Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbVm0327
(733 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B59A5 Cluster: PREDICTED: similar to ENSANGP000... 133 4e-30
UniRef50_Q4S6Y9 Cluster: Chromosome 14 SCAF14723, whole genome s... 122 7e-27
UniRef50_P11586 Cluster: C-1-tetrahydrofolate synthase, cytoplas... 116 8e-25
UniRef50_Q9LHH7 Cluster: 5,10-methylenetetrahydrofolate dehydrog... 109 5e-23
UniRef50_O65271 Cluster: F6N23.26 protein; n=20; Viridiplantae|R... 108 1e-22
UniRef50_O65269 Cluster: F6N23.28 protein; n=1; Arabidopsis thal... 103 6e-21
UniRef50_Q4T2B9 Cluster: Chromosome undetermined SCAF10300, whol... 101 2e-20
UniRef50_Q9SPK5 Cluster: Formate--tetrahydrofolate ligase; n=105... 96 7e-19
UniRef50_A7P012 Cluster: Chromosome chr6 scaffold_3, whole genom... 95 2e-18
UniRef50_Q8W528 Cluster: Methylenetetrahydrofolate dehydrogenase... 95 2e-18
UniRef50_Q3YRE3 Cluster: Bifunctional protein folD [Includes: Me... 90 6e-17
UniRef50_Q21285 Cluster: Dauer or aging adult overexpression pro... 87 3e-16
UniRef50_Q86F84 Cluster: Clone ZZD1003 mRNA sequence; n=1; Schis... 85 2e-15
UniRef50_Q9A8Y0 Cluster: Bifunctional protein folD [Includes: Me... 84 3e-15
UniRef50_A7D6I9 Cluster: Methenyltetrahydrofolate cyclohydrolase... 83 5e-15
UniRef50_UPI000065DF90 Cluster: methylenetetrahydrofolate dehydr... 82 1e-14
UniRef50_Q7MVE9 Cluster: Bifunctional protein folD [Includes: Me... 82 1e-14
UniRef50_Q8DMU0 Cluster: Bifunctional protein folD [Includes: Me... 81 3e-14
UniRef50_Q81RE1 Cluster: Formate--tetrahydrofolate ligase; n=48;... 81 4e-14
UniRef50_A5V1H2 Cluster: Methylenetetrahydrofolate dehydrogenase... 80 5e-14
UniRef50_Q87HX2 Cluster: Formate--tetrahydrofolate ligase; n=65;... 80 5e-14
UniRef50_Q5PBL6 Cluster: Bifunctional protein folD [Includes: Me... 80 5e-14
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 80 6e-14
UniRef50_Q16F77 Cluster: Methylenetetrahydrofolate dehydrogenase... 80 6e-14
UniRef50_Q6F9E6 Cluster: Bifunctional protein folD 1 [Includes: ... 80 6e-14
UniRef50_UPI00006CCCC6 Cluster: methylenetetrahydrofolate dehydr... 79 8e-14
UniRef50_P13995 Cluster: Bifunctional methylenetetrahydrofolate ... 79 8e-14
UniRef50_A1AL91 Cluster: Bifunctional protein folD [Includes: Me... 79 8e-14
UniRef50_Q6ABS5 Cluster: Formate--tetrahydrofolate ligase; n=52;... 79 1e-13
UniRef50_Q6ALZ5 Cluster: Bifunctional protein folD [Includes: Me... 79 1e-13
UniRef50_A1SQH3 Cluster: Formate--tetrahydrofolate ligase; n=38;... 78 2e-13
UniRef50_UPI000038C811 Cluster: COG0190: 5,10-methylene-tetrahyd... 78 3e-13
UniRef50_O83714 Cluster: Bifunctional protein folD [Includes: Me... 77 3e-13
UniRef50_Q6D2E6 Cluster: Bifunctional protein folD [Includes: Me... 77 4e-13
UniRef50_Q4FNW1 Cluster: Bifunctional protein folD [Includes: Me... 77 6e-13
UniRef50_Q9HPY4 Cluster: Bifunctional protein folD [Includes: Me... 76 8e-13
UniRef50_UPI0000DB7ABF Cluster: PREDICTED: similar to Bifunction... 76 1e-12
UniRef50_A5WI04 Cluster: Formate--tetrahydrofolate ligase; n=5; ... 76 1e-12
UniRef50_Q8Y624 Cluster: Formate--tetrahydrofolate ligase; n=71;... 75 2e-12
UniRef50_Q5SJ94 Cluster: Bifunctional protein folD [Includes: Me... 75 2e-12
UniRef50_Q987T6 Cluster: Bifunctional protein folD 2 [Includes: ... 74 3e-12
UniRef50_Q5V5Y2 Cluster: Formate--tetrahydrofolate ligase; n=406... 74 4e-12
UniRef50_Q8KN38 Cluster: Bifunctional protein folD [Includes: Me... 74 4e-12
UniRef50_Q54VK0 Cluster: Methenyl tetrahydrofolate cyclohydrolas... 73 1e-11
UniRef50_Q5FJY2 Cluster: Formate--tetrahydrofolate ligase 1; n=5... 73 1e-11
UniRef50_Q2B9L0 Cluster: Bifunctional protein FolD; n=1; Bacillu... 72 2e-11
UniRef50_Q9KQQ6 Cluster: Bifunctional protein folD [Includes: Me... 72 2e-11
UniRef50_Q057D7 Cluster: Bifunctional protein folD [Includes: Me... 70 7e-11
UniRef50_A6NP56 Cluster: Uncharacterized protein ENSP00000372121... 69 9e-11
UniRef50_Q4FTX6 Cluster: Bifunctional protein folD [Includes: Me... 69 9e-11
UniRef50_A6CAY4 Cluster: Formate--tetrahydrofolate ligase; n=3; ... 69 1e-10
UniRef50_A7DNA7 Cluster: Methylenetetrahydrofolate dehydrogenase... 69 1e-10
UniRef50_Q3ZX40 Cluster: Formate--tetrahydrofolate ligase; n=12;... 69 2e-10
UniRef50_UPI00005A5066 Cluster: PREDICTED: similar to Bifunction... 68 2e-10
UniRef50_Q8EQ43 Cluster: Bifunctional protein folD [Includes: Me... 68 2e-10
UniRef50_Q7TU81 Cluster: Bifunctional protein folD [Includes: Me... 68 3e-10
UniRef50_Q1II76 Cluster: Bifunctional protein folD [Includes: Me... 68 3e-10
UniRef50_Q1AVQ0 Cluster: Bifunctional protein folD 2 [Includes: ... 68 3e-10
UniRef50_Q74J95 Cluster: Bifunctional protein folD 1 [Includes: ... 68 3e-10
UniRef50_Q1DFW5 Cluster: Formate--tetrahydrofolate ligase; n=2; ... 67 4e-10
UniRef50_Q63SL6 Cluster: Bifunctional protein folD [Includes: Me... 67 4e-10
UniRef50_Q83FS2 Cluster: Bifunctional protein folD [Includes: Me... 65 1e-09
UniRef50_O84081 Cluster: Bifunctional protein folD [Includes: Me... 65 1e-09
UniRef50_P56467 Cluster: Bifunctional protein folD [Includes: Me... 65 2e-09
UniRef50_Q4DH06 Cluster: Methylenetetrahydrofolate dehydrogenase... 64 3e-09
UniRef50_A0DMT9 Cluster: Chromosome undetermined scaffold_57, wh... 64 3e-09
UniRef50_A0JTZ0 Cluster: Bifunctional protein folD [Includes: Me... 64 3e-09
UniRef50_Q8TK95 Cluster: Bifunctional protein folD [Includes: Me... 64 3e-09
UniRef50_A0C3Q0 Cluster: Chromosome undetermined scaffold_147, w... 63 6e-09
UniRef50_Q9PQS1 Cluster: Formate--tetrahydrofolate ligase; n=1; ... 63 6e-09
UniRef50_Q5FJG5 Cluster: Bifunctional protein folD [Includes: Me... 63 6e-09
UniRef50_Q3AYX2 Cluster: Bifunctional protein folD [Includes: Me... 62 1e-08
UniRef50_Q6MI74 Cluster: Bifunctional protein folD [Includes: Me... 62 1e-08
UniRef50_Q2JCX4 Cluster: Bifunctional protein folD 1 [Includes: ... 62 1e-08
UniRef50_Q9ZD32 Cluster: Bifunctional protein folD [Includes: Me... 62 1e-08
UniRef50_Q24UZ7 Cluster: Bifunctional protein folD 2 [Includes: ... 61 2e-08
UniRef50_Q74GN1 Cluster: Bifunctional protein folD 1 [Includes: ... 61 3e-08
UniRef50_A3EUA4 Cluster: Formyltetrahydrofolate synthetase; n=2;... 60 4e-08
UniRef50_Q6F1V0 Cluster: Bifunctional protein folD [Includes: Me... 60 4e-08
UniRef50_Q8RDM4 Cluster: Bifunctional protein folD [Includes: Me... 60 7e-08
UniRef50_Q8RAD0 Cluster: Bifunctional protein folD [Includes: Me... 58 2e-07
UniRef50_Q4A6B1 Cluster: Bifunctional protein folD [Includes: Me... 58 3e-07
UniRef50_A4EAK0 Cluster: Putative uncharacterized protein; n=3; ... 57 5e-07
UniRef50_Q979W3 Cluster: Bifunctional protein folD [Includes: Me... 57 5e-07
UniRef50_Q97CL3 Cluster: Formate--tetrahydrofolate ligase; n=4; ... 56 7e-07
UniRef50_Q0SFQ8 Cluster: Bifunctional protein folD 1 [Includes: ... 56 1e-06
UniRef50_A1HML1 Cluster: Methenyltetrahydrofolate cyclohydrolase... 55 2e-06
UniRef50_A5CF58 Cluster: Bifunctional protein folD [Includes: Me... 55 2e-06
UniRef50_Q14NV0 Cluster: Probable formate-tetrahydrofolate ligas... 55 2e-06
UniRef50_Q6KID0 Cluster: Bifunctional protein folD [Includes: Me... 55 2e-06
UniRef50_Q9X288 Cluster: Bifunctional protein folD [Includes: Me... 54 3e-06
UniRef50_Q14NV1 Cluster: Bifunctional protein folD [Includes: Me... 54 4e-06
UniRef50_Q3A1Q7 Cluster: Bifunctional protein folD [Includes: Me... 54 4e-06
UniRef50_Q7NAE4 Cluster: Bifunctional protein folD [Includes: Me... 53 6e-06
UniRef50_A4M873 Cluster: Tetrahydrofolate dehydrogenase/cyclohyd... 52 1e-05
UniRef50_Q8EUQ1 Cluster: Formate--tetrahydrofolate ligase; n=1; ... 52 1e-05
UniRef50_A3PVV6 Cluster: Bifunctional protein folD [Includes: Me... 52 1e-05
UniRef50_UPI00006CB712 Cluster: tetrahydrofolate dehydrogenase/c... 52 2e-05
UniRef50_Q97HC9 Cluster: Bifunctional protein folD [Includes: Me... 52 2e-05
UniRef50_Q189R8 Cluster: Bifunctional protein folD [Includes: Me... 51 3e-05
UniRef50_O51057 Cluster: Bifunctional protein folD [Includes: Me... 50 4e-05
UniRef50_Q04FB7 Cluster: Bifunctional protein folD [Includes: Me... 48 2e-04
UniRef50_A5IXS7 Cluster: FolD bifunctional protein; n=1; Mycopla... 48 3e-04
UniRef50_Q9RW02 Cluster: Bifunctional protein folD [Includes: Me... 48 3e-04
UniRef50_Q6L046 Cluster: Bifunctional protein folD [Includes: Me... 45 0.002
UniRef50_Q8EV80 Cluster: Bifunctional protein folD [Includes: Me... 45 0.002
UniRef50_A6LP88 Cluster: Tetrahydrofolate dehydrogenase/cyclohyd... 42 0.016
UniRef50_A1ZUI3 Cluster: Tetrahydrofolate dehydrogenase/cyclohyd... 41 0.027
UniRef50_Q8ZZK1 Cluster: Bifunctional protein folD [Includes: Me... 41 0.036
UniRef50_A1ALK9 Cluster: Hydrogenase maturation protease; n=1; P... 40 0.063
UniRef50_A5CR60 Cluster: DNA polymerase III, alpha chain; n=2; M... 39 0.15
UniRef50_A7AXK7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.19
UniRef50_Q0AZF5 Cluster: Bifunctional protein folD 1 [Includes: ... 38 0.19
UniRef50_Q1Q6L6 Cluster: Similar to copper oxidase and hydroxyla... 36 1.0
UniRef50_Q6NN19 Cluster: RE04973p; n=4; Sophophora|Rep: RE04973p... 36 1.0
UniRef50_UPI00015B5313 Cluster: PREDICTED: similar to CG1718-PA;... 36 1.4
UniRef50_Q0UU61 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_P47259 Cluster: Bifunctional protein folD [Includes: Me... 36 1.4
UniRef50_UPI0000DD8491 Cluster: PREDICTED: hypothetical protein;... 35 1.8
UniRef50_Q16NN2 Cluster: Brachyury; n=2; Culicidae|Rep: Brachyur... 35 1.8
UniRef50_A4S4Y5 Cluster: Predicted protein; n=2; Ostreococcus|Re... 35 2.4
UniRef50_Q2PPB3 Cluster: Histidine biosynthesis trifunctional pr... 35 2.4
UniRef50_Q0AWX5 Cluster: Bifunctional protein folD 2 [Includes: ... 35 2.4
UniRef50_Q4FXT5 Cluster: Putative uncharacterized protein; n=3; ... 34 3.1
UniRef50_P07685 Cluster: Histidine biosynthesis trifunctional pr... 34 3.1
UniRef50_UPI0000E2417F Cluster: PREDICTED: hypothetical protein;... 34 4.1
UniRef50_Q55365 Cluster: Endo-1,4-beta-glucanase; n=1; Synechocy... 34 4.1
UniRef50_A7EN88 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1
UniRef50_UPI00004EBBDF Cluster: Hypothetical protein MuHV1gpm30;... 33 5.5
UniRef50_Q4T9M8 Cluster: Chromosome undetermined SCAF7533, whole... 33 5.5
UniRef50_Q91TP2 Cluster: T47; n=1; Tupaiid herpesvirus 1|Rep: T4... 33 5.5
UniRef50_Q08SH7 Cluster: Translation initiation factor SUI1 fami... 33 5.5
UniRef50_A7DDM2 Cluster: Smr protein/MutS2; n=2; Methylobacteriu... 33 5.5
UniRef50_A1WX06 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q6YXJ2 Cluster: Putative uncharacterized protein B1029H... 33 5.5
UniRef50_Q5CN90 Cluster: Last step in pyrimidine biosynthesis pa... 33 5.5
UniRef50_Q7S5B5 Cluster: Putative uncharacterized protein NCU022... 33 5.5
UniRef50_A3LSS5 Cluster: Histidine biosynthesis trifunctional pr... 33 5.5
UniRef50_P00815 Cluster: Histidine biosynthesis trifunctional pr... 33 5.5
UniRef50_UPI0000E24696 Cluster: PREDICTED: hypothetical protein;... 33 7.2
UniRef50_Q14839-2 Cluster: Isoform 2 of Q14839 ; n=19; Euteleost... 33 7.2
UniRef50_Q2LXV3 Cluster: Methyl-viologen-reducing hydrogenase, d... 33 7.2
UniRef50_Q0EZ74 Cluster: Translation initiation factor IF-2; n=1... 33 7.2
UniRef50_Q02AS0 Cluster: Putative uncharacterized protein precur... 33 7.2
UniRef50_A4X3P9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_A4VQJ8 Cluster: Transcriptional regulator, AraC family;... 33 7.2
UniRef50_Q75I35 Cluster: Putative uncharacterized protein Os03g4... 33 7.2
UniRef50_Q4D315 Cluster: Putative uncharacterized protein; n=2; ... 33 7.2
UniRef50_A5K1V8 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_Q9UMR3 Cluster: T-box transcription factor TBX20; n=34;... 33 7.2
UniRef50_UPI0000EBEFAE Cluster: PREDICTED: hypothetical protein,... 33 9.5
UniRef50_UPI000023D465 Cluster: hypothetical protein FG10402.1; ... 33 9.5
UniRef50_Q13H21 Cluster: Putative FAD dependent oxidoreductase; ... 33 9.5
UniRef50_A3VQT7 Cluster: ATP-dependent protease peptidase subuni... 33 9.5
UniRef50_Q6ATH5 Cluster: Putative uncharacterized protein OSJNBa... 33 9.5
UniRef50_Q00SR1 Cluster: 10-formyltetra; n=1; Ostreococcus tauri... 33 9.5
UniRef50_A4H9T3 Cluster: Protein kinase; n=1; Leishmania brazili... 33 9.5
UniRef50_Q4PBD7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_Q2HFX2 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
UniRef50_A7F9H5 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
>UniRef50_UPI00015B59A5 Cluster: PREDICTED: similar to
ENSANGP00000016878; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000016878 - Nasonia
vitripennis
Length = 866
Score = 133 bits (322), Expect = 4e-30
Identities = 62/84 (73%), Positives = 71/84 (84%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGAVVIDCGIN+I DPTKKSGQRLVGDV Y EA KVAS +TPVPGGVGPMTVAMLM+
Sbjct: 228 WIKPGAVVIDCGINSIPDPTKKSGQRLVGDVDYAEAAKVASYITPVPGGVGPMTVAMLMK 287
Query: 183 NTVQAARRQLDRLLAPSWPLKPLR 254
NTV +A+R +RLL W ++ L+
Sbjct: 288 NTVISAQRAAERLLHNDWKVRVLK 311
Score = 111 bits (267), Expect = 2e-23
Identities = 52/81 (64%), Positives = 66/81 (81%)
Frame = +2
Query: 269 PPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVV 448
P PSDI I+R+ +PK I +A EIG+ P+E+S YG KAKI LSV+ RL++Q+ GKY+VV
Sbjct: 317 PVPSDIAISRAHEPKPITMIAEEIGVLPNELSPYGSKKAKIGLSVIKRLQHQKDGKYVVV 376
Query: 449 AGITPTPLGEGKSTTLIGLVK 511
AGITPTPLGEGKSTT +GLV+
