Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbVf0584
(598 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC117211-1|AAI17212.1| 979|Homo sapiens NLRP3 protein protein. 31 4.1
BC063308-1|AAH63308.1| 961|Homo sapiens DDEF2 protein protein. 31 4.1
AY422168-1|AAQ98889.1| 977|Homo sapiens cryopyrin deletion 4 is... 31 4.1
AY051117-1|AAL12497.1| 1034|Homo sapiens cryopyrin protein. 31 4.1
AL606804-11|CAI17155.1| 977|Homo sapiens NLR family, pyrin doma... 31 4.1
AL606804-10|CAI17153.1| 1036|Homo sapiens NLR family, pyrin doma... 31 4.1
AF468522-1|AAL78632.1| 1036|Homo sapiens NALP3 long isoform prot... 31 4.1
AF420469-1|AAL65136.1| 1034|Homo sapiens PYRIN-containing APAF1-... 31 4.1
AF410477-1|AAL33908.1| 1034|Homo sapiens cryopyrin protein. 31 4.1
AC079782-1|AAY14904.1| 328|Homo sapiens unknown protein. 31 4.1
AB007860-1|BAA23696.2| 1022|Homo sapiens KIAA0400 protein. 31 4.1
BC126212-1|AAI26213.1| 547|Homo sapiens beta-carotene 15,15'-mo... 30 5.4
BC126210-1|AAI26211.1| 547|Homo sapiens beta-carotene 15,15'-mo... 30 5.4
BC068529-1|AAH68529.1| 575|Homo sapiens POLL protein protein. 30 5.4
AY302442-1|AAQ74388.1| 483|Homo sapiens DNA polymerase lamda2 p... 30 5.4
AL627424-12|CAI41037.1| 188|Homo sapiens polymerase (DNA direct... 30 5.4
AL627424-11|CAI41036.1| 269|Homo sapiens polymerase (DNA direct... 30 5.4
AL627424-10|CAI41035.1| 470|Homo sapiens polymerase (DNA direct... 30 5.4
AL627424-8|CAI41032.1| 575|Homo sapiens polymerase (DNA directe... 30 5.4
AL627424-6|CAI41031.1| 515|Homo sapiens polymerase (DNA directe... 30 5.4
AK021600-1|BAB13852.1| 515|Homo sapiens protein ( Homo sapiens ... 30 5.4
AK001592-1|BAA91776.1| 547|Homo sapiens protein ( Homo sapiens ... 30 5.4
AJ131890-1|CAB65074.1| 575|Homo sapiens DNA polymerase lambda p... 30 5.4
AF525924-1|AAM77696.1| 575|Homo sapiens polymerase (DNA directe... 30 5.4
AF294900-1|AAG15380.1| 547|Homo sapiens beta, beta-carotene 15,... 30 5.4
AF283478-1|AAG22519.1| 575|Homo sapiens DNA polymerase beta2 pr... 30 5.4
AF161019-1|AAF27541.1| 575|Homo sapiens DNA polymerase lambda p... 30 5.4
BC093825-1|AAH93825.1| 1037|Homo sapiens caspase recruitment dom... 29 9.5
AF356193-1|AAK32718.1| 1037|Homo sapiens caspase recruitment dom... 29 9.5
>BC117211-1|AAI17212.1| 979|Homo sapiens NLRP3 protein protein.
Length = 979
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 762 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 815
Query: 304 RIFC 315
I C
Sbjct: 816 AILC 819
>BC063308-1|AAH63308.1| 961|Homo sapiens DDEF2 protein protein.
Length = 961
Score = 30.7 bits (66), Expect = 4.1
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +3
Query: 27 FFELDWFTTKLTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFD 176
F + FT +LTA +I+N N + F DS+ ++ + + K PFD
Sbjct: 98 FLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFD 147
>AY422168-1|AAQ98889.1| 977|Homo sapiens cryopyrin deletion 4
isoform protein.
Length = 977
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 760 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 813
Query: 304 RIFC 315
I C
Sbjct: 814 AILC 817
>AY051117-1|AAL12497.1| 1034|Homo sapiens cryopyrin protein.
Length = 1034
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 817 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 870
Query: 304 RIFC 315
I C
Sbjct: 871 AILC 874
>AL606804-11|CAI17155.1| 977|Homo sapiens NLR family, pyrin domain
containing 3 protein.
Length = 977
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 760 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 813
Query: 304 RIFC 315
I C
Sbjct: 814 AILC 817
>AL606804-10|CAI17153.1| 1036|Homo sapiens NLR family, pyrin domain
containing 3 protein.
Length = 1036
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 819 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 872
Query: 304 RIFC 315
I C
Sbjct: 873 AILC 876
>AF468522-1|AAL78632.1| 1036|Homo sapiens NALP3 long isoform
protein.
Length = 1036
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 819 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 872
Query: 304 RIFC 315
I C
Sbjct: 873 AILC 876
>AF420469-1|AAL65136.1| 1034|Homo sapiens PYRIN-containing
APAF1-like protein 1 protein.
Length = 1034
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 817 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 870
Query: 304 RIFC 315
I C
Sbjct: 871 AILC 874
>AF410477-1|AAL33908.1| 1034|Homo sapiens cryopyrin protein.
Length = 1034
Score = 30.7 bits (66), Expect = 4.1
Identities = 20/64 (31%), Positives = 29/64 (45%)
Frame = +1
Query: 124 CQ*LKL*RCSTKEKYLLICRKSSVTCLKDSCCLEVLKVDSHSSSCFRLSIRQQRQGLGSF 303
C LK C+ K+ +L+ C CL +CC ++ V S S S RL + + G
Sbjct: 817 CVGLKHLLCNLKKLWLVSC------CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGV 870
Query: 304 RIFC 315
I C
Sbjct: 871 AILC 874
>AC079782-1|AAY14904.1| 328|Homo sapiens unknown protein.
