BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= fbVf0429 (776 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 122 1e-26 UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decar... 121 2e-26 UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 114 3e-24 UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decar... 97 3e-19 UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 97 3e-19 UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 94 3e-18 UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 94 3e-18 UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 91 2e-17 UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 91 4e-17 UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decar... 90 7e-17 UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 89 9e-17 UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decar... 87 5e-16 UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decar... 86 8e-16 UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 85 2e-15 UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 85 2e-15 UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 84 4e-15 UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 83 8e-15 UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decar... 82 2e-14 UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 81 2e-14 UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 81 3e-14 UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 80 5e-14 UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decar... 80 5e-14 UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putat... 80 5e-14 UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 78 2e-13 UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogen... 77 5e-13 UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 76 1e-12 UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehy... 75 2e-12 UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 74 5e-12 UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putat... 73 8e-12 UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 69 1e-10 UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 7e-10 UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10 UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 65 2e-09 UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 64 4e-09 UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decar... 64 5e-09 UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 63 7e-09 UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 62 1e-08 UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 61 3e-08 UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 61 3e-08 UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 60 5e-08 UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 60 6e-08 UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decar... 58 2e-07 UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ... 58 2e-07 UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 56 7e-07 UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 55 2e-06 UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decar... 54 3e-06 UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 54 3e-06 UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphog... 54 5e-06 UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU008... 54 5e-06 UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 1e-05 UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05 UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole gen... 51 4e-05 UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05 UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 50 9e-05 UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 49 1e-04 UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gamb... 48 3e-04 UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302, w... 47 6e-04 UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 45 0.002 UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gamb... 44 0.003 UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.004 UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; ... 41 0.040 UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 39 0.12 UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, w... 39 0.12 UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, wh... 39 0.12 UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 38 0.21 UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.21 UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.21 UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 38 0.28 UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 37 0.49 UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 37 0.49 UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 36 0.85 UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 36 0.85 UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 36 1.5 UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 36 1.5 UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 36 1.5 UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 35 2.0 UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 35 2.0 UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1; Thermoana... 35 2.6 UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 35 2.6 UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 2.6 UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 35 2.6 UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 3.4 UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 3.4 UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 34 3.4 UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 34 3.4 UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 34 3.4 UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 34 4.6 UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 34 4.6 UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 4.6 UniRef50_A6FXV9 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0 UniRef50_Q5K969 Cluster: Ubiquinone metabolism-related protein, ... 33 6.0 UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 33 8.0 UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 33 8.0 UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 8.0 UniRef50_Q7PZR1 Cluster: ENSANGP00000015639; n=2; Culicidae|Rep:... 33 8.0 UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 33 8.0 UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 33 8.0 UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydia... 33 8.0 >UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=220; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Drosophila melanogaster (Fruit fly) Length = 481 Score = 122 bits (293), Expect = 1e-26 Identities = 55/81 (67%), Positives = 70/81 (86%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SL+DMVSKLK PRK++LLVKAG AVD+F+++L+PLLS GD+IIDGGNS+Y DT + C Sbjct: 56 ADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCD 115 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 EL+ G+L+VG GVSGGE+GA Sbjct: 116 ELAKLGLLFVGSGVSGGEEGA 136 Score = 109 bits (262), Expect = 8e-23 Identities = 50/83 (60%), Positives = 60/83 (72%), Gaps = 1/83 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GPSLMPGGH AAWP I+ IFQAICAKA+ EPCC+WVG+ GAGHFVKMVH + L Sbjct: 138 HGPSLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQL 197 Query: 690 -SATYHLMKDVIGIEQDEMAKVF 755 YH+MK +G+ D+MA F Sbjct: 198 ICEAYHIMKS-LGLSADQMADEF 219 Score = 88.6 bits (210), Expect = 2e-16 Identities = 41/52 (78%), Positives = 49/52 (94%) Frame = +2 Query: 110 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK*LG 265 +ADIALIGLAVMGQNLILNM++KG+VVCA+NRTV+KV+EFL NEAK TK +G Sbjct: 4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIG 55 >UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=91; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Homo sapiens (Human) Length = 483 Score = 121 bits (291), Expect = 2e-26 Identities = 55/81 (67%), Positives = 69/81 (85%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SL +MVSKLK+PR+I+LLVKAG AVD+F++KL+PLL GDIIIDGGNS+Y DT + C+ Sbjct: 55 AQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCR 114 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 +L GIL+VG GVSGGE+GA Sbjct: 115 DLKAKGILFVGSGVSGGEEGA 135 Score = 119 bits (287), Expect = 7e-26 Identities = 55/89 (61%), Positives = 64/89 (71%), Gaps = 2/89 (2%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAK-ANDEPCCDWVGEDGAGHFVKMVHMELNMVICN 686 YGPSLMPGG+ AWPHIK IFQ I AK EPCCDWVG++GAGHFVKMVH + Sbjct: 137 YGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQ 196 Query: 687 L-SATYHLMKDVIGIEQDEMAKVFDE*TK 770 L YHLMKDV+G+ QDEMA+ F++ K Sbjct: 197 LICEAYHLMKDVLGMAQDEMAQAFEDWNK 225 Score = 93.9 bits (223), Expect = 4e-18 Identities = 44/52 (84%), Positives = 49/52 (94%) Frame = +2 Query: 110 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK*LG 265 +ADIALIGLAVMGQNLILNMND G+VVCAFNRTVSKV++FL NEAKGTK +G Sbjct: 3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVG 54 >UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Fungi/Metazoa group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Caenorhabditis elegans Length = 484 Score = 114 bits (274), Expect = 3e-24 Identities = 49/88 (55%), Positives = 62/88 (70%), Gaps = 1/88 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GPSLMPGG+P AWPH+K+IFQ I AK+N EPCCDWVG G+GHFVKMVH + L Sbjct: 137 FGPSLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDWVGNAGSGHFVKMVHNGIEYGDMQL 196 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE*TK 770 A YHL+ + + D+MA+V D+ K Sbjct: 197 IAEAYHLLSKAVELNHDQMAEVLDDWNK 224 Score = 99.1 bits (236), Expect = 1e-19 Identities = 42/81 (51%), Positives = 63/81 (77%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A S+++M KLKRPR++++L+KAG VD + ++P L +GDIIIDGGNS+Y D+ + + Sbjct: 55 AHSIEEMCKKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSE 114 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 +L+ GI++VG GVSGGE+GA Sbjct: 115 QLAAKGIMFVGCGVSGGEEGA 135 Score = 88.2 bits (209), Expect = 2e-16 Identities = 41/52 (78%), Positives = 46/52 (88%) Frame = +2 Query: 110 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK*LG 265 EADIA+IGLAVMGQNLILNMND G+ VCAFNRTV V++FL NEAKGTK +G Sbjct: 3 EADIAVIGLAVMGQNLILNMNDHGFTVCAFNRTVKLVDDFLANEAKGTKIIG 54 >UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Cyanobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechocystis sp. (strain PCC 6803) Length = 482 Score = 97.5 bits (232), Expect = 3e-19 Identities = 45/81 (55%), Positives = 63/81 (77%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A ++++ V L+RPRKI+++VKAG VD + +L PLL +GD+IIDGGNS Y DT++ K Sbjct: 62 AYTVEEFVQLLERPRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTK 121 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 +L TG+ +VGMGVSGGE+GA Sbjct: 122 DLEATGLGFVGMGVSGGEEGA 142 Score = 66.1 bits (154), Expect = 9e-10 Identities = 34/87 (39%), Positives = 52/87 (59%), Gaps = 4/87 (4%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAN--DEPCC-DWVGEDGAGHFVKMVHMELNMVIC 683 GPSLMPGG PAA+ ++ I I A+ D P C ++G GAGH+VKMVH + Sbjct: 145 GPSLMPGGTPAAYKELEPILTKIAAQVEDPDNPACVTFIGPGGAGHYVKMVHNGIEYGDM 204 Query: 684 NLSA-TYHLMKDVIGIEQDEMAKVFDE 761 L A Y ++K+ +G+ +++ +VF + Sbjct: 205 QLIAEAYDILKNGLGLSNEQLHEVFGQ 231 Score = 48.8 bits (111), Expect = 1e-04 Identities = 20/42 (47%), Positives = 30/42 (71%) Frame = +2 Query: 125 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 250 +IGLAVMG+NL LN+ +G+ + FNR+ +K E+F+ A G Sbjct: 15 VIGLAVMGENLALNVESRGFPIAVFNRSPNKTEKFMAERAVG 56 >UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=65; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 471 Score = 97.5 bits (232), Expect = 3e-19 Identities = 45/81 (55%), Positives = 63/81 (77%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SL+D V+ L+RPR+I+++VKAG VD V++L PLL GD+IIDGGNS + DT++ K Sbjct: 55 AYSLEDFVASLERPRRILVMVKAGGPVDAVVEQLKPLLDPGDLIIDGGNSLFTDTERRVK 114 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 +L G+ ++GMGVSGGE+GA Sbjct: 115 DLEALGLGFMGMGVSGGEEGA 135 Score = 72.5 bits (170), Expect = 1e-11 Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNLS 692 GPSLMPGG AA+ ++ I ++I A+ +D PC ++G G+GH+VKMVH + L Sbjct: 138 GPSLMPGGTQAAYEAVEPIVRSIAAQVDDGPCVTYIGPGGSGHYVKMVHNGIEYGDMQLI 197 Query: 693 A-TYHLMKDVIGIEQDEMAKVF 755 A Y L+K V G+ E+ VF Sbjct: 198 AEAYDLLKSVAGLNASELHDVF 219 Score = 48.8 bits (111), Expect = 1e-04 Identities = 21/42 (50%), Positives = 29/42 (69%) Frame = +2 Query: 125 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 250 LIGLAVMG+NL LN+ G+ + +NRT K E F+ + A+G Sbjct: 8 LIGLAVMGENLALNIERNGFSLTVYNRTAEKTEAFMADRAQG 49 >UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Lactobacillus|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Lactobacillus acidophilus Length = 467 Score = 94.3 bits (224), Expect = 3e-18 Identities = 42/79 (53%), Positives = 60/79 (75%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +L++ V+ L++PRKI++ + AG VD+ + KL+PLL KGDI+IDGGNS Y DT + E+ Sbjct: 53 TLEEFVNSLEKPRKILIQIMAGDPVDQTLHKLLPLLDKGDIVIDGGNSNYHDTNRRYHEM 112 Query: 451 SGTGILYVGMGVSGGEDGA 507 GI ++GMGVSGGE+GA Sbjct: 113 EKHGIHFIGMGVSGGEEGA 131 Score = 75.4 bits (177), Expect = 2e-12 Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVIC-N 686 GP+LMPGG A+ + I +AI AK D +PC ++G +GAGH+VKMVH + I Sbjct: 134 GPALMPGGDEEAYKEVAPILEAIAAKNKDGKPCVSYMGPEGAGHYVKMVHNGIEYAIMQE 193 Query: 687 LSATYHLMKDVIGIEQDEMAKVFDE 761 S Y L++DV EM+++FD+ Sbjct: 194 FSEVYSLLRDVAHKSNGEMSEIFDK 218 Score = 33.1 bits (72), Expect = 8.0 Identities = 15/39 (38%), Positives = 25/39 (64%) Frame = +2 Query: 125 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 241 +IGL+VMG+NL LN+ + G+ V ++ +V+ K E Sbjct: 6 VIGLSVMGKNLALNVRNHGFSVSGYSIDKPEVDALAKYE 44 >UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating 2; n=27; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating 2 - Bacillus subtilis Length = 469 Score = 94.3 bits (224), Expect = 3e-18 Identities = 43/79 (54%), Positives = 60/79 (75%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 S+++ V L+ PRKI+L+VKAG A D ++ L+P L K DI+IDGGN+ Y DTQ+ KEL Sbjct: 56 SIEEFVQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKEL 115 Query: 451 SGTGILYVGMGVSGGEDGA 507 + +GI ++G GVSGGE+GA Sbjct: 116 AESGIHFIGTGVSGGEEGA 134 Score = 83.4 bits (197), Expect = 6e-15 Identities = 40/87 (45%), Positives = 55/87 (63%), Gaps = 1/87 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL- 689 GPS+MPGG A +K I +AI AK + EPC ++G DGAGH+VKMVH + L Sbjct: 137 GPSIMPGGQKEAHELVKPILEAISAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLI 196 Query: 690 SATYHLMKDVIGIEQDEMAKVFDE*TK 770 S +Y ++K V+G+ DE+ +VF E K Sbjct: 197 SESYFILKQVLGLSADELHEVFAEWNK 223 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/53 (50%), Positives = 38/53 (71%) Frame = +2 Query: 107 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK*LG 265 ++ I +IGLAVMG+NL LN+ +G+ V +NR+ SK EEFL+ EAKG +G Sbjct: 2 SKQQIGVIGLAVMGKNLALNIESRGFSVSVYNRSSSKTEEFLQ-EAKGKNVVG 53 >UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Myxococcus xanthus (strain DK 1622) Length = 474 Score = 91.5 bits (217), Expect = 2e-17 Identities = 39/79 (49%), Positives = 63/79 (79%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL+ V +L+RPRK++L+V AG AVD +++L+PL+++GD+I+D GNS +LDT++ ++ Sbjct: 59 SLEAFVQRLERPRKVLLMVTAGAAVDSMLERLLPLMAEGDVIMDAGNSWFLDTRRREEQC 118 Query: 451 SGTGILYVGMGVSGGEDGA 507 GI ++G+GVSGGE+GA Sbjct: 119 KAKGIHFLGVGVSGGEEGA 137 Score = 78.2 bits (184), Expect = 2e-13 Identities = 35/84 (41%), Positives = 54/84 (64%), Gaps = 1/84 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNLS 692 GPS+MPGG P+A+ ++ +F+AI A + PC +VG DGAGHFVKMVH + L Sbjct: 140 GPSIMPGGAPSAYELVRPVFEAIAANTDMGPCVTYVGADGAGHFVKMVHNGIEYADMQLL 199 Query: 693 A-TYHLMKDVIGIEQDEMAKVFDE 761 A TY +++ +G++ D +A + + Sbjct: 200 AETYDVLRRGLGLDADALADLLSQ 223 >UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Enterococcus faecalis (Streptococcus faecalis) Length = 473 Score = 90.6 bits (215), Expect = 4e-17 Identities = 39/79 (49%), Positives = 63/79 (79%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 S+++ V+ +++PR+I+L+VKAG A D +++L+P L KGDI+IDGGN+ + DT + +EL Sbjct: 56 SIEEFVNAIEKPRRIMLMVKAGPATDATIQELLPHLDKGDILIDGGNTFFKDTMRRNEEL 115 Query: 451 SGTGILYVGMGVSGGEDGA 507 + +GI ++G GVSGGE+GA Sbjct: 116 ANSGINFIGTGVSGGEEGA 134 Score = 82.2 bits (194), Expect = 1e-14 Identities = 40/85 (47%), Positives = 55/85 (64%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPS+MPGG A+ + I + I AKA D EPC ++G +GAGH+VKMVH + L Sbjct: 137 GPSIMPGGQKEAYELVAPILEKISAKAEDGEPCVTYIGPNGAGHYVKMVHNGIEYGDMQL 196 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE 761 A +Y LMK ++G+ DEMA++F E Sbjct: 197 IAESYDLMKQILGLSVDEMAEIFKE 221 Score = 44.4 bits (100), Expect = 0.003 Identities = 18/37 (48%), Positives = 27/37 (72%) Frame = +2 Query: 125 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 ++G+AVMG+NL LN+ +GY V +NRT SK E ++ Sbjct: 8 VVGMAVMGKNLALNIESRGYTVALYNRTGSKTTEVVE 44 >UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Cyanidioschyzon merolae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cyanidioschyzon merolae (Red alga) Length = 640 Score = 89.8 bits (213), Expect = 7e-17 Identities = 43/78 (55%), Positives = 55/78 (70%) Frame = +1 Query: 274 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 453 L V LKRPR++ LLVKAG AVD V+ L +L GDII+DGGN Y +T++ ++ Sbjct: 163 LRSFVLSLKRPRRVFLLVKAGSAVDATVEALAEVLEPGDIIVDGGNEWYENTERRAASVA 222 Query: 454 GTGILYVGMGVSGGEDGA 507 G+LYVGMGVSGGE+GA Sbjct: 223 ARGLLYVGMGVSGGEEGA 240 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 2/84 (2%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKA-NDEPCCDWVGEDGAGHFVKMVHMELNMVICN 686 YGPSLMPGG A+ + + + + A+ PC ++G G+G++VKMVH + Sbjct: 242 YGPSLMPGGSREAYQQLAPLLEQVAAQVPGSGPCVTYIGPGGSGNYVKMVHNGIEYGDMQ 301 Query: 687 L-SATYHLMKDVIGIEQDEMAKVF 755 L Y L++ +G++ A+VF Sbjct: 302 LIGEAYDLLRGAVGLDAMAAAEVF 325 Score = 41.1 bits (92), Expect = 0.030 Identities = 18/38 (47%), Positives = 25/38 (65%) Frame = +2 Query: 113 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 226 +D +IGLAVMGQN LN+ G+ V +NRT ++ E Sbjct: 100 SDAGVIGLAVMGQNFALNLASHGWRVSVYNRTYARTAE 137 >UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=10; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Bacteroides fragilis Length = 491 Score = 89.4 bits (212), Expect = 9e-17 Identities = 41/80 (51%), Positives = 55/80 (68%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 T ++ V + PRKI+++V+AG VDE +++L P LS GDI+IDGGNS Y DT + K Sbjct: 64 TDIEAFVESIALPRKIMMMVRAGSPVDELMEQLFPYLSPGDILIDGGNSNYEDTNRRVKL 123 Query: 448 LSGTGILYVGMGVSGGEDGA 507 G L+VG GVSGGE+GA Sbjct: 124 AESKGFLFVGAGVSGGEEGA 143 Score = 82.2 bits (194), Expect = 1e-14 Identities = 39/83 (46%), Positives = 52/83 (62%), Gaps = 2/83 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 G S+MPGG AW +K I Q+I A+A D PCC WVG G+GHFVKM+H + L Sbjct: 146 GASIMPGGSEKAWEEVKPILQSIAAQAPDGTPCCQWVGPAGSGHFVKMIHNGIEYGDMQL 205 Query: 690 SA-TYHLMKDVIGIEQDEMAKVF 755 A Y +MK+++ + +EMA VF Sbjct: 206 IAEAYWVMKELLDMTNEEMASVF 228 Score = 57.6 bits (133), Expect = 3e-07 Identities = 30/54 (55%), Positives = 36/54 (66%), Gaps = 5/54 (9%) Frame = +2 Query: 104 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE-----FLKNEAKG 