SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbVm0174
         (710 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to 5-formylte...    90   6e-17
UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;...    80   6e-14
UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep...    79   1e-13
UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella ve...    77   4e-13
UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    76   1e-12
UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    73   7e-12
UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    70   7e-11
UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate cyclo...    62   2e-08
UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1; ...    61   2e-08
UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    60   7e-08
UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;...    56   7e-07
UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1; ...    56   7e-07
UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    55   2e-06
UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    55   2e-06
UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    55   2e-06
UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    54   3e-06
UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    54   3e-06
UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    54   3e-06
UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2; Ostre...    54   5e-06
UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    53   8e-06
UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    53   8e-06
UniRef50_A6RBY2 Cluster: Predicted protein; n=1; Ajellomyces cap...    53   8e-06
UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetas...    53   8e-06
UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    52   1e-05
UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    52   1e-05
UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    52   1e-05
UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate cyclo...    52   2e-05
UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    51   2e-05
UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate cyclo...    51   2e-05
UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces cere...    51   2e-05
UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    51   3e-05
UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    51   3e-05
UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    51   3e-05
UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    51   3e-05
UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    51   3e-05
UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    50   4e-05
UniRef50_Q830J1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    50   6e-05
UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l...    50   6e-05
UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    50   7e-05
UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2; ...    49   1e-04
UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    49   1e-04
UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    49   1e-04
UniRef50_Q03RP0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    49   1e-04
UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    49   1e-04
UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    49   1e-04
UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    49   1e-04
UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    48   2e-04
UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   2e-04
UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   2e-04
UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   2e-04
UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   2e-04
UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    48   2e-04
UniRef50_Q03UF8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   2e-04
UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   3e-04
UniRef50_Q1NVQ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   3e-04
UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   3e-04
UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   3e-04
UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    48   3e-04
UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1; ...    48   3e-04
UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    47   4e-04
UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   4e-04
UniRef50_A6EDM4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   4e-04
UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    47   4e-04
UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   4e-04
UniRef50_Q8Y7E7 Cluster: Lmo1336 protein; n=13; Listeria|Rep: Lm...    47   5e-04
UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   5e-04
UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   5e-04
UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   5e-04
UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    47   5e-04
UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces cere...    47   5e-04
UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC ...    46   7e-04
UniRef50_Q2JU73 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    46   7e-04
UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1; ...    46   7e-04
UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   7e-04
UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    46   7e-04
UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   7e-04
UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate cyclo...    46   0.001
UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.001
UniRef50_Q8DK86 Cluster: Tll0980 protein; n=1; Synechococcus elo...    46   0.001
UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate cyclo...    46   0.001
UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    46   0.001
UniRef50_Q4D2J6 Cluster: Putative uncharacterized protein; n=2; ...    46   0.001
UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    45   0.002
UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    45   0.002
UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    45   0.002
UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    45   0.002
UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyc...    45   0.002
UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    45   0.002
UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    45   0.002
UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    45   0.002
UniRef50_Q08SB2 Cluster: 5,10-methenyltetrahydrofolate synthetas...    45   0.002
UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1; ...    45   0.002
UniRef50_A6G5C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.003
UniRef50_A4CIN4 Cluster: Putative uncharacterized protein; n=1; ...    44   0.003
UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.003
UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.003
UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    44   0.004
UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_Q3A217 Cluster: Putative ligase; n=1; Pelobacter carbin...    44   0.004
UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    44   0.004
UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.004
UniRef50_Q57W74 Cluster: Putative uncharacterized protein; n=1; ...    44   0.004
UniRef50_Q9P7W2 Cluster: Putative 5-formyltetrahydrofolate cyclo...    44   0.004
UniRef50_Q92HS7 Cluster: Similarity to 5-formyltetrahydrofolate ...    44   0.005
UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep...    44   0.005
UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.005
UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.005
UniRef50_A6UKG2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    44   0.005
UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    44   0.005
UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1; ...    44   0.005
UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2; Baci...    44   0.005
UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23; Ent...    44   0.005
UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1; ...    43   0.006
UniRef50_Q4ULB4 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ...    43   0.006
UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetas...    43   0.006
UniRef50_Q11X92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.006
UniRef50_Q03B49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.006
UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.006
UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3; ...    43   0.006
UniRef50_Q7NMK6 Cluster: Glr0759 protein; n=1; Gloeobacter viola...    43   0.009
UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.009
UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.009
UniRef50_Q0AVU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    43   0.009
UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate cyclo...    43   0.009
UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    43   0.009
UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    43   0.009
UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    43   0.009
UniRef50_UPI0000E87FAB Cluster: 5-formyltetrahydrofolate cyclo-l...    42   0.011
UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ...    42   0.011
UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    42   0.011
UniRef50_Q1IX36 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.011
UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.011
UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.011
UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16; G...    42   0.011
UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2; ...    42   0.015
UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.015
UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1; ...    42   0.015
UniRef50_A5GM63 Cluster: Putative uncharacterized protein SynWH7...    42   0.015
UniRef50_Q4QB50 Cluster: Putative uncharacterized protein; n=3; ...    42   0.015
UniRef50_Q89AD6 Cluster: Uncharacterized protein bbp_370; n=1; B...    42   0.015
UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolat...    42   0.020
UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    42   0.020
UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    42   0.020
UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    41   0.026
UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    41   0.026
UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate cyclo...    41   0.026
UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.026
UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate cyclo...    41   0.026
UniRef50_Q0P948 Cluster: Putative 5-formyltetrahydrofolate cyclo...    41   0.026
UniRef50_Q0BT60 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.026
UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    41   0.026
UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.026
UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate cycloli...    41   0.035
UniRef50_Q46JY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1; ...    41   0.035
UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1; ...    41   0.035
UniRef50_A2C833 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_A1B1U2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    41   0.035
UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1; ...    40   0.046
UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1; ...    40   0.046
UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.046
UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.046
UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.046
UniRef50_UPI000050F91E Cluster: COG0212: 5-formyltetrahydrofolat...    40   0.060
UniRef50_Q88WQ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.060
UniRef50_A0Z2P3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.060
UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5; ...    40   0.060
UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.080
UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1; ...    40   0.080
UniRef50_A7I2Y8 Cluster: 5,10-methenyltetrahydrofolate synthetas...    40   0.080
UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.080
UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    40   0.080
UniRef50_A1ZJP2 Cluster: 5,10-methenyltetrahydrofolate synthetas...    40   0.080
UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4; ...    40   0.080
UniRef50_Q1JSS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    40   0.080
UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    39   0.11 
UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    39   0.11 
UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp....    39   0.11 
UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.11 
UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.11 
UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.11 
UniRef50_A6GU56 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein Rgryl_01000...    39   0.14 
UniRef50_Q3AZ02 Cluster: Putative uncharacterized protein; n=2; ...    39   0.14 
UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1; ...    39   0.14 
UniRef50_A3J2X7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_A1FY99 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_A0RNB2 Cluster: 5,10-methenyltetrahydrofolate synthetas...    39   0.14 
UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    39   0.14 
UniRef50_Q9Z7E3 Cluster: Formyltetrahydrofolate Cycloligase; n=4...    38   0.18 
UniRef50_Q6MNQ4 Cluster: InterPro: 5-formyltetrahydrofolate cycl...    38   0.18 
UniRef50_Q5NR15 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.18 
UniRef50_Q0F944 Cluster: Putative 5-formyltetrahydrofolate cyclo...    38   0.18 
UniRef50_A7BS36 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.18 
UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.18 
UniRef50_A3YY34 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_A1BBF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.18 
UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1; ...    38   0.24 
UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.24 
UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    38   0.24 
UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.24 
UniRef50_O26306 Cluster: Conserved protein; n=1; Methanothermoba...    38   0.24 
UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.32 
UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.32 
UniRef50_Q4E7I6 Cluster: Protein; n=5; Wolbachia|Rep: Protein - ...    38   0.32 
UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    38   0.32 
UniRef50_Q12FT0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.32 
UniRef50_A2SL05 Cluster: Putative uncharacterized protein; n=1; ...    38   0.32 
UniRef50_A1G3P7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    38   0.32 
UniRef50_Q2H2V3 Cluster: Putative uncharacterized protein; n=1; ...    38   0.32 
UniRef50_UPI0000E0F49C Cluster: hypothetical 5-formyltetrahydrof...    37   0.43 
UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.43 
UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.43 
UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate cyclo...    37   0.43 
UniRef50_Q15Q29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.43 
UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ...    37   0.43 
UniRef50_A2U0W8 Cluster: Putative uncharacterized protein; n=3; ...    37   0.43 
UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.43 
UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Re...    37   0.43 
UniRef50_Q4JU08 Cluster: Putative uncharacterized protein; n=1; ...    37   0.56 
UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.56 
UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.56 
UniRef50_A3U5R6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    37   0.56 
UniRef50_Q9PLS7 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ...    36   0.74 
UniRef50_Q477X4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.74 
UniRef50_Q9F7S8 Cluster: Predicted 5-formyltetrahydrofolate cycl...    36   0.74 
UniRef50_Q2CK01 Cluster: Putative uncharacterized protein; n=6; ...    36   0.74 
UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.74 
UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.74 
UniRef50_A5GRX1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    36   0.74 
UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.74 
UniRef50_A4B9S4 Cluster: Putative carbon-nitrogen ligase; n=1; R...    36   0.74 
UniRef50_A3UGX7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.74 
UniRef50_Q8I4Y1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.74 
UniRef50_UPI00015BCCCB Cluster: UPI00015BCCCB related cluster; n...    36   0.98 
UniRef50_Q89U90 Cluster: Blr1527 protein; n=1; Bradyrhizobium ja...    36   0.98 
UniRef50_Q6N1F2 Cluster: Antifreeze protein, type I:5-formyltetr...    36   0.98 
UniRef50_Q1VH78 Cluster: Probable 5-formyltetrahydrofolate cyclo...    36   0.98 
UniRef50_Q1GTI6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.98 
UniRef50_A6WEB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.98 
UniRef50_A6PRD6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.98 
UniRef50_A5P2B9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   0.98 
UniRef50_A3TPS1 Cluster: Putative ligase; n=1; Janibacter sp. HT...    36   0.98 
UniRef50_A1K2Q9 Cluster: , complete genome; n=2; Azoarcus|Rep: ,...    36   0.98 
UniRef50_A0NLR0 Cluster: Putative uncharacterized protein; n=1; ...    36   0.98 
UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    36   1.3  
UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni ACN1...    36   1.3  
UniRef50_A7GY22 Cluster: 5,10-methenyltetrahydrofolate synthetas...    36   1.3  
UniRef50_A1URD6 Cluster: 5,10-methenyltetrahydrofolate synthetas...    36   1.3  
UniRef50_A2BIS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    36   1.3  
UniRef50_Q6FD61 Cluster: Putative ligase; n=3; Acinetobacter|Rep...    35   1.7  
UniRef50_Q62G39 Cluster: Type I secretion outer membrane protein...    35   1.7  
UniRef50_Q39C40 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   1.7  
UniRef50_Q2RVG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   1.7  
UniRef50_Q2GER3 Cluster: 5,10-methenyltetrahydrofolate synthetas...    35   1.7  
UniRef50_Q3DVF9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   1.7  
UniRef50_Q98N02 Cluster: Mll0364 protein; n=4; Rhizobiales|Rep: ...    35   2.3  
UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2; ...    35   2.3  
UniRef50_Q6J6A2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_Q1VME8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_A5IZ16 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_A5EXF0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    35   2.3  
UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_A4KQQ5 Cluster: 5-formyltetrahydroformate cycloligase; ...    35   2.3  
UniRef50_A1AXM1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_Q8TUZ6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_A7D5P9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    35   2.3  
UniRef50_Q82Y32 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   3.0  
UniRef50_Q7W1Z1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   3.0  
UniRef50_Q7MSV4 Cluster: Putative uncharacterized protein; n=1; ...    34   3.0  
UniRef50_Q6F1L6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   3.0  
UniRef50_Q4FR52 Cluster: Possible 5-formyltetrahydrofolate cyclo...    34   3.0  
UniRef50_Q44SK2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   3.0  
UniRef50_Q0IBL5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    34   3.0  
UniRef50_A5V9J0 Cluster: 5-formyltetrahydrofolate cyclo-ligase p...    34   3.0  
UniRef50_A3S249 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   3.0  
UniRef50_A1A037 Cluster: Putative uncharacterized protein; n=2; ...    34   3.0  
UniRef50_A0LR79 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   3.0  
UniRef50_UPI0000D56FA8 Cluster: PREDICTED: similar to CG14648-PA...    34   4.0  
UniRef50_O68985 Cluster: Putative uncharacterized protein; n=1; ...    34   4.0  
UniRef50_Q1LS15 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    34   4.0  
UniRef50_Q380R7 Cluster: ENSANGP00000026266; n=2; Culicidae|Rep:...    34   4.0  
UniRef50_Q17J32 Cluster: Putative uncharacterized protein; n=2; ...    34   4.0  
UniRef50_P47487 Cluster: Uncharacterized protein MG245; n=2; Myc...    34   4.0  
UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    33   5.2  
UniRef50_A6DB91 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   5.2  
UniRef50_A3HW78 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   5.2  
UniRef50_Q5UXE1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   5.2  
UniRef50_UPI0000DB6C87 Cluster: PREDICTED: similar to CG14648-PA...    33   6.9  
UniRef50_Q8F6Q4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   6.9  
UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate cyclo...    33   6.9  
UniRef50_Q47T07 Cluster: Putative uncharacterized protein; n=1; ...    33   6.9  
UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f...    33   6.9  
UniRef50_A1HAT0 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l...    33   6.9  
UniRef50_UPI0000EB2908 Cluster: UPI0000EB2908 related cluster; n...    33   9.2  
UniRef50_P88949 Cluster: ORF 58; n=3; Human herpesvirus 8|Rep: O...    33   9.2  
UniRef50_Q9KEL6 Cluster: BH0836 protein; n=1; Bacillus haloduran...    33   9.2  
UniRef50_Q30SA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ...    33   9.2  
UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r...    33   9.2  

>UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to
           5-formyltetrahydrofolate cyclo-ligase
           (5,10-methenyl-tetrahydrofolate synthetase)
           (Methenyl-THF synthetase) (MTHFS); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           5-formyltetrahydrofolate cyclo-ligase
           (5,10-methenyl-tetrahydrofolate synthetase)
           (Methenyl-THF synthetase) (MTHFS) - Tribolium castaneum
          Length = 197

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 40/87 (45%), Positives = 58/87 (66%), Gaps = 1/87 (1%)
 Frame = +3

Query: 249 RAQYAGGRMRMLHLET-GDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSR 425
           R +Y+   M M+ + +  D +T+P T  GI Q G  + R+DAL+TGGLD ++ PGV F+ 
Sbjct: 80  RYRYSKAGMEMVKIHSYQDWETLPVTSWGIKQPGLKEQREDALKTGGLDFVVVPGVGFTA 139

Query: 426 SGDRLGHGGGYYDKFITNLRLNPETAP 506
            G RLGHGGGYYD+++ +LR N +  P
Sbjct: 140 KGLRLGHGGGYYDRYMADLRKNQDVPP 166



 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 31/72 (43%), Positives = 50/72 (69%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  +R EI+ ++  LT+EEK+ QS+IV+EK++N   ++ S R++ Y+S +NEIDT P+++
Sbjct: 8   KEAVRREISERLKHLTSEEKQTQSKIVFEKLLNLPSFQKSKRVSTYLSIDNEIDTEPIVR 67

Query: 220 HIQARGAAAFVP 255
            I   G   FVP
Sbjct: 68  KIFETGKECFVP 79


>UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 161

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 37/71 (52%), Positives = 48/71 (67%), Gaps = 1/71 (1%)
 Frame = +3

Query: 255 QYAGGRMRMLHLET-GDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSG 431
           QY G +M M+ + +  D + +P+TK  I Q   D  R+DAL+TGGLDLII PG+ FS+ G
Sbjct: 43  QYIGPKMNMMKMSSMEDYEALPETKWKIKQPADDDVREDALKTGGLDLIIIPGLGFSKEG 102

Query: 432 DRLGHGGGYYD 464
            RLG G GYYD
Sbjct: 103 HRLGRGKGYYD 113


>UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep:
           CG11079-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 318

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 38/74 (51%), Positives = 51/74 (68%), Gaps = 2/74 (2%)
 Frame = +3

Query: 258 YAGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETG-GLDLIIAPGVAFSRSG 431
           Y G RM+M+ L   +E +++P TK  I Q    +AR+DA+  G G+DL I PGVAF+R G
Sbjct: 200 YEGSRMKMVRLRGMEEYESLPLTKWNIKQPDFKEAREDAMTNGHGIDLFIVPGVAFTRCG 259

Query: 432 DRLGHGGGYYDKFI 473
            R+GHG GYYDKF+
Sbjct: 260 ARMGHGMGYYDKFL 273



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/81 (32%), Positives = 42/81 (51%)
 Frame = +1

Query: 31  NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 210
           N  K  LR  +   +  +  E   RQSQ V  KV+    ++ + R+++Y+ST +E+DT  
Sbjct: 124 NTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTASELDTTA 183

Query: 211 LIKHIQARGAAAFVPSTPEGA 273
           L+  +       FVP T EG+
Sbjct: 184 LLSEMFRLEKMVFVP-TYEGS 203


>UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 205

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 36/74 (48%), Positives = 49/74 (66%), Gaps = 1/74 (1%)
 Frame = +3

Query: 255 QYAGGRMRMLHLET-GDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSG 431
           +Y G +M ML L +  D Q++P T   I Q   D  R++AL TGGLD+I+ PG+ FS++G
Sbjct: 83  RYIGHQMDMLRLHSLEDMQSLPLTPWNIHQPADDDIREEALNTGGLDVILVPGLGFSKNG 142

Query: 432 DRLGHGGGYYDKFI 473
            RLG G GYYD +I
Sbjct: 143 QRLGRGKGYYDNYI 156



 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 25/73 (34%), Positives = 46/73 (63%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           AK LLR +I  +I A++ E K+++S ++ EK++    YKSS RI++Y+S  +E+ T  ++
Sbjct: 10  AKKLLRRQIKKRILAMSEEAKRKESAMITEKLLAMEEYKSSHRISVYLSMPSEVSTFDIL 69

Query: 217 KHIQARGAAAFVP 255
           + I       ++P
Sbjct: 70  RDIFNSNKKCYIP 82



 Score = 33.1 bits (72), Expect = 6.9
 Identities = 11/30 (36%), Positives = 20/30 (66%)
 Frame = +2

Query: 509 IVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 598
           ++ +AF+ Q+ D+VP  E D  +D V+F +
Sbjct: 169 LIGLAFSTQMYDQVPVTENDMTLDHVVFCQ 198


>UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=16; Euteleostomi|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Homo sapiens (Human)
          Length = 203

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 35/87 (40%), Positives = 51/87 (58%), Gaps = 1/87 (1%)
 Frame = +3

Query: 249 RAQYAGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSR 425
           R ++    M M+ +E+ +E   +PKT   I Q G+   R++AL TGGLDLI  PG+ F +
Sbjct: 82  RYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVREEALSTGGLDLIFMPGLGFDK 141

Query: 426 SGDRLGHGGGYYDKFITNLRLNPETAP 506
            G+RLG G GYYD ++     + E  P
Sbjct: 142 HGNRLGRGKGYYDAYLKRCLQHQEVKP 168



 Score = 69.3 bits (162), Expect = 9e-11
 Identities = 32/81 (39%), Positives = 54/81 (66%)
 Frame = +1

Query: 13  MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 192
           M+    + AK  LR E+  ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1   MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60

