = 20/58 (34%), Positives = 30/58 (51%)
 Frame = +3

Query: 327 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQY 500
           IGTPPQ  +++ DTGSSN  V      Y      +   +D+ +S TY + G    ++Y
Sbjct: 3   IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKY 54


>DQ007053-1|AAY16982.1|  501|Homo sapiens beta-site APP-cleaving
           enzyme 1 protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>BC065492-1|AAH65492.1|  501|Homo sapiens beta-site APP-cleaving
           enzyme 1 protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF338817-1|AAK38375.1|  457|Homo sapiens beta-site APP cleaving
           enzyme type C protein.
          Length = 457

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF338816-1|AAK38374.1|  476|Homo sapiens beta-site APP cleaving
           enzyme type B protein.
          Length = 476

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF204943-1|AAF26367.1|  501|Homo sapiens transmembrane aspartic
           proteinase Asp 2 protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF201468-1|AAF18982.1|  501|Homo sapiens APP beta-secretase
           protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF200343-1|AAF17079.1|  501|Homo sapiens aspartyl protease 2
           protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AF200193-1|AAF13715.1|  488|Homo sapiens memapsin 2 protein.
          Length = 488

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 62  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 108


>AF190725-1|AAF04142.1|  501|Homo sapiens beta-site APP cleaving
           enzyme protein.
          Length = 501

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AB089958-1|BAC81826.1|  127|Homo sapiens beta-site APP cleaving
           enzyme isoform I-127 protein.
          Length = 127

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AB050438-1|BAB40933.1|  432|Homo sapiens beta-site APP cleaving
           enzyme I-432 protein.
          Length = 432

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AB050437-1|BAB40932.1|  457|Homo sapiens beta-site APP cleaving
           enzyme I-457 protein.
          Length = 457

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AB050436-1|BAB40931.1|  476|Homo sapiens beta-site APP cleaving
           enzyme I-476 protein.
          Length = 476

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121


>AB032975-1|BAA86463.2|  532|Homo sapiens KIAA1149 protein protein.
          Length = 532

 Score = 36.7 bits (81), Expect = 0.087
 Identities = 19/53 (35%), Positives = 29/53 (54%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 467
           YY  +++G+PPQ+  ++ DTGSSN  V +    +      LH  Y  + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 152


>BC036084-1|AAH36084.1|  501|Homo sapiens beta-site APP-cleaving
           enzyme 1 protein.
          Length = 501

 Score = 34.7 bits (76), Expect = 0.35
 Identities = 13/27 (48%), Positives = 20/27 (74%)
 Frame = +3

Query: 309 YYGVISIGTPPQSFKVVFDTGSSNLWV 389
           YY  +++G+PPQ+  ++ DTGSSN  V
Sbjct: 75  YYVEMTVGSPPQTLNILVDTGSSNFAV 101


>BC038117-1|AAH38117.1|  317|Homo sapiens LAPTM4B protein protein.
          Length = 317

 Score = 33.5 bits (73), Expect = 0.81
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGCRTCCA 430
           R   R G  +RR++    C    A
Sbjct: 63  RQQRRGGLQARRSTLLKTCARASA 86


>BC110345-1|AAI10346.1|  327|Homo sapiens FAM129B protein protein.
          Length = 327

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 217 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 265


>AY261384-1|AAO84265.1|  370|Homo sapiens lysosome-associated
           transmembrane protein 4 beta protein.
          Length = 370

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 59  RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 115

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 116 RQQRRGGLQARRSTLLKTC 134


>AY219177-1|AAO64359.1|  124|Homo sapiens lysosome-associated
           protein transmembrane 4 beta protein.
          Length = 124

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 63  RQQRRGGLQARRSTLLKTC 81


>AY219176-1|AAO64358.1|  124|Homo sapiens lysosome-associated
           protein transmembrane 4 beta protein.
          Length = 124

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 63  RQQRRGGLQARRSTLLKTC 81


>AY198226-1|AAO63563.1|  124|Homo sapiens LAPTM4B protein.
          Length = 124

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 63  RQQRRGGLQARRSTLLKTC 81


>AY057051-1|AAL17908.2|  317|Homo sapiens lysosomal associated
           transmembrane protein 4 beta, variant 1 protein.
          Length = 317

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 63  RQQRRGGLQARRSTLLKTC 81


>AL445222-2|CAH72915.1|  733|Homo sapiens family with sequence
           similarity 129, member B protein.
          Length = 733

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 623 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 671


>AL445222-1|CAH72914.1|  746|Homo sapiens family with sequence
           similarity 129, member B protein.
          Length = 746

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 636 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 684


>AL390116-2|CAH73085.1|  733|Homo sapiens family with sequence
           similarity 129, member B protein.
          Length = 733

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 623 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 671


>AL390116-1|CAH73084.1|  746|Homo sapiens family with sequence
           similarity 129, member B protein.
          Length = 746

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 636 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 684


>AK025804-1|BAB15240.1|  201|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ22151 fis, clone HRC00111. ).
          Length = 201

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 91  EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 139


>AK023580-1|BAB14615.1|  396|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13518 fis, clone PLACE1005799. ).
          Length = 396

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 286 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 334


>AF527412-1|AAP14034.1|  317|Homo sapiens lysosomal associated
           transmembrane protein 4 beta variant 2 protein.
          Length = 317