Sbjct: 377 AGITPTPLGEGKSTTSLGLVQ 397
Score = 111 bits (266), Expect = 2e-23
Identities = 50/65 (76%), Positives = 57/65 (87%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANN 687
+ALTAH+GKN+FA +RQPSQGPTFGVK Y+QVIPMEEFNLH+TGDIHAVTAANN
Sbjct: 397 QALTAHKGKNSFATLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAVTAANN 456
Query: 688 LLAAQ 702
L+AAQ
Sbjct: 457 LMAAQ 461
>UniRef50_Q4S6Y9 Cluster: Chromosome 14 SCAF14723, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF14723, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1066
Score = 122 bits (295), Expect = 7e-27
Identities = 57/87 (65%), Positives = 69/87 (79%)
Frame = +2
Query: 251 SLTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRT 430
SL P+TP PSDI I+R+ PK + +LA EIGL P E+ YGR+KAK+ LS+LDRL NQ
Sbjct: 269 SLQPLTPVPSDIEISRAHTPKPVSQLAKEIGLLPEELEVYGRSKAKVRLSLLDRLHNQPD 328
Query: 431 GKYIVVAGITPTPLGEGKSTTLIGLVK 511
GKY++VAGITPTPLGEGKST IGLV+
Sbjct: 329 GKYVLVAGITPTPLGEGKSTVTIGLVQ 355
Score = 87.0 bits (206), Expect = 4e-16
Identities = 43/70 (61%), Positives = 52/70 (74%), Gaps = 6/70 (8%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXX------YSQVIPMEEFNLHMTGDIHA 669
+AL+AH N+FAC+RQPSQGPTF + Y+QVIPMEEFNLH+TGDIHA
Sbjct: 355 QALSAHLKLNSFACLRQPSQGPTFWGESNLLCLGGAAGGGYAQVIPMEEFNLHLTGDIHA 414
Query: 670 VTAANNLLAA 699
+TAANNL+AA
Sbjct: 415 ITAANNLVAA 424
>UniRef50_P11586 Cluster: C-1-tetrahydrofolate synthase, cytoplasmic
(C1-THF synthase) [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
synthetase (EC 6.3.4.3)]; n=86; cellular organisms|Rep:
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF
synthase) [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate
synthetase (EC 6.3.4.3)] - Homo sapiens (Human)
Length = 935
Score = 116 bits (278), Expect = 8e-25
Identities = 72/158 (45%), Positives = 88/158 (55%), Gaps = 2/158 (1%)
Frame = +2
Query: 266 TPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIV 445
TP PSDI I+RS KPK IG+LA EIGL EV YG TKAK+ LS L+RL+++ GKY+V
Sbjct: 314 TPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVV 373
Query: 446 VAGITPTPLGEGKSTTLIGLVKR-*QHIAGRTRLHACGNRVRDRP-LALKGVLLEGATLK 619
V GITPTPLGEGKSTT IGLV+ H+ + AC + P +KG G +
Sbjct: 374 VTGITPTPLGEGKSTTTIGLVQALGAHL--YQNVFACVRQPSQGPTFGIKGGAAGGGYSQ 431
Query: 620 *FQWRSSTCT*LATFMP*PLPTIFLLHKMDARIFHELT 733
+ +DARIFHELT
Sbjct: 432 VIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELT 469
Score = 110 bits (264), Expect = 4e-23
Identities = 48/81 (59%), Positives = 65/81 (80%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA+VIDCGIN + D K +G+++VGDVAY EA + AS +TPVPGGVGPMTVAMLM+
Sbjct: 226 WIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQ 285
Query: 183 NTVQAARRQLDRLLAPSWPLK 245
+TV++A+R L++ W ++
Sbjct: 286 STVESAKRFLEKFKPGKWMIQ 306
Score = 102 bits (245), Expect = 8e-21
Identities = 46/64 (71%), Positives = 53/64 (82%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANN 687
+AL AH +N FAC+RQPSQGPTFG+K YSQVIPMEEFNLH+TGDIHA+TAANN
Sbjct: 395 QALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANN 454
Query: 688 LLAA 699
L+AA
Sbjct: 455 LVAA 458
>UniRef50_Q9LHH7 Cluster: 5,10-methylenetetrahydrofolate
dehydrogenase/5,10- methenyltetrahydrofolate
cyclohydrolase; n=7; Eukaryota|Rep:
5,10-methylenetetrahydrofolate dehydrogenase/5,10-
methenyltetrahydrofolate cyclohydrolase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 299
Score = 109 bits (263), Expect = 5e-23
Identities = 50/68 (73%), Positives = 56/68 (82%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA VID G NA+ DP+KKSG RLVGDV + EA KVA +TPVPGGVGPMTVAML+R
Sbjct: 228 WIKPGAAVIDVGTNAVSDPSKKSGYRLVGDVDFAEASKVAGFITPVPGGVGPMTVAMLLR 287
Query: 183 NTVQAARR 206
NTV A+R
Sbjct: 288 NTVDGAKR 295
>UniRef50_O65271 Cluster: F6N23.26 protein; n=20; Viridiplantae|Rep:
F6N23.26 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 360
Score = 108 bits (260), Expect = 1e-22
Identities = 47/68 (69%), Positives = 58/68 (85%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGAV+ID GIN +EDP+ G RLVGD+ Y+EA KVASA+TPVPGGVGPMT+AML+
Sbjct: 288 WIKPGAVLIDVGINPVEDPSAARGYRLVGDICYEEASKVASAITPVPGGVGPMTIAMLLS 347
Query: 183 NTVQAARR 206
NT+ +A+R
Sbjct: 348 NTLTSAKR 355
>UniRef50_O65269 Cluster: F6N23.28 protein; n=1; Arabidopsis
thaliana|Rep: F6N23.28 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 310
Score = 103 bits (246), Expect = 6e-21
Identities = 44/68 (64%), Positives = 56/68 (82%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGAV+ID GI +EDP+ G+RLVGD+ Y EA K+ASA+TPVPG VGPMT+AML+
Sbjct: 238 WIKPGAVLIDVGIKPVEDPSAAGGERLVGDICYVEASKIASAITPVPGDVGPMTIAMLLS 297
Query: 183 NTVQAARR 206
NT+ +A+R
Sbjct: 298 NTLTSAKR 305
>UniRef50_Q4T2B9 Cluster: Chromosome undetermined SCAF10300, whole
genome shotgun sequence; n=6; Clupeocephala|Rep:
Chromosome undetermined SCAF10300, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 348
Score = 101 bits (242), Expect = 2e-20
Identities = 46/72 (63%), Positives = 58/72 (80%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
W+K GAVVIDCGIN + D T+ SG+R+VGDV Y A + A +TPVPGGVGPMTVAMLM+
Sbjct: 272 WLKEGAVVIDCGINQVPDCTRASGKRVVGDVHYASAHQRAGFITPVPGGVGPMTVAMLMQ 331
Query: 183 NTVQAARRQLDR 218
NTV++A+R L +
Sbjct: 332 NTVRSAQRYLSK 343
>UniRef50_Q9SPK5 Cluster: Formate--tetrahydrofolate ligase; n=105;
root|Rep: Formate--tetrahydrofolate ligase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 634
Score = 96.3 bits (229), Expect = 7e-19
Identities = 45/91 (49%), Positives = 60/91 (65%)
Frame = +2
Query: 233 LASETASLTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDR 412
++S T L ++P P+DI IA S +P I E+A ++ + P YG+ KAK+ LS D
Sbjct: 1 MSSSTRKLEVVSPVPADIDIANSVEPLHISEIAKDLNINPLHYDLYGKYKAKVLLSAFDE 60
Query: 413 LRNQRTGKYIVVAGITPTPLGEGKSTTLIGL 505
L+ Q G Y+VV GITPTPLGEGKSTT +GL
Sbjct: 61 LQGQEDGYYVVVGGITPTPLGEGKSTTTVGL 91
Score = 95.1 bits (226), Expect = 2e-18
Identities = 42/64 (65%), Positives = 50/64 (78%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANN 687
+AL A+ K C+RQPSQGPTFG+K YSQVIPM+EFNLH+TGDIHA+TA+NN
Sbjct: 93 QALGAYLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITASNN 152
Query: 688 LLAA 699
LLAA
Sbjct: 153 LLAA 156
>UniRef50_A7P012 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 594
Score = 95.1 bits (226), Expect = 2e-18
Identities = 43/64 (67%), Positives = 49/64 (76%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANN 687
+AL A K C+RQPSQGPTFG+K YSQVIPM+EFNLH+TGDIHA+TAANN
Sbjct: 96 QALGAFLDKKVVTCLRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANN 155
Query: 688 LLAA 699
LLAA
Sbjct: 156 LLAA 159
Score = 94.3 bits (224), Expect = 3e-18
Identities = 47/84 (55%), Positives = 57/84 (67%)
Frame = +2
Query: 254 LTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTG 433
L ++P P+DI IA S P I E+A E+ L PS YG+ KAK+ LSVLD L+ G
Sbjct: 11 LNVLSPVPADIDIANSVVPFHISEIAQELNLDPSHYDLYGKYKAKVLLSVLDDLQGSGDG 70
Query: 434 KYIVVAGITPTPLGEGKSTTLIGL 505
Y+VV GITPTPLGEGKSTT +GL
Sbjct: 71 YYVVVGGITPTPLGEGKSTTTVGL 94
>UniRef50_Q8W528 Cluster: Methylenetetrahydrofolate
dehydrogenase/methylenetetrahydrofolate cylcohydrolase
isoform 1; n=11; Viridiplantae|Rep:
Methylenetetrahydrofolate
dehydrogenase/methylenetetrahydrofolate cylcohydrolase
isoform 1 - Zea mays (Maize)
Length = 160
Score = 94.7 bits (225), Expect = 2e-18
Identities = 41/55 (74%), Positives = 47/55 (85%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTV 167
WIKPGA VID G NA++DPT+KSG RLVGDV +QEA KVA +TPVPGGVGPMT+
Sbjct: 106 WIKPGAAVIDVGTNAVDDPTRKSGYRLVGDVDFQEACKVAGWITPVPGGVGPMTI 160
>UniRef50_Q3YRE3 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=7; Proteobacteria|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Ehrlichia canis (strain Jake)
Length = 300
Score = 89.8 bits (213), Expect = 6e-17
Identities = 44/69 (63%), Positives = 52/69 (75%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA+VID GIN++E+ K + VGDV + EA VASA+TPVPGGVGPMT+A LM
Sbjct: 222 WIKPGAIVIDVGINSVEEDGVK---KFVGDVNFAEAKNVASAITPVPGGVGPMTIAFLMV 278
Query: 183 NTVQAARRQ 209
NTV AA Q
Sbjct: 279 NTVMAACNQ 287
>UniRef50_Q21285 Cluster: Dauer or aging adult overexpression
protein 3; n=2; Caenorhabditis|Rep: Dauer or aging adult
overexpression protein 3 - Caenorhabditis elegans
Length = 303
Score = 87.4 bits (207), Expect = 3e-16
Identities = 41/69 (59%), Positives = 52/69 (75%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA VIDCGIN +DP + ++ GDV + A +VA +TPVPGGVGPMTVAML+R
Sbjct: 228 WIKPGAFVIDCGINVGDDPNSR---KIYGDVDTEAAKEVAGFLTPVPGGVGPMTVAMLIR 284
Query: 183 NTVQAARRQ 209
NT + A+R+
Sbjct: 285 NTFEQAKRR 293
>UniRef50_Q86F84 Cluster: Clone ZZD1003 mRNA sequence; n=1;
Schistosoma japonicum|Rep: Clone ZZD1003 mRNA sequence -
Schistosoma japonicum (Blood fluke)
Length = 332
Score = 85.0 bits (201), Expect = 2e-15
Identities = 35/67 (52%), Positives = 49/67 (73%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
W++PGA+VIDCG + + DP S R GDV + A++ A +TPVPGGVGP+++AML R
Sbjct: 235 WVRPGALVIDCGYSVMNDPQNPSKSRCFGDVEFNTALEKAKWITPVPGGVGPVSIAMLFR 294
Query: 183 NTVQAAR 203
NTV +A+
Sbjct: 295 NTVNSAQ 301
>UniRef50_Q9A8Y0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=82; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 297
Score = 84.2 bits (199), Expect = 3e-15
Identities = 42/72 (58%), Positives = 51/72 (70%), Gaps = 4/72 (5%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAI--EDPTKKSG--QRLVGDVAYQEAVKVASAVTPVPGGVGPMTVA 170
W+KPGAVVID GI DP + RLVGDVA+ E +VA A+TPVPGGVGPMT+A
Sbjct: 221 WVKPGAVVIDVGITRFPARDPEAAAAGKTRLVGDVAFDEVREVAGAITPVPGGVGPMTIA 280
Query: 171 MLMRNTVQAARR 206
L+ NT+ AA+R
Sbjct: 281 CLLANTLTAAKR 292
>UniRef50_A7D6I9 Cluster: Methenyltetrahydrofolate cyclohydrolase;
n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Methenyltetrahydrofolate cyclohydrolase - Halorubrum
lacusprofundi ATCC 49239
Length = 307
Score = 83.4 bits (197), Expect = 5e-15
Identities = 42/70 (60%), Positives = 51/70 (72%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GA VID GIN ++ T+K G LVGDV Y+ A + A A+TPVPGGVGPMT AML+ N
Sbjct: 233 LKEGATVIDVGINRVDADTEK-GYALVGDVEYESAKEAAGAITPVPGGVGPMTRAMLLYN 291
Query: 186 TVQAARRQLD 215
TV+AA Q D
Sbjct: 292 TVKAAGLQSD 301
>UniRef50_UPI000065DF90 Cluster: methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2-like; n=1; Takifugu
rubripes|Rep: methylenetetrahydrofolate dehydrogenase
(NADP+ dependent) 2-like - Takifugu rubripes
Length = 400
Score = 82.2 bits (194), Expect = 1e-14
Identities = 42/67 (62%), Positives = 52/67 (77%), Gaps = 1/67 (1%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQ-RLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+K GA VID GIN I+DP K+G+ RLVGDV + + A+ +TPVPGGVGPMTV+MLM+
Sbjct: 335 VKEGAAVIDVGINRIQDP--KTGKVRLVGDVDFDGVKEKAAFITPVPGGVGPMTVSMLMK 392
Query: 183 NTVQAAR 203
NTV AAR
Sbjct: 393 NTVAAAR 399
>UniRef50_Q7MVE9 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=52; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 296
Score = 82.2 bits (194), Expect = 1e-14
Identities = 36/66 (54%), Positives = 46/66 (69%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGAVV+D G + D T+KSG RL GDV + E S +TPVPGGVGPMT+ LM N
Sbjct: 227 VKPGAVVVDVGTTLVPDSTRKSGFRLTGDVKFDEVAPKCSYITPVPGGVGPMTIVSLMSN 286
Query: 186 TVQAAR 203
T+ A++
Sbjct: 287 TLLASK 292
>UniRef50_Q8DMU0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=90; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Synechococcus elongatus (Thermosynechococcus
elongatus)
Length = 306
Score = 81.0 bits (191), Expect = 3e-14
Identities = 42/62 (67%), Positives = 47/62 (75%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
I+PGAVVID GIN I+ P KS L GDV Y+ A VAS +TPVPGGVGPMTVAML+ N
Sbjct: 224 IRPGAVVIDVGINRIQRPDGKSS--LWGDVDYEAARAVASYITPVPGGVGPMTVAMLLHN 281
Query: 186 TV 191
TV
Sbjct: 282 TV 283
>UniRef50_Q81RE1 Cluster: Formate--tetrahydrofolate ligase; n=48;
root|Rep: Formate--tetrahydrofolate ligase - Bacillus
anthracis
Length = 562
Score = 80.6 bits (190), Expect = 4e-14
Identities = 39/95 (41%), Positives = 56/95 (58%)
Frame = +2
Query: 254 LTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTG 433
+T T SDI IA+ K I E+AA++ + E+ YG K K+SL + RL+N++ G
Sbjct: 1 MTTTTTVKSDIEIAQEANMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQNEKDG 60
Query: 434 KYIVVAGITPTPLGEGKSTTLIGLVKR*QHIAGRT 538
K ++V I PTP GEGKST +GL + I +T
Sbjct: 61 KVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKT 95
Score = 74.1 bits (174), Expect = 3e-12
Identities = 32/57 (56%), Positives = 39/57 (68%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
GK +R+PS GPT G+K +SQV+PME+ NLH TGDIHA+T ANN LAA
Sbjct: 92 GKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAA 148
>UniRef50_A5V1H2 Cluster: Methylenetetrahydrofolate dehydrogenase
(NADP(+)); n=5; Chloroflexi (class)|Rep:
Methylenetetrahydrofolate dehydrogenase (NADP(+)) -
Roseiflexus sp. RS-1
Length = 288
Score = 80.2 bits (189), Expect = 5e-14
Identities = 38/69 (55%), Positives = 51/69 (73%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGAVV+D G+N +ED R+VGDV + V VASA+TPVPGG GP+T ML+RN
Sbjct: 221 VKPGAVVVDFGVNVLEDG------RVVGDVDFDSVVNVASAITPVPGGTGPVTNVMLLRN 274
Query: 186 TVQAARRQL 212
++AA++QL
Sbjct: 275 VLRAAQQQL 283
>UniRef50_Q87HX2 Cluster: Formate--tetrahydrofolate ligase; n=65;
Bacteria|Rep: Formate--tetrahydrofolate ligase - Vibrio
parahaemolyticus
Length = 582