250 QN+ DI LIGLAVMG+NL LNM +G+ V +NRTV VEE F+ AKG Sbjct: 4 QNKTDIGLIGLAVMGENLALNMESRGWNVSVYNRTVPGVEEGVVERFINGRAKG 57 >UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=17; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 468 Score = 87.0 bits (206), Expect = 5e-16 Identities = 42/79 (53%), Positives = 57/79 (72%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL++ V L++PRKI+L+VKAG A D + L+PLL DI+IDGGN+ Y DT + K L Sbjct: 55 SLEEFVESLEKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKAL 114 Query: 451 SGTGILYVGMGVSGGEDGA 507 + + I ++GMGVSGGE GA Sbjct: 115 AESSINFIGMGVSGGEIGA 133 Score = 75.8 bits (178), Expect = 1e-12 Identities = 37/85 (43%), Positives = 53/85 (62%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPSLMPGG A+ + +I AI AKA D C ++G +GAGH+VKMVH + L Sbjct: 136 GPSLMPGGQKDAYNKVSDILDAIAAKAQDGASCVTYIGPNGAGHYVKMVHNGIEYADMQL 195 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE 761 A +Y +MKD++G+ E+++ F E Sbjct: 196 IAESYAMMKDLLGMSHKEISQTFKE 220 Score = 43.6 bits (98), Expect = 0.006 Identities = 18/39 (46%), Positives = 27/39 (69%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 I ++GLAVMG+NL N+ +GY V +NR+ K +E +K Sbjct: 5 IGVVGLAVMGKNLAWNIESRGYSVSVYNRSRQKTDEMVK 43 >UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteroidetes|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 627 Score = 86.2 bits (204), Expect = 8e-16 Identities = 38/78 (48%), Positives = 56/78 (71%) Frame = +1 Query: 274 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 453 L + L++PRKI L++KAG D F+++L+P L+ GD++IDGGNS Y DT++ + L+ Sbjct: 225 LKTFAASLEQPRKIFLMIKAGEETDTFIEELVPYLNAGDVLIDGGNSYYGDTKRRIEFLA 284 Query: 454 GTGILYVGMGVSGGEDGA 507 GI ++G GVSGGE GA Sbjct: 285 RKGIYFIGTGVSGGEQGA 302 Score = 67.7 bits (158), Expect = 3e-10 Identities = 34/85 (40%), Positives = 49/85 (57%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPS+MP G P A+ +++ I AK E CC ++G+DG+GHFVKM+H + L Sbjct: 305 GPSIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTYIGKDGSGHFVKMIHNGIEYAEMQL 364 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE 761 A Y ++ I IE E+A +F E Sbjct: 365 IAEVYAYLRYAIKIEPTEIAALFTE 389 >UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; unidentified eubacterium SCB49|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - unidentified eubacterium SCB49 Length = 628 Score = 84.6 bits (200), Expect = 2e-15 Identities = 42/84 (50%), Positives = 59/84 (70%), Gaps = 3/84 (3%) Frame = +1 Query: 265 ATSLDDM---VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQK 435 A + DD+ V+ L++PRKI+L+V AG +D ++ L+P LSK DI+IDGGNS YL T++ Sbjct: 219 AAAFDDISAFVNSLQQPRKIMLMVNAGKTIDFVIEDLLPHLSKNDILIDGGNSNYLKTKE 278 Query: 436 WCKELSGTGILYVGMGVSGGEDGA 507 L GI ++G GVSGGE+GA Sbjct: 279 RFDYLKDKGIHFIGTGVSGGEEGA 302 Score = 64.1 bits (149), Expect = 4e-09 Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 1/83 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAK-ANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPS+MP G A+ +K + I AK N PCC +VG +G+GHF+KMVH + V L Sbjct: 305 GPSIMPSGAAEAYEDVKPFLETIAAKDQNGLPCCTYVGTEGSGHFIKMVHNGIEYVEMQL 364 Query: 690 SATYHLMKDVIGIEQDEMAKVFD 758 A + G DE+A + + Sbjct: 365 LAEVCSVLKHAGKNLDEIADILE 387 Score = 38.3 bits (85), Expect = 0.21 Identities = 17/38 (44%), Positives = 24/38 (63%) Frame = +2 Query: 113 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 226 +D L GL VMG++L N+ + G+ + FNR V VEE Sbjct: 166 SDFGLFGLGVMGKSLCRNLANNGFKISMFNRHVDGVEE 203 >UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=5; Plasmodium|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Plasmodium vivax Length = 473 Score = 84.6 bits (200), Expect = 2e-15 Identities = 39/79 (49%), Positives = 56/79 (70%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +L+ +++ LK+PRKI+LL+KAG AVDE +K ++ +GDIIIDGGN YL+T++ Sbjct: 59 TLEQLINNLKKPRKIILLIKAGPAVDETIKNILKHFEEGDIIIDGGNEWYLNTERRITLC 118 Query: 451 SGTGILYVGMGVSGGEDGA 507 + Y+ MGVSGGE GA Sbjct: 119 EEHKVEYLAMGVSGGEAGA 137 Score = 62.5 bits (145), Expect = 1e-08 Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 YG S MPGG A+ IK+I + AK PC ++G +G++VKMVH + L Sbjct: 139 YGCSFMPGGSKYAYDTIKDILEKCSAKVGTSPCVTYIGPRSSGNYVKMVHNGIEYGDMQL 198 Query: 690 -SATYHLMKDVIGIEQDEMAKVF 755 S +Y LMK+++ +++++VF Sbjct: 199 ISESYLLMKNILNYNNEKLSEVF 221 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/45 (51%), Positives = 30/45 (66%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 250 DI LIGLAVMGQNL LN+ G+ + +NRT + E+ LK +G Sbjct: 6 DIGLIGLAVMGQNLSLNIASNGFTIGVYNRTYERTEDTLKKAKEG 50 >UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=292; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Escherichia coli Length = 468 Score = 83.8 bits (198), Expect = 4e-15 Identities = 39/79 (49%), Positives = 54/79 (68%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 ++ + V L+ PR+I+L+VKAG D + L P L KGDIIIDGGN+ + DT + +EL Sbjct: 56 TVQEFVESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNREL 115 Query: 451 SGTGILYVGMGVSGGEDGA 507 S G ++G GVSGGE+GA Sbjct: 116 SAEGFNFIGTGVSGGEEGA 134 Score = 70.1 bits (164), Expect = 6e-11 Identities = 36/85 (42%), Positives = 50/85 (58%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPS+MPGG A+ + I + I A A D EPC ++G DGAGH+VKMVH + L Sbjct: 137 GPSIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQL 196 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE 761 A Y L+K + + +E+A+ F E Sbjct: 197 IAEAYALLKGGLTLSNEELAQTFTE 221 Score = 46.8 bits (106), Expect = 6e-04 Identities = 19/42 (45%), Positives = 29/42 (69%) Frame = +2 Query: 107 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 ++ I ++G+AVMG+NL LN+ +GY V FNR+ K EE + Sbjct: 2 SKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVI 43 >UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Borrelia burgdorferi group|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Borrelia garinii Length = 464 Score = 83.0 bits (196), Expect = 8e-15 Identities = 40/78 (51%), Positives = 57/78 (73%) Frame = +1 Query: 274 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 453 ++ V LK PRKI+L+V + AV++ V++++PLL+K DIIIDGGNS Y +T + KEL Sbjct: 54 VESFVKSLKPPRKIILMVTS-LAVEKVVEQILPLLNKSDIIIDGGNSHYKNTMRIEKELF 112 Query: 454 GTGILYVGMGVSGGEDGA 507 I +VG+G+SGGE GA Sbjct: 113 AKDIYFVGLGISGGERGA 130 Score = 64.1 bits (149), Expect = 4e-09 Identities = 30/90 (33%), Positives = 53/90 (58%), Gaps = 2/90 (2%) Frame = +3 Query: 498 RWCTYGPSLMPGGHPAAWPHIKEIFQAICAKA-NDEPCCDWVGEDGAGHFVKMVHMELNM 674 R +GP+LM GG +A+ ++ I I AK N++ C ++GE+G+GH+VKM+H + Sbjct: 128 RGARFGPALMYGGSKSAYEILEPILNKIAAKTKNNDVCSTYIGENGSGHYVKMIHNGVEY 187 Query: 675 VICNL-SATYHLMKDVIGIEQDEMAKVFDE 761 L S Y MK ++ ++++VF++ Sbjct: 188 ADMQLISEVYFFMKKAFNLDNSKISEVFEK 217 Score = 43.2 bits (97), Expect = 0.007 Identities = 19/43 (44%), Positives = 26/43 (60%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 D+ + GL VMG NL LN+ D G+ V +NR K E F+K + Sbjct: 2 DVGIYGLGVMGGNLALNIADNGFNVSVYNRDSEKTEIFVKQNS 44 >UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Trichomonas vaginalis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trichomonas vaginalis G3 Length = 489 Score = 81.8 bits (193), Expect = 2e-14 Identities = 39/83 (46%), Positives = 53/83 (63%), Gaps = 2/83 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDE-PCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPS+M GGH W + K + I AKA D+ PC D++G DGAGHFVKMVH + L Sbjct: 134 GPSMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDYMGTDGAGHFVKMVHNAIEYADMQL 193 Query: 690 SA-TYHLMKDVIGIEQDEMAKVF 755 A TYH+M++ + I +++A VF Sbjct: 194 IAETYHIMRNSLQISNEDIADVF 216 Score = 80.2 bits (189), Expect = 5e-14 Identities = 37/79 (46%), Positives = 58/79 (73%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +++++V LK+PR +++V A F VD +++L LL K D+IIDGGNS + DT++ K + Sbjct: 54 TIEEVVEALKKPRIFLIIVTAEF-VDNVIEQLKVLLEKDDVIIDGGNSHWPDTERRQKAI 112 Query: 451 SGTGILYVGMGVSGGEDGA 507 TG+ +VGMG+SGGE+GA Sbjct: 113 EPTGVHFVGMGISGGEEGA 131 Score = 39.1 bits (87), Expect = 0.12 Identities = 17/40 (42%), Positives = 23/40 (57%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 D+ + GL MG N+ N G+ V AFNRT ++ E LK Sbjct: 4 DLCVFGLGTMGSNIARNFAHHGFKVAAFNRTWARTEALLK 43 >UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=25; Alphaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Rhizobium meliloti (Sinorhizobium meliloti) Length = 476 Score = 81.4 bits (192), Expect = 2e-14 Identities = 34/79 (43%), Positives = 58/79 (73%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 ++++ V+ ++ PR I++++KAG VD+ ++ L P L+KGDI+ID GN+ + DT + L Sbjct: 58 TIEEFVAAIRPPRPIIIMIKAGDPVDQQMEALKPHLAKGDIMIDAGNANFRDTMRRFDAL 117 Query: 451 SGTGILYVGMGVSGGEDGA 507 +G+ ++GMGVSGGE+GA Sbjct: 118 KDSGLTFIGMGVSGGEEGA 136 Score = 66.9 bits (156), Expect = 5e-10 Identities = 28/83 (33%), Positives = 51/83 (61%), Gaps = 1/83 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GPS+M GG ++ ++++ +I AK + +PC W+GE+GAGHFVK +H + + Sbjct: 138 HGPSIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAWLGENGAGHFVKTIHNGIEYADMQM 197 Query: 690 SA-TYHLMKDVIGIEQDEMAKVF 755 A Y +++D + + E+ +VF Sbjct: 198 IAEIYGILRDGLKMTAQEIGEVF 220 Score = 47.2 bits (107), Expect = 5e-04 Identities = 21/41 (51%), Positives = 28/41 (68%) Frame = +2 Query: 107 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF 229 ++A+I LIGL VMG NL LN+ +KG + FNRTV +F Sbjct: 2 SQAEIGLIGLGVMGSNLALNIAEKGNRIAVFNRTVDATRKF 42 >UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 481 Score = 81.0 bits (191), Expect = 3e-14 Identities = 33/84 (39%), Positives = 52/84 (61%), Gaps = 1/84 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GPS+MPGG