Query: 193 EIDTAPLIKHIQARGAAAFVP 255
           EI+T  +IK I  RG   F+P
Sbjct: 61  EIETEEIIKDIFQRGKICFIP 81



 Score = 34.3 bits (75), Expect = 3.0
 Identities = 14/29 (48%), Positives = 21/29 (72%)
 Frame = +2

Query: 512 VAVAFNCQVVDEVPTNEQDQKVDEVIFAE 598
           +A+AF  Q+  +VP NE D KVDEV++ +
Sbjct: 171 LALAFKEQICLQVPVNENDMKVDEVLYED 199


>UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=12; Euteleostomi|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Oryctolagus cuniculus (Rabbit)
          Length = 201

 Score = 72.9 bits (171), Expect = 7e-12
 Identities = 34/76 (44%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
 Frame = +3

Query: 249 RAQYAGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSR 425
           R +     M M+ L + DE  ++PKT   I Q  +   R++AL TGGLDLI  PG+ F R
Sbjct: 82  RYRLQSNHMDMVKLASADEISSLPKTSWNIHQPSESDTREEALATGGLDLIFMPGLGFDR 141

Query: 426 SGDRLGHGGGYYDKFI 473
           +G+RLG G GYYD ++
Sbjct: 142 NGNRLGRGRGYYDTYL 157



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 27/73 (36%), Positives = 47/73 (64%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           AK  LR E+  ++ A++ EE+ R  +++ +KVI H  Y+ S RI++++S  +EI+T  +I
Sbjct: 9   AKRSLRAELKQRLRAISAEERLRCQRLLTQKVIAHRQYQKSQRISIFLSMPDEIETEEII 68

Query: 217 KHIQARGAAAFVP 255
           K I  +G   F+P
Sbjct: 69  KDIFQQGKVCFIP 81


>UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Culicidae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Aedes aegypti (Yellowfever mosquito)
          Length = 208

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 36/69 (52%), Positives = 46/69 (66%), Gaps = 2/69 (2%)
 Frame = +3

Query: 273 MRMLHL-ETGDEQTMPKTKHGISQHG-KDQARDDALETGGLDLIIAPGVAFSRSGDRLGH 446
           MRM+ + +  D   +P T   I Q    D +R+D L TG LD+II PGV F+RSG RLGH
Sbjct: 87  MRMVKINDMVDYDRLPTTSWNIKQPNFGDNSREDCLATG-LDMIILPGVGFTRSGHRLGH 145

Query: 447 GGGYYDKFI 473
           GGGYYD+F+
Sbjct: 146 GGGYYDRFL 154



 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 27/76 (35%), Positives = 46/76 (60%)
 Frame = +1

Query: 31  NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 210
           NPAK  LR ++   ++ +++  +  QS+I+  KV    +Y  S RI +Y+STE E++T P
Sbjct: 6   NPAKVALRQQLKTVMSNMSSTARITQSKIIANKVQQLPFYHDSQRICIYLSTEREVNTVP 65

Query: 211 LIKHIQARGAAAFVPS 258
           L++ +  R    FVP+
Sbjct: 66  LLQDMFHRSKEVFVPT 81


>UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Caenorhabditis|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Caenorhabditis
           elegans
          Length = 206

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 34/67 (50%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
 Frame = +3

Query: 312 MPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI-TNLRL 488
           +P T  GI Q           ETG LDLI+APGVAFS  G R GHG GYYD+F  T+ + 
Sbjct: 102 LPSTLWGIRQPEPKWKWQSYHETGPLDLILAPGVAFSPYGLRCGHGKGYYDRFFSTHHKH 161

Query: 489 NPETAPK 509
            PE +PK
Sbjct: 162 FPENSPK 168



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 29/87 (33%), Positives = 50/87 (57%)
 Frame = +1

Query: 13  MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 192
           MS IK    K+ LR  +   +  ++ EE +RQ++ V+EK+I   W++ S R+++Y+ST  
Sbjct: 1   MSAIKE--VKSELRQFMKTLLGKISKEETQRQTEAVFEKIIESKWFQESKRLSVYVSTSG 58

Query: 193 EIDTAPLIKHIQARGAAAFVPSTPEGA 273
           EI T  +I+     G   F+P   +G+
Sbjct: 59  EIQTDSIIQKALEMGKEVFIPQFTKGS 85


>UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 254

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 25/43 (58%), Positives = 34/43 (79%)
 Frame = +3

Query: 348 KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           ++QA D+     GLDLI+APGVAF ++G RLGHG GYYD+++T
Sbjct: 151 REQALDETTGGDGLDLILAPGVAFDQTGGRLGHGKGYYDRYLT 193


>UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
           5-formyltetrahydrofolate cyclo-ligase precursor -
           Moorella thermoacetica (strain ATCC 39073)
          Length = 202

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 22/38 (57%), Positives = 32/38 (84%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           ++ G +DL++ PGVAF R+G+RLG+GGGYYD+F+  LR
Sbjct: 112 VDPGDIDLVLVPGVAFDRAGNRLGYGGGYYDRFLATLR 149


>UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 214

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 29/70 (41%), Positives = 46/70 (65%), Gaps = 2/70 (2%)
 Frame = +3

Query: 273 MRMLHLET-GDEQTM-PKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGH 446
           M M+H+ + GD   + P+ K+ + +  +     +   T GLDL+I PG+AF++SG RLGH
Sbjct: 94  MSMIHVPSLGDVHNLEPQGKYRLLEPTEGT---EVFNTAGLDLLILPGMAFTKSGRRLGH 150

Query: 447 GGGYYDKFIT 476
           G G+YD+F+T
Sbjct: 151 GAGFYDEFLT 160


>UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;
           n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
           Mus musculus
          Length = 86

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 25/64 (39%), Positives = 46/64 (71%)
 Frame = +1

Query: 13  MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 192
           M+ +  N AK  LR E+  ++ AL+ EE+ RQS ++ +KVI H+ Y++S RI++++S ++
Sbjct: 1   MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD 60

Query: 193 EIDT 204
           E++T
Sbjct: 61  EVET 64


>UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 216

 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 23/47 (48%), Positives = 34/47 (72%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 506
           DAL++G LDLI+ PGVAF++  +RLGHG G+YD+++   +   E  P
Sbjct: 128 DALDSGDLDLILMPGVAFNQQRERLGHGAGFYDEYLYTYKTKWEHLP 174



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/74 (28%), Positives = 45/74 (60%), Gaps = 1/74 (1%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 213
           AK LLR +I  K+A ++ E   +QSQ + ++++    +K++ ++AL+M+  + E+ T P+
Sbjct: 10  AKKLLRVKIKHKLATISQESLSQQSQEILDRLVQSPIFKNAQKVALFMNMPDLEVKTLPI 69

Query: 214 IKHIQARGAAAFVP 255
           I+    +    ++P
Sbjct: 70  IQECYNQKKEVYLP 83


>UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pirellula sp.|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Rhodopirellula baltica
          Length = 205

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 3/76 (3%)
 Frame = +3

Query: 267 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARD---DALETGGLDLIIAPGVAFSRSGDR 437
           G + +  LE+ DE  + +  + I +  +++ RD   + + +  LD+++ PGVAF R G R
Sbjct: 89  GELELFRLESMDE--LAEGMYEILEP-REELRDLVPNRVRSSDLDVVLVPGVAFDRHGGR 145

Query: 438 LGHGGGYYDKFITNLR 485
           +GHG GYYDK + N+R
Sbjct: 146 VGHGKGYYDKLLGNVR 161


>UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Symbiobacterium thermophilum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Symbiobacterium
           thermophilum
          Length = 197

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 26/67 (38%), Positives = 39/67 (58%)
 Frame = +3

Query: 282 LHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYY 461
           LH   G  + + +  +GI +   D  ++D      +DL++ PGVAF R G RLG+GGGYY
Sbjct: 87  LHRWDGTPEQLVRGAYGIPEPRPDLPQEDPR---AVDLVVVPGVAFDRRGRRLGYGGGYY 143

Query: 462 DKFITNL 482
           D+ +  L
Sbjct: 144 DRLLPQL 150


>UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Halothermothrix orenii H 168|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Halothermothrix
           orenii H 168
          Length = 193

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 20/33 (60%), Positives = 27/33 (81%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           GLD++I PG+ FSR G R+G+GGGYYD+F+  L
Sbjct: 116 GLDIVIVPGIVFSRDGYRIGYGGGYYDRFLVKL 148


>UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Porphyromonas gingivalis|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Porphyromonas gingivalis (Bacteroides gingivalis)
          Length = 185

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 28/67 (41%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
 Frame = +3

Query: 294 TGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           TG+     +  +GI++   D A   A+    LDL++ PGVAF R G R+G G GYYD+F+
Sbjct: 87  TGEADLEAEGAYGIAEPTADAAT--AILPSSLDLLLVPGVAFDRKGSRMGRGKGYYDRFL 144

Query: 474 --TNLRL 488
             T +RL
Sbjct: 145 PATQVRL 151


>UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 196

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 27/75 (36%), Positives = 42/75 (56%)
 Frame = +3

Query: 270 RMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHG 449
           R+ +  +E  + + +P    GI +   ++AR   LE   ++ ++ PGVAF R G RLGHG
Sbjct: 86  RLELYEVEDPERELVPGV-WGIPEPNPERARRVGLEE--VEFVLVPGVAFDRRGGRLGHG 142

Query: 450 GGYYDKFITNLRLNP 494
            GYYD+ +   R  P
Sbjct: 143 AGYYDRLLGGARRLP 157


>UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Desulfotomaculum reducens MI-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Desulfotomaculum
           reducens MI-1
          Length = 191

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 25/58 (43%), Positives = 35/58 (60%)
 Frame = +3

Query: 327 HGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +GI +   +  R   +E   LDLI+ PG  F   G+R+G+GGGYYD+FI  LR +  T
Sbjct: 100 YGILEPAPENLRP--VEVQELDLIVVPGTVFDHQGNRMGYGGGYYDRFIPRLRKDAVT 155


>UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2;
           Ostreococcus|Rep: Predicted methyltransferase -
           Ostreococcus tauri
          Length = 515

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 33/75 (44%), Positives = 42/75 (56%), Gaps = 8/75 (10%)
 Frame = +3

Query: 273 MRMLHLETGDEQTMPKTKHGISQHGKDQA----RDDALE----TGGLDLIIAPGVAFSRS 428
           MRML +E   E  + +  +G+ +    +A    R DALE     G LD+II PG AF   
Sbjct: 71  MRMLEIED-PETDVERGAYGLPEPRATRADGSRRVDALEDIETVGALDVIIVPGFAFGED 129

Query: 429 GDRLGHGGGYYDKFI 473
           G RLG GGGYYD F+
Sbjct: 130 GRRLGRGGGYYDAFL 144


>UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus halodurans|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Bacillus halodurans
          Length = 186

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 25/69 (36%), Positives = 39/69 (56%)
 Frame = +3

Query: 267 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGH 446
           G  +M   E      +  T  G+ +    + R   ++   LDL++ PGVAF + G+RLG+
Sbjct: 80  GTTQMTFYEIHSFSVLEDTFFGLREPKPSECRQ--IDGQELDLLLVPGVAFDQKGNRLGY 137

Query: 447 GGGYYDKFI 473
           GGGYYD+F+
Sbjct: 138 GGGYYDRFL 146


>UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Lactobacillus reuteri|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Lactobacillus reuteri F275
          Length = 184

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 27/72 (37%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
 Frame = +3

Query: 276 RMLHLETGDEQTMPKTKHGISQ--HGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHG 449
           +M  +E  ++    +T  GI +   GK  + D+      +DL++ PGVAF+ SG+RLG G
Sbjct: 83  QMEFVELNEDTDFDETSFGILEPHDGKVYSPDE------IDLMVVPGVAFTASGNRLGFG 136

Query: 450 GGYYDKFITNLR 485
           GGYYD+++ N +
Sbjct: 137 GGYYDRYLKNYK 148



 Score = 33.9 bits (74), Expect = 4.0
 Identities = 19/75 (25%), Positives = 36/75 (48%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           +K  LR    A++  L    +  + + +   + +   +  +  IA+ +S   EIDTAP+I
Sbjct: 4   SKKELRQAYIARLQQLDLNTRLYEERKLASLLYDQPEWTGAKTIAVTLSQSFEIDTAPII 63

Query: 217 KHIQARGAAAFVPST 261
            H + +G    +P T
Sbjct: 64  LHARHKGQQIVIPRT 78


>UniRef50_A6RBY2 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 262

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 22/39 (56%), Positives = 27/39 (69%)
 Frame = +3

Query: 375 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           E+ GLDL++ PG+AF     RLGHG GYYD FI  L+ N
Sbjct: 163 ESSGLDLVVMPGLAFDEQLQRLGHGKGYYDHFINRLKGN 201


>UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=3; Saccharomycetales|Rep:
           5,10-methenyltetrahydrofolate synthetase - Pichia
           stipitis (Yeast)
          Length = 207

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 20/36 (55%), Positives = 28/36 (77%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           DA++ G LD++I PGV FS +  R+GHG G+YD+FI
Sbjct: 125 DAMDEGDLDVVIVPGVVFSTTKQRMGHGAGFYDEFI 160



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMS-TE 189
           MS +K   AK  LR +I   + A++ E  + QS  +++K++ H  ++ +++IALYM+  +
Sbjct: 1   MSSLKQ--AKTQLRRQIKESLRAISQESLQTQSNDIHKKLLGHPVFQKATKIALYMNMPD 58

Query: 190 NEIDTAPLIKHIQARGAAAFVP 255
           +E+ T  +I      G   ++P
Sbjct: 59  SEVKTDAIIHSCYQMGKQVYLP 80


>UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Carboxydothermus hydrogenoformans
           Z-2901|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Carboxydothermus hydrogenoformans (strain
           Z-2901 / DSM 6008)
          Length = 192

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 23/46 (50%), Positives = 34/46 (73%)
 Frame = +3

Query: 348 KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           K++AR  A E   +DL++ PGVAF   G+RLG+G G+YD+F+ NL+
Sbjct: 106 KEEARTIA-EPEVIDLVLVPGVAFDLKGNRLGYGAGFYDRFLPNLQ 150


>UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 175

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 20/28 (71%), Positives = 26/28 (92%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           DLII PGVAFS+ G+RLG+GGG+YD+F+
Sbjct: 113 DLIIVPGVAFSKKGERLGYGGGFYDRFL 140


>UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=4; Staphylococcus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
          Length = 183

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 19/38 (50%), Positives = 29/38 (76%)
 Frame = +3

Query: 378 TGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           T  +DL++ PGVAF + G R+G+GGGYYD+F++  + N
Sbjct: 111 TNKMDLVVVPGVAFDKLGYRIGYGGGYYDRFLSQHKCN 148



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 19/71 (26%), Positives = 34/71 (47%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           LR  I  K+ +   E+K    + + +K+     Y+ ++ I   +S  +E++T P+I H  
Sbjct: 6   LRRNIIKKMKSYDKEQKYLADEWLAKKLYQSEAYRKANTIGFVLSMPHEVNTYPIITHSL 65

Query: 229 ARGAAAFVPST 261
                 FVP T
Sbjct: 66  NNNKKIFVPET 76


>UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=12; Staphylococcus aureus|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Staphylococcus
           aureus (strain Newman)
          Length = 197

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 20/34 (58%), Positives = 25/34 (73%)
 Frame = +3

Query: 378 TGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           T  LDLI+ PGV F   G R+G+GGGYYD+F+ N
Sbjct: 129 TNNLDLIVVPGVGFQDDGYRIGYGGGYYDRFLAN 162



 Score = 33.5 bits (73), Expect = 5.2
 Identities = 20/81 (24%), Positives = 36/81 (44%)
 Frame = +1

Query: 13  MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 192
           ++ +  N  K  +R  I  K+      EK++    +  +      YK ++ IAL +S  +
Sbjct: 12  LNKVGDNVTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANAIALVLSFNH 71

Query: 193 EIDTAPLIKHIQARGAAAFVP 255
           E+DT  +I+         FVP
Sbjct: 72  EVDTFSIIEQALMDHKRIFVP 92


>UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Desulfotalea psychrophila|Rep:
           Probable 5-formyltetrahydrofolate cyclo-ligase -
           Desulfotalea psychrophila
          Length = 191

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 20/50 (40%), Positives = 33/50 (66%)
 Frame = +3

Query: 327 HGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           +GISQ       +++L    +D++I PG  F R G R+G+GGG+YD+F++
Sbjct: 99  YGISQPSSTYMEENSLLAEEIDVVICPGSLFDRRGGRMGYGGGFYDRFLS 148



 Score = 35.5 bits (78), Expect = 1.3
 Identities = 20/72 (27%), Positives = 38/72 (52%)
 Frame = +1

Query: 46  LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 225
           LLR E+  K   L++ E+  QS+   +K+ +  +   +  + +Y+S   E++T  L+  +
Sbjct: 4   LLRREVLIKRKNLSDAERFEQSKRAVQKLSD--FLAEAQTVFVYLSYNGEVETFELVDKL 61

Query: 226 QARGAAAFVPST 261
            ARG    +P T
Sbjct: 62  LARGFRVTIPWT 73


>UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Desulfovibrio vulgaris subsp.
           vulgaris|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - Desulfovibrio vulgaris (strain
           Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 283

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 20/29 (68%), Positives = 25/29 (86%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           DL I PGVAF R G+RLG+GGGYYD+F++
Sbjct: 212 DLAIIPGVAFDRQGNRLGYGGGYYDRFLS 240



 Score = 39.5 bits (88), Expect = 0.080
 Identities = 19/73 (26%), Positives = 36/73 (49%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           AK  LR E+  +   L  EE +R   +    ++ H  + ++ ++ LY++  NE+DT  L+
Sbjct: 91  AKTALRREMLQRRRDLDREEAQRHGALAQAALLAHPAWVTARQVVLYVAVRNELDTDLLL 150

Query: 217 KHIQARGAAAFVP 255
           +     G    +P
Sbjct: 151 RTAWEAGKEVLLP 163


>UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Bacillus sp. SG-1|Rep: Possible
           5-formyltetrahydrofolate cyclo-ligase - Bacillus sp.
           SG-1
          Length = 187

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 20/31 (64%), Positives = 25/31 (80%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +DL+I PG+AF  SG RLG GGGYYD+F+ N
Sbjct: 117 IDLVIVPGLAFMNSGYRLGFGGGYYDRFLVN 147


>UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 similarity to human 5; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|P40099
           Saccharomyces cerevisiae YER183c FAU1 similarity to
           human 5 - Yarrowia lipolytica (Candida lipolytica)
          Length = 212

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/69 (42%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
 Frame = +3

Query: 273 MRMLHL-ETGDEQTM-PKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGH 446
           +RML + +  D Q + P+  + + +  KD    D LE+GGL LI+ PGVA +    RLGH
Sbjct: 98  LRMLEIVDFKDVQNLQPRGPYKLKEPTKDAK--DVLESGGLGLIVLPGVAMTPQCARLGH 155

Query: 447 GGGYYDKFI 473
           G G+YD +I
Sbjct: 156 GVGFYDAYI 164



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
 Frame = +1

Query: 34  PAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAP 210
           PAK  LR  IA ++A ++ +  ++QS      +   + YKS+  IA YM+ ++ E++T  
Sbjct: 4   PAKQQLRKLIAQRVADVSKDSIQKQSLATTAALRTLNEYKSAQNIAFYMNMDSGELETMD 63

Query: 211 LIKHIQARGAAAFVP 255
           +I++        F+P
Sbjct: 64  MIRNAFEDKKRVFLP 78


>UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Thermus thermophilus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
          Length = 184

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 19/33 (57%), Positives = 26/33 (78%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           LDL++ PG+AF R G RLGHG G+YD+F+  +R
Sbjct: 103 LDLVVVPGLAFDREGYRLGHGQGFYDRFLKEVR 135


>UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus salivarius subsp. salivarius
           UCC118|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Lactobacillus salivarius subsp. salivarius (strain
           UCC118)
          Length = 182