Score = 80.2 bits (189), Expect = 5e-14
Identities = 35/56 (62%), Positives = 42/56 (75%)
Frame = +1
Query: 532 KNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
++ AC+RQPS GP FG+K YSQV PMEE NLH+TGDIHAVTAA+NL +A
Sbjct: 87 QSVMACIRQPSMGPVFGIKGGAAGGGYSQVAPMEELNLHLTGDIHAVTAAHNLASA 142
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/78 (44%), Positives = 47/78 (60%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGI 457
SDI I R+ I +A + GL P E +G+ KAK+ L RL + + GK ++V I
Sbjct: 3 SDIEICRNTPLSSIDVIAEKAGLLPEEFDTHGKYKAKVHPKCLARLNDNQNGKLVLVTAI 62
Query: 458 TPTPLGEGKSTTLIGLVK 511
TPTPLGEGK+ T IGL +
Sbjct: 63 TPTPLGEGKTVTTIGLAQ 80
>UniRef50_Q5PBL6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Alphaproteobacteria|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Anaplasma marginale (strain St. Maries)
Length = 299
Score = 80.2 bits (189), Expect = 5e-14
Identities = 38/69 (55%), Positives = 49/69 (71%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA+V+D GIN +E+ KK R VGDV ++ V +VTPVPGGVGPMT+A L+
Sbjct: 220 WIKPGAIVVDVGINLVEESGKK---RFVGDVEFEGLQDVPCSVTPVPGGVGPMTIAFLLV 276
Query: 183 NTVQAARRQ 209
NTV + +Q
Sbjct: 277 NTVLGSCKQ 285
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 79.8 bits (188), Expect = 6e-14
Identities = 41/66 (62%), Positives = 48/66 (72%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IKPGA VID GI+ I+ T + RLVGDV Y+ VA +TPVPGGVGPMTVAMLM+N
Sbjct: 256 IKPGACVIDVGISRIK--TSEGKYRLVGDVNYESVKTVAGHITPVPGGVGPMTVAMLMKN 313
Query: 186 TVQAAR 203
T+ A R
Sbjct: 314 TLFAIR 319
>UniRef50_Q16F77 Cluster: Methylenetetrahydrofolate dehydrogenase;
n=4; cellular organisms|Rep: Methylenetetrahydrofolate
dehydrogenase - Aedes aegypti (Yellowfever mosquito)
Length = 337
Score = 79.8 bits (188), Expect = 6e-14
Identities = 38/66 (57%), Positives = 48/66 (72%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GA +ID GI ++DP + +LVGDV + E KVA +TPVPGGVGPMTVAMLM+N
Sbjct: 262 VKEGAAIIDVGITRVKDP-ETGKNKLVGDVDFDEVRKVAGHITPVPGGVGPMTVAMLMKN 320
Query: 186 TVQAAR 203
T AA+
Sbjct: 321 TFIAAK 326
>UniRef50_Q6F9E6 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; Proteobacteria|Rep: Bifunctional protein folD 1
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Acinetobacter sp. (strain ADP1)
Length = 297
Score = 79.8 bits (188), Expect = 6e-14
Identities = 40/69 (57%), Positives = 51/69 (73%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++K AVVID GIN I K RLVGDV +++A+ + SA+TPVPGGVGPMT+A LM+
Sbjct: 228 YLKADAVVIDVGINRIMTHEKT---RLVGDVDFEDALPMVSAITPVPGGVGPMTIAYLMK 284
Query: 183 NTVQAARRQ 209
NT+QA R Q
Sbjct: 285 NTLQAVRLQ 293
>UniRef50_UPI00006CCCC6 Cluster: methylenetetrahydrofolate
dehydrogenase; n=1; Tetrahymena thermophila SB210|Rep:
methylenetetrahydrofolate dehydrogenase - Tetrahymena
thermophila SB210
Length = 342
Score = 79.4 bits (187), Expect = 8e-14
Identities = 44/78 (56%), Positives = 56/78 (71%), Gaps = 4/78 (5%)
Frame = +3
Query: 3 WIKPGAVVIDCGIN-AIE--DPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAM 173
WIK GA+V+D G+N I DPTK +VGDV ++EA K AS +TPVPGG+GPMTV+M
Sbjct: 234 WIKKGAIVLDVGVNKGIPGIDPTK-----VVGDVEFEEAKKRASLITPVPGGIGPMTVSM 288
Query: 174 LMRNTVQA-ARRQLDRLL 224
LM NTVQ +R++ LL
Sbjct: 289 LMYNTVQIWKQRRMQELL 306
>UniRef50_P13995 Cluster: Bifunctional methylenetetrahydrofolate
dehydrogenase/cyclohydrolase, mitochondrial precursor
[Includes: NAD-dependent methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)]; n=66; cellular
organisms|Rep: Bifunctional methylenetetrahydrofolate
dehydrogenase/cyclohydrolase, mitochondrial precursor
[Includes: NAD-dependent methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Homo sapiens (Human)
Length = 350
Score = 79.4 bits (187), Expect = 8e-14
Identities = 39/69 (56%), Positives = 49/69 (71%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK GA VID GIN + DP +LVGDV ++ + A +TPVPGGVGPMTVAMLM+N
Sbjct: 265 IKEGAAVIDVGINRVHDPVTAK-PKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKN 323
Query: 186 TVQAARRQL 212
T+ AA++ L
Sbjct: 324 TIIAAKKVL 332
>UniRef50_A1AL91 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=9; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Pelobacter propionicus (strain DSM 2379)
Length = 283
Score = 79.4 bits (187), Expect = 8e-14
Identities = 38/68 (55%), Positives = 52/68 (76%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIK GAVVID GIN + + ++LVGDV + A + ASA+TPVPGGVGPMT+ ML++
Sbjct: 218 WIKEGAVVIDVGINRVGE------KKLVGDVEFAGASQRASAITPVPGGVGPMTITMLLQ 271
Query: 183 NTVQAARR 206
NT+++A+R
Sbjct: 272 NTLESAKR 279
>UniRef50_Q6ABS5 Cluster: Formate--tetrahydrofolate ligase; n=52;
root|Rep: Formate--tetrahydrofolate ligase -
Propionibacterium acnes
Length = 563
Score = 79.0 bits (186), Expect = 1e-13
Identities = 34/57 (59%), Positives = 43/57 (75%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
GK++ +RQPS GPTFG+K YSQV+PME+ NLH+TGD HA+ AA+NLLAA
Sbjct: 86 GKHSVLALRQPSMGPTFGIKGGAAGAGYSQVLPMEKLNLHLTGDFHAIGAAHNLLAA 142
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/78 (44%), Positives = 48/78 (61%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGI 457
SD+ IAR I ++AA G+ + YGR AK+ L V+ R+ GKY+VV +
Sbjct: 3 SDLEIAREAHLDPIEKVAARAGIDEKYLEPYGRGVAKVDLDVVTHNRDHSCGKYVVVTAM 62
Query: 458 TPTPLGEGKSTTLIGLVK 511
TPTPLGEGK+TT +GL +
Sbjct: 63 TPTPLGEGKTTTAVGLAQ 80
>UniRef50_Q6ALZ5 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=27; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Desulfotalea psychrophila
Length = 296
Score = 78.6 bits (185), Expect = 1e-13
Identities = 34/66 (51%), Positives = 47/66 (71%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA VID G+N + ++ L GDV ++ ++A +TPVPGGVGPMT+AMLM+
Sbjct: 226 WIKPGATVIDVGVNRVGTNSETGKAILRGDVDFEAVKEIAGKITPVPGGVGPMTIAMLMK 285
Query: 183 NTVQAA 200
NT+ +A
Sbjct: 286 NTLASA 291
>UniRef50_A1SQH3 Cluster: Formate--tetrahydrofolate ligase; n=38;
cellular organisms|Rep: Formate--tetrahydrofolate ligase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 559
Score = 78.2 bits (184), Expect = 2e-13
Identities = 34/57 (59%), Positives = 40/57 (70%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
GK A AC+R+PS GP FG+K YSQV+PM + NLH TGD A+ AANNLLAA
Sbjct: 87 GKRAIACLREPSMGPVFGLKGGAAGGGYSQVVPMTDINLHFTGDFAAIAAANNLLAA 143
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/77 (40%), Positives = 49/77 (63%), Gaps = 1/77 (1%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAE-IGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAG 454
SDI IA + + I E+A E +G+ + YG KAK+ ++ L+ L ++ G+ I+V
Sbjct: 3 SDIEIAGAATLRPITEVATESLGIGAEHLVPYGHYKAKVGITYLNSLADRPLGRLILVTA 62
Query: 455 ITPTPLGEGKSTTLIGL 505
++PTP GEGK+TT +GL
Sbjct: 63 LSPTPPGEGKTTTSVGL 79
>UniRef50_UPI000038C811 Cluster: COG0190:
5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl
tetrahydrofolate cyclohydrolase; n=1; Nostoc punctiforme
PCC 73102|Rep: COG0190: 5,10-methylene-tetrahydrofolate
dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase -
Nostoc punctiforme PCC 73102
Length = 292
Score = 77.8 bits (183), Expect = 3e-13
Identities = 36/67 (53%), Positives = 49/67 (73%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGAVV+D G+N + D + KS RL+GDV ++ VA +TPVPGGVGPMTVA+L++N
Sbjct: 224 VKPGAVVVDVGMNRVTDASGKS--RLIGDVDFESTAGVAGFITPVPGGVGPMTVAILLQN 281
Query: 186 TVQAARR 206
T + R
Sbjct: 282 TFTSYSR 288
>UniRef50_O83714 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Treponema pallidum
Length = 315
Score = 77.4 bits (182), Expect = 3e-13
Identities = 35/66 (53%), Positives = 46/66 (69%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+++ GAVVID GI+ + D T G+RL GDV + A+TPVPGGVGPMT+AML+
Sbjct: 222 FVRTGAVVIDVGIHHVPDATAPRGRRLCGDVDFDAVAHKVQAITPVPGGVGPMTIAMLLH 281
Query: 183 NTVQAA 200
NT+ AA
Sbjct: 282 NTLCAA 287
>UniRef50_Q6D2E6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=13; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 287
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/71 (53%), Positives = 52/71 (73%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGA+V+D GIN +E SG ++VGD+ ++ A + AS ++PVPGGVGPMTVA L++
Sbjct: 220 WIKPGAIVLDVGINRLE-----SG-KVVGDIEFETAQERASYISPVPGGVGPMTVATLIQ 273
Query: 183 NTVQAARRQLD 215
NT+QA D
Sbjct: 274 NTLQACEEYHD 284
>UniRef50_Q4FNW1 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=4; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Pelagibacter ubique
Length = 281
Score = 76.6 bits (180), Expect = 6e-13
Identities = 36/68 (52%), Positives = 49/68 (72%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
W+K A+VID GIN E+ +VGDVA++E KVA A+TPVPGGVGPMT+A L++
Sbjct: 218 WVKKDAIVIDVGINKTENG-------IVGDVAFEEVSKVARALTPVPGGVGPMTIACLLK 270
Query: 183 NTVQAARR 206
NT++ +R
Sbjct: 271 NTIECFKR 278
>UniRef50_Q9HPY4 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=8; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Halobacterium salinarium (Halobacterium
halobium)
Length = 297
Score = 76.2 bits (179), Expect = 8e-13
Identities = 39/63 (61%), Positives = 45/63 (71%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAA 200
VVID GIN ++ T+K G LVGDV Y A ASA+TPVPGGVGPMT AML+ NT+ AA
Sbjct: 228 VVIDVGINRVDADTEK-GYELVGDVDYDSAEAAASAITPVPGGVGPMTRAMLLYNTLAAA 286
Query: 201 RRQ 209
Q
Sbjct: 287 SEQ 289
>UniRef50_UPI0000DB7ABF Cluster: PREDICTED: similar to Bifunctional
methylenetetrahydrofolate dehydrogenase/cyclohydrolase,
mitochondrial precursor; n=1; Apis mellifera|Rep:
PREDICTED: similar to Bifunctional
methylenetetrahydrofolate dehydrogenase/cyclohydrolase,
mitochondrial precursor - Apis mellifera
Length = 407
Score = 75.8 bits (178), Expect = 1e-12
Identities = 36/70 (51%), Positives = 48/70 (68%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IKPGA +ID GI I+ K ++VGDV ++ +A +TPVPGGVGPMTVAMLM+N
Sbjct: 338 IKPGACIIDVGITRIKMDNK---YKIVGDVDFENVKSIAGYITPVPGGVGPMTVAMLMKN 394
Query: 186 TVQAARRQLD 215
T+ AA + +
Sbjct: 395 TILAANKNYE 404
>UniRef50_A5WI04 Cluster: Formate--tetrahydrofolate ligase; n=5;
root|Rep: Formate--tetrahydrofolate ligase -
Psychrobacter sp. PRwf-1
Length = 569
Score = 75.8 bits (178), Expect = 1e-12
Identities = 32/57 (56%), Positives = 40/57 (70%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
GK +R+PS GP FG+K Y+QV+PME+ NLH TGD+HA+ AANNLLAA
Sbjct: 95 GKRTVVALREPSVGPVFGIKGGAAGGGYAQVLPMEDINLHFTGDLHAIGAANNLLAA 151
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/78 (42%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
Frame = +2
Query: 275 PSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLS-VLDRLRNQRTGKYIVVA 451
PSDI IA++ + I ++A +IGL ++ YG KAKI+ + V D K ++V
Sbjct: 4 PSDITIAQNATLRPIVDIAKKIGLSADKIEPYGYYKAKINPNDVFDMPAKSSNSKLVLVT 63
Query: 452 GITPTPLGEGKSTTLIGL 505
I PTP GEGK+T IGL
Sbjct: 64 AINPTPAGEGKTTVTIGL 81
>UniRef50_Q8Y624 Cluster: Formate--tetrahydrofolate ligase; n=71;
Bacteria|Rep: Formate--tetrahydrofolate ligase -
Listeria monocytogenes
Length = 560
Score = 74.5 bits (175), Expect = 2e-12
Identities = 35/65 (53%), Positives = 44/65 (67%)
Frame = +1
Query: 505 GEALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAAN 684
G+AL+ K A +R+PS GPT G+K Y+QVIPME+ NLH TGD HA+TAAN
Sbjct: 83 GDALSKKDKKTVIA-LREPSLGPTMGIKGGATGGGYAQVIPMEDINLHFTGDFHAITAAN 141
Query: 685 NLLAA 699
N L+A
Sbjct: 142 NALSA 146
Score = 62.9 bits (146), Expect = 8e-09
Identities = 30/76 (39%), Positives = 44/76 (57%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGI 457
SDI IA + + +A +GL + YG+ KAK+S + L+++ GK ++V I
Sbjct: 7 SDIEIASKAEILPVTTIAEHLGLDADALELYGKYKAKLSYDTIHSLKDKEPGKLVLVTAI 66
Query: 458 TPTPLGEGKSTTLIGL 505
PTP GEGKST +GL
Sbjct: 67 NPTPAGEGKSTVTVGL 82
>UniRef50_Q5SJ94 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Thermus thermophilus|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 282
Score = 74.5 bits (175), Expect = 2e-12
Identities = 37/66 (56%), Positives = 49/66 (74%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
W++ GA+V+D G+N +E RL+GDV + E +VA A+TPVPGGVGPMTVAMLM
Sbjct: 216 WVREGAIVVDVGVNRVEG-------RLLGDV-HPEVAEVAFALTPVPGGVGPMTVAMLMG 267
Query: 183 NTVQAA 200
NT++AA
Sbjct: 268 NTLEAA 273
>UniRef50_Q987T6 Cluster: Bifunctional protein folD 2 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; Alphaproteobacteria|Rep: Bifunctional protein folD
2 [Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Rhizobium loti (Mesorhizobium loti)
Length = 306
Score = 74.1 bits (174), Expect = 3e-12
Identities = 39/68 (57%), Positives = 47/68 (69%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGA VID GIN+ P S R+VGDV VAS +TPVPGGVGP+TVA+L+RN
Sbjct: 224 VKPGAAVIDIGINSEIGPDGTS--RIVGDVDTDSVKDVASWITPVPGGVGPITVAILLRN 281
Query: 186 TVQAARRQ 209
T+ A RQ
Sbjct: 282 TMVALSRQ 289
>UniRef50_Q5V5Y2 Cluster: Formate--tetrahydrofolate ligase; n=406;
root|Rep: Formate--tetrahydrofolate ligase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 553
Score = 73.7 bits (173), Expect = 4e-12
Identities = 34/65 (52%), Positives = 45/65 (69%)
Frame = +1
Query: 505 GEALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAAN 684
G+ L H G+ A +R+PS GP FGVK SQV+PME+ NLH TGD+HA+T+A+
Sbjct: 70 GQTLN-HVGEEAMIAIREPSLGPVFGVKGGAAGGGRSQVLPMEDINLHFTGDLHALTSAH 128
Query: 685 NLLAA 699
NL+AA
Sbjct: 129 NLIAA 133
Score = 51.2 bits (117), Expect = 3e-05
Identities = 27/73 (36%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Frame = +2