AW ++ + +A AK +EPC DW+G AGH+VKMVH + + L Sbjct: 147 HGPSMMPGGDSTAWERLRPMLEAAAAKVGEEPCVDWLGRGSAGHYVKMVHNGIEYSLMQL 206 Query: 690 -SATYHLMKDVIGIEQDEMAKVFD 758 S +Y LM +G+ ++M +++ Sbjct: 207 ISESYDLMYRGLGLSHEKMHPIYE 230 Score = 74.9 bits (176), Expect = 2e-12 Identities = 36/78 (46%), Positives = 52/78 (66%) Frame = +1 Query: 274 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 453 + ++ L++PR I+LLV AG VD ++ L P L +G I+IDGGNS + DT + + L+ Sbjct: 68 IQPFIASLRQPRLILLLVPAGDPVDGVIQDLSPDLEQGTILIDGGNSHFRDTDRRIQTLA 127 Query: 454 GTGILYVGMGVSGGEDGA 507 + +VGMGVSGGE GA Sbjct: 128 QQNVHFVGMGVSGGEAGA 145 Score = 37.9 bits (84), Expect = 0.28 Identities = 17/35 (48%), Positives = 24/35 (68%) Frame = +2 Query: 113 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK 217 ADI +IGL VMG NL LN+ ++G+ V ++R K Sbjct: 10 ADIGIIGLGVMGANLGLNIAEQGFNVAGYDRNPEK 44 >UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Bacillus halodurans Length = 298 Score = 80.2 bits (189), Expect = 5e-14 Identities = 38/81 (46%), Positives = 53/81 (65%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SL+++VSKL PRKI ++V AG + V +L LL +GD++IDGGN+ Y DT + K Sbjct: 47 ADSLEELVSKLSAPRKIWVMVPAGDITENVVSQLSSLLDEGDVVIDGGNANYKDTLRRAK 106 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 + G+ +V G SGG DGA Sbjct: 107 QYEAKGLHFVDAGTSGGIDGA 127 >UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=2; Bacillaceae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oceanobacillus iheyensis Length = 465 Score = 80.2 bits (189), Expect = 5e-14 Identities = 36/78 (46%), Positives = 53/78 (67%) Frame = +1 Query: 274 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 453 L+ V+ L++PRK+ L+V AG +D + L+PLL K DI++DGGNS + D+ + L Sbjct: 55 LERFVNSLEKPRKVFLMVTAGPVIDSVIDSLVPLLDKDDIMMDGGNSNFNDSNRRYHRLK 114 Query: 454 GTGILYVGMGVSGGEDGA 507 GI +V +GVSGGE+GA Sbjct: 115 EAGIHFVSVGVSGGEEGA 132 Score = 66.1 bits (154), Expect = 9e-10 Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 1/85 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GP+LMP G + + I + I A+ + + CC ++G++G+GH+VKMVH + L Sbjct: 134 HGPALMPSGDEKVYQEVAPILEKIAAQVDGKACCGYLGKEGSGHYVKMVHNGIEYADMQL 193 Query: 690 -SATYHLMKDVIGIEQDEMAKVFDE 761 + Y +++ +G+ +E+A F E Sbjct: 194 ITEAYQFLRERLGLSVEEIATTFRE 218 Score = 38.3 bits (85), Expect = 0.21 Identities = 18/40 (45%), Positives = 23/40 (57%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN 238 I + GL VMG NL +NM +KG V +N T E+F N Sbjct: 4 IGVFGLGVMGANLAMNMANKGEKVAVYNYTSDLTEKFKSN 43 >UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putative; n=2; Theileria|Rep: 6-phosphogluconate dehydrogenase, putative - Theileria annulata Length = 443 Score = 80.2 bits (189), Expect = 5e-14 Identities = 38/79 (48%), Positives = 53/79 (67%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +L++ V L RPR I++L+ AG AVD + KLIPLL + D+++DGGN Y +T++ Sbjct: 73 NLEEFVLSLNRPRMILILIIAGEAVDCVLDKLIPLLDRDDLVVDGGNEWYNNTERRILRC 132 Query: 451 SGTGILYVGMGVSGGEDGA 507 GI Y GMG+SGGE GA Sbjct: 133 KEEGIRYSGMGISGGERGA 151 >UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=21; Actinobacteria (class)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium bovis Length = 685 Score = 78.2 bits (184), Expect = 2e-13 Identities = 33/79 (41%), Positives = 55/79 (69%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 ++ + ++ L++PR+++++VKAG A D + +L + GDIIIDGGN+ Y DT + K + Sbjct: 44 TIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAM 103 Query: 451 SGTGILYVGMGVSGGEDGA 507 G+ +VG G+SGGE+GA Sbjct: 104 RERGLHFVGAGISGGEEGA 122 Score = 69.7 bits (163), Expect = 7e-11 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL- 689 GPS+MPGG ++ + + + I A + PCC +G DG+GHFVKMVH + L Sbjct: 125 GPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLI 184 Query: 690 SATYHLMKDVIGIEQDEMAKVFDE 761 Y LM+D +G+ +A VF E Sbjct: 185 GEAYQLMRDGLGLTAPAIADVFTE 208 >UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogenase; n=1; Prototheca wickerhamii|Rep: Plastid 6-phosphogluconate 2-dehydrogenase - Prototheca wickerhamii Length = 507 Score = 77.0 bits (181), Expect = 5e-13 Identities = 40/77 (51%), Positives = 53/77 (68%), Gaps = 1/77 (1%) Frame = +1 Query: 280 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIP-LLSKGDIIIDGGNSQYLDTQKWCKELSG 456 D V LKRPR+I++LVKAG VD K+L ++ DIIIDGGN Y +T++ EL+ Sbjct: 215 DFVLSLKRPRRIIILVKAGAPVDSTSKQLTEFVVEPRDIIIDGGNEWYENTERRQAELAT 274 Query: 457 TGILYVGMGVSGGEDGA 507 G ++GMGVSGGE+GA Sbjct: 275 KGSHHIGMGVSGGEEGA 291 Score = 68.5 bits (160), Expect = 2e-10 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 1/84 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNLS 692 GP++MPGG A+ H++ + + + A+ +D C ++G GAG++VKMVH + L Sbjct: 294 GPAMMPGGDKGAYSHLRPVVEKVAAQTDDGACVTYIGPGGAGNYVKMVHNGIEYGDMQLI 353 Query: 693 A-TYHLMKDVIGIEQDEMAKVFDE 761 A Y ++K V G+ E+A VF E Sbjct: 354 AEAYDVLKTVGGLTNAELASVFSE 377 >UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=43; Trypanosomatidae|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Trypanosoma brucei brucei Length = 479 Score = 75.8 bits (178), Expect = 1e-12 Identities = 31/79 (39%), Positives = 54/79 (68%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +++ + LK+PRK ++LV+AG A D ++L + KGDI++D GN+ + D + ++L Sbjct: 59 TMEAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQL 118 Query: 451 SGTGILYVGMGVSGGEDGA 507 G+ ++GMG+SGGE+GA Sbjct: 119 EAAGLRFLGMGISGGEEGA 137 Score = 55.2 bits (127), Expect = 2e-06 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 1/84 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GP+ PGG + W I+ I +A AKA+D PC G GAG VKM H I + Sbjct: 140 GPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQI 199 Query: 690 SATYHLMKDVIGIEQDEMAKVFDE 761 + +G+ DE+A V ++ Sbjct: 200 WGEVFDILRAMGLNNDEVAAVLED 223 Score = 54.8 bits (126), Expect = 2e-06 Identities = 24/43 (55%), Positives = 31/43 (72%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 D+ ++GL VMG NL LN+ +KG+ V FNRT SK EEF+K A Sbjct: 4 DVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANA 46 >UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehydrogenase; n=1; Brevibacterium linens BL2|Rep: COG0362: 6-phosphogluconate dehydrogenase - Brevibacterium linens BL2 Length = 511 Score = 74.9 bits (176), Expect = 2e-12 Identities = 36/81 (44%), Positives = 51/81 (62%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A+S D+ SKL PR +L+V AG A D + L+ + GD+I+DGGNS + DT + Sbjct: 58 ASSPADLASKLSGPRVAILMVNAGAATDSAINDLVEVFEPGDVIVDGGNSLFTDTIARGE 117 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 + GI +VG+G+SGGE GA Sbjct: 118 TVRQAGIEFVGVGISGGEVGA 138 Score = 52.4 bits (120), Expect = 1e-05 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 23/106 (21%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKA----------------------NDEPCCDWVGE 626 GPS+M GG +AW ++ I + I A+A + E C VG Sbjct: 141 GPSMMVGGTESAWSRLRPILEPIAARAATGDARAESSDGNGAPADRAEIDQESCIAHVGT 200 Query: 627 DGAGHFVKMVHMELNMVICNLSA-TYHLMKDVIGIEQDEMAKVFDE 761 DGAGHFVKM+H + L A + L++ +G+ E+A+VF E Sbjct: 201 DGAGHFVKMIHNGIEYADMQLIAEAFALLRSRLGLTPSEIAEVFRE 246 >UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 488 Score = 74.9 bits (176), Expect = 2e-12 Identities = 35/81 (43%), Positives = 57/81 (70%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A++L+D V+ L+ PR +++V+AG + D +++L L+ +GDII+D GNS + DT + K Sbjct: 62 ASTLEDFVASLRAPRVAIMMVQAGPSTDAVMEQLADLMDEGDIIVDCGNSLFTDTIRREK 121 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 + G+ +VG GVSGGE+GA Sbjct: 122 WAAERGLHFVGAGVSGGEEGA 142 Score = 74.9 bits (176), Expect = 2e-12 Identities = 33/83 (39%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GPS+MPGG PA++ + +F+AI + PCC ++G +GAGHFVKMVH + + Sbjct: 144 WGPSIMPGGTPASYDRLGPMFEAIAGTYDGVPCCTYIGANGAGHFVKMVHNGIEYADMQV 203 Query: 690 SA-TYHLMKDVIGIEQDEMAKVF 755 A Y L+++ +G E+A +F Sbjct: 204 IAEAYTLLREGLGATPAEIADIF 226 Score = 41.5 bits (93), Expect = 0.023 Identities = 18/40 (45%), Positives = 24/40 (60%) Frame = +2 Query: 113 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 ADI + GL VMG NL N+ GY FNRT ++ E+ + Sbjct: 11 ADIGVYGLGVMGANLARNLARNGYATAVFNRTPARTEKLM 50 >UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=30; cellular organisms|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium leprae Length = 486 Score = 73.7 bits (173), Expect = 5e-12 Identities = 32/79 (40%), Positives = 54/79 (68%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 ++ + ++ L+ PR+++++VKAG A D + +L ++ DIIIDGGNS + DT + K + Sbjct: 67 TIPEFLAALQTPRRVLIMVKAGDATDAVINELADVMEPSDIIIDGGNSLFTDTIRREKAM 126 Query: 451 SGTGILYVGMGVSGGEDGA 507 G+ +VG G+SGGE+GA Sbjct: 127 RERGLHFVGAGISGGEEGA 145 Score = 63.7 bits (148), Expect = 5e-09 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL- 689 GPS+MPGG ++ + + + I A + CC +G G+GHFVKMVH + L Sbjct: 148 GPSIMPGGPAESYTSLGPLLEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYSDMQLI 207 Query: 690 SATYHLMKDVIGIEQDEMAKVFDE 761 Y L++D +G+ ++A VF E Sbjct: 208 GEAYQLLRDGLGMSAPQIADVFTE 231 Score = 39.9 bits (89), Expect = 0.069 Identities = 18/41 (43%), Positives = 24/41 (58%) Frame = +2 Query: 113 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 A I + GLAVMG N+ N GY V NR+++K + LK Sbjct: 14 AQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDTLLK 54 >UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putative; n=1; Babesia bovis|Rep: 6-phosphogluconate dehydrogenase, putative - Babesia bovis Length = 453 Score = 72.9 bits (171), Expect = 8e-12 Identities = 35/82 (42%), Positives = 52/82 (63%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 T+ + + L++PRKI++LV AG AVD+ + ++ LL GDI+IDGGN Y +T + Sbjct: 53 