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 20/35 (57%), Positives = 29/35 (82%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           +DLII PG+AF+ +G RLG GGG+YDK++++ R N
Sbjct: 117 IDLIIVPGLAFAENGARLGFGGGFYDKYLSDYRGN 151



 Score = 35.1 bits (77), Expect = 1.7
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNE-EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           K   +N+I  K+  L+   EKK     +Y+++   + ++ +  +A+ +S + E+DT P+I
Sbjct: 6   KEFRKNQIQ-KLQKLSKTWEKKLDELNLYKELFKTTEWEKADNVAITLSEDFELDTFPII 64

Query: 217 KHIQARGAAAFVPST 261
              Q +     VP T
Sbjct: 65  STAQQQNKKVLVPKT 79


>UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate
           cyclo-ligase-related protein; n=1; Clostridium kluyveri
           DSM 555|Rep: 5-formyltetrahydrofolate
           cyclo-ligase-related protein - Clostridium kluyveri DSM
           555
          Length = 181

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 19/38 (50%), Positives = 28/38 (73%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +E   +D+   PG+AF +SG R+G+GGGYYD+F+  LR
Sbjct: 111 VEETSIDICYVPGLAFDKSGGRVGYGGGYYDRFLKKLR 148


>UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus sp. B14905|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Bacillus sp. B14905
          Length = 197

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 18/42 (42%), Positives = 30/42 (71%)
 Frame = +3

Query: 360 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           R + ++   +D+I+ PGV F R G R+G+GGGYYD+++ N +
Sbjct: 108 RCELVDANEMDIILVPGVVFDRLGYRIGYGGGYYDRYVLNYK 149



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 21/72 (29%), Positives = 40/72 (55%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LRN++   +A + +E  +RQS+ V ++V+   +   ++ I + +S + E+DT  LI+
Sbjct: 3   KTTLRNKVRETLAIMNDEVYRRQSKAVVKRVLQEPYIIEANTIGITISNQPEVDTILLIE 62

Query: 220 HIQARGAAAFVP 255
            +   G    VP
Sbjct: 63  ELWQLGKKVAVP 74


>UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Thermosinus carboxydivorans Nor1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Thermosinus
           carboxydivorans Nor1
          Length = 197

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 21/42 (50%), Positives = 28/42 (66%)
 Frame = +3

Query: 351 DQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           D A    ++   +DL+  PGVAF R G+RLG G GYYD+F+T
Sbjct: 110 DPACAKNIDPARIDLVFVPGVAFDREGNRLGMGAGYYDRFLT 151


>UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=3; Coxiella burnetii|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Coxiella burnetii
          Length = 197

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 26/64 (40%), Positives = 36/64 (56%)
 Frame = +3

Query: 318 KTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE 497
           K + GI +   D  R+  + T  LDLI  P VAF + G+RLG G GYYD+ +  L+ +  
Sbjct: 101 KNRFGIGE--PDPTRETPIATKELDLIFLPLVAFDKDGNRLGRGAGYYDRALAFLKDSNA 158

Query: 498 TAPK 509
             PK
Sbjct: 159 QKPK 162



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 22/73 (30%), Positives = 42/73 (57%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           +K  LR+++  +   L+ +EK + S+I+ +K++  S +KSS R+A Y+S + E+D    +
Sbjct: 6   SKKQLRDQLRQRRNELSFQEKNKASEIICKKIMGLSIFKSSERLAFYLSHDGEVDIRIAL 65

Query: 217 KHIQARGAAAFVP 255
                   A F+P
Sbjct: 66  SKALEVKKACFLP 78


>UniRef50_Q830J1 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Enterococcus faecalis|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Enterococcus faecalis (Streptococcus faecalis)
          Length = 180

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 22/58 (37%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
 Frame = +3

Query: 306 QTMPKTKHGISQHGKDQARDDALE--TGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           Q  P+T +  S  G ++    A E     +DL+I PG+ F+R+G R+G GGG+YD+++
Sbjct: 88  QVFPETVYDTSAFGVEEPPLTAAEITATAIDLLIVPGIVFNRAGYRIGFGGGFYDRYL 145


>UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-like
           protein; n=10; Magnoliophyta|Rep:
           5-formyltetrahydrofolate cyclo-ligase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 287

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
 Frame = +3

Query: 273 MRMLHLETGDEQTMPKTK----HGISQHGKDQARDDALETGG-LDLIIAPGVAFSRSGDR 437
           MRMLH+   ++             +   G D  R+D L+    +DL I PG+AF R G R
Sbjct: 105 MRMLHISHMEDLVANSMNILEPAPVDAQGND--REDVLQADEPIDLFILPGLAFDRCGRR 162

Query: 438 LGHGGGYYDKFI 473
           LG GGGYYD F+
Sbjct: 163 LGRGGGYYDTFL 174



 Score = 35.9 bits (79), Expect = 0.98
 Identities = 15/64 (23%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE--NEIDTAPL 213
           K ++R+ +   + A+    + +Q + + + V+   W+KS   +  Y+S +  NE+DT+ +
Sbjct: 18  KRVVRSTVRKSLKAMDPSLRTQQDEAIQKTVLEAPWFKSCKGLCAYISCKSLNEVDTSKI 77

Query: 214 IKHI 225
           +  I
Sbjct: 78  LSEI 81


>UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Magnetococcus sp. MC-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Magnetococcus
           sp. (strain MC-1)
          Length = 196

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 23/52 (44%), Positives = 33/52 (63%)
 Frame = +3

Query: 330 GISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           GI Q G D+A+   +E G +DL++ P V F   G RLG+GGG+YD+ +   R
Sbjct: 103 GIPQPGPDRAQ---IEPGAVDLMLVPLVGFDAQGGRLGYGGGFYDRTLAGQR 151



 Score = 41.9 bits (94), Expect = 0.015
 Identities = 21/78 (26%), Positives = 36/78 (46%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR  + A   AL    +   +      +++H+W   + R+ALY +   E+D APL+ 
Sbjct: 6   KEALRKTLLAWRGALDPAWRASANAAAVAHLLSHAWLGQAERVALYCAIRGELDPAPLLA 65

Query: 220 HIQARGAAAFVPSTPEGA 273
            +   G   ++P    GA
Sbjct: 66  PLWQMGKILYLPRLEAGA 83


>UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 233

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 21/34 (61%), Positives = 23/34 (67%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           GLDLI+ PG+AF  S  RLGHG GYYD F    R
Sbjct: 149 GLDLIVVPGLAFDESFGRLGHGKGYYDHFFMRCR 182


>UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Bacillus clausii KSM-K16|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Bacillus clausii
           (strain KSM-K16)
          Length = 187

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 39/56 (69%)
 Frame = +3

Query: 306 QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           + + + K+G+ +  +++A    +    L+LI+ PGVAF+++G RLG GGG+YD+F+
Sbjct: 93  EELVENKYGLFEPKQEEAC--LVRPDELELIVVPGVAFTKAGKRLGLGGGFYDRFL 146



 Score = 32.7 bits (71), Expect = 9.2
 Identities = 18/73 (24%), Positives = 38/73 (52%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           +K  +RN+++ ++  L     K++S  + + ++    +  ++ IAL +S   E++TAPLI
Sbjct: 3   SKQNIRNDVSKQLNMLPAHVYKQRSTRLADLLMQQDVWNQATTIALTVSRFPEVETAPLI 62

Query: 217 KHIQARGAAAFVP 255
               A      +P
Sbjct: 63  AGALAENKKVVLP 75


>UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Exiguobacterium sibiricum 255-15|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Exiguobacterium
           sibiricum 255-15
          Length = 182

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 24/54 (44%), Positives = 38/54 (70%)
 Frame = +3

Query: 318 KTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +TK GI +   DQA + +L +  +DL + PG AF+R+G R+G GGG+YD+ +T+
Sbjct: 92  ETKMGIREPD-DQANEQSLRS--VDLCLVPGRAFTRAGYRIGWGGGFYDRALTD 142


>UniRef50_Q03RP0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus brevis ATCC 367|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           brevis (strain ATCC 367 / JCM 1170)
          Length = 182

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
 Frame = +3

Query: 318 KTKHGISQHGKDQARDDAL-ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           +T    S  G  +  + A+      DL+I PG+ F+ SG+RLG GGGYYD+++       
Sbjct: 91  QTNFATSPFGLQEPTNGAIIAPATFDLLIVPGLVFAASGERLGFGGGYYDRYLVKTTGTK 150

Query: 495 ETAPK*LQWLLT 530
                  QW+ T
Sbjct: 151 VALALPAQWVAT 162



 Score = 34.7 bits (76), Expect = 2.3
 Identities = 17/74 (22%), Positives = 40/74 (54%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR +    + A+  ++++  ++ ++ ++ +   ++ +  +A  +S + E+ TAP+I 
Sbjct: 4   KKHLRQQTIQALMAMPADQRQHATRDLHHQLWSSLAWQQAKTVATTISGDFELATAPIID 63

Query: 220 HIQARGAAAFVPST 261
             QA G    VP+T
Sbjct: 64  RAQAEGKTIAVPTT 77


>UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium thermocellum ATCC 27405|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 191

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/64 (35%), Positives = 37/64 (57%)
 Frame = +3

Query: 294 TGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           T  E  +    +GI +  K+ +R   ++   +DL++ PGVAF   G R+G+G GYYD F+
Sbjct: 92  TNQEGCLKPGTYGILEPVKEFSRK--IDPKDIDLVVVPGVAFDVKGGRIGYGAGYYDIFL 149

Query: 474 TNLR 485
             +R
Sbjct: 150 REVR 153



 Score = 35.9 bits (79), Expect = 0.98
 Identities = 22/72 (30%), Positives = 36/72 (50%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR E       L+ EE   +S+++ EK+I+   + +S  +  YM  +NE+ T  LI+
Sbjct: 4   KRELRKEALNIRKGLSEEEIIEKSKLITEKLISLDGFYNSKCVMAYMDFKNEVMTRFLIE 63

Query: 220 HIQARGAAAFVP 255
           H    G    +P
Sbjct: 64  HCLNLGKIVALP 75


>UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Psychromonas ingrahamii (strain 37)
          Length = 196

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/65 (41%), Positives = 36/65 (55%)
 Frame = +3

Query: 279 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           +L LE   +  M   +HGI +   +Q   DA     LDLI  P VAF   G+R+G GGGY
Sbjct: 88  LLFLEYTTKTEMVLNQHGIFEPKLNQL--DACPMKELDLIFTPLVAFDTQGNRIGMGGGY 145

Query: 459 YDKFI 473
           YD+ +
Sbjct: 146 YDRML 150



 Score = 32.7 bits (71), Expect = 9.2
 Identities = 13/69 (18%), Positives = 38/69 (55%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           +R++I      L+  ++K+ +  ++ ++I HS  + + +I++ ++ + EIDT   ++   
Sbjct: 10  IRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCW 69

Query: 229 ARGAAAFVP 255
            +    ++P
Sbjct: 70  QKNKKIYLP 78


>UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=6; Trichocomaceae|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Aspergillus clavatus
          Length = 243

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 20/31 (64%), Positives = 24/31 (77%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           GLDLI+ PG+AF +   RLGHG GYYD F+T
Sbjct: 154 GLDLIVMPGMAFDQGFRRLGHGKGYYDHFLT 184


>UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=29; Streptococcus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Streptococcus pneumoniae
          Length = 179

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K+ LR ++  ++ A++ E+K+   Q + E+++ H +Y+ +  IA Y+S  +E  T  LI+
Sbjct: 2   KSELRKQVLHEMKAISQEQKQAIDQALTERLLQHPFYQEAKVIATYLSFSHEFQTQELIE 61

Query: 220 HIQARGAAAFVPST-PEG 270
                G    +P T P+G
Sbjct: 62  QALKDGKKVLIPKTYPKG 79



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 16/36 (44%), Positives = 27/36 (75%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           + ++   +DLI  PG+AF+  G R+G+GGGYYD+++
Sbjct: 106 EVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYL 141


>UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 186

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 21/62 (33%), Positives = 37/62 (59%)
 Frame = +3

Query: 300 DEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           ++  + + ++G+ + G+D      +    +DLI+ PG+ F R G RLG GGGYYD+++  
Sbjct: 96  EKSVLIRHRYGMLEPGEDCP---VVPREAIDLILVPGLCFDRLGYRLGQGGGYYDRYLAG 152

Query: 480 LR 485
            R
Sbjct: 153 YR 154



 Score = 36.3 bits (80), Expect = 0.74
 Identities = 19/72 (26%), Positives = 37/72 (51%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           KA LR  + A+++A++ EE++    I++ + +      ++ R+ L+     E DTA LI 
Sbjct: 10  KAALRRVVRARLSAMSPEEREESDGILFRRFLALPEVAAADRVLLFYGMGAEPDTARLIP 69

Query: 220 HIQARGAAAFVP 255
            +   G    +P
Sbjct: 70  VLLDMGKQVLLP 81


>UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium acetobutylicum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           acetobutylicum
          Length = 182

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/73 (34%), Positives = 42/73 (57%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           +K  LR  +  K  +L  + K  +  ++Y KVIN   YKS++ I +++S ++E+DT  +I
Sbjct: 4   SKKELRKNMVLKRDSLEPDLKSIKDNMIYNKVINSIQYKSANNIFVFVSYKSEVDTHNII 63

Query: 217 KHIQARGAAAFVP 255
           +   A G   FVP
Sbjct: 64  RTAIADGKKVFVP 76



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 16/37 (43%), Positives = 29/37 (78%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           +E   ++L++ PG+AF  SG R+G+GGG+YD++++ L
Sbjct: 112 IEPESIELLLVPGLAFDESGGRIGYGGGFYDRYMSLL 148


>UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=6; Clostridium|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Clostridium tetani
          Length = 183

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 17/33 (51%), Positives = 24/33 (72%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +D++  PG+AF   G RLG+GGG+YDKF   L+
Sbjct: 117 IDIVFTPGLAFDNKGGRLGYGGGFYDKFFKRLK 149


>UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Chlorobium phaeobacteroides BS1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           phaeobacteroides BS1
          Length = 194

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/79 (39%), Positives = 39/79 (49%)
 Frame = +3

Query: 264 GGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLG 443
           G  + M+    GDE T    + G  +   D    D L     D++I P VA  R G RLG
Sbjct: 85  GETLCMVPFNEGDEVT--DGRFGQPEPVSDNGCADVLP----DVVILPVVAVDREGRRLG 138

Query: 444 HGGGYYDKFITNLRLNPET 500
           +G GYYD+FI  LRL   T
Sbjct: 139 YGKGYYDRFIAGLRLQGAT 157



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAP 210
           +K  +R E   + A++ +EE +  S ++ E V     ++ +  + +Y+S     E+DTAP
Sbjct: 6   SKERIRRECRERRASMDSEEWRSASSLIAENVAGIQEFREARTVMMYLSMNERREVDTAP 65

Query: 211 LIKHIQARG-AAAFVPST 261
           LI    + G ++ +VP T
Sbjct: 66  LISLCASFGNSSLYVPVT 83


>UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Enterococcus faecium DO|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Enterococcus
           faecium DO
          Length = 180

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 16/31 (51%), Positives = 26/31 (83%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +DL+I PG+ ++R+G R+G GGGYYD+++ N
Sbjct: 117 IDLLIVPGIIYNRAGYRIGFGGGYYDRYLNN 147



 Score = 39.5 bits (88), Expect = 0.080
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           K  LR +   K+  L    KK++  Q +Y+++    ++KS+  I   +S E E+DT P+I
Sbjct: 5   KVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKSAKVIGTTLSNEFELDTQPVI 64

Query: 217 KHIQARGAAAFVPST 261
           +  +       VP T
Sbjct: 65  QRAEKEQKKIVVPKT 79


>UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=3; Clostridium perfringens|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Clostridium perfringens (strain SM101 / Type A)
          Length = 192

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 18/30 (60%), Positives = 26/30 (86%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           +DLII PG+AF   G+RLG+GGG+YD+F++
Sbjct: 119 VDLIIIPGLAFDLKGNRLGYGGGFYDRFLS 148


>UniRef50_Q03UF8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 177

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 22/54 (40%), Positives = 35/54 (64%)
 Frame = +3

Query: 303 EQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYD 464
           E  M K+K GI +  +D+ +   L+  G+DL++ PGVAFS    R+G+G G++D
Sbjct: 89  ESLMSKSKFGILEPTQDENQAQNLK--GIDLMVVPGVAFSEDNYRIGYGAGFFD 140


>UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Geobacillus|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Geobacillus kaustophilus
          Length = 190

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 17/28 (60%), Positives = 25/28 (89%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           DLII PGV F+++G R+G+GGGYYD+++
Sbjct: 120 DLIIVPGVCFAKTGYRIGYGGGYYDRYL 147


>UniRef50_Q1NVQ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; delta proteobacterium MLMS-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - delta
           proteobacterium MLMS-1
          Length = 199

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 19/41 (46%), Positives = 27/41 (65%)
 Frame = +3

Query: 351 DQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           D A    ++   LD+++ PG  F R G RLG+GGGYYD+F+
Sbjct: 110 DPAHCLPVDPRALDVVLVPGSVFDRRGGRLGYGGGYYDRFL 150


>UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 178

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 19/29 (65%), Positives = 24/29 (82%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           LDL+I PG+AF+ SG RLG G GYYD+F+
Sbjct: 114 LDLVIVPGLAFTVSGKRLGFGAGYYDRFL 142



 Score = 33.1 bits (72), Expect = 6.9
 Identities = 19/72 (26%), Positives = 38/72 (52%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K+ LR +  A +A     ++KR+ + +Y  +     ++S+  IA+ +S E E++T+P+I 
Sbjct: 4   KSELRIQQKAALARENLMKRKREEEQLYALLFQTPEWQSADSIAVTLSMEFELNTSPIII 63

Query: 220 HIQARGAAAFVP 255
               +     VP
Sbjct: 64  KAWEKSKRVLVP 75


>UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Clostridiaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Alkaliphilus metalliredigens QYMF
          Length = 192

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 18/32 (56%), Positives = 24/32 (75%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LD II PG+AF   G R+G+GGGYYD+F+  +
Sbjct: 117 LDFIIVPGLAFDSQGYRIGYGGGYYDRFLPKI 148



 Score = 38.3 bits (85), Expect = 0.18
 Identities = 20/72 (27%), Positives = 37/72 (51%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR ++ A+   L++   + +SQ V   + N S YK +  + LY+S   E+ T  +I+
Sbjct: 2   KNTLRKQLLAQREILSSVHMETKSQQVRSSLFNFSPYKKAQHVMLYVSFGKEVITRGIIQ 61

Query: 220 HIQARGAAAFVP 255
            +  +    F+P
Sbjct: 62  DLLDQNKRVFIP 73


>UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pelotomaculum thermopropionicum SI|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Pelotomaculum
           thermopropionicum SI
          Length = 203

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 17/34 (50%), Positives = 26/34 (76%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           ++  GLDL++ PG+AF   G RLG+G G+YD+F+
Sbjct: 125 VDPAGLDLVVVPGLAFDLKGYRLGYGSGFYDRFL 158


>UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 234

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 9/76 (11%)
 Frame = +3

Query: 273 MRMLHL-ETGDEQTMPKTKHGISQHGKDQA------RDDALETGG--LDLIIAPGVAFSR 425
           MRML L  T D +  P  + GI   G ++       R+DA+      +DLI+ PGVAF  
Sbjct: 106 MRMLRLYSTQDLENCPLDRWGIVDPGVERRDMDKSFREDAMSPKAPPMDLILIPGVAFDE 165

Query: 426 SGDRLGHGGGYYDKFI 473
             +RLG G  YYD+F+
Sbjct: 166 ECNRLGRGKAYYDRFL 181


>UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=11; Bacillus cereus group|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Bacillus anthracis
          Length = 192