Query: 317 IGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQ---RTGKYIVVAGITPTPLGEGKS 487
I EL GL ++ +G AK+ ++RLR Q R ++V G+TPTP GEGK+
Sbjct: 4 IWELVEPWGLGLDDLQYFGEYTAKVKQHAIERLREQAENREQNLVLVTGMTPTPKGEGKT 63
Query: 488 TTLIGLVKR*QHI 526
T +GL + H+
Sbjct: 64 VTTVGLGQTLNHV 76
>UniRef50_Q8KN38 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Sphingobium chlorophenolicum|Rep: Bifunctional
protein folD [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Sphingobium
chlorophenolicum
Length = 316
Score = 73.7 bits (173), Expect = 4e-12
Identities = 41/69 (59%), Positives = 48/69 (69%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
W+K GAVVID GIN I +S R+VGDVA E + A+A TPVPGGVGPMT+A L
Sbjct: 219 WVKAGAVVIDVGINRIALDDGRS--RIVGDVASDE-IGHAAAFTPVPGGVGPMTIACLAA 275
Query: 183 NTVQAARRQ 209
VQAARR+
Sbjct: 276 EYVQAARRR 284
>UniRef50_Q54VK0 Cluster: Methenyl tetrahydrofolate cyclohydrolase /
NADP-dependent methylene H4F dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Methenyl
tetrahydrofolate cyclohydrolase / NADP-dependent
methylene H4F dehydrogenase - Dictyostelium discoideum
AX4
Length = 440
Score = 72.5 bits (170), Expect = 1e-11
Identities = 35/65 (53%), Positives = 48/65 (73%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G ++ID GI+ ED TKKSG ++VGD+ EA + A TPVPGGVGP+TVA L+RN
Sbjct: 314 LKRGVILIDVGISFKEDSTKKSGYKMVGDID-PEAYSRSIAYTPVPGGVGPLTVACLLRN 372
Query: 186 TVQAA 200
+++A
Sbjct: 373 VLRSA 377
>UniRef50_Q5FJY2 Cluster: Formate--tetrahydrofolate ligase 1; n=56;
Bacteria|Rep: Formate--tetrahydrofolate ligase 1 -
Lactobacillus acidophilus
Length = 558
Score = 72.5 bits (170), Expect = 1e-11
Identities = 37/77 (48%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLR-NQRTGKYIVVAG 454
SDI IA+ K I E+AA++ L ++ YG+ KAKI+ ++R+R N + GK I+V
Sbjct: 3 SDIEIAQETKELPIEEIAAKVNLKKEDLEPYGQDKAKINWKAINRIRKNDKLGKLILVTS 62
Query: 455 ITPTPLGEGKSTTLIGL 505
I+PTP GEGKST IGL
Sbjct: 63 ISPTPAGEGKSTITIGL 79
Score = 68.9 bits (161), Expect = 1e-10
Identities = 31/65 (47%), Positives = 42/65 (64%)
Frame = +1
Query: 505 GEALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAAN 684
G+A+ KN +R+PS GP FG+K +Q+IPME+ NLH TGD+HA+TAA
Sbjct: 80 GDAIHNQLHKNTLIALREPSMGPVFGLKGGATGGGRAQIIPMEDINLHFTGDMHALTAAI 139
Query: 685 NLLAA 699
+ LAA
Sbjct: 140 DTLAA 144
>UniRef50_Q2B9L0 Cluster: Bifunctional protein FolD; n=1; Bacillus
sp. NRRL B-14911|Rep: Bifunctional protein FolD -
Bacillus sp. NRRL B-14911
Length = 322
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/70 (50%), Positives = 48/70 (68%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIKPGAV++D G N G VGD Y ++ ASA+TPVPGGVGP+T++ML++
Sbjct: 259 WIKPGAVILDAGYN--------KGN--VGDAEYDSCLEKASAITPVPGGVGPVTISMLLK 308
Query: 183 NTVQAARRQL 212
+TV+AA + L
Sbjct: 309 HTVEAAEKTL 318
>UniRef50_Q9KQQ6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=44; Gammaproteobacteria|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Vibrio cholerae
Length = 286
Score = 71.7 bits (168), Expect = 2e-11
Identities = 38/68 (55%), Positives = 47/68 (69%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIK GAVV+D GIN ++ +G +LVGDV Y A AS +TPVPGGVGPMTVA L+
Sbjct: 220 WIKEGAVVVDVGINRLD-----TG-KLVGDVEYDVARTRASFITPVPGGVGPMTVASLIE 273
Query: 183 NTVQAARR 206
NT+ A +
Sbjct: 274 NTMMACEQ 281
>UniRef50_Q057D7 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Enterobacteriaceae|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Buchnera aphidicola subsp. Cinara cedri
Length = 284
Score = 69.7 bits (163), Expect = 7e-11
Identities = 34/65 (52%), Positives = 44/65 (67%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIK GA+VID GIN + + K ++VGDV ++ S +TPVPGGVGPMTV L+
Sbjct: 220 WIKLGAIVIDIGINYLYNKNK---YKIVGDVHFKSTSVKTSYITPVPGGVGPMTVVSLLE 276
Query: 183 NTVQA 197
NT+QA
Sbjct: 277 NTLQA 281
>UniRef50_A6NP56 Cluster: Uncharacterized protein ENSP00000372121;
n=5; Eutheria|Rep: Uncharacterized protein
ENSP00000372121 - Homo sapiens (Human)
Length = 200
Score = 69.3 bits (162), Expect = 9e-11
Identities = 34/62 (54%), Positives = 42/62 (67%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK A V D GIN + DP +LVGDV ++ + A +TPVPGGVGPMTVAMLM+N
Sbjct: 140 IKEEAAVTDMGINRVHDPVTAK-LKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKN 198
Query: 186 TV 191
T+
Sbjct: 199 TI 200
>UniRef50_Q4FTX6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=24; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Psychrobacter arcticum
Length = 295
Score = 69.3 bits (162), Expect = 9e-11
Identities = 37/68 (54%), Positives = 43/68 (63%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIK GAVVID G + PT G VGD+ Q +ASA TPVPGGVGPMT+ L+R
Sbjct: 231 WIKAGAVVIDAGFH----PTDNGG---VGDIELQGVENIASAYTPVPGGVGPMTINTLIR 283
Query: 183 NTVQAARR 206
TV AA +
Sbjct: 284 QTVDAAEK 291
>UniRef50_A6CAY4 Cluster: Formate--tetrahydrofolate ligase; n=3;
root|Rep: Formate--tetrahydrofolate ligase -
Planctomyces maris DSM 8797
Length = 565
Score = 68.9 bits (161), Expect = 1e-10
Identities = 33/65 (50%), Positives = 42/65 (64%)
Frame = +2
Query: 311 KDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKST 490
+DI LA EIGL P + YGR KAK+ + D+ ++ KYI V I PTPLGEGK+
Sbjct: 15 RDIDSLAKEIGLGPGDYEPYGRLKAKLVHGLADKYADRPLAKYIGVTAINPTPLGEGKTV 74
Query: 491 TLIGL 505
T+IGL
Sbjct: 75 TVIGL 79
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
G +R+PS P FG+K + P + NLH TGD+HAVT+A NLLA+
Sbjct: 87 GHTTIGTLREPSLAPVFGIKGGGAGGGNCTLEPQSDINLHFTGDLHAVTSATNLLAS 143
>UniRef50_A7DNA7 Cluster: Methylenetetrahydrofolate dehydrogenase
(NADP(+)); n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Methylenetetrahydrofolate dehydrogenase
(NADP(+)) - Candidatus Nitrosopumilus maritimus SCM1
Length = 287
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/65 (52%), Positives = 46/65 (70%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK GA+VID I+ ++ +LVGD Y++ ++ AS TPVPGGVGPMTVAML++N
Sbjct: 222 IKEGAIVIDVAISRFQE-------KLVGDADYEDIIQKASFATPVPGGVGPMTVAMLLKN 274
Query: 186 TVQAA 200
T+ AA
Sbjct: 275 TITAA 279
>UniRef50_Q3ZX40 Cluster: Formate--tetrahydrofolate ligase; n=12;
cellular organisms|Rep: Formate--tetrahydrofolate ligase
- Dehalococcoides sp. (strain CBDB1)
Length = 597
Score = 68.5 bits (160), Expect = 2e-10
Identities = 35/68 (51%), Positives = 47/68 (69%), Gaps = 1/68 (1%)
Frame = +2
Query: 311 KDIGELAAEIGLCPSEVSQYGRTKAKISLS-VLDRLRNQRTGKYIVVAGITPTPLGEGKS 487
K + LA E+GL E+ +G+ AK+ + VL RL+++ GKYI V ITPTPLGEGKS
Sbjct: 32 KPVKVLAMELGLTEDEIIPHGKYIAKVDFAGVLARLKDRPNGKYIDVTAITPTPLGEGKS 91
Query: 488 TTLIGLVK 511
TT +GLV+
Sbjct: 92 TTTMGLVQ 99
Score = 55.2 bits (127), Expect = 2e-06
Identities = 25/54 (46%), Positives = 33/54 (61%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNL 690
GK +RQPS GPTF +K SQ +P+ F+L +TGDI AVT ++NL
Sbjct: 105 GKKVTGAIRQPSSGPTFNIKGSAAGGGLSQCLPLSPFSLGLTGDIDAVTNSHNL 158
>UniRef50_UPI00005A5066 Cluster: PREDICTED: similar to Bifunctional
methylenetetrahydrofolate dehydrogenase/cyclohydrolase,
mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Bifunctional
methylenetetrahydrofolate dehydrogenase/cyclohydrolase,
mitochondrial precursor - Canis familiaris
Length = 239
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/69 (53%), Positives = 50/69 (72%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK GA +I+ GIN ++DP S +LVGDV ++ K A+ +TPV GVGPMTVAMLM+N
Sbjct: 133 IKEGAALINVGINRVQDPIL-SKAKLVGDVDFEGIRKNANYITPV-WGVGPMTVAMLMKN 190
Query: 186 TVQAARRQL 212
T+ AA++ L
Sbjct: 191 TIIAAKKVL 199
>UniRef50_Q8EQ43 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=45; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Oceanobacillus iheyensis
Length = 285
Score = 68.1 bits (159), Expect = 2e-10
Identities = 34/67 (50%), Positives = 47/67 (70%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+IK AVVID GIN +K +L GDV ++ A + AS +TPVP GVGPMT+ ML++
Sbjct: 218 YIKEDAVVIDVGIN------RKDDGKLTGDVDFESAEQKASYITPVPRGVGPMTITMLLK 271
Query: 183 NTVQAAR 203
NT++AA+
Sbjct: 272 NTIKAAK 278
>UniRef50_Q7TU81 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; Prochlorococcus marinus|Rep: Bifunctional protein
folD [Includes: Methylenetetrahydrofolate dehydrogenase
(EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase
(EC 3.5.4.9)] - Prochlorococcus marinus subsp. pastoris
(strain CCMP 1378 / MED4)
Length = 298
Score = 67.7 bits (158), Expect = 3e-10
Identities = 33/69 (47%), Positives = 47/69 (68%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++K GAV+ID GI+ + + KS RL GDV ++ + A TPVPGGVGPMTV ML+
Sbjct: 219 FVKEGAVIIDVGIHRLTS-SDKSKTRLCGDVLLEDVIPKVFAYTPVPGGVGPMTVTMLLV 277
Query: 183 NTVQAARRQ 209
NT+ + ++Q
Sbjct: 278 NTIFSWQKQ 286
>UniRef50_Q1II76 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Acidobacteria|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Acidobacteria bacterium (strain Ellin345)
Length = 307
Score = 67.7 bits (158), Expect = 3e-10
Identities = 39/83 (46%), Positives = 51/83 (61%), Gaps = 16/83 (19%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTK----------------KSGQRLVGDVAYQEAVKVASAVT 134
++KPGA V+D GIN I D + K+G LVGD + + +VA A T
Sbjct: 219 FVKPGATVLDVGINKITDRAEFEKFFAGDAKREAAFAKNGSTLVGD-CHPKVAEVAGAFT 277
Query: 135 PVPGGVGPMTVAMLMRNTVQAAR 203
PVPGGVGP+T+AMLM NTV+AA+
Sbjct: 278 PVPGGVGPLTIAMLMANTVKAAK 300
>UniRef50_Q1AVQ0 Cluster: Bifunctional protein folD 2 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Rubrobacter xylanophilus DSM 9941|Rep: Bifunctional
protein folD 2 [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 320
Score = 67.7 bits (158), Expect = 3e-10
Identities = 29/67 (43%), Positives = 42/67 (62%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+++ G + +D GIN + DP LVGD+ + + A A+TPVPGGVGP+T L++
Sbjct: 230 YVREGVIAVDVGINPVADPGGSGRTLLVGDLDFGSVARKAEALTPVPGGVGPITDVWLLK 289
Query: 183 NTVQAAR 203
NTV A R
Sbjct: 290 NTVAAGR 296
>UniRef50_Q74J95 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Lactobacillus|Rep: Bifunctional protein folD 1
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Lactobacillus johnsonii
Length = 283
Score = 67.7 bits (158), Expect = 3e-10
Identities = 34/65 (52%), Positives = 43/65 (66%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGA VID GIN + + LVGDV + + +VA +TPVPGGVGPMT+A LM+
Sbjct: 221 VKPGATVIDVGIN------RMANHYLVGDVDFDDVKEVAKNITPVPGGVGPMTIATLMQQ 274
Query: 186 TVQAA 200
TV A
Sbjct: 275 TVDLA 279
>UniRef50_Q1DFW5 Cluster: Formate--tetrahydrofolate ligase; n=2;
Bacteria|Rep: Formate--tetrahydrofolate ligase -
Myxococcus xanthus (strain DK 1622)
Length = 551
Score = 67.3 bits (157), Expect = 4e-10
Identities = 29/58 (50%), Positives = 39/58 (67%)
Frame = +1
Query: 526 RGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
RG+ A A +R+PS GP FGVK + + P + NLH TGD+HA+T+ANNLL+A
Sbjct: 74 RGRRAVAALREPSLGPVFGVKGGGTGGGQASLEPAADINLHFTGDLHAITSANNLLSA 131
Score = 56.0 bits (129), Expect = 9e-07
Identities = 26/61 (42%), Positives = 40/61 (65%)
Frame = +2
Query: 323 ELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKSTTLIG 502
++ AE+GL P +V +G +AK+SL L + R R G+ ++V+ I PTP GEGK+T +
Sbjct: 8 DVGAELGLSPEDVLPWGTHRAKVSLDALGK-RGGRQGRLVLVSAINPTPPGEGKTTMSVA 66
Query: 503 L 505
L
Sbjct: 67 L 67
>UniRef50_Q63SL6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=226; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 285
Score = 67.3 bits (157), Expect = 4e-10
Identities = 33/67 (49%), Positives = 45/67 (67%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGA VID G+N ++ +L GDV + +VA +TPVPGGVGPMT+ ML+ N
Sbjct: 220 VKPGATVIDVGMNRNDEG------KLCGDVDFAGVSQVAGHITPVPGGVGPMTITMLLVN 273
Query: 186 TVQAARR 206
T++AA R
Sbjct: 274 TIEAAER 280
>UniRef50_Q83FS2 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Tropheryma whipplei|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 295
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/78 (47%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQR-LVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLM 179
WIKPGAVV+D GIN + SG+ L GDV + +AS ++PV GGVGPMT AMLM
Sbjct: 221 WIKPGAVVVDVGIN--QSGVSSSGKMILTGDV-HPLTKNIASYISPVVGGVGPMTRAMLM 277
Query: 180 RNTVQAARRQLDRLLAPS 233
N + + R + L S
Sbjct: 278 SNVINLSERDFRKRLYAS 295
>UniRef50_O84081 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=7; Chlamydiaceae|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Chlamydia trachomatis
Length = 287
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/62 (54%), Positives = 41/62 (66%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAA 200
V++D G + I K G LVGDV + V V A+TPVPGGVGPMTVAMLMRNT ++
Sbjct: 224 VIMDVGTSRIPAANPK-GYILVGDVDFNNVVPVCRAITPVPGGVGPMTVAMLMRNTWESF 282
Query: 201 RR 206
R
Sbjct: 283 LR 284
>UniRef50_P56467 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=7; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Helicobacter pylori (Campylobacter pylori)
Length = 290
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/68 (48%), Positives = 43/68 (63%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GAVV+D GIN + D R+VGDV + KVA +TPVP GVGPMT+ L+ N
Sbjct: 224 LKKGAVVVDIGINHLNDG------RIVGDVDFNNVQKVAGFITPVPKGVGPMTIVSLLEN 277
Query: 186 TVQAARRQ 209
T+ A +Q
Sbjct: 278 TLIAFEKQ 285
>UniRef50_Q4DH06 Cluster: Methylenetetrahydrofolate
dehydrogenase-like protein, putative; n=1; Trypanosoma
