Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbVm0045
(630 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY312160-1|AAQ82434.1| 1569|Homo sapiens mucin glycoprotein prot... 33 0.83
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 31 2.5
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 31 2.5
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 31 2.5
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 30 5.9
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 30 5.9
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 30 5.9
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 30 5.9
AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3 pr... 30 7.8
AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine recepto... 30 7.8
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 27 8.8
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 27 8.8
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 27 8.8
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 27 8.8
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 27 8.8
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 27 8.8
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 27 8.8
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 27 8.8
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 27 9.3
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 27 9.6
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 27 9.8
>AY312160-1|AAQ82434.1| 1569|Homo sapiens mucin glycoprotein protein.
Length = 1569
Score = 33.1 bits (72), Expect = 0.83
Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Frame = -1
Query: 207 HTFQRVWRDAQCS*-GKQVVAVCMDFFHSSLYHIPKHRTL*RNAC 76
+ F+R W + +CS Q A C HS +YH+P + R+AC
Sbjct: 1049 NAFRRSWAERKCSVINSQTFATC----HSKVYHLPYYEACVRDAC 1089
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 31.5 bits (68), Expect = 2.5
Identities = 26/88 (29%), Positives = 29/88 (32%), Gaps = 2/88 (2%)
Frame = +3
Query: 72 GGMRCVXAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEG 245
G RCV G C D E C Q P C + CAC PA G G
Sbjct: 655 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 710
Query: 246 ATCRFIRRN*AKPPPLCVRSLSNASKEF 329
A C+ + PPP N F
Sbjct: 711 APCQDVDECARSPPPCTYGRCENTEGSF 738
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 31.5 bits (68), Expect = 2.5
Identities = 26/88 (29%), Positives = 29/88 (32%), Gaps = 2/88 (2%)
Frame = +3
Query: 72 GGMRCVXAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEG 245
G RCV G C D E C Q P C + CAC PA G G
Sbjct: 692 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 747
Query: 246 ATCRFIRRN*AKPPPLCVRSLSNASKEF 329
A C+ + PPP N F
Sbjct: 748 APCQDVDECARSPPPCTYGRCENTEGSF 775
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 31.5 bits (68), Expect = 2.5
Identities = 26/88 (29%), Positives = 29/88 (32%), Gaps = 2/88 (2%)
Frame = +3
Query: 72 GGMRCVXAYG--ALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEG 245
G RCV G C D E C Q P C + CAC PA G G
Sbjct: 625 GSFRCVCPAGFRGSACEEDVDE---CAQEPPPCGPGRCDNTAGSFHCAC-PAGFRSRGPG 680
Query: 246 ATCRFIRRN*AKPPPLCVRSLSNASKEF 329
A C+ + PPP N F
Sbjct: 681 APCQDVDECARSPPPCTYGRCENTEGSF 708
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 30.3 bits (65), Expect = 5.9
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = +3
Query: 72 GGMRCVXAYGALVCGTDYCEK-NPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEGA 248
G RC+ G + + CE + C++ P +C T + KC CP +L G
Sbjct: 2125 GSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGR 2182
Query: 249 TCRFIR 266
C+ +R
Sbjct: 2183 RCQDLR 2188
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 30.3 bits (65), Expect = 5.9
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = +3
Query: 72 GGMRCVXAYGALVCGTDYCEK-NPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEGA 248
G RC+ G + + CE + C++ P +C T + KC CP +L G
Sbjct: 1994 GSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGR 2051
Query: 249 TCRFIR 266
C+ +R
Sbjct: 2052 RCQDLR 2057
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 30.3 bits (65), Expect = 5.9
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = +3
Query: 72 GGMRCVXAYGALVCGTDYCEK-NPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEGA 248
G RC+ G + + CE + C++ P +C T + KC CP +L G
Sbjct: 429 GSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGR 486
Query: 249 TCRFIR 266
C+ +R
Sbjct: 487 RCQDLR 492
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 30.3 bits (65), Expect = 5.9
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%)
Frame = +3
Query: 72 GGMRCVXAYGALVCGTDYCEK-NPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEGA 248
G RC+ G + + CE + C++ P +C T + KC CP +L G
Sbjct: 1994 GSYRCICPPGYSL-QNEKCEDIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGR 2051
Query: 249 TCRFIR 266
C+ +R
Sbjct: 2052 RCQDLR 2057
>AJ001515-1|CAA04798.1| 4870|Homo sapiens ryanodine receptor 3
protein.
Length = 4870
Score = 29.9 bits (64), Expect = 7.8
Identities = 25/73 (34%), Positives = 33/73 (45%)
Frame = -1
Query: 246 HLHQVKLHKRDNKHTFQRVWRDAQCS*GKQVVAVCMDFFHSSLYHIPKHRTL*RNACHQH 67
HL QV+ R K VW K+ V C F + LY++P+HR++ N
Sbjct: 3460 HLEQVEQPLRSKK----AVWHKLLSKQRKRAVVAC--FRMAPLYNLPRHRSI--NLFLHG 3511
Query: 66 YKNQRFHFEIFEY 28
Y QRF E EY
Sbjct: 3512 Y--QRFWIETEEY 3522
>AB001025-1|BAA23795.1| 4866|Homo sapiens brain ryanodine receptor
protein.
Length = 4866
Score = 29.9 bits (64), Expect = 7.8
Identities = 25/73 (34%), Positives = 33/73 (45%)
Frame = -1
Query: 246 HLHQVKLHKRDNKHTFQRVWRDAQCS*GKQVVAVCMDFFHSSLYHIPKHRTL*RNACHQH 67
HL QV+ R K VW K+ V C F + LY++P+HR++ N
Sbjct: 3456 HLEQVEQPLRSKK----AVWHKLLSKQRKRAVVAC--FRMAPLYNLPRHRSI--NLFLHG 3507
Query: 66 YKNQRFHFEIFEY 28
Y QRF E EY
Sbjct: 3508 Y--QRFWIETEEY 3518
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 193 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 224
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 160 DFCSANPCV 168
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 27.1 bits (57), Expect(2) = 8.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221
Score = 21.0 bits (42), Expect(2) = 8.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 157 DFCSANPCV 165
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 27.1 bits (57), Expect(2) = 9.3
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 9.3
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 27.1 bits (57), Expect(2) = 9.6
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 21.0 bits (42), Expect(2) = 9.6
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 158 DFCSANPCV 166
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 27.1 bits (57), Expect(2) = 9.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Frame = +3
Query: 126 CEK--NPCIQPPLVCPKNTE-HRARHAGKCAC 212
CE+ N C Q P CPK T H + +C C
Sbjct: 190 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221
Score = 21.0 bits (42), Expect(2) = 9.8
Identities = 5/9 (55%), Positives = 7/9 (77%)
Frame = +3
Query: 120 DYCEKNPCI 146
D+C NPC+
Sbjct: 157 DFCSANPCV 165
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 87,697,873
Number of Sequences: 237096
Number of extensions: 1880549
Number of successful extensions: 3546
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3302
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3543
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6860268620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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