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 16/33 (48%), Positives = 27/33 (81%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +DL I PGVA++  G+R+G+GGGYYD+++ + +
Sbjct: 119 IDLQIVPGVAYTERGERIGYGGGYYDRYLVHYK 151



 Score = 34.7 bits (76), Expect = 2.3
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           K  LR +I   + +L+ E     S QIV+       W ++ + I + +S ENE++T P+I
Sbjct: 5   KLRLRKQIIEHMNSLSKERYTTLSEQIVFSLYEQKEWAEAKT-IGITLSMENEVNTYPII 63

Query: 217 KHIQARGAAAFVP 255
           +     G    VP
Sbjct: 64  EKAWKEGKRVVVP 76


>UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus delbrueckii subsp. bulgaricus ATCC
           BAA-365|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC
           BAA-365)
          Length = 190

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/53 (43%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
 Frame = +3

Query: 318 KTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSG-DRLGHGGGYYDKFI 473
           +TK G+ +  +++  D+AL     DL+  PG+AFS +G  R+G GGGYYD+F+
Sbjct: 100 QTKFGVWELAEEKEADNAL-----DLLFVPGLAFSPAGKSRIGFGGGYYDRFL 147


>UniRef50_A6EDM4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pedobacter sp. BAL39|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Pedobacter sp. BAL39
          Length = 191

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 18/35 (51%), Positives = 28/35 (80%)
 Frame = +3

Query: 369 ALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           AL TG +D++I P +AF  SG+R+G+G G+YD+F+
Sbjct: 111 ALHTGDVDMVIIPLLAFDMSGNRVGYGKGFYDRFL 145


>UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           precursor; n=1; Bacillus coagulans 36D1|Rep:
           5-formyltetrahydrofolate cyclo-ligase precursor -
           Bacillus coagulans 36D1
          Length = 191

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 17/34 (50%), Positives = 25/34 (73%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +E   +DL+I PG+ F + G R+G GGGYYD+F+
Sbjct: 112 IEKQAIDLLIVPGLVFDKKGFRIGFGGGYYDRFL 145


>UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Desulfuromonadales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Geobacter lovleyi SZ
          Length = 197

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 22/41 (53%), Positives = 28/41 (68%)
 Frame = +3

Query: 363 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           D ALET   DLI+ PGVAF   G R+G G GYYD+ ++ L+
Sbjct: 108 DHALETA--DLIVVPGVAFDLQGHRIGFGKGYYDRCLSQLQ 146


>UniRef50_Q8Y7E7 Cluster: Lmo1336 protein; n=13; Listeria|Rep:
           Lmo1336 protein - Listeria monocytogenes
          Length = 179

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 17/33 (51%), Positives = 27/33 (81%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +DL+I PGVAF++   R+G GGG+YD+F+T+ +
Sbjct: 117 IDLLIVPGVAFNKDHYRIGFGGGFYDRFLTDFQ 149


>UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Fusobacterium nucleatum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Fusobacterium
           nucleatum subsp. nucleatum
          Length = 181

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/61 (39%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
 Frame = +3

Query: 300 DEQTM----PKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           D++TM     K ++ +S  G  +   +  + G +D+II PGVAF R  +R+G G GYYD+
Sbjct: 79  DKETMIVIEDKNQYIVSPFGNKEPDGEEYK-GSIDVIITPGVAFDRDKNRVGFGRGYYDR 137

Query: 468 F 470
           F
Sbjct: 138 F 138


>UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Desulfitobacterium hafniense|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 194

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/53 (45%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
 Frame = +3

Query: 330 GISQHGKDQARD-DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           GI +  K +  + D LE  G   I  PG AF   G+RLG+GGGYYD+F   +R
Sbjct: 102 GIREPKKQELTEVDPLEIDG---IFVPGAAFDGQGNRLGYGGGYYDRFFERVR 151



 Score = 37.5 bits (83), Expect = 0.32
 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K LLR  + +  +ALT EE+  +SQ +   V     ++ +  I L+M+  +E++T  L +
Sbjct: 5   KRLLREHVLSLRSALTPEERASKSQRIRAIVTQTREFQEAGTIMLFMNFRDEVETTELAQ 64

Query: 220 HIQARGAAAFVP-STPEG 270
            +   G    +P   P+G
Sbjct: 65  KVLDLGKRLVLPRCAPKG 82



 Score = 36.7 bits (81), Expect = 0.56
 Identities = 15/37 (40%), Positives = 24/37 (64%)
 Frame = +2

Query: 479 FEAQSRNSSEIVAVAFNCQVVDEVPTNEQDQKVDEVI 589
           F  + R  +  +A+AF+CQ+VD +P    D+KVD +I
Sbjct: 146 FFERVREGTPKIALAFHCQIVDRIPVEVYDKKVDMLI 182


>UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium beijerinckii NCIMB 8052|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           beijerinckii NCIMB 8052
          Length = 196

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 18/36 (50%), Positives = 26/36 (72%)
 Frame = +3

Query: 363 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKF 470
           D  ++   LDLII PGVAF + G R+G+G G+YD++
Sbjct: 112 DPYIDPNELDLIIVPGVAFDKRGGRVGYGAGFYDRY 147



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 23/74 (31%), Positives = 37/74 (50%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K +LR EI  K   +   EK++  + + E V +  +YK +  I +Y+S + EI+T   IK
Sbjct: 7   KKILRKEILDKRKKIDVTEKEKMDERILETVYSSEYYKLAKNIFVYISFDTEINTRDFIK 66

Query: 220 HIQARGAAAFVPST 261
                    +VP T
Sbjct: 67  ESLNNNKRIYVPRT 80


>UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Blastopirellula marina DSM 3645|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Blastopirellula
           marina DSM 3645
          Length = 197

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 21/53 (39%), Positives = 32/53 (60%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK*LQWLLTVKLST 545
           +DL I PGVAF   G+RLG+G GY+D+ ++ +R    T     +  LT ++ T
Sbjct: 122 IDLAILPGVAFDLHGNRLGYGKGYFDRLLSEMRPQAVTCALAFECQLTAQIPT 174


>UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1; n=2; Saccharomycetales|Rep:
           Similar to sp|P40099 Saccharomyces cerevisiae YER183c
           FAU1 - Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 229

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 23/58 (39%), Positives = 32/58 (55%)
 Frame = +3

Query: 315 PKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL 488
           PK K+ + +   +  +   L    LD I+ PGVAF+    RLGHG GYYD F +  +L
Sbjct: 123 PKGKYNLKEPDIEDEKLSPLPPM-LDAILVPGVAFTSGCSRLGHGAGYYDDFFSRYKL 179


>UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC
           14580|Rep: YqgN - Bacillus licheniformis (strain DSM 13
           / ATCC 14580)
          Length = 190

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 15/38 (39%), Positives = 27/38 (71%)
 Frame = +3

Query: 360 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           + + +E   +D I+ PG+ + R G R+G+GGGYYD+++
Sbjct: 107 KTERMEPEDIDFILVPGICYDRRGYRIGYGGGYYDRYL 144



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/72 (26%), Positives = 39/72 (54%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR+E+  ++A +  +E   +++ ++ K+     +K +S IAL +S   E+ T P+I+
Sbjct: 2   KRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIE 61

Query: 220 HIQARGAAAFVP 255
             +  G    +P
Sbjct: 62  QARLEGKTVCIP 73


>UniRef50_Q2JU73 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Synechococcus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
           bacteriumYellowstone A-Prime)
          Length = 210

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 19/37 (51%), Positives = 26/37 (70%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           ++ G  DLI+ P +A  R G RLG+GGGYYD+F+  L
Sbjct: 127 IDPGKADLILVPALACDRWGRRLGYGGGYYDRFLAAL 163


>UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 194

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 16/27 (59%), Positives = 23/27 (85%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           L+I PGV F R+G+R+G+GGGYYD ++
Sbjct: 119 LVIVPGVVFDRAGNRIGYGGGYYDSYL 145


>UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=25; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Enterobacter sp. 638
          Length = 198

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 27/74 (36%), Positives = 39/74 (52%)
 Frame = +3

Query: 258 YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDR 437
           ++ G +  LH     E  + + K  I++   D    D L    LD++I P VAF R G R
Sbjct: 87  FSPGNLLFLHYHPHSELVVNRLK--ITEPKLDVR--DVLPLNELDVLITPLVAFDRYGQR 142

Query: 438 LGHGGGYYDKFITN 479
           LG GGG+YD+ + N
Sbjct: 143 LGMGGGFYDRTLQN 156



 Score = 35.1 bits (77), Expect = 1.7
 Identities = 20/82 (24%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  MSPIKPNPA-KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 189
           M+ +   PA +  +R  I  +   LT +++   +Q    +++ +S    +  +AL++S +
Sbjct: 1   MTQLSEVPASRQEIRQFIRKQRRTLTPDQQAHFAQQASARMMAYSPVVMAHTVALFLSFD 60

Query: 190 NEIDTAPLIKHIQARGAAAFVP 255
            E+DT PLI+ +   G   ++P
Sbjct: 61  GELDTQPLIEQLWRAGKKVYLP 82


>UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Sagittula stellata E-37|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Sagittula stellata E-37
          Length = 136

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 19/37 (51%), Positives = 27/37 (72%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +++I P VAFSRSG RLG+GGG+YD+ +  +R    T
Sbjct: 64  EILIVPLVAFSRSGGRLGYGGGFYDRTLERMRAKRPT 100


>UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Cenarchaeum symbiosum|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Cenarchaeum symbiosum
          Length = 173

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 22/51 (43%), Positives = 30/51 (58%)
 Frame = +3

Query: 354 QARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 506
           + R+D  E    D+II P V  +R G RLG+G GYYD+F+  L + P   P
Sbjct: 93  EPRNDCEECIDPDVIIVPAVGTARDGSRLGYGRGYYDRFLAGLDI-PSIVP 142


>UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=6; Bacteroides|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Bacteroides
           thetaiotaomicron
          Length = 196

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 27/67 (40%), Positives = 35/67 (52%)
 Frame = +3

Query: 282 LHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYY 461
           L L TG E     T +GI +   +   D A     +D I  PGVAF R G+RLG G GYY
Sbjct: 84  LRLYTGPEDMATGT-YGIEEPVGETFTDYA----DIDFIAVPGVAFDRKGNRLGRGKGYY 138

Query: 462 DKFITNL 482
           D+ +  +
Sbjct: 139 DRLLPRI 145


>UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Lactobacillus|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Lactobacillus gasseri (strain ATCC 33323
           / DSM 20243)
          Length = 195

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 26/68 (38%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
 Frame = +3

Query: 276 RMLHLETGDEQT-MPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRS-GDRLGHG 449
           R +     D+ T + KTK G+ ++   +A    +    LDLII PG+A+      RLG G
Sbjct: 94  RKMEFTLYDKNTILVKTKFGVLENHDSEA----IVNNNLDLIIVPGLAYGLDRNSRLGFG 149

Query: 450 GGYYDKFI 473
           GGYYD+F+
Sbjct: 150 GGYYDRFL 157



 Score = 34.7 bits (76), Expect = 2.3
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKK-RQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 213
           +K  LR     K+    N ++K  + +I+ EK++  S    +  I + +S   E++TAP+
Sbjct: 15  SKKELRKLQIKKLTEFANSKQKLSEDKILKEKLLRSSLLTKAESIGISVSMPIEVNTAPI 74

Query: 214 IKHIQARGAAAFVP 255
           I  +   G   ++P
Sbjct: 75  IASLWKMGKRVYIP 88


>UniRef50_Q8DK86 Cluster: Tll0980 protein; n=1; Synechococcus
           elongatus|Rep: Tll0980 protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 190

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/71 (32%), Positives = 36/71 (50%)
 Frame = +3

Query: 267 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGH 446
           GR    H   G E T+ +  +G+ Q   D      ++  G+DL + P VA  R G RLG+
Sbjct: 80  GRNLQWHCFDGKEDTLQQGPYGLWQPSPDAP---PIDPAGVDLCLIPAVACDRRGYRLGY 136

Query: 447 GGGYYDKFITN 479
           G G++D+   +
Sbjct: 137 GAGFFDRLFAH 147


>UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Clostridium difficile|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           difficile (strain 630)
          Length = 189

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 18/42 (42%), Positives = 28/42 (66%)
 Frame = +3

Query: 360 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +   ++   LD++I P VA+     RLG+GGG+YD+F+ NLR
Sbjct: 107 KSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLR 148


>UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Shewanella baltica|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Shewanella baltica OS195
          Length = 235

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/40 (47%), Positives = 27/40 (67%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 506
           LD++I P VAF   G+R+G GGGYYD+ + N +L  +  P
Sbjct: 162 LDVVITPLVAFDLMGNRMGMGGGYYDRTLANWQLKGKPLP 201


>UniRef50_Q4D2J6 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 307

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 19/33 (57%), Positives = 23/33 (69%)
 Frame = +3

Query: 375 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           E  G  L++APGV F   G RLG GGGYYD+F+
Sbjct: 213 ENPGWMLVLAPGVLFDSIGGRLGKGGGYYDRFL 245


>UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Treponema denticola|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Treponema denticola
          Length = 229

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 17/30 (56%), Positives = 23/30 (76%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LI+ PG AFS+ G+R+G GGG+YD+F   L
Sbjct: 153 LILVPGRAFSKKGERMGRGGGFYDRFFEKL 182


>UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus sakei subsp. sakei 23K|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           sakei subsp. sakei (strain 23K)
          Length = 180

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 18/34 (52%), Positives = 25/34 (73%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           DL+I PGV FS  G R+G GGGYYD+++   ++N
Sbjct: 116 DLMIVPGVVFSLDGWRVGFGGGYYDRYLAAHQMN 149


>UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=10; Gammaproteobacteria|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Aeromonas salmonicida (strain A449)
          Length = 202

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/63 (38%), Positives = 35/63 (55%)
 Frame = +3

Query: 279 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           +L L       M + ++GI++   D ++   +    LDLI  P VAF   G+RLG GGGY
Sbjct: 93  LLFLRYTATSPMTRNRYGIAEPELDMSQ--VVPHSTLDLICTPLVAFDAEGNRLGMGGGY 150

Query: 459 YDK 467
           YD+
Sbjct: 151 YDR 153



 Score = 35.1 bits (77), Expect = 1.7
 Identities = 18/69 (26%), Positives = 37/69 (53%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           LR  I  +  +L+  E++  +Q +  +   HS   ++ RIALY++ + E++  P I  + 
Sbjct: 15  LRQLIRLRRKSLSQAEQQEAAQQLVAQFKQHSEILAARRIALYLANDGELNPLPAIHWLW 74

Query: 229 ARGAAAFVP 255
           A+    ++P
Sbjct: 75  AQQKEVYLP 83


>UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Halorhodospira halophila SL1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Halorhodospira
           halophila (strain DSM 244 / SL1)
           (Ectothiorhodospirahalophila (strain DSM 244 / SL1))
          Length = 203

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/41 (51%), Positives = 26/41 (63%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK 509
           LDL++AP VAF  +G RLG GGG+YD     LR  P   P+
Sbjct: 118 LDLVLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPR 158


>UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 singleton; n=1; Kluyveromyces
           lactis|Rep: Similarities with sp|P40099 Saccharomyces
           cerevisiae YER183c FAU1 singleton - Kluyveromyces lactis
           (Yeast) (Candida sphaerica)
          Length = 291

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 19/38 (50%), Positives = 28/38 (73%), Gaps = 1/38 (2%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAF-SRSGDRLGHGGGYYDKFIT 476
           + L T  L++I+ PGVAF  ++G R+GHG GYYD +I+
Sbjct: 206 EPLPTPALEVILMPGVAFCKKNGARMGHGAGYYDDYIS 243


>UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; gamma proteobacterium HTCC2207|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           gamma proteobacterium HTCC2207
          Length = 195

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/54 (46%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
 Frame = +3

Query: 309 TMPKTKHGISQHGKDQARDDALETG-GLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           T+ K + GI +    Q R  A+     LDLI+ P VAF R+G+RLG GGG+YD+
Sbjct: 94  TLHKNRFGILE---PQFRSTAITPPWSLDLILLPLVAFDRAGNRLGMGGGFYDR 144



 Score = 33.9 bits (74), Expect = 4.0
 Identities = 15/69 (21%), Positives = 36/69 (52%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           +R+ I  K  AL   +++  S+ + + +    +++ + RI +Y++ + EID + ++    
Sbjct: 6   IRSNIREKRRALNPSQQRTASEQLAKLLCRQDFFQRAKRIGIYLANDGEIDPSAIVTAAF 65

Query: 229 ARGAAAFVP 255
               A F+P
Sbjct: 66  RAKKACFLP 74


>UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Desulfuromonas acetoxidans DSM 684|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Desulfuromonas
           acetoxidans DSM 684
          Length = 184

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 17/27 (62%), Positives = 22/27 (81%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDL++ PGVAF R G RLG+G G+YD+
Sbjct: 113 LDLVVVPGVAFGRCGSRLGYGKGFYDQ 139


>UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Alcanivorax borkumensis SK2|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 193

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 20/36 (55%), Positives = 24/36 (66%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           LD+II P VAF  +G RLG GGGYYD+ +  L   P
Sbjct: 120 LDVIILPAVAFDEAGYRLGMGGGYYDRTLEQLTRYP 155


>UniRef50_Q08SB2 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=2; Cystobacterineae|Rep: 5,10-methenyltetrahydrofolate
           synthetase - Stigmatella aurantiaca DW4/3-1
          Length = 245

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 17/33 (51%), Positives = 22/33 (66%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYD 464
           D +    +DL + PG+ F+R G RLG GGGYYD
Sbjct: 157 DLVPVDQIDLFVVPGLGFTRDGKRLGRGGGYYD 189


>UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1;
           Buchnera aphidicola (Schizaphis graminum)|Rep:
           Uncharacterized protein BUsg_396 - Buchnera aphidicola
           subsp. Schizaphis graminum
          Length = 199

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/38 (55%), Positives = 25/38 (65%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           D +    LDLII P VAF   G RLG GGG+YD+F+ N
Sbjct: 117 DIILESDLDLIIVPLVAFDCRGVRLGMGGGFYDQFLKN 154


>UniRef50_A6G5C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Plesiocystis pacifica SIR-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Plesiocystis
           pacifica SIR-1
          Length = 214

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
 Frame = +3

Query: 264 GGRMRMLHL-ETGDEQTMPKTKHGI---SQHGKDQARDDALETGGLDLIIAPGVAFSRSG 431
           G RM    L E  D + + + K G+   ++ G+        E  G+DLI+ PG+AFS  G
Sbjct: 86  GPRMVFWELREPADLEALERRKMGLREPAERGRSSPAPGPAE--GVDLILVPGLAFSPGG 143

Query: 432 DRLGHGGGYYDK 467
            RLG G G+YD+
Sbjct: 144 LRLGFGAGHYDR 155


>UniRef50_A4CIN4 Cluster: Putative uncharacterized protein; n=1;
           Robiginitalea biformata HTCC2501|Rep: Putative
           uncharacterized protein - Robiginitalea biformata
           HTCC2501
          Length = 186

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
 Frame = +3

Query: 309 TMPKTKHGISQHGKDQARD-DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           T P+T+   S  G  +    + +    LD++  P +AF   G R+G+GGGYYD+F+ + R
Sbjct: 88  TTPETRFITSPWGIPEPEGAEEVPPESLDVVFIPLLAFDAGGHRVGYGGGYYDRFLQHCR 147


>UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Marinobacter aquaeolei (strain ATCC
           700491 / DSM 11845 / VT8)(Marinobacter
           hydrocarbonoclasticus (strain DSM 11845))
          Length = 211