cruzi|Rep: Methylenetetrahydrofolate dehydrogenase-like
protein, putative - Trypanosoma cruzi
Length = 375
Score = 64.5 bits (150), Expect = 3e-09
Identities = 32/68 (47%), Positives = 45/68 (66%), Gaps = 3/68 (4%)
Frame = +3
Query: 3 WIKPGAVVIDCGIN---AIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAM 173
++KPGA+V+D IN A +R+ GDV + A+AVTPVPGG+GP+TVA
Sbjct: 258 FVKPGAIVLDVAINEDCASGGEMTSGSRRVCGDVDLASVREKAAAVTPVPGGIGPLTVAY 317
Query: 174 LMRNTVQA 197
LM+NT++A
Sbjct: 318 LMQNTLKA 325
>UniRef50_A0DMT9 Cluster: Chromosome undetermined scaffold_57, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_57,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 309
Score = 64.5 bits (150), Expect = 3e-09
Identities = 32/61 (52%), Positives = 41/61 (67%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
WIK GA VID GI I + +VGD+ +Q+A+ S +TPVPGGVGP+TV+ML R
Sbjct: 224 WIKNGAKVIDVGITRIPGTNQ-----IVGDIEFQKALPRVSFITPVPGGVGPLTVSMLFR 278
Query: 183 N 185
N
Sbjct: 279 N 279
>UniRef50_A0JTZ0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=51; Actinobacteria (class)|Rep: Bifunctional protein
folD [Includes: Methylenetetrahydrofolate dehydrogenase
(EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase
(EC 3.5.4.9)] - Arthrobacter sp. (strain FB24)
Length = 302
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/70 (50%), Positives = 48/70 (68%), Gaps = 1/70 (1%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDP-TKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+KPGA ++D G+ DP T KS ++ GD+ A +VA ++P PGGVGPMTVA+LM
Sbjct: 228 VKPGAALLDVGVTRETDPETGKS--KVHGDID-PAAAEVAGWISPNPGGVGPMTVALLMT 284
Query: 183 NTVQAARRQL 212
N V+AA R+L
Sbjct: 285 NVVEAAERKL 294
>UniRef50_Q8TK95 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Methanosarcina acetivorans
Length = 290
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/69 (46%), Positives = 43/69 (62%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G V+ D GI ED + GDV ++ +K AS VTPVPGGVGPMT+AMLM++
Sbjct: 229 VKEGTVIFDAGITKEEDG-------VYGDVDFENVIKKASLVTPVPGGVGPMTIAMLMKH 281
Query: 186 TVQAARRQL 212
+ A + L
Sbjct: 282 VLLCAEKSL 290
>UniRef50_A0C3Q0 Cluster: Chromosome undetermined scaffold_147,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_147,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 404
Score = 63.3 bits (147), Expect = 6e-09
Identities = 34/60 (56%), Positives = 41/60 (68%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GA+VID GI+ E K G ++VGDV + AS +TPVPGGVGPMTV MLMRN
Sbjct: 324 VKQGAIVIDVGISQGE----KKG-KIVGDVDFDVVKNQASLITPVPGGVGPMTVCMLMRN 378
>UniRef50_Q9PQS1 Cluster: Formate--tetrahydrofolate ligase; n=1;
Ureaplasma parvum|Rep: Formate--tetrahydrofolate ligase
- Ureaplasma parvum (Ureaplasma urealyticum biotype 1)
Length = 521
Score = 63.3 bits (147), Expect = 6e-09
Identities = 29/64 (45%), Positives = 39/64 (60%)
Frame = +1
Query: 508 EALTAHRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANN 687
+AL H G A +R+PS GP FG+K S + P ++ NLH +GD HA+TAANN
Sbjct: 66 DALNKH-GYKAIGALREPSMGPVFGMKGTGSGGGLSFLKPFDKINLHFSGDFHAITAANN 124
Query: 688 LLAA 699
L+ A
Sbjct: 125 LIVA 128
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/66 (40%), Positives = 37/66 (56%)
Frame = +2
Query: 311 KDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKST 490
K I E+ + GL + YG AKI + +L N++ K IV+ + P P GEGK+T
Sbjct: 3 KIIEEMINKKGLLIDDYELYGNEIAKIKS--IKKL-NKKDSKLIVITSMNPNPAGEGKTT 59
Query: 491 TLIGLV 508
T IGLV
Sbjct: 60 TAIGLV 65
>UniRef50_Q5FJG5 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=7; Firmicutes|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Lactobacillus acidophilus
Length = 283
Score = 63.3 bits (147), Expect = 6e-09
Identities = 33/71 (46%), Positives = 43/71 (60%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G VV+D G+N + +LVGDV ++ K AS +TPVPGGVGP+TV LM
Sbjct: 219 VKDGVVVVDVGMNHVNG-------KLVGDVDFENVKKKASYITPVPGGVGPLTVQFLMEA 271
Query: 186 TVQAARRQLDR 218
V+ RRQ R
Sbjct: 272 VVKLTRRQNGR 282
>UniRef50_Q3AYX2 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=36; cellular organisms|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Synechococcus sp. (strain CC9902)
Length = 293
Score = 62.5 bits (145), Expect = 1e-08
Identities = 34/64 (53%), Positives = 42/64 (65%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IKPGA V+D GI+ +K L GDV E +A+A++PVPGGVGPMTV ML+ N
Sbjct: 220 IKPGAAVVDVGIH------RKPEGGLCGDVRAAEVEPIAAALSPVPGGVGPMTVTMLLVN 273
Query: 186 TVQA 197
TV A
Sbjct: 274 TVVA 277
>UniRef50_Q6MI74 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Bdellovibrio bacteriovorus|Rep: Bifunctional
protein folD [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Bdellovibrio
bacteriovorus
Length = 288
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/67 (47%), Positives = 43/67 (64%)
Frame = +3
Query: 9 KPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNT 188
K A+VID G++ G +L GDV ++E A A TPVPGGVGPMT+AML++NT
Sbjct: 221 KKDAIVIDVGMHG-----SGQGGKLCGDVRFEELDGWAKAATPVPGGVGPMTIAMLLKNT 275
Query: 189 VQAARRQ 209
Q A ++
Sbjct: 276 CQLAEQR 282
>UniRef50_Q2JCX4 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Frankia|Rep: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Frankia sp. (strain CcI3)
Length = 276
Score = 62.5 bits (145), Expect = 1e-08
Identities = 34/67 (50%), Positives = 44/67 (65%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+++PGA VID G E +GQ VGDV VA A+TPVPGGVGP+T +L+R
Sbjct: 215 FVRPGAAVIDVGTVVTE-----TGQ--VGDVDAAAVSSVAGALTPVPGGVGPVTTMLLLR 267
Query: 183 NTVQAAR 203
NT++AAR
Sbjct: 268 NTIRAAR 274
>UniRef50_Q9ZD32 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=13; Rickettsia|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Rickettsia prowazekii
Length = 286
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/70 (41%), Positives = 43/70 (61%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
+ P A+VID GIN I S ++ GDV ++ +TPVPGG+GPMT+A L++
Sbjct: 221 YFNPEAIVIDVGINRI------SHNKIAGDVDFENVKSKVKYITPVPGGIGPMTIAFLLK 274
Query: 183 NTVQAARRQL 212
NTV+A + +
Sbjct: 275 NTVKAFKNAI 284
>UniRef50_Q24UZ7 Cluster: Bifunctional protein folD 2 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=4; Peptococcaceae|Rep: Bifunctional protein folD 2
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Desulfitobacterium hafniense (strain Y51)
Length = 284
Score = 61.3 bits (142), Expect = 2e-08
Identities = 29/68 (42%), Positives = 44/68 (64%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+KPGA+V+D GIN I + GDV ++E +VAS ++PVPGGVG +T A++M+N
Sbjct: 219 VKPGAIVVDAGINEIPGG-------ICGDVDFEEVKEVASLISPVPGGVGSLTTALIMKN 271
Query: 186 TVQAARRQ 209
++ Q
Sbjct: 272 VLKGITLQ 279
>UniRef50_Q74GN1 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=13; Bacteria|Rep: Bifunctional protein folD 1
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Geobacter sulfurreducens
Length = 290
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/64 (51%), Positives = 43/64 (67%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G V+ID GIN +E SG ++VGDV ++ + S +TPVPGGVG MTVA LM N
Sbjct: 225 VKDGVVLIDVGINRLE-----SG-KIVGDVDFENVAQKCSWITPVPGGVGRMTVAALMIN 278
Query: 186 TVQA 197
T+ A
Sbjct: 279 TLMA 282
>UniRef50_A3EUA4 Cluster: Formyltetrahydrofolate synthetase; n=2;
Bacteria|Rep: Formyltetrahydrofolate synthetase -
Leptospirillum sp. Group II UBA
Length = 557
Score = 60.5 bits (140), Expect = 4e-08
Identities = 27/57 (47%), Positives = 35/57 (61%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
G +RQPS GP FG+K S + P + NLH+TGD+HAV AA+NLLA+
Sbjct: 78 GTRTVVTIRQPSMGPVFGIKGGGAGGGKSTIEPSDVLNLHLTGDVHAVGAAHNLLAS 134
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 317 IGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGK-----YIVVAGITPTPLGEG 481
+ ++A +G+ + +G +AKI L+ G+ Y++V G+TPTPLGEG
Sbjct: 3 LDKMAQSMGVPETHFHPFGPGRAKIDPRYLETFSPPSFGREPSPLYVLVTGMTPTPLGEG 62
Query: 482 KSTTLIGLVKR*QHIAGRT 538
K+TT IGL + RT
Sbjct: 63 KTTTSIGLSMALNRLGTRT 81
>UniRef50_Q6F1V0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; Mollicutes|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Mesoplasma florum (Acholeplasma florum)
Length = 286
Score = 60.5 bits (140), Expect = 4e-08
Identities = 33/71 (46%), Positives = 44/71 (61%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK AV+ID GI I DP +LVGDV +++ +S +TPVPGGVGPMTV LM N
Sbjct: 219 IKKDAVIIDVGI--IRDPVTN---KLVGDVDFEKVKLKSSYITPVPGGVGPMTVITLMEN 273
Query: 186 TVQAARRQLDR 218
T + +++
Sbjct: 274 TFVLYEKHINK 284
>UniRef50_Q8RDM4 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Fusobacterium nucleatum|Rep: Bifunctional protein
folD [Includes: Methylenetetrahydrofolate dehydrogenase
(EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase
(EC 3.5.4.9)] - Fusobacterium nucleatum subsp. nucleatum
Length = 283
Score = 59.7 bits (138), Expect = 7e-08
Identities = 31/64 (48%), Positives = 42/64 (65%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GAVVID GIN + +L GDV ++ K AS +TPVPGGVG +TVAML+ N
Sbjct: 219 VKEGAVVIDVGINRVNG-------KLEGDVDFENVQKKASHITPVPGGVGALTVAMLLSN 271
Query: 186 TVQA 197
+++
Sbjct: 272 ILKS 275
>UniRef50_Q8RAD0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Thermoanaerobacter|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Thermoanaerobacter tengcongensis
Length = 280
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/64 (45%), Positives = 41/64 (64%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G V+ID GIN E ++ GD ++ AS VTPVPGGVGP+T AM+++N
Sbjct: 216 VKEGVVLIDAGINVHEG-------KIYGDADFESIKDKASYVTPVPGGVGPVTTAMILKN 268
Query: 186 TVQA 197
T++A
Sbjct: 269 TLEA 272
>UniRef50_Q4A6B1 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Mycoplasma synoviae 53|Rep: Bifunctional protein
folD [Includes: Methylenetetrahydrofolate dehydrogenase
(EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase
(EC 3.5.4.9)] - Mycoplasma synoviae (strain 53)
Length = 278
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 1/64 (1%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIE-DPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
IK GA++ID G N + DP+ + GDV ++ ASA+TPVPGGVGP+TV L++
Sbjct: 217 IKQGAIIIDVGTNYDQNDPSV-----IFGDVDHESVKTKASAITPVPGGVGPLTVVCLLK 271
Query: 183 NTVQ 194
N V+
Sbjct: 272 NLVE 275
>UniRef50_A4EAK0 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Collinsella aerofaciens ATCC 25986
Length = 284
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/67 (41%), Positives = 42/67 (62%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
++ G +ID GIN E + +LVGDV + A + A+TPVPGGVG +T A+L ++
Sbjct: 220 VRGGQTIIDVGINWDE-----AAGKLVGDVDFDAAEPIVGAITPVPGGVGAVTTAILAKH 274
Query: 186 TVQAARR 206
++AA R
Sbjct: 275 VIEAAER 281
>UniRef50_Q979W3 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Thermoplasma|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Thermoplasma volcanium
Length = 281
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/69 (39%), Positives = 43/69 (62%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++ +VVID GIN ++D +++GD+ + + + AVTPVPGGVGP+T ++
Sbjct: 213 YVTESSVVIDVGINYVQD-------KVIGDIDFDKVSEKVEAVTPVPGGVGPITATNILS 265
Query: 183 NTVQAARRQ 209
N V+AA Q
Sbjct: 266 NLVKAAEYQ 274
>UniRef50_Q97CL3 Cluster: Formate--tetrahydrofolate ligase; n=4;
Thermoplasmatales|Rep: Formate--tetrahydrofolate ligase
- Thermoplasma volcanium
Length = 536
Score = 56.4 bits (130), Expect = 7e-07
Identities = 29/65 (44%), Positives = 42/65 (64%)
Frame = +2
Query: 311 KDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKST 490
+DI E+ E+GL + YGR AK+SL++ + N++ K I+V +TPT GEGK+T
Sbjct: 2 RDIEEILHEMGLSKDDYELYGRYMAKLSLNLQEV--NKKKAKLILVTAMTPTAAGEGKTT 59
Query: 491 TLIGL 505
T IGL
Sbjct: 60 TTIGL 64
Score = 54.8 bits (126), Expect = 2e-06
Identities = 26/57 (45%), Positives = 35/57 (61%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
GKN +R+PS GP FG+K S+V P + NL TGD A++AA+NLL+A
Sbjct: 72 GKNVAIAIREPSLGPCFGIKGGATGGGKSKVEPSDRINLLFTGDFPAISAAHNLLSA 128
>UniRef50_Q0SFQ8 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=5; Actinomycetales|Rep: Bifunctional protein folD 1
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Rhodococcus sp. (strain RHA1)
Length = 297
Score = 55.6 bits (128), Expect = 1e-06
Identities = 34/68 (50%), Positives = 41/68 (60%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+ GAVVID G A D GQ L+GDV A A+TPVPGGVGP+T A+L+ +
Sbjct: 219 VADGAVVIDVGTTATAD-----GQ-LLGDVDAAAVDGRAGALTPVPGGVGPVTTALLLNH 272
Query: 186 TVQAARRQ 209
TV AA Q
Sbjct: 273 TVDAAGTQ 280
>UniRef50_A1HML1 Cluster: Methenyltetrahydrofolate cyclohydrolase;
n=1; Thermosinus carboxydivorans Nor1|Rep:
Methenyltetrahydrofolate cyclohydrolase - Thermosinus
carboxydivorans Nor1
Length = 279
Score = 55.2 bits (127), Expect = 2e-06
Identities = 27/64 (42%), Positives = 39/64 (60%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
++PGAVVID GIN + +VGDV Y +A A+TPVPGGVG +T M++
Sbjct: 219 VRPGAVVIDVGINEVNGA-------VVGDVDYDAVFPIAGAITPVPGGVGAVTTVMVVEA 271
Query: 186 TVQA 197
+++
Sbjct: 272 ALRS 275
>UniRef50_A5CF58 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Orientia tsutsugamushi Boryong|Rep: Bifunctional
protein folD [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Orientia tsutsugamushi
(strain Boryong) (Rickettsia tsutsugamushi)
Length = 301
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +3