Length = 328
Score = 30.7 bits (66), Expect = 4.1
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +3
Query: 27 FFELDWFTTKLTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFD 176
F + FT +LTA +I+N N + F DS+ ++ + + K PFD
Sbjct: 56 FLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFD 105
>AB007860-1|BAA23696.2| 1022|Homo sapiens KIAA0400 protein.
Length = 1022
Score = 30.7 bits (66), Expect = 4.1
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +3
Query: 27 FFELDWFTTKLTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFD 176
F + FT +LTA +I+N N + F DS+ ++ + + K PFD
Sbjct: 114 FLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFD 163
>BC126212-1|AAI26213.1| 547|Homo sapiens beta-carotene
15,15'-monooxygenase 1 protein.
Length = 547
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +3
Query: 57 LTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFDMSEEFCYMPKRLML 218
L G + + + ++VIFK +P T + + +GK P+ +E FC +P R +L
Sbjct: 182 LNMGTSIVEKGKTKYVIFK---IPAT-VPEGKKQGKSPWKHTEVFCSIPSRSLL 231
>BC126210-1|AAI26211.1| 547|Homo sapiens beta-carotene
15,15'-monooxygenase 1 protein.
Length = 547
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +3
Query: 57 LTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFDMSEEFCYMPKRLML 218
L G + + + ++VIFK +P T + + +GK P+ +E FC +P R +L
Sbjct: 182 LNMGTSIVEKGKTKYVIFK---IPAT-VPEGKKQGKSPWKHTEVFCSIPSRSLL 231
>BC068529-1|AAH68529.1| 575|Homo sapiens POLL protein protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AY302442-1|AAQ74388.1| 483|Homo sapiens DNA polymerase lamda2
protein.
Length = 483
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AL627424-12|CAI41037.1| 188|Homo sapiens polymerase (DNA
directed), lambda protein.
Length = 188
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AL627424-11|CAI41036.1| 269|Homo sapiens polymerase (DNA
directed), lambda protein.
Length = 269
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AL627424-10|CAI41035.1| 470|Homo sapiens polymerase (DNA
directed), lambda protein.
Length = 470
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AL627424-8|CAI41032.1| 575|Homo sapiens polymerase (DNA directed),
lambda protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AL627424-6|CAI41031.1| 515|Homo sapiens polymerase (DNA directed),
lambda protein.
Length = 515
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AK021600-1|BAB13852.1| 515|Homo sapiens protein ( Homo sapiens
cDNA FLJ11538 fis, clone HEMBA1002746, weakly similar to
DNA POLYMERASE BETA (EC 2.7.7.7). ).
Length = 515
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AK001592-1|BAA91776.1| 547|Homo sapiens protein ( Homo sapiens
cDNA FLJ10730 fis, clone NT2RP3001307. ).
Length = 547
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +3
Query: 57 LTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFDMSEEFCYMPKRLML 218
L G + + + ++VIFK +P T + + +GK P+ +E FC +P R +L
Sbjct: 182 LNMGTSIVEKGKTKYVIFK---IPAT-VPEGKKQGKSPWKHTEVFCSIPSRSLL 231
>AJ131890-1|CAB65074.1| 575|Homo sapiens DNA polymerase lambda
protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AF525924-1|AAM77696.1| 575|Homo sapiens polymerase (DNA directed),
lambda protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AF294900-1|AAG15380.1| 547|Homo sapiens beta, beta-carotene
15,15'- dioxygenase protein.
Length = 547
Score = 30.3 bits (65), Expect = 5.4
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +3
Query: 57 LTAGQNKIIRNSNEFVIFKEDSVPMTEIMKMLDEGKVPFDMSEEFCYMPKRLML 218
L G + + + ++VIFK +P T + + +GK P+ +E FC +P R +L
Sbjct: 182 LNMGTSIVEKGKTKYVIFK---IPAT-VPEGKKQGKSPWKHTEVFCSIPSRSLL 231
>AF283478-1|AAG22519.1| 575|Homo sapiens DNA polymerase beta2
protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>AF161019-1|AAF27541.1| 575|Homo sapiens DNA polymerase lambda
protein.
Length = 575
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = -3
Query: 350 DPEGSQEAYCQEQKIRKEPSPCLCCRMDRRKQELEWESTFSTSRQH 213
DP G +A+ + QKI + S + ++ RR++ E E S+ R H
Sbjct: 2 DPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAH 47
>BC093825-1|AAH93825.1| 1037|Homo sapiens caspase recruitment domain
family, member 6 protein.
Length = 1037
Score = 29.5 bits (63), Expect = 9.5
Identities = 12/32 (37%), Positives = 16/32 (50%)
Frame = -3
Query: 380 EP*IMHQQRGDPEGSQEAYCQEQKIRKEPSPC 285
+P H P+ SQ CQ Q + +PSPC
Sbjct: 956 QPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPC 987
>AF356193-1|AAK32718.1| 1037|Homo sapiens caspase recruitment domain
protein 6 protein.
Length = 1037
Score = 29.5 bits (63), Expect = 9.5
Identities = 12/32 (37%), Positives = 16/32 (50%)
Frame = -3
Query: 380 EP*IMHQQRGDPEGSQEAYCQEQKIRKEPSPC 285
+P H P+ SQ CQ Q + +PSPC
Sbjct: 956 QPKPFHSVPSQPKSSQTKSCQSQPSQTKPSPC 987
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,286,206
Number of Sequences: 237096
Number of extensions: 1880538
Number of successful extensions: 8116
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 7994
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8116
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6324506272
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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