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/41 (46%), Positives = 25/41 (60%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK 509
           LD ++ P V F  +G RLG GGG+YD+     R+ P  APK
Sbjct: 134 LDAVLFPLVGFDETGGRLGMGGGFYDRTFAFSRIRPGMAPK 174


>UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Saccharomyces cerevisiae|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 211

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 18/39 (46%), Positives = 27/39 (69%), Gaps = 1/39 (2%)
 Frame = +3

Query: 375 ETGGLDLIIAPGVAFS-RSGDRLGHGGGYYDKFITNLRL 488
           E+  LD+++ PGVAF  ++G R+GHG GYYD F    ++
Sbjct: 128 ESDILDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKI 166



 Score = 34.7 bits (76), Expect = 2.3
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE-NEIDTAPLI 216
           K LLR +I   I AL  +    +S  + + V +     +S R+A YMS +  E+ T  +I
Sbjct: 4   KQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEII 63

Query: 217 KHIQARGAAAFVP 255
           K++   G   F+P
Sbjct: 64  KNLFQDGQEVFLP 76


>UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Caulobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 214

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 18/32 (56%), Positives = 23/32 (71%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           DL++ P +AF R G RLG GGGYYD+ +  LR
Sbjct: 137 DLVVTPLLAFQRDGVRLGQGGGYYDRALAFLR 168


>UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Methylococcus capsulatus|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Methylococcus capsulatus
          Length = 221

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 16/52 (30%), Positives = 32/52 (61%)
 Frame = +1

Query: 100 KRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVP 255
           +R S ++  + I+  W   ++R+A Y+  + E+DT  L ++++ RG  AF+P
Sbjct: 45  RRTSLLIAGRCIDAGWLDGAARMAAYLPNDGEVDTTVLFEYLRERGRTAFIP 96



 Score = 39.9 bits (89), Expect = 0.060
 Identities = 17/27 (62%), Positives = 19/27 (70%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDL+  P VAF   G RLG GGGYYD+
Sbjct: 137 LDLVFVPLVAFDPRGHRLGMGGGYYDR 163


>UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus acidophilus|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           acidophilus
          Length = 187

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
 Frame = +3

Query: 336 SQHGKDQARDDALETGG-LDLIIAPGVAFSRSGD-RLGHGGGYYDKFITNLRLNPET 500
           S+ G ++  D + +    LDL+I PG+ F+     R+G GGGYYD+F+   + NP T
Sbjct: 99  SKFGVEEIADKSAKVNNELDLVIVPGLLFATDSHVRIGFGGGYYDRFLA--KYNPRT 153



 Score = 33.9 bits (74), Expect = 4.0
 Identities = 17/56 (30%), Positives = 30/56 (53%)
 Frame = +1

Query: 85  TNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 252
           T EEKK +  ++ EK++  +  K+S  I +  S   E+DT+ LI  +   G   ++
Sbjct: 19  TTEEKKIEDAVLLEKLMGTNLIKNSQTIGVTASMPFEVDTSELIARLWDLGKEVYL 74


>UniRef50_Q3A217 Cluster: Putative ligase; n=1; Pelobacter
           carbinolicus DSM 2380|Rep: Putative ligase - Pelobacter
           carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 195

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 16/34 (47%), Positives = 25/34 (73%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           + +  LDL++ PGVAF   G+RLG+G G+YD+ +
Sbjct: 108 IPSSALDLVLVPGVAFDLEGNRLGYGKGFYDRVL 141


>UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Chlorobium/Pelodictyon group|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           ferrooxidans DSM 13031
          Length = 207

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 18/34 (52%), Positives = 26/34 (76%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL 488
           LD+++ P +AF RSG RLG+G G+YD+F+  L L
Sbjct: 132 LDVVLIPLLAFDRSGYRLGYGKGFYDRFLHRLSL 165


>UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Rhodobacterales bacterium
           HTCC2654|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - Rhodobacterales bacterium HTCC2654
          Length = 182

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 20/38 (52%), Positives = 28/38 (73%), Gaps = 1/38 (2%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR-LNPETA 503
           ++I P VAF R+G+RLG+GGG+YD+ +  LR L P  A
Sbjct: 110 VLIVPLVAFDRAGNRLGYGGGFYDRTLAALRALRPTLA 147


>UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Leptospirillum sp. Group II UBA|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Leptospirillum
           sp. Group II UBA
          Length = 206

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 16/32 (50%), Positives = 22/32 (68%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           G+DL   PG+ F R G R+G+G GYYD+ + N
Sbjct: 130 GVDLFFLPGLGFDRRGGRIGYGRGYYDRLLRN 161


>UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Oenococcus oeni|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Oenococcus oeni ATCC BAA-1163
          Length = 182

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 15/31 (48%), Positives = 26/31 (83%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           ++L+I PG+AF++SG RLG G G+YD+++ +
Sbjct: 117 IELMIVPGLAFTKSGKRLGFGAGFYDRYLAD 147



 Score = 34.7 bits (76), Expect = 2.3
 Identities = 18/72 (25%), Positives = 37/72 (51%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR +   ++ +   ++KK QS ++Y+ +   + + +S  IA+ +S   E++T P++K
Sbjct: 7   KQKLRRQQKKRLDSYDPDDKKDQSILLYQALFESNDWLNSETIAVTLSLPLELNTKPIVK 66

Query: 220 HIQARGAAAFVP 255
                     VP
Sbjct: 67  QAWELDKRVLVP 78


>UniRef50_Q57W74 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 320

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 17/27 (62%), Positives = 21/27 (77%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           L + PGV F R+G RLG GGGYYD+F+
Sbjct: 230 LSLTPGVLFDRTGGRLGKGGGYYDRFL 256


>UniRef50_Q9P7W2 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Schizosaccharomyces pombe|Rep:
           Putative 5-formyltetrahydrofolate cyclo-ligase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 204

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/57 (40%), Positives = 33/57 (57%)
 Frame = +3

Query: 306 QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           +++   K GI++   +  +    ET   +LII PGVAF     RLGHG GYYD +I+
Sbjct: 95  ESLTINKWGIAEPNGESRKIMDDETD-CELIIVPGVAFDEKLSRLGHGKGYYDNYIS 150


>UniRef50_Q92HS7 Cluster: Similarity to 5-formyltetrahydrofolate
           cyclo-ligase [EC:6.3.3.2]; n=8; Rickettsia|Rep:
           Similarity to 5-formyltetrahydrofolate cyclo-ligase
           [EC:6.3.3.2] - Rickettsia conorii
          Length = 196

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 16/32 (50%), Positives = 26/32 (81%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +L+I PG+AFS+ G RLG+G G++D+++ N R
Sbjct: 133 ELVIIPGLAFSKEGYRLGYGQGHFDRYLNNNR 164


>UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep:
           All4825 protein - Anabaena sp. (strain PCC 7120)
          Length = 193

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
 Frame = +3

Query: 312 MPKTKHGISQHGKDQARDDA--LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +PK    I+ +G  +    A  ++   +DLI+ P VA +  G RLG+GGGYYD+ +++
Sbjct: 93  IPKDSLNINAYGIKEPDPQAPTIDPEEVDLILVPSVACNYQGYRLGYGGGYYDRLLSS 150


>UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Oceanobacillus iheyensis|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Oceanobacillus
           iheyensis
          Length = 186

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 17/38 (44%), Positives = 26/38 (68%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           LE   L L I PG+ F ++G R+G GGGYYD+ + +++
Sbjct: 112 LENELLGLCIVPGIVFDKNGYRIGFGGGYYDRILPSIQ 149


>UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 193

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 21/72 (29%), Positives = 37/72 (51%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  +RN    +  AL++EE    S+I+  K+ N   ++ +  +ALY S +NE+ T  L++
Sbjct: 6   KDFVRNSCIIRRQALSSEEVHSASRIIAAKLFNDDVWRRARSVALYSSIKNEVSTESLLR 65

Query: 220 HIQARGAAAFVP 255
                G    +P
Sbjct: 66  QAWQEGKQVLLP 77



 Score = 37.1 bits (82), Expect = 0.43
 Identities = 15/29 (51%), Positives = 20/29 (68%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           +LII P V  +  G RLG+G GYYDK ++
Sbjct: 123 ELIIVPAVGLTSFGARLGYGKGYYDKLLS 151


>UniRef50_A6UKG2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Rhizobiales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Sinorhizobium medicae WSM419
          Length = 239

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 17/31 (54%), Positives = 23/31 (74%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D++IAP V F  SG RLG+GGGYYD+ +  +
Sbjct: 165 DIVIAPVVGFDASGYRLGYGGGYYDRTLAGM 195


>UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Gammaproteobacteria|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Marinobacter algicola DG893
          Length = 216

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 19/41 (46%), Positives = 24/41 (58%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK 509
           LD ++ P V F   G RLG GGG+YD+     R+ P  APK
Sbjct: 135 LDAVLFPLVGFDGFGGRLGMGGGFYDRTFAFTRIRPRLAPK 175


>UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 198

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
 Frame = +3

Query: 252 AQYAGGRMRMLHLETGDEQTMPKTKH---GISQHGKDQARDDALETGGLDLIIAPGVAFS 422
           A   G RM M  +   D    P   H     +    D      +    LD+I+ P VAF 
Sbjct: 85  AAACGQRMCMRAVAADDASAAPFIAHPTRAFAATDIDSNHFPIVPAEALDMIVVPLVAFD 144

Query: 423 RSGDRLGHGGGYYDKFITNL 482
           ++G RLG+GGG YD+++  L
Sbjct: 145 QTGARLGYGGGCYDRYLPML 164


>UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2;
           Bacillus|Rep: Uncharacterized protein yqgN - Bacillus
           subtilis
          Length = 187

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 16/30 (53%), Positives = 24/30 (80%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 476
           +DL+I PGV F  +G R+G GGGYYD++++
Sbjct: 116 IDLMIVPGVCFDVNGFRVGFGGGYYDRYLS 145


>UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23;
           Enterobacteriaceae|Rep: Uncharacterized protein ygfA -
           Escherichia coli O157:H7
          Length = 182

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 19/38 (50%), Positives = 24/38 (63%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           D L    LD++I P VAF   G RLG GGG+YD+ + N
Sbjct: 103 DVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQN 140



 Score = 35.5 bits (78), Expect = 1.3
 Identities = 15/59 (25%), Positives = 33/59 (55%)
 Frame = +1

Query: 79  ALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVP 255
           ALT E+++   Q    +++ +     +  +A+++S + E+DT PLI+ +   G   ++P
Sbjct: 8   ALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLP 66


>UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1;
           Mycoplasma gallisepticum|Rep: Putative uncharacterized
           protein - Mycoplasma gallisepticum
          Length = 186

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 19/41 (46%), Positives = 26/41 (63%)
 Frame = +3

Query: 363 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           ++ L    LDL I P V ++ +  RLGHG GYYD+F  NL+
Sbjct: 109 NEQLLNNHLDLFIVPLVGYNSNQLRLGHGKGYYDRFFNNLK 149


>UniRef50_Q4ULB4 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
           n=1; Rickettsia felis|Rep: 5-Formyltetrahydrofolate
           cyclo-ligase - Rickettsia felis (Rickettsia azadi)
          Length = 144

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 15/30 (50%), Positives = 25/30 (83%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +L+I PG+AFS+ G RLG+G G++D+++ N
Sbjct: 114 ELVITPGLAFSKDGYRLGYGKGHFDRYLNN 143


>UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetase,
           putative; n=1; Treponema pallidum|Rep:
           5,10-methenyltetrahydrofolate synthetase, putative -
           Treponema pallidum
          Length = 225

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 16/30 (53%), Positives = 23/30 (76%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LI+ P +AFS +G RLG GGG+YD+F+  +
Sbjct: 139 LIVVPALAFSTNGARLGRGGGHYDRFLARI 168


>UniRef50_Q11X92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 193

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 28/84 (33%), Positives = 45/84 (53%)
 Frame = +3

Query: 222 HPSQRGCGLRAQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLII 401
           HP  + C   +  A   + +LH     E T    K  I +  +  A ++  ET  +DLI+
Sbjct: 70  HPEIKLC--TSILAENNIDLLHTHITPETTYLPNKWNIPEPVERNAVNE--ET--IDLIL 123

Query: 402 APGVAFSRSGDRLGHGGGYYDKFI 473
            P VAF  +G+R+G+G G+YD+F+
Sbjct: 124 LPLVAFDATGNRVGYGKGFYDRFL 147


>UniRef50_Q03B49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus casei ATCC 334|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           casei (strain ATCC 334)
          Length = 186

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 18/33 (54%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGD-RLGHGGGYYDKFITNLR 485
           DLI+ PG+ FS +   R+G GGGYYD+F+T  R
Sbjct: 115 DLILVPGIGFSLADKYRIGFGGGYYDRFLTTYR 147


>UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Anaeromyxobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Anaeromyxobacter sp. Fw109-5
          Length = 205

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 17/26 (65%), Positives = 20/26 (76%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYD 464
           +D ++ PGVAFS  G RLG GGGYYD
Sbjct: 130 VDCVLMPGVAFSPDGHRLGRGGGYYD 155


>UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 249

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 16/27 (59%), Positives = 22/27 (81%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           L+I PGVAF R   R+G+GGG+YD+F+
Sbjct: 182 LMIMPGVAFDRQNHRVGYGGGFYDRFL 208


>UniRef50_Q7NMK6 Cluster: Glr0759 protein; n=1; Gloeobacter
           violaceus|Rep: Glr0759 protein - Gloeobacter violaceus
          Length = 184

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 17/41 (41%), Positives = 26/41 (63%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL 488
           +A++  G   ++ P VA  R G R+G+GGGYYD+F+    L
Sbjct: 101 EAVDPAGAAWVLVPVVACDRRGYRIGYGGGYYDRFLARYAL 141


>UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Sphingomonas sp. SKA58|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Sphingomonas sp.
           SKA58
          Length = 196

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 20/33 (60%), Positives = 25/33 (75%), Gaps = 3/33 (9%)
 Frame = +3

Query: 378 TGGL---DLIIAPGVAFSRSGDRLGHGGGYYDK 467
           TGG+   D+I+ P VAF RS +RLG GGGYYD+
Sbjct: 117 TGGVVSPDVIVTPLVAFDRSMNRLGQGGGYYDR 149


>UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=20; Rhodobacterales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Silicibacter sp. (strain TM1040)
          Length = 195

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 17/37 (45%), Positives = 26/37 (70%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +++I P VAF  +G+RLG+GGG+YD+ +  LR    T
Sbjct: 120 EILIVPLVAFDAAGNRLGYGGGFYDRTLDRLRAQRAT 156


>UniRef50_Q0AVU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Syntrophomonas wolfei subsp. wolfei
           str. Goettingen|Rep: 5-formyltetrahydrofolate
           cyclo-ligase family protein - Syntrophomonas wolfei
           subsp. wolfei (strain Goettingen)
          Length = 194

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 15/38 (39%), Positives = 25/38 (65%)
 Frame = +3

Query: 369 ALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           A+    +D+++ PG+ F   G RLG+G GYYD+F+  +
Sbjct: 112 AVPAAEIDVVLVPGLVFDTRGYRLGYGKGYYDRFLAGM 149


>UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=2; Parabacteroides|Rep: Putative
           5-formyltetrahydrofolate cyclo-ligase - Parabacteroides
           distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 184

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 16/32 (50%), Positives = 24/32 (75%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           +DLII PGVAF +  +R+G G G+YD+ ++ L
Sbjct: 117 IDLIIVPGVAFDKDKNRMGRGRGFYDRLLSTL 148


>UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Lactococcus lactis|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Lactococcus lactis subsp. cremoris (strain MG1363)
          Length = 177

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 19/60 (31%), Positives = 35/60 (58%)
 Frame = +3

Query: 300 DEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           D++ + ++K G+ +   D A +        D I+ PG+ ++  G R+G GGGYYD+++ N
Sbjct: 87  DKENLVRSKFGLLEPKSDLAIEP-------DFILVPGLIWNDEGHRIGFGGGYYDRYLAN 139


>UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Shewanella amazonensis SB2B|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
          Length = 228

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 19/32 (59%), Positives = 23/32 (71%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LD II P VAF  SG+RLG GGG+YD+ +  L
Sbjct: 153 LDAIITPLVAFDDSGNRLGMGGGFYDRTLAQL 184



 Score = 34.3 bits (75), Expect = 3.0
 Identities = 18/80 (22%), Positives = 39/80 (48%)
 Frame = +1

Query: 16  SPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENE 195
           S I  N +++ +R  + A    L+ + +   +    + ++       + R+ALY+  + E
Sbjct: 32  SGISANSSRSAIRKHVRALRRTLSGDVQTAAAIQAAQHLLTE--LADARRVALYLENDGE 89

Query: 196 IDTAPLIKHIQARGAAAFVP 255
           I T PLI+ +  +G   ++P
Sbjct: 90  ISTRPLIEALWQQGVEVYLP 109


>UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanocorpusculum labreanum Z|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 196

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 15/28 (53%), Positives = 22/28 (78%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKF 470
           +D+++ P V F R+G RLG+G GYYD+F
Sbjct: 115 IDVVLVPMVGFDRAGHRLGYGAGYYDRF 142


>UniRef50_UPI0000E87FAB Cluster: 5-formyltetrahydrofolate
           cyclo-ligase family protein; n=1; Methylophilales
           bacterium HTCC2181|Rep: 5-formyltetrahydrofolate
           cyclo-ligase family protein - Methylophilales bacterium
           HTCC2181
          Length = 188

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
 Frame = +3

Query: 306 QTMPKTKHGISQHGKDQARDDALETGG-LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           Q  P TK   + +   +  D   E G  +D++I P +AF   G R+G+G G+YD+F  +L
Sbjct: 89  QFSPHTKISQTHYNITEPIDPVWEEGNDIDMVITPLLAFDCKGYRVGYGKGFYDRFFASL 148


>UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
           n=1; Gluconobacter oxydans|Rep: 5-Formyltetrahydrofolate
           cyclo-ligase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 195

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 17/31 (54%), Positives = 23/31 (74%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           DL++ P +AF  SG RLG+GGGYYD+ +  L
Sbjct: 118 DLVLVPFLAFDASGYRLGYGGGYYDRTLAML 148


>UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Oceanobacter sp. RED65|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Oceanobacter sp. RED65
          Length = 239

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 20/41 (48%), Positives = 25/41 (60%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK 509
           LDL+  P VAF + G RLG GGG+YD+    LR +    PK
Sbjct: 164 LDLVFMPLVAFDQQGGRLGMGGGFYDRSFEFLRHSTLPKPK 204


>UniRef50_Q1IX36 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Deinococcus|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Deinococcus geothermalis (strain DSM
           11300)
          Length = 184

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 20/49 (40%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
 Frame = +3

Query: 333 ISQHGKDQARDDALETG--GLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +S+ G  Q   DA   G   +D ++ P +AF R G RLG+GGG+YD+ +
Sbjct: 93  VSRFGALQPPADAPRVGLEMVDAVLLPALAFDRRGVRLGYGGGFYDRLL 141


>UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=10; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Shewanella sp. (strain MR-7)
          Length = 228

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 24/83 (28%), Positives = 40/83 (48%)
 Frame = +3

Query: 258 YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDR 437
           +  G++  LH     +  M   + GI +   D      +E   +D+++ P VAF   G+R
Sbjct: 116 FNAGQLLFLHYHA--DSPMQPNQFGILEPKLDVRAVMPIEH--IDVVVTPLVAFDIKGNR 171

Query: 438 LGHGGGYYDKFITNLRLNPETAP 506
           +G GGGYYD+ + N     +  P
Sbjct: 172 MGMGGGYYDRTLANWHAKGKPLP 194



 Score = 35.9 bits (79), Expect = 0.98
 Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  MSP-IKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 189
           +SP + P  ++A LR +I     +L  E +   S     +++      ++  +ALY++ +
Sbjct: 30  LSPNLSPTLSRAELRKQIRLARRSLPIEVQTEASLAAGLRMLEKLSALNAQHVALYLTHD 89