Query: 27 IDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAAR 203
ID GI+ I D + ++LVGD + + + +TPVPGGVGPMTVA L++NT+ AA+
Sbjct: 228 IDVGISHIYD-LQTHKRKLVGDGDFLKIKDLVKFITPVPGGVGPMTVAYLLKNTLTAAK 285
>UniRef50_Q14NV0 Cluster: Probable formate-tetrahydrofolate ligase
protein; n=1; Spiroplasma citri|Rep: Probable
formate-tetrahydrofolate ligase protein - Spiroplasma
citri
Length = 535
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/59 (40%), Positives = 33/59 (55%)
Frame = +1
Query: 523 HRGKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLLAA 699
H G +R+PS GP FG+K + P E NLH TGD HA+T ANN++++
Sbjct: 70 HLGYQTTLALREPSLGPVFGLKGSATGGGECIMEPENEINLHYTGDFHAITTANNMVSS 128
Score = 40.7 bits (91), Expect = 0.036
Identities = 22/73 (30%), Positives = 37/73 (50%)
Frame = +2
Query: 326 LAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKSTTLIGL 505
+ +I L ++ +YG AK+ + + + K+I+V I PT GEGK+T IG+
Sbjct: 7 IGTKINLKDDDLIKYGDYMAKVK--AFNFINLPKKAKFILVTAINPTKAGEGKTTCSIGI 64
Query: 506 VKR*QHIAGRTRL 544
H+ +T L
Sbjct: 65 ADMLNHLGYQTTL 77
>UniRef50_Q6KID0 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Mycoplasma mobile|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Mycoplasma mobile
Length = 280
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/69 (39%), Positives = 40/69 (57%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K ++VID GIN+I + K + GDV + A++PVPGGVGPMTV L +N
Sbjct: 211 VKNNSIVIDVGINSIGENDKMI---VTGDVDFSNVKTKVKAISPVPGGVGPMTVISLFKN 267
Query: 186 TVQAARRQL 212
++ + L
Sbjct: 268 LIEIFEKYL 276
>UniRef50_Q9X288 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Thermotogaceae|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Thermotoga maritima
Length = 271
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/68 (45%), Positives = 43/68 (63%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K GA+VID GIN ++ +L GDV +V+ + VTPVPGGVG +T A+L +
Sbjct: 211 VKEGAIVIDVGINYVDG-------KLQGDV--DPSVEEIARVTPVPGGVGQVTTALLFEH 261
Query: 186 TVQAARRQ 209
V+AA RQ
Sbjct: 262 VVRAAERQ 269
>UniRef50_Q14NV1 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Spiroplasma citri|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Spiroplasma citri
Length = 286
Score = 54.0 bits (124), Expect = 4e-06
Identities = 27/60 (45%), Positives = 33/60 (55%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK +VID GIN ED L GD+ + +TPVPGGVGPMT+A L+ N
Sbjct: 222 IKENVIVIDVGINRDED------NNLCGDIDFHNVFSKVKMITPVPGGVGPMTIAALLEN 275
>UniRef50_Q3A1Q7 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Bacteria|Rep: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 290
Score = 54.0 bits (124), Expect = 4e-06
Identities = 37/72 (51%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAV-KVASAVTPVPGGVGPMTVAMLMR 182
I+PGAVVI GI+ G++L+ DV EAV +VA +TP GGVGP TVAML+
Sbjct: 224 IRPGAVVISGGISW-------EGRKLLPDV--DEAVGEVAGWITPRLGGVGPTTVAMLLL 274
Query: 183 NTVQAARRQLDR 218
NTVQAA + R
Sbjct: 275 NTVQAAEERARR 286
>UniRef50_Q7NAE4 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Mycoplasma gallisepticum|Rep: Bifunctional protein
folD [Includes: Methylenetetrahydrofolate dehydrogenase
(EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase
(EC 3.5.4.9)] - Mycoplasma gallisepticum
Length = 283
Score = 53.2 bits (122), Expect = 6e-06
Identities = 25/67 (37%), Positives = 40/67 (59%)
Frame = +3
Query: 9 KPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNT 188
K G + ID GI+ DP ++S + GD Y + ++AS TP PGG+GP+T+ L++N
Sbjct: 214 KRGVIFIDIGIDKYFDP-EQSKYLICGDFDYDKLKEIASYGTPTPGGIGPLTIYSLVKNL 272
Query: 189 VQAARRQ 209
+ + Q
Sbjct: 273 INLSEIQ 279
>UniRef50_A4M873 Cluster: Tetrahydrofolate
dehydrogenase/cyclohydrolase; n=1; Petrotoga mobilis
SJ95|Rep: Tetrahydrofolate dehydrogenase/cyclohydrolase
- Petrotoga mobilis SJ95
Length = 273
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++K G +VID GIN ++ ++VGDV + V +TPVPGGVG +T A+LMR
Sbjct: 208 FVKEGMIVIDVGINVVDG-------KIVGDV--NKDVSEICQLTPVPGGVGSVTTAILMR 258
Query: 183 NTVQAARRQ 209
N +AA +
Sbjct: 259 NVFRAANNK 267
>UniRef50_Q8EUQ1 Cluster: Formate--tetrahydrofolate ligase; n=1;
Mycoplasma penetrans|Rep: Formate--tetrahydrofolate
ligase - Mycoplasma penetrans
Length = 530
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/55 (41%), Positives = 32/55 (58%)
Frame = +1
Query: 529 GKNAFACMRQPSQGPTFGVKXXXXXXXYSQVIPMEEFNLHMTGDIHAVTAANNLL 693
GK + AC+RQPS GP FG+K ++ E+ N T D +A+ AANNL+
Sbjct: 67 GKESIACLRQPSMGPYFGIKGGATGSGKCEIQNPEKVNCGFTNDFYAIEAANNLI 121
Score = 37.1 bits (82), Expect = 0.44
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +2
Query: 434 KYIVVAGITPTPLGEGKSTTLIGL 505
K I+V I PTP GEGK+TTLIG+
Sbjct: 36 KLILVTSINPTPEGEGKTTTLIGI 59
>UniRef50_A3PVV6 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=8; Actinobacteridae|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Mycobacterium sp. (strain JLS)
Length = 288
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/65 (44%), Positives = 41/65 (63%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
++PGA VID G++ + +LVGDVA + +VA V+P PGGVGP+T A L+ N
Sbjct: 225 VRPGAAVIDVGVS------RDDNGKLVGDVA-PDVWEVAGHVSPNPGGVGPLTRAFLLTN 277
Query: 186 TVQAA 200
V+ A
Sbjct: 278 VVERA 282
>UniRef50_UPI00006CB712 Cluster: tetrahydrofolate
dehydrogenase/cyclohydrolase, NAD(P)-binding domain;
n=1; Tetrahymena thermophila SB210|Rep: tetrahydrofolate
dehydrogenase/cyclohydrolase, NAD(P)-binding domain -
Tetrahymena thermophila SB210
Length = 377
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/74 (40%), Positives = 45/74 (60%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K G +VID G + +S +VGDV ++ A S +TPVPGGVGP+TV+ML++N
Sbjct: 245 LKKGVIVIDVGCSRPLPHEDQSS--IVGDVEFESA----SLLTPVPGGVGPVTVSMLIQN 298
Query: 186 TVQAARRQLDRLLA 227
V+ R L++
Sbjct: 299 VVKQWERNNSVLIS 312
>UniRef50_Q97HC9 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=8; Clostridium|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Clostridium acetobutylicum
Length = 278
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/67 (38%), Positives = 39/67 (58%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++ ++VID G ++ +L GDV + E +K A+ VTPVPGGVG MT ML+
Sbjct: 219 FVNEKSIVIDVGTTVVDG-------KLRGDVVFDEVIKKAAYVTPVPGGVGAMTTTMLIL 271
Query: 183 NTVQAAR 203
N +A +
Sbjct: 272 NVCEALK 278
>UniRef50_Q189R8 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=11; Clostridiales|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Clostridium difficile (strain 630)
Length = 290
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/69 (40%), Positives = 40/69 (57%)
Frame = +3
Query: 3 WIKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMR 182
++K GAVVID GIN E+ L GDV + S +TPVP GVG +T ++L +
Sbjct: 225 FVKDGAVVIDVGINVDEEGN------LCGDVDTNAVLDKVSMITPVPAGVGSVTTSILAK 278
Query: 183 NTVQAARRQ 209
+ V+A + Q
Sbjct: 279 HVVKACKLQ 287
>UniRef50_O51057 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Borrelia burgdorferi group|Rep: Bifunctional
protein folD [Includes: Methylenetetrahydrofolate
dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate
cyclohydrolase (EC 3.5.4.9)] - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 308
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/58 (44%), Positives = 36/58 (62%)
Frame = +3
Query: 24 VIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQA 197
VID GI+ IE +G+ L GD + + +TPV GG+GP+TV MLM NT++A
Sbjct: 234 VIDIGISEIETD---NGKILSGDTDFDNIKECVKFITPVKGGIGPVTVLMLMFNTIKA 288
>UniRef50_Q04FB7 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Leuconostocaceae|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 285
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+K VVID G N K GDV +++ S ++PVPGGVGPMT+A L+++
Sbjct: 220 LKKDVVVIDVGAN-------KLNGHATGDVDFEKVYPHVSQISPVPGGVGPMTIATLIKH 272
Query: 186 TVQAA 200
T A
Sbjct: 273 TFDLA 277
>UniRef50_A5IXS7 Cluster: FolD bifunctional protein; n=1; Mycoplasma
agalactiae|Rep: FolD bifunctional protein - Mycoplasma
agalactiae
Length = 286
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQ-EAVKVASAVTPVPGGVGPMTVAMLMR 182
IK GA +ID G IE KK VGD + E ++ TP PGG+GP+TV L +
Sbjct: 218 IKDGAWLIDAGTTMIEREGKKC---FVGDASLTPEEYQLLEGYTPTPGGIGPLTVIWLFK 274
Query: 183 NTVQAAR 203
N +A +
Sbjct: 275 NLAKAIK 281
>UniRef50_Q9RW02 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Deinococcus|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Deinococcus radiodurans
Length = 299
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/68 (44%), Positives = 41/68 (60%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
++P VVID GIN E SG +VGD + V+ A TPVPGGVGP+T A++ +N
Sbjct: 234 VQPEHVVIDAGINVQE-----SGD-MVGDALPELPVR---AQTPVPGGVGPLTSALMYQN 284
Query: 186 TVQAARRQ 209
V+ + Q
Sbjct: 285 LVRGVKLQ 292
>UniRef50_Q6L046 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=2; Thermoplasmatales|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Picrophilus torridus
Length = 276
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/64 (34%), Positives = 33/64 (51%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAA 200
++ID GIN + T GD Y+ +A+TPVPGGVGP+T + N +
Sbjct: 218 IIIDVGINYLNGKT-------CGDADYENIKDYVNAITPVPGGVGPVTATDIFENFINGL 270
Query: 201 RRQL 212
+ Q+
Sbjct: 271 KYQI 274
>UniRef50_Q8EV80 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Mycoplasma penetrans|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Mycoplasma penetrans
Length = 282
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/68 (33%), Positives = 39/68 (57%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
+ P A VID GI+ ++ ++VGD A ++ + +TPVP GVG +TVAM+ +N
Sbjct: 218 VNPNAFVIDAGISVVDG-------KVVGDAA-KDLQEYVKYITPVPNGVGRLTVAMIFKN 269
Query: 186 TVQAARRQ 209
+ + +
Sbjct: 270 LMDLVKEK 277
>UniRef50_A6LP88 Cluster: Tetrahydrofolate
dehydrogenase/cyclohydrolase; n=1; Thermosipho
melanesiensis BI429|Rep: Tetrahydrofolate
dehydrogenase/cyclohydrolase - Thermosipho melanesiensis
BI429
Length = 271
Score = 41.9 bits (94), Expect = 0.016
Identities = 23/67 (34%), Positives = 41/67 (61%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
++ +++ID GIN ++ ++GDV+ + V + VTPVPGGVG +T +LM +
Sbjct: 211 VEKDSIIIDVGINVTDEG-------IIGDVS--KDVANFAKVTPVPGGVGKITTILLMEH 261
Query: 186 TVQAARR 206
V++A +
Sbjct: 262 LVKSAEK 268
>UniRef50_A1ZUI3 Cluster: Tetrahydrofolate
dehydrogenase/cyclohydrolase, NAD(P)-binding domain;
n=1; Microscilla marina ATCC 23134|Rep: Tetrahydrofolate
dehydrogenase/cyclohydrolase, NAD(P)-binding domain -
Microscilla marina ATCC 23134
Length = 233
Score = 41.1 bits (92), Expect = 0.027
Identities = 24/75 (32%), Positives = 39/75 (52%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAA 200
+++D G +E+ K + + + GDV A VTPVPGG GP+ +A+LM
Sbjct: 144 LIVDTGFVPLENVDKLTSKNVKGDVD-PTAKNKTKFVTPVPGGTGPVEMAVLMERVA--- 199
Query: 201 RRQLDRLLAPSWPLK 245
+L + PSW ++
Sbjct: 200 --KLFGIEVPSWKVE 212
>UniRef50_Q8ZZK1 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=4; Pyrobaculum|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Pyrobaculum aerophilum
Length = 311
Score = 40.7 bits (91), Expect = 0.036
Identities = 27/75 (36%), Positives = 40/75 (53%)
Frame = +3
Query: 6 IKPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
IK GAVV+ G+ DP K R DV + + AS +TP GGVG T A +++N
Sbjct: 237 IKEGAVVV--GVGGKVDPATK---RWFFDVDEKSVAEKASYLTPNIGGVGLATRARVLKN 291
Query: 186 TVQAARRQLDRLLAP 230
++ + R+L+P
Sbjct: 292 LIRTTYQVAQRVLSP 306
>UniRef50_A1ALK9 Cluster: Hydrogenase maturation protease; n=1;
Pelobacter propionicus DSM 2379|Rep: Hydrogenase
maturation protease - Pelobacter propionicus (strain DSM
2379)
Length = 201
Score = 39.9 bits (89), Expect = 0.063
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Frame = +2
Query: 227 PLLASETASLTPITPPPSDIVIARSQKPK-----DIGELAAEIGLCP----SEVSQYGRT 379
P + A P + RS KP D E+ A++G C SE+S+ +
Sbjct: 50 PFRCLDVAGFEGANAPENVTGYIRSYKPSHILVVDAAEIGAQVGFCREISISEISETNFS 109
Query: 380 KAKISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKSTTL 496
+ L V+ Q TG IVV GI P P+G + TL
Sbjct: 110 THTLPLKVIADYLEQSTGADIVVLGIQPGPVGFAMAPTL 148
>UniRef50_A5CR60 Cluster: DNA polymerase III, alpha chain; n=2;
Micrococcineae|Rep: DNA polymerase III, alpha chain -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 1140
Score = 38.7 bits (86), Expect = 0.15
Identities = 39/128 (30%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Frame = +2
Query: 149 RGAHDRGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDIGEL 328
RGA RGD A R +A ARP ++ A P+ D++ S P +
Sbjct: 939 RGAASRGDVMAYVRRLTARAARP-------ADPAGQLPLFVDDRDLIPRGSPDPDGRARV 991
Query: 329 AAEIGLCPSEVSQYGRTKAKISLSVL-----DRLRNQRTGKYIVVAGI---TPT-PLGEG 481
AAE+ + EV+++ + L L +L R+G +VVAGI T T P+ G
Sbjct: 992 AAELDILQMEVTEHVLESYRPMLDELGVIPASQLLEVRSGSEVVVAGIRIATQTPPMRSG 1051
Query: 482 KSTTLIGL 505
K I L
Sbjct: 1052 KRVVFISL 1059
>UniRef50_A7AXK7 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 276
Score = 38.3 bits (85), Expect = 0.19
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAA 200
+V+D GIN E+ K G V + ++ ++ + VTPVPGGVG +T LM+N V A
Sbjct: 214 LVVDIGINRDENG-KLCGD--VNNAGFESSLN-DTYVTPVPGGVGLLTRLTLMQNVVDAY 269
Query: 201 RRQ 209
+ Q
Sbjct: 270 KVQ 272
>UniRef50_Q0AZF5 Cluster: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Syntrophomonas wolfei subsp. wolfei str.