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
 Frame = -2

Query: 678 RVTWSTAIVLKAIPRIPSNLAATKASPGSDTASANVWRRTLSP-PTVTSSVERKPERLRS 502
           RVTW +    + +P +P+  A    + G+D A A   R      P       R+PER RS
Sbjct: 6   RVTWPSPP--RPLP-VPAAAAVAFGAKGTDPAEARSSRGIEEAGPRAHGRAGREPERRRS 62

Query: 501 RTVSRTGCHSRRTSWTCGC 445
           R   R G  +RR++    C
Sbjct: 63  RQQRRGGLQARRSTLLKTC 81


>AF192911-1|AAQ13825.1|  746|Homo sapiens OC58 protein.
          Length = 746

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 636 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 684


>AF151783-1|AAK57556.1|  733|Homo sapiens MEG3 protein.
          Length = 733

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 623 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 671


>AB210016-1|BAE06098.1|  739|Homo sapiens C9orf88 variant protein
           protein.
          Length = 739

 Score = 33.1 bits (72), Expect = 1.1
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 629 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 677


>AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular
           protein PACT protein.
          Length = 1625

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = -2

Query: 639 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVS-RTGCHSRRT 463
           P  P+NL+    S G  TA +N    T +PP       R+  RL+  + S  +G    R+
Sbjct: 472 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRS 531

Query: 462 SWT 454
           S+T
Sbjct: 532 SYT 534


>AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding
           protein 6 isoform 2 protein.
          Length = 1758

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = -2

Query: 639 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVS-RTGCHSRRT 463
           P  P+NL+    S G  TA +N    T +PP       R+  RL+  + S  +G    R+
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRS 664

Query: 462 SWT 454
           S+T
Sbjct: 665 SYT 667


>BC001979-1|AAH01979.2|  456|Homo sapiens FAM129B protein protein.
          Length = 456

 Score = 32.3 bits (70), Expect = 1.9
 Identities = 17/50 (34%), Positives = 25/50 (50%)
 Frame = -1

Query: 649 EGHPEDPVELGGHEGKPGLRHGLGERLAPHLEPAHGDIISGEEAGEAPEP 500
           E  PE P      +G   +R  L + L P   P  G +++G  AGE+P+P
Sbjct: 346 EASPESPPP-ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGALAGESPQP 394


>BC030606-1|AAH30606.2|  514|Homo sapiens coiled-coil domain
           containing 11 protein.
          Length = 514

 Score = 30.7 bits (66), Expect = 5.7
 Identities = 12/26 (46%), Positives = 18/26 (69%)
 Frame = -3

Query: 374 GSGVEYHLERLRRRADTDHSVVLSIK 297
           G G E+HLER+RR     ++++ SIK
Sbjct: 30  GQGAEHHLERIRRSHQKHNAILASIK 55


>AL365205-3|CAM16152.1|   86|Homo sapiens progastricsin (pepsinogen
           C) protein.
          Length = 86

 Score = 30.7 bits (66), Expect = 5.7
 Identities = 13/20 (65%), Positives = 17/20 (85%)
 Frame = +3

Query: 279 EPLSNYLDAQYYGVISIGTP 338
           EP++ Y+DA Y+G ISIGTP
Sbjct: 68  EPMA-YMDAAYFGEISIGTP 86


>U31468-1|AAC03241.1|  347|Homo sapiens homeobox protein protein.
          Length = 347

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 2/97 (2%)
 Frame = -2

Query: 612 TKASPGSDTASANVWRRTLSPP--TVTSSVERKPERLRSRTVSRTGCHSRRTSWTCGCRT 439
           T  SP    ASA  WRR    P  +   S    P R  +R   R    SRR+     C  
Sbjct: 80  TTRSPACPQASAPAWRRAWRSPLRSWPRSPAASPRRPSTRRRQRP-ASSRRSR----CPA 134

Query: 438 CCAANKRCWCSGTFWKAPRGWRIRCRIPP*TTAAACR 328
              + +R  C  T   A   W  R R  P      CR
Sbjct: 135 AVTSTRRRRCRLTRRTAKASWPKRARCSPSPRPRRCR 171


>BC112259-1|AAI12260.1|  591|Homo sapiens MAGEL2 protein protein.
          Length = 591

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 188 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 241


>BC112257-1|AAI12258.1|  591|Homo sapiens MAGEL2 protein protein.
          Length = 591

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 188 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 241


>BC063834-1|AAH63834.1|  677|Homo sapiens MAGEL2 protein protein.
          Length = 677

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 274 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 327


>BC035839-1|AAH35839.1|  657|Homo sapiens MAGEL2 protein protein.
          Length = 657

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 254 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 307


>AJ243531-1|CAB62393.1|  529|Homo sapiens nM15 protein protein.
          Length = 529

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 126 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 179


>AF200625-1|AAG28577.1|  529|Homo sapiens necdin-like protein 1
           protein.
          Length = 529

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = -2

Query: 648 KAIPRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLRSRTVSR 487
           KA   +P+ L AT A+P +   +    + ++ PP  +    RK + L ++  SR
Sbjct: 126 KASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSR 179


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,077,251
Number of Sequences: 237096
Number of extensions: 2528302
Number of successful extensions: 7522
Number of sequences better than 10.0: 97
Number of HSP's better than 10.0 without gapping: 6634
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7475
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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