Query: 190 NEIDTAPLIKHIQARGAAAFVP 255
            E+ TAPLI+ +  +G   ++P
Sbjct: 90  GELATAPLIEALWQQGIQTYLP 111


>UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pediococcus pentosaceus ATCC 25745|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Pediococcus
           pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 187

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 19/30 (63%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRS-GDRLGHGGGYYDKFI 473
           LDLII PG+A+  S G RLG GGGYYD+++
Sbjct: 114 LDLIIVPGLAYEVSNGYRLGFGGGYYDRYL 143



 Score = 38.7 bits (86), Expect = 0.14
 Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K + R     ++  +    K+ +  ++ E   +    K++ ++A+ MS   E+DTAP+I+
Sbjct: 3   KNIFRQTQIKRLNQIDITSKRAKEALILESFFDQHEVKNARKLAITMSHGFELDTAPIIQ 62

Query: 220 HIQARGAAAFVPST-PE 267
            +   G   +VP T PE
Sbjct: 63  RLIENGKCVYVPRTLPE 79


>UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16;
           Gammaproteobacteria|Rep: Uncharacterized protein HI0858
           - Haemophilus influenzae
          Length = 187

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           + L    LD++  P VAF + G+RLG GGG+YD+ + N
Sbjct: 114 NVLPLNELDILFTPLVAFDKKGNRLGMGGGFYDRTLQN 151


>UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2;
           Synechococcus elongatus|Rep: Putative uncharacterized
           protein - Synechococcus sp. (strain PCC 7942) (Anacystis
           nidulans R2)
          Length = 189

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 16/27 (59%), Positives = 21/27 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           +DL+I P VA  + G RLG+GGGYYD+
Sbjct: 116 IDLLIVPAVAVDKEGYRLGYGGGYYDR 142


>UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Parvibaculum lavamentivorans DS-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Parvibaculum
           lavamentivorans DS-1
          Length = 199

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 20/48 (41%), Positives = 29/48 (60%)
 Frame = +3

Query: 342 HGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           HG  + + DA      D+++ P +AF   G RLG+GGGYYD+ +  LR
Sbjct: 102 HGTREPQPDA-PVCRPDIVLVPLLAFDSVGRRLGYGGGYYDRTLAALR 148


>UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1;
           Dorea longicatena DSM 13814|Rep: Putative
           uncharacterized protein - Dorea longicatena DSM 13814
          Length = 174

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 17/36 (47%), Positives = 24/36 (66%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           D +  G   L+I PGVAF     R+G+GGG+YDK++
Sbjct: 89  DHIADGEDGLLIMPGVAFDEECHRIGYGGGFYDKYL 124


>UniRef50_A5GM63 Cluster: Putative uncharacterized protein
           SynWH7803_1602; n=2; Synechococcus|Rep: Putative
           uncharacterized protein SynWH7803_1602 - Synechococcus
           sp. (strain WH7803)
          Length = 197

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 16/27 (59%), Positives = 21/27 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDL++ P +A  R G RLG+GGGYYD+
Sbjct: 122 LDLLLVPALAVDRDGVRLGYGGGYYDR 148


>UniRef50_Q4QB50 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 449

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 17/28 (60%), Positives = 23/28 (82%), Gaps = 1/28 (3%)
 Frame = +3

Query: 393 LIIAPGVAFS-RSGDRLGHGGGYYDKFI 473
           L++APGV F  R+G RLG GGG+YD+F+
Sbjct: 310 LVLAPGVLFDVRTGSRLGKGGGFYDRFL 337


>UniRef50_Q89AD6 Cluster: Uncharacterized protein bbp_370; n=1;
           Buchnera aphidicola (Baizongia pistaciae)|Rep:
           Uncharacterized protein bbp_370 - Buchnera aphidicola
           subsp. Baizongia pistaciae
          Length = 195

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 18/49 (36%), Positives = 28/49 (57%)
 Frame = +3

Query: 360 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 506
           R + +++  LD++  P VAF   G RLG GGG+YD+ + N  +     P
Sbjct: 112 RKNFIQSDDLDIMFVPLVAFDEFGYRLGMGGGFYDRILINYDIKKSFFP 160


>UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Magnetospirillum magnetotacticum
           MS-1|Rep: COG0212: 5-formyltetrahydrofolate cyclo-ligase
           - Magnetospirillum magnetotacticum MS-1
          Length = 193

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 16/30 (53%), Positives = 24/30 (80%)
 Frame = +3

Query: 396 IIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           ++ P +AF R G RLG+GGGYYD+ +++LR
Sbjct: 120 LLVPLLAFDRRGFRLGYGGGYYDRTLSDLR 149


>UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=5; Vibrio|Rep: 5-formyltetrahydrofolate cyclo-ligase -
           Vibrio vulnificus
          Length = 199

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 18/27 (66%), Positives = 20/27 (74%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDLI  P VAF  +G RLG GGGYYD+
Sbjct: 121 LDLICTPLVAFDSTGQRLGMGGGYYDR 147



 Score = 32.7 bits (71), Expect = 9.2
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = +1

Query: 157 SSRIALYMSTENEIDTAPLIKHIQARGAAAFVP 255
           +  IALY+S + E+DT PLI+ +   G   ++P
Sbjct: 45  AQHIALYLSADGELDTKPLIEWLWELGKQVYLP 77


>UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=1; Pelodictyon luteolum DSM 273|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Pelodictyon luteolum (strain DSM 273) (Chlorobium
           luteolum (strain DSM273))
          Length = 213

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 16/33 (48%), Positives = 24/33 (72%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +D ++ P VA  RSG RLG+G G+YD+F+  L+
Sbjct: 129 IDAVVVPLVAVDRSGYRLGYGKGFYDRFLARLQ 161


>UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Salinibacter ruber DSM 13855|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Salinibacter
           ruber (strain DSM 13855)
          Length = 195

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 13/45 (28%), Positives = 26/45 (57%)
 Frame = +3

Query: 348 KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           ++    + +  G +D++  P +   + G R+GHG GYYD F+ ++
Sbjct: 113 REPKHTERVPPGAIDVVFVPALGVGQDGHRIGHGSGYYDAFLQSV 157


>UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium phytofermentans ISDg|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           phytofermentans ISDg
          Length = 190

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 14/26 (53%), Positives = 22/26 (84%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKF 470
           ++I PG+AF   G+R+G+GGGYYD++
Sbjct: 119 IMIVPGLAFDLMGNRIGYGGGYYDRY 144


>UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Actinobacillus succinogenes 130Z
          Length = 189

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 24/72 (33%), Positives = 38/72 (52%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           +A LR +I      LT  E+ R +Q V +K +N    + +  I LY+S + EI T PLI 
Sbjct: 8   RAQLRRQIRKTRQNLTALEQIRAAQTVTQKALNLIAQRHAEHIGLYLSFDGEISTRPLID 67

Query: 220 HIQARGAAAFVP 255
            + A+    ++P
Sbjct: 68  ALWAQRKNVYLP 79



 Score = 41.1 bits (92), Expect = 0.026
 Identities = 25/70 (35%), Positives = 36/70 (51%)
 Frame = +3

Query: 258 YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDR 437
           +  G M  LH  T + + MP   +G+          + L    LD+I  P VAF + G+R
Sbjct: 84  FCKGYMLFLHY-TPETELMP---NGLGIPEPRLNVKNILPINRLDIIFTPLVAFDKQGNR 139

Query: 438 LGHGGGYYDK 467
           LG GGG+YD+
Sbjct: 140 LGMGGGFYDR 149


>UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Clostridium cellulolyticum H10|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Clostridium
           cellulolyticum H10
          Length = 182

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 14/29 (48%), Positives = 23/29 (79%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +D++I PG AF  + +R+G+G GYYD+F+
Sbjct: 113 IDVVIVPGCAFDLNRNRMGYGAGYYDRFL 141


>UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Arthrobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Arthrobacter sp. (strain FB24)
          Length = 198

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 18/41 (43%), Positives = 22/41 (53%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 506
           G+  I  P  A   SG+R+G GGGYYDKF+  L       P
Sbjct: 120 GVAGIFVPATAVDLSGNRIGQGGGYYDKFLAGLEAAGRPVP 160


>UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanoregula
           boonei (strain 6A8)
          Length = 188

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 14/29 (48%), Positives = 23/29 (79%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +D+I+ P + F R+G R+G+G GYYD+F+
Sbjct: 116 VDVIVLPMLGFDRTGGRIGYGAGYYDRFL 144


>UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Geobacter|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Geobacter sulfurreducens
          Length = 187

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D+I+ PGVAF  +G R+G+G G+YD+ + +L
Sbjct: 115 DIIVVPGVAFDLAGHRIGYGKGFYDRALHHL 145



 Score = 32.7 bits (71), Expect = 9.2
 Identities = 16/73 (21%), Positives = 35/73 (47%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K +LR  + A   +L   E +  S+ +    +    ++++  IALY     E+DT+ +++
Sbjct: 3   KRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLR 62

Query: 220 HIQARGAAAFVPS 258
               +G    +P+
Sbjct: 63  LALDQGKTVLLPA 75


>UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=1; Chlorobium chlorochromatii CaD3|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Chlorobium chlorochromatii (strain CaD3)
          Length = 194

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
 Frame = +3

Query: 246 LRAQYAGGRMRMLHLETGDEQTM----PKTKHGISQHGKDQA-RDDALETGGLDLIIAPG 410
           L+A +A G+  ++ +  G E       P     I + G+ +  R    +   LD+++ P 
Sbjct: 68  LQALHAMGKKLLVPVVQGKELLSVCYEPSMPLRIGRFGQPEPERAIPADAAQLDVVVLPL 127

Query: 411 VAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +AF   G RLG+G GYYD+ +    L+  T
Sbjct: 128 LAFDEKGQRLGYGKGYYDRMLERFTLHHVT 157


>UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Bacillus sp. NRRL B-14911|Rep:
           Possible 5-formyltetrahydrofolate cyclo-ligase -
           Bacillus sp. NRRL B-14911
          Length = 175

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 17/40 (42%), Positives = 26/40 (65%)
 Frame = +3

Query: 354 QARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +A  + +E     L+I PG+A+   G RLG GGGYYD+++
Sbjct: 97  EALTEKIEPEEFGLMIVPGLAYCSGGLRLGFGGGYYDRWL 136


>UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Saccharophagus degradans 2-40|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Saccharophagus
           degradans (strain 2-40 / ATCC 43961 / DSM 17024)
          Length = 194

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 22/72 (30%), Positives = 37/72 (51%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LR  + AK  ALT  ++   S+ V   +   S Y+ ++ IA Y++ + E+D  P +K
Sbjct: 3   KDTLRQTMRAKRNALTPSQQAFASEQVATHLAQSSDYQQATHIAFYLACDGELDLTPALK 62

Query: 220 HIQARGAAAFVP 255
              A   A ++P
Sbjct: 63  QALADNKACYLP 74



 Score = 38.7 bits (86), Expect = 0.14
 Identities = 18/47 (38%), Positives = 29/47 (61%)
 Frame = +3

Query: 324 KHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYD 464
           ++GI++   D      ++   LDL++AP V F  + +RLG GGG+YD
Sbjct: 97  RYGIAEPSADNPE---IQPNRLDLVLAPLVGFDSNFNRLGMGGGFYD 140


>UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase protein; n=1; Spiroplasma citri|Rep:
           Putative 5-formyltetrahydrofolate cyclo-ligase protein -
           Spiroplasma citri
          Length = 183

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +D+++ P VAF ++  RLG+G GYYD+F+ N
Sbjct: 119 IDVLVVPIVAFDQNNFRLGYGKGYYDRFLKN 149



 Score = 35.9 bits (79), Expect = 0.98
 Identities = 18/72 (25%), Positives = 38/72 (52%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  +R E     + +++E ++++   +++    H   ++S  IALY S +NE++T  +IK
Sbjct: 6   KQEIRQEKLLARSKISSELRQQKETKIFDTFFQHPGVQNSKTIALYYSIKNEVNTLLIIK 65

Query: 220 HIQARGAAAFVP 255
            + A      +P
Sbjct: 66  RLFALKVNILLP 77


>UniRef50_Q0P948 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase family protein; n=5; Campylobacter|Rep:
           Putative 5-formyltetrahydrofolate cyclo-ligase family
           protein - Campylobacter jejuni
          Length = 208

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 24/83 (28%), Positives = 41/83 (49%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK*LQWLLTVKLST 545
           D+     +DL I P +   ++  R+GHG G+YD+F  NL   P      + ++ ++   +
Sbjct: 100 DSFFKAKIDLAIVPVIGVDKNLKRIGHGQGFYDRFFENLNYKPH-----IIFIQSIDALS 154

Query: 546 RCRLTNKTRKWTRLYSLNKYCSY 614
           +  LT K     +LY +N Y  Y
Sbjct: 155 QNNLTQKHDISGKLY-INPYKKY 176


>UniRef50_Q0BT60 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Acetobacteraceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Granulobacter bethesdensis (strain ATCC
           BAA-1260 / CGDNIH1)
          Length = 225

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 15/31 (48%), Positives = 24/31 (77%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           + ++ P +AF R+G+RLG+GGGYYD+ +  L
Sbjct: 150 ETVLVPLLAFDRTGNRLGYGGGYYDRTLAAL 180


>UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; marine gamma proteobacterium
           HTCC2143|Rep: 5-formyltetrahydrofolate cyclo-ligase
           family protein - marine gamma proteobacterium HTCC2143
          Length = 197

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 18/36 (50%), Positives = 21/36 (58%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           L L+  P V F R G RLG GGG+YD+   N R  P
Sbjct: 119 LGLVFLPLVGFDRQGGRLGMGGGFYDRTFANTRSAP 154


>UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanoculleus marisnigri JR1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanoculleus
           marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 203

 Score = 41.1 bits (92), Expect = 0.026
 Identities = 14/31 (45%), Positives = 23/31 (74%)
 Frame = +3

Query: 381 GGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           G ++ ++ P +AF   G+RLG+G GYYD+F+
Sbjct: 126 GDVEAVVIPMLAFDAEGNRLGYGAGYYDRFL 156


>UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Corynebacterium|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Corynebacterium glutamicum
           (Brevibacterium flavum)
          Length = 190

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 21/46 (45%), Positives = 29/46 (63%)
 Frame = +3

Query: 330 GISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           GI + G  +   +AL     DL+IAP +A + SG RLG GGG+YD+
Sbjct: 101 GIQEPGGTRLGPEALNF--CDLVIAPALACTPSGIRLGKGGGFYDR 144


>UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate
           cycloligase family; n=2; Candidatus Blochmannia|Rep:
           Ligase;5-formyltetrahydrofolate cycloligase family -
           Blochmannia floridanus
          Length = 195

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 18/34 (52%), Positives = 22/34 (64%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           D +    LD+I  P VAF   G+RLG GGG+YDK
Sbjct: 112 DLISLDKLDIIFIPLVAFDDHGNRLGMGGGFYDK 145



 Score = 37.5 bits (83), Expect = 0.32
 Identities = 20/75 (26%), Positives = 39/75 (52%)
 Frame = +1

Query: 31  NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 210
           N  K  +R+ I +   +L   E+ + +Q++  K+IN      ++ I +Y+S + EI T  
Sbjct: 2   NLNKKAIRSYIRSLRQSLNYSEQYKSAQLITNKIINLDCIHKATHIGIYISFDGEIYTDL 61

Query: 211 LIKHIQARGAAAFVP 255
           LIK + +     ++P
Sbjct: 62  LIKFLLSMKKKIYIP 76


>UniRef50_Q46JY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Prochlorococcus marinus|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Prochlorococcus
           marinus (strain NATL2A)
          Length = 198

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = +3

Query: 360 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           R DA+    + ++  P +A  + G RLG+GGGY+D+
Sbjct: 112 RKDAINPNDISILFVPAIAIDQEGYRLGYGGGYFDR 147


>UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1;
           Neptuniibacter caesariensis|Rep: Putative
           uncharacterized protein - Neptuniibacter caesariensis
          Length = 194

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 16/27 (59%), Positives = 21/27 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDL++ P VAF   G+R+G GGGYYD+
Sbjct: 119 LDLVLLPLVAFDPKGNRMGMGGGYYDR 145



 Score = 36.7 bits (81), Expect = 0.56
 Identities = 18/69 (26%), Positives = 34/69 (49%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           LR +I +   +LT  ++   +Q +   +     ++ +  IA+Y+  + EID  PLIK   
Sbjct: 7   LRKQIRSLRRSLTPSQQNTAAQALLRNMRTRQDFRRAKSIAMYLPNDGEIDPTPLIKLCW 66

Query: 229 ARGAAAFVP 255
             G   ++P
Sbjct: 67  KLGKEVYLP 75


>UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Candidatus Pelagibacter ubique|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Candidatus
           Pelagibacter ubique HTCC1002
          Length = 182

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 16/31 (51%), Positives = 24/31 (77%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D+++ P VAF ++ +RLG+GGGYYD+ I  L
Sbjct: 111 DVLLIPLVAFDKNLNRLGYGGGYYDRLIEKL 141


>UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Methylobacterium extorquens PA1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methylobacterium
           extorquens PA1
          Length = 262

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 21/49 (42%), Positives = 27/49 (55%)
 Frame = +3

Query: 345 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           G  + RDD        LI+ P  AF R+G R+G+G GYYD+ I  L  N
Sbjct: 173 GLSEPRDDLPPLDPTALIV-PLAAFDRAGQRIGYGAGYYDQAIERLSKN 220



 Score = 33.1 bits (72), Expect = 6.9
 Identities = 23/85 (27%), Positives = 36/85 (42%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           KA LR E  ++  AL+ E +K  S    E +        +  +  +    +EID  PLI+
Sbjct: 78  KASLRAEALSRRDALSPEARKAGSLRAAETIAAIPELAEAPLVGAFWPIRSEIDPRPLIE 137

Query: 220 HIQARGAAAFVPSTPEGA*GCYTWR 294
            + ARG    +P   +       WR
Sbjct: 138 RLFARGQRVALPKVTKQGLVFREWR 162


>UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus gnavus ATCC 29149|Rep: Putative
           uncharacterized protein - Ruminococcus gnavus ATCC 29149
          Length = 179

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +3

Query: 363 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D  LE   L L++ PGV+F  +G R+G+GGG+YD ++  +
Sbjct: 102 DCCLEKSDL-LMLVPGVSFDPAGRRIGYGGGFYDTYLQKM 140


>UniRef50_A2C833 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=6; Cyanobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Prochlorococcus marinus (strain MIT 9303)
          Length = 189

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 15/37 (40%), Positives = 26/37 (70%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           L+   + L++ P +A  + G RLG+GGG++D+F +NL
Sbjct: 110 LDADAIGLLLIPALAMDQRGIRLGYGGGFFDRFRSNL 146


>UniRef50_A1B1U2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Paracoccus denitrificans PD1222|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Paracoccus
           denitrificans (strain Pd 1222)
          Length = 194

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 15/32 (46%), Positives = 23/32 (71%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +++I P   F R+G RLG+GGG+YD+ +  LR
Sbjct: 106 EVLIVPLAGFDRAGHRLGYGGGFYDRTLAGLR 137


>UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 187

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 16/42 (38%), Positives = 27/42 (64%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           D      LD+I+ P V  +  G RLG+G G+YD+F++N +++
Sbjct: 109 DCETENNLDVILVPTVGITPKGIRLGYGHGFYDRFLSNHKIS 150


>UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 214

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           DLI+ P +A S  G RLG GGG+YD+ +T+
Sbjct: 139 DLIVIPALAASADGTRLGQGGGWYDRALTH 168


>UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Putative
           uncharacterized protein - Lentisphaera araneosa HTCC2155
          Length = 181

