BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fbVm0108 (670 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-... 156 5e-37 UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35; Eumetazoa... 133 4e-30 UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol d... 130 4e-29 UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8; Eukaryota|... 128 9e-29 UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD prote... 128 1e-28 UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:... 127 2e-28 UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63... 125 8e-28 UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3; Clostrid... 116 5e-25 UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5; Actino... 116 5e-25 UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx mor... 116 5e-25 UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=... 115 1e-24 UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22; Ascomycota... 111 1e-23 UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 111 2e-23 UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 106 4e-22 UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8; Pezizomycot... 105 1e-21 UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1; S... 105 1e-21 UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|R... 105 1e-21 UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5; Bacillales... 103 3e-21 UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8; Saccharo... 100 4e-20 UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 98 1e-19 UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;... 98 1e-19 UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5; Tric... 98 2e-19 UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6... 95 2e-18 UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 94 2e-18 UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13; Alphap... 93 4e-18 UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain prot... 93 7e-18 UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Re... 93 7e-18 UniRef50_P22144 Cluster: D-xylulose reductase; n=8; Saccharomyce... 93 7e-18 UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain prot... 92 1e-17 UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 92 1e-17 UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1; Bradyrh... 91 2e-17 UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-17 UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-17 UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol dehyd... 90 5e-17 UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus c... 89 9e-17 UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16 UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 86 8e-16 UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15 UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7; Pezizomycot... 85 1e-15 UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) =... 83 4e-15 UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9; cel... 83 4e-15 UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain prot... 83 6e-15 UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1; Carboxydot... 83 8e-15 UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14 UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <... 82 1e-14 UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase s... 81 2e-14 UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain prot... 81 2e-14 UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative; n... 81 2e-14 UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8; Ascomycota... 81 2e-14 UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain prot... 81 3e-14 UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative; n... 80 5e-14 UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2; Saccharomy... 80 5e-14 UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4; Al... 79 7e-14 UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protei... 79 7e-14 UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1; ... 79 7e-14 UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1; ... 79 7e-14 UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein NCU070... 79 1e-13 UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1; F... 78 2e-13 UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Re... 77 3e-13 UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain prot... 75 1e-12 UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 75 1e-12 UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1; F... 75 1e-12 UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding doma... 74 3e-12 UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococc... 74 4e-12 UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7; Firmicut... 73 5e-12 UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein NCU019... 73 5e-12 UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain prot... 73 5e-12 UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related Zn-... 73 6e-12 UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2; Bacte... 73 6e-12 UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 73 8e-12 UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC ... 72 1e-11 UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Re... 72 1e-11 UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol dehydroge... 71 2e-11 UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;... 71 3e-11 UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding dom... 71 3e-11 UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase; ... 71 3e-11 UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain prot... 71 3e-11 UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 70 4e-11 UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2; ... 69 8e-11 UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily, zinc... 69 1e-10 UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA d... 69 1e-10 UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10 UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil... 68 2e-10 UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol dehydr... 68 2e-10 UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenas... 68 2e-10 UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36; ... 68 2e-10 UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7; Clostridiu... 68 2e-10 UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogen... 68 2e-10 UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28; Bacillale... 67 3e-10 UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase s... 67 3e-10 UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep: ... 67 4e-10 UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2; Trichocomac... 67 4e-10 UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 67 4e-10 UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 66 5e-10 UniRef50_Q5K7P7 Cluster: (R,R)-butanediol dehydrogenase, putativ... 66 5e-10 UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n... 66 7e-10 UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;... 66 7e-10 UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protei... 66 7e-10 UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain prot... 66 7e-10 UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 66 1e-09 UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12; Bacteria|... 65 1e-09 UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4; Rhizobiales... 65 2e-09 UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;... 65 2e-09 UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain prot... 65 2e-09 UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase s... 64 2e-09 UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 64 2e-09 UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol dehydroge... 64 2e-09 UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4; Leptos... 64 3e-09 UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 64 3e-09 UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain prot... 64 3e-09 UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain prot... 64 3e-09 UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain prot... 64 4e-09 UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1; Saccha... 64 4e-09 UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative z... 63 5e-09 UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep... 63 5e-09 UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 63 5e-09 UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase, ... 63 5e-09 UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain prot... 63 5e-09 UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellu... 63 5e-09 UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n... 63 5e-09 UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3; Caenorhab... 63 5e-09 UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_030008... 63 7e-09 UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase s... 63 7e-09 UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09 UniRef50_Q11VP8 Cluster: Zinc-type alcohol dehydrogenase; n=2; S... 63 7e-09 UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenas... 62 9e-09 UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:... 62 1e-08 UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain prot... 62 1e-08 UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08 UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41; Bact... 62 1e-08 UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24; Pro... 62 2e-08 UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related Zn-... 62 2e-08 UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain prot... 62 2e-08 UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 62 2e-08 UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella ve... 62 2e-08 UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178; Bac... 62 2e-08 UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8; Bacteria... 61 2e-08 UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase; ... 61 2e-08 UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus amyloliquef... 61 3e-08 UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 61 3e-08 UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protei... 60 4e-08 UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3; Saccharomy... 60 4e-08 UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6; Cyanobacte... 60 5e-08 UniRef50_Q3W6B4 Cluster: Zinc-containing alcohol dehydrogenase s... 60 5e-08 UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 60 5e-08 UniRef50_A7H7S9 Cluster: Alcohol dehydrogenase GroES domain prot... 60 5e-08 UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protei... 60 6e-08 UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase, zinc-binding:Alc... 60 6e-08 UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding dom... 60 6e-08 UniRef50_A1RCH0 Cluster: Putative alcohol dehydrogenase; n=2; Ar... 60 6e-08 UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus... 60 6e-08 UniRef50_Q9HJX2 Cluster: Alcohol dehydrogenase related protein; ... 60 6e-08 UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17; Gammap... 60 6e-08 UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=... 59 8e-08 UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5; P... 59 8e-08 UniRef50_A0QZI7 Cluster: Aryl-alcohol dehydrogenase; n=1; Mycoba... 59 8e-08 UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protei... 59 1e-07 UniRef50_Q0SAT0 Cluster: Zn-containing alcohol dehdyrogenase; n=... 59 1e-07 UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding dom... 59 1e-07 UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol dehydr... 59 1e-07 UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase... 58 1e-07 UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol dehydrog... 58 1e-07 UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol dehyd... 58 1e-07 UniRef50_P14940 Cluster: Alcohol dehydrogenase; n=31; cellular o... 58 1e-07 UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=... 58 2e-07 UniRef50_Q1GKP3 Cluster: Alcohol dehydrogenase GroES-like protei... 58 2e-07 UniRef50_A0NJ16 Cluster: L-iditol 2-dehydrogenase; n=5; Bacteria... 58 2e-07 UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07 UniRef50_A7BDX1 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07 UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain prot... 58 3e-07 UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain prot... 58 3e-07 UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogena... 58 3e-07 UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4; Sulfolobac... 58 3e-07 UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol dehyd... 58 3e-07 UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14; Bacillale... 58 3e-07 UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing;... 57 3e-07 UniRef50_Q5YU97 Cluster: Putative dehydrogenase; n=1; Nocardia f... 57 3e-07 UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protei... 57 3e-07 UniRef50_A6WA66 Cluster: Alcohol dehydrogenase zinc-binding doma... 57 3e-07 UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanic... 57 3e-07 UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like pr... 57 3e-07 UniRef50_P07246 Cluster: Alcohol dehydrogenase III, mitochondria... 57 3e-07 UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyc... 57 4e-07 UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Re... 57 4e-07 UniRef50_Q0SDC0 Cluster: Zn-binding alcohol dehydrogenase; n=1; ... 57 4e-07 UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=... 57 4e-07 UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 57 4e-07 UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 57 4e-07 UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07 UniRef50_A6S0I2 Cluster: Putative uncharacterized protein; n=1; ... 57 4e-07 UniRef50_Q96XE0 Cluster: NAD-dependent alcohol dehydrogenase; n=... 57 4e-07 UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n... 56 6e-07 UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep: ... 56 6e-07 UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3; A... 56 6e-07 UniRef50_Q0S5T4 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 56 6e-07 UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15; Mycob... 56 6e-07 UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 56 6e-07 UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain prot... 56 6e-07 UniRef50_A5VBI0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 56 6e-07 UniRef50_A1SI01 Cluster: Alcohol dehydrogenase GroES domain prot... 56 6e-07 UniRef50_A7R304 Cluster: Chromosome undetermined scaffold_469, w... 56 6e-07 UniRef50_A1D1F8 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 56 6e-07 UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured crenarch... 56 6e-07 UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1; S... 56 8e-07 UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogen... 56 8e-07 UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase s... 56 8e-07 UniRef50_Q1ARB8 Cluster: Alcohol dehydrogenase, zinc-binding pro... 56 8e-07 UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain prot... 56 8e-07 UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding dom... 56 8e-07 UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;... 56 8e-07 UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol dehydrog... 56 1e-06 UniRef50_Q0RIJ3 Cluster: Putative Zn-dependent alcohol dehydroge... 56 1e-06 UniRef50_A7NMA5 Cluster: Alcohol dehydrogenase GroES domain prot... 56 1e-06 UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 56 1e-06 UniRef50_A1SJ83 Cluster: Alcohol dehydrogenase GroES domain prot... 56 1e-06 UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1; Arthr... 56 1e-06 UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06 UniRef50_Q5B536 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06 UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase; ... 55 1e-06 UniRef50_Q0K0E7 Cluster: Zinc-type alcohol dehydrogenase adhd; n... 55 1e-06 UniRef50_A6PRU8 Cluster: Alcohol dehydrogenase GroES domain prot... 55 1e-06 UniRef50_A5V832 Cluster: Alcohol dehydrogenase GroES domain prot... 55 1e-06 UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06 UniRef50_A4RNL2 Cluster: Putative uncharacterized protein; n=3; ... 55 1e-06 UniRef50_A3H5I8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 55 1e-06 UniRef50_P77316 Cluster: Uncharacterized zinc-type alcohol dehyd... 55 1e-06 UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogen... 55 2e-06 UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine dehydr... 55 2e-06 UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain prot... 55 2e-06 UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol dehydroge... 55 2e-06 UniRef50_Q5KJW4 Cluster: Zinc-type alcohol dehydrogenase, putati... 55 2e-06 UniRef50_Q2HBT9 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4; Trichocomac... 55 2e-06 UniRef50_Q9A414 Cluster: Alcohol dehydrogenase class III; n=8; P... 54 2e-06 UniRef50_Q74FN3 Cluster: Alcohol dehydrogenase, zinc-containing;... 54 2e-06 UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;... 54 2e-06 UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;... 54 2e-06 UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase s... 54 2e-06 UniRef50_Q1LNT3 Cluster: Alcohol dehydrogenase GroES-like protei... 54 2e-06 UniRef50_Q1A676 Cluster: Alcohol dehydrogenase; n=4; Bacteria|Re... 54 2e-06 UniRef50_Q0S7E4 Cluster: Possible alcohol dehydrogenase; n=2; No... 54 2e-06 UniRef50_A5V7S4 Cluster: Alcohol dehydrogenase, zinc-binding dom... 54 2e-06 UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase; ... 54 2e-06 UniRef50_Q9WYP3 Cluster: Alcohol dehydrogenase, zinc-containing;... 54 3e-06 UniRef50_Q6NC01 Cluster: Possible alcohol dehydrogenase class II... 54 3e-06 UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase s... 54 3e-06 UniRef50_A7B0E7 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06 UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain prot... 54 3e-06 UniRef50_A2R610 Cluster: Catalytic activity:; n=5; Trichocomacea... 54 3e-06 UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain prot... 54 3e-06 UniRef50_O67374 Cluster: Alcohol dehydrogenase; n=1; Aquifex aeo... 54 4e-06 UniRef50_A5IYL7 Cluster: Alcohol dehydrogenase; n=2; Mycoplasma ... 54 4e-06 UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain prot... 54 4e-06 UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 54 4e-06 UniRef50_Q5K773 Cluster: Alcohol dehydrogenase, putative; n=1; F... 54 4e-06 UniRef50_A3MVR8 Cluster: Alcohol dehydrogenase GroES domain prot... 54 4e-06 UniRef50_P07327 Cluster: Alcohol dehydrogenase 1A; n=1281; cellu... 54 4e-06 UniRef50_Q0RGJ0 Cluster: Aryl-alcohol dehydrogenase; n=1; Franki... 53 5e-06 UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 53 5e-06 UniRef50_Q9P6I8 Cluster: Glutathione-dependent formaldehyde dehy... 53 5e-06 UniRef50_Q4P3P9 Cluster: Putative uncharacterized protein; n=1; ... 53 5e-06 UniRef50_A1DJP7 Cluster: Alcohol dehydrogenase, putative; n=5; T... 53 5e-06 UniRef50_Q8PYV2 Cluster: Glutathione-independent formaldehyde de... 53 5e-06 UniRef50_Q5V676 Cluster: Alcohol dehydrogenase; n=7; cellular or... 53 5e-06 UniRef50_A7D2S0 Cluster: Alcohol dehydrogenase GroES domain prot... 53 5e-06 UniRef50_P39849 Cluster: Aryl-alcohol dehydrogenase; n=33; Bacte... 53 5e-06 UniRef50_Q9ZEX7 Cluster: Dehydrogenase; n=1; Thiobacillus sp.|Re... 53 7e-06 UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain prot... 53 7e-06 UniRef50_A7R300 Cluster: Chromosome undetermined scaffold_469, w... 53 7e-06 UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10; Bact... 53 7e-06 UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 52 1e-05 UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;... 52 1e-05 UniRef50_Q7D3N5 Cluster: AGR_pAT_280p; n=3; Alphaproteobacteria|... 52 1e-05 UniRef50_Q7BKE4 Cluster: Predicted Zn-dependent alcohol dehydrog... 52 1e-05 UniRef50_A0JVZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 52 1e-05 UniRef50_Q8J0P3 Cluster: Alcohol dehydrogenase; n=2; Pezizomycot... 52 1e-05 UniRef50_Q6BTK7 Cluster: Similar to sp|Q04894 Saccharomyces cere... 52 1e-05 UniRef50_Q2UHG1 Cluster: Alcohol dehydrogenase; n=8; Dikarya|Rep... 52 1e-05 UniRef50_Q5V607 Cluster: Zinc-binding dehydrogenase; n=5; Haloba... 52 1e-05 UniRef50_Q5V2C1 Cluster: Alcohol dehydrogenase; n=3; Halobacteri... 52 1e-05 UniRef50_O31186 Cluster: Alcohol dehydrogenase; n=105; cellular ... 52 1e-05 UniRef50_UPI000045C1D4 Cluster: COG1063: Threonine dehydrogenase... 52 1e-05 UniRef50_Q88TC0 Cluster: Aryl-alcohol dehydrogenase; n=6; Lactob... 52 1e-05 UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2; Bacter... 52 1e-05 UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain prot... 52 1e-05 UniRef50_A0H1E5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 52 1e-05 UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase; ... 52 1e-05 UniRef50_Q0CK29 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05 UniRef50_Q97ZV3 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 52 1e-05 UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 52 2e-05 UniRef50_Q5YR32 Cluster: Putative dehydrogenase; n=1; Nocardia f... 52 2e-05 UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;... 52 2e-05 UniRef50_Q2G9N3 Cluster: Alcohol dehydrogenase, zinc-containing;... 52 2e-05 UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium aro... 52 2e-05 UniRef50_Q0RVY2 Cluster: Dehydrogenase; n=1; Rhodococcus sp. RHA... 52 2e-05 UniRef50_A2VN88 Cluster: Zinc-type alcohol dehydrogenase (E subu... 52 2e-05 UniRef50_A0QZV9 Cluster: Alcohol dehydrogenase B; n=1; Mycobacte... 52 2e-05 UniRef50_A4VDT7 Cluster: Alcohol dehydrogenase; n=5; Tetrahymena... 52 2e-05 UniRef50_Q6BV88 Cluster: Debaryomyces hansenii chromosome C of s... 52 2e-05 UniRef50_A7EEB7 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_A2QFZ8 Cluster: Catalytic activity: alcohol dehydrogena... 52 2e-05 UniRef50_A1CC26 Cluster: Alcohol dehydrogenase; n=4; cellular or... 52 2e-05 UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 52 2e-05 UniRef50_P20368 Cluster: Alcohol dehydrogenase 1; n=9; Bacteria|... 52 2e-05 UniRef50_UPI00005F10EF Cluster: COG1063: Threonine dehydrogenase... 51 2e-05 UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus ihey... 51 2e-05 UniRef50_Q81RD6 Cluster: Quinone oxidoreductase; n=14; Bacillus|... 51 2e-05 UniRef50_Q04H68 Cluster: Threonine dehydrogenase or related Zn-d... 51 2e-05 UniRef50_A5ZSK2 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05 UniRef50_A4FB48 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05 UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain prot... 51 2e-05 UniRef50_A0V2V8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 51 2e-05 UniRef50_Q4P2L9 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05 UniRef50_Q2TWC7 Cluster: Zn-dependent alcohol dehydrogenases; n=... 51 2e-05 UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 51 2e-05 UniRef50_UPI0000498928 Cluster: zinc-containing alcohol dehydrog... 51 3e-05 UniRef50_Q9A212 Cluster: Quinone oxidoreductase; n=2; Bacteria|R... 51 3e-05 UniRef50_Q8NTH6 Cluster: Zn-dependent alcohol dehydrogenases; n=... 51 3e-05 UniRef50_Q60AS0 Cluster: Alcohol dehydrogenase, zinc-containing;... 51 3e-05 UniRef50_Q0RJI1 Cluster: Putative zinc-binding dehydrogenase; n=... 51 3e-05 UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05 UniRef50_A6M049 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05 UniRef50_A5FWT0 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05 UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_A7SKJ4 Cluster: Predicted protein; n=1; Nematostella ve... 51 3e-05 UniRef50_A4QUV6 Cluster: Putative uncharacterized protein; n=2; ... 51 3e-05 UniRef50_A0RXG2 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 51 3e-05 UniRef50_P77360 Cluster: Uncharacterized zinc-type alcohol dehyd... 51 3e-05 UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3; Rhizob... 50 4e-05 UniRef50_Q81YJ9 Cluster: Quinone oxidoreductase; n=12; Bacteria|... 50 4e-05 UniRef50_Q7NR39 Cluster: Probable glutathione-dependent aldehyde... 50 4e-05 UniRef50_Q84H90 Cluster: 6-hydroxyhexanoate dehydrogenase; n=3; ... 50 4e-05 UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 50 4e-05 UniRef50_A1GB76 Cluster: Alcohol dehydrogenase GroES-like; n=3; ... 50 4e-05 UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogen... 50 4e-05 UniRef50_A0IUR9 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 50 4e-05 UniRef50_A0FSG8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 50 4e-05 UniRef50_Q7PU31 Cluster: ENSANGP00000000280; n=3; cellular organ... 50 4e-05 UniRef50_A6SRD0 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05 UniRef50_A2QWS3 Cluster: Remark: Patentmatch against protein AC ... 50 4e-05 UniRef50_A2QUV3 Cluster: Contig An10c0010, complete genome; n=6;... 50 4e-05 UniRef50_Q8A1P2 Cluster: Sorbitol dehydrogenase; n=4; Bacteroide... 50 5e-05 UniRef50_Q5KW77 Cluster: Alcohol dehydrogenase; n=2; Geobacillus... 50 5e-05 UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;... 50 5e-05 UniRef50_Q47QG1 Cluster: Alcohol dehydrogenase class III; n=1; T... 50 5e-05 UniRef50_Q2AC15 Cluster: Aromatic alcohol dehydrogenase; n=4; Ba... 50 5e-05 UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 50 5e-05 UniRef50_Q0S5L3 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 50 5e-05 UniRef50_A5V690 Cluster: Alcohol dehydrogenase GroES domain prot... 50 5e-05 UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 50 5e-05 UniRef50_Q2GU61 Cluster: Putative uncharacterized protein; n=2; ... 50 5e-05 UniRef50_P47734 Cluster: S-(hydroxymethyl)glutathione dehydrogen... 50 5e-05 UniRef50_P48523 Cluster: Cinnamyl-alcohol dehydrogenase; n=110; ... 50 5e-05 UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenas... 50 7e-05 UniRef50_Q2JCS2 Cluster: Alcohol dehydrogenase GroES-like; n=5; ... 50 7e-05 UniRef50_Q11C06 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 50 7e-05 UniRef50_Q0LFU6 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 50 7e-05 UniRef50_A7HFA6 Cluster: Alcohol dehydrogenase GroES domain prot... 50 7e-05 UniRef50_A6LR91 Cluster: Alcohol dehydrogenase GroES domain prot... 50 7e-05 UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2; ... 50 7e-05 UniRef50_A5N5N6 Cluster: Zn-dependent dehydrogenase; n=1; Clostr... 50 7e-05 UniRef50_A4M1E8 Cluster: Alcohol dehydrogenase GroES domain prot... 50 7e-05 UniRef50_A4FFG8 Cluster: Probable alcohol dehydrogenase; n=1; Sa... 50 7e-05 UniRef50_A3PJU5 Cluster: Alcohol dehydrogenase GroES domain prot... 50 7e-05 UniRef50_Q0IRJ9 Cluster: Os11g0622800 protein; n=4; Oryza sativa... 50 7e-05 UniRef50_A3DNG0 Cluster: Alcohol dehydrogenase GroES domain prot... 50 7e-05 UniRef50_P38230 Cluster: Probable quinone oxidoreductase; n=9; S... 50 7e-05 UniRef50_P00331 Cluster: Alcohol dehydrogenase 2; n=22; Ascomyco... 50 7e-05 UniRef50_Q8EVN7 Cluster: NADP-dependent alcohol dehydrogenase; n... 49 9e-05 UniRef50_Q8ES57 Cluster: NADP-dependent alcohol dehydrogenase; n... 49 9e-05 UniRef50_Q6AA39 Cluster: Zinc-binding dehydrogenase; n=1; Propio... 49 9e-05 UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily, zinc... 49 9e-05 UniRef50_Q392P0 Cluster: Zinc-containing alcohol dehydrogenase s... 49 9e-05 UniRef50_Q0S6W9 Cluster: Zn-binding dehydrogenase; n=4; Actinomy... 49 9e-05 UniRef50_Q0FV22 Cluster: Sorbitol dehydrogenase; n=1; Roseovariu... 49 9e-05 UniRef50_A6AJT3 Cluster: Alcohol dehydrogenase, zinc-containing;... 49 9e-05 UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 49 9e-05 UniRef50_Q0CT00 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05 UniRef50_A1D8I3 Cluster: Alcohol dehydrogenase; n=1; Neosartorya... 49 9e-05 UniRef50_Q97YM2 Cluster: Alcohol dehydrogenase; n=2; Sulfolobus ... 49 9e-05 UniRef50_Q976Y8 Cluster: 344aa long hypothetical alcohol dehydro... 49 9e-05 UniRef50_Q8TTM5 Cluster: Zinc-binding alcohol dehydrogenase; n=3... 49 9e-05 UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 49 9e-05 UniRef50_Q0S728 Cluster: Alcohol dehydrogenase; n=3; Actinomycet... 49 1e-04 UniRef50_Q08XA0 Cluster: Alcohol dehydrogenase; n=2; Cystobacter... 49 1e-04 UniRef50_A6EYW6 Cluster: Zinc-containing alcohol dehydrogenase s... 49 1e-04 UniRef50_A4SZ26 Cluster: Alcohol dehydrogenase, zinc-binding dom... 49 1e-04 UniRef50_A0YEK7 Cluster: Quinone oxidoreductase; n=2; unclassifi... 49 1e-04 UniRef50_A3ASS3 Cluster: Putative uncharacterized protein; n=2; ... 49 1e-04 UniRef50_Q207V9 Cluster: Mannitol dehydrogenase-like; n=3; Physa... 49 1e-04 UniRef50_Q2H9V9 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04 UniRef50_Q8ZU64 Cluster: Alcohol dehydrogenase; n=5; Thermoprote... 49 1e-04 UniRef50_Q9A4J4 Cluster: Alcohol dehydrogenase, zinc-containing;... 48 2e-04 UniRef50_Q89P08 Cluster: Blr3675 protein; n=19; Bacteria|Rep: Bl... 48 2e-04 UniRef50_Q0RV69 Cluster: Alcohol dehydrogenase; n=21; Actinomyce... 48 2e-04 UniRef50_Q0LPP6 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 48 2e-04 UniRef50_A0JVV9 Cluster: Alcohol dehydrogenase GroES domain prot... 48 2e-04 UniRef50_Q66UT6 Cluster: NAD-and Zn-dependent alcohol dehydrogen... 48 2e-04 UniRef50_Q59VG4 Cluster: Potential butanediol dehydrogenase; n=7... 48 2e-04 UniRef50_A6RNK3 Cluster: NADP-dependent alcohol dehydrogenase; n... 48 2e-04 UniRef50_Q97YT7 Cluster: Alcohol dehydrogenase; n=2; Thermoprote... 48 2e-04 UniRef50_P77539 Cluster: Uncharacterized zinc-type alcohol dehyd... 48 2e-04 UniRef50_Q38707 Cluster: Mannitol dehydrogenase; n=41; cellular ... 48 2e-04 UniRef50_P25984 Cluster: NADP-dependent alcohol dehydrogenase; n... 48 2e-04 UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5; Alphapro... 48 2e-04 UniRef50_Q89ZF3 Cluster: Sorbitol dehydrogenase; n=1; Bacteroide... 48 2e-04 UniRef50_Q62CY1 Cluster: Alcohol dehydrogenase, zinc-containing;... 48 2e-04 UniRef50_Q5LS79 Cluster: Alcohol dehydrogenase, zinc-containing;... 48 2e-04 UniRef50_O06012 Cluster: NAD alcohol dehydrogenase; n=31; Bacter... 48 2e-04 UniRef50_A4FD89 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 48 2e-04 UniRef50_A1W2W1 Cluster: Alcohol dehydrogenase GroES domain prot... 48 2e-04 UniRef50_A1R1P7 Cluster: Alcohol dehydrogenase; n=1; Arthrobacte... 48 2e-04 UniRef50_A0KRX9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 48 2e-04 UniRef50_A0IU88 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 48 2e-04 UniRef50_Q0CMV8 Cluster: Alcohol dehydrogenase I; n=2; Aspergill... 48 2e-04 UniRef50_A6RPM4 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A4RI44 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A2QBG7 Cluster: Contig An01c0490, complete genome; n=2;... 48 2e-04 UniRef50_Q97VB8 Cluster: Alcohol dehydrogenase; n=1; Sulfolobus ... 48 2e-04 UniRef50_Q9HTE3 Cluster: Glutathione-independent formaldehyde de... 48 2e-04 UniRef50_Q7UU62 Cluster: Sorbitol dehydrogenase; n=1; Pirellula ... 