Goettingen|Rep: Bifunctional protein folD 1 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 277
Score = 38.3 bits (85), Expect = 0.19
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = +3
Query: 90 DVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAARRQ 209
D A E + + PVPGG+GP+ +A LM N QAAR++
Sbjct: 237 DRAALERQGFEARLLPVPGGMGPILIAKLMENLAQAARQK 276
>UniRef50_Q1Q6L6 Cluster: Similar to copper oxidase and
hydroxylamine oxidoreductase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to copper oxidase and
hydroxylamine oxidoreductase - Candidatus Kuenenia
stuttgartiensis
Length = 852
Score = 35.9 bits (79), Expect = 1.0
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 104 GGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLACPL 232
G G S GCD C + D D H+ HR +A RP AC +
Sbjct: 525 GEGYSMVGCDQCHQNMSSCD--DCHSRHRFSAAEARRPEACSI 565
>UniRef50_Q6NN19 Cluster: RE04973p; n=4; Sophophora|Rep: RE04973p -
Drosophila melanogaster (Fruit fly)
Length = 572
Score = 35.9 bits (79), Expect = 1.0
Identities = 18/69 (26%), Positives = 36/69 (52%)
Frame = +3
Query: 27 IDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAARR 206
+D N ++ T K+G + +V+ QEA K TP P V P++ +++ N + +
Sbjct: 157 VDVTANTVKANTLKTGDATMDNVSLQEAAK-----TPAPSQVYPLSANVVLENITEVSNE 211
Query: 207 QLDRLLAPS 233
+ L++P+
Sbjct: 212 GVSMLVSPA 220
>UniRef50_UPI00015B5313 Cluster: PREDICTED: similar to CG1718-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG1718-PA - Nasonia vitripennis
Length = 1646
Score = 35.5 bits (78), Expect = 1.4
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +2
Query: 254 LTPITPPPSDIVIARSQKPKD-IGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRT 430
LT + P +V+ + KD E+ +E+GLCP E + L++ L+N+
Sbjct: 520 LTGMISPTEGLVLINGKNIKDDADEIMSEMGLCPQENMVFPSLSVSEQLTIFAMLKNKNK 579
Query: 431 GKYIVVAGIT 460
K IV +T
Sbjct: 580 PKSIVEGQVT 589
>UniRef50_Q0UU61 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 225
Score = 35.5 bits (78), Expect = 1.4
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +2
Query: 170 DAHAEHRAGSAPTARPLACPLLASETASLTPITPPPSDIV-IARSQKPKDIGELAAEI 340
DAH+ RA + PTA PLA L ++ A TP +P SD + + + I +LAAE+
Sbjct: 60 DAHSPRRADAVPTAHPLAATLPLTKRAR-TPRSPRASDTMDVEDTPHRVYIHDLAAEL 116
>UniRef50_P47259 Cluster: Bifunctional protein folD [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=3; Mycoplasma|Rep: Bifunctional protein folD
[Includes: Methylenetetrahydrofolate dehydrogenase (EC
1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC
3.5.4.9)] - Mycoplasma genitalium
Length = 273
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/59 (32%), Positives = 30/59 (50%)
Frame = +3
Query: 9 KPGAVVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
K G ++ D G++ + +L GD+ + K A T PGGVGP TV +++N
Sbjct: 205 KKGVILFDIGVS------RNKQNKLCGDINPEGIEKKARWWTKTPGGVGPFTVLAIIKN 257
>UniRef50_UPI0000DD8491 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 233
Score = 35.1 bits (77), Expect = 1.8
Identities = 42/149 (28%), Positives = 58/149 (38%), Gaps = 2/149 (1%)
Frame = +2
Query: 53 GSYKEKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLACPL 232
G+ K T R G GG G C G+ G R H + +A A L
Sbjct: 11 GTPKSHSRTPRQREGARRGGGRGRGGPRCGGQGG---REGQHLRNPPPAAAAAASLRPGE 67
Query: 233 LASETASLTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKIS--LSVL 406
L++ TA L PP+ +A + E +A G +VS G + A+ S
Sbjct: 68 LSARTARLPERRQPPA--ALAPRSRAAGAAERSAAQGT--GQVSGRGDSGARAGGERSRT 123
Query: 407 DRLRNQRTGKYIVVAGITPTPLGEGKSTT 493
R + TG+ +AG TP P GE T
Sbjct: 124 GRGSSPVTGRSCPLAGWTPWPRGEAPQRT 152
>UniRef50_Q16NN2 Cluster: Brachyury; n=2; Culicidae|Rep: Brachyury -
Aedes aegypti (Yellowfever mosquito)
Length = 614
Score = 35.1 bits (77), Expect = 1.8
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Frame = +2
Query: 74 ATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLAC---PLLASE 244
A+ S + G G S+ G C+ R A A H +P A P+ P +
Sbjct: 540 ASGSSESAMMGSG-SAVGHHHCSENRSPEPNNHASANHALPGSPAAAPVGIQQSPTRSGS 598
Query: 245 TASLTPITPP 274
T + TP+TPP
Sbjct: 599 TGAWTPLTPP 608
>UniRef50_A4S4Y5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 358
Score = 34.7 bits (76), Expect = 2.4
Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 4/126 (3%)
Frame = +2
Query: 170 DAHAEHRAGSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDIGELAAEIGLC 349
+A G AP A P SET + T + PPP++++ + A+
Sbjct: 159 EAQTAMETGDAPNAVP-------SETPAATTLMPPPANVIPSPVDPTPAPTSFPAQTPAA 211
Query: 350 PSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITP-TP---LGEGKSTTLIGLVKR* 517
P++VS+ RT A + G + + G TP TP L E + L+G + R
Sbjct: 212 PAKVSEGMRTPASAGNFTPIVSSDALKGVFASLGGATPQTPPVGLPEILTPELVGPLLRD 271
Query: 518 QHIAGR 535
+ I GR
Sbjct: 272 EQIRGR 277
>UniRef50_Q2PPB3 Cluster: Histidine biosynthesis trifunctional
protein; n=16; Phaeosphaeria|Rep: Histidine biosynthesis
trifunctional protein - Phaeosphaeria nodorum (Septoria
nodorum)
Length = 881
Score = 34.7 bits (76), Expect = 2.4
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = -2
Query: 534 LPAMCCQRFTRPIRVVLLPSPSGVGVIPATTMYFPV 427
+P + C RF RPI V L P G V+P+T + V
Sbjct: 556 MPGVVCSRFARPIERVGLYVPGGTAVLPSTALMLGV 591
>UniRef50_Q0AWX5 Cluster: Bifunctional protein folD 2 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)];
n=1; Syntrophomonas wolfei subsp. wolfei str.
Goettingen|Rep: Bifunctional protein folD 2 [Includes:
Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5);
Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)] -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 272
Score = 34.7 bits (76), Expect = 2.4
Identities = 23/55 (41%), Positives = 32/55 (58%)
Frame = +3
Query: 21 VVIDCGINAIEDPTKKSGQRLVGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRN 185
VVID GIN E+ +++GDV ++EA + VPGG+G +TVA L N
Sbjct: 217 VVIDVGINFDENG------KMLGDV-HEEARNHCRLASAVPGGIGVITVAELFDN 264
>UniRef50_Q4FXT5 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major strain Friedlin
Length = 598
Score = 34.3 bits (75), Expect = 3.1
Identities = 20/61 (32%), Positives = 28/61 (45%)
Frame = +3
Query: 84 VGDVAYQEAVKVASAVTPVPGGVGPMTVAMLMRNTVQAARRQLDRLLAPSWPLKPLRSPR 263
+ DVA + A + A TP PG P+ ++ + A R L PSW L R P+
Sbjct: 63 LADVAERAAAEGALLTTPTPGSAVPLPRTAVLSGSGPGAPRLAHTFLMPSWSLLE-RDPK 121
Query: 264 L 266
L
Sbjct: 122 L 122
>UniRef50_P07685 Cluster: Histidine biosynthesis trifunctional
protein [Includes: Phosphoribosyl-AMP cyclohydrolase (EC
3.5.4.19); Phosphoribosyl-ATP pyrophosphohydrolase (EC
3.6.1.31); Histidinol dehydrogenase (EC 1.1.1.23)
(HDH)]; n=9; Fungi/Metazoa group|Rep: Histidine
biosynthesis trifunctional protein [Includes:
Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19);
Phosphoribosyl-ATP pyrophosphohydrolase (EC 3.6.1.31);
Histidinol dehydrogenase (EC 1.1.1.23) (HDH)] -
Neurospora crassa
Length = 870
Score = 34.3 bits (75), Expect = 3.1
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = -2
Query: 534 LPAMCCQRFTRPIRVVLLPSPSGVGVIPATTMYFPV 427
+P + C RF+RPI V P G V+P+T + V
Sbjct: 541 MPGVVCSRFSRPIEAVGCYIPGGTAVLPSTALMLGV 576
>UniRef50_UPI0000E2417F Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 144
Score = 33.9 bits (74), Expect = 4.1
Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Frame = +2
Query: 59 YKEKRATFSG-RRGLPGGGQSS---FGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLAC 226
++E+R SG RR P G G +C+ R+G RG+A A RP
Sbjct: 30 FRERRRALSGPRRPRPSSGNRCPPRKGRKNCSARKGEELRGEARPRRGQRQAARVRPRPL 89
Query: 227 PLLASETASLTPIT--PPPSDIVIARSQKPKDIG 322
+ A T +T PP ++ AR+++P+ G
Sbjct: 90 GPRRARGALGTAVTHAPPATERRGARARRPRGRG 123
>UniRef50_Q55365 Cluster: Endo-1,4-beta-glucanase; n=1;
Synechocystis sp. PCC 6803|Rep: Endo-1,4-beta-glucanase
- Synechocystis sp. (strain PCC 6803)
Length = 1070
Score = 33.9 bits (74), Expect = 4.1
Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 3/82 (3%)
Frame = +2
Query: 86 GRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLACPLLASETAS---L 256
G + PG G + G +G G H G H +H G + T +
Sbjct: 359 GHQSRPGNGLTPIGGGEFSGGAGGHGSGHDHGDHDHGGGMDHGSDPGDGMGGGTTNPPVT 418
Query: 257 TPITPPPSDIVIARSQKPKDIG 322
P+TPPP+D V S +G
Sbjct: 419 DPVTPPPTDPVSPTSPFTVTVG 440
>UniRef50_A7EN88 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 430
Score = 33.9 bits (74), Expect = 4.1
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +2
Query: 167 GDAHAEHRAGSAPTARP--LACPLLASETASLTPITPPPSDIVIARSQKPKDIGELAAEI 340
GDA + ++P P + P+ + L P P PS + + PK + A+
Sbjct: 159 GDADDDQSFTNSPEVGPTSVTSPIASGIADMLEPAAPGPSVLKVTEPTNPKPAKKEKAKA 218
Query: 341 GLCPSEVSQYGRTKAKISLSVLDRLRNQRTGK 436
P+E + + +AKI + L R + ++ K
Sbjct: 219 APQPTETKKQRQNRAKIEAAKLVREQEEKERK 250
>UniRef50_UPI00004EBBDF Cluster: Hypothetical protein MuHV1gpm30;
n=1; Murid herpesvirus 1|Rep: Hypothetical protein
MuHV1gpm30 - Murid herpesvirus 1
Length = 281
Score = 33.5 bits (73), Expect = 5.5
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 9/62 (14%)
Frame = +2
Query: 134 SCAGRR-GAHDRGDAHAEHRAGSAPTAR---PLACPLLASETASL-----TPITPPPSDI 286
S A R G H + A HR G PT R PL+ + S T+S+ T +TPPPS
Sbjct: 152 SAASRAPGRHQLPSSGAAHRRGRTPTRRITVPLSKTCVVSRTSSIRIMRSTSVTPPPSPK 211
Query: 287 VI 292
+I
Sbjct: 212 LI 213
>UniRef50_Q4T9M8 Cluster: Chromosome undetermined SCAF7533, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7533,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1291
Score = 33.5 bits (73), Expect = 5.5
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = -2
Query: 258 VSEAVSEAKRGQASGRAVGALPARCSA*ASPRSWAPRRPAQESQ 127
V++ SEA+ S G P +C AS SW+ PAQE Q
Sbjct: 372 VTQVFSEAELSNLSNHGDGRQPQQCLLSASGPSWSSESPAQECQ 415
>UniRef50_Q91TP2 Cluster: T47; n=1; Tupaiid herpesvirus 1|Rep: T47 -
Tupaiid herpesvirus 1 (strain 1) (TuHV-1) (Herpesvirus
tupaia (strain1))
Length = 1055
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/32 (46%), Positives = 18/32 (56%)
Frame = +2
Query: 191 AGSAPTARPLACPLLASETASLTPITPPPSDI 286
AGSAP P P S+ + TP PPPSD+
Sbjct: 174 AGSAPPTTPRTQPTKTSKKSKSTPPPPPPSDL 205
>UniRef50_Q08SH7 Cluster: Translation initiation factor SUI1 family;
n=1; Stigmatella aurantiaca DW4/3-1|Rep: Translation
initiation factor SUI1 family - Stigmatella aurantiaca
DW4/3-1
Length = 143
Score = 33.5 bits (73), Expect = 5.5
Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Frame = +2
Query: 143 GRRGAHDRGDAHAEHRA-GSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDI 319
G R D+G H A S A P A P + +E LTP T P+ V+ Q+
Sbjct: 23 GYRDPKDKGRFHNPFAALASQRAAVPGAQPQIRAEDFPLTPPTEGPAQAVLRLEQRGGQE 82
Query: 320 GELAAEIGLCPSEVSQY 370
L +GL P E+ +
Sbjct: 83 VTLVEGLGLAPPEMQAW 99
>UniRef50_A7DDM2 Cluster: Smr protein/MutS2; n=2; Methylobacterium
extorquens PA1|Rep: Smr protein/MutS2 - Methylobacterium
extorquens PA1
Length = 256
Score = 33.5 bits (73), Expect = 5.5
Identities = 17/51 (33%), Positives = 26/51 (50%)
Frame = +2
Query: 188 RAGSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDIGELAAEI 340
+ + P RP + P AS A P+ P P+ + + KP +G+LA EI
Sbjct: 72 KPAAKPAWRPASPPPAASALAKPAPLKPAPAASLSRVASKPLKLGDLAPEI 122
>UniRef50_A1WX06 Cluster: Putative uncharacterized protein; n=1;
Halorhodospira halophila SL1|Rep: Putative
uncharacterized protein - Halorhodospira halophila
(strain DSM 244 / SL1) (Ectothiorhodospirahalophila
(strain DSM 244 / SL1))
Length = 434
Score = 33.5 bits (73), Expect = 5.5
Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 4/113 (3%)
Frame = +2
Query: 83 SGRRGLPGGGQSSFGCD-SCAGRRGAHDRG-DAHAEHRAGSAPTARPLACPLLASETASL 256
SGR G GG + G S GRR A R ++ A TA + S+
Sbjct: 81 SGRSGEQGGAAKTRGKPGSSKGRRLAGKRVLESPAPEADAGGATAESIEAEQPEEALPSV 140
Query: 257 TP--ITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLD 409
T I P ++V+ + P D E AA+ + P E+ + G +A +V D
Sbjct: 141 TGEVIVEPEPEVVVDEQRDPADEAEGAADAEMDPEELLEIGLERADRGDAVYD 193
>UniRef50_Q6YXJ2 Cluster: Putative uncharacterized protein
B1029H08.29; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
B1029H08.29 - Oryza sativa subsp. japonica (Rice)
Length = 172
Score = 33.5 bits (73), Expect = 5.5
Identities = 21/70 (30%), Positives = 33/70 (47%)
Frame = +2
Query: 53 GSYKEKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLACPL 232
G+ +E+R+ GRR GGG D+ A +G G A + S+P A+P +C
Sbjct: 35 GAMRERRS--GGRRRRGGGGDGDGDDDAGAREQGGGGDGGVGAGELSPSSPRAQPRSCSS 92
Query: 233 LASETASLTP 262
+ + T P
Sbjct: 93 VDAATKGNPP 102
>UniRef50_Q5CN90 Cluster: Last step in pyrimidine biosynthesis
pathway; Ura8p; n=2; Cryptosporidium|Rep: Last step in
pyrimidine biosynthesis pathway; Ura8p - Cryptosporidium
hominis
Length = 670
Score = 33.5 bits (73), Expect = 5.5
Identities = 19/46 (41%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Frame = +2
Query: 371 GRTKA-KISLSVLDRLRNQRTGKYIVVAGITPTPLGEGKSTTLIGL 505
GR K+ K++ S ++ L + R KYIVV G T + LG+G + + +GL
Sbjct: 10 GRIKSPKLTTSSVNHLADDRVIKYIVVTGGTLSGLGKGIAISSLGL 55
>UniRef50_Q7S5B5 Cluster: Putative uncharacterized protein
NCU02249.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU02249.1 - Neurospora crassa
Length = 742
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/47 (31%), Positives = 23/47 (48%)
Frame = +2
Query: 140 AGRRGAHDRGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPPS 280
AG + HD AH R+ + P P + ++T S+ P PPP+
Sbjct: 243 AGGQARHDSTTAHGHGRSATGPVVLPHHSIVGQNKTISMAPSVPPPT 289
>UniRef50_A3LSS5 Cluster: Histidine biosynthesis trifunctional
protein; n=7; Eukaryota|Rep: Histidine biosynthesis
trifunctional protein - Pichia stipitis (Yeast)
Length = 867
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/35 (42%), Positives = 19/35 (54%)
Frame = -2
Query: 531 PAMCCQRFTRPIRVVLLPSPSGVGVIPATTMYFPV 427
P + C RF +PI V L P G V+P+T M V
Sbjct: 538 PGVYCSRFAKPIENVGLYVPGGTAVLPSTAMMLGV 572
>UniRef50_P00815 Cluster: Histidine biosynthesis trifunctional
protein [Includes: Phosphoribosyl-AMP cyclohydrolase (EC
3.5.4.19); Phosphoribosyl-ATP pyrophosphohydrolase (EC
3.6.1.31); Histidinol dehydrogenase (EC 1.1.1.23)
(HDH)]; n=10; cellular organisms|Rep: Histidine
biosynthesis trifunctional protein [Includes:
Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19);
Phosphoribosyl-ATP pyrophosphohydrolase (EC 3.6.1.31);
Histidinol dehydrogenase (EC 1.1.1.23) (HDH)] -
Saccharomyces cerevisiae (Baker's yeast)
Length = 799
Score = 33.5 bits (73), Expect = 5.5
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -2
Query: 531 PAMCCQRFTRPIRVVLLPSPSGVGVIPATTMYFPV 427
P + C RF RPI V L P G ++P+T + V
Sbjct: 466 PGVLCSRFPRPIEKVGLYIPGGTAILPSTALMLGV 500
>UniRef50_UPI0000E24696 Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 396
Score = 33.1 bits (72), Expect = 7.2
Identities = 19/52 (36%), Positives = 25/52 (48%)
Frame = +2
Query: 68 KRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLA 223
+R GRR GGG+ + + GRR A G A + +AP ARP A
Sbjct: 333 RREAAGGRREAGGGGRGAQSGSAAGGRREAGAGGWAPQRSQRSAAPRARPHA 384
>UniRef50_Q14839-2 Cluster: Isoform 2 of Q14839 ; n=19;
Euteleostomi|Rep: Isoform 2 of Q14839 - Homo sapiens
(Human)
Length = 1940
Score = 33.1 bits (72), Expect = 7.2
Identities = 15/44 (34%), Positives = 21/44 (47%)
Frame = -1
Query: 274 RWRNRGERSGFRGQEGASKRSSCRRAACTVFRMSIATVMGPTPP 143
+WR + F+G GAS ++ A V M AT + P PP
Sbjct: 208 KWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPP 251
>UniRef50_Q2LXV3 Cluster: Methyl-viologen-reducing hydrogenase,
delta subunit; n=6; Deltaproteobacteria|Rep:
Methyl-viologen-reducing hydrogenase, delta subunit -
Syntrophus aciditrophicus (strain SB)
Length = 214
Score = 33.1 bits (72), Expect = 7.2
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +2
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQYGRTKAKISL 397
S+I+ Q+P GE+A +GL PS VS++ T +K L
Sbjct: 162 SEIMSLLRQQPLSTGEIAQRLGLTPSAVSRHMNTSSKHGL 201
>UniRef50_Q0EZ74 Cluster: Translation initiation factor IF-2; n=1;
Mariprofundus ferrooxydans PV-1|Rep: Translation
initiation factor IF-2 - Mariprofundus ferrooxydans PV-1
Length = 1045
Score = 33.1 bits (72), Expect = 7.2
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 5/121 (4%)
Frame = +2
Query: 134 SCAGRRGAHDRGDAHAEHRAGSAP---TARP--LACPLLASETASLTPITPPPSDIVIAR 298
+ A ++ A D A +E A AP ++P A P ++ ETA+ +P+T P
Sbjct: 151 AAAEQQKAADAKAAASEPAAAEAPKVPASKPEVAAQPAVSRETATKSPVTRQPIKRQAGV 210
Query: 299 SQKPKDIGELAAEIGLCPSEVSQYGRTKAKISLSVLDRLRNQRTGKYIVVAGITPTPLGE 478
+ KP D + + P+EV++ A + + NQ A TP G
Sbjct: 211 ASKPTDTPGVVRRSAVNPAEVARSKIAAAAAARTAAQEKSNQERVARQRAAQTRNTPAGT 270
Query: 479 G 481
G
Sbjct: 271 G 271
>UniRef50_Q02AS0 Cluster: Putative uncharacterized protein
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
Putative uncharacterized protein precursor - Solibacter
usitatus (strain Ellin6076)
Length = 631
Score = 33.1 bits (72), Expect = 7.2
Identities = 24/78 (30%), Positives = 35/78 (44%)
Frame = -1
Query: 244 FRGQEGASKRSSCRRAACTVFRMSIATVMGPTPPGTGVTAEATLTASW*ATSPTKRCPLF 65
+ GQ + + + A T+ +SI P P G TA T+T + A PT
Sbjct: 524 YLGQRQTIQLTVSPQTAATLSALSIV----PNPVTGGTTAVGTITLTGQAVGPT--LVTL 577
Query: 64 FVGSSIALIPQSITTAPG 11
F S+IA +P S+T G
Sbjct: 578 FSNSAIAFVPASVTVPQG 595
>UniRef50_A4X3P9 Cluster: Putative uncharacterized protein; n=1;
Salinispora tropica CNB-440|Rep: Putative
uncharacterized protein - Salinispora tropica CNB-440
Length = 281
Score = 33.1 bits (72), Expect = 7.2
Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 7/103 (6%)
Frame = +2
Query: 2 LDQAWSGRYRLWYQRY*GSYKEKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHA 181
LD A+ R R W ++ +KE A RR L GGG + G + A D A
Sbjct: 181 LDPAYMRRMRGWSEQ---EWKEAEAALVDRRLLTGGGLTVAGRELRAEVERWTDMAAAAP 237
Query: 182 EHRAGSAPTA--RPLACPLL-----ASETASLTPITPPPSDIV 289
G+ PTA R L P++ +E+ + P+ P++IV
Sbjct: 238 WQALGAGPTARLRDLMTPVVQRLSELNESMKVNPMALNPAEIV 280
>UniRef50_A4VQJ8 Cluster: Transcriptional regulator, AraC family;
n=2; Pseudomonas|Rep: Transcriptional regulator, AraC
family - Pseudomonas stutzeri (strain A1501)
Length = 346
Score = 33.1 bits (72), Expect = 7.2
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Frame = +2
Query: 65 EKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLA-C-PLLA 238
E+ A F GR F SC RR A +R A+ A A RP C P+
Sbjct: 13 ERDAAFDGRFVFAVRSTGIFCRPSCPARRPARERVAFFADGEAARAAGFRPCRRCSPMGP 72
Query: 239 SETASLTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQ 367
S + L + + + + P + +LAA IGL P+ +++
Sbjct: 73 SPSEQLDALVVAACRL-LDEATGPMTLPQLAARIGLSPTHLAR 114
>UniRef50_Q75I35 Cluster: Putative uncharacterized protein
Os03g40910; n=2; Oryza sativa|Rep: Putative
uncharacterized protein Os03g40910 - Oryza sativa subsp.
japonica (Rice)
Length = 273
Score = 33.1 bits (72), Expect = 7.2
Identities = 28/94 (29%), Positives = 33/94 (35%), Gaps = 5/94 (5%)
Frame = +2
Query: 14 WSGRYRLWYQRY*GSYKEKRATFSGRRGLPGGG-----QSSFGCDSCAGRRGAHDRGDAH 178
W GR R W+ R + + G G GGG SS G S G GD
Sbjct: 98 WLGRRRRWWARATAAVDGLGDSGGGGLGDGGGGGLGGGGSSGGEGSGGGSSDGEGCGDGS 157
Query: 179 AEHRAGSAPTARPLACPLLASETASLTPITPPPS 280
G PT R A P +P +PP S
Sbjct: 158 GGGELGGGPTVRRRASPPARPRWWPCSPSSPPAS 191
>UniRef50_Q4D315 Cluster: Putative uncharacterized protein; n=2;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 2097
Score = 33.1 bits (72), Expect = 7.2
Identities = 23/64 (35%), Positives = 29/64 (45%)
Frame = +2
Query: 152 GAHDRGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDIGELA 331
G D GD A S + A L A T SL P + PPS + RS +P+ + LA
Sbjct: 282 GEDDNGDTLASGSPSSNTPGKVNAADLEALMTESLVPHSMPPSTPISTRSGEPRFL-PLA 340
Query: 332 AEIG 343
E G
Sbjct: 341 TETG 344
>UniRef50_A5K1V8 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 2977
Score = 33.1 bits (72), Expect = 7.2
Identities = 25/69 (36%), Positives = 34/69 (49%)
Frame = +2
Query: 8 QAWSGRYRLWYQRY*GSYKEKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEH 187
+A G Y++ Y GSY K + G G G G + G SCAG GA+D G ++
Sbjct: 448 RASGGNYQVAVNNYDGSYVSK--NYGGSGGGGGNGHGNLGA-SCAG--GANDPG-GNSHS 501
Query: 188 RAGSAPTAR 214
RA S+ R
Sbjct: 502 RAVSSGACR 510
>UniRef50_Q9UMR3 Cluster: T-box transcription factor TBX20; n=34;
Coelomata|Rep: T-box transcription factor TBX20 - Homo
sapiens (Human)
Length = 297
Score = 33.1 bits (72), Expect = 7.2
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 3/140 (2%)
Frame = +2
Query: 53 GSYKEKRATFSGRRGLPGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGSAPTARPLACPL 232
G KEK AT + + L + S SCA G DAH E GS + P + L
Sbjct: 27 GGSKEKEATENTIKPLEQFVEKS----SCAQPLGELTSLDAHGEFGGGSGSS--PSSSSL 80
Query: 233 LASETASLTPITPPPSDIVIARSQKPKDIGELAAEIGLCPSEVSQYGR---TKAKISLSV 403
TPI P IA S + K++ + E+G +++ GR ++S S
Sbjct: 81 CTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELG-TEMIITKSGRRMFPTIRVSFSG 139
Query: 404 LDRLRNQRTGKYIVVAGITP 463
+D KYIV+ I P
Sbjct: 140 VD-----PEAKYIVLMDIVP 154
>UniRef50_UPI0000EBEFAE Cluster: PREDICTED: hypothetical protein,
partial; n=1; Bos taurus|Rep: PREDICTED: hypothetical
protein, partial - Bos taurus
Length = 343
Score = 32.7 bits (71), Expect = 9.5
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 137 CAGRRGAHDRGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPP 277
C GA R E RA S P PLA + LTP+ PPP
Sbjct: 129 CRRPLGARSRRPGEVEPRARSPPPRGPLAPRQPGPPSPGLTPLPPPP 175
>UniRef50_UPI000023D465 Cluster: hypothetical protein FG10402.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10402.1 - Gibberella zeae PH-1
Length = 1187
Score = 32.7 bits (71), Expect = 9.5
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Frame = -1
Query: 166 TVMGPTPPGTGVTAEAT-LTASW*ATSPTKRCPLFFVGSSIALIPQSITTAPGLI 5
TV+ P PP T TAEA+ TA+W +SP + + +I P+S TT P I
Sbjct: 34 TVVSPFPPATANTAEASPPTAAWTWSSPPPTPTVNRLSVNIP-FPRSATTTPVFI 87
>UniRef50_Q13H21 Cluster: Putative FAD dependent oxidoreductase;
n=1; Burkholderia xenovorans LB400|Rep: Putative FAD
dependent oxidoreductase - Burkholderia xenovorans
(strain LB400)
Length = 442
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = -2
Query: 321 PMSLGF*ERAITMSLGGGVIGVSEAVSEAKRG 226
P S GF +R +GGG+IGVS A A+RG
Sbjct: 8 PNSDGFPDRCDVAVIGGGIIGVSTAYELARRG 39
>UniRef50_A3VQT7 Cluster: ATP-dependent protease peptidase subunit;
n=1; Parvularcula bermudensis HTCC2503|Rep:
ATP-dependent protease peptidase subunit - Parvularcula
bermudensis HTCC2503
Length = 112
Score = 32.7 bits (71), Expect = 9.5
Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Frame = +2
Query: 119 SFGC-DSCAGRRGAHDRGDAHAEHRAGSAPTA-RPLACPLLASETASLTPITPPPSDIVI 292
SF C SC G +G +RG R A A R C L ETASLTP ++
Sbjct: 9 SFVCLASCGGPQGQFERGCQTLVKRDRDATAAQRDAFCTCLREETASLTPAEKRAYGRLM 68
Query: 293 ARSQK----PKDIGELAAEIGLCPSEVSQYGRTKAKISLS 400
A ++ + +GE++ E L S V + +LS
Sbjct: 69 AEAETGQILRERLGEMSEEGELTASGVKTFLSAAKSCTLS 108
>UniRef50_Q6ATH5 Cluster: Putative uncharacterized protein
OSJNBa0093E24.6; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OSJNBa0093E24.6 - Oryza sativa subsp. japonica (Rice)
Length = 293
Score = 32.7 bits (71), Expect = 9.5
Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Frame = +2
Query: 83 SGRRGLPGGGQSSFGCDSCAGRRGAHDRG-DAHAEHRA--------GSAPTARPLACPLL 235
SGRR GGG C + RR DRG DA A RA G A T R + +L
Sbjct: 24 SGRRRSAGGGDGCGRCGGGSQRRAGEDRGADADAGRRARRRQRVAGGGAATVRSILVVVL 83
Query: 236 ASETASLTPITP-PPSDIVIARSQKP 310
P P PP IA S P
Sbjct: 84 LIPPRWRRPPPPLPPRCSAIACSLPP 109
>UniRef50_Q00SR1 Cluster: 10-formyltetra; n=1; Ostreococcus
tauri|Rep: 10-formyltetra - Ostreococcus tauri
Length = 467
Score = 32.7 bits (71), Expect = 9.5
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +1
Query: 643 LHMTGDIHAVTAANNLLAA 699
LH+TGDIHA+ A NL+AA
Sbjct: 2 LHLTGDIHAIGVATNLVAA 20
>UniRef50_A4H9T3 Cluster: Protein kinase; n=1; Leishmania
braziliensis|Rep: Protein kinase - Leishmania
braziliensis
Length = 1036
Score = 32.7 bits (71), Expect = 9.5
Identities = 19/63 (30%), Positives = 31/63 (49%)
Frame = +2
Query: 152 GAHDRGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPPSDIVIARSQKPKDIGELA 331
G+ G A E + ++ L P L S +T + P PS +A SQ+P+ + E+A
Sbjct: 77 GSSGSGGALNEVNTAAQTSSSSLRGPQLRSSVL-ITRVAPAPSTASVASSQRPRVLPEIA 135
Query: 332 AEI 340
A +
Sbjct: 136 ASV 138
>UniRef50_Q4PBD7 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1399
Score = 32.7 bits (71), Expect = 9.5
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = +2
Query: 164 RGDAHAEHRAGSAPTARPLACPLLASETASLTPITPPPS 280
R AH R+G+ +A + L AS + S+ P TPPPS
Sbjct: 1212 RASAHMRDRSGTGASADGSSQTLAASSSLSVFPNTPPPS 1250
>UniRef50_Q2HFX2 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 817
Score = 32.7 bits (71), Expect = 9.5
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -2
Query: 534 LPAMCCQRFTRPIRVVLLPSPSGVGVIPATTMYFPV 427
+P + C RF+RP V L P G V+P+T V
Sbjct: 516 IPGVVCSRFSRPPEAVGLYVPGGTAVLPSTAFMLGV 551
>UniRef50_A7F9H5 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 1513
Score = 32.7 bits (71), Expect = 9.5
Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
Frame = +2
Query: 101 PGGGQSSFGCDSCAGRRGAHDRGDAHAEHRAGS-APTARPLACPLLASETASLTPITPPP 277
P G FG S +G ++ G A A+ A +A+P A P AS A P PP
Sbjct: 801 PASGGGLFG--SASGSTKSNPFGSAEAKLAPNPFAASAKPAANPFDASIPAKTAPAPSPP 858
Query: 278 SDIVIARSQKPKDIGELAAEIGLCPSEVSQY--GRTKA 385
DI Q+P D G A + P+ S Y G T A
Sbjct: 859 LDI----KQEPND-GVPEAPLPPDPTSKSSYAAGETSA 891
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 755,207,552
Number of Sequences: 1657284
Number of extensions: 15964105
Number of successful extensions: 62607
Number of sequences better than 10.0: 160
Number of HSP's better than 10.0 without gapping: 58040
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 62457
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59265488880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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