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 15/33 (45%), Positives = 21/33 (63%)
 Frame = +3

Query: 375 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           E   +D    P +AF R G+RLG GGG+YD+ +
Sbjct: 103 ELPAIDFCFIPALAFDRRGNRLGRGGGFYDRLL 135


>UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Prosthecochloris vibrioformis DSM 265|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
           vibrioformis DSM 265
          Length = 200

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LD ++ P VA  R G RLG G GYYD+F++ L
Sbjct: 118 LDAVLLPLVAVDRCGRRLGFGKGYYDRFLSRL 149


>UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=17; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Alteromonas macleodii 'Deep ecotype'
          Length = 229

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 22/71 (30%), Positives = 34/71 (47%)
 Frame = +3

Query: 279 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           +L L       + K K+ I +          + T   D+I+ P V F  +G+RLG GGGY
Sbjct: 109 LLFLSYTQHTALVKNKYNIEEPAL--VCPSVIPTSQCDVILMPLVGFDTNGNRLGMGGGY 166

Query: 459 YDKFITNLRLN 491
           YD+ +   + N
Sbjct: 167 YDRTLAFTQRN 177


>UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 194

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 20/57 (35%), Positives = 34/57 (59%)
 Frame = +3

Query: 297 GDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           G +  +P  + G+ +   ++   +A+ T   D+++ PG+A S SG RLG GGG YD+
Sbjct: 95  GPDHLVP-ARRGLLEPDAERLGPEAIGTA--DVVLTPGLAVSPSGVRLGRGGGCYDR 148


>UniRef50_UPI000050F91E Cluster: COG0212: 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Brevibacterium linens BL2|Rep:
           COG0212: 5-formyltetrahydrofolate cyclo-ligase -
           Brevibacterium linens BL2
          Length = 224

 Score = 39.9 bits (89), Expect = 0.060
 Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
 Frame = +3

Query: 267 GRMRMLHLETGDEQTM-PKTKHGISQHGKDQARDDALETG-GLDLIIAPGVAFSRSGDRL 440
           G   M    TG   T+ P+ K GI +          L      DLI  P + F   G RL
Sbjct: 85  GHALMFGAVTGSMSTLEPRGKWGIREPSPSLTASALLAAEVAPDLIFVPALGFGPGGARL 144

Query: 441 GHGGGYYDK 467
           G+GGG+YD+
Sbjct: 145 GNGGGFYDR 153


>UniRef50_Q88WQ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Lactobacillus plantarum|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
           plantarum
          Length = 188

 Score = 39.9 bits (89), Expect = 0.060
 Identities = 18/74 (24%), Positives = 41/74 (55%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K   R +   +++ +T  +++RQ+Q +  ++     ++++  IA+ +S++ E+ T PLI+
Sbjct: 3   KKAFRKQQLGRLSQMTPADRQRQNQALQTQLFASPTWQTAQVIAMTISSDIEVATRPLIE 62

Query: 220 HIQARGAAAFVPST 261
              A G    +P T
Sbjct: 63  QAWAEGKMVVIPKT 76



 Score = 39.5 bits (88), Expect = 0.080
 Identities = 15/32 (46%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGD-RLGHGGGYYDKFITN 479
           +DLI+ PG+ +SR    R+G GGGYYD+++ +
Sbjct: 114 IDLILVPGLGYSRDRHARIGFGGGYYDRYLAD 145


>UniRef50_A0Z2P3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; marine gamma proteobacterium HTCC2080|Rep:
           5-formyltetrahydrofolate cyclo-ligase - marine gamma
           proteobacterium HTCC2080
          Length = 184

 Score = 39.9 bits (89), Expect = 0.060
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
 Frame = +3

Query: 312 MPKTKHGISQHG--KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           +P+    +  +G  +  A    L+   +DL + P +A  + G RLG+GGGYYD+ +
Sbjct: 88  VPRDTFEVGHYGIAEPPATAKTLDISAIDLFLIPLLACDQYGTRLGYGGGYYDRLL 143


>UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 246

 Score = 39.9 bits (89), Expect = 0.060
 Identities = 21/40 (52%), Positives = 26/40 (65%), Gaps = 5/40 (12%)
 Frame = +3

Query: 381 GGLDLIIAPGVAFS---RSG--DRLGHGGGYYDKFITNLR 485
           GGLD+I+ PGVAF    +S    RLGHG G+YD F+   R
Sbjct: 143 GGLDMILLPGVAFDIDPKSSFIRRLGHGKGFYDYFLHRYR 182


>UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Legionella pneumophila|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 193

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 20/37 (54%), Positives = 22/37 (59%)
 Frame = +3

Query: 369 ALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           AL    LDLII P VAF     RLG G GYYD+ + N
Sbjct: 113 ALPIDELDLIIMPLVAFDAHCTRLGMGSGYYDRTLAN 149



 Score = 33.1 bits (72), Expect = 6.9
 Identities = 19/72 (26%), Positives = 32/72 (44%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K  LRN I    + L+   +   S  +  ++ +   Y+ + RIALY +   E+D   L K
Sbjct: 6   KVALRNTIKQVRSKLSVPYRTASSNQICTRIRSLEQYRQAKRIALYFAVNGEVDLTFLWK 65

Query: 220 HIQARGAAAFVP 255
               +G   + P
Sbjct: 66  SAPLQGKYCYFP 77


>UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1;
           Aquifex aeolicus|Rep: Putative uncharacterized protein -
           Aquifex aeolicus
          Length = 186

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 19/62 (30%), Positives = 34/62 (54%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           K+ LR ++  K   L+ EE++R S+ V   + +   +K S ++ALY   + E+D  PL  
Sbjct: 3   KSELRKKVLHKRINLSEEERRRLSEKVISNLKSLPEFKKSKKVALYCPIKGEVDLTPLFP 62

Query: 220 HI 225
            +
Sbjct: 63  EV 64



 Score = 39.5 bits (88), Expect = 0.080
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +D I  PGVAF   G RLG G GYYD+ +  ++
Sbjct: 112 VDFIAVPGVAFDLEGYRLGFGKGYYDRLLKRVK 144


>UniRef50_A7I2Y8 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=1; Campylobacter hominis ATCC BAA-381|Rep:
           5,10-methenyltetrahydrofolate synthetase - Campylobacter
           hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146
           /CH001A)
          Length = 207

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 16/37 (43%), Positives = 23/37 (62%)
 Frame = +3

Query: 384 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           GLD+ I P +    +  R+GHG GYYD F ++L+  P
Sbjct: 110 GLDMAIIPCIGVDGNFARIGHGKGYYDIFFSHLKTKP 146


>UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Marinomonas|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Marinomonas sp. MWYL1
          Length = 194

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 16/33 (48%), Positives = 21/33 (63%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           LD+++ P V F   G RLG GGG+YD+   N R
Sbjct: 121 LDIVLLPLVGFDSKGGRLGMGGGFYDRTFENKR 153


>UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Parvularcula bermudensis HTCC2503|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Parvularcula
           bermudensis HTCC2503
          Length = 159

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 16/31 (51%), Positives = 22/31 (70%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +I+ P +A    G RLGHGGGYYD+ ++ LR
Sbjct: 82  IIVTPLLAVRPDGARLGHGGGYYDRTLSALR 112



 Score = 34.3 bits (75), Expect = 3.0
 Identities = 16/32 (50%), Positives = 19/32 (59%)
 Frame = +1

Query: 160 SRIALYMSTENEIDTAPLIKHIQARGAAAFVP 255
           S IALY     E+DTAPL K +  RG A  +P
Sbjct: 10  SAIALYAPKGQELDTAPLAKRLSERGHAILLP 41


>UniRef50_A1ZJP2 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=1; Microscilla marina ATCC 23134|Rep:
           5,10-methenyltetrahydrofolate synthetase - Microscilla
           marina ATCC 23134
          Length = 190

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 16/38 (42%), Positives = 26/38 (68%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +D +I P + F + G R+G+GGG+YD+F+   R  P+T
Sbjct: 119 IDWVIVPLLCFDQHGYRVGYGGGFYDRFLA--RCTPKT 154


>UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4;
           Neisseria|Rep: Putative uncharacterized protein -
           Neisseria meningitidis serogroup C / serotype 2a (strain
           ATCC 700532 /FAM18)
          Length = 219

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 1/86 (1%)
 Frame = +3

Query: 231 QRGCGLRAQYAGGRMRMLHLETGDEQTMPKTK-HGISQHGKDQARDDALETGGLDLIIAP 407
           +RG  L   Y   R R +      E  M + +  G ++    Q     +   GL +++ P
Sbjct: 93  KRGAKLYLPYIEPRSRRMWFTPYPESGMERERIRGRARLNVPQFAGRKIRVHGLSVLLVP 152

Query: 408 GVAFSRSGDRLGHGGGYYDKFITNLR 485
            V   R G RLG  GGYYD  +  ++
Sbjct: 153 LVGIDREGYRLGQAGGYYDATLAAMK 178


>UniRef50_Q1JSS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=1; Toxoplasma gondii|Rep:
           5-formyltetrahydrofolate cyclo-ligase, putative -
           Toxoplasma gondii
          Length = 181

 Score = 39.5 bits (88), Expect = 0.080
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITN--LRLNPETAPK*LQWL----LTVKLSTRC 551
           D+++ P + F R G RLG+GGG       +   R +    P+ L W     LTVK S + 
Sbjct: 105 DVVLVPLLGFDRLGRRLGYGGGAQSDHSRSGFSRRSLRDTPQCLSWFVGSRLTVKKSMKF 164

Query: 552 RLTNKTRKWT 581
           R  + T +WT
Sbjct: 165 RRKDSTSRWT 174


>UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1;
           Bifidobacterium longum|Rep: Putative uncharacterized
           protein - Bifidobacterium longum
          Length = 249

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 21/77 (27%), Positives = 39/77 (50%)
 Frame = +1

Query: 40  KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 219
           KA LR+ I ++   +  EE+    +++  +   H   +    +A Y+S  +EI+T PL++
Sbjct: 28  KATLRHHILSRRKRVPAEERGAAGELLVRRFPAHM-IQDGPTVAAYVSMGSEIETRPLLR 86

Query: 220 HIQARGAAAFVPSTPEG 270
            ++A G    VP    G
Sbjct: 87  WLRAHGCHVLVPRLGSG 103



 Score = 37.1 bits (82), Expect = 0.43
 Identities = 17/34 (50%), Positives = 23/34 (67%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           +ALE    DL+IAP +A    G+RLG G G+YD+
Sbjct: 153 EALEKA--DLVIAPALAVDPQGNRLGRGAGWYDR 184


>UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=2; Idiomarina|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Idiomarina loihiensis
          Length = 195

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 19/63 (30%), Positives = 34/63 (53%)
 Frame = +3

Query: 279 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           +L L    +  M   K+GI +   +    + +    + +++ P V F ++G+RLG GGGY
Sbjct: 86  LLFLRYTPDTPMTLNKYGIQE--PELNVQNMVPLSNIQILLMPLVGFDQNGNRLGMGGGY 143

Query: 459 YDK 467
           YD+
Sbjct: 144 YDR 146


>UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=16; Pseudomonadaceae|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 230

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
 Frame = +1

Query: 25  KPNP-AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEID 201
           +P P ++  LR  +     AL+  E+++ +  +Y ++     ++ +  ++LY+ T+ EID
Sbjct: 32  EPAPLSRPQLRRMLRKARRALSPAEQRQAALGLYRQLAQDPVFRRARHLSLYLPTDGEID 91

Query: 202 TAPLIKHIQARGAAAFVP 255
              L++  Q RG A ++P
Sbjct: 92  PRLLLRAAQRRGKATYLP 109



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 16/32 (50%), Positives = 21/32 (65%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LDL++ P V F   G RLG GGG+YD+ +  L
Sbjct: 153 LDLVLLPLVGFDEEGGRLGMGGGFYDRSLAYL 184


>UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp.
           PCC 6803|Rep: Sll1643 protein - Synechocystis sp.
           (strain PCC 6803)
          Length = 188

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 15/31 (48%), Positives = 22/31 (70%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +DL++ P +A  R G RLG+GGGYYD+   +
Sbjct: 113 VDLLLVPCLAGDRQGYRLGYGGGYYDRLFAD 143


>UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=5; canis group|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Ehrlichia chaffeensis str. Sapulpa
          Length = 180

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 16/34 (47%), Positives = 24/34 (70%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           +++I P +AF +  +RLG GGGYYD  I+ L+ N
Sbjct: 109 NILIVPLIAFDKCLNRLGFGGGYYDNTISKLKPN 142


>UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Prosthecochloris aestuarii DSM 271|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
           aestuarii DSM 271
          Length = 197

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 17/32 (53%), Positives = 22/32 (68%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           D+II P VA  RSG R+G+G G YD+F   L+
Sbjct: 123 DVIIVPLVAADRSGTRIGYGAGCYDRFFAALQ 154


>UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Alkalilimnicola
           ehrlichei (strain MLHE-1)
          Length = 209

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 16/26 (61%), Positives = 19/26 (73%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYD 464
           LDL++ P VAF   G RLG GGG+YD
Sbjct: 126 LDLVLTPLVAFDHRGGRLGMGGGFYD 151



 Score = 35.1 bits (77), Expect = 1.7
 Identities = 16/75 (21%), Positives = 38/75 (50%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           +R+ + A+  A     ++  ++ +  +V  H   ++  R+A +M  + E+D  PL++ + 
Sbjct: 15  VRHAMRARRRAQPMAVRRWAARQLARRVARHPLLRNVRRLAAFMPADGEMDPLPLMRRLH 74

Query: 229 ARGAAAFVPSTPEGA 273
            RG   ++P    G+
Sbjct: 75  RRGITLYLPVVRPGS 89


>UniRef50_A6GU56 Cluster: Putative uncharacterized protein; n=1;
           Limnobacter sp. MED105|Rep: Putative uncharacterized
           protein - Limnobacter sp. MED105
          Length = 189

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 15/37 (40%), Positives = 25/37 (67%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           D+++ P +AF R G RLG+G G+YD+ ++ +   P T
Sbjct: 114 DVLLIPCLAFHREGARLGYGAGWYDRTLSQMPEKPVT 150


>UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein
           Rgryl_01000426; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000426 - Rickettsiella
           grylli
          Length = 195

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 17/46 (36%), Positives = 26/46 (56%)
 Frame = +3

Query: 357 ARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           +R   +    +DL+  P + F+  G RLG G G+YDK  + L L+P
Sbjct: 106 SRTTCIAAAAIDLVFVPLLGFTEKGQRLGRGAGFYDKSFSFL-LHP 150


>UniRef50_Q3AZ02 Cluster: Putative uncharacterized protein; n=2;
           Synechococcus|Rep: Putative uncharacterized protein -
           Synechococcus sp. (strain CC9902)
          Length = 203

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           L+   + L++ P +A   SG RLG+GGGYYD+
Sbjct: 119 LQAQEISLLLVPALAVDSSGVRLGYGGGYYDR 150


>UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Hahella chejuensis KCTC 2396|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Hahella
           chejuensis (strain KCTC 2396)
          Length = 190

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 16/34 (47%), Positives = 23/34 (67%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL 488
           L ++  P VAF + G+RLG GGGYYD+   + R+
Sbjct: 109 LHVVCFPLVAFDKQGNRLGMGGGYYDRTFADRRV 142


>UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Alphaproteobacteria|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Magnetospirillum gryphiswaldense
          Length = 200

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 15/31 (48%), Positives = 23/31 (74%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +++ P +AF  +G RLG+GGGYYD+ +  LR
Sbjct: 126 VLLLPLLAFDAAGYRLGYGGGYYDRTLDQLR 156


>UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Nitrococcus mobilis Nb-231|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Nitrococcus
           mobilis Nb-231
          Length = 210

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 17/33 (51%), Positives = 21/33 (63%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           LDL++ P VAF + G RLG G G+YD     LR
Sbjct: 119 LDLVLVPLVAFDQQGHRLGMGAGFYDHTFAFLR 151



 Score = 33.1 bits (72), Expect = 6.9
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
 Frame = +1

Query: 37  AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 216
           +KA LR+ +  +   L   E+ R ++ +   +    WY  S RIA Y + + E+D    +
Sbjct: 3   SKAELRHRMRRQRRQLGLCERTRAARQLTAVLRRSRWYHHSHRIACYWAMDGEMDLGAFL 62

Query: 217 KHIQARGAAAFVP---STPEGA*GCYTWRP 297
           +     G   ++P     P  +   Y +RP
Sbjct: 63  QRAHQDGRVIYLPVLQKKPTKSLRFYQYRP 92


>UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1;
           Actinobacillus pleuropneumoniae L20|Rep: Putative
           uncharacterized protein - Actinobacillus
           pleuropneumoniae serotype 5b (strain L20)
          Length = 191

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +3

Query: 282 LHLETGDEQTMPKT-KHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           L  +  D +T+  T K G+ Q   D  +   L    +++I  P +A  +SG+RLG+GGG+
Sbjct: 90  LFFQQYDAETLFITHKFGMQQPKPDVRKVKPLNE--IEMIFTPLLACDKSGNRLGYGGGF 147

Query: 459 YDKFITNLRLNPE 497
           YD+    L L P+
Sbjct: 148 YDR---TLALTPQ 157


>UniRef50_A3J2X7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=10; Bacteroidetes|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Flavobacteria bacterium BAL38
          Length = 194

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 14/38 (36%), Positives = 27/38 (71%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +D++  P +A+ + G+R+G+G G+YD F++  +  PET
Sbjct: 123 IDVVFVPLLAYDKQGNRVGYGKGFYDNFLS--KCKPET 158


>UniRef50_A1FY99 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=12; Xanthomonadaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Stenotrophomonas maltophilia R551-3
          Length = 197

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 19/54 (35%), Positives = 29/54 (53%)
 Frame = +3

Query: 306 QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           Q +   ++GI +   D   +D LE   + L++ P V F     RLG GGG+YD+
Sbjct: 91  QPLTSNRYGIPE--PDVTVEDTLEPAQMALVVTPLVGFDTQCRRLGMGGGWYDR 142


>UniRef50_A0RNB2 Cluster: 5,10-methenyltetrahydrofolate synthetase;
           n=1; Campylobacter fetus subsp. fetus 82-40|Rep:
           5,10-methenyltetrahydrofolate synthetase - Campylobacter
           fetus subsp. fetus (strain 82-40)
          Length = 209

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 19/56 (33%), Positives = 27/56 (48%)
 Frame = +3

Query: 333 ISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           IS+    +A +       +DL + P V    +  R+GHG GYYD+F   L   P T
Sbjct: 95  ISKFNVKEANNSNAFLKSIDLAVIPVVGVDGNMARIGHGMGYYDRFFAELSYTPIT 150


>UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Methanospirillum hungatei JF-1|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 193

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 14/26 (53%), Positives = 20/26 (76%)
 Frame = +3

Query: 399 IAPGVAFSRSGDRLGHGGGYYDKFIT 476
           I P + F RSG R+G+G GYYD+F++
Sbjct: 120 IIPMLGFDRSGGRIGYGAGYYDRFLS 145


>UniRef50_Q9Z7E3 Cluster: Formyltetrahydrofolate Cycloligase; n=4;
           Chlamydophila|Rep: Formyltetrahydrofolate Cycloligase -
           Chlamydia pneumoniae (Chlamydophila pneumoniae)
          Length = 180

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 15/45 (33%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
 Frame = +3

Query: 342 HGKDQ-ARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           H KD  ++   + +  +  ++ PG+AF + G RLG+G G+YD+++
Sbjct: 98  HPKDPFSKQTPISSDKITHVLVPGLAFDQQGYRLGYGHGFYDRWL 142


>UniRef50_Q6MNQ4 Cluster: InterPro: 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Bdellovibrio bacteriovorus|Rep:
           InterPro: 5-formyltetrahydrofolate cyclo-ligase -
           Bdellovibrio bacteriovorus
          Length = 189