48 3e-04 UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1; P... 48 3e-04 UniRef50_Q3M191 Cluster: Threonine dehydrogenase and related Zn-... 48 3e-04 UniRef50_Q0SJX5 Cluster: Alcohol dehydrogenase; n=11; Corynebact... 48 3e-04 UniRef50_Q28K81 Cluster: Alcohol dehydrogenase zinc-binding; n=3... 48 3e-04 UniRef50_Q0SJ82 Cluster: Possible alcohol dehydrogenase; n=13; c... 48 3e-04 UniRef50_A6WBA5 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04 UniRef50_A1SLY9 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04 UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04 UniRef50_A0LF03 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04 UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04 UniRef50_Q8J2R1 Cluster: Zbd1p; n=2; Gibberella|Rep: Zbd1p - Gib... 48 3e-04 UniRef50_Q5AY22 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04 UniRef50_A5DYS7 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04 UniRef50_A3HAS3 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 48 3e-04 UniRef50_Q9FH04 Cluster: Alcohol dehydrogenase-like 7; n=11; Mag... 48 3e-04 UniRef50_UPI000023E4F0 Cluster: hypothetical protein FG07506.1; ... 47 4e-04 UniRef50_UPI000023DF5F Cluster: hypothetical protein FG11316.1; ... 47 4e-04 UniRef50_Q9CBQ3 Cluster: Alcohol dehydrogenase; n=4; Actinomycet... 47 4e-04 UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;... 47 4e-04 UniRef50_Q47PU4 Cluster: Oxidoreductase; n=1; Thermobifida fusca... 47 4e-04 UniRef50_Q2SGI4 Cluster: NADPH:quinone reductase and related Zn-... 47 4e-04 UniRef50_Q53929 Cluster: ORF4 protein; n=2; Streptomyces coelico... 47 4e-04 UniRef50_Q0SJ18 Cluster: Probable NADPH:quinone reductase; n=1; ... 47 4e-04 UniRef50_Q0SBJ8 Cluster: Aryl-alcohol dehydrogenase; n=2; Bacter... 47 4e-04 UniRef50_A5ZML1 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04 UniRef50_A5V2Z1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 47 4e-04 UniRef50_A5FC99 Cluster: Alcohol dehydrogenase GroES domain prot... 47 4e-04 UniRef50_A4X844 Cluster: Alcohol dehydrogenase GroES domain prot... 47 4e-04 UniRef50_A1W5R7 Cluster: Alcohol dehydrogenase GroES domain prot... 47 4e-04 UniRef50_A0QRJ4 Cluster: Alcohol dehydrogenase 1; n=2; Corynebac... 47 4e-04 UniRef50_Q0UDN4 Cluster: Putative uncharacterized protein; n=2; ... 47 4e-04 UniRef50_Q0U4V7 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04 UniRef50_A1CIX6 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 47 4e-04 UniRef50_Q820H0 Cluster: Putative dehydrogenase; n=4; Actinomyce... 47 5e-04 UniRef50_Q48FD6 Cluster: Oxidoreductase, zinc-binding; n=2; Pseu... 47 5e-04 UniRef50_Q9F8C7 Cluster: Alcohol dehydrogenase; n=6; Streptococc... 47 5e-04 UniRef50_Q1INA4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 47 5e-04 UniRef50_A7FVI5 Cluster: Oxidoreductase, zinc-binding dehydrogen... 47 5e-04 UniRef50_A5G4J1 Cluster: Alcohol dehydrogenase GroES domain prot... 47 5e-04 UniRef50_A5CZI6 Cluster: Threonine dehydrogenase and related Zn-... 47 5e-04 UniRef50_A4G6Q5 Cluster: Glutathione-independent formaldehyde de... 47 5e-04 UniRef50_A1SIJ4 Cluster: Alcohol dehydrogenase, zinc-binding dom... 47 5e-04 UniRef50_A0HHZ1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 47 5e-04 UniRef50_Q5ANC5 Cluster: Potential zinc-binding dehydrogenase; n... 47 5e-04 UniRef50_A7F361 Cluster: Putative uncharacterized protein; n=1; ... 47 5e-04 UniRef50_A6RJU6 Cluster: Putative uncharacterized protein; n=2; ... 47 5e-04 UniRef50_A4YDW3 Cluster: Alcohol dehydrogenase GroES domain prot... 47 5e-04 UniRef50_UPI0000384B5E Cluster: COG1063: Threonine dehydrogenase... 46 6e-04 UniRef50_Q9PCQ1 Cluster: NADP-alcohol dehydrogenase; n=1; Xylell... 46 6e-04 UniRef50_Q7N973 Cluster: Similarities with different types of de... 46 6e-04 UniRef50_Q49WS6 Cluster: Putative alcohol dehydrogenase; n=1; St... 46 6e-04 UniRef50_Q2JAT4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 46 6e-04 UniRef50_Q13BQ1 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 46 6e-04 UniRef50_A7HAS7 Cluster: Alcohol dehydrogenase GroES domain prot... 46 6e-04 UniRef50_A6WBJ8 Cluster: Alcohol dehydrogenase GroES domain prot... 46 6e-04 UniRef50_A4XIU4 Cluster: Alcohol dehydrogenase GroES domain prot... 46 6e-04 UniRef50_A0M2P9 Cluster: Zinc-type alcohol dehydrogenase; n=3; B... 46 6e-04 UniRef50_Q0UBV8 Cluster: Putative uncharacterized protein; n=2; ... 46 6e-04 UniRef50_P42754 Cluster: Mannitol dehydrogenase; n=40; Spermatop... 46 6e-04 UniRef50_Q89RJ2 Cluster: Blr2780 protein; n=10; Proteobacteria|R... 46 8e-04 UniRef50_Q2SYD8 Cluster: Quinone oxidoreductase; n=1; Burkholder... 46 8e-04 UniRef50_Q0REK8 Cluster: Putative alcohol dehydrogenase class II... 46 8e-04 UniRef50_A6UC14 Cluster: Alcohol dehydrogenase zinc-binding doma... 46 8e-04 UniRef50_A6NT70 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04 UniRef50_A3K4A3 Cluster: Benzyl-alcohol dehydrogenase; n=1; Sagi... 46 8e-04 UniRef50_A1BBK6 Cluster: Alcohol dehydrogenase GroES domain prot... 46 8e-04 UniRef50_O45496 Cluster: Putative uncharacterized protein; n=2; ... 46 8e-04 UniRef50_A0CJM4 Cluster: Chromosome undetermined scaffold_2, who... 46 8e-04 UniRef50_Q55IH4 Cluster: Putative uncharacterized protein; n=2; ... 46 8e-04 UniRef50_Q2U7I8 Cluster: NADPH:quinone reductase and related Zn-... 46 8e-04 UniRef50_Q0UZS7 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04 UniRef50_A3GG69 Cluster: Alcohol dehydrogenase, class III, bacte... 46 8e-04 UniRef50_Q8ZVD9 Cluster: Alcohol dehydrogenase; n=3; Pyrobaculum... 46 8e-04 UniRef50_Q9WYD4 Cluster: Alcohol dehydrogenase, zinc-containing;... 46 0.001 UniRef50_Q9RZE4 Cluster: Alcohol dehydrogenase, zinc-containing;... 46 0.001 UniRef50_Q89IR8 Cluster: Bll5566 protein; n=2; Rhizobiales|Rep: ... 46 0.001 UniRef50_Q3WAW5 Cluster: Zinc-containing alcohol dehydrogenase s... 46 0.001 >UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-PA - Drosophila melanogaster (Fruit fly) Length = 360 Score = 156 bits (378), Expect = 5e-37 Identities = 65/87 (74%), Positives = 73/87 (83%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C+ CK G+Y+LCP M+FCATPP GNL RYYKHAADFCFKLPDHVTMEEGALLE Sbjct: 93 GVPCRKCDHCKQGKYNLCPGMVFCATPPYDGNLTRYYKHAADFCFKLPDHVTMEEGALLE 152 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VG+HACKR V+ G VL+LG P Sbjct: 153 PLSVGVHACKRAEVTLGSKVLILGAGP 179 Score = 121 bits (292), Expect = 1e-26 Identities = 59/90 (65%), Positives = 70/90 (77%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L+ D+RL Q PIPEI++DEVLL MD VGICGSDVHY G+ G FVL +PMI+GHE Sbjct: 8 AVLHGIEDMRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHE 67 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 ++GVVAK+G KV L VGDRVAIEP CR Sbjct: 68 SAGVVAKLGKKVTTLKVGDRVAIEPGVPCR 97 Score = 46.4 bits (105), Expect = 6e-04 Identities = 21/41 (51%), Positives = 29/41 (70%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAE 663 A+A GA ++LI D++Q RLD AK LGA +TLL+ +D E Sbjct: 188 AQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEE 228 >UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35; Eumetazoa|Rep: Sorbitol dehydrogenase - Homo sapiens (Human) Length = 357 Score = 133 bits (321), Expect = 4e-30 Identities = 58/87 (66%), Positives = 67/87 (77%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G P EFCK GRY+L P + FCATPP GNL R+YKH A FC+KLPD+VT EEGAL+E Sbjct: 97 GAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE 156 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VGIHAC+RGGV+ GH VLV G P Sbjct: 157 PLSVGIHACRRGGVTLGHKVLVCGAGP 183 Score = 119 bits (286), Expect = 7e-26 Identities = 52/84 (61%), Positives = 67/84 (79%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ P DLRL PIPE +EVLLRM VGICGSDVHYW+ G+ G+F++++PM++GHEA Sbjct: 13 VVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEA 72 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SG V K+GS VK+L GDRVAIEP Sbjct: 73 SGTVEKVGSSVKHLKPGDRVAIEP 96 Score = 37.9 bits (84), Expect = 0.22 Identities = 18/37 (48%), Positives = 25/37 (67%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDS 651 AKA GA +V++ D+ +RL AK +GAD L I K+S Sbjct: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 228 >UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase); n=1; Homo sapiens|Rep: PREDICTED: similar to Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) - Homo sapiens Length = 323 Score = 130 bits (313), Expect = 4e-29 Identities = 56/91 (61%), Positives = 70/91 (76%) Frame = +2 Query: 254 AGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 +G P EFCK GRY+L P + FCATPP GNL ++YKH A FC+KLPD+VT EEGAL+ Sbjct: 80 SGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCQFYKHNAAFCYKLPDNVTFEEGALI 139 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDPSAS 526 +PL+VGIHAC+RGGV+ GH VLV G +A+ Sbjct: 140 DPLSVGIHACRRGGVTLGHKVLVCGAGSAAT 170 >UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8; Eukaryota|Rep: Sorbitol dehydrogenase - Bos taurus (Bovine) Length = 356 Score = 128 bits (310), Expect = 9e-29 Identities = 56/87 (64%), Positives = 67/87 (77%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G P EFCK GRY+L P + FCATPP GNL R+YKH A+FC+KLPD+VT EEGAL+E Sbjct: 96 GAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIE 155 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VGIHAC+R GV+ G+ VLV G P Sbjct: 156 PLSVGIHACRRAGVTLGNKVLVCGAGP 182 Score = 117 bits (282), Expect = 2e-25 Identities = 52/84 (61%), Positives = 66/84 (78%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ P DLRL PIPE +EVLL+M VGICGSDVHYWQ G+ G FV+++PM++GHEA Sbjct: 12 VVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEA 71 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SG V K+GS V++L GDRVAIEP Sbjct: 72 SGTVVKVGSLVRHLQPGDRVAIEP 95 Score = 37.9 bits (84), Expect = 0.22 Identities = 18/37 (48%), Positives = 25/37 (67%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDS 651 AKA GA +V++ D+ SRL AK +GAD+ L I +S Sbjct: 191 AKAMGAAQVVVTDLSASRLSKAKEVGADFILQISNES 227 >UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD protein; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SORD protein - Strongylocentrotus purpuratus Length = 292 Score = 128 bits (309), Expect = 1e-28 Identities = 54/86 (62%), Positives = 65/86 (75%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C C+ G+Y+LC D+ FCATPPV GNL +YY HAADFCFKLP +V+ EEGAL+E Sbjct: 95 GVPCRMCSLCRVGKYNLCRDVQFCATPPVDGNLSQYYLHAADFCFKLPSNVSYEEGALVE 154 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRD 514 PLAV ++ C R VS G VL+ G D Sbjct: 155 PLAVALYTCSRAEVSLGSKVLICGSD 180 Score = 97.1 bits (231), Expect = 3e-19 Identities = 47/91 (51%), Positives = 60/91 (65%), Gaps = 2/91 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L D+++ Q + +EVLL + VGICGSD+ YW G CG F L PM++GHE Sbjct: 10 AVLCGIKDIKMEQRSVTAPGPNEVLLAVHSVGICGSDLKYWSHGYCGRFKLTAPMVIGHE 69 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CRV 269 ASG VA +G VK+L VGDRVAIEP CR+ Sbjct: 70 ASGTVAALGPGVKHLEVGDRVAIEPGVPCRM 100 >UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep: ENSANGP00000011378 - Anopheles gambiae str. PEST Length = 362 Score = 127 bits (307), Expect = 2e-28 Identities = 55/86 (63%), Positives = 63/86 (73%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + CR C CK GRY++CP ++C T HGNL YY HAAD CFKLP +VTMEEGALLEP Sbjct: 97 IGCRTCRHCKAGRYNICPQGVYCVTTG-HGNLCNYYTHAADCCFKLPANVTMEEGALLEP 155 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 LAVG+H C+RGGV G VLVLG P Sbjct: 156 LAVGVHCCRRGGVGIGSTVLVLGAGP 181 Score = 101 bits (241), Expect = 2e-20 Identities = 47/83 (56%), Positives = 60/83 (72%), Gaps = 2/83 (2%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 D R+ + P+P + EVLL MDCVGICGSDVHY G G + L++ M++GHE+SGVV Sbjct: 18 DFRVEEIPMPRPRDHEVLLEMDCVGICGSDVHYVSHGGFGDYKLKDKMVLGHESSGVVVA 77 Query: 204 IGSKVKNLTVGDRVAIEPA--CR 266 +G+ V +L VGDRVAIEPA CR Sbjct: 78 VGADVTSLQVGDRVAIEPAIGCR 100 Score = 44.8 bits (101), Expect = 0.002 Identities = 20/43 (46%), Positives = 30/43 (69%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AKA GA KV +ID+++ +L+ AK+LGAD TL + + E+V Sbjct: 190 AKAMGAAKVCVIDLVERKLELAKTLGADATLAVSGHDTQDEIV 232 >UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63674 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 594 Score = 125 bits (302), Expect = 8e-28 Identities = 55/87 (63%), Positives = 65/87 (74%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVP EF K+G Y+L P + FCATPP GNL RYYKH+A FC+KLPD+VT EEGAL+E Sbjct: 93 GVPREVDEFVKSGHYNLSPSIFFCATPPDDGNLCRYYKHSASFCYKLPDNVTYEEGALIE 152 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VGIHAC+R GV+ G V V G P Sbjct: 153 PLSVGIHACRRAGVTLGSSVFVCGAGP 179 Score = 115 bits (277), Expect = 9e-25 Identities = 52/84 (61%), Positives = 65/84 (77%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ DLRL Q PIPE ++VLL+M VGICGSDVHYWQ G+ G FV+++PMI+GHEA Sbjct: 9 VLHAKGDLRLEQRPIPEPGPNDVLLQMHSVGICGSDVHYWQNGRIGDFVVKQPMILGHEA 68 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SG V K+GS V +L GDRVA+EP Sbjct: 69 SGRVVKVGSAVTHLKPGDRVAVEP 92 >UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3; Clostridiaceae|Rep: L-iditol 2-dehydrogenase - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 348 Score = 116 bits (279), Expect = 5e-25 Identities = 50/84 (59%), Positives = 60/84 (71%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G C +CEFCKTGRY+LCPD+IF ATPPV G Y H AD CFKLP++V+ EGAL+E Sbjct: 93 GKTCGHCEFCKTGRYNLCPDVIFFATPPVDGVFQEYVAHEADLCFKLPENVSTLEGALIE 152 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PLAVG HA +GG G +V+G Sbjct: 153 PLAVGFHAAIQGGARIGQTAVVMG 176 Score = 102 bits (244), Expect = 9e-21 Identities = 40/80 (50%), Positives = 62/80 (77%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 L++ IP + E+EVL+++D VGICGSD+HY++ G+ G +++E P ++GHE GVV ++G+ Sbjct: 18 LIERDIPIVKENEVLVKLDYVGICGSDLHYYENGRIGDYIVEPPFVLGHEPGGVVVEVGN 77 Query: 213 KVKNLTVGDRVAIEPACRVG 272 KVK+L +GDRVA+EP G Sbjct: 78 KVKHLNIGDRVALEPGKTCG 97 >UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5; Actinomycetales|Rep: Zinc-binding dehydrogenase - Janibacter sp. HTCC2649 Length = 355 Score = 116 bits (279), Expect = 5e-25 Identities = 51/91 (56%), Positives = 62/91 (68%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C C G Y+LCPDM+F ATPP+ G L Y H + F F LPD V+++EGA+LE Sbjct: 98 GVPCRSCAQCLAGHYNLCPDMVFHATPPIDGTLAEYVVHPSSFAFALPDSVSLDEGAMLE 157 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 PL+VGI AC+R GV+ G VLV G P L Sbjct: 158 PLSVGIWACRRAGVAPGVRVLVTGAGPVGQL 188 Score = 88.6 bits (210), Expect = 1e-16 Identities = 38/90 (42%), Positives = 59/90 (65%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L +P + + P+P + DEVL+ + VG+CGSD HY+ G+ G ++ PM++GHE Sbjct: 13 AVLAEPGSIVMETRPVPSPAADEVLIEVRSVGVCGSDTHYFDHGRIGEHIVTGPMVLGHE 72 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 ++GV+ +GS V +G+RVAIEP CR Sbjct: 73 SAGVIVGVGSGVDPARIGERVAIEPGVPCR 102 >UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx mori|Rep: Sorbitol dehydrogenase - Bombyx mori (Silk moth) Length = 348 Score = 116 bits (279), Expect = 5e-25 Identities = 49/101 (48%), Positives = 67/101 (66%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 PCR CE CK G+Y+LC + +C++ GNL RYYKH ADFC KLPD++TMEEGA ++PL Sbjct: 94 PCRSCELCKRGKYNLCVEPRYCSSMGAPGNLCRYYKHVADFCHKLPDNLTMEEGAAVQPL 153 Query: 443 AVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 A+ IHAC R ++ G +++LG P L K + +K Sbjct: 154 AIVIHACNRAKITLGSKIVILGAGPIGILCAMSAKAMGASK 194 Score = 114 bits (275), Expect = 2e-24 Identities = 49/90 (54%), Positives = 70/90 (77%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L+ ND+R+ + P+PEI++DEVL+++DCVGICGSDV + G CG V+++P+++GHE Sbjct: 7 AVLHGANDVRIEKIPVPEINDDEVLIKIDCVGICGSDVKLYSTGTCGADVIDKPIVIGHE 66 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 +G V K+G KV +L VGDRVAIEP CR Sbjct: 67 GAGTVVKVGDKVSSLRVGDRVAIEPTQPCR 96 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/43 (48%), Positives = 31/43 (72%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AKA GA K+++ D++QSRLD A LGAD LL+ ++ + E+V Sbjct: 187 AKAMGASKIILTDVVQSRLDAALELGADNVLLVRREYTDEEVV 229 >UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=41; Magnoliophyta|Rep: Sorbitol dehydrogenase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 364 Score = 115 bits (276), Expect = 1e-24 Identities = 48/87 (55%), Positives = 62/87 (71%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+ C C C+ GRY+LCP+M F ATPPVHG+L H AD CFKLP++V++EEGA+ E Sbjct: 106 GISCWRCNLCREGRYNLCPEMKFFATPPVHGSLANQVVHPADLCFKLPENVSLEEGAMCE 165 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VG+HAC+R V VLV+G P Sbjct: 166 PLSVGVHACRRAEVGPETNVLVMGAGP 192 Score = 92.3 bits (219), Expect = 1e-17 Identities = 38/79 (48%), Positives = 57/79 (72%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 N L++ +P + +V +RM VGICGSDVHY + C FV++EPM++GHE +G++ Sbjct: 27 NTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMICADFVVKEPMVIGHECAGIIE 86 Query: 201 KIGSKVKNLTVGDRVAIEP 257 ++G +VK+L VGDRVA+EP Sbjct: 87 EVGEEVKHLVVGDRVALEP 105 >UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22; Ascomycota|Rep: Xylitol dehydrogenase - Aspergillus clavatus Length = 380 Score = 111 bits (268), Expect = 1e-23 Identities = 45/94 (47%), Positives = 62/94 (65%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR CE CK G+Y+LC M F ATPP G L +YY DFC+KLP++++++EGAL+E Sbjct: 121 GVPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKYYPLPEDFCYKLPENISLQEGALME 180 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCS 538 PL V +H ++ + G V+V G P L C+ Sbjct: 181 PLGVAVHITRQASIKPGESVVVFGAGPVGLLCCA 214 Score = 103 bits (246), Expect = 5e-21 Identities = 45/85 (52%), Positives = 64/85 (75%), Gaps = 3/85 (3%) Frame = +3 Query: 21 NDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 + ++ PIPE+ + +V++ + GICGSDVHYW+ G GHFV+++PM++GHE+SGVV Sbjct: 41 HQVKFEDRPIPELRDPHDVIVNVKYTGICGSDVHYWEHGAIGHFVVKDPMVLGHESSGVV 100 Query: 198 AKIGSKVKNLTVGDRVAIEPA--CR 266 AK+GS V +L VGDRVA+EP CR Sbjct: 101 AKVGSAVTSLKVGDRVAMEPGVPCR 125 Score = 36.3 bits (80), Expect = 0.67 Identities = 15/27 (55%), Positives = 21/27 (77%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGA 621 A+AFGA K++ +DI ++RLDFAK A Sbjct: 216 ARAFGASKIIAVDIQKTRLDFAKKYAA 242 >UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1; Deinococcus geothermalis DSM 11300|Rep: Alcohol dehydrogenase GroES-like - Deinococcus geothermalis (strain DSM 11300) Length = 359 Score = 111 bits (266), Expect = 2e-23 Identities = 51/87 (58%), Positives = 57/87 (65%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C FCK G Y+LCPDM F ATPPVHG L Y DF F LPD ++ + GALLE Sbjct: 98 GVPCRRCAFCKRGEYNLCPDMTFMATPPVHGALGEYVLWPDDFAFLLPDRISDDAGALLE 157 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PLAVGI A ++G V G V V G P Sbjct: 158 PLAVGIWAARKGDVRPGQSVAVFGAGP 184 Score = 84.2 bits (199), Expect = 3e-15 Identities = 41/90 (45%), Positives = 57/90 (63%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 ++L+ DLR +P EV +R+ VG+CGSDVHY+ G+ G FV+E P+I+GHE Sbjct: 13 SVLHGIRDLRWETREVPAPGPREVRVRVRRVGVCGSDVHYYTHGRIGSFVVEAPLILGHE 72 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 GVV +G V ++ GDRVA+EP CR Sbjct: 73 VMGVVDAVGEGVTHVRPGDRVALEPGVPCR 102 >UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1; Haloarcula marismortui|Rep: Zinc-binding dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 343 Score = 106 bits (255), Expect = 4e-22 Identities = 47/87 (54%), Positives = 54/87 (62%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C CK G YHLC + F ATPP G Y ADF + LP+ V+ EGAL E Sbjct: 89 GVPCRRCAHCKRGDYHLCESVRFMATPPHDGAFTEYVSWPADFAYTLPESVSTAEGALCE 148 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VGIHAC+RG V G VL+ G P Sbjct: 149 PLSVGIHACRRGSVGTGDTVLITGAGP 175 Score = 92.3 bits (219), Expect = 1e-17 Identities = 41/90 (45%), Positives = 61/90 (67%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L +P + L P P DEVL+ + VGICGSDVHY++ G+ G +V+E+P+++GHE Sbjct: 4 AVLVEPTEFELEDRPRPSPGPDEVLVAVRDVGICGSDVHYYEHGRIGDYVVEDPLVLGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 ++G V ++G V + GDRVA+EP CR Sbjct: 64 SAGKVVEVGENVTDHEPGDRVALEPGVPCR 93 >UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8; Pezizomycotina|Rep: Xylitol dehydrogenase - Aspergillus fumigatus (Sartorya fumigata) Length = 383 Score = 105 bits (252), Expect = 1e-21 Identities = 42/94 (44%), Positives = 61/94 (64%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+ C C++C++G Y+LC M+F ATPP G L +YK A+ C+KLP H+++ +GAL+E Sbjct: 117 GISCNTCKYCRSGHYNLCKSMVFAATPPYDGTLSTFYKVPAECCYKLPVHISLRDGALVE 176 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCS 538 PL+V +HAC+ G V+V G P L CS Sbjct: 177 PLSVAVHACRLAGDMQNKSVVVFGAGPVGLLCCS 210 Score = 95.1 bits (226), Expect = 1e-18 Identities = 45/108 (41%), Positives = 62/108 (57%), Gaps = 1/108 (0%) Frame = +3 Query: 39 QTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 215 + P P+I SE +V++R+ G+CGSDVHYWQ G+ G + + P+++GHE+SGV+ GS Sbjct: 43 ERPTPKIESERDVIVRVVATGLCGSDVHYWQHGRIGRYAVNRPIVLGHESSGVIVACGSN 102 Query: 216 VKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT*SSAPRPQYTETSS 359 V L VGDRVA+EP T R + A P Y T S Sbjct: 103 VDGLKVGDRVALEPGISCNTCKYCRSGHYNLCKSMVFAATPPYDGTLS 150 >UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1; Schizosaccharomyces pombe|Rep: Putative sorbitol dehydrogenase - Schizosaccharomyces pombe (Fission yeast) Length = 360 Score = 105 bits (252), Expect = 1e-21 Identities = 44/84 (52%), Positives = 57/84 (67%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G CR C++C++GRY+LCP M F ATPP G L YY DFC KLP +++EEGAL E Sbjct: 94 GCVCRLCDYCRSGRYNLCPHMEFAATPPYDGTLRTYYITTEDFCTKLPKQISVEEGALFE 153 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 P++V +HA RG + G VLV+G Sbjct: 154 PMSVAVHAMTRGNLKCGSRVLVMG 177 Score = 89.4 bits (212), Expect = 7e-17 Identities = 39/87 (44%), Positives = 59/87 (67%), Gaps = 1/87 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L K D + P +++D +V + + GICGSDVHYW++G G F+L++PMI+GHE Sbjct: 9 VLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFILKKPMILGHE 68 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPAC 263 ++GVV ++G V +L GD VA+EP C Sbjct: 69 SAGVVVEVGKGVSSLKPGDPVAVEPGC 95 >UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|Rep: Alcohol dehydrogenase - Aedes aegypti (Yellowfever mosquito) Length = 364 Score = 105 bits (251), Expect = 1e-21 Identities = 50/90 (55%), Positives = 68/90 (75%), Gaps = 2/90 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 AL+Y PNDLRL PIPE + +EV++ +D GICG+D+H+ + G G L +P+++GHE Sbjct: 10 ALVYGPNDLRLEPRPIPEPAFNEVVVEVDSCGICGTDIHFLKDGGFGAQRLIKPIVLGHE 69 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 ++GVV K+GS+V NL VGDRVAIEPA CR Sbjct: 70 SAGVVRKVGSQVTNLKVGDRVAIEPAAGCR 99 Score = 100 bits (239), Expect = 4e-20 Identities = 42/84 (50%), Positives = 55/84 (65%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 CR C+ CK G+Y++C D C T GN YY AD CFK+PDH+TMEEGALLEPLA Sbjct: 98 CRTCDLCKVGKYNICLDGKHCTTQKHDGNCSNYYAQYADCCFKMPDHMTMEEGALLEPLA 157 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 V ++A +R + G+ V++ G P Sbjct: 158 VAVYAGRRAQIGLGNKVVIFGAGP 181 >UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5; Bacillales|Rep: Sorbitol dehydrogenase - Bacillus subtilis Length = 353 Score = 103 bits (248), Expect = 3e-21 Identities = 40/97 (41%), Positives = 68/97 (70%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+++ ++++ P+P+I+ DEVL+++ VGICGSD+HY+ G+ G++V+E+P I+GHE Sbjct: 12 AVMHNTREIKIETLPVPDINHDEVLIKVMAVGICGSDLHYYTNGRIGNYVVEKPFILGHE 71 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 +G +A +GS V VGDRVA+EP G + ++ Sbjct: 72 CAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKE 108 Score = 101 bits (241), Expect = 2e-20 Identities = 44/87 (50%), Positives = 56/87 (64%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GV C CE CK GRY+LCPD+ F ATPPV G V+Y K DF F +PD ++ EE AL+E Sbjct: 97 GVTCGRCEACKEGRYNLCPDVQFLATPPVDGAFVQYIKMRQDFVFLIPDSLSYEEAALIE 156 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P +VGIHA R + G + ++G P Sbjct: 157 PFSVGIHAAARTKLQPGSTIAIMGMGP 183 >UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8; Saccharomycetales|Rep: Sorbitol dehydrogenase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 357 Score = 100 bits (239), Expect = 4e-20 Identities = 46/87 (52%), Positives = 57/87 (65%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVP RY + K G Y+LCP M F ATPP+ G LV+YY DF KLP+ V+ EEGA +E Sbjct: 95 GVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVKLPEGVSYEEGACVE 154 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VG+H+ K GV G V+V G P Sbjct: 155 PLSVGVHSNKLAGVRFGTKVVVFGAGP 181 Score = 89.8 bits (213), Expect = 5e-17 Identities = 40/85 (47%), Positives = 57/85 (67%), Gaps = 1/85 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L K D+ + Q PIP I + V L + GICGSD+HY++ G G ++L+ PM++GHE Sbjct: 10 VLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHE 69 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 +SG V ++G V + VGDRVAIEP Sbjct: 70 SSGQVVEVGDAVTRVKVGDRVAIEP 94 >UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1; Filobasidiella neoformans|Rep: Sorbitol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 379 Score = 98.3 bits (234), Expect = 1e-19 Identities = 48/92 (52%), Positives = 64/92 (69%), Gaps = 5/92 (5%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ D+R Q PIPE+ D+VL+++ GICGSDVHY Q G+ G FVLEEPM +GHE+ Sbjct: 13 VLHGVEDVRFDQRPIPEVHNDQVLIKVVKTGICGSDVHYLQHGRIGSFVLEEPMCLGHES 72 Query: 186 SGVVAKIGSKVK---NLTVGDRVAIEP--ACR 266 +GVV K+G V+ + VG RVA+EP CR Sbjct: 73 AGVVVKLGPNVREDLGVEVGTRVAMEPGVCCR 104 Score = 90.6 bits (215), Expect = 3e-17 Identities = 46/101 (45%), Positives = 58/101 (57%), Gaps = 2/101 (1%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPP-VHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 GV CR C CK G Y LCP M F ATPP + G L RYY AD LP+ V+ E+GA++ Sbjct: 100 GVCCRSCANCKAGLYELCPYMSFAATPPTIFGTLCRYYVLPADLVHPLPESVSFEDGAMM 159 Query: 434 EPLAVGIHA-CKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 EPL+VG+H+ GG + V+V G P L + K L Sbjct: 160 EPLSVGVHSVATLGGCKSDQTVIVFGAGPVGLLCMAVAKAL 200 Score = 33.5 bits (73), Expect = 4.7 Identities = 14/27 (51%), Positives = 20/27 (74%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGA 621 AKA GA +++ +DI + RL+FAKS A Sbjct: 197 AKALGARRIIAVDINKERLEFAKSYAA 223 >UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9; Ascomycota|Rep: Contig An08c0230, complete genome - Aspergillus niger Length = 387 Score = 98.3 bits (234), Expect = 1e-19 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 3/107 (2%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L+ D+ P+P + + +V + + GICGSDVHYWQ+G+ G F+L+ P+++GHE Sbjct: 39 VLHAIKDVVFEDRPVPALKDPWDVRVHIAQTGICGSDVHYWQRGRIGDFILKSPIVLGHE 98 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA--CRVGTASSVRQDDTTYALT 317 +SG V ++GS VKN+ VG+RVAIEP CR G+ + DT +A T Sbjct: 99 SSGTVVEVGSAVKNVKVGERVAIEPGVPCRHGSYNLC--PDTIFAAT 143 Score = 89.8 bits (213), Expect = 5e-17 Identities = 42/87 (48%), Positives = 55/87 (63%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR+ G Y+LCPD IF ATPP G L +YY AD+C+ LP+++ +EEGAL+E Sbjct: 124 GVPCRH------GSYNLCPDTIFAATPPHDGTLSKYYTTQADYCYPLPENMDLEEGALVE 177 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P+AV + K G V V+V G P Sbjct: 178 PVAVAVQITKVGKVKPNQTVVVFGCGP 204 Score = 37.1 bits (82), Expect = 0.38 Identities = 16/32 (50%), Positives = 23/32 (71%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLL 636 +KA+ A KV+ +DI QSR DFA + GAD+ + Sbjct: 213 SKAYSAKKVIGVDISQSRADFAHNFGADHVFV 244 >UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5; Trichocomaceae|Rep: L-arabinitol 4-dehydrogenase - Aspergillus fumigatus (Sartorya fumigata) Length = 359 Score = 97.9 bits (233), Expect = 2e-19 Identities = 40/89 (44%), Positives = 58/89 (65%), Gaps = 2/89 (2%) Frame = +2 Query: 257 GVPCRY--CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 GVPC C FC+TG+YH CPD++F +TPP HG L RY+ H + K+PD+++ EEG+L Sbjct: 98 GVPCSKPTCSFCRTGKYHACPDVVFFSTPPHHGTLRRYHAHPEAWLHKIPDNISFEEGSL 157 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 LEPL+V + R G+ +++ G P Sbjct: 158 LEPLSVALAGINRSGLRLADPLVICGAGP 186 Score = 81.8 bits (193), Expect = 1e-14 Identities = 36/78 (46%), Positives = 52/78 (66%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 +DLRLV+ IP++ DE L+ + GICGSDVH+W+ G+ G ++ +GHE++GVV Sbjct: 19 HDLRLVECEIPKLRPDECLVHVRATGICGSDVHFWKHGRIGPMIVTGDNGLGHESAGVVL 78 Query: 201 KIGSKVKNLTVGDRVAIE 254 +IG V GDRVA+E Sbjct: 79 QIGEAVTRFKPGDRVALE 96 >UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6; Basidiomycota|Rep: L-iditol 2-dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 400 Score = 94.7 bits (225), Expect = 2e-18 Identities = 43/89 (48%), Positives = 56/89 (62%), Gaps = 2/89 (2%) Frame = +2 Query: 257 GVPCRY--CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 GVPC C C TGRY+ CP ++F +TPP HG L RY+ H A + +LPD+++ EEGAL Sbjct: 141 GVPCGQASCGPCVTGRYNACPQVVFFSTPPYHGTLTRYHAHPASWLHRLPDNLSYEEGAL 200 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EP AV + A +R G G VL+ G P Sbjct: 201 CEPFAVALAALERAGNRLGDPVLICGAGP 229 Score = 80.2 bits (189), Expect = 4e-14 Identities = 36/88 (40%), Positives = 57/88 (64%), Gaps = 1/88 (1%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCG-HFVLEEPMIMGHEASGVV 197 ++++++ PIP+ +DEV++ + GICGSDVH+W+ GQ G ++ + GHE++G V Sbjct: 61 HNVKMINKPIPKARQDEVVVHIKATGICGSDVHFWKHGQIGPTMIVTDTCGAGHESAGEV 120 Query: 198 AKIGSKVKNLTVGDRVAIEPACRVGTAS 281 ++G V+ VGDRVAIE G AS Sbjct: 121 VEVGPGVEQWKVGDRVAIECGVPCGQAS 148 >UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=6; cellular organisms|Rep: Alcohol dehydrogenase, zinc-binding - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 348 Score = 94.3 bits (224), Expect = 2e-18 Identities = 42/85 (49%), Positives = 61/85 (71%), Gaps = 1/85 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPE-ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L K +L L +P+ + D+V +R+ VGICGSDVHY+ G+ G FV+ EPM++GHE Sbjct: 7 VLEKQRELSLRDIDLPDQLGPDDVRIRIHTVGICGSDVHYYTHGRIGPFVVREPMVLGHE 66 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 ASGV+ ++GS V +L VG+RV +EP Sbjct: 67 ASGVITEVGSHVSHLKVGERVCMEP 91 Score = 72.1 bits (169), Expect = 1e-11 Identities = 36/87 (41%), Positives = 48/87 (55%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+P K G Y++ P + F ATPPVHG L H A F F LPD V+ EGA++E Sbjct: 92 GIPDPTSRAAKLGVYNVDPGVRFWATPPVHGCLTPEVIHPAAFTFALPDSVSFAEGAMIE 151 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P A+G+ A + + G V +V G P Sbjct: 152 PFAIGMQAVVKARMQPGDVCVVTGAGP 178 >UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13; Alphaproteobacteria|Rep: L-idonate 5-dehydrogenase - Silicibacter pomeroyi Length = 349 Score = 93.5 bits (222), Expect = 4e-18 Identities = 44/102 (43%), Positives = 62/102 (60%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 ++ D+R+ P+PE +V++ M GICGSD+HY+ G G + EPMI+GHE + Sbjct: 8 IHAARDIRVETDPLPEPGPAQVIVAMAAAGICGSDLHYYHDGGFGPIRVREPMILGHEGA 67 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYAL 314 GVVA +G V L VGDRVA+ P+ GT S + TT+ L Sbjct: 68 GVVAALGPGVTGLAVGDRVAVNPSRPCGTCSYCVEGLTTHCL 109 Score = 53.6 bits (123), Expect = 4e-06 Identities = 37/90 (41%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATP---PVHGNLVR--YYKHAADFCFKLPDHVTMEEGA 427 PC C +C G C +M F + P L R AA C KL DHVT+ EGA Sbjct: 93 PCGTCSYCVEGLTTHCLNMRFYGSAMRFPHEQGLFRDKLLTDAAQ-CHKLSDHVTISEGA 151 Query: 428 LLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EPLAV +HA G G VLV G P Sbjct: 152 CAEPLAVCLHARHMAGEVRGKRVLVTGSGP 181 >UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Xanthobacter autotrophicus Py2|Rep: Alcohol dehydrogenase GroES domain protein - Xanthobacter sp. (strain Py2) Length = 345 Score = 92.7 bits (220), Expect = 7e-18 Identities = 40/86 (46%), Positives = 59/86 (68%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+++ DLRL + P PE++ +EVL+ GICGSD+ Y+ KG+ G F L +PM++GHE Sbjct: 4 AVIHAAKDLRLDECPEPEMAANEVLVSFRAGGICGSDLSYYGKGRVGDFALRQPMVLGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA 260 SG V K+G+ V L +GD VA+ P+ Sbjct: 64 ISGEVIKLGASVSTLALGDHVAVNPS 89 Score = 63.7 bits (148), Expect = 4e-09 Identities = 33/93 (35%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C++C+ GR +LC +M F + P V G + AD C +P + A+ Sbjct: 91 PCLECDYCRAGRSNLCRNMRFFGSAAIYPHVQGAFSETFVCRADQCVSVPRDIPFRRVAM 150 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EPL+V IH +R G AG VL+ G P L Sbjct: 151 AEPLSVAIHGVRRAGELAGKRVLIAGAGPIGML 183 >UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Rep: D-xylulose reductase - Morganella morganii (Proteus morganii) Length = 338 Score = 92.7 bits (220), Expect = 7e-18 Identities = 38/67 (56%), Positives = 53/67 (79%) Frame = +3 Query: 57 ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVG 236 + +D+V +++ VGICGSDVHY+Q G+ G FV++EPM++GHEASGV+ G VK+L VG Sbjct: 25 LGDDDVEIKIHTVGICGSDVHYYQHGRIGPFVVDEPMVLGHEASGVITAAGKNVKHLKVG 84 Query: 237 DRVAIEP 257 DRV +EP Sbjct: 85 DRVCMEP 91 Score = 72.9 bits (171), Expect = 6e-12 Identities = 34/84 (40%), Positives = 51/84 (60%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+P + G Y+L P + F ATPP+ G L H A F FKLPD+V+ +GA++E Sbjct: 92 GIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFKLPDNVSFAQGAMVE 151 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PLA+G+ + + G+ G + LV+G Sbjct: 152 PLAIGMQSATKAGIKPGDIGLVIG 175 >UniRef50_P22144 Cluster: D-xylulose reductase; n=8; Saccharomycetales|Rep: D-xylulose reductase - Pichia stipitis (Yeast) Length = 363 Score = 92.7 bits (220), Expect = 7e-18 Identities = 47/104 (45%), Positives = 61/104 (58%), Gaps = 7/104 (6%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVH-------GNLVRYYKHAADFCFKLPDHVTM 415 G+P R+ + K+G Y+LCP M F ATP G L +Y+K DF KLPDHV++ Sbjct: 93 GIPSRFSDEYKSGHYNLCPHMAFAATPNSKEGEPNPPGTLCKYFKSPEDFLVKLPDHVSL 152 Query: 416 EEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 E GAL+EPL+VG+HA K G V+ G V V G P L + K Sbjct: 153 ELGALVEPLSVGVHASKLGSVAFGDYVAVFGAGPVGLLAAAVAK 196 Score = 87.4 bits (207), Expect = 3e-16 Identities = 40/85 (47%), Positives = 60/85 (70%), Gaps = 1/85 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L K +D+ PEISE +VL+++ GICGSD+H++ G+ G+FVL +PM++GHE Sbjct: 8 VLNKIDDISFETYDAPEISEPTDVLVQVKKTGICGSDIHFYAHGRIGNFVLTKPMVLGHE 67 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 ++G V ++G V +L VGD VAIEP Sbjct: 68 SAGTVVQVGKGVTSLKVGDNVAIEP 92 Score = 34.7 bits (76), Expect = 2.0 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AK FGA V+++DI ++L AK +GA K EL+ Sbjct: 195 AKTFGAKGVIVVDIFDNKLKMAKDIGAATHTFNSKTGGSEELI 237 >UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain protein; n=4; Actinomycetales|Rep: Alcohol dehydrogenase GroES domain protein - Mycobacterium sp. (strain JLS) Length = 341 Score = 91.9 bits (218), Expect = 1e-17 Identities = 40/77 (51%), Positives = 55/77 (71%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 LR+ + P+P EVL+ + VG+CGSDVHY++ G+ G FV+EEPMI+GHE SG +A + Sbjct: 20 LRIEERPVPSPGPHEVLVEVAAVGVCGSDVHYYRHGRIGDFVVEEPMILGHELSGRIAAV 79 Query: 207 GSKVKNLTVGDRVAIEP 257 G V VG+RVA+EP Sbjct: 80 GEGVDPGRVGERVAVEP 96 Score = 87.8 bits (208), Expect = 2e-16 Identities = 40/93 (43%), Positives = 56/93 (60%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 PCR C+ CK GRY+LCP+M F ATPP+ G RY DF +P+ ++ + ALLEPL Sbjct: 99 PCRRCKQCKAGRYNLCPEMKFYATPPIDGAFCRYVVIDDDFAHPVPESMSDDAAALLEPL 158 Query: 443 AVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQ 541 +V I ++ GV G +L+ G P + C+Q Sbjct: 159 SVAIATMRKAGVVPGSTILIAGAGPIGVI-CAQ 190 >UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3; Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 386 Score = 91.9 bits (218), Expect = 1e-17 Identities = 40/86 (46%), Positives = 57/86 (66%), Gaps = 2/86 (2%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPP-VHGNLVRYYKHAADFCFKL-PDHVTMEEGAL 430 G PC C CK+GRY+LCP M F A PP HG L +Y++ AD+C+K+ P + ++E L Sbjct: 101 GYPCHRCPCCKSGRYNLCPRMKFAAAPPSCHGTLTKYFRLPADYCYKIPPGTLGLDEAVL 160 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLG 508 +EPLAV +H+ ++ GV G V+V G Sbjct: 161 MEPLAVAVHSVRQVGVRPGDRVVVFG 186 Score = 87.4 bits (207), Expect = 3e-16 Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 2/86 (2%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFV-LEEPMIMGH 179 LLY P D R PIP+I + +V++R+ G+CGSDVH+W G V E P++MGH Sbjct: 15 LLYGPFDARFEDRPIPQIEDPSDVIIRIAYTGVCGSDVHFWLHGGVKRLVSAEHPIVMGH 74 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 EASG+V +G V L GD +AIEP Sbjct: 75 EASGIVHAVGPSVSTLQPGDHIAIEP 100 >UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1; Bradyrhizobium japonicum|Rep: L-idonate 5-dehydrogenase - Bradyrhizobium japonicum Length = 349 Score = 91.5 bits (217), Expect = 2e-17 Identities = 39/97 (40%), Positives = 62/97 (63%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A L+ P DLR+++ P+ +++ V +R GICGSD+HY++ + G FV++ P+++GHE Sbjct: 8 ATLFGPEDLRMIEHPLDKLASGMVRIRFGAGGICGSDMHYFRHARTGDFVVKSPLVLGHE 67 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 SG V +I NL VGDRVA+ P+ G + R+ Sbjct: 68 ISGEVVEISGSAANLKVGDRVAVNPSRWCGHCVACRE 104 Score = 65.3 bits (152), Expect = 1e-09 Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCA----TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 C +C C+ GR +LC ++ F TP + G Y+ C K+PDHV+ + AL Sbjct: 96 CGHCVACREGRPNLCENIYFMGSASKTPHMQGGFANYFDAIPAQCVKIPDHVSYQAAALA 155 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EPLAV +HA R G G ++ G P Sbjct: 156 EPLAVCLHAVARAGNIEGKRGIIFGAGP 183 >UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 382 Score = 89.8 bits (213), Expect = 5e-17 Identities = 41/89 (46%), Positives = 59/89 (66%), Gaps = 2/89 (2%) Frame = +2 Query: 257 GVPC--RYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 GVPC C+FC+TG+Y+LCP + F + PP G L RY++H A + K+PD+++ EE AL Sbjct: 107 GVPCFKATCDFCRTGKYNLCPTVDFYSVPPKDGTLKRYHEHPAGWLHKVPDNMSYEEIAL 166 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 LEPL+V + A + +S G VL+ G P Sbjct: 167 LEPLSVTLQATLQAEISLGTPVLITGAGP 195 Score = 68.1 bits (159), Expect = 2e-10 Identities = 29/78 (37%), Positives = 45/78 (57%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 +L L+++ L+ + G+CGSDVH+W+ G + +E +GHE+ G+V Sbjct: 29 ELELIKSTPAAPGPGMALVHVRATGVCGSDVHFWKHAGLGPWKIESQCALGHESGGIVIA 88 Query: 204 IGSKVKNLTVGDRVAIEP 257 +G V N+ GDRVAIEP Sbjct: 89 VGEGVDNVVPGDRVAIEP 106 >UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 377 Score = 89.8 bits (213), Expect = 5e-17 Identities = 40/90 (44%), Positives = 56/90 (62%), Gaps = 6/90 (6%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCA------TPPVHGNLVRYYKHAADFCFKLPDHVTME 418 G PCR C CK+G Y+LC M+F A TP G L ++Y+ A D C+ +PD ++++ Sbjct: 102 GTPCRRCAACKSGTYNLCRHMLFAAAPGPPSTPGTPGTLSKFYEMAEDLCYVIPDAISLQ 161 Query: 419 EGALLEPLAVGIHACKRGGVSAGHVVLVLG 508 E L+EPLAV +HA K G V G V+V+G Sbjct: 162 EAVLVEPLAVAVHAVKLGDVRPGETVVVMG 191 Score = 80.2 bits (189), Expect = 4e-14 Identities = 44/118 (37%), Positives = 67/118 (56%), Gaps = 4/118 (3%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-MIMGH 179 +LY + +L + P+PE+S+ + V++R+ VG+CGSDVH++ G G V + MGH Sbjct: 16 VLYGAKNAKLEERPVPELSDPNNVIVRIAYVGVCGSDVHFYTHGGIGRSVDPSTGLTMGH 75 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEPA--CRVGTASSVRQDDTTYALT*SSAPRPQYT 347 EASG + +G V + +GDRVAIEP CR A + + ++AP P T Sbjct: 76 EASGTITSVGPSVTSFKIGDRVAIEPGTPCRRCAACKSGTYNLCRHMLFAAAPGPPST 133 >UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol dehydrogenase-like protein ydjJ; n=16; Bacteria|Rep: Uncharacterized zinc-type alcohol dehydrogenase-like protein ydjJ - Escherichia coli (strain K12) Length = 347 Score = 89.8 bits (213), Expect = 5e-17 Identities = 39/85 (45%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVH-GNLVRYYKHAADFCFKLPDHVTMEEGALL 433 GVPC +C +C G+Y++CPD+ F AT P + G L Y H F +KLPD++ EGAL+ Sbjct: 92 GVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALV 151 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLG 508 EP AVG+HA V G +++LG Sbjct: 152 EPAAVGMHAAMLADVKPGKKIIILG 176 Score = 72.9 bits (171), Expect = 6e-12 Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 1/91 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQ-CGHFVLEEPMIMGH 179 A+L P ++++ IP EDEVL++++ VGICGSDVH ++ G + + +GH Sbjct: 6 AILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGH 65 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 E +G V +GS+V+ GDRV IEP G Sbjct: 66 ECAGTVVAVGSRVRKFKPGDRVNIEPGVPCG 96 >UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus clausii KSM-K16|Rep: Sorbitol dehydrogenase - Bacillus clausii (strain KSM-K16) Length = 346 Score = 89.0 bits (211), Expect = 9e-17 Identities = 40/88 (45%), Positives = 56/88 (63%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 + L + P+ EVL++M VGICGSD+HY++ G+ G V + P ++GHE +GVV K+ Sbjct: 12 IELEERTKPKPGAGEVLIQMKAVGICGSDLHYYEHGRIGERVAKPPFVLGHECAGVVTKV 71 Query: 207 GSKVKNLTVGDRVAIEPACRVGTASSVR 290 G +V +L VGD V IEP G SS R Sbjct: 72 GPEVADLNVGDHVVIEPGLPCGECSSCR 99 Score = 83.4 bits (197), Expect = 4e-15 Identities = 31/87 (35%), Positives = 55/87 (63%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+PC C C+ G Y+LCP ++F ++PP G L+ Y H A F +K+P+ ++ E +L E Sbjct: 89 GLPCGECSSCRVGHYNLCPKVLFLSSPPNDGVLMEYICHPAKFTYKMPEGLSFELASLAE 148 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+VG++ ++ + G ++++G P Sbjct: 149 PLSVGLYTAQKTSIQPGSNIVIMGMGP 175 Score = 33.1 bits (72), Expect = 6.2 Identities = 15/43 (34%), Positives = 27/43 (62%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AK +GA +++ DI RL+ AK +GA T+ + +++ A L+ Sbjct: 184 AKWYGASNIVVTDIEPYRLEIAKKIGAMDTIQVNHEADRAGLL 226 >UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 387 Score = 87.0 bits (206), Expect = 4e-16 Identities = 42/98 (42%), Positives = 56/98 (57%), Gaps = 1/98 (1%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPCR C+ C G Y+ C + F ATPP G L YY + F +PDH+++EE +L+E Sbjct: 107 GVPCRSCQVCLNGMYNQCAHLEFAATPPYDGTLCTYYNIQSSFAHHVPDHMSLEEASLME 166 Query: 437 PLAVGIH-ACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 PL+V ++ A RG V A VLV G P L + K Sbjct: 167 PLSVAVYSAGMRGQVKAMENVLVFGAGPIGLLNAAVCK 204 Score = 72.1 bits (169), Expect = 1e-11 Identities = 33/78 (42%), Positives = 47/78 (60%), Gaps = 2/78 (2%) Frame = +3 Query: 39 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 218 + PI +V + + G+C SD HY G+ G FV+ +PM++GHE+SG+V +G V Sbjct: 34 ERPIVAPKPGQVQVNIRQTGLCASDCHYLHHGRIGDFVVRKPMVLGHESSGIVTAVGEGV 93 Query: 219 KNLTVGDRVAIEPA--CR 266 VGDRVA+EP CR Sbjct: 94 TTHKVGDRVALEPGVPCR 111 >UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1; Filobasidiella neoformans|Rep: Sorbitol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 416 Score = 85.8 bits (203), Expect = 8e-16 Identities = 45/101 (44%), Positives = 56/101 (55%), Gaps = 2/101 (1%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPP-VHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 GV CR C CK G+Y +C MIF A PP G L RYY AD + LPD+V + GA++ Sbjct: 138 GVTCRMCVDCKGGKYQICEHMIFAAYPPSTGGTLQRYYALPADLVYPLPDNVDLSFGAMM 197 Query: 434 EPLAVGIHACKR-GGVSAGHVVLVLGRDPSASLPCSQLKPL 553 EPL+V HA GG+ G VL+ G P L + K L Sbjct: 198 EPLSVATHAVANIGGMRTGWNVLITGAGPVGLLAMAVAKGL 238 Score = 70.9 bits (166), Expect = 3e-11 Identities = 30/71 (42%), Positives = 45/71 (63%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ P + +PEI DEVL+ + GICGSDVH++ G+ G L E M +GHE+ Sbjct: 27 MLHSPLKTSFEEQSVPEIGPDEVLVEIKKTGICGSDVHFYNTGKMGLAALTESMCLGHES 86 Query: 186 SGVVAKIGSKV 218 SG+V ++GS + Sbjct: 87 SGIVVQLGSNI 97 >UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 320 Score = 85.4 bits (202), Expect = 1e-15 Identities = 39/87 (44%), Positives = 50/87 (57%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPC C C GRY+LC D+ F P G + RY H A +C LP +V+ EGALLE Sbjct: 78 GVPCETCFLCMDGRYNLCEDVKFSGVYPDAGTIQRYKTHPARWCHILPSNVSYSEGALLE 137 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+V +H K G+S G ++ G P Sbjct: 138 PLSVVMHGIKSAGLSLGRGAVICGAGP 164 Score = 62.5 bits (145), Expect = 9e-09 Identities = 26/50 (52%), Positives = 37/50 (74%) Frame = +3 Query: 108 SDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEP 257 SD+H+W++G+ G V+E I+GHEA+GVV + G V +L GDRVA+EP Sbjct: 28 SDIHFWKRGRIGSLVVEGDCILGHEAAGVVLECGEGVISLKPGDRVAVEP 77 >UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7; Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 385 Score = 85.4 bits (202), Expect = 1e-15 Identities = 42/106 (39%), Positives = 63/106 (59%), Gaps = 4/106 (3%) Frame = +2 Query: 254 AGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEE 421 +GV C C+ C++GRY++C M F ++ P G L Y H A++C KLPD ++ ++ Sbjct: 98 SGVACLECDKCRSGRYNICAKMRFRSSGASFPHFQGTLQEYVDHPAEWCHKLPDALSYDD 157 Query: 422 GALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEH 559 GALLEPL+V IH+ R GV G +V G + L C+ + +EH Sbjct: 158 GALLEPLSVCIHSVNRAGVDQGARCVVFGAG-AVGLLCAAVAKIEH 202 Score = 66.1 bits (154), Expect = 7e-10 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 3/85 (3%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 L+ P LRL P+ I +V +R+ +CGSDVHY++ + G ++EP+ GHEA+ Sbjct: 13 LHGPQQLRLEARPMTSIGPSDVRIRVRSTTLCGSDVHYFKFHRNGSIEVKEPLCGGHEAA 72 Query: 189 GVVAKIGS---KVKNLTVGDRVAIE 254 G V ++G K + + VGD VAIE Sbjct: 73 GEVVEVGPTVLKTQAIRVGDIVAIE 97 >UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) = L-sorbose + NADH; n=8; Eurotiomycetidae|Rep: Catalytic activity: L-iditol + NAD(+) = L-sorbose + NADH - Aspergillus niger Length = 405 Score = 83.4 bits (197), Expect = 4e-15 Identities = 37/83 (44%), Positives = 54/83 (65%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ DLRL P+ + EV + + G+CGSD+HY+ G+ G FV+ EPM +GHE+ Sbjct: 13 VLHGAKDLRLESRPLSPPTGSEVQVAIRATGLCGSDLHYYTHGRNGDFVVREPMCLGHES 72 Query: 186 SGVVAKIGSKVKNLTVGDRVAIE 254 SG++ IG +V VGDRVA+E Sbjct: 73 SGIITAIGPEVTTHAVGDRVALE 95 Score = 77.8 bits (183), Expect = 2e-13 Identities = 35/75 (46%), Positives = 47/75 (62%), Gaps = 4/75 (5%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 G+PCR C C+ GRY++CP M F ++ P + G L+ H A C KLP HV+ G Sbjct: 97 GLPCRQCALCQQGRYNICPQMKFRSSAKLFPHLDGTLMERTNHPASLCHKLPSHVSYAGG 156 Query: 425 ALLEPLAVGIHACKR 469 AL+EPLAV +HA +R Sbjct: 157 ALVEPLAVCLHAIRR 171 >UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9; cellular organisms|Rep: Putative D-xylulose reductase - Rhizobium loti (Mesorhizobium loti) Length = 348 Score = 83.4 bits (197), Expect = 4e-15 Identities = 40/87 (45%), Positives = 53/87 (60%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVP K G Y++ PD+ F ATPPVHG L Y H A F +KLPD+V+ EGA++E Sbjct: 90 GVPNLSSRATKLGIYNVDPDVSFWATPPVHGVLAPYAVHPAAFTYKLPDNVSFAEGAMVE 149 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P A+G+ A R + G V +V+G P Sbjct: 150 PFAIGMQAASRARIVPGDVAVVVGCGP 176 Score = 82.2 bits (194), Expect = 1e-14 Identities = 35/85 (41%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +L K +L L + +P ++ D+V + + VG+CGSDVHY+ G G +V+ PM++GHE Sbjct: 5 VLEKKGELSLREIALPLDVGPDDVKIAIHTVGVCGSDVHYYTHGAIGSYVVRAPMVLGHE 64 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 A+G V + G+ V+ GDRV +EP Sbjct: 65 AAGTVVETGANVETFKAGDRVCMEP 89 >UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Verminephrobacter eiseniae EF01-2|Rep: Alcohol dehydrogenase GroES domain protein - Verminephrobacter eiseniae (strain EF01-2) Length = 345 Score = 83.0 bits (196), Expect = 6e-15 Identities = 37/94 (39%), Positives = 57/94 (60%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 ++ DLR+ P ++ +V + + VGICGSD+HY+Q G+ G FV+ P+ GHEAS Sbjct: 6 IHGARDLRIADRPAEPLAAHQVRVGVKAVGICGSDLHYYQHGRVGDFVIRAPLTPGHEAS 65 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 G V ++G++V+ L G RVA+ P+ G R Sbjct: 66 GQVLELGAQVQGLQPGQRVALNPSRSCGVCRFCR 99 Score = 52.4 bits (120), Expect = 1e-05 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 4/92 (4%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 C C FC+ G + C ++ F + P + G + A C +PD ++ E A Sbjct: 92 CGVCRFCRAGAANHCENVHFFGSASKWPHMQGAMREQVVLDAAQCIAVPDALSYEVAAFG 151 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EPLAV +HA ++ G G V+V+G P +L Sbjct: 152 EPLAVALHAVRQAGSLLGKSVMVVGAGPIGAL 183 >UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Sorbitol dehydrogenase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 345 Score = 82.6 bits (195), Expect = 8e-15 Identities = 34/96 (35%), Positives = 58/96 (60%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L +P + + P+PE+ + +VL++++ VGICGSD+H + G G VL++P+++GHE Sbjct: 4 AVLMEPKKIIFKEVPVPELEKGKVLIKVEAVGICGSDMHLYLDGHIGATVLDKPLVLGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 G V ++G V +G RV ++P G R Sbjct: 64 IVGTVIEVGEGVNRELLGQRVIVDPGENCGQCEHCR 99 Score = 64.5 bits (150), Expect = 2e-09 Identities = 32/87 (36%), Positives = 41/87 (47%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G C CE C+TG Y+LC F PPV G + Y A LP+++ LLE Sbjct: 89 GENCGQCEHCRTGAYNLCSFSKFKGIPPVDGGMAEYITALATHVIPLPENLDSPTATLLE 148 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P +VG+ A AG + VLG P Sbjct: 149 PFSVGLQAVDVADFRAGAKIAVLGGGP 175 >UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 288 Score = 82.2 bits (194), Expect = 1e-14 Identities = 35/75 (46%), Positives = 55/75 (73%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 +VQ +P I +D+VL+++ G+CG+D+HY + G F+ + P+I GHEA+G +A IG+ Sbjct: 35 VVQIDVPSIGDDDVLVKISACGVCGTDLHYHK----GEFLAKWPLIPGHEAAGTIAAIGA 90 Query: 213 KVKNLTVGDRVAIEP 257 VKN++VGDRVA +P Sbjct: 91 NVKNVSVGDRVAADP 105 >UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <=> L-sorbose + NADH; n=1; Aspergillus niger|Rep: Catalytic activity: L-iditol + NAD(+) <=> L-sorbose + NADH - Aspergillus niger Length = 159 Score = 81.8 bits (193), Expect = 1e-14 Identities = 33/71 (46%), Positives = 49/71 (69%), Gaps = 1/71 (1%) Frame = +3 Query: 48 IPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 224 IP I D +VL+R+ G+CGSD+HYWQ G+ G + + +P+I+ HE+SGV+ G + Sbjct: 27 IPTIESDRDVLVRVVATGLCGSDIHYWQHGKLGEYEVTQPLILAHESSGVIVATGGNFQG 86 Query: 225 LTVGDRVAIEP 257 L + DRVA+EP Sbjct: 87 LKINDRVALEP 97 >UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=17; Proteobacteria|Rep: Zinc-containing alcohol dehydrogenase superfamily - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 352 Score = 81.4 bits (192), Expect = 2e-14 Identities = 35/85 (41%), Positives = 57/85 (67%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ PNDLR+ + EI +V + + GICGSD+HY++ G G L++PM++GHE Sbjct: 9 VIHGPNDLRVEEQDAGEIGPGQVRVDVAMGGICGSDLHYFRHGGFGAIRLQQPMVLGHEV 68 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPA 260 +G VA++ V ++ VGDRVA+ P+ Sbjct: 69 AGTVAEVAPDVTSVKVGDRVAVNPS 93 Score = 57.2 bits (132), Expect = 3e-07 Identities = 35/89 (39%), Positives = 41/89 (46%), Gaps = 4/89 (4%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C +C G + C DM F + P V G A C K+ DHV + AL Sbjct: 95 PCGACRYCLEGLPNQCLDMRFYGSAMRMPHVQGAFRNALVCDAVQCVKVADHVPLSLAAL 154 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EP AVG+HA R G G VLV G P Sbjct: 155 AEPFAVGLHAVSRAGPLIGKRVLVSGCGP 183 >UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain protein; n=3; Actinomycetales|Rep: Alcohol dehydrogenase GroES domain protein - Kineococcus radiotolerans SRS30216 Length = 349 Score = 81.4 bits (192), Expect = 2e-14 Identities = 37/89 (41%), Positives = 54/89 (60%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ DLR+ + P P+ EVLL ++ GICGSD+ YW+ G G LE P+++GHE Sbjct: 5 VVHGAGDLRVEERPDPQPGPGEVLLALEWGGICGSDLAYWRHGASGTAQLEHPLVLGHEV 64 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 +G VA +G V + VG V + PA VG Sbjct: 65 AGTVAALGPDVTGVEVGRAVTVHPATLVG 93 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Frame = +2 Query: 293 GRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 460 GR +L P + + + P G ++ +D LP+ V GAL EPLAV +HA Sbjct: 103 GRTNLWPQVRYFGSAAFDPHTDGGFSQFRTVRSDQLRFLPEGVDTLRGALAEPLAVAMHA 162 Query: 461 CKRGGVSAGHVVLVLGRDPSASL 529 R G AG VLV G P SL Sbjct: 163 VGRAGSLAGRDVLVNGAGPIGSL 185 >UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative; n=19; Ascomycota|Rep: Xylitol dehydrogenase XdhB, putative - Aspergillus clavatus Length = 386 Score = 81.4 bits (192), Expect = 2e-14 Identities = 39/84 (46%), Positives = 52/84 (61%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C CE C TGRY+ C + F +TPPV G L RY H A +C K+ D ++ E+GALLEPL+ Sbjct: 110 CNECEPCLTGRYNGCEKVAFLSTPPVDGLLRRYVNHPAIWCHKIGD-MSFEDGALLEPLS 168 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 V + A +R G+ G L+ G P Sbjct: 169 VSLAAIERSGLRLGDPCLITGAGP 192 Score = 69.3 bits (162), Expect = 8e-11 Identities = 31/63 (49%), Positives = 40/63 (63%) Frame = +3 Query: 69 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVA 248 EV + + GICGSDVH+W G G ++E I+GHE++G V + S V L GDRVA Sbjct: 44 EVTIEVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGQVIAVASDVTTLKPGDRVA 103 Query: 249 IEP 257 IEP Sbjct: 104 IEP 106 >UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8; Ascomycota|Rep: Sorbitol dehydrogenase - Aspergillus oryzae Length = 388 Score = 81.0 bits (191), Expect = 2e-14 Identities = 36/82 (43%), Positives = 50/82 (60%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 L+ + P+ EVLL++ GICGSD+H+W+ G G + + I+GHEA+GVV K Sbjct: 43 LKAIDAPVYAPKHGEVLLQIKATGICGSDLHFWKTGCIGELIFKGDCIIGHEAAGVVLKC 102 Query: 207 GSKVKNLTVGDRVAIEPACRVG 272 G V +L GDRVA+EP G Sbjct: 103 GEGVTHLRPGDRVAVEPGVPCG 124 Score = 79.8 bits (188), Expect = 5e-14 Identities = 38/87 (43%), Positives = 48/87 (55%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 GVPC C C GRY+LC D+ F P G + RY H A + KLPD++T EGALLE Sbjct: 120 GVPCGDCFLCLDGRYNLCEDVQFAGVYPYAGTIQRYKTHPAKWVHKLPDNLTYAEGALLE 179 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PL+V + G+ G +V G P Sbjct: 180 PLSVVMRGMSVAGLQLGRGAVVCGAGP 206 >UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Ochrobactrum anthropi ATCC 49188|Rep: Alcohol dehydrogenase GroES domain protein - Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168) Length = 358 Score = 80.6 bits (190), Expect = 3e-14 Identities = 39/100 (39%), Positives = 57/100 (57%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 L+ +DLR+ P+ EVL+ ++ GICGSD+HYW +G G + EP+I+GHEAS Sbjct: 12 LHAQDDLRIESRPVGTPGPGEVLIAVEAGGICGSDLHYWLEGGIGTIRVREPIILGHEAS 71 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTY 308 G + +G V L G VA+ P+ G S +Q T + Sbjct: 72 GRIKALGEGVTGLVPGQLVAMNPSQPCGICSFCQQGLTRH 111 Score = 51.6 bits (118), Expect = 2e-05 Identities = 35/97 (36%), Positives = 43/97 (44%), Gaps = 8/97 (8%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C FC+ G C M F + P G AAD CF +P+ + A Sbjct: 97 PCGICSFCQQGLTRHCSAMRFKGSAMYLPHQQGMFRDRIVIAADQCFPVPNGIDPGAAAC 156 Query: 431 LEPLAVGIHACKRG----GVSAGHVVLVLGRDPSASL 529 EPLAV +HA RG G G VV+V G P +L Sbjct: 157 SEPLAVCLHAANRGEAIAGSLVGKVVMVTGAGPIGAL 193 >UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative; n=16; Dikarya|Rep: Zinc-binding dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 349 Score = 79.8 bits (188), Expect = 5e-14 Identities = 34/85 (40%), Positives = 56/85 (65%), Gaps = 1/85 (1%) Frame = +3 Query: 3 ALLY-KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 ALLY +P + ++ + P+PEI +E+LL++D G+CG+D H + G F+ + P++ GH Sbjct: 8 ALLYSEPRNFKITKVPVPEIGPEEILLKVDICGVCGTDQHIHE----GEFIAKFPLVPGH 63 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIE 254 EA G + +G KVK +GDR+A + Sbjct: 64 EAVGRIVSMGDKVKGFDIGDRIAAD 88 Score = 44.4 bits (100), Expect = 0.003 Identities = 27/97 (27%), Positives = 42/97 (43%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G C YC +C+ G C + G Y K+ C+K+ + +T EE LLE Sbjct: 90 GETCGYCHYCRKGTDLFCENFAPAGVAR-DGGFADYIKYHFAKCYKIKN-LTDEEATLLE 147 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 P + IH + G VL++G P+ + +K Sbjct: 148 PASCAIHGMDVLKMPFGARVLLIGAGPTGLILAQLMK 184 >UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2; Saccharomycetaceae|Rep: Sorbitol dehydrogenase - Pichia stipitis (Yeast) Length = 381 Score = 79.8 bits (188), Expect = 5e-14 Identities = 35/77 (45%), Positives = 51/77 (66%), Gaps = 1/77 (1%) Frame = +3 Query: 45 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV-K 221 PIP +EVL+ + C GICGSD+H W+ G G+ L+ +I+GHE SG + IGS+V + Sbjct: 31 PIPICGRNEVLVHIKCTGICGSDIHVWKAGGIGNLQLKSDLILGHECSGEIIHIGSEVTE 90 Query: 222 NLTVGDRVAIEPACRVG 272 + +G++VAIEP G Sbjct: 91 DFEIGNKVAIEPQLPCG 107 Score = 66.1 bits (154), Expect = 7e-10 Identities = 36/94 (38%), Positives = 49/94 (52%), Gaps = 8/94 (8%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATP-------PVHGNLVRYYKHAADFCFKLPDHVTME 418 +PC C C G +LC ++ F P +HG++ RY F +KLPD+VT E Sbjct: 104 LPCGICFLCTNGNMNLCLNVDFMGMPGMPGRLPSIHGSIQRYKTLDPRFVYKLPDNVTYE 163 Query: 419 EGALLEPLAVGIHAC-KRGGVSAGHVVLVLGRDP 517 EGAL+E L+VG H K GG+ G + G P Sbjct: 164 EGALVEVLSVGYHGIQKAGGLELGKPCAIAGCGP 197 >UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4; Alphaproteobacteria|Rep: IdnD L-idonate 5-dehydrogenase - Rhizobium meliloti (Sinorhizobium meliloti) Length = 343 Score = 79.4 bits (187), Expect = 7e-14 Identities = 36/85 (42%), Positives = 54/85 (63%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ DLR+ + + + EV +R+ GICGSD+HY+ G G L+EPMI+GHE Sbjct: 5 VIHTAKDLRVEECAVEKPGPGEVEIRLAAGGICGSDLHYYNHGGFGTVRLKEPMILGHEV 64 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPA 260 SG VA +G V +L +GD VA+ P+ Sbjct: 65 SGHVAALGEGVSDLAIGDLVAVSPS 89 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 4/93 (4%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C++C G + C M F + P + G A C K + ++ E A+ Sbjct: 91 PCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQGAFRERLVAKASQCVKA-EGLSAGEAAM 149 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EPL+V +HA +R G G VLV G P +L Sbjct: 150 AEPLSVTLHATRRAGEMLGKRVLVTGCGPIGTL 182 >UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protein; n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol dehydrogenase GroES-like protein - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 347 Score = 79.4 bits (187), Expect = 7e-14 Identities = 36/85 (42%), Positives = 48/85 (56%), Gaps = 1/85 (1%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATP-PVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 GVPC CE C+ G Y+LC + F A P G Y H+A C+KLP++V EG L+ Sbjct: 93 GVPCGECEDCRKGHYNLCKHIKFMAIPHEKDGVFAEYCVHSASMCYKLPENVDTMEGGLM 152 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLG 508 EPL+V +HA + G +VLG Sbjct: 153 EPLSVALHATELSNAKIGETAIVLG 177 Score = 77.8 bits (183), Expect = 2e-13 Identities = 31/89 (34%), Positives = 56/89 (62%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 L V+ IP+ E+ +++ VG+CGSD+H++++G+ ++ L+ P+ +GHE G+V+ I Sbjct: 16 LEWVERDIPQPGRGELQIKLKHVGVCGSDLHFYKEGRLANWELDGPLALGHEPGGIVSAI 75 Query: 207 GSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 G V+ +GD+VA+EP G R+ Sbjct: 76 GEGVEGFEIGDKVALEPGVPCGECEDCRK 104 >UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 326 Score = 79.4 bits (187), Expect = 7e-14 Identities = 39/76 (51%), Positives = 53/76 (69%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 L + Q PIP+ +EDE+L++M+ GIC SDVH W G H+V + PMI GHE +G V + Sbjct: 22 LEIKQLPIPQPNEDELLVKMEYSGICHSDVHTWL-GDF-HYVSKCPMIGGHEGAGSVISV 79 Query: 207 GSKVKNLTVGDRVAIE 254 GSKVKN +GD+V I+ Sbjct: 80 GSKVKNWQIGDKVGIK 95 Score = 33.1 bits (72), Expect = 6.2 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 1/82 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGA-LLEPL 442 C CE+C+TG LCP ++ +G Y K+P + M A +L Sbjct: 101 CLNCEYCQTGHEPLCPH-VWNIGVQKYGTFQEYATIRDVDAIKIPKSMNMAAAAPVLCGG 159 Query: 443 AVGIHACKRGGVSAGHVVLVLG 508 A K V +G +V V G Sbjct: 160 VTAYKALKESEVKSGQIVAVTG 181 >UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 420 Score = 79.4 bits (187), Expect = 7e-14 Identities = 35/88 (39%), Positives = 53/88 (60%), Gaps = 4/88 (4%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 G+PC+ C+ C +GRY++C +M F ++ P G L H A +C LP +V++E G Sbjct: 103 GLPCKNCDLCASGRYNICKEMKFRSSAKAFPHFQGTLQERINHPAAYCHLLPSNVSLELG 162 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLG 508 A+LEPL+V IH +R + G VL+ G Sbjct: 163 AVLEPLSVAIHGSRRAALPKGKTVLIFG 190 Score = 77.8 bits (183), Expect = 2e-13 Identities = 34/84 (40%), Positives = 54/84 (64%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 ++L+ DL++ + EV + + G+CGSD+HY+ + G ++ EPM +GHE Sbjct: 18 SVLHGAKDLKVETRTLGVPEPTEVQVAVQATGLCGSDLHYYNHYRNGDIIVREPMTLGHE 77 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIE 254 ++GVV +GS+VKNL VGD VA+E Sbjct: 78 SAGVVTAVGSEVKNLKVGDHVALE 101 >UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein NCU07022.1; n=5; Pezizomycotina|Rep: Putative uncharacterized protein NCU07022.1 - Neurospora crassa Length = 437 Score = 79.0 bits (186), Expect = 1e-13 Identities = 39/88 (44%), Positives = 49/88 (55%), Gaps = 4/88 (4%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 GV C C C+ GRY+LC M F ++ P G L H A +C LPDH++ + Sbjct: 111 GVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQGTLQERINHPAIWCHILPDHISFDAA 170 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLG 508 ALLEPL+VGIHA R + G LVLG Sbjct: 171 ALLEPLSVGIHAVNRASPAPGSTALVLG 198 Score = 74.1 bits (174), Expect = 3e-12 Identities = 38/97 (39%), Positives = 56/97 (57%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 ++L+ P DLRL + I E E+ + + GICGSDV Y++K G P+ +GHE Sbjct: 26 SVLHGPRDLRLERRTIEEPELGELQVAVKTTGICGSDVSYYKKFANGDLCACMPLSLGHE 85 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 +SGVV IG +V ++GDRVA+E G + R+ Sbjct: 86 SSGVVVAIGPQVSGFSLGDRVALEVGVACGQCTICRK 122 >UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1; Filobasidiella neoformans|Rep: Xylitol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 375 Score = 77.8 bits (183), Expect = 2e-13 Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 3/85 (3%) Frame = +3 Query: 48 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVK-- 221 IPE DEV +++ G+CGSD+HY+ G G F + EP+++GHE+ GV+ +GS V Sbjct: 11 IPEPKADEVQIKVAMTGMCGSDLHYYLHGANGTFKIREPLVLGHESCGVITAVGSNVNSG 70 Query: 222 -NLTVGDRVAIEPACRVGTASSVRQ 293 NL VGDRVA+E T R+ Sbjct: 71 FNLKVGDRVAMEVGVYCKTCKMCRR 95 Score = 69.3 bits (162), Expect = 8e-11 Identities = 35/98 (35%), Positives = 55/98 (56%), Gaps = 4/98 (4%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 GV C+ C+ C+ GRY+LC +M F ++ P + G L A+ +KLP ++ + Sbjct: 84 GVYCKTCKMCRRGRYNLCANMRFASSAKTYPHLDGTLREVMTWPAELVYKLPPNLELPLA 143 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCS 538 AL EPL+V +HA +R +S G +LV+G L C+ Sbjct: 144 ALAEPLSVVLHAYRRAHLSPGSRILVIGAGAVGLLTCA 181 >UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Rep: Sorbitol dehydrogenase - Paracoccidioides brasiliensis Length = 124 Score = 77.4 bits (182), Expect = 3e-13 Identities = 36/86 (41%), Positives = 57/86 (66%), Gaps = 3/86 (3%) Frame = +3 Query: 6 LLYKPNDLRLVQ--TPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 +L+ P DLRL TP P+ E ++ +R G+CGSD+HY+ G+ G F+++ P+ +GH Sbjct: 14 VLHAPRDLRLESRLTPAPKHGELQIAIR--ATGLCGSDLHYYNHGRNGDFIVQSPLCLGH 71 Query: 180 EASGVVAKIGSKVKN-LTVGDRVAIE 254 E+SG++ IG V + +GDRVA+E Sbjct: 72 ESSGIITAIGPDVADTFHIGDRVALE 97 >UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Solibacter usitatus Ellin6076|Rep: Alcohol dehydrogenase GroES domain protein - Solibacter usitatus (strain Ellin6076) Length = 343 Score = 75.4 bits (177), Expect = 1e-12 Identities = 36/86 (41%), Positives = 50/86 (58%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A L R + PI + EV +R++ VGICGSD+H + +G G E PM++GHE Sbjct: 4 AELIAQRQFRFTEIPIEDPGPGEVQVRVNAVGICGSDLHSYAEGAIGDTPCEYPMVLGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPA 260 +G V K G+ V + GDR A+EPA Sbjct: 64 PAGTVVKTGTGVGGWSRGDRAALEPA 89 Score = 61.3 bits (142), Expect = 2e-08 Identities = 27/94 (28%), Positives = 47/94 (50%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C +CEFC++GR+++C ++ F + P G + +P +++E ++EPLA Sbjct: 92 CYHCEFCRSGRHNICANIRFLSNPGTPGFFREFVNLPVSNLLAIPPELSLELATIVEPLA 151 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 V +H+ K + V V G P L + LK Sbjct: 152 VALHSLKFAAIQPRETVAVFGAGPIGLLTIACLK 185 >UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1; Burkholderia phytofirmans PsJN|Rep: Alcohol dehydrogenase GroES-like - Burkholderia phytofirmans PsJN Length = 348 Score = 75.4 bits (177), Expect = 1e-12 Identities = 36/94 (38%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L++P +R+ + PE EV +R+ GICGSD+ Y+ KG+ G F + EP ++GHE Sbjct: 4 AVLHEPKLIRIDEVDPPEPGPGEVRVRVRAGGICGSDLSYYFKGKSGDFAVREPFVLGHE 63 Query: 183 ASGVVAKIGSKV---KNLTVGDRVAIEPACRVGT 275 +G + +G V + L G RVA+ P GT Sbjct: 64 VAGEIDSLGEGVTAERRLAPGQRVAVNPGLACGT 97 Score = 56.8 bits (131), Expect = 4e-07 Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 4/91 (4%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 G+ C C FC G + C +M F + P G +Y AA C +PD V + Sbjct: 92 GLACGTCRFCVGGMPNHCLNMRFMGSASTFPHTQGMFRQYIVVAARQCVPVPDGVDFAQA 151 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 ++ EPLAV +HA K+ G G VL++G P Sbjct: 152 SMAEPLAVALHAVKQAGSLVGASVLLVGCGP 182 >UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1; Filobasidiella neoformans|Rep: Xylitol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 469 Score = 75.4 bits (177), Expect = 1e-12 Identities = 34/87 (39%), Positives = 49/87 (56%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+PCR C CK G+ ++C +M +C P G+L RY+ AD +PDH++ EE ++ Sbjct: 134 GLPCRRCINCKEGKVNICLNMHYCGAPGSVGSLSRYFALPADMAPHIPDHLSWEEAGCIQ 193 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PLAVGI KR + V + G P Sbjct: 194 PLAVGIQVGKRVDLRPHKTVAIFGCGP 220 Score = 62.9 bits (146), Expect = 7e-09 Identities = 31/58 (53%), Positives = 38/58 (65%), Gaps = 2/58 (3%) Frame = +3 Query: 99 ICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPA--CR 266 ICGSD+H + G G + EP++MGHE+SG V +G VK VGDRVAIEP CR Sbjct: 81 ICGSDLHNYLAGGVGGRPVTEPIVMGHESSGEVIAVGDLVKTHKVGDRVAIEPGLPCR 138 >UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding domain protein; n=1; Kineococcus radiotolerans SRS30216|Rep: Alcohol dehydrogenase zinc-binding domain protein - Kineococcus radiotolerans SRS30216 Length = 347 Score = 74.1 bits (174), Expect = 3e-12 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 ++ P DLR+ + PE + EVL+R+ GICGSD+HY G+ G +V+ EP+++GHE Sbjct: 6 VHAPGDLRVEEVDAPEPAPGEVLVRIVYGGICGSDLHYAADGRNGAYVVTEPLVLGHEVV 65 Query: 189 GVVAKIGSKVKNL-TVGDRVAIEPA 260 GVV + G G RVA+ PA Sbjct: 66 GVVERAGPDTPAAPPAGTRVAVHPA 90 Score = 33.9 bits (74), Expect = 3.6 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Frame = +2 Query: 392 KLPDHVTMEEGALLEPLAVGIHACKR-GGVSAGHVVLVLGRDPSASLPCSQLK 547 +LP + + L EPLAV +HA R G AG VLV G P L + LK Sbjct: 139 ELPAALPLRRAVLAEPLAVALHAVGRLEGRVAGARVLVSGAGPIGVLAVAALK 191 >UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococcus oeni|Rep: Zc-binding dehydrogenase - Oenococcus oeni ATCC BAA-1163 Length = 385 Score = 73.7 bits (173), Expect = 4e-12 Identities = 40/101 (39%), Positives = 57/101 (56%), Gaps = 6/101 (5%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQ----CGHFVLEE--PM 167 +LY P D+RL + IP+ +D+V + + GICGSD+H + G H + E P+ Sbjct: 31 VLYGPKDMRLEKVDIPDPGKDQVQISVYFNGICGSDIHEYLDGMDLATVEHPITHEKAPL 90 Query: 168 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 I GHE +G V K G+ VK L VGD V +EP G ++ R Sbjct: 91 ISGHEFAGKVKKTGALVKGLKVGDHVTVEPIIACGYCAACR 131 Score = 48.8 bits (111), Expect = 1e-04 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPP------VHGNLVRYYKHAADFCFKLPDHVTMEE 421 + C YC C++G Y+LC + I +G L + + + KLPD + + Sbjct: 122 IACGYCAACRSGNYNLCENSIGEDNAAGFLGFSANGGLSQLCNVSYIYAHKLPDDLPLSL 181 Query: 422 GALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 GAL EP AV A + AG VL+ G P Sbjct: 182 GALCEPTAVAAQAIFNSKIHAGDDVLISGAGP 213 >UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7; Firmicutes|Rep: L-iditol 2-dehydrogenase - Lactobacillus plantarum Length = 352 Score = 73.3 bits (172), Expect = 5e-12 Identities = 36/78 (46%), Positives = 53/78 (67%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 +++ L Q PIPE++ D+VLL++ GICG+D+H + KGQ + V P+++GHE SG V Sbjct: 12 DNMELKQIPIPEVTGDKVLLKVAYTGICGTDIHTF-KGQYANAV--TPLVLGHEFSGEVV 68 Query: 201 KIGSKVKNLTVGDRVAIE 254 ++G VK L GDRV E Sbjct: 69 EVGPDVKTLKPGDRVTSE 86 Score = 45.2 bits (102), Expect = 0.001 Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = +2 Query: 275 CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGI 454 C +C+ Y+LCP+ + T +G++ Y + LPD+V+ + A+ EPLA + Sbjct: 95 CVYCQDKEYNLCPNRVGIGTK-ANGSMANYVLTREESAHILPDNVSYKMAAMSEPLASCV 153 Query: 455 HAC-KRGGVSAGHVVLVLGRDPSASL 529 HA ++ + +L++G P L Sbjct: 154 HAMYQKTPFTLHDTLLIMGPGPMGLL 179 >UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein NCU01905.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU01905.1 - Neurospora crassa Length = 412 Score = 73.3 bits (172), Expect = 5e-12 Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 4/88 (4%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 ++L+ DL + P+P +S +VL+ + G+CGSD+HY+ + G + EP+ +GHE Sbjct: 8 SVLHGARDLSVESRPLPTLSPTDVLISIKSTGLCGSDLHYYTHFRNGDIQVHEPLTLGHE 67 Query: 183 ASGVVAKIG----SKVKNLTVGDRVAIE 254 +SG++ IG S L VGDRVA+E Sbjct: 68 SSGIITAIGSPSVSSEYGLNVGDRVALE 95 Score = 50.4 bits (115), Expect(2) = 2e-05 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Frame = +2 Query: 290 TGRYHLCPDMIFCAT-------PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAV 448 T RY++C M F ++ P G L H A +C KLP+ V GAL EPLAV Sbjct: 136 TSRYNICRAMRFRSSAKGWPQFPHAQGTLQEVVAHPAKWCHKLPESVDYTLGALAEPLAV 195 Query: 449 GIHACKRGGV 478 +HA R G+ Sbjct: 196 AMHAAGRAGI 205 Score = 20.6 bits (41), Expect(2) = 2e-05 Identities = 6/10 (60%), Positives = 6/10 (60%) Frame = +2 Query: 257 GVPCRYCEFC 286 G PC CE C Sbjct: 97 GQPCEACELC 106 >UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Thermofilum pendens Hrk 5|Rep: Alcohol dehydrogenase GroES domain protein - Thermofilum pendens (strain Hrk 5) Length = 398 Score = 73.3 bits (172), Expect = 5e-12 Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 4/94 (4%) Frame = +3 Query: 45 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF----VLEEPMIMGHEASGVVAKIGS 212 P+PE DE+L+R+ VGICGSD+H+ + G+ + P+++GHE SGVV K+G+ Sbjct: 47 PVPEPKPDEILIRVKAVGICGSDIHFLETDSEGYILYPGLTRFPVVIGHEFSGVVEKVGT 106 Query: 213 KVKNLTVGDRVAIEPACRVGTASSVRQDDTTYAL 314 VK GD V E G + R D + L Sbjct: 107 NVKTFKPGDMVTSEEMFWCGECDACRSVDFNHCL 140 >UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related Zn-dependent dehydrogenases; n=1; Pelotomaculum thermopropionicum SI|Rep: Threonine dehydrogenase and related Zn-dependent dehydrogenases - Pelotomaculum thermopropionicum SI Length = 329 Score = 72.9 bits (171), Expect = 6e-12 Identities = 37/95 (38%), Positives = 54/95 (56%) Frame = +3 Query: 12 YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 191 Y D+R+ P P DEVL+++ GICGSD+H ++KG F+ P+ MGHE SG Sbjct: 7 YGIGDIRVENIPKPAPGHDEVLVKVAYAGICGSDLHIFRKGM---FISSAPVTMGHEFSG 63 Query: 192 VVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQD 296 VV ++G+ V L GD+V +P G R++ Sbjct: 64 VVEEVGAGVTGLRPGDQVVGDPRVPCGRCQWCRRE 98 Score = 53.2 bits (122), Expect = 5e-06 Identities = 30/98 (30%), Positives = 49/98 (50%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 VPC C++C+ +Y+LCP + F G + K+P + ++E L+EP Sbjct: 87 VPCGRCQWCRREQYNLCPGLGFIGEVRP-GCFAEHIAINYKKLLKVPA-LDLKEAVLVEP 144 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 LAV +H K+G +S + V +LG P L + K + Sbjct: 145 LAVAVHIAKKGKLSPENTVGILGAGPIGLLTLAAAKAI 182 >UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2; Bacteria|Rep: L-threonine 3-dehydrogenase - Prochlorococcus marinus str. MIT 9211 Length = 379 Score = 72.9 bits (171), Expect = 6e-12 Identities = 32/76 (42%), Positives = 46/76 (60%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 L +VQ P+PEI DEVL+++ GICG+D+H W + PMI GHE +G + +I Sbjct: 50 LWMVQAPVPEIGPDEVLIKVRKTGICGTDIHIWNWDDWASATVPTPMITGHEFAGEIVEI 109 Query: 207 GSKVKNLTVGDRVAIE 254 G V L++G R + E Sbjct: 110 GRDVTGLSIGQRCSGE 125 >UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2; Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus iheyensis Length = 342 Score = 72.5 bits (170), Expect = 8e-12 Identities = 34/90 (37%), Positives = 54/90 (60%) Frame = +3 Query: 48 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNL 227 +PE+ +EV ++++ GICGSD+H + KG H + P+++GHE +G V ++GS V Sbjct: 19 VPELKPNEVQIKVNVAGICGSDIHTY-KGL--HPFRKPPVVIGHEVAGEVVEVGSSVTKF 75 Query: 228 TVGDRVAIEPACRVGTASSVRQDDTTYALT 317 VGDRV +EP G + V + Y+ T Sbjct: 76 KVGDRVTVEPQIGTGESEGVMTGNVNYSDT 105 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/67 (37%), Positives = 36/67 (53%) Frame = +2 Query: 347 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSAS 526 G + Y+ + KLPD V+ ++G L+EPLAVG+HA +G V V +LG P Sbjct: 116 GTMAEYFASPEEQVIKLPDSVSYDQGVLVEPLAVGVHAAFKGDVQPTDRVAILGAGPIGL 175 Query: 527 LPCSQLK 547 L +K Sbjct: 176 LTLIAVK 182 >UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC 14580|Rep: YjmD - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 338 Score = 71.7 bits (168), Expect = 1e-11 Identities = 36/100 (36%), Positives = 54/100 (54%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A++ KP + P PE + EVL+++ GICGSDVH++ + P I GHE Sbjct: 4 AVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNP---YAQYPQIFGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDT 302 +G++ K G+ V+ + G+RV IEPA G R+ T Sbjct: 61 LAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRT 100 Score = 44.4 bits (100), Expect = 0.003 Identities = 22/96 (22%), Positives = 41/96 (42%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC C C+ GR + C ++ + G + +P+ + AL EP Sbjct: 87 IPCGGCYPCRKGRTNACMNIDMIGSVR-RGGFADFIIVPETHVHPIPEQMDFATAALCEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 ++G A +R + G +++LG P +Q+K Sbjct: 146 FSIGAQAVRRADIQTGETIVILGMGPIGLTILAQVK 181 >UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Rep: CG4836-PC, isoform C - Drosophila melanogaster (Fruit fly) Length = 1217 Score = 71.7 bits (168), Expect = 1e-11 Identities = 33/90 (36%), Positives = 52/90 (57%) Frame = +2 Query: 254 AGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 + + C C+ CK G Y++C +++ +G L Y H AD C +LP+ ++ME GAL Sbjct: 959 SALSCGICDLCKKGLYNMCSGLVY------NGFLSTYQTHPADLCHRLPESISMEAGALT 1012 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDPSA 523 + LA+G AC + V+ VL+LG P+A Sbjct: 1013 QTLALGCQACFKANVTPTSNVLILGACPTA 1042 Score = 55.6 bits (128), Expect = 1e-06 Identities = 29/85 (34%), Positives = 48/85 (56%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 P ++ +V P + +VL+R V + SD+H ++ G E M +GH+A+G+V Sbjct: 884 PYEISVVPFSKPRPKDFDVLIRTGSVAVSNSDIHVYENGNRDM----EAMSLGHDATGIV 939 Query: 198 AKIGSKVKNLTVGDRVAIEPACRVG 272 ++G V++L VGDRV +E A G Sbjct: 940 EELGRCVQHLHVGDRVVMESALSCG 964 >UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol dehydrogenase; n=3; Actinomycetales|Rep: Putative zinc-binding alcohol dehydrogenase - Streptomyces coelicolor Length = 358 Score = 71.3 bits (167), Expect = 2e-11 Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +++ DLR+ P+ E L+ + G+CGSD+HYW+ G G F L EPM++GHE Sbjct: 16 VIHGAGDLRVTDVPVRPPGPGEALVAVRYGGVCGSDLHYWRHGGVGDFHLREPMLLGHEV 75 Query: 186 SGVVAKIGS-KVKNLTVGDRVAIEPACRVG 272 G V GS G VA+ PA G Sbjct: 76 VGTVVAYGSPDTPGPAAGTSVAVHPATPCG 105 Score = 47.6 bits (108), Expect = 3e-04 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 4/99 (4%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C C R ++C D + + P V G A LP + AL Sbjct: 103 PCGVCPECVDRRRNVCRDTRYLGSAARFPHVQGGFAARIVVPAGQLRPLPAGLDPRRAAL 162 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 EPL+V +HA +R G AG VLV G P L + K Sbjct: 163 AEPLSVALHAVRRAGDPAGRHVLVTGAGPIGCLVVAAAK 201 Score = 33.1 bits (72), Expect = 6.2 Identities = 17/40 (42%), Positives = 27/40 (67%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEA 660 AKA GA V + D+L + L++A++ GAD TL+ D ++A Sbjct: 200 AKAAGAAHVTVTDLLPAALEYARAAGAD-TLVRADDPDDA 238 >UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to sorbitol dehydrogenase - Candidatus Kuenenia stuttgartiensis Length = 339 Score = 70.9 bits (166), Expect = 3e-11 Identities = 32/83 (38%), Positives = 50/83 (60%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ Y ND+R+ + P P+I E+L+++ GICGSDV W + + + P+++GHE Sbjct: 4 AMYYNNNDVRIEEMPTPQIGPGELLVKIFASGICGSDVMEWYR------IKKAPLVLGHE 57 Query: 183 ASGVVAKIGSKVKNLTVGDRVAI 251 +G + IG VK VGDRV + Sbjct: 58 IAGEIVAIGDAVKQFKVGDRVTV 80 Score = 41.1 bits (92), Expect = 0.024 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCAT-PPVHGNLVRYYKHAADF-CFKLPDHVTMEEGALL 433 VPC C +C G + +C + P +R + D F LP ++ +EG + Sbjct: 84 VPCNTCHYCLNGHHSVCDTLRTTNFYPGGFAEFLRVPQINVDRGTFILPQEMSYDEGTFV 143 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EPLA I + G +LV+G S L Sbjct: 144 EPLACSIRGQRLSNFKPGQSLLVIGSGISGLL 175 Score = 33.9 bits (74), Expect = 3.6 Identities = 16/36 (44%), Positives = 22/36 (61%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKD 648 A+A GA K+ DI + RL FAK +GAD + +D Sbjct: 180 ARALGAGKIFATDINEYRLKFAKKIGADIAINAKED 215 >UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Nocardioides sp. JS614|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 338 Score = 70.9 bits (166), Expect = 3e-11 Identities = 36/86 (41%), Positives = 45/86 (52%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC CE C+ G +LCPD+ F + G L F LPD ++ + GALLEP Sbjct: 86 IPCGVCEQCRAGHGNLCPDVRFAGHAGLDGGLQERLVWPDHLLFPLPDDLSDDAGALLEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 L V IHA V GH VLV+G P Sbjct: 146 LGVAIHAVGVAHVRPGHDVLVVGGGP 171 Score = 51.2 bits (117), Expect = 2e-05 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 3/99 (3%) Frame = +3 Query: 3 ALLYKPNDLRLVQT---PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 173 A L+ DLR+ Q P P + V + VG+CGSD+H++ G G L+ P++ Sbjct: 5 ARLHSVGDLRVEQVAEPPAPTVGWSTVAVTS--VGLCGSDLHWFTDGGTGEVTLDRPVVP 62 Query: 174 GHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 GHE + G + G RVAI+PA G R Sbjct: 63 GHELA------GRALDGPYAGRRVAIDPAIPCGVCEQCR 95 >UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase; n=1; Rhodobacter sphaeroides 2.4.1|Rep: Zinc-containing alcohol dehydrogenase - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 337 Score = 70.5 bits (165), Expect = 3e-11 Identities = 35/88 (39%), Positives = 50/88 (56%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 LRL PI E DEVL+R+D ICG+D H + G F + P+++GHE +G V ++ Sbjct: 12 LRLTDLPIQEPGPDEVLIRIDSATICGTDQHILE----GKFWAKPPVVLGHEFAGYVERV 67 Query: 207 GSKVKNLTVGDRVAIEPACRVGTASSVR 290 G +V+N GD V++EP G R Sbjct: 68 GERVQNCRPGDLVSVEPHVYCGCCKPCR 95 >UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain protein; n=3; Bacteria|Rep: Alcohol dehydrogenase GroES domain protein - Solibacter usitatus (strain Ellin6076) Length = 343 Score = 70.5 bits (165), Expect = 3e-11 Identities = 37/89 (41%), Positives = 53/89 (59%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 LL + L +V+ P+P I D+VL+R+ GICGSDVH G+ G + P++MGHEA Sbjct: 5 LLTQYMHLEMVEMPVPAIGADDVLVRVRACGICGSDVH-GLDGKTGRRI--PPLVMGHEA 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 +G V + G+ V +L GDRV + G Sbjct: 62 AGEVVETGANVTDLRPGDRVTFDSTVYCG 90 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 4/87 (4%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPV----HGNLVRYYKHAADFCFKLPDHVTMEEGA 427 V C C C G +LC + P HG Y ++LPD ++ E+ A Sbjct: 87 VYCGRCFHCTRGEVNLCDNREVLGVSPGPYRRHGAFAEYVSVPRRIMYRLPDSLSYEQAA 146 Query: 428 LLEPLAVGIHACKRGGVSAGHVVLVLG 508 L+E ++V +HA V G +V+G Sbjct: 147 LIEAVSVAVHAVNLTPVRLGDSAVVVG 173 >UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=5; Actinobacteria (class)|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Arthrobacter sp. (strain FB24) Length = 355 Score = 70.1 bits (164), Expect = 4e-11 Identities = 31/79 (39%), Positives = 42/79 (53%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 DLR+ P+P DE ++ + GICGSD+HYW G G +L PM++GHE G V Sbjct: 21 DLRIEDVPVPPPGPDEAVVEVAFGGICGSDLHYWLHGAAGESILRVPMVLGHEIVGTVLH 80 Query: 204 IGSKVKNLTVGDRVAIEPA 260 + G VA+ PA Sbjct: 81 AAADGTGPEAGTPVAVHPA 99 Score = 43.2 bits (97), Expect = 0.006 Identities = 25/71 (35%), Positives = 32/71 (45%) Frame = +2 Query: 335 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRD 514 P G RY A LPD +++ AL EP +V HA R G G LV+G Sbjct: 129 PHTDGAFSRYATLPARMLRPLPDGLSLRTAALAEPASVAWHAVARAGDVTGKTALVIGSG 188 Query: 515 PSASLPCSQLK 547 P +L + LK Sbjct: 189 PIGALAVAVLK 199 >UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2; Clostridiales|Rep: Putative uncharacterized protein - Dorea longicatena DSM 13814 Length = 347 Score = 69.3 bits (162), Expect = 8e-11 Identities = 33/89 (37%), Positives = 52/89 (58%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 ++ KP ++ + P+PE+ +D+VL+++ +GICGSD+H + G+ H P+ GHE Sbjct: 11 VMTKPGEIIFREVPVPEVKDDQVLVKIMNIGICGSDIHVYH-GK--HPFTSYPVTQGHEV 67 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 SG V K+G V G +V IEP G Sbjct: 68 SGEVVKLGKDVTVFHEGQKVTIEPQVYCG 96 Score = 58.0 bits (134), Expect = 2e-07 Identities = 32/102 (31%), Positives = 49/102 (48%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C C C+ G+Y+LC ++ G Y+ A +P+ ++ EEGA++EP Sbjct: 93 VYCGECYPCRHGKYNLCEELKVMGFQTT-GTASEYFAVDASKVTPIPEEMSYEEGAMIEP 151 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 LAV +H K+ G G + VLG P +L K + K Sbjct: 152 LAVAVHGVKQVGDVKGMNIAVLGAGPIGNLVAQAAKGMGAAK 193 >UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily, zinc-containing; n=1; Moorella thermoacetica ATCC 39073|Rep: Alcohol dehydrogenase superfamily, zinc-containing - Moorella thermoacetica (strain ATCC 39073) Length = 358 Score = 68.5 bits (160), Expect = 1e-10 Identities = 36/83 (43%), Positives = 48/83 (57%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ PND+RLV+ P+P+ EVL+R+ GICG+DV KG E GHE Sbjct: 13 VLFGPNDVRLVEKPVPKPGPGEVLVRVAACGICGTDVKIITKGMPKMPPYGE-FTFGHEW 71 Query: 186 SGVVAKIGSKVKNLTVGDRVAIE 254 +G + +G V VGDRVAIE Sbjct: 72 AGTIVALGETVDEFQVGDRVAIE 94 Score = 41.9 bits (94), Expect = 0.013 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 7/91 (7%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDM------IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGA 427 C CE C G+Y C + A V G Y + +K+PD++T E Sbjct: 99 CGRCENCIDGKYTACLNYGRLDKGHRAAGMTVDGGFAEYAVQHVNSVYKIPDNITFNEAT 158 Query: 428 LLEPLAVGIHAC-KRGGVSAGHVVLVLGRDP 517 + ++A K GG AG VLV+G P Sbjct: 159 YVTTAGCALYAIDKSGGYIAGDTVLVIGPGP 189 >UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase; n=1; uncultured bacterium|Rep: 6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase - uncultured bacterium Length = 340 Score = 68.5 bits (160), Expect = 1e-10 Identities = 32/93 (34%), Positives = 53/93 (56%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 K L++ P+P+I D++L+++ G+C +D+HY + G + P+++GHEASG+ Sbjct: 9 KDAGLKIEDIPVPQIKGDQILVKVAACGVCHTDLHYIEHGV--PTFKKPPIVLGHEASGI 66 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 V K G+ V N+ G RV I G + RQ Sbjct: 67 VEKAGANVTNVKPGQRVLIPAVLTCGHCPACRQ 99 >UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Rhodobacter sphaeroides ATCC 17029|Rep: Alcohol dehydrogenase GroES domain protein - Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) Length = 345 Score = 68.5 bits (160), Expect = 1e-10 Identities = 34/84 (40%), Positives = 50/84 (59%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 DL + P + EV L + GICGSD+HY+Q G+ + +L EPMI+GHE SG + + Sbjct: 11 DLSIEPWAEPALQAGEVRLDLAWGGICGSDLHYFQHGRVANSILREPMILGHEFSGRIRE 70 Query: 204 IGSKVKNLTVGDRVAIEPACRVGT 275 +G V+ L G VA+ P+ G+ Sbjct: 71 VGPGVQWLKPGMAVAVNPSRPCGS 94 Score = 58.0 bits (134), Expect = 2e-07 Identities = 34/93 (36%), Positives = 42/93 (45%), Gaps = 4/93 (4%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC C+ C G HLC M F + P HG A C LP+ V + AL Sbjct: 91 PCGSCDQCSAGLTHLCRSMRFMGSAAHFPHTHGGFAERPVVLASQCVALPETVDLALAAL 150 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EP AV +HA + ++AG VLV G SL Sbjct: 151 SEPYAVALHAVELAQIAAGASVLVTGAGTIGSL 183 >UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus iheyensis Length = 351 Score = 68.1 bits (159), Expect = 2e-10 Identities = 41/98 (41%), Positives = 57/98 (58%), Gaps = 8/98 (8%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG----QCG--HFVLEE- 161 A+ Y +D+R+ P I +V +++ GICGSD+H + Q G H V E Sbjct: 4 AVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEM 63 Query: 162 -PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 P+ +GHE SGV+ +IG V L+VGDRVAIEPA + G Sbjct: 64 APLTLGHEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCG 101 Score = 56.0 bits (129), Expect = 8e-07 Identities = 48/151 (31%), Positives = 57/151 (37%), Gaps = 4/151 (2%) Frame = +2 Query: 77 AAHGLRGYLRVRRPLLAEGSMRTLRAGRTNDHGTRSFRSSGQDRFESQESDSW*SSGHRA 256 A HG G ++V P G M L G SG E E S S G R Sbjct: 43 AYHGAEGVVQVGEPHPVTGEMAPLTLGH---------EFSGVIH-EIGEGVSGLSVGDRV 92 Query: 257 GVP----CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEG 424 + C CE C G Y+LC F G Y KLPD+++ EE Sbjct: 93 AIEPAIKCGKCENCVRGNYNLCEHNGFVGLQS-DGAFAEYAIVDPHMVHKLPDNISFEEA 151 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 +EP AV HA K + AG V V G P Sbjct: 152 TAIEPTAVSFHALKLSNMKAGDTVAVFGVGP 182 Score = 32.7 bits (71), Expect = 8.2 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AKA GA ++ ID+ RL+ A+ LGA T++ + N AE + Sbjct: 191 AKAAGASRIYAIDVSNERLEMAQKLGAT-TVINAIEENAAEKI 232 >UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol dehydrogenase; n=1; Pelobacter carbinolicus DSM 2380|Rep: Putative zinc-containing alcohol dehydrogenase - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 327 Score = 68.1 bits (159), Expect = 2e-10 Identities = 34/85 (40%), Positives = 49/85 (57%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A L +P + + +TPIP EVL+R G+CGSD + G F + P+I GHE Sbjct: 4 AQLVEPGKITIQETPIPSPKPGEVLIRTSVAGLCGSDHSVYH----GKFDVPLPVIPGHE 59 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 A G + ++G V N++VG RV I+P Sbjct: 60 AIGTIVELGEGVTNVSVGQRVTIQP 84 Score = 42.3 bits (95), Expect = 0.010 Identities = 24/81 (29%), Positives = 35/81 (43%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C CK+G ++CP I +G L Y + + + LP + E EPLA Sbjct: 88 CGVCPLCKSGHDNICPSKIRLGID-TNGVLAEYVTAPSRYVWALPADLPDEVAVFTEPLA 146 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 V +H + VLV+G Sbjct: 147 VAVHGVNMLPPNKDDRVLVMG 167 >UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to zinc-containing dehydrogenase - Candidatus Kuenenia stuttgartiensis Length = 386 Score = 68.1 bits (159), Expect = 2e-10 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 4/85 (4%) Frame = +3 Query: 48 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVL----EEPMIMGHEASGVVAKIGSK 215 +P + +DE+L+R+ GICGSD H ++ + G+ + E P I+GHE SG+V + G Sbjct: 47 VPNLQDDEILVRIKSCGICGSDTHLYETDKDGYIIFSGVTELPRIIGHELSGIVEQTGKN 106 Query: 216 VKNLTVGDRVAIEPACRVGTASSVR 290 V+N++ GD +A E G + R Sbjct: 107 VRNVSKGDWIAAESIMWCGMCHACR 131 >UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36; Proteobacteria|Rep: Starvation-sensing protein rspB - Escherichia coli (strain K12) Length = 339 Score = 68.1 bits (159), Expect = 2e-10 Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHE 182 L+ KPN L +V+ IP S EV +++ GICGSD H ++ GH + P ++GHE Sbjct: 5 LIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIYR----GHNPFAKYPRVIGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 GV+ +G V++ VG+RVA++P G Sbjct: 61 FFGVIDAVGEGVESARVGERVAVDPVVSCG 90 Score = 36.7 bits (81), Expect = 0.51 Identities = 23/102 (22%), Positives = 39/102 (38%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C +C C G+ ++C + G Y A +K+P+ V + ++EP Sbjct: 87 VSCGHCYPCSIGKPNVCTTLAVLGVH-ADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 + + G + VLV G P LK + + K Sbjct: 146 FTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQVLKGVYNVK 187 >UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7; Clostridium|Rep: Sorbitol dehydrogenase - Clostridium botulinum A str. ATCC 3502 Length = 349 Score = 67.7 bits (158), Expect = 2e-10 Identities = 36/88 (40%), Positives = 51/88 (57%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 L+ DLR + IP I E++VL+R+ VGICGSD+ H+ P I GHE S Sbjct: 10 LHAIKDLRYEEVDIPTIGENDVLVRVKYVGICGSDMPRAMVSGAYHY----PTITGHEFS 65 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVG 272 G V +IG+ V ++ VG+R+A+ P G Sbjct: 66 GEVVEIGNNVDDIKVGERIAVAPLIPCG 93 Score = 52.8 bits (121), Expect = 7e-06 Identities = 26/86 (30%), Positives = 39/86 (45%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC CEFCK G + LC F + G Y + + LP+ + E A +EP Sbjct: 90 IPCGECEFCKKGNFALCETYEFLGSRN-DGGFAEYVRVPKENVLILPEDLDYETAAGIEP 148 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 ++ A + G+ G V V+G P Sbjct: 149 ASISYQAMSKTGIKVGDTVAVVGCGP 174 Score = 41.9 bits (94), Expect = 0.013 Identities = 20/43 (46%), Positives = 29/43 (67%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELV 669 AK FGA KV+ +D+L+ +L+ AK LGAD ++ K+ N E V Sbjct: 183 AKIFGASKVIAVDVLEDKLNLAKELGAD-IIINSKECNAVEKV 224 >UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogenase family protein; n=3; Bacteria|Rep: Oxidoreductase, zinc-binding dehydrogenase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 363 Score = 67.7 bits (158), Expect = 2e-10 Identities = 32/85 (37%), Positives = 52/85 (61%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A++Y P D+R+ Q P+P EVLL++ G+CGSD+ + G +V+ P+I GHE Sbjct: 24 AVMYAPGDIRVEQAPVPRPGPGEVLLKVAACGVCGSDIPRMLRN--GGYVM--PIICGHE 79 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 SG V ++G V+ +G+ V++ P Sbjct: 80 FSGWVVELGDGVEGFDIGELVSVPP 104 Score = 59.7 bits (138), Expect = 6e-08 Identities = 28/86 (32%), Positives = 43/86 (50%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PCR C+FC G + LC + + + G +Y KLP + A+L+P Sbjct: 106 IPCRRCDFCAKGEFGLCENYDYFGSRS-DGAYAQYVVSPVGNLLKLPAGIDPRAAAMLDP 164 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 A+ +H + G+ AGH VLV+G P Sbjct: 165 AAIALHGLWKTGLRAGHRVLVIGAGP 190 >UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28; Bacillales|Rep: Sorbitol dehydrogenase - Bacillus halodurans Length = 354 Score = 67.3 bits (157), Expect = 3e-10 Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 LY DLR +TP P I +D++++++ VGICGSD+ ++K G +V M GHE Sbjct: 6 LYGIQDLRFEETPAPSIEHDDDIIIKVKAVGICGSDLSRYKK--LGPYV--PGMTFGHEF 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 +G V KIG V ++GDRVA P G Sbjct: 62 AGEVVKIGRSVTGFSIGDRVAACPTYTCG 90 Score = 41.9 bits (94), Expect = 0.013 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 C C +C+ G C + + A P G Y K A LP+ V +E AL+EP Sbjct: 89 CGQCRYCQLGEPTRCERLSVIGARHP--GAYAEYVKLPAKHVIPLPNVVNYDEAALIEPA 146 Query: 443 AVGIHACKRGGVSAGHVVLVLG 508 +V H R + G V ++G Sbjct: 147 SVVAHGFYRTNIKPGASVAIMG 168 >UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=1; Ralstonia eutropha JMP134|Rep: Zinc-containing alcohol dehydrogenase superfamily - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 367 Score = 67.3 bits (157), Expect = 3e-10 Identities = 45/121 (37%), Positives = 63/121 (52%), Gaps = 10/121 (8%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L P +L+ + PIPEI +D+ +LR++ G+CG+D W G + P+I GHE Sbjct: 9 VLESPKNLQAREFPIPEIGDDDAVLRVEACGLCGTDYEQW-LGHMKDWGGGMPIIPGHEI 67 Query: 186 SGVVAKIG---SKVKNLTVGDRVAIEPACRVGTASS-VR------QDDTTYALT*SSAPR 335 G + +IG +K N+ GDRVAIEP G VR Q D Y L S+A Sbjct: 68 MGFIERIGTLAAKRWNVREGDRVAIEPIIPCGHCEDCVRGAYTRCQSDLGYGLYQSTAVA 127 Query: 336 P 338 P Sbjct: 128 P 128 Score = 36.7 bits (81), Expect = 0.51 Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 9/92 (9%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCP-DMIF------CATPPVHGNLVRY-YKHAADFCFKLPDHVTM 415 +PC +CE C G Y C D+ + P + G + Y H KLP + Sbjct: 96 IPCGHCEDCVRGAYTRCQSDLGYGLYQSTAVAPHLWGGYATHVYLHPRTMVHKLPTDLPT 155 Query: 416 EEGALLEPLAVGIH-ACKRGGVSAGHVVLVLG 508 E L+ PL+ I + GG G V++ G Sbjct: 156 EVMTLVNPLSNAIRWVYEAGGAGLGKTVVIAG 187 >UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep: Lin2813 protein - Listeria innocua Length = 350 Score = 66.9 bits (156), Expect = 4e-10 Identities = 34/82 (41%), Positives = 50/82 (60%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+LY+ N ++ Q +D+V + + VGICGSD+H Q + P +MGHE Sbjct: 4 AVLYENNVIKAEQIDEATCGKDQVRVEVKAVGICGSDIHKMQT----RWKYPLPAVMGHE 59 Query: 183 ASGVVAKIGSKVKNLTVGDRVA 248 +GVV +IGS+V N+ +GDRVA Sbjct: 60 FAGVVTEIGSEVTNVAIGDRVA 81 Score = 48.0 bits (109), Expect = 2e-04 Identities = 27/82 (32%), Positives = 37/82 (45%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 PC C +CK G + LC + + HG AD + D + EEGA++EPL Sbjct: 87 PCMECNYCKAGDFALCDNYRMVGSH-FHGGFAENVVMKADNVISIGD-LDFEEGAMIEPL 144 Query: 443 AVGIHACKRGGVSAGHVVLVLG 508 AV +H G V+V G Sbjct: 145 AVSMHGVLGIEPRLGDTVIVFG 166 >UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2; Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 364 Score = 66.9 bits (156), Expect = 4e-10 Identities = 33/92 (35%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC---------GHFVLEE 161 L+ D+RL PIP+ D+V +R+ GICGSD+H +Q G H + Sbjct: 6 LHGRQDIRLDTVPIPDCLSDQVRVRVAYCGICGSDIHEYQAGPILAPQPQETNPHSGAKL 65 Query: 162 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEP 257 P+I+GHE SG V ++G+ V+ + +G +V + P Sbjct: 66 PVILGHEISGTVVEVGADVEGIRIGQKVVVNP 97 Score = 49.6 bits (113), Expect = 7e-05 Identities = 26/81 (32%), Positives = 37/81 (45%) Frame = +2 Query: 275 CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGI 454 C C GR++ C + G A +PD+V++ AL EPLAV Sbjct: 109 CTSCLRGRFNTCKRATYYGINAPGGGFSGEISVNAANIVPVPDNVSLRAAALAEPLAVAC 168 Query: 455 HACKRGGVSAGHVVLVLGRDP 517 H +R G +AG +L+LG P Sbjct: 169 HMIERSGFAAGDNILILGAGP 189 >UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1; Haloarcula marismortui|Rep: Zinc-binding dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 344 Score = 66.9 bits (156), Expect = 4e-10 Identities = 30/84 (35%), Positives = 49/84 (58%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 230 P+ ++DEVL+++ +C +D H + G F E P+++GHE +G VA++G+ V Sbjct: 20 PDPADDEVLVQVGACSVCMTDYHMYH----GTFAAETPLVLGHEGAGTVAEVGADVDRFA 75 Query: 231 VGDRVAIEPACRVGTASSVRQDDT 302 VGDRVAI P S ++ +T Sbjct: 76 VGDRVAINPTVPCNACSYCKKGET 99 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPD--MIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 VPC C +CK G HLC + I A + Y + ++ E AL Sbjct: 86 VPCNACSYCKKGETHLCENNTSIGGAGDTILDGAFAEYVRVPAINVEDIGEMSFERAALA 145 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EPLA +H ++ + G V ++G P Sbjct: 146 EPLACCVHGVEQADIKPGDSVGIIGAGP 173 >UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1; Clostridium cellulolyticum H10|Rep: Alcohol dehydrogenase GroES-like - Clostridium cellulolyticum H10 Length = 356 Score = 66.5 bits (155), Expect = 5e-10 Identities = 35/85 (41%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDV-HYWQKGQCGHFVLEEPMIMGHE 182 L+ P D+R IP IS D +V+++++ G+CGSD+ KG + P+++GHE Sbjct: 10 LFAPGDVRCELIDIPVISADNQVIIKVEACGVCGSDIPRVMSKGAYRY-----PIVIGHE 64 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 SG V ++G+KVKN VGDRV P Sbjct: 65 FSGEVVEVGTKVKNAKVGDRVTAMP 89 Score = 52.8 bits (121), Expect = 7e-06 Identities = 22/83 (26%), Positives = 45/83 (54%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C+ C++CK G+ C + + + + G + Y + + +PD+V+ E A+ +P Sbjct: 91 VNCKECDYCKIGQAITCDNYDYYGSR-IDGAMAEYIVVSEENIIHIPDNVSYYEAAMTDP 149 Query: 440 LAVGIHACKRGGVSAGHVVLVLG 508 ++V +HA ++ + AG +V G Sbjct: 150 VSVALHAVRKAEIEAGQTAVVFG 172 Score = 37.5 bits (83), Expect = 0.29 Identities = 15/27 (55%), Positives = 19/27 (70%) Frame = +1 Query: 544 KAFGAHKVLIIDILQSRLDFAKSLGAD 624 K G HKV+ +DI+ +LD AK LGAD Sbjct: 185 KHMGCHKVIAVDIIDEKLDMAKKLGAD 211 >UniRef50_Q5K7P7 Cluster: (R,R)-butanediol dehydrogenase, putative; n=2; Dikarya|Rep: (R,R)-butanediol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 441 Score = 66.5 bits (155), Expect = 5e-10 Identities = 31/91 (34%), Positives = 55/91 (60%), Gaps = 1/91 (1%) Frame = +3 Query: 24 DLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 D+R+V PIP+I++D +V++++ ICGSD+H + G +++ I+GHE G++ Sbjct: 42 DVRMVDAPIPDITQDTDVIVKVTGTTICGSDLHLYHSEMLG---MQKGDILGHEFMGIID 98 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 ++G V +L +GDRV + GT +Q Sbjct: 99 RVGPSVNHLKIGDRVVVSFQIACGTCRYCQQ 129 >UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n=1; unknown|Rep: UPI00015BC9A2 UniRef100 entry - unknown Length = 335 Score = 66.1 bits (154), Expect = 7e-10 Identities = 33/69 (47%), Positives = 46/69 (66%) Frame = +3 Query: 45 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 224 PIPEI DEVL+++ GIC SD+H G +V + P++ GHE +G+V K+GS VKN Sbjct: 19 PIPEIGPDEVLIKVKYCGICHSDLHIVD-GDWESWV-KLPVVPGHEVAGIVEKVGSNVKN 76 Query: 225 LTVGDRVAI 251 + GDRV + Sbjct: 77 VKEGDRVGM 85 Score = 35.9 bits (79), Expect = 0.88 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Frame = +2 Query: 245 GHRAGVP-----CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHV 409 G R G+P C C++C G LCP+ G Y K + F K+PD + Sbjct: 80 GDRVGMPWLYSSCEICDYCVEGEEPLCPNHEITGITR-QGGYAEYMKAPSHFVTKIPDKL 138 Query: 410 TMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLG 508 + A L + ++A R + +V++ G Sbjct: 139 ELSYAAPLFCAGITVYAALVRLNLKPNELVVIQG 172 >UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing; n=19; Bacteria|Rep: Alcohol dehydrogenase, zinc-containing - Bacillus anthracis Length = 350 Score = 66.1 bits (154), Expect = 7e-10 Identities = 30/84 (35%), Positives = 42/84 (50%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C CE CK G Y++C ++F G Y D +PD +T E+GAL+EP A Sbjct: 99 CGKCEACKHGHYNVCEQLVFHGLGGEGGGFSEYTVVPEDMVHHIPDEMTYEQGALVEPAA 158 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 V +HA ++ + G V V G P Sbjct: 159 VAVHAVRQSKLKEGEAVAVFGCGP 182 Score = 59.3 bits (137), Expect = 8e-08 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 7/102 (6%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC-----GHFV--LEEP 164 L + D+R+ + P P + V +++ GICG+D+H + G H + ++ P Sbjct: 5 LWHNQRDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAP 64 Query: 165 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 +I+GHE SG V +IG V + VGDRV +EP G + + Sbjct: 65 VILGHEFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACK 106 >UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protein; n=2; Bacteria|Rep: Alcohol dehydrogenase GroES-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 357 Score = 66.1 bits (154), Expect = 7e-10 Identities = 34/82 (41%), Positives = 48/82 (58%), Gaps = 1/82 (1%) Frame = +3 Query: 3 ALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A +Y+ P +LR+ P+PEI +VL+R+ GICGSD+H ++ G + IMGH Sbjct: 9 AAVYRGPRELRVEPVPVPEIGPSDVLVRVHSCGICGSDLHSYKAG----MYIRPGQIMGH 64 Query: 180 EASGVVAKIGSKVKNLTVGDRV 245 E G VA G V+ + GDRV Sbjct: 65 EFMGTVAAAGEDVEGVEEGDRV 86 Score = 41.9 bits (94), Expect = 0.013 Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Frame = +2 Query: 191 SSGQDRFESQESDSW*SSGHRAGVPCRYCEFCKTGRYHLCPDMIFCATP-PVHGNLVRYY 367 ++G+D +E D +G GV C C +C +Y LCP++ +T + G Y Sbjct: 72 AAGEDVEGVEEGDR--VTGFSIGV-CGSCYWCSRQQYILCPELFRNSTGYGLPGGFAEYV 128 Query: 368 --KHAA--DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLG 508 ++A +P + E A EP++VG+ A + GV G V+VLG Sbjct: 129 PIRNAVVGQSIHPVPSELDDETAATTEPVSVGVGAIEAAGVRPGDRVVVLG 179 >UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Acidiphilium cryptum JF-5|Rep: Alcohol dehydrogenase GroES domain protein - Acidiphilium cryptum (strain JF-5) Length = 339 Score = 66.1 bits (154), Expect = 7e-10 Identities = 32/86 (37%), Positives = 42/86 (48%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC +CE+C G +LCPD +F PP G + K+P H T+EE +LEP Sbjct: 89 MPCGHCEWCHRGEINLCPDTVFNGAPPYPGAMAERMAIEPRQVVKVPQHFTIEETMMLEP 148 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 L V IHA V V+G P Sbjct: 149 LGVAIHAIDLARPRLLESVAVIGCGP 174 Score = 58.4 bits (135), Expect = 1e-07 Identities = 27/83 (32%), Positives = 46/83 (55%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 D+ + P P D + + + VG+CGSD+HY+ +G G V+ EP + GHE + V + Sbjct: 11 DITIGDAPEPVPGNDRIAVEVAGVGVCGSDLHYYLEGSIGSQVIVEPFVPGHEFAARVIE 70 Query: 204 IGSKVKNLTVGDRVAIEPACRVG 272 ++ L G+ +A++PA G Sbjct: 71 ARPEL-GLAKGELIAVDPAMPCG 92 >UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=2; Acidobacteria|Rep: Alcohol dehydrogenase, zinc-binding - Acidobacteria bacterium (strain Ellin345) Length = 345 Score = 65.7 bits (153), Expect = 1e-09 Identities = 38/129 (29%), Positives = 67/129 (51%), Gaps = 2/129 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+LY D+R+ + P+P++ E E+L+++ CG+DV +++G ++ P + GHE Sbjct: 4 AVLYGKEDVRIEKVPVPKVGEGEILVKVQVALTCGTDVKVYRRGYHARMIV-PPALFGHE 62 Query: 183 ASGVVAKIGSKVKNLTVGDR-VAIEPA-CRVGTASSVRQDDTTYALT*SSAPRPQYTETS 356 +G+V ++G VK L G R VA+ A C V S Q++ L ++ +Y Sbjct: 63 LAGIVEEVGPGVKRLKKGMRVVALNSAPCGVCFYCSKHQENLCEDLLFNNGAYAEYILIP 122 Query: 357 SDITSTQLI 383 I L+ Sbjct: 123 KRIVEKNLL 131 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF-CFKLPDHVTMEEGALLEP 439 PC C +C + +LC D++F + + K + +PD V+ +E A++EP Sbjct: 90 PCGVCFYCSKHQENLCEDLLF--NNGAYAEYILIPKRIVEKNLLVIPDGVSFDEAAVIEP 147 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 LA + G+ G + V+G P Sbjct: 148 LACVLRGLHETGMEVGDTITVIGAGP 173 >UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12; Bacteria|Rep: Mannitol dehydrogenase - Leuconostoc mesenteroides Length = 338 Score = 65.3 bits (152), Expect = 1e-09 Identities = 34/80 (42%), Positives = 46/80 (57%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 230 P++ +EVL+ GICG+D H G G P+++GHE SGVVA+IGS V N+ Sbjct: 20 PKVLPNEVLIHTAFAGICGTD-HALYAGLPGSADAVPPIVLGHENSGVVAEIGSAVTNVK 78 Query: 231 VGDRVAIEPACRVGTASSVR 290 VGDRV ++P G R Sbjct: 79 VGDRVTVDPNIYCGQCKYCR 98 Score = 46.0 bits (104), Expect = 8e-04 Identities = 20/81 (24%), Positives = 41/81 (50%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C++C+T R LC ++ G ++ A + +PD+V+++ A++EP++ Sbjct: 91 CGQCKYCRTARPELCENLSAVGVTR-DGGFEEFFTAPASVVYPIPDNVSLKSAAVVEPIS 149 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 +H + V+ LV+G Sbjct: 150 CAVHGIQLLKVTPYQKALVIG 170 >UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4; Rhizobiales|Rep: Alcohol dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 341 Score = 64.9 bits (151), Expect = 2e-09 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A LY P DLR+ P I + V LR+D GICGSD+H ++ GQ ++ P GH Sbjct: 4 ARLYGPGDLRVEDVAPPGIPDPGWVKLRVDAAGICGSDLHNFRTGQ---WISRSPSTAGH 60 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIE 254 E +G V +G V + VGDRV + Sbjct: 61 ELTGTVTALGEGVDTVAVGDRVVAD 85 Score = 40.3 bits (90), Expect = 0.041 Identities = 28/88 (31%), Positives = 37/88 (42%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C+ GR HLC + F G A + + A+ EPLA Sbjct: 90 CEECVQCRAGRRHLCASLGFVGEV-CDGGFAEQVVLPARLLHVVDAALDERVAAMAEPLA 148 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASL 529 V +HA +R +AG VLV+G P L Sbjct: 149 VALHAVRRLPKTAGS-VLVVGCGPIGGL 175 >UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase; n=2; Clostridium difficile|Rep: Putative sugar-phosphate dehydrogenase - Clostridium difficile (strain 630) Length = 350 Score = 64.9 bits (151), Expect = 2e-09 Identities = 35/84 (41%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = +3 Query: 12 YKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 Y D R+ +P+I E D+V++++ GICGSD+ + K H V E I+GHE S Sbjct: 7 YGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISKYSKTG-PHMVGE---ILGHEFS 62 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPA 260 G VA++G +V++ +GDRVA+ PA Sbjct: 63 GEVAQVGKEVRSFKIGDRVAVCPA 86 Score = 56.0 bits (129), Expect = 8e-07 Identities = 27/86 (31%), Positives = 38/86 (44%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC C+ CK G Y C ++ + G Y K K+PD ++ E A LEP Sbjct: 87 MPCFECDECKKGLYSRCNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEP 146 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 + + H R G V+VLG P Sbjct: 147 VCIAGHGLFRSEAKVGDTVVVLGTGP 172 Score = 37.1 bits (82), Expect = 0.38 Identities = 17/41 (41%), Positives = 25/41 (60%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAE 663 AK FG+ K++ +D+ +LD AK LGAD + K+ N E Sbjct: 181 AKIFGSTKIIAVDVFDEKLDLAKELGAD-ICINAKEKNIVE 220 >UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain protein; n=2; Oceanospirillales|Rep: Alcohol dehydrogenase GroES domain protein - Marinomonas sp. MWYL1 Length = 340 Score = 64.9 bits (151), Expect = 2e-09 Identities = 37/90 (41%), Positives = 50/90 (55%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 ND L+ T P EVL++ GICGSD+H GQ FV + P I GHE SGVVA Sbjct: 10 NDYALIDTLQPVAEAGEVLIKTAFAGICGSDLHIIH-GQ-NPFV-QFPRITGHEFSGVVA 66 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 +G V ++ +GD+V ++P G + R Sbjct: 67 AVGEGVTHVKIGDKVCVDPVISCGECYACR 96 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/83 (27%), Positives = 39/83 (46%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C C C+ GR+++C + +G + A LPD+VT+E+ AL+EP Sbjct: 87 ISCGECYACRAGRFNVCAKLQVFGVHR-NGGFGEFTSAPASNVLVLPDNVTLEQAALVEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLG 508 ++ + R G +LV G Sbjct: 146 YSIATNVLSRMEPIPGDTLLVYG 168 Score = 33.9 bits (74), Expect = 3.6 Identities = 14/27 (51%), Positives = 20/27 (74%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGA 621 AKA G ++++ DI+ RL+ AKSLGA Sbjct: 180 AKAMGIERIIVTDIVDERLETAKSLGA 206 >UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=1; Halothermothrix orenii H 168|Rep: Zinc-containing alcohol dehydrogenase superfamily - Halothermothrix orenii H 168 Length = 336 Score = 64.5 bits (150), Expect = 2e-09 Identities = 29/84 (34%), Positives = 52/84 (61%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 + Y P ++++ IP+I E+EVL+++ GICG+D H ++ G +I+GHE Sbjct: 5 VFYGPGNVKIEDKEIPKIDENEVLVKVKAAGICGTDRHIYR----GEAPARTQVILGHEN 60 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 +G + + G +V++L GD+V I+P Sbjct: 61 AGEIIETGRQVRSLKKGDKVCIDP 84 Score = 51.2 bits (117), Expect = 2e-05 Identities = 25/81 (30%), Positives = 40/81 (49%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C G HLC ++ +G Y A +K+ ++V+ +E AL+EPLA Sbjct: 88 CGQCYYCHRGEVHLCKELQAIGVTR-NGGFAEYLVAPATNVYKVKENVSYKEMALVEPLA 146 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 +H G+ G V++LG Sbjct: 147 CCLHGIDLAGIRPGDFVVILG 167 >UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Novosphingobium aromaticivorans (strain DSM 12444) Length = 347 Score = 64.5 bits (150), Expect = 2e-09 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 179 A ++ P D+RL + P+P E L+++ G+CGSD+ Y +G G L P+ +GH Sbjct: 10 ARVHGPGDVRLDEVPVPHCGPGEALVQVAACGVCGSDLGYIAQGGLGGVEPLSAPLPIGH 69 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 E +G V +G V ++ G RVA+ P Sbjct: 70 EFAGTVVAVGQCVTSVAPGMRVAVNP 95 Score = 41.5 bits (93), Expect = 0.018 Identities = 17/43 (39%), Positives = 24/43 (55%) Frame = +2 Query: 389 FKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 F LPDH+ E +L EPL+VG+H + G + +LG P Sbjct: 125 FPLPDHLPFAEASLAEPLSVGLHGLRVAGAKTEDRIAILGAGP 167 >UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol dehydrogenase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative zinc-binding alcohol dehydrogenase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 334 Score = 64.5 bits (150), Expect = 2e-09 Identities = 37/89 (41%), Positives = 49/89 (55%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 ++ D+RL +PE ++ EVLLR+ VGICGSD+HY+ G+ G V+ EP GHE S Sbjct: 6 IHGAEDMRLEDVAVPEPADGEVLLRVRYVGICGSDLHYYFHGKNGENVVREPFAPGHEFS 65 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVGT 275 V S G V + PA R GT Sbjct: 66 ATVEADPS--GQWAKGTPVTVHPA-RYGT 91 Score = 37.1 bits (82), Expect = 0.38 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Frame = +2 Query: 392 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQL--KPLEH 559 +LP+ +++ + AL EPL V +HA G G LVLG P L + L + +EH Sbjct: 135 RLPEGLSLRDAALAEPLGVALHALTIAGGHLGDRALVLGAGPVGLLIVAALAARGVEH 192 Score = 33.5 bits (73), Expect = 4.7 Identities = 18/34 (52%), Positives = 22/34 (64%) Frame = +1 Query: 547 AFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKD 648 A G V DI +S LD A++LGA TLLIG+D Sbjct: 187 ARGVEHVAAGDIQESALDRARALGAHETLLIGRD 220 >UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4; Leptospira|Rep: Zinc binding dehydrogenase - Leptospira interrogans serogroup Icterohaemorrhagiae serovarcopenhageni Length = 348 Score = 64.1 bits (149), Expect = 3e-09 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 2/91 (2%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG--QCGHFVLEEPMIMGHEASGVVA 200 L + +P++ ++V +R+ GICGSDVH G +C HF P + GHE+SG++ Sbjct: 18 LEIRDVSVPQLRAEQVKVRIKACGICGSDVHLVVHGTLKCKHF----PRVPGHESSGIIE 73 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 ++G V+ GDRV I G S ++ Sbjct: 74 EVGENVRRFRKGDRVVIAAGTSCGVCSYCKE 104 Score = 44.4 bits (100), Expect = 0.003 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Frame = +2 Query: 254 AGVPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 AG C C +CK G+ +LC D+ +F G+ + + + LPD + ++GA+ Sbjct: 92 AGTSCGVCSYCKEGKENLCKDLGVFGFDR--DGSFAEFNIVEERYLYSLPDEIPFDQGAI 149 Query: 431 L-EPLAVGIHACK-RGGVSAGHVVLVLG 508 L + ++ HA + RG + V + G Sbjct: 150 LADAVSTPYHAIRYRGNIQESDTVAIFG 177 >UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2; Acidobacteria|Rep: Alcohol dehydrogenase GroES-like - Acidobacteria bacterium (strain Ellin345) Length = 374 Score = 64.1 bits (149), Expect = 3e-09 Identities = 35/81 (43%), Positives = 45/81 (55%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ + ND+RL P+PEI EVL+R+ GICG+D+ G H P I GHE Sbjct: 22 AVYHGLNDVRLETVPVPEIGRGEVLIRVASCGICGTDLKKISTG--SH---SAPRIFGHE 76 Query: 183 ASGVVAKIGSKVKNLTVGDRV 245 +GV+A G V VGDRV Sbjct: 77 TAGVIAAAGDGVTKFQVGDRV 97 Score = 36.3 bits (80), Expect = 0.67 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 10/94 (10%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDM----IFCATPPVHGNLVRYYKHAADFCF------KLPDHV 409 +PC+ C +C+ + CP + P G Y + D+ KLPDHV Sbjct: 103 IPCQECYYCRHKVFAQCPTYKKVGVTAGYEPSGGGFSEYVR-VMDWIVDRGGVVKLPDHV 161 Query: 410 TMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGR 511 + + +EP+ A + + +G VLV+G+ Sbjct: 162 SYDLATFVEPVNTCQKAIETMALKSGETVLVIGQ 195 >UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Alcohol dehydrogenase GroES domain protein - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 324 Score = 64.1 bits (149), Expect = 3e-09 Identities = 33/96 (34%), Positives = 54/96 (56%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ Y DLR+ + +P + + E+L+++ GICG+DVH + G+ G + P+I+GHE Sbjct: 4 AVFYGKRDLRVEEFDLPPLKQGEILVKVKACGICGTDVHIF-NGEKGSAKVTPPIILGHE 62 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 G V + S + VGD+V+I+P G R Sbjct: 63 FCGEVVETKSSL--FKVGDKVSIDPNIYCGVCRFCR 96 Score = 41.9 bits (94), Expect = 0.013 Identities = 26/94 (27%), Positives = 39/94 (41%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C FC++G+ LC + ++G Y D + EE AL EPLA Sbjct: 89 CGVCRFCRSGKVQLCESLTALGV-NLNGGFAEYAIVPEKQAILFED-IEFEEAALAEPLA 146 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 +H K+ + VL++G P + LK Sbjct: 147 CCLHGIKKLEIKPIDKVLIIGLGPIGLIMLEILK 180 >UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain protein; n=9; Actinomycetales|Rep: Alcohol dehydrogenase GroES domain protein - Mycobacterium sp. (strain KMS) Length = 343 Score = 64.1 bits (149), Expect = 3e-09 Identities = 31/84 (36%), Positives = 45/84 (53%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C FCK G LC + F V+G L RY F++PD +++ E A++EP+A Sbjct: 89 CGECGFCKQGAEALCGAVGFIGFA-VNGALARYASLPTKALFRIPDEISLAEAAVVEPIA 147 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 HA +R G++AG V + G P Sbjct: 148 SAYHAVRRSGLAAGGTVFIAGAGP 171 Score = 54.0 bits (124), Expect = 3e-06 Identities = 29/81 (35%), Positives = 45/81 (55%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ + D+R+ + P P EV++ + GICG+D+H + G H +++GHE Sbjct: 4 AIYHGREDVRIEELPDPSPRAGEVVIEVARAGICGTDLHEYIAGPM-HAA--PGVVIGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRV 245 SG V +GS V+ T GDRV Sbjct: 61 YSGTVVGVGSGVREFTEGDRV 81 >UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1; Parabacteroides distasonis ATCC 8503|Rep: Putative uncharacterized protein - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 347 Score = 63.7 bits (148), Expect = 4e-09 Identities = 33/84 (39%), Positives = 48/84 (57%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ DL+ P+P + DEVL+++ GICGSD+ K HF P ++GHE Sbjct: 5 VLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHF----PTVIGHEF 60 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SGVV+ IGS +G RV++ P Sbjct: 61 SGVVSDIGSSTYLSWLGKRVSVFP 84 Score = 59.3 bits (137), Expect = 8e-08 Identities = 30/82 (36%), Positives = 40/82 (48%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 PC C CK Y LC + + + +G Y ++PD V EE A+LEP Sbjct: 87 PCFKCNNCKNKEYELCSNYDYLGSR-CNGGFAEYVAVPVWNLLEIPDCVCYEEAAMLEPA 145 Query: 443 AVGIHACKRGGVSAGHVVLVLG 508 AV +HA KR G G V+V+G Sbjct: 146 AVALHALKRSGFKKGDTVVVIG 167 >UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain protein; n=2; Pseudomonas|Rep: Alcohol dehydrogenase GroES domain protein - Pseudomonas mendocina ymp Length = 422 Score = 63.7 bits (148), Expect = 4e-09 Identities = 31/90 (34%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Frame = +3 Query: 24 DLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 D+RL + P P++ + + ++R+ ICG+D+H+ +G G + + I+GHEA G+V Sbjct: 11 DIRLDEVPEPQVQASTDAVIRITASAICGTDLHF-VRGTVGG--MRKGTILGHEAVGIVE 67 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 +GS V+NL++GDRV + G + R Sbjct: 68 ALGSDVRNLSIGDRVVVPSTIACGNCAYCR 97 >UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Zinc-binding dehydrogenase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 336 Score = 63.7 bits (148), Expect = 4e-09 Identities = 29/81 (35%), Positives = 46/81 (56%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C YC C++G +LC + V+G Y A C+++PD +T E+GAL+EP++ Sbjct: 90 CGYCTPCRSGHGNLCANWN-ATGDTVNGAFAEYVSVPAATCYRMPDEMTWEQGALVEPVS 148 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 +H ++ GV AG LV+G Sbjct: 149 CAVHGVRQIGVEAGERFLVVG 169 Score = 57.6 bits (133), Expect = 3e-07 Identities = 31/98 (31%), Positives = 54/98 (55%), Gaps = 2/98 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 179 A++ +P +R+ P E +V++++ GICG+D+H GHF P++ GH Sbjct: 4 AIVDRPGSVRVGDVQDPSPGERDVVIKVGACGICGTDLHIAD----GHFPPTPYPIVPGH 59 Query: 180 EASGVVAKIGSKVK-NLTVGDRVAIEPACRVGTASSVR 290 E +G V ++GS+ +GDRVA++P+ G + R Sbjct: 60 EFAGEVVELGSEAPGGFEIGDRVAVDPSLFCGYCTPCR 97 >UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative zinc-containing alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative zinc-containing alcohol dehydrogenase - Nasonia vitripennis Length = 339 Score = 63.3 bits (147), Expect = 5e-09 Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE--EPMIMGHEASGVVA 200 L L + IP+ +DEVL+R+ GICG+D+H + G F + EP+I GHE G V Sbjct: 13 LTLQKASIPKPKDDEVLIRVAYSGICGTDLHILE----GTFPCKQNEPLIPGHEFCGTVE 68 Query: 201 KIGSKVKNLTVGDRVAIEP 257 +G VKN VG RV ++P Sbjct: 69 AVGVSVKNFKVGQRVTVDP 87 Score = 42.3 bits (95), Expect = 0.010 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 C C+ C G YHLC + +T + +G + + +P+ V ME+ AL EP Sbjct: 91 CSMCDDCHVGCYHLCVNGGVNSTIGIFRNGGWATHCCVPEVQVYHVPEGVEMEQAALSEP 150 Query: 440 LAVGIHACKR-GGVSAGHVVLVLG 508 L+ H KR + G VLVLG Sbjct: 151 LSCLAHGWKRMNPIHVGQKVLVLG 174 >UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep: Tll0970 protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 373 Score = 63.3 bits (147), Expect = 5e-09 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 179 A+LY D+R+ P P EV++R+ CG+D+ W++G GH +L P++ GH Sbjct: 28 AVLYGKEDVRIETVPDPTPGPGEVVIRVRAATTCGTDLKVWRRG--GHARMLTPPILFGH 85 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 EA+G + +G+ V VGDRV + G Sbjct: 86 EAAGEIVALGAGVTGWQVGDRVVANNSAPCG 116 Score = 35.9 bits (79), Expect = 0.88 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 4/75 (5%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF----CFKLPDHVTMEEGAL 430 PC C +C+ + LCP + F +G Y K A +P+ + AL Sbjct: 114 PCGQCFYCQRQAFSLCPHLEF-----NNGTFAEYLKLPASIVRQNLLPIPESLPFALAAL 168 Query: 431 LEPLAVGIHACKRGG 475 EPLA +H R G Sbjct: 169 TEPLACVLHGVARSG 183 >UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase; n=1; Bacillus clausii KSM-K16|Rep: Galactitol-1-phosphate 5-dehydrogenase - Bacillus clausii (strain KSM-K16) Length = 352 Score = 63.3 bits (147), Expect = 5e-09 Identities = 29/74 (39%), Positives = 49/74 (66%) Frame = +3 Query: 36 VQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 215 ++TP+P+ EDE L+++ GICGSD+ + G+ ++ P+++GHE SG V +G+ Sbjct: 17 IETPVPK--EDEALIKVAYCGICGSDLARYFDGKVHNY----PIVLGHEFSGTVEAVGAS 70 Query: 216 VKNLTVGDRVAIEP 257 V ++ VGDRV + P Sbjct: 71 VDSVAVGDRVVVAP 84 Score = 43.2 bits (97), Expect = 0.006 Identities = 23/55 (41%), Positives = 31/55 (56%) Frame = +2 Query: 344 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLG 508 +G + Y A+ LP+ VT+ E AL+EPL V IH +R + AG V VLG Sbjct: 113 NGAMAEYVVVKAENLLVLPETVTLAEAALIEPLTVAIHGIERIVLPAGEHVCVLG 167 Score = 33.5 bits (73), Expect = 4.7 Identities = 17/30 (56%), Positives = 20/30 (66%) Frame = +1 Query: 544 KAFGAHKVLIIDILQSRLDFAKSLGADYTL 633 KA GA KV IDI +L FAK +GAD T+ Sbjct: 180 KARGAGKVTAIDINDEKLAFAKKIGADDTI 209 >UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase, long-chain; n=1; Bacillus sp. B14905|Rep: Zinc-containing alcohol dehydrogenase, long-chain - Bacillus sp. B14905 Length = 339 Score = 63.3 bits (147), Expect = 5e-09 Identities = 31/97 (31%), Positives = 52/97 (53%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A Y D+R+ + +P + V +++ GICGSD+H + G + ++GHE Sbjct: 4 AKFYGMKDIRVEEAELPVLKNGMVKVKIAFAGICGSDLHEYVGGA---YAFRTQPVLGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 SGVV ++ V + VGDRVA+EP G ++ ++ Sbjct: 61 FSGVVVEVAEGVTHTKVGDRVAVEPPIPCGKCANCKR 97 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPD-MIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 +PC C CK G +LC + T + G Y + + LP+ +++E GAL+E Sbjct: 87 IPCGKCANCKRGYSNLCKSGQSYGYT--ISGGFAEYAVVREENIYHLPEGMSLELGALVE 144 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 P AV +HA ++ + G + G P L +K Sbjct: 145 PTAVAVHAVRQSQLKLGDTAAIFGAGPIGLLILQAVK 181 >UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol dehydrogenase GroES domain protein - Arthrobacter sp. (strain FB24) Length = 349 Score = 63.3 bits (147), Expect = 5e-09 Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMG 176 A L+ P ++R+ P P ++++R+ ICG+D G HF L E P ++G Sbjct: 4 ARLHSPGNIRVDDIPRPSADAGDIIIRVRAASICGTDRRIAANG---HFKLPEGTPRVLG 60 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEPACRVGT 275 HE +G + + GS+V VGDRV++ P GT Sbjct: 61 HEFAGEIVEAGSEVSGYAVGDRVSVTPNVGCGT 93 Score = 35.1 bits (77), Expect = 1.5 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGAD 624 AK +GA KV++ + Q RLDFA +LGAD Sbjct: 187 AKLYGARKVIVSNNRQPRLDFAGTLGAD 214 Score = 34.3 bits (75), Expect = 2.7 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 4/90 (4%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHG--NLVRYYKHAADF--CFKLPDHVTMEEGA 427 V C C C G ++CP G VR + A + F LP+ V E A Sbjct: 89 VGCGTCPNCLVGLNNMCPSYEAFGITMDGGFQEYVRIPRFALNRGNVFHLPETVGYAEAA 148 Query: 428 LLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 L+EPL+ +A + V VL++G P Sbjct: 149 LVEPLSCCYNAVSKLDVRPDSTVLIMGAGP 178 >UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellular organisms|Rep: L-threonine 3-dehydrogenase - Thermoanaerobacter tengcongensis Length = 347 Score = 63.3 bits (147), Expect = 5e-09 Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 8/97 (8%) Frame = +3 Query: 12 YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 191 Y +V+ IP+I DEVL+++ ICG+DVH + + ++ P MGHE G Sbjct: 12 YHKEGADIVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVG 71 Query: 192 VVAKIGSKVKNLTVGDRVAIEP--------ACRVGTA 278 V +IG V ++ VGD V+ E ACR G A Sbjct: 72 EVVEIGENVTSVKVGDLVSAETHIVCGKCRACRTGNA 108 Score = 37.5 bits (83), Expect = 0.29 Identities = 24/96 (25%), Positives = 38/96 (39%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C C C+TG H+C + + G Y K + ++ +E ++ EP Sbjct: 95 IVCGKCRACRTGNAHICENTLILGV-DTDGAFAEYIKVPESNVWINDKNIPLEILSIQEP 153 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 L +H G V G V V+G P + LK Sbjct: 154 LGNAVHTVFSGDV-VGKSVAVIGCGPIGMMAIPLLK 188 >UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n=7; cellular organisms|Rep: Probable L-threonine 3-dehydrogenase - Pyrococcus horikoshii Length = 348 Score = 63.3 bits (147), Expect = 5e-09 Identities = 29/87 (33%), Positives = 50/87 (57%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 LV+ +P+ EVL+++ ICG+D+H ++ + ++ P IMGHE +G V +IG Sbjct: 19 LVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGP 78 Query: 213 KVKNLTVGDRVAIEPACRVGTASSVRQ 293 V+ + VGD V++E G + R+ Sbjct: 79 GVEGIEVGDYVSVETHIVCGKCYACRR 105 Score = 37.9 bits (84), Expect = 0.22 Identities = 24/86 (27%), Positives = 34/86 (39%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C C C+ G+YH+C + G Y A +K P + E L EP Sbjct: 95 IVCGKCYACRRGQYHVCQNTKIFGV-DTDGVFAEYAVVPAQNIWKNPKSIPPEYATLQEP 153 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 L + G +S G VL+ G P Sbjct: 154 LGNAVDTVLAGPIS-GKSVLITGAGP 178 >UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3; Caenorhabditis|Rep: Alcohol dehydrogenase 2 - Caenorhabditis elegans Length = 351 Score = 63.3 bits (147), Expect = 5e-09 Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 2/78 (2%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMGHEASGVVA 200 L + Q +P+ E+E+L++++ GIC SD+H W+ G F P+I GHE +G V Sbjct: 22 LEVRQVSVPQPQENELLVKIEYSGICHSDLHTWE----GDFEYASICPLIGGHEGAGTVV 77 Query: 201 KIGSKVKNLTVGDRVAIE 254 IGSKVK +GDR I+ Sbjct: 78 TIGSKVKGWNIGDRAGIK 95 >UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_03000847; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03000847 - Ferroplasma acidarmanus fer1 Length = 333 Score = 62.9 bits (146), Expect = 7e-09 Identities = 33/89 (37%), Positives = 49/89 (55%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L +P L L+ T + EV ++ GICG+D H + G+ H ++ P+I GHE Sbjct: 5 VLKEPGVLELINTEARKPDTGEVQIKTRACGICGTDFHAYN-GK--HLAVKYPVIPGHEF 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 SGV+ IG VK+ GDRV ++P G Sbjct: 62 SGVITSIGEGVKSFMPGDRVVVDPNITCG 90 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/83 (28%), Positives = 38/83 (45%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C CE+CK G+ + C + I G Y +K+PD ++ E A++EP Sbjct: 87 ITCGQCEYCKGGKENFCEN-IKTVGINYPGGYGEYVTVPEKVVYKIPDTMSFEAAAIVEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLG 508 +A IHA V G ++ G Sbjct: 146 VACIIHAFDNTHVPLGGSAIISG 168 >UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=17; Proteobacteria|Rep: Zinc-containing alcohol dehydrogenase superfamily - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 373 Score = 62.9 bits (146), Expect = 7e-09 Identities = 41/128 (32%), Positives = 59/128 (46%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C++G Y+LC M F G + + A +LPD V++E+ A++EP A Sbjct: 100 CSQCAYCRSGSYNLCVSMGFAGLMG-DGGMADFAVVPAYMLHRLPDGVSLEQAAVMEPAA 158 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTKYS**ISFRAVWISPSR*APT 625 V +HA +RG + G V G P L L L+ + AV +SP R A Sbjct: 159 VALHALRRGELRLGETCAVFGLGP-IGLLLIMLAKLQGA-----TTIVAVDVSPERLAAA 212 Query: 626 THFS*ART 649 T F T Sbjct: 213 TRFGATHT 220 Score = 60.5 bits (140), Expect = 4e-08 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 8/99 (8%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIM 173 P D+RLV+ P + +V + + GICGSD+H + G H + P+ + Sbjct: 9 PRDVRLVEIDTPRVGPGDVRIAVAYCGICGSDLHEYADGPHAIPVDTPHPLSRRTAPLTL 68 Query: 174 GHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 GHE G V ++G V L GDRVA+EP R + R Sbjct: 69 GHEFCGTVVEVGEGVTALRAGDRVAVEPEYRCSQCAYCR 107 >UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 319 Score = 62.9 bits (146), Expect = 7e-09 Identities = 33/84 (39%), Positives = 48/84 (57%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ +DLRL + +P +S EVL+R+ C GIC SDV H+ P+I+GHE Sbjct: 11 VLHNIDDLRLSEVKLPVLSRGEVLVRVKCAGICSSDVQRVFVSGAYHY----PIILGHEF 66 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SG+V K S + +G RV + P Sbjct: 67 SGIVEKAYSDAEASWIGKRVGVYP 90 >UniRef50_Q11VP8 Cluster: Zinc-type alcohol dehydrogenase; n=2; Sphingobacteriales|Rep: Zinc-type alcohol dehydrogenase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 385 Score = 62.9 bits (146), Expect = 7e-09 Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 1/84 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A+ +KP + + P+I + D+++L++ ICGSD+H + G F P+IMGH Sbjct: 4 AVFHKPGHISVDTVEDPKIEKSDDIILKVTSTAICGSDLHIYD----GFFPQARPLIMGH 59 Query: 180 EASGVVAKIGSKVKNLTVGDRVAI 251 E G+V ++G+ V +L GDR+ + Sbjct: 60 EFMGIVEEVGNAVTHLKAGDRIVV 83 >UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenase; n=3; Bacteria|Rep: Probable zinc-type alcohol dehydrogenase - Rhodopirellula baltica Length = 396 Score = 62.5 bits (145), Expect = 9e-09 Identities = 29/82 (35%), Positives = 46/82 (56%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P + + + PEI +VLL + VG+CGSD+H W + + P+++GHE G Sbjct: 66 EPGSVEIREIDRPEIGSQDVLLEVSHVGVCGSDLHQWTAHH--SWPVNYPVVLGHEFGGH 123 Query: 195 VAKIGSKVKNLTVGDRVAIEPA 260 + ++GS V+ GDRV E A Sbjct: 124 IVQLGSDVEGWKEGDRVVSETA 145 >UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 341 Score = 62.1 bits (144), Expect = 1e-08 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 179 A+L +P + + IPEI +VL+R+ GICG+D+H + GH+ + P++ GH Sbjct: 4 AVLVEPRRFEVREVGIPEIGPADVLIRVTRAGICGTDLHIFN----GHYAADRLPIVPGH 59 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIE 254 E G +A+IG+ V +L G RV + Sbjct: 60 EFCGTIAEIGASVTHLKTGMRVVAD 84 Score = 33.9 bits (74), Expect = 3.6 Identities = 22/96 (22%), Positives = 39/96 (40%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C C +C+ C ++ G +Y +PD V AL+EP Sbjct: 87 IGCGNCYWCRRNEVLNCGEVEQIGIGR-DGAFAQYVALPGRLVLPVPDGVPEAVLALVEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 +A + A ++ G + G +VLG P +L ++ Sbjct: 146 VACVVRAARKAGAAFGRSGVVLGAGPIGNLHVQMMR 181 >UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol dehydrogenase GroES domain protein - Arthrobacter sp. (strain FB24) Length = 344 Score = 62.1 bits (144), Expect = 1e-08 Identities = 37/102 (36%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +3 Query: 3 ALLYKPND-LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP----M 167 AL + D + +V +PE E++L + G+CGSD+HY+ +P M Sbjct: 7 ALRFAEKDRVSVVDAALPEAGPGEIVLDVKAAGLCGSDLHYFHMTHNQMQNATQPRSPEM 66 Query: 168 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 GHE +GVVA IG V + +VGDRVAI+ GT + R+ Sbjct: 67 TPGHEIAGVVASIGPGVTHPSVGDRVAIQHYSGCGTCETCRK 108 >UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 353 Score = 62.1 bits (144), Expect = 1e-08 Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 7/94 (7%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCG-----HFVL--EEPMIMGHE 182 D+R+ Q P +E +V +R VGICGSD+H + G H + + P+ +GHE Sbjct: 11 DIRVDQIDEPSCAEGQVKIRPAFVGICGSDLHEYLSGPIAIPTTPHPLTGAQLPVTLGHE 70 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASS 284 SG + ++G V VGDRVA+ P GT +S Sbjct: 71 FSGTIEEVGQGVTGFKVGDRVAVRPNLSDGTCAS 104 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/81 (33%), Positives = 34/81 (41%) Frame = +2 Query: 275 CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGI 454 C C GR + C + F G L Y A LP+ V ++ GAL+EPL V Sbjct: 102 CASCVYGRPNCCRSLGFIGFSSNSGGLSDYVTVPAKHAILLPESVPLDLGALVEPLTVAW 161 Query: 455 HACKRGGVSAGHVVLVLGRDP 517 HA R LV+G P Sbjct: 162 HAVARSPHETARTALVVGGGP 182 >UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41; Bacteria|Rep: L-threonine 3-dehydrogenase - Yersinia pestis Length = 341 Score = 62.1 bits (144), Expect = 1e-08 Identities = 27/86 (31%), Positives = 46/86 (53%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 + P PE+ +++++++ ICG+DVH + + + PM++GHE G V IG Sbjct: 15 MTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQ 74 Query: 213 KVKNLTVGDRVAIEPACRVGTASSVR 290 +VK +GDRV+ E G + R Sbjct: 75 EVKGFNIGDRVSGEGHITCGHCRNCR 100 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/86 (29%), Positives = 39/86 (45%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C +C C+ GR HLC + + G+ Y A FK+PD+++ E A+ +P Sbjct: 91 ITCGHCRNCRGGRTHLCRNTVGVGVNRP-GSFAEYLVIPAFNAFKIPDNISDELAAIFDP 149 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 +H + G VLV G P Sbjct: 150 FGNAVHTALSFDL-VGEDVLVSGAGP 174 >UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24; Proteobacteria|Rep: 2,3-butanediol dehydrogenase - Pseudomonas aeruginosa Length = 363 Score = 61.7 bits (143), Expect = 2e-08 Identities = 30/81 (37%), Positives = 44/81 (54%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C+ G Y++C ++ F +G Y A+ + LP E GAL+EPLA Sbjct: 111 CGTCYYCRHGLYNICENLAFTGLMN-NGAFAEYVNVPANLLYALPAGFPSEAGALIEPLA 169 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 VG+HA K+ G G V+V+G Sbjct: 170 VGMHAVKKAGSLLGQNVVVVG 190 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 9/100 (9%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFV--L 155 A+ + +D+R+ P+P E V +R+ GICGSD+H + G + H + L Sbjct: 14 AVWHGRHDIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGL 73 Query: 156 EEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGT 275 ++ I+GHE SG + ++G+ V VG VA + GT Sbjct: 74 KDQCILGHEFSGEIVRLGNGVTGFAVGQAVAADACQHCGT 113 >UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related Zn-dependent dehydrogenases; n=1; Pelotomaculum thermopropionicum SI|Rep: Threonine dehydrogenase and related Zn-dependent dehydrogenases - Pelotomaculum thermopropionicum SI Length = 343 Score = 61.7 bits (143), Expect = 2e-08 Identities = 33/96 (34%), Positives = 51/96 (53%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P + L P P + DEVL+R+ +CGSD+H ++ + F ++ P+I+GHE SG Sbjct: 10 RPGAVNLRSVPEPRPAGDEVLIRVQSAAVCGSDLHAYEYPKSYEF-MKVPVILGHEYSGY 68 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDT 302 V +G +V GDRV E G + R+ T Sbjct: 69 VEAVGPQVTLFKPGDRVLGESNRYCGVCPNCRRGRT 104 >UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Thermosinus carboxydivorans Nor1|Rep: Alcohol dehydrogenase GroES domain protein - Thermosinus carboxydivorans Nor1 Length = 340 Score = 61.7 bits (143), Expect = 2e-08 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 1/95 (1%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 191 KP L + + P+P EV++++ GICGSDVH + GQ + P I+GHEA G Sbjct: 8 KPGQLTVGERPMPAAPVGGEVVVKIKAAGICGSDVHIFH-GQ--NPFATYPRILGHEAVG 64 Query: 192 VVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQD 296 V + G++VK+L GDRVAI+ G + R + Sbjct: 65 EVYQAGAEVKDLKPGDRVAIDNVFSCGRCYACRSN 99 Score = 49.6 bits (113), Expect = 7e-05 Identities = 26/84 (30%), Positives = 40/84 (47%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C++ R+++C ++ + G Y K AD +KLP + E A +EP + Sbjct: 90 CGRCYACRSNRHNVCREVKVLGVH-IDGVFQEYIKITADKLYKLPADLPWEMAATVEPYS 148 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 + A R GV+ VLV G P Sbjct: 149 IAAEAVDRAGVTKDDTVLVCGAGP 172 >UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; Clostridium cellulolyticum H10|Rep: Alcohol dehydrogenase GroES-like - Clostridium cellulolyticum H10 Length = 348 Score = 61.7 bits (143), Expect = 2e-08 Identities = 36/84 (42%), Positives = 50/84 (59%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L+ +DLR + P + EVL+R+ GICGSD+ G HF P+++GHE Sbjct: 5 VLHARDDLRYEEILTPVPVKGEVLVRVKATGICGSDIPR-VLGDGAHFF---PIVLGHEF 60 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEP 257 SG VA+IG V ++ VGDRVA P Sbjct: 61 SGEVAEIGEGVTSVAVGDRVAGVP 84 Score = 48.0 bits (109), Expect = 2e-04 Identities = 27/83 (32%), Positives = 34/83 (40%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 VPC C C+ G Y LC F + G+ Y K K D V+ E+GA EP Sbjct: 86 VPCLKCGDCQKGDYALCKHYSFIGSRE-SGSFAEYVKMPERNVVKFNDSVSFEQGAFFEP 144 Query: 440 LAVGIHACKRGGVSAGHVVLVLG 508 V +H G V +LG Sbjct: 145 ATVALHGLLCADYRGGEDVAILG 167 Score = 34.7 bits (76), Expect = 2.0 Identities = 18/40 (45%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTL-LIGKDSNE 657 A+ FGA +V + DI RL AK LG D T+ + KD E Sbjct: 179 ARIFGAKRVFVFDIDNDRLALAKKLGVDVTINTLDKDFKE 218 >UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 347 Score = 61.7 bits (143), Expect = 2e-08 Identities = 30/90 (33%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Frame = +3 Query: 27 LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 L ++ P+P +S EV++++ GIC D+ + G + +++GHE SGVV+ Sbjct: 12 LSVITRPVPHVSNPSEVIVKVAYSGICDRDLQILE----GELPAAKCVVLGHEFSGVVSD 67 Query: 204 IGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 +GS VKN+++GDRV + P T + R+ Sbjct: 68 VGSDVKNVSIGDRVVVNPNSSCNTCKACRR 97 >UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178; Bacteria|Rep: L-threonine 3-dehydrogenase - Deinococcus radiodurans Length = 348 Score = 61.7 bits (143), Expect = 2e-08 Identities = 29/86 (33%), Positives = 50/86 (58%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 +++T +P +++L+R+ ICG+DVH ++ + PM++GHE GVVA +GS Sbjct: 15 MIETEVPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPVPMVVGHEYVGVVAGMGS 74 Query: 213 KVKNLTVGDRVAIEPACRVGTASSVR 290 +V+ +GDRV+ E G + R Sbjct: 75 EVRGFEIGDRVSGEGHVTCGHCRNCR 100 Score = 41.9 bits (94), Expect = 0.013 Identities = 25/86 (29%), Positives = 36/86 (41%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C +C C+ GR HLC + G+ Y A FKLPD + + A+ +P Sbjct: 91 VTCGHCRNCRAGRRHLCRNTQGVGVNR-PGSFAEYLVLPAFNAFKLPDDIPDDVAAIFDP 149 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDP 517 +H + G VL+ G P Sbjct: 150 FGNAVHTALSFDL-VGEDVLITGAGP 174 >UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8; Bacteria|Rep: L-iditol 2-dehydrogenase - Bacillus halodurans Length = 348 Score = 61.3 bits (142), Expect = 2e-08 Identities = 31/94 (32%), Positives = 44/94 (46%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C CK G+Y+LC + F G Y K+PD V+ E+GAL+EP A Sbjct: 100 CGTCTACKQGKYNLCEQLGFLGLAGGGGGFSEYVTVDEHMVHKIPDTVSFEQGALVEPAA 159 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 V ++A ++ + G +V G P L LK Sbjct: 160 VALYAVRQSQFNVGDQAVVFGTGPIGLLVIEALK 193 Score = 60.9 bits (141), Expect = 3e-08 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 8/98 (8%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIMGH 179 D+R+ P + +V +++ GICGSD+H + G H + EE P++MGH Sbjct: 11 DVRVDDIAEPATLKGKVKIKVKWCGICGSDLHEYAAGPIFIPQNSPHSLTEEKAPIVMGH 70 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 E SG V ++G V GDRV +EP GT ++ +Q Sbjct: 71 EFSGQVVEVGDGVTKCEEGDRVVVEPIFACGTCTACKQ 108 >UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase; n=5; Bacillus|Rep: Zinc-containing alcohol dehydrogenase - Bacillus subtilis Length = 339 Score = 61.3 bits (142), Expect = 2e-08 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = +3 Query: 15 KPNDLRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 191 K DL + P +S +DEVL+++ VGICGSD+H + G L P ++GHE +G Sbjct: 8 KAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYH-GTNPLATL--PRVIGHEVTG 64 Query: 192 VVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 V +G+ V++L GD V IEP G+ + R+ Sbjct: 65 QVEAVGANVQSLKPGDHVVIEPISYCGSCYACRK 98 >UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus amyloliquefaciens FZB42|Rep: GutB1 - Bacillus amyloliquefaciens FZB42 Length = 348 Score = 60.9 bits (141), Expect = 3e-08 Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Frame = +3 Query: 3 ALLYKPND-LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 176 AL++ PND L + P+I + ++V +++ GICG+D++ + G MIMG Sbjct: 3 ALVWTPNDKLEYQEVDEPQIRKSNDVKVKIFGTGICGTDLNVLK----GKMNATHHMIMG 58 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT 317 HE+ G V +IG V N+ VGDRV I+P G R+ T Y T Sbjct: 59 HESVGAVVEIGPDVTNVKVGDRVVIDPTQFCGKCHYCRRGLTCYCET 105 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 1/97 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMI-FCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 C C +C+ G C + HG YY F +++PD + E L+EPL Sbjct: 89 CGKCHYCRRGLTCYCETFEDWQLGIGAHGTFAEYYVGEDRFMYRIPDSMEWERATLVEPL 148 Query: 443 AVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 + ++ + + VLVLG P L +K L Sbjct: 149 SCVLNVVDKASIQPEDSVLVLGSGPIGLLVQMMVKKL 185 >UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2; Comamonadaceae|Rep: Alcohol dehydrogenase GroES-like - Delftia acidovorans SPH-1 Length = 567 Score = 60.9 bits (141), Expect = 3e-08 Identities = 33/91 (36%), Positives = 50/91 (54%), Gaps = 5/91 (5%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEASGVVAK 203 L L Q +P EVLLR+ G+CG+D+H + + HF+ P+ +GHE SG +A Sbjct: 229 LTLTQADMPAPGPGEVLLRVHSAGVCGTDLHIAEWTRSYHFLTPALPVTIGHEFSGEIAA 288 Query: 204 IGSKVKN----LTVGDRVAIEPACRVGTASS 284 +G +N LTVG VA+ P+ G ++ Sbjct: 289 LGEGAENLAPGLTVGQMVAVRPSVTCGRCAA 319 Score = 39.5 bits (88), Expect = 0.072 Identities = 27/86 (31%), Positives = 34/86 (39%) Frame = +2 Query: 251 RAGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 R V C C C +G + C +G + C +P V + AL Sbjct: 309 RPSVTCGRCAACTSGNFDGCTTRRGIGVLR-NGGFAPWAAVPLRNCVPVPAGVQGDVAAL 367 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLG 508 EPL V A + GV GH VLVLG Sbjct: 368 AEPLTVSHEAVRTAGVRPGHRVLVLG 393 >UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protein; n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol dehydrogenase GroES-like protein - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 344 Score = 60.5 bits (140), Expect = 4e-08 Identities = 30/96 (31%), Positives = 51/96 (53%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 +++ P + + PE+ +VL+++ +GICGSD+H G+ H + P+ GHE Sbjct: 4 SVMVSPGKIEFHEVEKPELKPGQVLIKIMRIGICGSDIHV-NHGK--HPFTKYPVTQGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 SG + ++ V++L VG +V IEP G R Sbjct: 61 VSGKIVEVAEDVEHLKVGQKVTIEPQVVCGKCHPCR 96 Score = 60.1 bits (139), Expect = 5e-08 Identities = 33/96 (34%), Positives = 49/96 (51%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C C C+TG+Y+LC ++ V G Y+ A +PDH++ +E A++EP Sbjct: 87 VVCGKCHPCRTGKYNLCEELKVMGFQTV-GAGSEYFAVDAKNVTTVPDHLSYDEAAMIEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 LAV +HA R G ++V+G P L LK Sbjct: 146 LAVTVHAANRVGDVKDKDIVVIGAGPIGILLVQTLK 181 >UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3; Saccharomycetales|Rep: Glycerol dehydrogenase - Pichia angusta (Yeast) (Hansenula polymorpha) Length = 380 Score = 60.5 bits (140), Expect = 4e-08 Identities = 28/81 (34%), Positives = 39/81 (48%) Frame = +2 Query: 275 CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGI 454 C C++G + C + FC G Y + D KLPD + + GAL+EP++V Sbjct: 122 CMACQSGSPNCCASLSFCGLGGASGGFAEYVVYGEDHMVKLPDSIPDDIGALVEPISVAW 181 Query: 455 HACKRGGVSAGHVVLVLGRDP 517 HA +R G LVLG P Sbjct: 182 HAVERARFQPGQTALVLGGGP 202 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 13/96 (13%) Frame = +3 Query: 6 LLYKPNDLRLVQT-PIPEISE-DEVLLRMDCVGICGSDV-HYWQKGQCGHFV-------- 152 L Y ND+R +T P PEI ++V +++ GICG+D+ + G F Sbjct: 5 LYYGTNDIRYSETVPEPEIKNPNDVKIKVSYCGICGTDLKEFTYSGGPVFFPKQGTKDKI 64 Query: 153 --LEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIE 254 E P+ GHE SG V ++GS V ++ GDRVA+E Sbjct: 65 SGYELPLCPGHEFSGTVVEVGSGVTSVKPGDRVAVE 100 >UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6; Cyanobacteria|Rep: Sorbitol dehydrogenase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 366 Score = 60.1 bits (139), Expect = 5e-08 Identities = 31/77 (40%), Positives = 44/77 (57%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 N L + PIPEI+ DEVL+R+ VG+C SD+ + + + E P I GHE +G +A Sbjct: 26 NQLSYEEIPIPEIAADEVLVRVRVVGLCQSDIK-----KIRYPLYEPPRIFGHETAGEIA 80 Query: 201 KIGSKVKNLTVGDRVAI 251 +G V VG RV + Sbjct: 81 AVGDAVTGWQVGQRVVV 97 Score = 46.0 bits (104), Expect = 8e-04 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATP----PVHGNLVRYYK---HAADF--CFKLPDHVT 412 +PC +C +C Y +C T P G Y K H + +PD ++ Sbjct: 101 IPCMHCAYCLNENYSMCHVYKTVTTTAGFIPSGGGFAEYVKVPGHIVEHGGLIPIPDPIS 160 Query: 413 MEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 EE + +EP + A K+ G++ G VL+ G P Sbjct: 161 DEEASFVEPTNCCLKAVKKAGIAPGQTVLITGAGP 195 >UniRef50_Q3W6B4 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=1; Frankia sp. EAN1pec|Rep: Zinc-containing alcohol dehydrogenase superfamily - Frankia sp. EAN1pec Length = 358 Score = 60.1 bits (139), Expect = 5e-08 Identities = 31/73 (42%), Positives = 45/73 (61%), Gaps = 2/73 (2%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 230 P + +VL+R+ GIC +D+H GH L P++ GHEA GVV ++GS+V+ + Sbjct: 21 PAVGPRDVLVRIAASGICHTDLHVIN----GHSPLPLPIVPGHEACGVVEEVGSEVRRVK 76 Query: 231 VGDRV--AIEPAC 263 VG RV A+ PAC Sbjct: 77 VGQRVLAAVSPAC 89 >UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Zn-dependent alcohol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 347 Score = 60.1 bits (139), Expect = 5e-08 Identities = 30/80 (37%), Positives = 45/80 (56%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ +P + + P P+ +VLLR VGICGSD+H ++KG G IMGHE Sbjct: 4 AVYQRPGLIEVQDVPTPQPGPRDVLLRTRAVGICGSDLHVYRKGLYG---ATTGWIMGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDR 242 G ++G +V+ +VG+R Sbjct: 61 FCGEAVEVGEEVRGASVGER 80 Score = 33.9 bits (74), Expect = 3.6 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 5/86 (5%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADF-CFKLPDHVTMEEGAL 430 C C +C+ + LCP + T P V + D F +P ++ E AL Sbjct: 89 CGQCYWCQRNQQRLCPHLFEHYTGYGEPGAMAEYVLIRQAQLDQNLFAIPASLSDEAAAL 148 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLG 508 EPL ++ +R G V+V+G Sbjct: 149 AEPLGTAAYSVRRAKPQDGDTVVVIG 174 >UniRef50_A7H7S9 Cluster: Alcohol dehydrogenase GroES domain protein; n=7; cellular organisms|Rep: Alcohol dehydrogenase GroES domain protein - Anaeromyxobacter sp. Fw109-5 Length = 404 Score = 60.1 bits (139), Expect = 5e-08 Identities = 36/106 (33%), Positives = 59/106 (55%), Gaps = 2/106 (1%) Frame = +3 Query: 3 ALLYK-PNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 176 A+++K P + + + P I S +VL+R+ GICGSD+H ++ G V E +++G Sbjct: 3 AVVWKGPGKVAVEKVEDPRIESATDVLVRITTAGICGSDLHMYE----GRTVAEPGVVLG 58 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYAL 314 HE GV+ ++GS V+ L GDRV + GT + + T+ L Sbjct: 59 HENMGVIEEVGSAVQQLQKGDRVVLPFNVACGTCFNCSRGYTSACL 104 >UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protein precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol dehydrogenase GroES-like protein precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 341 Score = 59.7 bits (138), Expect = 6e-08 Identities = 32/85 (37%), Positives = 45/85 (52%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 P ++ + + P PE V+LR GICGS+V + G+ G+ P++MGHE SG V Sbjct: 9 PREMAVEEIPEPEAGPGAVVLRTGAAGICGSEVEGYL-GRMGNRT--PPLVMGHEFSGTV 65 Query: 198 AKIGSKVKNLTVGDRVAIEPACRVG 272 +G V VG RVA+ P G Sbjct: 66 VAVGEGVDEAWVGRRVAVNPLISCG 90 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVRYYKHAADFCFKLPDHVTMEEGALL 433 + C C C++G ++CP+ +H G Y + A LP+ V + AL Sbjct: 87 ISCGECRLCRSGHENICPERALIG---IHRPGAFAEYVEVPAGSLHALPEGVDLRSAALA 143 Query: 434 EPLAVGIHACKRG 472 EPLA G+HA G Sbjct: 144 EPLANGVHAAGLG 156 >UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase, zinc-binding:Alcohol dehydrogenase GroES-like; n=2; Alphaproteobacteria|Rep: Alcohol dehydrogenase, zinc-binding:Alcohol dehydrogenase GroES-like - Caulobacter sp. K31 Length = 364 Score = 59.7 bits (138), Expect = 6e-08 Identities = 32/82 (39%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 P L + PIP+I D +LR++ GICGSD ++ G P+I GHE G++ Sbjct: 14 PRTLEMRDLPIPDIEADSAILRIEACGICGSDYEQFE----GVLKTPMPVIPGHEPVGII 69 Query: 198 AKIGSKVK---NLTVGDRVAIE 254 IG K + VGDRVA+E Sbjct: 70 EAIGDKAARRWGVDVGDRVAVE 91 Score = 32.7 bits (71), Expect = 8.2 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP-L 442 C C+ C GRYHLC D + P+ N+ + A + + P+ + + L P L Sbjct: 96 CHSCDTCLGGRYHLCADRQIYSYIPL-SNMPGLWGAYAQYMYLAPNTIVHKMDKTLPPEL 154 Query: 443 AV 448 AV Sbjct: 155 AV 156 >UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=18; Bacteria|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Psychrobacter sp. PRwf-1 Length = 354 Score = 59.7 bits (138), Expect = 6e-08 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 9/94 (9%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQ-----CGHF--VLEE 161 A Y D+R+ P P + V +++ GICG+D+H + +G CGH + E Sbjct: 4 ARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGE 63 Query: 162 --PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEP 257 P+ MGHE SGVV +G V ++ +G V +EP Sbjct: 64 SAPVTMGHEFSGVVYAVGEGVNDIEIGQHVVVEP 97 Score = 46.8 bits (106), Expect = 5e-04 Identities = 28/83 (33%), Positives = 38/83 (45%) Frame = +2 Query: 299 YHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGV 478 YHL DM F G L + + + + +++ AL+EPLAVG HA R G Sbjct: 112 YHLSKDMNFIGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLAVGYHAFIRSGA 171 Query: 479 SAGHVVLVLGRDPSASLPCSQLK 547 G + LV G P L + LK Sbjct: 172 QKGDIALVGGGGPIGLLLSAVLK 194 >UniRef50_A1RCH0 Cluster: Putative alcohol dehydrogenase; n=2; Arthrobacter aurescens TC1|Rep: Putative alcohol dehydrogenase - Arthrobacter aurescens (strain TC1) Length = 371 Score = 59.7 bits (138), Expect = 6e-08 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P DLR V P + EVL+R G+C SD+HY G +E P I+GHE G Sbjct: 15 QPLDLRPVILDDP--LDHEVLVRTLAAGLCHSDLHYLD----GSLEIELPAILGHEVVGT 68 Query: 195 VAKIGSKVKNLTVGDRV--AIEPAC 263 V ++G+ V L +GDRV + PAC Sbjct: 69 VERVGAAVSGLKIGDRVVATVTPAC 93 >UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus oeni|Rep: Sorbitol dehydrogenase - Oenococcus oeni ATCC BAA-1163 Length = 358 Score = 59.7 bits (138), Expect = 6e-08 Identities = 29/92 (31%), Positives = 54/92 (58%), Gaps = 6/92 (6%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L + + + P+PEI++DE+L++++ G+CG+DV ++ + P+ +GHE Sbjct: 19 AVLTGTKKIEVKKLPVPEINDDEMLVKVEGCGVCGTDVFEYKSDPFNYI----PVNLGHE 74 Query: 183 ASGVVAKIGSKVKN------LTVGDRVAIEPA 260 +G + K+G VKN L +GD++ PA Sbjct: 75 GTGEIVKMGKNVKNDWTGKTLKIGDKIVCGPA 106 >UniRef50_Q9HJX2 Cluster: Alcohol dehydrogenase related protein; n=4; Thermoplasmatales|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 336 Score = 59.7 bits (138), Expect = 6e-08 Identities = 36/84 (42%), Positives = 48/84 (57%), Gaps = 2/84 (2%) Frame = +3 Query: 3 ALLYKPND-LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFV-LEEPMIMG 176 ALL K N L +V IPE E+EV+++ D G+C D+ G F ++ P+I G Sbjct: 4 ALLEKLNQPLSIVDREIPEPGENEVVIKQDYAGLCYRDI----LSATGFFPRIQLPIIPG 59 Query: 177 HEASGVVAKIGSKVKNLTVGDRVA 248 HE G V K GS+V+N VGD VA Sbjct: 60 HEIGGTVVKTGSEVRNFHVGDHVA 83 >UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17; Gammaproteobacteria|Rep: L-idonate 5-dehydrogenase - Escherichia coli (strain K12) Length = 343 Score = 59.7 bits (138), Expect = 6e-08 Identities = 27/55 (49%), Positives = 38/55 (69%) Frame = +3 Query: 96 GICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPA 260 GICGSD+HY+Q+G+ G+F+++ PM++GHE G V I S L G VAI P+ Sbjct: 38 GICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINPS 90 Score = 52.8 bits (121), Expect = 7e-06 Identities = 33/101 (32%), Positives = 42/101 (41%), Gaps = 4/101 (3%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGAL 430 PC +C++C + C DM F + P V G RY C P + A Sbjct: 92 PCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAF 151 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 EPLAV IHA + G G V + G P L S +K L Sbjct: 152 AEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTL 192 >UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=2; Streptomyces|Rep: Putative zinc-binding dehydrogenase - Streptomyces avermitilis Length = 329 Score = 59.3 bits (137), Expect = 8e-08 Identities = 27/76 (35%), Positives = 47/76 (61%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 + + P P EV++ + G+CG+D+H Q G F + P++ GHE +G V +G+ Sbjct: 14 VAEVPDPTPGPREVVVEVAACGLCGTDLHILQ----GEFAPKLPIVPGHEFAGEVVGLGT 69 Query: 213 KVKNLTVGDRVAIEPA 260 +V ++VGDRVA++P+ Sbjct: 70 QVTEVSVGDRVAVDPS 85 Score = 46.8 bits (106), Expect = 5e-04 Identities = 26/81 (32%), Positives = 35/81 (43%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C+TG +LC G RY C KLP+HV ++ AL+EPL+ Sbjct: 88 CYECRYCRTGHNNLCERWAAIGVTTA-GGAARYAVAPVANCVKLPEHVRTQDAALIEPLS 146 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 + G VLV G Sbjct: 147 CAVRGYDVLRSRLGAHVLVYG 167 >UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5; Pseudomonas|Rep: Benzyl alcohol dehydrogenase II - Pseudomonas putida Length = 348 Score = 59.3 bits (137), Expect = 8e-08 Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Frame = +3 Query: 18 PNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 P L + P E +VL++++ GICG+D+ ++ G+ ++ P I+GHE SGV Sbjct: 11 PGGLSVDDVAAPKEAHSTDVLVKVEAAGICGTDLLIYKWGEFAKR-MKLPTILGHEVSGV 69 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQ 293 + ++GS VK L G RV++E GT + R+ Sbjct: 70 IEQVGSDVKGLRPGMRVSLESHLPCGTCYTCRR 102 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/102 (25%), Positives = 43/102 (42%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 +PC C C+ G H+CP + G + C+ +P + + A++EP Sbjct: 92 LPCGTCYTCRRGWAHVCPKTRYPGVD-FDGGFASFVVVPESVCWPVPCGIPPLQAAMMEP 150 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 + +HA G +G VLV G P + + K L +K Sbjct: 151 FGLAVHASLEGSGVSGLNVLVSGCGPIGLMNIAAAKALGASK 192 >UniRef50_A0QZI7 Cluster: Aryl-alcohol dehydrogenase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Aryl-alcohol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 379 Score = 59.3 bits (137), Expect = 8e-08 Identities = 27/62 (43%), Positives = 41/62 (66%) Frame = +3 Query: 66 DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRV 245 DE+L+R+D VGIC +D + Q G + PM+ GHE +G+V ++GS V++L GDRV Sbjct: 41 DEILVRVDAVGICHADT----QAQTGALPVPAPMVAGHEGTGIVEEVGSDVQHLKCGDRV 96 Query: 246 AI 251 + Sbjct: 97 IL 98 >UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol dehydrogenase GroES-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 341 Score = 58.8 bits (136), Expect = 1e-07 Identities = 28/77 (36%), Positives = 43/77 (55%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P + + + P P EVLLR+ G+CGSDVH + + G + P+ +GHE +G Sbjct: 10 RPGEAGVAELPAPRPGPGEVLLRVAACGVCGSDVHAF-RSDPGFEWISTPVTLGHEFAGT 68 Query: 195 VAKIGSKVKNLTVGDRV 245 V +G V+ + GDRV Sbjct: 69 VEALGPGVERVAPGDRV 85 Score = 41.9 bits (94), Expect = 0.013 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 1/97 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C CE C G LCPD + G + Y +P+ + + AL EPL+ Sbjct: 93 CGRCELCLAGLTQLCPDRVAVGLSR-DGGMAEYAVMPEGHLVSVPEGLDLTLAALCEPLS 151 Query: 446 VGIHAC-KRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 V + A R G++ V+V G P L C+ + L Sbjct: 152 VAVRAVDARAGIAPEGKVVVSGPGPIGIL-CAMVARL 187 >UniRef50_Q0SAT0 Cluster: Zn-containing alcohol dehdyrogenase; n=26; cellular organisms|Rep: Zn-containing alcohol dehdyrogenase - Rhodococcus sp. (strain RHA1) Length = 446 Score = 58.8 bits (136), Expect = 1e-07 Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%) Frame = +3 Query: 3 ALLYK-PNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 176 AL+Y P ++ + P I + +VL+++ ICGSD+H ++ G LE M++G Sbjct: 70 ALVYDGPREVHVKDMPDARIEQPTDVLVKITSTNICGSDLHMYE----GRTDLEPGMVLG 125 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT*SSAPR 335 HE G+VA++G+ V ++ GDRV + G + + T + LT P+ Sbjct: 126 HENLGIVAEVGNAVVKVSPGDRVCLPFNIGCGFCRNCEEGLTAFCLTVHPDPK 178 >UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Arthrobacter sp. (strain FB24) Length = 355 Score = 58.8 bits (136), Expect = 1e-07 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 1/86 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPE-ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A+L NDL P P+ + E+ VL+R+ VG+CGSDV + G+ H+ P+++GH Sbjct: 4 AILNGLNDLEYADIPEPQPVGENPVLVRVGAVGVCGSDVLRYGHGKAYHY----PLVLGH 59 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 E S +V + +L+ GDR A+ P Sbjct: 60 EFSAIVEEAPDS-PHLSAGDRAAVFP 84 Score = 33.5 bits (73), Expect = 4.7 Identities = 15/55 (27%), Positives = 28/55 (50%) Frame = +2 Query: 389 FKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 F++P+ + + A++EP V +HA + + LV+G P +L L+ L Sbjct: 128 FRVPNDMPLTHAAMVEPAGVALHAMLKVQIPTHTTALVIGAGPIGALAAQWLRIL 182 >UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol dehydrogenase; n=4; Endopterygota|Rep: Putative zinc-containing alcohol dehydrogenase - Lysiphlebus testaceipes (Greenbugs aphid parastoid) Length = 340 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 2/80 (2%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--MIMGHEASGVV 197 +L LV IP+ DE+L+R+ GICG+D+H G F + + +GHE SGV+ Sbjct: 12 NLSLVHGEIPKPGPDEILVRVHYSGICGTDLHILD----GSFPAKSDGNLTLGHEFSGVI 67 Query: 198 AKIGSKVKNLTVGDRVAIEP 257 IGS VK +G VAI+P Sbjct: 68 EDIGSIVKGFKIGQSVAIDP 87 Score = 39.1 bits (87), Expect = 0.095 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 C C+FC TG+YH C + T + G + + LP V M + AL EP Sbjct: 91 CNKCDFCHTGKYHFCDNGGINNTIGIFRDGGWSTHAVVPESQVYLLPSGVEMPQAALAEP 150 Query: 440 LAVGIHACK-RGGVSAGHVVLVLG 508 L+ H V+ G +LV+G Sbjct: 151 LSCLAHGWDIINPVTVGTNILVIG 174 >UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases; n=1; Brevibacterium linens BL2|Rep: COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases - Brevibacterium linens BL2 Length = 328 Score = 58.4 bits (135), Expect = 1e-07 Identities = 30/103 (29%), Positives = 42/103 (40%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C CE+C+ G C + G L H ++FC +L H+++E EP Sbjct: 89 ITCGRCEYCRRGMTSACTSRLSAGVLTQPGFLAEVVDHPSEFCHRLDAHMSLERAVCAEP 148 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTKY 568 LAV A +R + VLVLG L L H Y Sbjct: 149 LAVAASAIRRTDLQGSETVLVLGAGAQGLLSILTLVAQGHHPY 191 Score = 48.8 bits (111), Expect = 1e-04 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Frame = +3 Query: 18 PNDLRLVQTPIPE--ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEAS 188 P + +V +P+ + ++ +RM VGICG+D Q G + P +GHE Sbjct: 9 PGRVEIVDRSLPQGLVGRGDLRIRMLAVGICGTD----QTLATGRRTPPQLPWRLGHEGI 64 Query: 189 GVVAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTT 305 G +A++G VGDRVA+EP G R+ T+ Sbjct: 65 GEIAEVGPGACGFAVGDRVALEPNITCGRCEYCRRGMTS 103 >UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable Zn-containing alcohol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 353 Score = 58.4 bits (135), Expect = 1e-07 Identities = 33/98 (33%), Positives = 52/98 (53%), Gaps = 6/98 (6%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG----QCGHFVLEE--PMI 170 LY+ +D RL + P PE+ V +++ GICGSD+ ++ + +++E P Sbjct: 6 LYREHDARLEEVPEPELRPGAVKVKVAWAGICGSDLSLFETAPVPLDYSNPIMQETGPHT 65 Query: 171 MGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVGTASS 284 +GHE SG V ++ V + VGD VA+ P GT S Sbjct: 66 LGHEFSGYVTEVAEGVTTVQVGDLVAVRPNFADGTCPS 103 >UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol dehydrogenase-like protein HI0053; n=18; Gammaproteobacteria|Rep: Uncharacterized zinc-type alcohol dehydrogenase-like protein HI0053 - Haemophilus influenzae Length = 342 Score = 58.4 bits (135), Expect = 1e-07 Identities = 31/84 (36%), Positives = 56/84 (66%), Gaps = 1/84 (1%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 L KPN++ + + P PE S+++VL++++ +GICGSD+ + +G + ++ P I+GHE Sbjct: 10 LEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAY-RGT--NPLVTYPRILGHEIV 66 Query: 189 GVVAKIGSKVKN-LTVGDRVAIEP 257 G V + G + + + VGDRV ++P Sbjct: 67 GRVIESGIGMSDGVRVGDRVIVDP 90 Score = 47.2 bits (107), Expect = 4e-04 Identities = 22/83 (26%), Positives = 40/83 (48%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C C C GR + C + + G + +H A K+PD++ + + L EP Sbjct: 92 VCCGQCYPCSIGRTNCCESLKVIGVH-IDGGMQEVIRHPAHLLTKVPDNLPIHQLPLAEP 150 Query: 440 LAVGIHACKRGGVSAGHVVLVLG 508 L + +HA R + +G ++++G Sbjct: 151 LTIALHALHRTTLKSGEHIVIIG 173 >UniRef50_P14940 Cluster: Alcohol dehydrogenase; n=31; cellular organisms|Rep: Alcohol dehydrogenase - Ralstonia eutropha (Alcaligenes eutrophus) Length = 366 Score = 58.4 bits (135), Expect = 1e-07 Identities = 28/87 (32%), Positives = 46/87 (52%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ +P + L PIP+I ++ L+R+ ICG+DVH + G + + + + +GHE Sbjct: 8 AVFVEPGRIELADKPIPDIGPNDALVRITTTTICGTDVHILK----GEYPVAKGLTVGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPAC 263 G++ K+GS V G RV C Sbjct: 64 PVGIIEKLGSAVTGYREGQRVIAGAIC 90 >UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=2; Bordetella|Rep: Putative Zinc-binding dehydrogenase - Bordetella parapertussis Length = 360 Score = 58.0 bits (134), Expect = 2e-07 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = +3 Query: 18 PNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 P L VQ P+PE+ + DE L+R++ GICG+D ++ G GH +I GHE G Sbjct: 11 PRRLEYVQLPLPEVLAPDEALVRVEGCGICGTDYERYE-GSLGHV---PELIPGHEPVGR 66 Query: 195 VAKIGSKV---KNLTVGDRVAIEPACRVGTAS 281 + +IG L GDRVA++P G S Sbjct: 67 IERIGDSAAQRMQLKEGDRVAVQPHYGCGVCS 98 Score = 34.3 bits (75), Expect = 2.7 Identities = 22/89 (24%), Positives = 33/89 (37%), Gaps = 8/89 (8%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVH------GNLVRYYKHAAD-FCFKLPDHVTMEEG 424 C C +C G + LC I P+ G + + K+PD + +E+ Sbjct: 94 CGVCSYCVEGMFQLCARKINLGLSPLSEGCGLWGGFAEHMMLKGNAIVHKMPDSLPIEDA 153 Query: 425 ALLEPLAVGIH-ACKRGGVSAGHVVLVLG 508 + PL G A G G VL+ G Sbjct: 154 VMFNPLGAGFEWAITSAGTRVGDDVLIFG 182 >UniRef50_Q1GKP3 Cluster: Alcohol dehydrogenase GroES-like protein; n=31; Bacteria|Rep: Alcohol dehydrogenase GroES-like protein - Silicibacter sp. (strain TM1040) Length = 346 Score = 58.0 bits (134), Expect = 2e-07 Identities = 29/74 (39%), Positives = 42/74 (56%) Frame = +3 Query: 30 RLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIG 209 +LV P D V+++++ G+C SD H W G VL P + GHE +GV+ +G Sbjct: 14 KLVTVEDPTPDPDGVVIKVEATGLCRSDWHGWM-GHDSDIVL--PHVPGHEFAGVIVALG 70 Query: 210 SKVKNLTVGDRVAI 251 V+N TVGDRV + Sbjct: 71 KNVRNWTVGDRVTV 84 >UniRef50_A0NJ16 Cluster: L-iditol 2-dehydrogenase; n=5; Bacteria|Rep: L-iditol 2-dehydrogenase - Oenococcus oeni ATCC BAA-1163 Length = 342 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/69 (40%), Positives = 41/69 (59%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 230 P++ +VL+++ GICGSD Y G P+ GHEA+G+VA IGS V +++ Sbjct: 23 PQVGRQDVLIKIKANGICGSDTFYTSIGGIPPRQGHTPL--GHEAAGIVADIGSNVDDVS 80 Query: 231 VGDRVAIEP 257 +GD V I P Sbjct: 81 IGDHVVINP 89 >UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1; Bacillus licheniformis ATCC 14580|Rep: Putative uncharacterized protein - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 337 Score = 57.6 bits (133), Expect = 3e-07 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASG 191 KP ++ +PE+ + E L+R+ +GICG+D H + CG P ++GHE SG Sbjct: 8 KPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAY----CGRQPFFSYPRVLGHELSG 63 Query: 192 VVAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 + I + L GD+V+I P G + R Sbjct: 64 EIVSIDNSGGTLKPGDQVSIIPYLECGACIACR 96 Score = 48.8 bits (111), Expect = 1e-04 Identities = 26/84 (30%), Positives = 41/84 (48%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C+ GR + C ++ G + Y AD K + +T+ E A++E L+ Sbjct: 89 CGACIACRNGRPNCCVNLNVLGVH-TDGGMREYINVPADHLLKT-EGLTLSEAAVVECLS 146 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 +G HA +R + G VLV+G P Sbjct: 147 IGAHAAERANIKKGETVLVVGAGP 170 >UniRef50_A7BDX1 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 352 Score = 57.6 bits (133), Expect = 3e-07 Identities = 35/104 (33%), Positives = 52/104 (50%) Frame = +3 Query: 36 VQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 215 ++ I E E E+ + GIC SD+H +G+ G + P++ GHE G VAK+G Sbjct: 19 LEIDIREPGEGEIYFDVAYAGICHSDIHA-ARGEWGP--VSYPLVPGHEFVGTVAKVGPG 75 Query: 216 VKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT*SSAPRPQYT 347 V VGDRV + C VG+ S ++ Y +S P +T Sbjct: 76 VTTFKVGDRVGV--GCMVGSCGSCEMCESDYEQWCTSTPGTLWT 117 >UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Desulfotomaculum reducens MI-1|Rep: Alcohol dehydrogenase GroES domain protein - Desulfotomaculum reducens MI-1 Length = 345 Score = 57.6 bits (133), Expect = 3e-07 Identities = 32/89 (35%), Positives = 48/89 (53%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 LL + N+L L IP EVL+++ GIC +D+ ++ GH L P I+GHE Sbjct: 5 LLEQANNLVLKTIEIPRCKAGEVLVKVAACGICRTDMKSYR---LGHRDLHLPRILGHEI 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 +G V +IG+ V + G+RV + P G Sbjct: 62 AGTVVEIGAGVTEVHCGERVQVSPGLPCG 90 Score = 49.2 bits (112), Expect = 9e-05 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA-----ADFCFKLPDHVTMEE 421 G+PC C C TG HLCP++ G Y A KLPDH +E Sbjct: 86 GLPCGVCPNCLTGLNHLCPNIEIMGFH-YDGGFAEYVLIPSKGVKAKVLNKLPDHFPIEL 144 Query: 422 GALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 AL EPLA I+ + + +G +++ G P Sbjct: 145 AALTEPLACCINIQESMDIGSGDTIIIFGAGP 176 >UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain protein; n=10; Proteobacteria|Rep: Alcohol dehydrogenase GroES domain protein - Escherichia coli B Length = 336 Score = 57.6 bits (133), Expect = 3e-07 Identities = 30/74 (40%), Positives = 43/74 (58%) Frame = +3 Query: 36 VQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 215 V+ P E+ EV + GICGSD+H KG GH + P++ GHE + V ++GS Sbjct: 20 VEVPHQELKPHEVRIAPVFYGICGSDLHVL-KG--GHPFAKPPVVPGHEIAARVTEVGSD 76 Query: 216 VKNLTVGDRVAIEP 257 VKN+ GD V ++P Sbjct: 77 VKNVQPGDHVVVDP 90 >UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogenase; n=8; Saccharomycetales|Rep: Potential secondary alcohol dehydrogenase - Candida albicans (Yeast) Length = 359 Score = 57.6 bits (133), Expect = 3e-07 Identities = 28/69 (40%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Frame = +3 Query: 45 PIPEISEDEVLLRMDCVGICGSDVHYWQKG-QCGHFVLEEPMIMGHEASGVVAKIGSKVK 221 P+ + ++LL++D VG+C SD+H +G CG + +MGHE +G VA++G +V Sbjct: 48 PVNKPGAGQLLLKVDAVGLCHSDLHVLYEGLDCG-----DNYVMGHEIAGTVAELGEEVS 102 Query: 222 NLTVGDRVA 248 VGDRVA Sbjct: 103 EFAVGDRVA 111 >UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4; Sulfolobaceae|Rep: Sorbitol dehydrogenase - Sulfolobus solfataricus Length = 345 Score = 57.6 bits (133), Expect = 3e-07 Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 5/101 (4%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA-----DFCFKLPDHVTMEEG 424 VPC C +CK G +CP + T G Y++ A KLPD+V+ EEG Sbjct: 89 VPCYECYYCKKGSPTMCP--YYRKTNLDPGGFSEYFRVPAWNVARGGVLKLPDNVSFEEG 146 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 A +EPLA I A KR + G V ++G P L K Sbjct: 147 AFIEPLATVIRAQKRVAIDNGDTVFIVGIGPMGLLHAMMAK 187 Score = 49.2 bits (112), Expect = 9e-05 Identities = 24/69 (34%), Positives = 43/69 (62%) Frame = +3 Query: 39 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 218 + P+P++ + +VL++M G+CG+D+ + CG + +P I+GHE +G++ + S V Sbjct: 22 ELPLPKLQQGDVLVKMKACGLCGTDI----EKICGQYTASQP-ILGHEPTGIIQE--STV 74 Query: 219 KNLTVGDRV 245 L GDRV Sbjct: 75 DWLKPGDRV 83 >UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol dehydrogenase-like protein yjjN; n=29; Gammaproteobacteria|Rep: Uncharacterized zinc-type alcohol dehydrogenase-like protein yjjN - Escherichia coli (strain K12) Length = 337 Score = 57.6 bits (133), Expect = 3e-07 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P +L Q IP ++E L+++ VGICG+D+H W Q P ++GHE G Sbjct: 8 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQP---FFSYPRVLGHEICGE 64 Query: 195 VAKIGSKVKNLTVGDRVAIEP--ACR 266 + +G + +L G +VA+ P AC+ Sbjct: 65 IVGLGKNIADLKNGQQVAVIPYVACQ 90 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLP-DHVTMEEGALLE 436 V C+ C CK+GR + C + I G Y + LP D + + AL+E Sbjct: 87 VACQQCPACKSGRTNCC-EKISVIGVHQDGGFSEYL--SVPVANILPADGIDPQAAALIE 143 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 P A+ HA +R ++ G VLV+G P Sbjct: 144 PFAISAHAVRRAAIAPGEQVLVVGAGP 170 >UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14; Bacillales|Rep: Sorbitol dehydrogenase - Bacillus halodurans Length = 343 Score = 57.6 bits (133), Expect = 3e-07 Identities = 25/72 (34%), Positives = 42/72 (58%) Frame = +3 Query: 39 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 218 + P P + +V +++ G+CGSD+H ++ GH+ + P+ +GHE SG + ++G V Sbjct: 18 EKPEPTPGKHQVKIKVKYTGVCGSDIHTYE----GHYPVAAPVTLGHEFSGEIVELGEGV 73 Query: 219 KNLTVGDRVAIE 254 VGDRV E Sbjct: 74 TGFNVGDRVTSE 85 Score = 42.7 bits (96), Expect = 0.008 Identities = 26/94 (27%), Positives = 38/94 (40%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C +G Y+LC G+ +Y + LP V A+ EPLA Sbjct: 91 CGKCSYCTSGDYNLCSHRKGLGNQQ-DGSFAKYVIARQESLHHLPAGVDDRSAAMTEPLA 149 Query: 446 VGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 HA + ++ G +V+V G P L K Sbjct: 150 CTHHAIAKTSINKGDLVVVTGPGPIGLLAAQVAK 183 >UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing; n=36; Bacteria|Rep: Alcohol dehydrogenase, zinc-containing - Deinococcus radiodurans Length = 431 Score = 57.2 bits (132), Expect = 3e-07 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = +3 Query: 24 DLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 D+RL P P+I + + ++R+ ICG+D+H+ +G V I+GHE G+V Sbjct: 37 DIRLDDVPEPKIEAPTDAIVRLTASAICGTDLHFI-RGTMSDMV--PGTILGHEGVGIVE 93 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTT 305 +G +V+N GDRV I + G R+ +T+ Sbjct: 94 AVGPEVRNFVPGDRVVIPSSASCGYCPPCREGNTS 128 >UniRef50_Q5YU97 Cluster: Putative dehydrogenase; n=1; Nocardia farcinica|Rep: Putative dehydrogenase - Nocardia farcinica Length = 340 Score = 57.2 bits (132), Expect = 3e-07 Identities = 30/83 (36%), Positives = 45/83 (54%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 ++ P + L +PE + ++ + GICGSD+ Y + G EPM +GHE S Sbjct: 10 VHGPGTIGLDLVELPECGPRDAVVELRACGICGSDLGYIRLGGVAG-PGSEPMPLGHEIS 68 Query: 189 GVVAKIGSKVKNLTVGDRVAIEP 257 GVV+ IG++V L G RV + P Sbjct: 69 GVVSAIGAEVDGLRPGQRVVVHP 91 Score = 39.9 bits (89), Expect = 0.054 Identities = 22/63 (34%), Positives = 30/63 (47%) Frame = +2 Query: 374 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPL 553 A D F +PD + + AL EP+AVG+HA + +S V V G P + L Sbjct: 119 AGDRLFPIPDDMPFDVAALAEPVAVGMHAVDQADLSPTDPVAVFGCGPIGLAAIATLADR 178 Query: 554 EHT 562 HT Sbjct: 179 GHT 181 >UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protein; n=1; Chromohalobacter salexigens DSM 3043|Rep: Alcohol dehydrogenase GroES-like protein - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 349 Score = 57.2 bits (132), Expect = 3e-07 Identities = 31/96 (32%), Positives = 47/96 (48%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +P + L P P+ + E +LR+ VGICG+D+H + G +F P ++GHE SG Sbjct: 8 QPRHMELRDVPEPQCAPGEAMLRIRRVGICGTDIHAY-GGNQPYFTY--PRVLGHELSGD 64 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDT 302 + +G V VG + P G + RQ T Sbjct: 65 IVGVGEGVDESLVGHSAYVIPYLHCGECRACRQGKT 100 >UniRef50_A6WA66 Cluster: Alcohol dehydrogenase zinc-binding domain protein; n=2; Actinomycetales|Rep: Alcohol dehydrogenase zinc-binding domain protein - Kineococcus radiotolerans SRS30216 Length = 381 Score = 57.2 bits (132), Expect = 3e-07 Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Frame = +3 Query: 33 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 212 L + P+P E L+R+ G+C SD+H + G P ++GHE SG + ++G Sbjct: 26 LERVPVPAPRAGEALIRVAACGVCHSDLHVLK----GEIAFPRPAVLGHEISGTIVQLGD 81 Query: 213 KVKNLTVGDRVA---IEPACRVGTASSVRQD 296 V+NL VGD V I P R R D Sbjct: 82 GVENLRVGDAVVGGFIMPCTRCDECQRGRDD 112 >UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanicola batsensis HTCC2597|Rep: Threonine 3-dehydrogenase - Oceanicola batsensis HTCC2597 Length = 349 Score = 57.2 bits (132), Expect = 3e-07 Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Frame = +3 Query: 27 LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEE-PMIMGHEASGV 194 L L P P E EV +R++ VGICGSD+H W G F+L P+ +GHE +G+ Sbjct: 13 LSLDDCPAPGAPEAGEVTVRVEAVGICGSDLHVADWSGGY--DFMLPHLPLTLGHEFAGI 70 Query: 195 VAKIGSKVKNLTVGDRVAIEPA 260 + G V +T GDRV I P+ Sbjct: 71 IEATGPGVARVTPGDRVTIWPS 92 Score = 47.6 bits (108), Expect = 3e-04 Identities = 33/84 (39%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 PC C C GR C + AT ++ G A F +PD ++ E AL E Sbjct: 94 PCDTCPECTAGRRRNCRNK---ATLGLYRDGAFAPLVTARAQGAFTIPDALSFEIAALTE 150 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PL VG A K G VS G VLVLG Sbjct: 151 PLCVGRRAVKTGEVSPGDRVLVLG 174 >UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like protein YAL061W; n=8; Saccharomycetales|Rep: Zinc-type alcohol dehydrogenase-like protein YAL061W - Saccharomyces cerevisiae (Baker's yeast) Length = 417 Score = 57.2 bits (132), Expect = 3e-07 Identities = 31/81 (38%), Positives = 49/81 (60%), Gaps = 11/81 (13%) Frame = +3 Query: 57 ISEDEVLLRMDCVGICGSDVHYWQKG-----QCGHF--VLEEPM--IMGHEASGVVAKIG 209 ++ DE+++ ++ GICG+D+H + G + GH + P+ MGHE +G V ++G Sbjct: 24 VAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTHEISHNPLPQAMGHEMAGTVLEVG 83 Query: 210 SKVKNLTVGDRVAIEP--ACR 266 VKNL VGD+V +EP CR Sbjct: 84 PGVKNLKVGDKVVVEPTGTCR 104 Score = 55.6 bits (128), Expect = 1e-06 Identities = 26/82 (31%), Positives = 39/82 (47%) Frame = +2 Query: 272 YCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVG 451 +C CK G Y++C + C G C+K+PD V ++ AL++PLAV Sbjct: 119 WCAACKKGYYNICSYLGLCGAGVQSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVC 178 Query: 452 IHACKRGGVSAGHVVLVLGRDP 517 HA + AG L++G P Sbjct: 179 WHAIRVCEFKAGSTALIIGAGP 200 >UniRef50_P07246 Cluster: Alcohol dehydrogenase III, mitochondrial precursor; n=79; Eukaryota|Rep: Alcohol dehydrogenase III, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 375 Score = 57.2 bits (132), Expect = 3e-07 Identities = 26/70 (37%), Positives = 41/70 (58%) Frame = +3 Query: 45 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 224 P+PE +E+L+ + G+C +D+H W ++ P++ GHE +GVV K+GS VK Sbjct: 52 PVPEPKPNEILINVKYSGVCHTDLHAWHGDW--PLPVKLPLVGGHEGAGVVVKLGSNVKG 109 Query: 225 LTVGDRVAIE 254 VGD I+ Sbjct: 110 WKVGDLAGIK 119 >UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyces coelicolor|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 344 Score = 56.8 bits (131), Expect = 4e-07 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 + C+ C C+ G H+C + +F P G ++ ++P V + AL E Sbjct: 89 ISCKDCRACREGHSHVCARLGLFGIDAP--GGAAQFVALPTSTLHQVPSRVEPTQAALTE 146 Query: 437 PLAVGIHACKRGGVSAGHVVLVLGRDP 517 PLAV +HA R G+ AG VV V G P Sbjct: 147 PLAVAVHAVSRSGMEAGDVVAVFGAGP 173 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/59 (38%), Positives = 36/59 (61%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 ND+R+ + P+PE+ L+R+ C GICG+D+ G+ H + +I+GHE SG V Sbjct: 14 NDVRVEEVPMPEVPPGWALVRVACTGICGTDLGI-VHGK--HPRARQGLILGHEISGWV 69 >UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Rep: AGR_L_281p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 397 Score = 56.8 bits (131), Expect = 4e-07 Identities = 26/46 (56%), Positives = 33/46 (71%) Frame = +2 Query: 392 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 K+PD +T EE AL+EP AV ++AC RGGV+AG+ VLV G P L Sbjct: 183 KIPDEMTDEEAALVEPSAVAVYACDRGGVTAGNSVLVTGAGPIGML 228 Score = 53.6 bits (123), Expect = 4e-06 Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 10/88 (11%) Frame = +3 Query: 24 DLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP---------MIM 173 DLR+ P+ +VL+R VGICG+D+H + G F+ EP I+ Sbjct: 51 DLRIEDIAEPKRPGPGQVLVRNRFVGICGTDLHEYSYGPI--FIPTEPHPFTGAHGPQIL 108 Query: 174 GHEASGVVAKIGSKVKNLTVGDRVAIEP 257 GHE GVV IG V ++ VGDRV+I+P Sbjct: 109 GHEFGGVVEAIGDGVTSVNVGDRVSIQP 136 >UniRef50_Q0SDC0 Cluster: Zn-binding alcohol dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Zn-binding alcohol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 367 Score = 56.8 bits (131), Expect = 4e-07 Identities = 33/93 (35%), Positives = 54/93 (58%), Gaps = 2/93 (2%) Frame = +3 Query: 3 ALLYKPND-LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 AL P++ L +V + ++EDE+ +R+ VGIC +D+ + G L P ++GH Sbjct: 7 ALFEAPDEKLTVVDVQVGPLAEDEIRIRVAGVGICHTDLTALRGG----VPLPLPAVLGH 62 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIE-PACRVGT 275 EASG+V ++G++V L GD V + +CR T Sbjct: 63 EASGIVEEVGAEVTALVPGDHVVVSFDSCRTCT 95 >UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=1; Pelotomaculum thermopropionicum SI|Rep: Zn-dependent alcohol dehydrogenases - Pelotomaculum thermopropionicum SI Length = 372 Score = 56.8 bits (131), Expect = 4e-07 Identities = 32/92 (34%), Positives = 53/92 (57%), Gaps = 2/92 (2%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 179 A+++ D+R+ P+PE EVL+++ GIC +D+ K G + E+ P I+GH Sbjct: 27 AVVHGKGDIRIEPVPVPETGYGEVLVKVRASGICATDI----KTLLGQGLPEKLPAILGH 82 Query: 180 EASGVVAKIGSKVK-NLTVGDRVAIEPACRVG 272 E +G V ++G V+ +L+ G RVA+ P G Sbjct: 83 EVAGTVERVGPGVRGDLSPGKRVAVYPIAVCG 114 Score = 48.8 bits (111), Expect = 1e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFC-----FKLPDHVTMEEGAL 430 C C FCK GR++LC A + G +Y + + +LP+H++ E+ A+ Sbjct: 113 CGECFFCKRGRHNLCLREYGLAHG-IDGGFAQYVRIPREIVAIGGLVELPEHLSYEQAAM 171 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDPSASL 529 EPL+ + A + G + G +LV+G P L Sbjct: 172 AEPLSCCLAAARAGKLEEGDTMLVVGAGPMGLL 204 >UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 341 Score = 56.8 bits (131), Expect = 4e-07 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = +3 Query: 3 ALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A+LY+ P + P P+ + EV +R+ VG+CG+D+H G F P+I GH Sbjct: 3 AVLYEAPKTWSVTDVPTPQPGKGEVRIRVAQVGVCGTDLHIHD----GEFGAVFPLIPGH 58 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 E GVV +G V +G++V + P Sbjct: 59 ELVGVVDAVGEGVTRFGIGEQVTVNP 84 >UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1; Serratia proteamaculans 568|Rep: Alcohol dehydrogenase GroES-like - Serratia proteamaculans 568 Length = 341 Score = 56.8 bits (131), Expect = 4e-07 Identities = 31/97 (31%), Positives = 48/97 (49%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 KP L + PIP EVLL+M +G+CGSD+H + Q +++ P ++GHE + Sbjct: 12 KPGQLSQQRRPIPLPGTGEVLLKMCALGVCGSDIHAFHGRQP---MMQYPAVLGHEINAE 68 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTT 305 V G G +V + P G ++ R+ TT Sbjct: 69 VVACGQDAALYQPGQQVVVIPYRHCGRCAACRRGRTT 105 >UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 386 Score = 56.8 bits (131), Expect = 4e-07 Identities = 29/82 (35%), Positives = 44/82 (53%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L + + + P+P + D VL+++ GICGSD+H + G G +MGHEA Sbjct: 27 VLVEKRRISIEPIPMPILQPDGVLVKVIANGICGSDMHVYLSGGIGGRGAYGRTVMGHEA 86 Query: 186 SGVVAKIGSKVKNLTVGDRVAI 251 +G V +G V GDRVA+ Sbjct: 87 AGEVIAVGEHVTTHKPGDRVAV 108 Score = 37.1 bits (82), Expect = 0.38 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Frame = +2 Query: 317 MIFCATPPVHG--NLVR--YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSA 484 ++ CA + G +L R ++ AD +P+ V+ EE ++PLA+GI KR + A Sbjct: 111 VLMCAIAVLRGTMDLSRGMFFALPADMAPHIPETVSWEEAGSIQPLAIGIQIGKRADLRA 170 Query: 485 GHVVLVLGRDP 517 V + G P Sbjct: 171 HQTVAIFGCGP 181 >UniRef50_A6S0I2 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 385 Score = 56.8 bits (131), Expect = 4e-07 Identities = 28/66 (42%), Positives = 43/66 (65%) Frame = +3 Query: 54 EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTV 233 +I + EVL+++ GIC +D+++ Q G F P I+GHE +G+++K GSKV NL V Sbjct: 25 DIRDTEVLVQIVATGICHTDINFSQHDIDGMF----PAILGHEGAGIISKAGSKVTNLEV 80 Query: 234 GDRVAI 251 GD V + Sbjct: 81 GDCVIL 86 >UniRef50_Q96XE0 Cluster: NAD-dependent alcohol dehydrogenase; n=5; Thermoprotei|Rep: NAD-dependent alcohol dehydrogenase - Sulfolobus tokodaii Length = 347 Score = 56.8 bits (131), Expect = 4e-07 Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 6/83 (7%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE------PMIMGHEAS 188 L+L PIP+ +VL++++ G+C SDVH ++G+ G+ + E P+ +GHE + Sbjct: 13 LKLEDIPIPKPKGSQVLIKIEAAGVCHSDVH-MRQGRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 189 GVVAKIGSKVKNLTVGDRVAIEP 257 G + ++G +V + GD VA+ P Sbjct: 72 GRIEEVGDEVVGYSKGDLVAVNP 94 >UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n=1; Apis mellifera|Rep: PREDICTED: similar to R04B5.5 - Apis mellifera Length = 338 Score = 56.4 bits (130), Expect = 6e-07 Identities = 31/83 (37%), Positives = 48/83 (57%), Gaps = 2/83 (2%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--MIMGHEAS 188 K + L L + +P ++V +R+ GICG+D+H + G F ++ + +GHE + Sbjct: 9 KNHTLALRRADVPNPGPNDVRIRIAYSGICGTDLHILE----GSFPCKKDGFLTLGHEFA 64 Query: 189 GVVAKIGSKVKNLTVGDRVAIEP 257 G V IGS VKN VG RVA++P Sbjct: 65 GTVDAIGSSVKNFKVGQRVAVDP 87 Score = 37.1 bits (82), Expect = 0.38 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 C C +C G Y C +T ++ G + + +PD V + + L+EP Sbjct: 91 CNTCNYCHDGSYQHCSAGGINSTIGIYKDGGFSTHAIVPESQVYLIPDDVELHQAVLVEP 150 Query: 440 LAVGIHACKR-GGVSAGHVVLVLG 508 L+ H K+ V+ G VLV+G Sbjct: 151 LSCLAHGWKKLNSVNVGSNVLVIG 174 >UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep: Lmo2663 protein - Listeria monocytogenes Length = 343 Score = 56.4 bits (130), Expect = 6e-07 Identities = 29/78 (37%), Positives = 47/78 (60%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 + + L P++ D+V +++ GICGSD+H + KG+ + P+ +GHE SGVV Sbjct: 12 DQMELKDVEEPQVYGDKVKIKVAFTGICGSDIHTF-KGEYKNPTT--PVTLGHEFSGVVV 68 Query: 201 KIGSKVKNLTVGDRVAIE 254 ++G V ++ VGDRV E Sbjct: 69 EVGPDVTSIKVGDRVTSE 86 Score = 45.2 bits (102), Expect = 0.001 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +CK Y+LC + T +G+ + + C L + +++E AL EPLA Sbjct: 92 CGECIYCKEHDYNLCSNRRGIGTQ-ANGSFAEFVLSREESCHVLDERISLEAAALTEPLA 150 Query: 446 VGIH-ACKRGGVSAGHVVLVLGRDPSASLPCSQLK 547 +H A ++ + VLV G P L +K Sbjct: 151 CCVHSALEKTTIRPDDTVLVFGPGPIGLLLAQVVK 185 >UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3; Actinomycetales|Rep: Zinc-type alcohol dehydrogenase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 357 Score = 56.4 bits (130), Expect = 6e-07 Identities = 33/102 (32%), Positives = 51/102 (50%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 L V P ++ D V+L M+ ICGSD+H KG ++ ++GHE G + ++ Sbjct: 17 LDTVDDPTIKLGTD-VILEMETTTICGSDLHIL-KGDVA--AVKPGTVLGHEGIGKIVEV 72 Query: 207 GSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT*SSAP 332 G VK+ +VGDRV + P G R ++ + L S P Sbjct: 73 GKDVKSHSVGDRVIVSPMSSCGVCRFCRANNNGHCLGDSEGP 114 >UniRef50_Q0S5T4 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Alcohol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 370 Score = 56.4 bits (130), Expect = 6e-07 Identities = 33/87 (37%), Positives = 51/87 (58%), Gaps = 2/87 (2%) Frame = +3 Query: 9 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 188 L +P + +Q PE +EV + + VG+C SD+HY G G + P+++GHE + Sbjct: 18 LNEPLEFTEIQVDDPE--PNEVRVAVSNVGLCHSDLHY-MTGTVG---ADLPVVVGHEVA 71 Query: 189 GVVAKIGSKVKNLTVGDRV--AIEPAC 263 G+V +GS V +L GDRV A+ P+C Sbjct: 72 GIVESVGSAVTSLRPGDRVVGALTPSC 98 >UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15; Mycobacterium|Rep: Zinc-binding dehydrogenase - Mycobacterium tuberculosis Length = 384 Score = 56.4 bits (130), Expect = 6e-07 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = +3 Query: 27 LRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 +R+ P P + D V++ + GICGSD+H+++ G + EP+ +GHEA G + + Sbjct: 12 VRVNTQPDPALPGPDGVVVAVTAAGICGSDLHFYE----GEYPFTEPVALGHEAVGTIVE 67 Query: 204 IGSKVKNLTVGDRVAIEPACRVGTASSVRQDD 299 G +V+ + VGD V + G D Sbjct: 68 AGPQVRTVGVGDLVMVSSVAGCGVCPGCETHD 99 >UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1; Acidobacteria bacterium Ellin345|Rep: Alcohol dehydrogenase GroES-like - Acidobacteria bacterium (strain Ellin345) Length = 350 Score = 56.4 bits (130), Expect = 6e-07 Identities = 27/84 (32%), Positives = 44/84 (52%) Frame = +3 Query: 39 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 218 + P+P+ +EVL+++ ICG+D+H + Q ++ P+I GHE G V +GS+V Sbjct: 21 EVPVPKFGPNEVLVKVKVASICGTDLHIYNWDQWAQRRIKPPLIPGHEFCGDVVAVGSEV 80 Query: 219 KNLTVGDRVAIEPACRVGTASSVR 290 + GD V+ E G R Sbjct: 81 TLVKEGDFVSAEMHVNCGKCLQCR 104 Score = 37.9 bits (84), Expect = 0.22 Identities = 25/102 (24%), Positives = 40/102 (39%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 V C C C+TG+ H+C + +G Y +KL + E ++L+P Sbjct: 95 VNCGKCLQCRTGQAHICQHVKIIGV-DANGAFAEYVVIPESNIWKLDPAIPQEYASILDP 153 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 L +H G ++A V + G P + K TK Sbjct: 154 LGNAVHTVLAGDIAA-KTVAITGCGPIGLFSIAVAKACGATK 194 >UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain protein; n=2; Bacteria|Rep: Alcohol dehydrogenase GroES domain protein - Solibacter usitatus (strain Ellin6076) Length = 339 Score = 56.4 bits (130), Expect = 6e-07 Identities = 27/85 (31%), Positives = 43/85 (50%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 PC C C+ G H+C ++ F G L + A +LPD +++ EGA++EP+ Sbjct: 89 PCGTCPACRMGHSHICHNLKFIGID-TPGALQGMWTVPAHTLHRLPDSLSLREGAMVEPI 147 Query: 443 AVGIHACKRGGVSAGHVVLVLGRDP 517 AV H + + AG +V+G P Sbjct: 148 AVACHDVRMSELQAGEFAVVIGGGP 172 Score = 54.4 bits (125), Expect = 2e-06 Identities = 26/74 (35%), Positives = 38/74 (51%) Frame = +3 Query: 69 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVA 248 +V + ++ GICG+D+H + L P +MGHE SG +A +G V GDRV Sbjct: 26 QVQINVEFCGICGTDLHLFHGAMAHRLTL--PHVMGHEMSGTLAAVGEGVAGWQAGDRVT 83 Query: 249 IEPACRVGTASSVR 290 + P GT + R Sbjct: 84 VRPLDPCGTCPACR 97 >UniRef50_A5VBI0 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Sphingomonas wittichii RW1|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Sphingomonas wittichii RW1 Length = 337 Score = 56.4 bits (130), Expect = 6e-07 Identities = 27/79 (34%), Positives = 45/79 (56%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 ND+R+ + P + +VL+R+ G+CGSD+ Y + G EP +GHE SG + Sbjct: 10 NDVRIDEIADPMVGPRDVLVRVRRCGLCGSDLGYIKAGGVA-MPATEPFGIGHELSGTIE 68 Query: 201 KIGSKVKNLTVGDRVAIEP 257 +G++V+ + G RV + P Sbjct: 69 AVGAEVRGIAPGLRVVVNP 87 Score = 35.9 bits (79), Expect = 0.88 Identities = 17/41 (41%), Positives = 23/41 (56%) Frame = +2 Query: 395 LPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 +PD V + AL EPLAV +HA +R G + V + G P Sbjct: 121 IPDPVGWDAAALAEPLAVALHAVRRSGATREDRVALFGVGP 161 >UniRef50_A1SI01 Cluster: Alcohol dehydrogenase GroES domain protein; n=23; Actinobacteria (class)|Rep: Alcohol dehydrogenase GroES domain protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 393 Score = 56.4 bits (130), Expect = 6e-07 Identities = 30/77 (38%), Positives = 45/77 (58%), Gaps = 1/77 (1%) Frame = +3 Query: 24 DLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 D+R+ + P P I E + ++R+ G+CGSD+H + F+ I+GHE GVV Sbjct: 11 DIRVEEVPDPRIEEPTDAIIRVTTTGLCGSDLHLYDP--LTPFMTPGD-IVGHEPMGVVE 67 Query: 201 KIGSKVKNLTVGDRVAI 251 +GS+V L VGDRV + Sbjct: 68 AVGSEVTELAVGDRVVV 84 >UniRef50_A7R304 Cluster: Chromosome undetermined scaffold_469, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_469, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 262 Score = 56.4 bits (130), Expect = 6e-07 Identities = 34/86 (39%), Positives = 44/86 (51%) Frame = +3 Query: 54 EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTV 233 E E +V ++ GIC SD+H K G P++ GHE GVV ++GSKV N V Sbjct: 34 ETGEKDVRFKVLYCGICHSDLHM-AKNDWGTSTY--PIVPGHETVGVVTEVGSKVNNFKV 90 Query: 234 GDRVAIEPACRVGTASSVRQDDTTYA 311 GD+V + C VG S R D A Sbjct: 91 GDKVGV--GCLVGACHSCRDVDQMQA 114 >UniRef50_A1D1F8 Cluster: Alcohol dehydrogenase; n=3; Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 378 Score = 56.4 bits (130), Expect = 6e-07 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +3 Query: 15 KPNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 191 +P ++ ++ P+P I ++ + ++R+ ICGSD+H++ G G P +GHEA G Sbjct: 19 QPYNVSVIDMPVPHIINQTDAIIRIPTSAICGSDLHFYH-GYSGS--PNVPWGLGHEAVG 75 Query: 192 VVAKIGSKVKNLTVGDRVAI 251 V+++GS V +L VGD V I Sbjct: 76 YVSEVGSAVSSLQVGDYVII 95 >UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured crenarchaeote 10-H-08|Rep: Dehydrogenase - uncultured crenarchaeote 10-H-08 Length = 366 Score = 56.4 bits (130), Expect = 6e-07 Identities = 30/81 (37%), Positives = 45/81 (55%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ + P DLR++ P EVL+R CG+D+ + +G H P+IMGHE Sbjct: 25 AVFHGPGDLRVMDVGRPSPGRGEVLVRTFVTLTCGTDLKMFLRG---HPYARPPVIMGHE 81 Query: 183 ASGVVAKIGSKVKNLTVGDRV 245 +GVV ++G +V + VGD V Sbjct: 82 FAGVVVEVGEEVDWVNVGDEV 102 Score = 48.4 bits (110), Expect = 2e-04 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Frame = +2 Query: 263 PCRYCEFCKTGRYHLCPDM----IFCATPPVHGNLVRYYKHAADF-CFKLPDHVTMEEGA 427 PC YC +CK GR++LC ++ I + + ++ + F +KLP + A Sbjct: 109 PCGYCIYCKLGRFNLCENLGETIIGFSVDGAYAEYIKLPRRIVTFNLYKLPKGLEPRVAA 168 Query: 428 LLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 LLEPLA + + + G V V+G P Sbjct: 169 LLEPLACVVRGQRLIHIDVGDAVAVVGAGP 198 >UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1; Salmonella typhi|Rep: Starvation sensing protein RspB - Salmonella typhi Length = 287 Score = 56.0 bits (129), Expect = 8e-07 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHE 182 ++ KPN L + + + + EV +++ GICGSD H ++ GH + P ++GHE Sbjct: 5 VIEKPNTLTIETRALLQPASGEVRIKVKLAGICGSDSHIYR----GHNPFAKYPRVIGHE 60 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 GV+ +G V +G+RV+++P G Sbjct: 61 FFGVIDAVGDNVNRDRIGERVSVDPVISCG 90 Score = 35.5 bits (78), Expect = 1.2 Identities = 19/102 (18%), Positives = 38/102 (37%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 439 + C +C C G+ ++C ++ G Y A ++PD++ ++EP Sbjct: 87 ISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSEYAVAPARNAHRIPDNIADHHAVMVEP 145 Query: 440 LAVGIHACKRGGVSAGHVVLVLGRDPSASLPCSQLKPLEHTK 565 + + + + V L+ G P LK + K Sbjct: 146 FTIAANVTGQVNPTEQDVALIYGAGPMGLTTVQALKGVYQVK 187 >UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogenase family; n=41; Bacteria|Rep: Oxidoreductase, zinc-binding dehydrogenase family - Burkholderia mallei (Pseudomonas mallei) Length = 353 Score = 56.0 bits (129), Expect = 8e-07 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 3/89 (3%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCP-DMIFCATPPV-HGNLVRYYK-HAADFCFKLPDHVTMEEGAL 430 VPC C +CK+G+Y +C IF V G + Y + + +P +++E+ A+ Sbjct: 97 VPCGTCRYCKSGQYWMCEVHHIFGFQREVADGGMAEYMRIPSGAIVHPIPLGISLEDAAI 156 Query: 431 LEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 +EPLA IH RG + VV++ G P Sbjct: 157 IEPLACAIHTVNRGDIQLDDVVVIAGAGP 185 Score = 38.3 bits (85), Expect = 0.17 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Frame = +3 Query: 12 YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSD--VHYWQKGQCG--HFVLEEPMIMGH 179 + P D R+ + P + E+++R+ GIC SD H K G ++ P+I GH Sbjct: 7 HAPEDYRVERVAKPRANARELVIRIGACGICASDCKCHAGAKMFWGGPSPWVKAPVIPGH 66 Query: 180 EASGVVAKIGSKVK---NLTVGDRVAIEPACRVGT 275 E G V +G + +GDRV E GT Sbjct: 67 EFFGYVEALGEGAAEHFGVALGDRVIAEQIVPCGT 101 >UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=2; Burkholderiales|Rep: Zinc-containing alcohol dehydrogenase superfamily - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 337 Score = 56.0 bits (129), Expect = 8e-07 Identities = 30/92 (32%), Positives = 52/92 (56%), Gaps = 2/92 (2%) Frame = +3 Query: 3 ALLY-KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-MIMG 176 A++Y +P+ + ++ +P++ E+LLR+D GICGSD+H + GH +P +++G Sbjct: 3 AIVYTQPDAVEVLDRDMPDLEPGEILLRIDASGICGSDLHAYH----GHDPRRKPGLVLG 58 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 HE +G V + + + VG RV P G Sbjct: 59 HEFAGTVIASSDEAR-MPVGQRVTANPLVTCG 89 Score = 36.7 bits (81), Expect = 0.51 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPD--MIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALL 433 V C +C++C GR +LC + M+ P G L Y +PD + AL Sbjct: 86 VTCGHCDYCLQGRDNLCANRGMVGMNRP---GALSEYLAIPIRCAIPIPDTLPSVSAALT 142 Query: 434 EPLAVGIHA 460 EP A +HA Sbjct: 143 EPAATALHA 151 >UniRef50_Q1ARB8 Cluster: Alcohol dehydrogenase, zinc-binding protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol dehydrogenase, zinc-binding protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 375 Score = 56.0 bits (129), Expect = 8e-07 Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 3/90 (3%) Frame = +3 Query: 3 ALLY-KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 ALLY + + R+ + + + ++EVL+ + G+C SD H G+ G L PMI GH Sbjct: 6 ALLYGEGQEFRVEEIEVDDPKQNEVLVHLAATGLCHSDYHM-VTGEYGP--LHFPMIGGH 62 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIE--PAC 263 E +GVV K+G V ++ GD V + PAC Sbjct: 63 EGAGVVEKVGPGVTRVSPGDHVLLTFIPAC 92 >UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain protein; n=10; Mycobacterium|Rep: Alcohol dehydrogenase GroES domain protein - Mycobacterium sp. (strain KMS) Length = 341 Score = 56.0 bits (129), Expect = 8e-07 Identities = 29/81 (35%), Positives = 39/81 (48%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C +C YHLC + +G L Y + ++PD V +EE AL EP A Sbjct: 89 CGSCHYCHRSLYHLCQRPGWIGFTR-NGGLANYVAVPSRLAVRVPDVVDLEEAALTEPTA 147 Query: 446 VGIHACKRGGVSAGHVVLVLG 508 V HA +R + G V+VLG Sbjct: 148 VAFHAVRRAELLLGETVMVLG 168 Score = 55.2 bits (127), Expect = 1e-06 Identities = 24/79 (30%), Positives = 43/79 (54%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 ND+ L P P + EV++ + G+CG+D+H + G + P+++GHE SG + Sbjct: 10 NDVGLTSVPDPAPQDGEVIIEVAATGLCGTDLHEYVAGPT---FSQPPVVLGHEVSGRIV 66 Query: 201 KIGSKVKNLTVGDRVAIEP 257 ++G+ V +G A+ P Sbjct: 67 EVGAGVDQSRIGQGAAVIP 85 >UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Nocardioides sp. JS614|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 351 Score = 56.0 bits (129), Expect = 8e-07 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Frame = +2 Query: 197 GQDRFESQESDSW*SSGHRAGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR----- 361 G D F + D + H A C C+ C G+Y+LC + A +G+ + Sbjct: 78 GADTFGWRVGDRVAGTSHSA---CGACQKCVEGQYNLCENYGRPALHAQYGHNAQGVNAT 134 Query: 362 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLG 508 Y H F+LPD V+ + GAL +P ++ +H +RG + G V V G Sbjct: 135 YAVHNVKSIFRLPDEVSFDVGALADPASIALHVARRGNIKPGDTVAVTG 183 Score = 55.6 bits (128), Expect = 1e-06 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 +PN L + + P+PE +EVL R+ V ICG+D H G + + P GHE +G Sbjct: 12 EPNVLEIAEVPVPEPGRNEVLARVRSVSICGTDAHLINGDYPGFWPPQFPFTPGHEWAGD 71 Query: 195 VAKIGSKVKNL--TVGDRVA 248 V +G VGDRVA Sbjct: 72 VVALGEGADTFGWRVGDRVA 91 >UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15; Proteobacteria|Rep: Alcohol dehydrogenase GroES-like - Burkholderia ambifaria MC40-6 Length = 358 Score = 56.0 bits (129), Expect = 8e-07 Identities = 34/95 (35%), Positives = 48/95 (50%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 P LR P +E E+LLR+ VGICG+D+H + Q L+ P +MGHE S +V Sbjct: 32 PGILRHEDRAPPSRAEGEILLRVQRVGICGTDMHIYSGNQP---YLQYPRVMGHELSAIV 88 Query: 198 AKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDT 302 A+ ++ GD V + P G + RQ T Sbjct: 89 AE-ADPGAHVAPGDAVYVMPYLSCGQCIACRQGKT 122 Score = 52.8 bits (121), Expect = 7e-06 Identities = 29/84 (34%), Positives = 44/84 (52%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C+ G+ + C ++ G L Y A F K + VT+++ A++E LA Sbjct: 111 CGQCIACRQGKTNCCVNIKVLGVHR-DGALTEYLSVPAQFVHKA-EGVTLDQAAMIEFLA 168 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 +G HA +R VSAG +LV+G P Sbjct: 169 IGAHAVRRAAVSAGQRILVVGAGP 192 >UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=1; Paracoccus denitrificans PD1222|Rep: Zinc-containing alcohol dehydrogenase superfamily - Paracoccus denitrificans PD1222 Length = 237 Score = 55.6 bits (128), Expect = 1e-06 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 8/86 (9%) Frame = +3 Query: 24 DLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-------MIMGH 179 DLR+ P P E + DEV++ GICG+D+H + G FV ++ ++GH Sbjct: 11 DLRVEDIPQPTEPAADEVVIENRFAGICGTDLHEYAYGPI--FVPKDAATGAVAAQVLGH 68 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 E G V K+G V ++ VGDRV+++P Sbjct: 69 EYGGTVVKVGRDVTHVKVGDRVSVQP 94 Score = 50.8 bits (116), Expect = 3e-05 Identities = 26/75 (34%), Positives = 38/75 (50%) Frame = +2 Query: 293 GRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRG 472 G+++L M + G + +KLPD +T E+ AL+EP+AV ++ RG Sbjct: 108 GQFNLSDAMALAGLSWIGGGMAESSLLKGYNVYKLPDQMTDEDAALVEPVAVAVYGVDRG 167 Query: 473 GVSAGHVVLVLGRDP 517 GV G VLV G P Sbjct: 168 GVKPGDAVLVTGAGP 182 >UniRef50_Q0RIJ3 Cluster: Putative Zn-dependent alcohol dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative Zn-dependent alcohol dehydrogenase - Frankia alni (strain ACN14a) Length = 317 Score = 55.6 bits (128), Expect = 1e-06 Identities = 27/82 (32%), Positives = 45/82 (54%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 LR V+ P P +V++ + G+C +D+ + G+ P+++GHE +GVVA++ Sbjct: 19 LRPVELPDPVAGPGQVVVDVRAAGLCHTDISF-MNGEVPGMPSHLPIVLGHEIAGVVAEL 77 Query: 207 GSKVKNLTVGDRVAIEPACRVG 272 G+ V VG+RV I P G Sbjct: 78 GAGVTGFAVGERVGIAPVLHDG 99 >UniRef50_A7NMA5 Cluster: Alcohol dehydrogenase GroES domain protein; n=2; Chloroflexaceae|Rep: Alcohol dehydrogenase GroES domain protein - Roseiflexus castenholzii DSM 13941 Length = 370 Score = 55.6 bits (128), Expect = 1e-06 Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Frame = +3 Query: 3 ALLYKPND--LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 173 AL +P +RLVQ P PEI+ DEVL+R+ VGICG+D G+ +++ Sbjct: 3 ALAVQPGSAGIRLVQRPQPEITRPDEVLVRIIRVGICGTDREIVSGGRAKASDHATDLVI 62 Query: 174 GHEASGVVAKIGSKVKNLTVGD 239 GHE G V +GS V+ + VGD Sbjct: 63 GHEMFGRVEAVGSAVQRVHVGD 84 >UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=5; Bacteria|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Flavobacterium johnsoniae UW101 Length = 356 Score = 55.6 bits (128), Expect = 1e-06 Identities = 33/92 (35%), Positives = 47/92 (51%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 KP + +L + IPE E EVLL++ +GICG+D+H + G +F E P I+GHE + Sbjct: 27 KPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAF-GGTQPYF--EYPRILGHELAAE 83 Query: 195 VAKIGSKVKNLTVGDRVAIEPACRVGTASSVR 290 K GD+V P GT + R Sbjct: 84 YVK--GNAAGFKPGDKVTFIPYFNCGTCVACR 113 Score = 37.9 bits (84), Expect = 0.22 Identities = 22/84 (26%), Positives = 36/84 (42%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C+ G + C ++ + G + Y + + +E AL+EPLA Sbjct: 106 CGTCVACRNGLTNCCVNIKVFGVH-IDGGMAEYVSIPEQYLLH-GQGLDYDELALVEPLA 163 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 + H +R V + VLV+G P Sbjct: 164 IAAHGVRRAAVKSTDTVLVMGAGP 187 >UniRef50_A1SJ83 Cluster: Alcohol dehydrogenase GroES domain protein; n=12; Bacteria|Rep: Alcohol dehydrogenase GroES domain protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 354 Score = 55.6 bits (128), Expect = 1e-06 Identities = 34/106 (32%), Positives = 47/106 (44%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 +D L +PE DEVL+++ G C SD+H + + G P +GHE +G V Sbjct: 11 SDPVLEDVAVPEPGPDEVLVQVGGAGACHSDLHLMHEFEPGTLPWSPPFTLGHENAGWVH 70 Query: 201 KIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYALT*SSAPRP 338 +G+ V L G VA+ A G R TY AP P Sbjct: 71 TVGTGVTGLEPGQPVAVVGAWGCGVCDRCRAGVETYCERPDLAPVP 116 >UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1; Arthrobacter aurescens TC1|Rep: L-threonine 3-dehydrogenase - Arthrobacter aurescens (strain TC1) Length = 347 Score = 55.6 bits (128), Expect = 1e-06 Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 1/85 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C C+TG H C + + G Y D C KLP +++E GALLE Sbjct: 95 CGQCFPCRTGDAHTC-ERTGILGMHIDGVFAEYAAVPQDICVKLPTGLSLESGALLEAAG 153 Query: 446 VGIHACKRGGVS-AGHVVLVLGRDP 517 V +HA +R S AG VLV G P Sbjct: 154 VAVHAIQRANYSVAGRAVLVSGAGP 178 Score = 53.2 bits (122), Expect = 5e-06 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGH-FVLEEPMIMGHEASGVVAKIGSKVKNL 227 P+ +E V++ + +CG+D ++ F L P+++GHE +G V +IG V L Sbjct: 22 PKATEGSVVIEVGAASLCGTDRELYEWTPSAQAFNLNLPVVLGHEGAGTVVEIGPGVTGL 81 Query: 228 TVGDRVAIEPACRVGTASSVRQDD 299 VGD+VA+E G R D Sbjct: 82 KVGDQVALESHLTCGQCFPCRTGD 105 >UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 391 Score = 55.6 bits (128), Expect = 1e-06 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 7/87 (8%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG-----QCGHFVLE--EPMIMG 176 P D+R+ Q P + +V LR GICGSD+H + G + H + + P++MG Sbjct: 25 PRDVRVEQIEEPVCGKGQVKLRNTYCGICGSDLHEYTSGPVLIPKGAHSITKATAPVVMG 84 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEP 257 HE GVV ++G + +L G + + P Sbjct: 85 HEFGGVVEEVGEGITHLKPGQKAVVRP 111 Score = 39.9 bits (89), Expect = 0.054 Identities = 20/47 (42%), Positives = 27/47 (57%) Frame = +2 Query: 377 ADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 A+ + +PD+VT E A++EPLAV HA G VLV+G P Sbjct: 174 AEHFYPIPDNVTPESMAMIEPLAVAWHAVNLSPFKEGDNVLVVGGGP 220 >UniRef50_Q5B536 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 664 Score = 55.6 bits (128), Expect = 1e-06 Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 10/95 (10%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG-------QCGHFVLEE 161 A Y D+R+ P+P+ S+D VL+ ++ GICGSD++ + G Q G L Sbjct: 507 AQFYAAGDVRVEDVPVPQASDDRVLIEVEWCGICGSDLNEYMFGPFAIPSLQSGPHPLTN 566 Query: 162 ---PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEP 257 P+ MGHE +G + + + +L G V ++P Sbjct: 567 ALLPVTMGHEFTGRIKYVPESISHLKKGQAVVVDP 601 >UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase; possible sorbitol dehydrogenase; n=3; Bacillus cereus|Rep: Zinc-containing alcohol dehydrogenase; possible sorbitol dehydrogenase - Bacillus cereus (strain ZK / E33L) Length = 340 Score = 55.2 bits (127), Expect = 1e-06 Identities = 27/85 (31%), Positives = 46/85 (54%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+ Y D+R+ + E+ ++V +++ GICGSD+H + + + ++GHE Sbjct: 4 AVWYGEKDIRIEERETKELQPNDVKVKVAWAGICGSDLHAYLHPDS--VPMNKNTVLGHE 61 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEP 257 SG + ++GS V GDRV I P Sbjct: 62 FSGEIVEVGSHVTKFKEGDRVCIYP 86 Score = 41.1 bits (92), Expect = 0.024 Identities = 19/59 (32%), Positives = 29/59 (49%) Frame = +2 Query: 341 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 + G Y FK+PD++++E A++EP AV + K V G V+V G P Sbjct: 110 IDGGFAEYVILPQKTIFKIPDNLSLEVAAMVEPAAVSFQSIKDSNVEEGDTVVVYGAGP 168 >UniRef50_Q0K0E7 Cluster: Zinc-type alcohol dehydrogenase adhd; n=1; Ralstonia eutropha H16|Rep: Zinc-type alcohol dehydrogenase adhd - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 368 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/90 (31%), Positives = 51/90 (56%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A++ K +L++ + E ++EV++ + G+C SD+ +Q P+I+GHE Sbjct: 8 AVMVKARELQVELLDLDEPHDNEVMVEIAATGVCHSDLSVYQ----AVLPTPLPVILGHE 63 Query: 183 ASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 ++GVV +GS+V L +GDRV + + G Sbjct: 64 SAGVVVGLGSQVSGLALGDRVVLSLLAQCG 93 >UniRef50_A6PRU8 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Victivallis vadensis ATCC BAA-548|Rep: Alcohol dehydrogenase GroES domain protein - Victivallis vadensis ATCC BAA-548 Length = 328 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/76 (36%), Positives = 42/76 (55%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 197 P +V PIPEI++D++L+++ G+C S+ + W Q G + GHE+ GVV Sbjct: 9 PRKSEVVDVPIPEITDDQLLVKVTYTGMCHSEWYPWTVAQPGE-------LFGHESVGVV 61 Query: 198 AKIGSKVKNLTVGDRV 245 A+ G V GDRV Sbjct: 62 ARCGRNVTGFKEGDRV 77 >UniRef50_A5V832 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Sphingomonas wittichii RW1|Rep: Alcohol dehydrogenase GroES domain protein - Sphingomonas wittichii RW1 Length = 372 Score = 55.2 bits (127), Expect = 1e-06 Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Frame = +3 Query: 3 ALLYKP-NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHY-WQKGQCGHFVLEEPMIMG 176 ALL++ N RL + + E EVL+R+ GICGSD+H + G + P+I+G Sbjct: 4 ALLHQDSNTPRLEEVAVEEPRFGEVLVRIAASGICGSDLHVVHNRSNVGK---DRPVILG 60 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAI 251 HE +GVV +G V++L GD V + Sbjct: 61 HEGAGVVEAVGPGVRDLKRGDHVVM 85 >UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 351 Score = 55.2 bits (127), Expect = 1e-06 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS---GVV 197 L + P+ +EVL+++ GICGSD H W + +I+GHE++ G++ Sbjct: 15 LAIQDRPVTPPGPNEVLVQVISTGICGSDTHNWNNPN-----VSRELILGHESAGLRGLI 69 Query: 198 AKIGSKVKNLTVGDRVAIEPACRVGTASSVRQDDTTYAL 314 +I S+VK+ VG R+A+EP T + + L Sbjct: 70 VEIDSEVKDRHVGQRMAVEPGFACATRKCPDNQEDAFCL 108 Score = 51.6 bits (118), Expect = 2e-05 Identities = 19/68 (27%), Positives = 35/68 (51%) Frame = +2 Query: 281 FCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 460 FC G + C ++ +C P G L +Y+ A +P+ ++ EE ++PLA+ + Sbjct: 106 FCLRGNPNTCANLKYCGLDPTDGTLQQYFTCKAHMAIPIPEEISWEEAGAIQPLAIAVQL 165 Query: 461 CKRGGVSA 484 +R +SA Sbjct: 166 ARRAALSA 173 Score = 41.5 bits (93), Expect = 0.018 Identities = 21/41 (51%), Positives = 26/41 (63%) Frame = +1 Query: 541 AKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAE 663 AKA+G K+++ DI QSRLDFA S G D +L K S E Sbjct: 194 AKAYGVCKIVVFDIEQSRLDFALSYGEDIGVLSPKISENVE 234 >UniRef50_A4RNL2 Cluster: Putative uncharacterized protein; n=3; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 410 Score = 55.2 bits (127), Expect = 1e-06 Identities = 33/71 (46%), Positives = 42/71 (59%), Gaps = 2/71 (2%) Frame = +3 Query: 45 PIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEASGVVAKIGSKV 218 P PE+ E E ++R+ ICGSD+H ++ G + E P GHEA GVV KIG V Sbjct: 38 PFPELKEPEDAIVRITTSAICGSDLHNYR----GFYGPENYPYRAGHEAMGVVHKIGPAV 93 Query: 219 KNLTVGDRVAI 251 +L VGDRV I Sbjct: 94 DSLKVGDRVVI 104 >UniRef50_A3H5I8 Cluster: Alcohol dehydrogenase GroES-like; n=1; Caldivirga maquilingensis IC-167|Rep: Alcohol dehydrogenase GroES-like - Caldivirga maquilingensis IC-167 Length = 346 Score = 55.2 bits (127), Expect = 1e-06 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 6/86 (6%) Frame = +3 Query: 27 LRLVQTPIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 LRL + E DE VL+++ G+C +DV W KG + P ++GHE +G+V + Sbjct: 15 LRLESIDVKEPGNDESVLVKVIGAGMCKTDVRLW-KGTEPREGFKLPFVLGHENAGIVEE 73 Query: 204 IGSKVKNLTVGDRVAI-----EPACR 266 +G KVK L GD+V + +P C+ Sbjct: 74 VGGKVKGLKPGDKVLVYAIWADPGCK 99 >UniRef50_P77316 Cluster: Uncharacterized zinc-type alcohol dehydrogenase-like protein ybdR; n=48; Proteobacteria|Rep: Uncharacterized zinc-type alcohol dehydrogenase-like protein ybdR - Escherichia coli (strain K12) Length = 412 Score = 55.2 bits (127), Expect = 1e-06 Identities = 32/85 (37%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Frame = +3 Query: 3 ALLYK-PNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 176 AL Y P+ +++ P P + + D+++LR+ ICGSD+H + +G+ ++ I G Sbjct: 3 ALTYHGPHHVQVENVPDPGVEQADDIILRITATAICGSDLHLY-RGKIPQ--VKHGDIFG 59 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAI 251 HE G V + G VKNL GDRV I Sbjct: 60 HEFMGEVVETGKDVKNLQKGDRVVI 84 >UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogenase family; n=28; Bacteria|Rep: Oxidoreductase, zinc-binding dehydrogenase family - Burkholderia mallei (Pseudomonas mallei) Length = 378 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAAD-FCFKLPDHVTMEEGALL 433 VPC C FC G+Y +C ++ VHG + Y + ++PD + +E L+ Sbjct: 122 VPCWSCRFCGHGQYWMCQKHDLYGFQNNVHGAMAEYMIFTKEAIVHRVPDSIPTDEAILI 181 Query: 434 EPLAVGIHACKRGGVSAGHVVLVLG 508 EPL+ +HA R V VV+V G Sbjct: 182 EPLSCSLHAADRANVGFDDVVVVAG 206 Score = 48.4 bits (110), Expect = 2e-04 Identities = 33/88 (37%), Positives = 47/88 (53%), Gaps = 9/88 (10%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDV-------HYWQKGQCGHFVLEEPMIMG 176 P D RL Q P+P+ DE+L +++ VGIC D+ +W +V + PMI G Sbjct: 33 PQDYRLEQVPVPKPGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYV-KPPMIPG 91 Query: 177 HE-ASGVVA-KIGSKVKNLTVGDRVAIE 254 HE VVA G++ + + VGDRV E Sbjct: 92 HEFVCRVVALGPGAERRGVKVGDRVISE 119 >UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine dehydrogenase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strong similarity to L-threonine dehydrogenase - Candidatus Kuenenia stuttgartiensis Length = 344 Score = 54.8 bits (126), Expect = 2e-06 Identities = 26/80 (32%), Positives = 44/80 (55%) Frame = +3 Query: 15 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 194 + + L LV+ P P++ +VL+++ ICG+DVH P I+GHE +G Sbjct: 9 RASGLELVKMPEPKLGPKDVLIKVQVASICGTDVHIDDWTYWAQQRFTPPRIIGHEFAGY 68 Query: 195 VAKIGSKVKNLTVGDRVAIE 254 V ++G +V + G+RV+ E Sbjct: 69 VQEVGKEVTFVKAGERVSAE 88 >UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Alcohol dehydrogenase GroES domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 338 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/79 (35%), Positives = 40/79 (50%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 ND+R+ + P E+LL++ GICGSDV W + P++ GHE V Sbjct: 10 NDIRIEEVATPRPGPKEMLLKVASCGICGSDVVEWYRKP------RAPLVQGHEIGAEVV 63 Query: 201 KIGSKVKNLTVGDRVAIEP 257 ++GS V VG+RV P Sbjct: 64 EVGSSVTGFKVGERVFAVP 82 Score = 50.0 bits (114), Expect = 5e-05 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +2 Query: 260 VPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF-CFKLPDHVTMEEGALLE 436 VPC C +C+ G Y C + I P + + + + LPD +T ++ +E Sbjct: 84 VPCMECHYCRNGHYPQCAE-IKVRLPGGFAEYILVPEILVEKGTYHLPDTITYDQSTFIE 142 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PLA + A + G+ AG V+VLG Sbjct: 143 PLACVVRAQRLAGIRAGQTVVVLG 166 >UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol dehydrogenases; n=2; Ostreococcus|Rep: COG1064: Zn-dependent alcohol dehydrogenases - Ostreococcus tauri Length = 1719 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/83 (36%), Positives = 46/83 (55%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A L + DL ++ +P+++ V LR++ G+CGSD H G G + + P + GHE Sbjct: 1378 AALAQNEDLVPIKYRLPDMTPSSVELRVEYCGLCGSDDHLIV-GDYGEYAVW-PQVCGHE 1435 Query: 183 ASGVVAKIGSKVKNLTVGDRVAI 251 GVV ++GS V L G RV + Sbjct: 1436 VVGVVTQVGSAVTTLKPGQRVGV 1458 Score = 33.9 bits (74), Expect = 3.6 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Frame = +2 Query: 245 GHRAGV-----PCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAADFCFKLPDH 406 G R GV C CE+C G LC + C G R + A FC+K+PD Sbjct: 1453 GQRVGVGWQSSSCHDCEWCARGDEQLCSAVGCTCCEGNKGGFADRMRLNDAQFCYKIPDE 1512 Query: 407 VTMEEGALL 433 + E A L Sbjct: 1513 LASAEVAPL 1521 >UniRef50_Q5KJW4 Cluster: Zinc-type alcohol dehydrogenase, putative; n=2; Basidiomycota|Rep: Zinc-type alcohol dehydrogenase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 54.8 bits (126), Expect = 2e-06 Identities = 26/76 (34%), Positives = 43/76 (56%) Frame = +3 Query: 24 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 203 + L + + + +D + + ++C G+CGSD H+ G G F + ++ GHE G V + Sbjct: 19 NFELKKYELEPLEDDRITVAVECCGVCGSD-HHTISGGWGPFQTKF-VVTGHEVVGKVVE 76 Query: 204 IGSKVKNLTVGDRVAI 251 +GSKV VGDRV + Sbjct: 77 VGSKVSEFKVGDRVGV 92 >UniRef50_Q2HBT9 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 378 Score = 54.8 bits (126), Expect = 2e-06 Identities = 37/91 (40%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Frame = +3 Query: 36 VQTPIP--EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIG 209 V TPI ++ DE+L+ M GIC +D Y Q+G G + P I GHE +G++ IG Sbjct: 20 VMTPITIHDLRSDEILVEMKYSGICHTDF-YLQQGGFGPLT-QFPAIAGHEGAGIIRGIG 77 Query: 210 SKVKN--LTVGDRVAIEPACRVGTASSVRQD 296 S VKN L VGD V + A G S ++D Sbjct: 78 SNVKNKSLQVGDSVLLSFAA-CGECSHCQED 107 >UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4; Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 375 Score = 54.8 bits (126), Expect = 2e-06 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 7/87 (8%) Frame = +3 Query: 18 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC-----GHFV--LEEPMIMG 176 P D+R+ + P + +V LR VGICGSD+H + G H + P+ +G Sbjct: 30 PGDIRIEEIDEPTCGKGQVKLRPAFVGICGSDLHEYSAGPVLIPKEPHKITGTSYPVTLG 89 Query: 177 HEASGVVAKIGSKVKNLTVGDRVAIEP 257 HE +G+V ++G V +L+ G R + P Sbjct: 90 HEFAGIVEEVGEGVTHLSPGQRAVVRP 116 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/83 (33%), Positives = 42/83 (50%) Frame = +2 Query: 269 RYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAV 448 R C CK G + C ++ F G + ++ A+ + LPD+V++E AL+EPLAV Sbjct: 121 RQCCSCKLGYEYCCENIGFIGLSGYGGGMAKHTVAPAEHFYPLPDNVSLEAAALIEPLAV 180 Query: 449 GIHACKRGGVSAGHVVLVLGRDP 517 HA G V+V+G P Sbjct: 181 AWHAVNLSPFKGGDNVMVVGGGP 203 >UniRef50_Q9A414 Cluster: Alcohol dehydrogenase class III; n=8; Proteobacteria|Rep: Alcohol dehydrogenase class III - Caulobacter crescentus (Caulobacter vibrioides) Length = 366 Score = 54.4 bits (125), Expect = 2e-06 Identities = 25/67 (37%), Positives = 41/67 (61%), Gaps = 2/67 (2%) Frame = +3 Query: 69 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRV- 245 EVL+R G+C SD+H+ + G + P ++GHE++G+V +GS+V+ + VGD V Sbjct: 27 EVLIRTKAAGVCHSDLHFVE----GSYTHALPAVLGHESAGIVEAVGSEVRTVKVGDHVI 82 Query: 246 -AIEPAC 263 + P C Sbjct: 83 TCLNPYC 89 >UniRef50_Q74FN3 Cluster: Alcohol dehydrogenase, zinc-containing; n=71; cellular organisms|Rep: Alcohol dehydrogenase, zinc-containing - Geobacter sulfurreducens Length = 330 Score = 54.4 bits (125), Expect = 2e-06 Identities = 31/75 (41%), Positives = 42/75 (56%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 LR V+ P+PE EVLL++ GIC +DVH G+ L P+I GH+ G VAK+ Sbjct: 13 LRPVRVPVPEPGPGEVLLKVHACGICRTDVHI-VDGELTEPAL--PLIPGHQIVGSVAKL 69 Query: 207 GSKVKNLTVGDRVAI 251 G V+ G RV + Sbjct: 70 GEGVERFREGTRVGV 84 Score = 33.5 bits (73), Expect = 4.7 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 5/57 (8%) Frame = +2 Query: 245 GHRAGVP-----CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLP 400 G R GVP C C +C++GR +LC F G + A FCF +P Sbjct: 79 GTRVGVPWLGATCGACRYCRSGRENLCDHARFTGYQR-DGGFAEFTVADARFCFPIP 134 >UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing; n=3; Dehalococcoides|Rep: Alcohol dehydrogenase, zinc-containing - Dehalococcoides sp. (strain CBDB1) Length = 343 Score = 54.4 bits (125), Expect = 2e-06 Identities = 33/89 (37%), Positives = 46/89 (51%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 LL KP +LRL + P + VLL++ C ICG+DV +++ GH LE P I+GHE Sbjct: 5 LLEKPGELRLAEVVTPYCPKGGVLLKVLCCAICGTDVKMFRR---GHRDLEYPRILGHEI 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 + V G + G RV + P G Sbjct: 62 AAEVVCSGH--PDFEAGCRVQVYPGIACG 88 Score = 44.4 bits (100), Expect = 0.003 Identities = 32/91 (35%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFK----LPDHVTMEEG 424 G+ C C C GR +LC + G L Y + +P+HV+ EE Sbjct: 84 GIACGVCPLCLQGRENLCRKVKIIGFN-YDGGLAEYMALPPESLPVGLNIIPEHVSDEEA 142 Query: 425 ALLEPLAVGIHACKRGGVSAGHVVLVLGRDP 517 +L EPLA IHA V G VLVLG P Sbjct: 143 SLAEPLASCIHAQSVCRVGDGDRVLVLGAGP 173 >UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing; n=1; Pelodictyon luteolum DSM 273|Rep: Alcohol dehydrogenase, zinc-containing - Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM273)) Length = 323 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/89 (35%), Positives = 41/89 (46%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 LL P L ++ PIP E EVLLR+ IC +D W GH L P ++GHE Sbjct: 5 LLCGPKSLSILDRPIPIPGEGEVLLRVRAAAICRTDAKMWSS---GHRDLRLPRVLGHEV 61 Query: 186 SGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 SG + ++ L G ACR G Sbjct: 62 SGTIEGNPGQLYALWPGQACGSCMACRSG 90 Score = 51.2 bits (117), Expect = 2e-05 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G C C C++GR +LCPDM G + ++P+ V L E Sbjct: 78 GQACGSCMACRSGRQNLCPDMRITGFHR-DGGFAEFLTAPRSSLLEVPEGVGPVMATLAE 136 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PLA +H ++GGVS+ VL+ G Sbjct: 137 PLACAVHGVRQGGVSSRERVLIYG 160 >UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=1; Frankia sp. EAN1pec|Rep: Zinc-containing alcohol dehydrogenase superfamily - Frankia sp. EAN1pec Length = 350 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM----- 167 A L+ P DLR+ + PE + EV + + G+CG+D+ G + P+ Sbjct: 4 ARLHGPGDLRVEEVDEPEAAAGEVKIAVAHNGLCGTDLTEIFSGPRACTTVPHPLTGGVL 63 Query: 168 --IMGHEASGVVAKIGSKVKNLTVGDRVAIEPACRVG 272 I+GHE +GVVA +G+ V ++ V +RV++EP G Sbjct: 64 PQIVGHEFAGVVAAVGAGVTDVAVSERVSVEPLYSCG 100 Score = 48.4 bits (110), Expect = 2e-04 Identities = 26/84 (30%), Positives = 39/84 (46%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C C+ C+ LC ++ G L ++ +LP +++ EGAL+EP+A Sbjct: 99 CGDCDRCQASLPELCRQVMTHGICSNGGGLAQFTTVPRAMVHRLPASMSLAEGALVEPMA 158 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 V + R GV AG LV G P Sbjct: 159 VAFNGVLRSGVEAGGSALVFGAGP 182 >UniRef50_Q1LNT3 Cluster: Alcohol dehydrogenase GroES-like protein; n=3; Proteobacteria|Rep: Alcohol dehydrogenase GroES-like protein - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 353 Score = 54.4 bits (125), Expect = 2e-06 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 179 A+ Y P D+R P P I D E+L+++ ICGSD+H + +G + + GH Sbjct: 4 AVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLY-RGALDGIMEKGKSQTGH 62 Query: 180 EASGVVAKIGSKVKNLTVGDRVAI 251 E G V ++G V GDRV++ Sbjct: 63 ELIGEVVEVGKSVGRFKQGDRVSM 86 >UniRef50_Q1A676 Cluster: Alcohol dehydrogenase; n=4; Bacteria|Rep: Alcohol dehydrogenase - Roseburia inulinivorans Length = 403 Score = 54.4 bits (125), Expect = 2e-06 Identities = 24/78 (30%), Positives = 48/78 (61%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L + + + P+PE+ +D++L++++ G+CG+D H +++ F L P+ +GHE Sbjct: 44 AMLTELEKFEIKEFPMPEVGDDDILVKVEGCGVCGTDAHEFKRDP---FSL-IPVALGHE 99 Query: 183 ASGVVAKIGSKVKNLTVG 236 +G + K+G VK + G Sbjct: 100 GTGEIVKMGKNVKKDSAG 117 >UniRef50_Q0S7E4 Cluster: Possible alcohol dehydrogenase; n=2; Nocardiaceae|Rep: Possible alcohol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 355 Score = 54.4 bits (125), Expect = 2e-06 Identities = 27/93 (29%), Positives = 43/93 (46%) Frame = +3 Query: 30 RLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIG 209 R+V+ P+PE ++LLR++ G+C SD+H G F P +GHE +G V G Sbjct: 19 RVVRIPVPEPRGHQLLLRVEAAGLCRSDLHV-MDAPAGVFDYPLPFTLGHEVAGTVVGAG 77 Query: 210 SKVKNLTVGDRVAIEPACRVGTASSVRQDDTTY 308 +G+ V + G + R+ Y Sbjct: 78 PSADKSWIGESVVVHGVWSCGQCRNCRRSRENY 110 >UniRef50_A5V7S4 Cluster: Alcohol dehydrogenase, zinc-binding domain protein; n=1; Sphingomonas wittichii RW1|Rep: Alcohol dehydrogenase, zinc-binding domain protein - Sphingomonas wittichii RW1 Length = 360 Score = 54.4 bits (125), Expect = 2e-06 Identities = 31/75 (41%), Positives = 42/75 (56%) Frame = +3 Query: 21 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 200 +DL + I DEVL+R G+C +D+ YW G+ H + PMI+GHE G+V Sbjct: 11 SDLIIEDVEIDTPRTDEVLIRTVASGLCHTDLTYWG-GRHPHPL---PMILGHEGCGIVE 66 Query: 201 KIGSKVKNLTVGDRV 245 IG V N+ VGD V Sbjct: 67 AIGPGVTNVAVGDAV 81 >UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase; n=1; Bacillus megaterium|Rep: Zinc-containing alcohol dehydrogenase - Bacillus megaterium Length = 343 Score = 54.4 bits (125), Expect = 2e-06 Identities = 30/79 (37%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = +3 Query: 51 PEISEDEVLLRMDCVGICGSDVH-YWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNL 227 P I + E L+++ GICG+D+ Y+ K H + P+ MGHE SGV+ +I + + Sbjct: 20 PVIKKGEALVKVSHAGICGTDMMIYFGK----HPRAQAPLTMGHEFSGVIEEIRGETE-F 74 Query: 228 TVGDRVAIEPACRVGTASS 284 ++GDRVA+EP GT + Sbjct: 75 SLGDRVAVEPTLSCGTCEA 93 Score = 50.0 bits (114), Expect = 5e-05 Identities = 23/84 (27%), Positives = 39/84 (46%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLA 445 C CE C G++H+C + G ++ + LP+ ++ E AL EP+A Sbjct: 88 CGTCEACVKGQFHVCKQLKLIGIDQ-DGGFAQHVAVPVNRLHLLPEKLSSEHAALAEPVA 146 Query: 446 VGIHACKRGGVSAGHVVLVLGRDP 517 V +H +R + G ++LG P Sbjct: 147 VAVHTVRRSRLKVGDQAVILGAGP 170 >UniRef50_Q9WYP3 Cluster: Alcohol dehydrogenase, zinc-containing; n=2; Thermotoga|Rep: Alcohol dehydrogenase, zinc-containing - Thermotoga maritima Length = 395 Score = 54.0 bits (124), Expect = 3e-06 Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 6/86 (6%) Frame = +3 Query: 24 DLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEE----PMIMGHEAS 188 ++R+ + P P I + E+++++ GICGSDVH Q + G+ + P+ +GHE S Sbjct: 39 EVRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFS 98 Query: 189 GVVAKIGSKVKNLTVGDRVAI-EPAC 263 GVV + G + N R I EP C Sbjct: 99 GVVVEAGPEAINRRTNKRFEIGEPVC 124 >UniRef50_Q6NC01 Cluster: Possible alcohol dehydrogenase class III family; n=2; Rhodopseudomonas palustris|Rep: Possible alcohol dehydrogenase class III family - Rhodopseudomonas palustris Length = 370 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Frame = +3 Query: 27 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 206 LR+ + + EVL+R+ +G+C +D H +G+ V +PM++GHEA+G+V I Sbjct: 15 LRVERIVLDPPQPTEVLVRLAAIGLCRTDYHV-MRGE--RRVAMQPMVLGHEAAGIVEAI 71 Query: 207 GSKVKNLTVGDRVAIE--PAC 263 G +V+ + GD V + P C Sbjct: 72 GDQVQGVAPGDHVVLTFIPGC 92 >UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase superfamily; n=3; Chlorobiaceae|Rep: Zinc-containing alcohol dehydrogenase superfamily - Chlorobium limicola DSM 245 Length = 421 Score = 54.0 bits (124), Expect = 3e-06 Identities = 29/84 (34%), Positives = 36/84 (42%) Frame = +2 Query: 257 GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE 436 G+ C C FC GR +LC M G Y +PD + ME AL E Sbjct: 176 GISCGSCAFCLAGRENLCASMQILGFHH-DGGFAEYVAVRRTSLLSVPDTLPMELAALAE 234 Query: 437 PLAVGIHACKRGGVSAGHVVLVLG 508 PL +H R GV +G VL+ G Sbjct: 235 PLGCALHGLDRAGVRSGERVLIYG 258 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/62 (40%), Positives = 34/62 (54%) Frame = +3 Query: 6 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 185 +L +P L L + PE EDE L+R+ C +C +D WQ GH L P ++GHE Sbjct: 106 VLKEPRSLGLCERNDPETGEDEALVRVVCCSVCRTDAKMWQS---GHRDLVMPRVLGHEI 162 Query: 186 SG 191 SG Sbjct: 163 SG 164 >UniRef50_A7B0E7 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 406 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/87 (32%), Positives = 50/87 (57%), Gaps = 6/87 (6%) Frame = +3 Query: 3 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 182 A+L + + + P+PE+ + ++L++++ GICG+D H ++K G P+ +GHE Sbjct: 47 AMLTALENYEVKEFPMPEVGDGDILVKVEGCGICGTDAHEFKKDPFGLI----PVALGHE 102 Query: 183 ASGVVAKIGSKV------KNLTVGDRV 245 +G + K+G V K L VGD+V Sbjct: 103 GTGEIVKMGKNVKVDSAGKPLKVGDKV 129 >UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Alcohol dehydrogenase GroES domain protein - Clostridium beijerinckii NCIMB 8052 Length = 349 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 1/73 (1%) Frame = +3 Query: 57 ISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASGVVAKIGSKVKNLTV 233 I+ ++V++ + GICG+DV G + V + + +GHE++G++A++GS+VKN+ V Sbjct: 23 INPNDVIVDIKYCGICGTDVGII----AGTYPVAVKGVTLGHESTGIIAEVGSEVKNVKV 78 Query: 234 GDRVAIEPACRVG 272 GDRV I P G Sbjct: 79 GDRVVINPTYYCG 91 Score = 38.7 bits (86), Expect = 0.13 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Frame = +2 Query: 266 CRYCEFCKTGRYHLCPDMIFCATPPVH-GNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 442 C C C+T R + C + + + G Y+ +DF +K+PD V+M+ L EPL Sbjct: 90 CGKCRMCQTLRINHCENKFGTESGVSYDGTYADRYRTTSDFVYKIPDGVSMKAVTLTEPL 149 Query: 443 AVGIHACKR 469 + I ++ Sbjct: 150 SCVITGARK 158 >UniRef50_A2R610 Cluster: Catalytic activity:; n=5; Trichocomaceae|Rep: Catalytic activity: - Aspergillus niger Length = 356 Score = 54.0 bits (124), Expect = 3e-06 Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 8/86 (9%) Frame = +3 Query: 24 DLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKG-----QCGHFVLEE--PMIMGH 179 D+R+ + P EV +R VGICGSD+H + G H + E P+ +GH Sbjct: 11 DIRVEEIQEPGSCGVGEVKIRPAFVGICGSDIHEYLHGPSTIPSTTHPITGEKIPVTLGH 70 Query: 180 EASGVVAKIGSKVKNLTVGDRVAIEP 257 E SG + ++G V L VGD VAI+P Sbjct: 71 EFSGTIIEVGEGVTRLQVGDNVAIKP 96 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Frame = +2 Query: 275 CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGI 454 C C G + C ++ F G L Y D +LP+ ++ GAL+EPL V Sbjct: 103 CAACLGGWVNCCDNLGFVGFSGSAGGLSDYVVVKEDRAVRLPEGFDLDLGALVEPLTVAW 162 Query: 455 HACKRGGVSAGH--VVLVLGRDP 517 HA R + H LV+G P Sbjct: 163 HAVNRSSIQNDHARTALVVGAGP 185 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 727,777,575 Number of Sequences: 1657284 Number of extensions: 15531264 Number of successful extensions: 48211 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 44707 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 47606 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 51239674196 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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