TNFGEYIESLEKPRKILMLVTAGKAVDQVLNCILGLLEVGDIVIDGGNEWYENTIGRIER 112 Query: 448 LSGTGILYVGMGVSGGEDGAHM 513 G+ + MGVSGGE GA + Sbjct: 113 CKQKGVHFCAMGVSGGERGARI 134 Score = 36.3 bits (80), Expect = 0.85 Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Frame = +3 Query: 615 WVGEDGAGHFVKMVHMELNMVICN-LSATYHLMKDVIGIEQDEMAKVFDE 761 +VG +GH+VKMVH + + LS Y +M +++ +E D + + E Sbjct: 162 YVGPGASGHYVKMVHNGIEYAMMQALSEIYMIMSNILELELDTIGNILGE 211 >UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=8; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Marinomonas sp. MWYL1 Length = 507 Score = 68.9 bits (161), Expect = 1e-10 Identities = 34/102 (33%), Positives = 59/102 (57%), Gaps = 18/102 (17%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKAND-----------------EPCCDWVGEDGAG 638 +GPSLMPGG +W +++ +++A+ AK ++ EPC ++G +GAG Sbjct: 148 FGPSLMPGGDADSWKYLQPMWEAVAAKVDENGKPIESNTPGKPVTEGEPCTAYLGPNGAG 207 Query: 639 HFVKMVHMELNMVICNL-SATYHLMKDVIGIEQDEMAKVFDE 761 H+VKMVH + L YHL++ ++G E +E+ K+F++ Sbjct: 208 HYVKMVHNGIEYADMQLICEAYHLLRSLLGYEPEEIGKLFEK 249 Score = 56.4 bits (130), Expect = 7e-07 Identities = 34/81 (41%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 444 ++++DM++ L +PR IV+LV AG VD LI L DI++D GNSQ+ DT + Sbjct: 67 SNMEDMLANLVKPRVIVVLVPAGSPVDAVCNSLIDAGLEADDIVVDCGNSQWTDTIRREA 126 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 E + G VSGGE GA Sbjct: 127 EYK-EKFKFFGTAVSGGEVGA 146 Score = 42.7 bits (96), Expect = 0.010 Identities = 21/49 (42%), Positives = 29/49 (59%) Frame = +2 Query: 95 KMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 241 K QN +I +GL VMG+NL LN+ D GY V F+ K+++ L E Sbjct: 3 KTNQN-CNIGFVGLGVMGKNLALNLADHGYRVAGFDLDAHKIQDVLDTE 50 >UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Acidobacteria bacterium (strain Ellin345) Length = 211 Score = 66.5 bits (155), Expect = 7e-10 Identities = 37/74 (50%), Positives = 47/74 (63%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SL D+V KLK PR + L+V AG AVD +L+ L GD +IDGGNS Y+D + + Sbjct: 93 AASLGDVVEKLKPPRAVWLMVPAG-AVDGTAVELLDFLEPGDTLIDGGNSYYVDDIRRAR 151 Query: 445 ELSGTGILYVGMGV 486 EL+ GI YV GV Sbjct: 152 ELALRGIHYVDEGV 165 >UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 329 Score = 66.1 bits (154), Expect = 9e-10 Identities = 32/85 (37%), Positives = 52/85 (61%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDWVGEDGAGHFVKMVHMEL-NMVICN 686 GPS+ PGG A + + + I AKA+D PC +G+ GAGH+VKM+H + + ++ Sbjct: 149 GPSMCPGGQEQALDIVMPLLEKIAAKASDGTPCVARIGDGGAGHYVKMIHNGIEHGMMSA 208 Query: 687 LSATYHLMKDVIGIEQDEMAKVFDE 761 +S + M +G+E DE+ KVF++ Sbjct: 209 ISEAWTFMNKHLGMEYDEIGKVFEK 233 >UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; Encephalitozoon cuniculi|Rep: 6-PHOSPHOGLUCONATE DEHYDROGENASE - Encephalitozoon cuniculi Length = 458 Score = 64.9 bits (151), Expect = 2e-09 Identities = 35/80 (43%), Positives = 53/80 (66%), Gaps = 1/80 (1%) Frame = +1 Query: 271 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 S++D+V +K PR I+L++ +G VD F+++L L K D++IDGGNS Y DT + + Sbjct: 57 SVEDLVVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRRNRY 116 Query: 448 LSGTGILYVGMGVSGGEDGA 507 G +VG G+SGGE+GA Sbjct: 117 KFG----FVGCGISGGEEGA 132 Score = 60.9 bits (141), Expect = 3e-08 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 3/86 (3%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAK--ANDEPCCDWVGEDGAGHFVKMVHMELNM-VI 680 YGPS+M G +W ++ I A + + CC W+GE GAGHFVKMVH + + Sbjct: 134 YGPSIMVGCDKDSWEKVQGFLTDISAVEVSGSKRCCVWLGEGGAGHFVKMVHNGIEYGDM 193 Query: 681 CNLSATYHLMKDVIGIEQDEMAKVFD 758 +S TY ++K +G+ E++ +FD Sbjct: 194 AIISETYLVLKS-LGLSNMEISSLFD 218 Score = 45.6 bits (103), Expect = 0.001 Identities = 22/47 (46%), Positives = 32/47 (68%), Gaps = 1/47 (2%) Frame = +2 Query: 98 MPQN-EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 MPQ + +I LIGL VMG +L LN+ +GY + FNRT SK ++ ++ Sbjct: 1 MPQTPKMEIGLIGLGVMGHSLALNIVSRGYRLHVFNRTSSKTDDLVR 47 >UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Rhodopseudomonas palustris Length = 346 Score = 64.1 bits (149), Expect = 4e-09 Identities = 31/77 (40%), Positives = 48/77 (62%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A L+D+V KL PR + +++ AG + +++L LL+ GD++IDGGN+ + D + K Sbjct: 47 AGGLEDLVRKLDAPRAVWVMLPAGQITETTIEQLAKLLAAGDVVIDGGNTFWQDDIRRAK 106 Query: 445 ELSGTGILYVGMGVSGG 495 L T I YV +G SGG Sbjct: 107 TLKETSIDYVDVGTSGG 123 >UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Oryza sativa (indica cultivar-group)|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Oryza sativa subsp. indica (Rice) Length = 446 Score = 63.7 bits (148), Expect = 5e-09 Identities = 34/88 (38%), Positives = 51/88 (57%), Gaps = 2/88 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDE-PCCDWVGEDGAGHFVKMVHMELNMVICNL 689 GPSLMPGG A+ +I++I + A+ D PC ++G+ G+G+FVKMVH + L Sbjct: 96 GPSLMPGGSFEAYKYIEDILLKVAAQVPDSGPCVTYIGKGGSGNFVKMVHNGIEYGDMQL 155 Query: 690 -SATYHLMKDVIGIEQDEMAKVFDE*TK 770 S Y ++K V + E+ +VF E K Sbjct: 156 ISEAYDVLKSVGKLTNSELQQVFSEWNK 183 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/45 (55%), Positives = 33/45 (73%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 253 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E ++ AK T Sbjct: 6 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVQG-AKHT 49 >UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2; n=11; root|Rep: 6-phosphogluconate dehydrogenase, decarboxylating Gnd2 - Mycobacterium ulcerans (strain Agy99) Length = 360 Score = 63.3 bits (147), Expect = 7e-09 Identities = 37/89 (41%), Positives = 50/89 (56%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 +SL ++ KL PR I ++V AG +++L L GDI+IDGGN+ Y D K K Sbjct: 69 SSLSELRDKLSAPRVIWVMVPAGTITTGVIEELATTLDAGDIVIDGGNTYYRDDIKHAKL 128 Query: 448 LSGTGILYVGMGVSGGEDGAHMDHL*CLV 534 LSG GI + G SGG G +D CL+ Sbjct: 129 LSGKGIHMLDCGTSGGVWG--LDRGYCLM 155 >UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bacteria|Rep: Uncharacterized protein yqeC - Bacillus subtilis Length = 297 Score = 62.5 bits (145), Expect = 1e-08 Identities = 32/80 (40%), Positives = 50/80 (62%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 T+L + +S L PR + ++V G VD ++ + PLLSKGD+II+ GNS Y ++ + + Sbjct: 48 TNLKEFISLLHPPRILWVMVPHGI-VDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQ 106 Query: 448 LSGTGILYVGMGVSGGEDGA 507 + GI Y+ G SGG +GA Sbjct: 107 MKEAGIHYLDAGTSGGMEGA 126 Score = 33.9 bits (74), Expect = 4.6 Identities = 17/50 (34%), Positives = 26/50 (52%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVH 659 +G M GG AW ++ +F+ E + GE G+GHF+KM+H Sbjct: 128 HGACFMVGGDHEAWEIVEPLFRDTAV----ENGYLYAGEAGSGHFLKMIH 173 >UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; Actinobacteria (class)|Rep: Phosphogluconate dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 303 Score = 60.9 bits (141), Expect = 3e-08 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 4/85 (4%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL ++ +L+ PR + ++V AG + V +L +L GD++IDGGNS+Y D + + L Sbjct: 40 SLAELARRLESPRVVWVMVPAGKITQDTVTELSSVLETGDLVIDGGNSRYTDDKVHGELL 99 Query: 451 SGTGILYVGMGVSGG----EDGAHM 513 GI Y+ GVSGG EDG M Sbjct: 100 GSRGIGYLDCGVSGGVWGLEDGYGM 124 >UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; Alteromonadales|Rep: 6-phosphogluconate dehydrogenase - Alteromonadales bacterium TW-7 Length = 457 Score = 60.9 bits (141), Expect = 3e-08 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNL 689 +GP++M G W I+ F+ + A N C VG+ +GHFVKMVH + + L Sbjct: 137 HGPAMMASGSEGGWERIEPWFEKVAASYNGSSCFARVGQSASGHFVKMVHNGIEYALMQL 196 Query: 690 SA-TYHLMKDVIGIEQDEMAKVFDE 761 A Y L++ E+A +FDE Sbjct: 197 IAEMYQLLRSGTNRSPKEVAAIFDE 221 Score = 51.6 bits (118), Expect = 2e-05 Identities = 34/83 (40%), Positives = 47/83 (56%), Gaps = 3/83 (3%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLD--TQKW 438 + L DMV +L+ PR I+LLV AG VD +L+ + DII+D GNS Y D T+K Sbjct: 56 SDLGDMVRRLEAPRSILLLVPAGELVDTVCNELVNAGVECDDIIVDCGNSNYKDGITRKL 115 Query: 439 CKELSGTGILYVGMGVSGGEDGA 507 + + MG+SGG +GA Sbjct: 116 KYQ---NKFEFATMGISGGAEGA 135 Score = 39.9 bits (89), Expect = 0.069 Identities = 17/38 (44%), Positives = 26/38 (68%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 +AL+GL VMG+NL LN+ DKG + A+++ EE + Sbjct: 3 VALVGLGVMGKNLALNLIDKGITLVAYDKNPHAGEELI 40 >UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative 6-phosphogluconate dehydrogenase - Uncultured methanogenic archaeon RC-I Length = 310 Score = 60.5 bits (140), Expect = 5e-08 Identities = 30/81 (37%), Positives = 47/81 (58%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A + ++ L+ PR I L + AG +D+ ++ LIP L +GD+++DGGNS + D+ + Sbjct: 45 ADTYEEFARLLRTPRIIYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVAREE 104 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 L G + G SGG DGA Sbjct: 105 ALRKKGFRLLDCGTSGGVDGA 125 >UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; Aquifex aeolicus|Rep: 6-phosphogluconate dehydrogenase - Aquifex aeolicus Length = 300 Score = 60.1 bits (139), Expect = 6e-08 Identities = 29/62 (46%), Positives = 41/62 (66%) Frame = +1 Query: 310 KIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVS 489 K V L+ AVDE ++ L P L+KGD +IDGGNS Y D+Q+ +EL + ++ +GVS Sbjct: 62 KTVWLMVPHTAVDEVLQNLKPFLNKGDTVIDGGNSYYKDSQRRYRELKEVDVNFLDVGVS 121 Query: 490 GG 495 GG Sbjct: 122 GG 123 Score = 34.3 bits (75), Expect = 3.4 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICN-L 689 G S M GG + +++F+ + A +E ++G GAGHF KMVH + I + Sbjct: 130 GFSFMIGGDEEVFKKHEKLFKDL---AYEEKGYAYLGSSGAGHFAKMVHNGIEYGIMEAI 186 Query: 690 SATYHLM-KDVIGIEQDEMAKVFDE 761 + + L+ K + E+A+V+ + Sbjct: 187 AEGFELLKKSPFDYDLREVARVYSQ 211 >UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=3; Gammaproteobacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Shewanella sediminis HAW-EB3 Length = 517 Score = 58.0 bits (134), Expect = 2e-07 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 19/102 (18%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDE------------------PCCDWVGEDGA 635 +GPSLMP G AW IK I++AI AK + E PC ++G G+ Sbjct: 151 FGPSLMPSGDIKAWGRIKPIWEAIAAKVDPETGLPIERQEPGNPVTEGEPCTTYIGPVGS 210 Query: 636 GHFVKMVHMELNMVICNL-SATYHLMKDVIGIEQDEMAKVFD 758 GH+VKMVH + L Y L+ D G+ E+ +F+ Sbjct: 211 GHYVKMVHNGIEYADMQLICEAYQLLSDGFGMSASEVGSLFE 252 Score = 47.6 bits (108), Expect = 3e-04 Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWCK 444 ++L +M+S L++PR ++L V AG VD LI + DI+ID GNS + DT + + Sbjct: 70 SNLSEMLSILEKPRVLILSVPAGSPVDGVCNALIEAGIDHDDIVIDTGNSLWTDTVE-RE 128 Query: 445 ELSGTGILYVGMGVSGGEDGA 507 + + VSGGE GA Sbjct: 129 ARYASQFTFFSCAVSGGEMGA 149 Score = 42.3 bits (95), Expect = 0.013 Identities = 19/42 (45%), Positives = 27/42 (64%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE 241 D+ +IGL VMG+NL LN+ D Y V AF+ K+E ++ E Sbjct: 9 DVGVIGLGVMGKNLSLNIADNRYRVAAFDLDTDKIEGLVQQE 50 >UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ATCC 50803|Rep: GLP_26_8052_6637 - Giardia lamblia ATCC 50803 Length = 471 Score = 58.0 bits (134), Expect = 2e-07 Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQY-LDTQKWCKE 447 S+ D V+ L +PR IVLLV+A AVD + + + + DIIID GNS Y L ++ + Sbjct: 53 SVSDFVASLVKPRVIVLLVQAD-AVDSVGEMMAKCMQEDDIIIDSGNSYYKLTEERKVRF 111 Query: 448 LSGTGILYVGMGVSGGEDGA 507 + + G+G+SGGE+GA Sbjct: 112 HKNFKVHFYGIGISGGEEGA 131 Score = 41.9 bits (94), Expect = 0.017 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 7/89 (7%) Frame = +3 Query: 510 YGPSLMPGG-HPAAWPHIKEIFQAICAKANDE-----PCCDWVGEDGAGHFVKMVHMELN 671 +GP++M GG +A + + + +CA E C + G GAGH VKMVH Sbjct: 133 WGPAIMVGGDEESARKRLLPLLEKVCADPQVEGTDGKKCISYCGPGGAGHMVKMVHNGCE 192 Query: 672 MVICNL-SATYHLMKDVIGIEQDEMAKVF 755 I L S + + V+ +++A VF Sbjct: 193 YGIMQLISEAIAIFRSVLKFSVEQVADVF 221 Score = 38.3 bits (85), Expect = 0.21 Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 3/46 (6%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK---VEEFLKNEA 244 DI ++GL MG+NL LN + + V +NRT SK V + LK+E+ Sbjct: 2 DIGIVGLGAMGKNLALNFHRNKFKVAIYNRTHSKAKAVADELKSES 47 >UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12; Firmicutes|Rep: 6-phosphogluconate dehydrogenase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 302 Score = 56.4 bits (130), Expect = 7e-07 Identities = 28/80 (35%), Positives = 49/80 (61%) Frame = +1 Query: 268 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 +++++++++L + + L++ AG + ++ L LS GDI+IDGGNS Y D + K Sbjct: 51 STIENLLTELPASKIVWLMLPAGTPTNSTIEMLSEKLSAGDILIDGGNSNYKDNLEQNKL 110 Query: 448 LSGTGILYVGMGVSGGEDGA 507 L+ GI + +G SGG GA Sbjct: 111 LTEKGIKFFDVGTSGGMAGA 130 >UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24; Bacteria|Rep: 6-phosphogluconate dehydrogenase - Deinococcus radiodurans Length = 368 Score = 55.2 bits (127), Expect = 2e-06 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 2/78 (2%) Frame = +1 Query: 268 TSLDDMVSKLKRP--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWC 441 + +D + L P R + ++V AG + L LS GD+IIDGGNS + DTQ+ Sbjct: 53 SDMDRFIELLGEPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRG 112 Query: 442 KELSGTGILYVGMGVSGG 495 + L+ G+ +V +G SGG Sbjct: 113 EALAAKGLHFVDVGTSGG 130 >UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Nosema bombycis|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Nosema bombycis Length = 457 Score = 54.4 bits (125), Expect = 3e-06 Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Frame = +1 Query: 271 SLDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 447 +++D+V L P+ I++L+ G A+D +K+L L++ DI+ID GNS Y DT + E Sbjct: 51 TVEDLVKCLPNDPKIIMVLLTTGDAIDLMLKELSNFLNETDIVIDLGNSYYKDTIRRNNE 110 Query: 448 LSGTGILYVGMGVSGGEDGA 507 +VG G+SGGE GA Sbjct: 111 FK---FQFVGAGISGGEFGA 127 Score = 53.6 bits (123), Expect = 5e-06 Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 2/52 (3%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIF--QAICAKANDEPCCDWVGEDGAGHFVKMVH 659 YG S+M G W I++I ++ +K ++ CC W GE+G+GHFVKMVH Sbjct: 129 YGASIMVGCATDVWSKIEKILFDLSVTSKFTNKKCCGWFGENGSGHFVKMVH 180 Score = 48.4 bits (110), Expect = 2e-04 Identities = 21/40 (52%), Positives = 28/40 (70%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK 235 +I LIG+ MG+ L LN+NDKGY + +NRT SK E +K Sbjct: 2 EIGLIGIGNMGRELALNINDKGYKLHVYNRTTSKTENLVK 41 >UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase - Haloquadratum walsbyi Length = 306 Score = 54.4 bits (125), Expect = 3e-06 Identities = 31/83 (37%), Positives = 48/83 (57%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 444 A SLD ++ L +++ L+V AG AVD + +L P L++ DII+DGGNS + + + + Sbjct: 47 ADSLDTLLDTLGETKRLWLMVPAGEAVDATLTQLEPSLTETDIIVDGGNSHFEASIRRAE 106 Query: 445 ELSGTGILYVGMGVSGGEDGAHM 513 T Y+ G SGG GA + Sbjct: 107 TSDAT---YLDCGTSGGPAGAEL 126 Score = 35.5 bits (78), Expect = 1.5 Identities = 20/49 (40%), Positives = 27/49 (55%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVH 659 G SLM GG A+ + +F AI + D +G G+GH+VKMVH Sbjct: 127 GFSLMIGGQQWAYDELIPVFDAIATGPDGH---DRMGPVGSGHYVKMVH 172 >UniRef50_UPI00005A38F3 Cluster: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to 6-phosphogluconate dehydrogenase, decarboxylating - Canis familiaris Length = 437 Score = 53.6 bits (123), Expect = 5e-06 Identities = 26/52 (50%), Positives = 36/52 (69%), Gaps = 1/52 (1%) Frame = +3 Query: 618 VGEDGAGHFVKMVHMELNMVICNLSA-TYHLMKDVIGIEQDEMAKVFDE*TK 770 VG++GAGHFVKMVH + L YHLM+DV+G+E ++MA+V +E K Sbjct: 48 VGDEGAGHFVKMVHDGIEYGDMQLICEAYHLMEDVLGMEHNKMAEVLEEWNK 99 >UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU00837.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU00837.1 - Neurospora crassa Length = 488 Score = 53.6 bits (123), Expect = 5e-06 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKAN-DEPCCDWVGEDGAGHFVKMVHMEL-NMVIC 683 +GPS+ PGG A + Q I AK N PC +G G GH+VKM+H + + ++ Sbjct: 126 HGPSISPGGSKEALDKVFPFLQKIAAKDNRGRPCVAKLGPGGCGHYVKMIHNGIEHGMMT 185 Query: 684 NLSATYHLMKDVIGIEQDEMAKVFDE 761 L + +M +G++ +E+ +F++ Sbjct: 186 ALCEAWAIMNIGLGMDYEEIGTIFEK 211 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/79 (34%), Positives = 40/79 (50%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL + + +P+ + + G D+ + L P L GDII+D N + T++ L Sbjct: 46 SLCEALEDGDKPKVFMFSIPHGGPADDSIDALEPYLKPGDIIMDASNEHWKATERRQARL 105 Query: 451 SGTGILYVGMGVSGGEDGA 507 GI Y+GMGVSGG A Sbjct: 106 EPKGIHYIGMGVSGGYQSA 124 >UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate dehydrogenase, decarboxylating - Mycobacterium sp. (strain JLS) Length = 297 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/75 (33%), Positives = 42/75 (56%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL + L PR + ++V +G + + L +L +GD++IDGGNS++ + + L Sbjct: 40 SLAALADALAAPRVVWVMVPSGPVTHDTIVSLAEVLGEGDLVIDGGNSRFTEDAPHAELL 99 Query: 451 SGTGILYVGMGVSGG 495 GI ++ GVSGG Sbjct: 100 KAKGIGFIDAGVSGG 114 >UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 508 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/54 (42%), Positives = 35/54 (64%) Frame = +1 Query: 346 DEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGA 507 DE ++ L+P L + DII+D GN + +T++ ++ TGI Y+G GVSGG A Sbjct: 71 DEVLQGLMPHLERDDIILDCGNEHFANTERRQHKVKDTGIRYIGCGVSGGYQAA 124 Score = 48.8 bits (111), Expect = 1e-04 Identities = 21/50 (42%), Positives = 32/50 (64%), Gaps = 1/50 (2%) Frame = +3 Query: 513 GPSLMPGGHPAAWPHIKEIFQAICAKAN-DEPCCDWVGEDGAGHFVKMVH 659 GPS+ PGG +A + + + + AK ++PC VG+ G+GH+VKMVH Sbjct: 127 GPSMCPGGDRSALNEVLPLLEKVAAKDKIEKPCVGIVGKGGSGHYVKMVH 176 >UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_132, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 142 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/38 (60%), Positives = 29/38 (76%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E L Sbjct: 9 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETL 46 >UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1; Oryza sativa (indica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 200 Score = 50.0 bits (114), Expect = 6e-05 Identities = 22/36 (61%), Positives = 28/36 (77%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 226 I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E Sbjct: 109 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDE 144 >UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family protein; n=16; Bacteria|Rep: 6-phosphogluconate dehydrogenase family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 299 Score = 49.6 bits (113), Expect = 9e-05 Identities = 26/79 (32%), Positives = 42/79 (53%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 SL +++ L + + I L AG ++ V +L+ L+ DII+D GNS + D+ + Sbjct: 49 SLSELLKALNKRKVIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLA 108 Query: 451 SGTGILYVGMGVSGGEDGA 507 GI ++ G SGG GA Sbjct: 109 KEKGIYFIDCGTSGGIKGA 127 >UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding - Chloroflexus aurantiacus J-10-fl Length = 289 Score = 48.8 bits (111), Expect = 1e-04 Identities = 28/75 (37%), Positives = 42/75 (56%) Frame = +1 Query: 313 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 492 ++L++ AV E + +L PLL +G +IID G+S +Q L+ GI +V VSG Sbjct: 57 LILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116 Query: 493 GEDGAHMDHL*CLVG 537 G +GA L +VG Sbjct: 117 GPEGAAAGTLAIMVG 131 >UniRef50_Q7QH45 Cluster: ENSANGP00000020243; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000020243 - Anopheles gambiae str. PEST Length = 99 Score = 47.6 bits (108), Expect = 3e-04 Identities = 27/63 (42%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Frame = +3 Query: 573 QAICAKANDEPCCDWVGEDGAGHFVKMVHMELNM-VICNLSATYHLMKDVIGIEQDEMAK 749 +AICAK+N +P C+ + GAG VKMVH + I + A HLM +G+ + EMA+ Sbjct: 13 EAICAKSNGDPYCEGIVIGGAGDLVKMVHNGIEYGDIQLICAACHLML-ALGMTRKEMAQ 71 Query: 750 VFD 758 FD Sbjct: 72 EFD 74 >UniRef50_A7R0B1 Cluster: Chromosome undetermined scaffold_302, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_302, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 501 Score = 46.8 bits (106), Expect = 6e-04 Identities = 20/51 (39%), Positives = 34/51 (66%), Gaps = 1/51 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKA-NDEPCCDWVGEDGAGHFVKMVH 659 +GPSLM GG A+ ++++ + A+ N PC ++G+ G+G+FVKMV+ Sbjct: 66 HGPSLMLGGSFEAYKYVEDTLLKVAAQVPNSGPCVTYIGKGGSGNFVKMVY 116 >UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1; Streptococcus pneumoniae SP11-BS70|Rep: 6-phosphogluconate dehydrogenase - Streptococcus pneumoniae SP11-BS70 Length = 96 Score = 45.2 bits (102), Expect = 0.002 Identities = 17/41 (41%), Positives = 29/41 (70%) Frame = +2 Query: 110 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 +A+ ++G+AVMG+NL LN+ +GY V +NR+ K E+ + Sbjct: 3 KANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVI 43 >UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000030787 - Anopheles gambiae str. PEST Length = 49 Score = 44.4 bits (100), Expect = 0.003 Identities = 17/28 (60%), Positives = 22/28 (78%) Frame = +3 Query: 558 IKEIFQAICAKANDEPCCDWVGEDGAGH 641 +KE+F AICAK+N PCC+ +G GAGH Sbjct: 1 MKEMFPAICAKSNGNPCCERIGICGAGH 28 >UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; delta proteobacterium MLMS-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - delta proteobacterium MLMS-1 Length = 178 Score = 44.0 bits (99), Expect = 0.004 Identities = 19/47 (40%), Positives = 33/47 (70%) Frame = +1 Query: 265 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDG 405 A S+ ++V KL PR + L++ AG VD+ +++L LLS GD++++G Sbjct: 92 AFSVKELVGKLAAPRVVWLMLPAGETVDQHLEELAELLSPGDLVVEG 138 Score = 34.7 bits (76), Expect = 2.6 Identities = 17/47 (36%), Positives = 25/47 (53%) Frame = +2 Query: 104 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 + I +IGL MG N+ + G+ V AFNR+ +K EE + A Sbjct: 43 EKRMQIGMIGLGRMGMNMARRLLQGGHQVVAFNRSPAKSEELAQEGA 89 >UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 40.7 bits (91), Expect = 0.040 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC-CDWVGEDGAGHFVKMVHMELNMV 677 +GPSLMPGG +I++I A+ +D ++G G+G F+KMV+ L V Sbjct: 33 HGPSLMPGGSSKTHRYIEDILLERAAQVSDNSSGVTYIGRGGSGIFIKMVYDALRPV 89 >UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate dehydrogenase related enzyme - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 287 Score = 39.1 bits (87), Expect = 0.12 Identities = 20/43 (46%), Positives = 23/43 (53%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 +I IG VMG +I N+ GY V FNRT SK L N A Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGA 44 >UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_607, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 209 Score = 39.1 bits (87), Expect = 0.12 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC-CDWVGEDGAGHFVKMVHMELNMVICN 686 +GPSL PGG A +I++I A+ +D ++G G+G+F+KM H + Sbjct: 29 HGPSLTPGGSSKAHKNIEDILLKRAAQVSDNSFGVTYIGRGGSGNFIKM-HSPIKKATAE 87 Query: 687 LSATY 701 L Y Sbjct: 88 LGPFY 92 Score = 37.9 bits (84), Expect = 0.28 Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Frame = +3 Query: 510 YGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC-CDWVGEDGAGHFVKM-VHMELNMVIC 683 +GPSL PGG A HI++I A+ +D ++G G+ +F+KM EL Sbjct: 106 HGPSLTPGGSSKAHKHIEDILLKRAAQVSDNSFGVTYIGRGGSRNFIKMGTGGEL----- 160 Query: 684 NLSATYHLMKDVIGIEQDE 740 LS + D+ GI+ D+ Sbjct: 161 -LSFLVRITIDIFGIKDDK 178 >UniRef50_A7Q584 Cluster: Chromosome undetermined scaffold_52, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome undetermined scaffold_52, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 154 Score = 39.1 bits (87), Expect = 0.12 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +3 Query: 528 PGGHPAAWPHIKEIFQAICAKANDEPCCDWVGEDGAGHFVKMVHMELNMVICNLSA-TYH 704 P G A+ +I++I + +++ PC ++ + G+G+FVKMVH + L A Y Sbjct: 76 PIGSFEAYKYIEDILKVTAQVSDNGPCATYIDKRGSGNFVKMVHNGIEYGDIQLIAKAYD 135 Query: 705 LMKDVIG 725 ++K + G Sbjct: 136 VLKSIGG 142 >UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1; Janthinobacterium sp. Marseille|Rep: 2-hydroxy-3-oxopropionate reductase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 304 Score = 38.3 bits (85), Expect = 0.21 Identities = 19/75 (25%), Positives = 40/75 (53%) Frame = +1 Query: 313 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 492 ++ +++AG V + + +P L G ++ID +++ + Q+ +L+ G+ ++ VSG Sbjct: 67 VITMLEAGPIVAQVIDAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126 Query: 493 GEDGAHMDHL*CLVG 537 G GA L + G Sbjct: 127 GVVGAEAGSLAIMAG 141 Score = 33.9 bits (74), Expect = 4.6 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 226 IA +G+ +MG+ + + GY V A+NRT SK +E Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADE 45 >UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Clostridium beijerinckii NCIMB 8052 Length = 291 Score = 38.3 bits (85), Expect = 0.21 Identities = 17/43 (39%), Positives = 26/43 (60%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 I IG+ VMG++++ N+ KGY V + RT KV + + AK Sbjct: 4 IGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAK 46 >UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Caldivirga maquilingensis IC-167 Length = 295 Score = 38.3 bits (85), Expect = 0.21 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF 229 ++ LIGL MG + N+ D G ++ FNRT+SK +F Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKF 40 >UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16; cellular organisms|Rep: Gamma hydroxybutyrate dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 289 Score = 37.9 bits (84), Expect = 0.28 Identities = 14/43 (32%), Positives = 29/43 (67%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 ++ +GL +MG+ + +N+ G+ V +NRT+SK +E +++ A Sbjct: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 >UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to 3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis Length = 512 Score = 37.1 bits (82), Expect = 0.49 Identities = 16/52 (30%), Positives = 28/52 (53%) Frame = +2 Query: 92 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 K + + +GL +MG ++ N+ + G+ V +NRT K +FLK A+ Sbjct: 220 KNIRASSLKFGFLGLGIMGSGIVKNLLNSGHKVVVWNRTQEKCADFLKAGAE 271 >UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; Candidatus Carsonella ruddii PV|Rep: 6-phosphogluconate dehydrogenase - Carsonella ruddii (strain PV) Length = 433 Score = 37.1 bits (82), Expect = 0.49 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +1 Query: 271 SLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 450 +L ++ + I++L+K G V + + L+ DI+ID GNS + +T + Sbjct: 52 NLKKFINSFSNYKIIIILIKPGLPVKNILFLIKDKLNISDILIDFGNSYFKNTYFNFLNI 111 Query: 451 SGTGILYVGMGVSGGEDGA 507 ++ G+SGG +GA Sbjct: 112 K-KKFSFISAGISGGSEGA 129 >UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase precursor; n=7; Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 36.3 bits (80), Expect = 0.85 Identities = 19/54 (35%), Positives = 31/54 (57%) Frame = +1 Query: 376 LSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAHMDHL*CLVG 537 LSKG I++D + + T+ + K+++ G Y+ VSGG+ GA L +VG Sbjct: 86 LSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTIMVG 139 >UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr11 scaffold_13, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 348 Score = 36.3 bits (80), Expect = 0.85 Identities = 15/38 (39%), Positives = 23/38 (60%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 + IG VMG+++ ++ GY V FNRT+SK + L Sbjct: 51 VGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLL 88 >UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein; n=1; Bos taurus|Rep: PREDICTED: hypothetical protein - Bos taurus Length = 351 Score = 35.5 bits (78), Expect = 1.5 Identities = 14/43 (32%), Positives = 25/43 (58%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 I +GL +MG ++ N+ G+ V +NRT K + F++ A+ Sbjct: 20 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 62 >UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 321 Score = 35.5 bits (78), Expect = 1.5 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 IA IG+ +MG++++ N+ GY + ++RT +K E+ + A Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGA 79 >UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46; Euteleostomi|Rep: Cytokine-like nuclear factor n-pac - Homo sapiens (Human) Length = 553 Score = 35.5 bits (78), Expect = 1.5 Identities = 14/43 (32%), Positives = 25/43 (58%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 I +GL +MG ++ N+ G+ V +NRT K + F++ A+ Sbjct: 270 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 312 >UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15; Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase - Geobacillus kaustophilus Length = 288 Score = 35.1 bits (77), Expect = 2.0 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 I IGL VMG+++ ++ GY + A+ RT K E+ L+ A Sbjct: 4 IGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGA 45 >UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: Oxidoreductase - Sulfolobus solfataricus Length = 289 Score = 35.1 bits (77), Expect = 2.0 Identities = 16/43 (37%), Positives = 24/43 (55%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 + IGL +MG + N+ GY + +NRT+ K E+ K AK Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAK 45 >UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1; Thermoanaerobacter ethanolicus X514|Rep: Glutamyl-tRNA reductase - Thermoanaerobacter ethanolicus X514 Length = 395 Score = 34.7 bits (76), Expect = 2.6 Identities = 18/34 (52%), Positives = 21/34 (61%) Frame = +2 Query: 125 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 226 +IGL MGQN + N+ DKG V NRT SK E Sbjct: 183 VIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIE 216 >UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate dehydrogenase family protein - Roseobacter sp. MED193 Length = 300 Score = 34.7 bits (76), Expect = 2.6 Identities = 20/75 (26%), Positives = 35/75 (46%) Frame = +1 Query: 313 IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 492 ++L + V +++L P L KG I++D S+ T++ G ++ VSG Sbjct: 73 VILSLPKAAIVSAVMEELGPYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132 Query: 493 GEDGAHMDHL*CLVG 537 G GA + +VG Sbjct: 133 GPLGARTGTMTMVVG 147 >UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Mycobacterium sp. (strain KMS) Length = 305 Score = 34.7 bits (76), Expect = 2.6 Identities = 18/45 (40%), Positives = 29/45 (64%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG 250 ++ IGL VMG+ + ++ D G+ V FNR+ +KV+E EA+G Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDEL---EARG 43 >UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2; Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase - Methanosarcina acetivorans Length = 300 Score = 34.7 bits (76), Expect = 2.6 Identities = 14/42 (33%), Positives = 24/42 (57%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 + +IGL +MG + N+ +GY V +NRT K + ++ A Sbjct: 12 VGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGA 53 >UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 292 Score = 34.3 bits (75), Expect = 3.4 Identities = 14/40 (35%), Positives = 26/40 (65%) Frame = +2 Query: 104 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVE 223 +N +A++G+ VMG + N+ +G+ V A+NRT +K + Sbjct: 7 RNATTVAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKAD 46 >UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6; Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 309 Score = 34.3 bits (75), Expect = 3.4 Identities = 16/45 (35%), Positives = 23/45 (51%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 253 + IGL +MG+ + N+ GY + NRT K EEF + T Sbjct: 17 VGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGART 61 >UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase family protein; n=11; Francisella tularensis|Rep: 3-hydroxyisobutyrate dehydrogenase family protein - Francisella tularensis subsp. mediasiatica Length = 295 Score = 34.3 bits (75), Expect = 3.4 Identities = 16/47 (34%), Positives = 27/47 (57%) Frame = +2 Query: 98 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN 238 M + + +IGL MG +I ++ GY + NRT +K E++L+N Sbjct: 1 MAKMSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRN 47 >UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family protein; n=14; Cyanobacteria|Rep: Hydroxyacid dehydrogenase/reductase family protein - Synechococcus sp. (strain WH7803) Length = 302 Score = 34.3 bits (75), Expect = 3.4 Identities = 17/56 (30%), Positives = 29/56 (51%) Frame = +1 Query: 370 PLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGAHMDHL*CLVG 537 P L++G ++ID +Q+ + L+ G+ Y+ V+GG +GA L L G Sbjct: 97 PALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTVLCG 152 >UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate dehydrogenase-like protein - Oryza sativa subsp. japonica (Rice) Length = 293 Score = 34.3 bits (75), Expect = 3.4 Identities = 13/39 (33%), Positives = 25/39 (64%) Frame = +2 Query: 116 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 232 ++ +GL +MG+ + N+ G+ V +NRT+SK +E + Sbjct: 2 EVGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELV 40 >UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC107852 protein - Strongylocentrotus purpuratus Length = 432 Score = 33.9 bits (74), Expect = 4.6 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = +2 Query: 92 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKV 220 K + E I IGL +MG + +N+ G+ V +NRT KV Sbjct: 355 KDIKPTEKKIGFIGLGLMGTGMAMNLIKAGHKVTVWNRTSEKV 397 >UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4; Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase - Leptospira interrogans Length = 296 Score = 33.9 bits (74), Expect = 4.6 Identities = 12/47 (25%), Positives = 29/47 (61%) Frame = +2 Query: 107 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 247 N+ I++IG +MG+ + +N+ G+ + + R +SK+++ K+ + Sbjct: 3 NKYTISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQ 49 >UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate dehydrogenase, NAD-binding - Exiguobacterium sibiricum 255-15 Length = 293 Score = 33.9 bits (74), Expect = 4.6 Identities = 15/33 (45%), Positives = 20/33 (60%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK 217 I IGL VMGQ ++ N+ G+ V +NRT K Sbjct: 5 IGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEK 37 >UniRef50_A6FXV9 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 388 Score = 33.5 bits (73), Expect = 6.0 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Frame = -2 Query: 679 ITIFNSMCTILTKWPAPSSPTQSQHGSSLALAHMA---WKISFICGHAAGCPPGIKDGPY 509 + I + +L +W A +S T +H S ++ H+A W + G A PPG+ PY Sbjct: 18 VCILDPEAALLGRWRACTSVTGMKHLRSPSVHHLAIDPWSLKRFAGKARSRPPGLFAPPY 77 >UniRef50_Q5K969 Cluster: Ubiquinone metabolism-related protein, putative; n=2; Filobasidiella neoformans|Rep: Ubiquinone metabolism-related protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 300 Score = 33.5 bits (73), Expect = 6.0 Identities = 20/38 (52%), Positives = 24/38 (63%), Gaps = 3/38 (7%) Frame = -1 Query: 632 SIFTDPVTARFI---ISFSAYGLENFFYMRPCSRMPTR 528 S+F DP +A F+ ISFSAY F MRPC R+ TR Sbjct: 10 SLF-DPTSADFLVPLISFSAYFSVKSFTMRPCPRLLTR 46 >UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7; Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase - Enterococcus faecalis (Streptococcus faecalis) Length = 296 Score = 33.1 bits (72), Expect = 8.0 Identities = 16/42 (38%), Positives = 23/42 (54%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 244 I IG VMG+++I NM V +NRT SK ++ + A Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGA 45 >UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetella|Rep: Putative oxidoreductase - Bordetella pertussis Length = 305 Score = 33.1 bits (72), Expect = 8.0 Identities = 16/43 (37%), Positives = 25/43 (58%) Frame = +1 Query: 364 LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSG 492 LI LL G I+D G+S DT++ ++L+ G+ + VSG Sbjct: 90 LIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSG 132 >UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; Pedobacter sp. BAL39|Rep: Putative uncharacterized protein - Pedobacter sp. BAL39 Length = 292 Score = 33.1 bits (72), Expect = 8.0 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = +2 Query: 128 IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK*LGLP 271 IGL MG + + +KGY + +NRT+SK E + A+G K G P Sbjct: 18 IGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLV---AQGAKVAGTP 62 >UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-binding precursor; n=1; Acidiphilium cryptum JF-5|Rep: 6-phosphogluconate dehydrogenase, NAD-binding precursor - Acidiphilium cryptum (strain JF-5) Length = 292 Score = 33.1 bits (72), Expect = 8.0 Identities = 15/45 (33%), Positives = 25/45 (55%) Frame = +2 Query: 119 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 253 I +IGL MG + + ++G+ VC +NRT ++ E AK + Sbjct: 5 IGVIGLGRMGAAMAARLIERGHQVCGWNRTAARAEAIQGLAAKAS 49 >UniRef50_Q7PZR1 Cluster: ENSANGP00000015639; n=2; Culicidae|Rep: ENSANGP00000015639 - Anopheles gambiae str. PEST Length = 230 Score = 33.1 bits (72), Expect = 8.0 Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Frame = +3 Query: 600 EPCCDWVGEDGAGHFV-KMVHMELNMVICNL 689 +P CDWV EDG GH KM ++ C+L Sbjct: 106 DPVCDWVSEDGVGHLACKMRLIDSGNYSCHL 136 >UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin - Caenorhabditis elegans Length = 6048 Score = 33.1 bits (72), Expect = 8.0 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Frame = +1 Query: 322 LVKAGFAVDEFVKKLIPLLSKGDII-IDGGNSQYLDTQKWCKELSGT 459 ++K G +DE ++KL+ ++ K D+ I N Q DT KW EL + Sbjct: 423 ILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNS 469 >UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229; n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase slr0229 - Synechocystis sp. (strain PCC 6803) Length = 290 Score = 33.1 bits (72), Expect = 8.0 Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 2/49 (4%) Frame = +2 Query: 107 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK--VEEFLKNEAK 247 N + IA+ GL VMG + N+ GY +NRT+ + V+E K K Sbjct: 2 NVSKIAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVK 50 >UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydiaceae|Rep: UvrABC system protein C - Chlamydophila caviae Length = 605 Score = 33.1 bits (72), Expect = 8.0 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +1 Query: 391 IIIDGGNSQYLDTQKWCKELSGTGILYVGM 480 I+IDGG +QY +K KEL+ TGI V + Sbjct: 453 IVIDGGRAQYSQAKKTLKELNLTGIQVVSL 482 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 783,381,497 Number of Sequences: 1657284 Number of extensions: 16325494 Number of successful extensions: 40624 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 38976 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 40530 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 65438977305 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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