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 22/74 (29%), Positives = 38/74 (51%)
 Frame = +3

Query: 246 LRAQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSR 425
           L  ++A  +MR   LE  + +      +G+ +      +    E  GL   + PG+ F++
Sbjct: 70  LHLKWAFPKMREGLLEFYETRDFDLGPYGVREPKPGSFQRSLAEMSGL---LVPGLVFNK 126

Query: 426 SGDRLGHGGGYYDK 467
           +G+RLG G G+YDK
Sbjct: 127 NGNRLGKGKGFYDK 140


>UniRef50_Q5NR15 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Zymomonas mobilis|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Zymomonas mobilis
          Length = 220

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 16/26 (61%), Positives = 19/26 (73%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDK 467
           D+I+ P V F RS  RLG GGGYYD+
Sbjct: 151 DIILTPLVGFDRSLRRLGRGGGYYDR 176


>UniRef50_Q0F944 Cluster: Putative 5-formyltetrahydrofolate
           cyclo-ligase; n=1; alpha proteobacterium HTCC2255|Rep:
           Putative 5-formyltetrahydrofolate cyclo-ligase - alpha
           proteobacterium HTCC2255
          Length = 188

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 15/26 (57%), Positives = 20/26 (76%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDK 467
           D+II P  AF  +G RLG+GGG+YD+
Sbjct: 116 DIIITPLAAFDMNGYRLGYGGGFYDR 141


>UniRef50_A7BS36 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Beggiatoa sp. PS|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Beggiatoa sp. PS
          Length = 142

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 14/35 (40%), Positives = 23/35 (65%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           +D+I+ P + F   G R+G+G G+YD+F+   R N
Sbjct: 69  IDMILLPLLCFDERGFRVGYGKGFYDRFLVKCRSN 103


>UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Congregibacter litoralis KT71|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Congregibacter litoralis KT71
          Length = 217

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 16/28 (57%), Positives = 20/28 (71%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKF 470
           L L+I P V ++  G RLG GGGYYD+F
Sbjct: 142 LQLVILPTVGWTARGFRLGMGGGYYDRF 169



 Score = 33.5 bits (73), Expect = 5.2
 Identities = 21/96 (21%), Positives = 43/96 (44%)
 Frame = +1

Query: 7   GRMSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMST 186
           G  S   P  ++   R+ +  +  A+     +   + V   + N S++ S+  IALY++ 
Sbjct: 23  GTNSAANPTLSRQACRSHLRQQRRAIAPSYAREAGERVAHYLRNSSFW-SADHIALYLAN 81

Query: 187 ENEIDTAPLIKHIQARGAAAFVPSTPEGA*GCYTWR 294
           + E+D A + +  ++ G   ++P     A     WR
Sbjct: 82  DGELDPAVIARAARSSGKHLYLPVITAEAMAFCEWR 117


>UniRef50_A3YY34 Cluster: Putative uncharacterized protein; n=1;
           Synechococcus sp. WH 5701|Rep: Putative uncharacterized
           protein - Synechococcus sp. WH 5701
          Length = 202

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           L    L L++ P +AF R G RLG+GGG++D+
Sbjct: 116 LPATALGLLLVPALAFDRRGFRLGYGGGWFDR 147


>UniRef50_A1BBF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=4; Rhodobacteraceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Paracoccus denitrificans (strain Pd 1222)
          Length = 239

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 17/37 (45%), Positives = 25/37 (67%)
 Frame = +3

Query: 375 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           ET   D+++AP V +  SG RLG+GGGY+D+ +   R
Sbjct: 163 ETVKPDVVLAPLVGWDGSGYRLGYGGGYFDRTLAARR 199


>UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium diphtheriae|Rep: Putative
           uncharacterized protein - Corynebacterium diphtheriae
          Length = 194

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           +DLII P +  + SG RLG G GYYD+ +  +
Sbjct: 124 VDLIIVPALGITPSGRRLGQGAGYYDRALAGV 155


>UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=3; Geobacter|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Geobacter sp. FRC-32
          Length = 201

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 13/27 (48%), Positives = 21/27 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           +D+ + PGVAF  +G R+G+G G+YD+
Sbjct: 130 IDIFVIPGVAFDINGRRIGYGKGFYDR 156


>UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate
           cyclo-ligase-related protein; n=3; Actinobacteria
           (class)|Rep: 5-formyltetrahydrofolate
           cyclo-ligase-related protein - marine actinobacterium
           PHSC20C1
          Length = 196

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 15/36 (41%), Positives = 23/36 (63%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           +DLII P  +  R+G R+G G GY+DK + ++   P
Sbjct: 121 VDLIIVPAASVDRTGMRMGWGRGYFDKTLGSMETKP 156


>UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Candidatus Desulfococcus oleovorans
           Hxd3|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Candidatus Desulfococcus oleovorans Hxd3
          Length = 195

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 17/44 (38%), Positives = 23/44 (52%)
 Frame = +3

Query: 351 DQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D  R   +    +++ I PG+ F   G R+G G GYYDK I  L
Sbjct: 111 DPNRCRVVPIDSVEIAIIPGLVFDEKGARIGLGTGYYDKLIPKL 154



 Score = 37.1 bits (82), Expect = 0.43
 Identities = 16/65 (24%), Positives = 34/65 (52%)
 Frame = +1

Query: 61  IAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGA 240
           +  KI A T +E  ++S+ +  ++   + +  +  + +Y++   E+DT  +IKH  +   
Sbjct: 15  VVKKIGAFTKDELSQKSRQILTRLFGFANFMEARVVFIYLNKPGEVDTRSIIKHCFSCNK 74

Query: 241 AAFVP 255
            A VP
Sbjct: 75  VAVVP 79


>UniRef50_O26306 Cluster: Conserved protein; n=1;
           Methanothermobacter thermautotrophicus str. Delta H|Rep:
           Conserved protein - Methanobacterium thermoautotrophicum
          Length = 338

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 16/87 (18%)
 Frame = +3

Query: 273 MRMLHLETGDEQTMP--KTKHGISQHGKDQARDDALET-GG-------------LDLIIA 404
           +R L LE G +  MP  K K G    G D    +A  T GG             +DL++ 
Sbjct: 197 VRRLVLEAGKDLIMPTPKIKDGYLLIGGDVPDAEAASTIGGAYMYGSPIREFPQVDLVVE 256

Query: 405 PGVAFSRSGDRLGHGGGYYDKFITNLR 485
             VA    G+RLG GGGY D+ I+ LR
Sbjct: 257 GSVAVDLQGNRLGKGGGYGDREISELR 283


>UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Thiobacillus denitrificans ATCC
           25259|Rep: 5-formyltetrahydrofolate cyclo-ligase family
           protein - Thiobacillus denitrificans (strain ATCC 25259)
          Length = 199

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 16/26 (61%), Positives = 18/26 (69%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYD 464
           LDL++ P V F   G RLG GGGYYD
Sbjct: 115 LDLLLMPLVGFDTDGYRLGMGGGYYD 140


>UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; uncultured bacterium 311|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           uncultured bacterium 311
          Length = 192

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 17/35 (48%), Positives = 21/35 (60%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 491
           LDL++ P VAF   G RLG G GYYD      ++N
Sbjct: 118 LDLVVIPLVAFDNEGFRLGMGKGYYDFTFGTSKIN 152


>UniRef50_Q4E7I6 Cluster: Protein; n=5; Wolbachia|Rep: Protein -
           Wolbachia endosymbiont of Drosophila simulans
          Length = 183

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           D II P +AF    +RLG GGG+YD  I  LR
Sbjct: 101 DTIITPVIAFDDHFNRLGFGGGWYDTMIKKLR 132


>UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Baumannia cicadellinicola str. Hc
           (Homalodisca coagulata)|Rep: 5-formyltetrahydrofolate
           cyclo-ligase family protein - Baumannia cicadellinicola
           subsp. Homalodisca coagulata
          Length = 202

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 15/29 (51%), Positives = 20/29 (68%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI 473
           LD+   P VAF   G+RLG GGG+YD+ +
Sbjct: 122 LDICFIPLVAFDNYGNRLGMGGGFYDRML 150


>UniRef50_Q12FT0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=7; Comamonadaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 212

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           L+  P V +   G RLG+GGG+YD+ +  L+  P T
Sbjct: 142 LLFVPCVGYGPGGYRLGYGGGFYDRTLATLQPRPVT 177


>UniRef50_A2SL05 Cluster: Putative uncharacterized protein; n=1;
           Methylibium petroleiphilum PM1|Rep: Putative
           uncharacterized protein - Methylibium petroleiphilum
           (strain PM1)
          Length = 203

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 16/36 (44%), Positives = 22/36 (61%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           L++ P V F   G RLG+GGG+YD+ +  L   P T
Sbjct: 131 LLLVPCVGFGPKGLRLGYGGGFYDRTLAALEPRPFT 166


>UniRef50_A1G3P7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Salinispora|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Salinispora arenicola CNS205
          Length = 209

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           DL++ P VA  R G RLG GGG YD+ +  +
Sbjct: 132 DLVVLPAVAVDRRGVRLGRGGGSYDRALARV 162


>UniRef50_Q2H2V3 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 249

 Score = 37.5 bits (83), Expect = 0.32
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 5/34 (14%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGD-----RLGHGGGYYDKFI 473
           LDL++ PGVAF    D     RLGHG G+YD F+
Sbjct: 150 LDLVLMPGVAFDTHPDNGAIRRLGHGRGFYDYFL 183


>UniRef50_UPI0000E0F49C Cluster: hypothetical
           5-formyltetrahydrofolatecyclo-ligase-family protein;
           n=1; alpha proteobacterium HTCC2255|Rep: hypothetical
           5-formyltetrahydrofolatecyclo-ligase-family protein -
           alpha proteobacterium HTCC2255
          Length = 211

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 19/63 (30%), Positives = 30/63 (47%)
 Frame = +3

Query: 279 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 458
           +L +    +  M K K GI +        D +    ++ I  P V F   G+R+G GGG+
Sbjct: 90  LLFVRYTSQSNMTKNKFGIPE--PQLTTQDIIPIHTINRIFVPLVGFDDQGNRMGMGGGF 147

Query: 459 YDK 467
           YD+
Sbjct: 148 YDR 150


>UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Anaplasma|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Anaplasma marginale (strain St. Maries)
          Length = 178

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 17/32 (53%), Positives = 21/32 (65%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +++  P VAF RS +RLG GGGYYD  I   R
Sbjct: 100 EVLFVPLVAFDRSLNRLGFGGGYYDYTIAFFR 131


>UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Frankia|Rep: 5-formyltetrahydrofolate cyclo-ligase
           - Frankia sp. (strain CcI3)
          Length = 259

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 14/31 (45%), Positives = 21/31 (67%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           D++I P +A  R+G RLG GGG YD+ +  +
Sbjct: 174 DVVIIPALAVDRTGRRLGRGGGSYDRVLARV 204


>UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate
           cyclo-ligase; n=1; Erythrobacter litoralis HTCC2594|Rep:
           Possible 5-formyltetrahydrofolate cyclo-ligase -
           Erythrobacter litoralis (strain HTCC2594)
          Length = 180

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 12/30 (40%), Positives = 23/30 (76%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           D ++ P + F+ +G+RLG GGG+YD+++ +
Sbjct: 110 DCLLIPLIGFTATGERLGQGGGHYDQWLAD 139


>UniRef50_Q15Q29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Pseudoalteromonas atlantica T6c|Rep:
           5-formyltetrahydrofolate cyclo-ligase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 198

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 16/34 (47%), Positives = 21/34 (61%)
 Frame = +3

Query: 366 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           D +    LD+I  P VAF  +  RLG GGG+YD+
Sbjct: 115 DIVPIAKLDVIFTPLVAFDDTAQRLGMGGGFYDR 148


>UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
           n=1; Orientia tsutsugamushi Boryong|Rep:
           5-Formyltetrahydrofolate cyclo-ligase - Orientia
           tsutsugamushi (strain Boryong) (Rickettsia
           tsutsugamushi)
          Length = 190

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 13/30 (43%), Positives = 22/30 (73%)
 Frame = +3

Query: 396 IIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           ++ PG+ F  +G R+G G GYYD++I+ +R
Sbjct: 119 LLVPGLVFDVAGYRIGFGKGYYDQYISQVR 148


>UniRef50_A2U0W8 Cluster: Putative uncharacterized protein; n=3;
           Flavobacteria|Rep: Putative uncharacterized protein -
           Polaribacter dokdonensis MED152
          Length = 363

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 24/63 (38%), Positives = 31/63 (49%)
 Frame = -2

Query: 709 TAKFTIYFLKIIVQRIVGTPNILWVRFLHVSV*LQYLFSEYNLVHFLVLFVSRHLVDNLT 530
           T  F  YFL I V +I+G   IL +     S+   YLFS   LV  L +FV   L   ++
Sbjct: 107 TGHFNTYFLVIDVLQIIGLSLILIISIYFFSLKKTYLFSAVTLVLALSIFVCEPLYRGIS 166

Query: 529 VKS 521
           V S
Sbjct: 167 VDS 169


>UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Chlorobium phaeobacteroides DSM 266|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Chlorobium
           phaeobacteroides (strain DSM 266)
          Length = 216

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           LD ++ P VA    G RLG+G G+YD+F + L
Sbjct: 138 LDAVLVPVVAADHRGYRLGYGKGFYDRFFSRL 169


>UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Rep:
           ADL385Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 218

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
 Frame = +3

Query: 261 AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETG-----GLDLIIAPGVAF-S 422
           AG  MR  HL     Q+M   +  +   GK   R+   E        +D+++ PG+ F +
Sbjct: 86  AGSHMRR-HLTFYHMQSMAAVR-ALRPQGKYGLREPPAEAPPPALPDVDVVLMPGLGFCA 143

Query: 423 RSGDRLGHGGGYYDKFIT 476
            +G RLG G GYYD +++
Sbjct: 144 DTGARLGRGAGYYDNYVS 161


>UniRef50_Q4JU08 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           uncharacterized protein - Corynebacterium jeikeium
           (strain K411)
          Length = 204

 Score = 36.7 bits (81), Expect = 0.56
 Identities = 13/31 (41%), Positives = 21/31 (67%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 479
           +D+I+ P ++    G RLG GGG+YD+ + N
Sbjct: 132 VDVIVTPALSIDYHGIRLGQGGGFYDRTLAN 162


>UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Thiomicrospira crunogena XCL-2|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Thiomicrospira
           crunogena (strain XCL-2)
          Length = 192

 Score = 36.7 bits (81), Expect = 0.56
 Identities = 19/69 (27%), Positives = 33/69 (47%)
 Frame = +1

Query: 49  LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 228
           LRN    K   L+ E++   ++     ++  +W +   RIA+Y S + E+ T  LI  + 
Sbjct: 3   LRNTCREKRNQLSPEQQFHHAKKASRLLLRSNWLQRPKRIAVYFSQDGELSTESLIDALW 62

Query: 229 ARGAAAFVP 255
            R    F+P
Sbjct: 63  QRNHQVFLP 71



 Score = 33.9 bits (74), Expect = 4.0
 Identities = 13/27 (48%), Positives = 17/27 (62%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           LDL++ P   F   G R G GGG+YD+
Sbjct: 115 LDLVLMPLTCFDLEGHRTGMGGGFYDR 141


>UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Xanthobacter autotrophicus Py2|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Xanthobacter sp.
           (strain Py2)
          Length = 195

 Score = 36.7 bits (81), Expect = 0.56
 Identities = 14/32 (43%), Positives = 22/32 (68%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           +L++ P  AF R G R+G+G G+YD+ +  LR
Sbjct: 119 ELLLVPLAAFDRRGFRIGYGAGFYDRTLALLR 150


>UniRef50_A3U5R6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Croceibacter atlanticus HTCC2559|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Croceibacter
           atlanticus HTCC2559
          Length = 188

 Score = 36.7 bits (81), Expect = 0.56
 Identities = 15/38 (39%), Positives = 25/38 (65%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPET 500
           +D++  P +AF ++G R G+G G+YD F+   +  PET
Sbjct: 116 IDVVFIPLLAFDKTGQRAGYGKGFYDAFLALCK--PET 151


>UniRef50_Q9PLS7 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
           putative; n=4; Chlamydia|Rep: 5-formyltetrahydrofolate
           cyclo-ligase, putative - Chlamydia muridarum
          Length = 178

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 13/25 (52%), Positives = 18/25 (72%)
 Frame = +3

Query: 399 IAPGVAFSRSGDRLGHGGGYYDKFI 473
           + P V F +   RLG+GGGYYD+F+
Sbjct: 118 LVPAVVFDQEQFRLGYGGGYYDRFL 142


>UniRef50_Q477X4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Dechloromonas aromatica RCB|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Dechloromonas
           aromatica (strain RCB)
          Length = 192

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 15/35 (42%), Positives = 22/35 (62%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           D+I+ P   F  +G RLG+GGGY+D+ +  L   P
Sbjct: 120 DMILLPLNGFDAAGYRLGYGGGYFDRTLAALSPRP 154


>UniRef50_Q9F7S8 Cluster: Predicted 5-formyltetrahydrofolate
           cyclo-ligase; n=1; uncultured marine gamma
           proteobacterium EBAC31A08|Rep: Predicted
           5-formyltetrahydrofolate cyclo-ligase -
           Gamma-proteobacterium EBAC31A08
          Length = 191

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 333 ISQHG-KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 482
           I+Q G K+   +D +    +DL+  P      +G RLG+G GY+D+ I ++
Sbjct: 95  INQFGIKEVKSEDYVNINEIDLMFIPMTGVDLNGYRLGYGSGYFDRIIGSI 145


>UniRef50_Q2CK01 Cluster: Putative uncharacterized protein; n=6;
           Alphaproteobacteria|Rep: Putative uncharacterized
           protein - Oceanicola granulosus HTCC2516
          Length = 224

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 17/35 (48%), Positives = 25/35 (71%)
 Frame = +3

Query: 390 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP 494
           +++IAP +    +G RLG+GGGYYD+  T  RL+P
Sbjct: 152 EIVIAPLLGADDAGYRLGNGGGYYDR--TLARLDP 184


>UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=1; Maricaulis maris MCS10|Rep:
           5-formyltetrahydrofolate cyclo-ligase - Maricaulis maris
           (strain MCS10)
          Length = 199

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 16/31 (51%), Positives = 21/31 (67%)
 Frame = +3

Query: 393 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 485
           L++ P +A  RSG+RLG G GYYD  +  LR
Sbjct: 118 LVLVPLLACDRSGNRLGFGKGYYDYTLAALR 148


>UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
           n=2; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
           cyclo-ligase - Mannheimia haemolytica PHL213
          Length = 192

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 14/27 (51%), Positives = 21/27 (77%)
 Frame = +3

Query: 387 LDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           L++I  P VA  ++G+RLG GGG+YD+
Sbjct: 125 LEMIFTPLVACDKAGNRLGMGGGFYDR 151


>UniRef50_A5GRX1 Cluster: 5-formyltetrahydrofolate cyclo-ligase
           family protein; n=1; Synechococcus sp. RCC307|Rep:
           5-formyltetrahydrofolate cyclo-ligase family protein -
           Synechococcus sp. (strain RCC307)
          Length = 183

 Score = 36.3 bits (80), Expect = 0.74
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +3

Query: 372 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 467
           L    + L++ P +A S +G RLG GGG+YD+
Sbjct: 101 LSAEAIGLLLIPALAMSPAGQRLGSGGGWYDR 132


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 772,146,348
Number of Sequences: 1657284
Number of extensions: 16576410
Number of successful extensions: 44786
Number of sequences better than 10.0: 319
Number of HSP's better than 10.0 without gapping: 42275
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44763
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57024798702
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -