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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbS20898
         (609 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2MHH4 Cluster: Protein Ku70; n=19; Fungi/Metazoa group...    52   1e-05
UniRef50_A7RH48 Cluster: Predicted protein; n=1; Nematostella ve...    51   2e-05
UniRef50_UPI0000E45E6A Cluster: PREDICTED: similar to Ku70; n=4;...    50   4e-05
UniRef50_Q7QCL6 Cluster: ENSANGP00000010850; n=1; Anopheles gamb...    47   3e-04
UniRef50_Q4WUA2 Cluster: DSB repair complex subunit Ku70, putati...    47   3e-04
UniRef50_Q26228 Cluster: ATP-dependent DNA helicase 2 subunit 1;...    46   0.001
UniRef50_Q9FQ08 Cluster: Ku70-like protein; n=8; Magnoliophyta|R...    44   0.003
UniRef50_Q2H0I3 Cluster: Protein Ku70; n=2; Sordariomycetes|Rep:...    43   0.005
UniRef50_A2YIV5 Cluster: Putative uncharacterized protein; n=1; ...    41   0.020
UniRef50_A3BH97 Cluster: Putative uncharacterized protein; n=3; ...    40   0.035
UniRef50_Q2NGP9 Cluster: Member of asn/thr-rich large protein fa...    40   0.035
UniRef50_P12956 Cluster: ATP-dependent DNA helicase 2 subunit 1;...    39   0.081
UniRef50_Q4P415 Cluster: Putative uncharacterized protein; n=1; ...    37   0.43 
UniRef50_A0DDG8 Cluster: Chromosome undetermined scaffold_46, wh...    35   1.7  
UniRef50_Q8I612 Cluster: Putative uncharacterized protein; n=1; ...    33   4.0  
UniRef50_Q556G9 Cluster: Putative uncharacterized protein; n=2; ...    33   4.0  
UniRef50_A0RNP3 Cluster: Putative uncharacterized protein; n=1; ...    33   5.3  
UniRef50_A0RPJ0 Cluster: Cytolethal distending toxin A/C family;...    33   7.0  
UniRef50_A6VY73 Cluster: Transcriptional regulator, GntR family;...    32   9.3  
UniRef50_Q9GUN4 Cluster: Putative uncharacterized protein; n=2; ...    32   9.3  

>UniRef50_Q2MHH4 Cluster: Protein Ku70; n=19; Fungi/Metazoa
           group|Rep: Protein Ku70 - Aspergillus oryzae
          Length = 655

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/97 (31%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
 Frame = +1

Query: 298 KSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWF-LKNCSFLF 474
           K E+    ++G + +AFT  E K++ N FG   ++++GFKP + L    W  +K+ SF++
Sbjct: 338 KWEIKKAYKFGGDQVAFTPEEMKSLRN-FGDPVIRIIGFKPLSAL--PFWANIKHPSFIY 394

Query: 475 PNEKSIEGSTTVSRQCTKHVLKQKL*LFV*FVLE*NS 585
           P+E+   GST V     + +L+ K    V F+   N+
Sbjct: 395 PSEEDFVGSTRVFSALHQTLLRDKKAALVWFIARKNA 431


>UniRef50_A7RH48 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 607

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 28/73 (38%), Positives = 43/73 (58%)
 Frame = +1

Query: 292 LLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFL 471
           L+ +++   Q++G E I F   E  ++   FG   L L+GFKP   L K  + +K   F+
Sbjct: 308 LMPTDIKFYQKFGGEKIIFEKEEVASMKK-FGDPGLLLMGFKPRVTL-KRFYHVKPAHFI 365

Query: 472 FPNEKSIEGSTTV 510
           +P+EKSI GSTT+
Sbjct: 366 YPDEKSITGSTTL 378


>UniRef50_UPI0000E45E6A Cluster: PREDICTED: similar to Ku70; n=4;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Ku70 - Strongylocentrotus purpuratus
          Length = 281

 Score = 50.0 bits (114), Expect = 4e-05
 Identities = 27/73 (36%), Positives = 42/73 (57%)
 Frame = +1

Query: 292 LLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFL 471
           L+ S++   Q YG + I F  +E   +   + P  L L+GFKP + L K+ + +K   FL
Sbjct: 10  LMPSDIKKYQTYGGKNIIFEKDEVDEVKKFYDPG-LTLMGFKPRSAL-KKYFHVKPAQFL 67

Query: 472 FPNEKSIEGSTTV 510
           FP+E S+ GS T+
Sbjct: 68  FPDETSVSGSNTL 80


>UniRef50_Q7QCL6 Cluster: ENSANGP00000010850; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000010850 - Anopheles gambiae
           str. PEST
          Length = 498

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 31/93 (33%), Positives = 46/93 (49%)
 Frame = +1

Query: 265 DRVEEQEMPLLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEK 444
           +R EE    LL  E       G E ++F   E   +     P  ++LLGFKP + + K  
Sbjct: 262 EREEEDTKVLLPGEQRKSIAIGGEKVSFKPEEVAQMKQLLPPG-IRLLGFKPASVI-KMT 319

Query: 445 WFLKNCSFLFPNEKSIEGSTTVSRQCTKHVLKQ 543
             L++  FL+PNE  I GSTT+ R   +  L++
Sbjct: 320 NHLRSSLFLYPNESYINGSTTLYRALYEKCLEK 352


>UniRef50_Q4WUA2 Cluster: DSB repair complex subunit Ku70, putative;
           n=3; Trichocomaceae|Rep: DSB repair complex subunit
           Ku70, putative - Aspergillus fumigatus (Sartorya
           fumigata)
          Length = 691

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
 Frame = +1

Query: 298 KSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWF-LKNCSFLF 474
           KSE+    ++GN+ ++FT  E K + + FG   ++++GFKP + L    W  +K+  F++
Sbjct: 337 KSEIRKAYKFGNDQVSFTPEEQKALRH-FGDPVIRIIGFKPLSAL--PFWANVKHPFFIY 393

Query: 475 PNEKSIEGSTTVSRQCTKHVLKQKL*LFV*FV 570
           P+E+   GST V     + +LK      V F+
Sbjct: 394 PSEEDYVGSTRVFSALHQKLLKDHKMALVWFI 425


>UniRef50_Q26228 Cluster: ATP-dependent DNA helicase 2 subunit 1;
           n=1; Rhipicephalus appendiculatus|Rep: ATP-dependent DNA
           helicase 2 subunit 1 - Rhipicephalus appendiculatus
           (Brown ear tick)
          Length = 600

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/86 (31%), Positives = 46/86 (53%)
 Frame = +1

Query: 292 LLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFL 471
           L+  ++   QEYG     F   E K I +   P  L+LLGFKP ++L K+   ++   F+
Sbjct: 297 LMPGDISKTQEYGGRKAYFDICEVKQIKS-MAPPGLQLLGFKPLSYLEKQP-HVRPSHFV 354

Query: 472 FPNEKSIEGSTTVSRQCTKHVLKQKL 549
           +P+E S+ GST +     +  L+ ++
Sbjct: 355 YPDEGSVRGSTRLFAALLQSCLRHRV 380


>UniRef50_Q9FQ08 Cluster: Ku70-like protein; n=8; Magnoliophyta|Rep:
           Ku70-like protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 621

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/71 (35%), Positives = 39/71 (54%)
 Frame = +1

Query: 292 LLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFL 471
           +++  +   Q Y N+ I FT  E   +        L+LLGFKP + L K+   LK  +FL
Sbjct: 321 IMQDPIQRIQPYKNQNIMFTVEELSQVKR-ISTGHLRLLGFKPLSCL-KDYHNLKPSTFL 378

Query: 472 FPNEKSIEGST 504
           +P++K + GST
Sbjct: 379 YPSDKEVIGST 389


>UniRef50_Q2H0I3 Cluster: Protein Ku70; n=2; Sordariomycetes|Rep:
           Protein Ku70 - Chaetomium globosum (Soil fungus)
          Length = 622

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
 Frame = +1

Query: 268 RVEEQEMPLLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKW 447
           +V+     + KSE+    ++G E I F   E  ++ N  G   L+++GFKP + L    W
Sbjct: 319 KVDSATRTVDKSEVKKAYKFGGEYIHFKPEEAASLKN-LGGKVLRVIGFKPRSLL--PTW 375

Query: 448 F-LKNCSFLFPNEKSIEGST 504
             +K   F+FP+E+   GST
Sbjct: 376 ASVKKSIFIFPSEEHFVGST 395


>UniRef50_A2YIV5 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 408

 Score = 41.1 bits (92), Expect = 0.020
 Identities = 24/73 (32%), Positives = 40/73 (54%)
 Frame = +1

Query: 292 LLKSELLHCQEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFL 471
           LL+      Q Y ++I+ F+  E   +        L+LLGFKP  +L K+   L+  +F+
Sbjct: 293 LLQDPQKRFQVYNDKIVKFSTRELSDVKR-VSSHHLRLLGFKPLDYL-KDYHNLRPSTFI 350

Query: 472 FPNEKSIEGSTTV 510
           +P+++ I GST V
Sbjct: 351 YPSDEQIFGSTRV 363


>UniRef50_A3BH97 Cluster: Putative uncharacterized protein; n=3;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 594

 Score = 40.3 bits (90), Expect = 0.035
 Identities = 22/64 (34%), Positives = 37/64 (57%)
 Frame = +1

Query: 319 QEYGNEIIAFTDNEFKTINNPFGPAKLKLLGFKPETFLCKEKWFLKNCSFLFPNEKSIEG 498
           Q Y ++I+ F+  E   +        L+LLGFKP  +L K+   L+  +F++P+++ I G
Sbjct: 488 QVYNDKIVKFSTRELSDVKR-VSSHHLRLLGFKPLDYL-KDYHNLRPSTFIYPSDEQIFG 545

Query: 499 STTV 510
           ST V
Sbjct: 546 STRV 549


>UniRef50_Q2NGP9 Cluster: Member of asn/thr-rich large protein family;
            n=1; Methanosphaera stadtmanae DSM 3091|Rep: Member of
            asn/thr-rich large protein family - Methanosphaera
            stadtmanae (strain DSM 3091)
          Length = 2459

 Score = 40.3 bits (90), Expect = 0.035
 Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
 Frame = +2

Query: 53   LILNECDRHLATAQLIFEIGNNVSIGISIYKLLKSNIEPKKVYLS-NETNAVVTSDTKTT 229
            +IL+ CD  L T++  F++  N SIGISIY    + IE     LS N T A+     K+ 
Sbjct: 1582 VILSACD-DLVTSRNNFKLNGNTSIGISIYGTSNNTIEFNDFKLSGNSTKAIEV--IKSN 1638

Query: 230  KVLVKPDTVWIL 265
            +++++ +T+ IL
Sbjct: 1639 EIILRSNTITIL 1650


>UniRef50_P12956 Cluster: ATP-dependent DNA helicase 2 subunit 1;
           n=45; Euteleostomi|Rep: ATP-dependent DNA helicase 2
           subunit 1 - Homo sapiens (Human)
          Length = 609

 Score = 39.1 bits (87), Expect = 0.081
 Identities = 18/65 (27%), Positives = 37/65 (56%)
 Frame = +2

Query: 32  KIEDVTKLILNECDRHLATAQLIFEIGNNVSIGISIYKLLKSNIEPKKVYLSNETNAVVT 211
           K+ED+ + +  +  R  A ++L  ++  ++ I + IY L++  ++P  + L  ETN  V 
Sbjct: 238 KLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVK 297

Query: 212 SDTKT 226
           + T+T
Sbjct: 298 TKTRT 302


>UniRef50_Q4P415 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 713

 Score = 36.7 bits (81), Expect = 0.43
 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
 Frame = +1

Query: 289 PLLKSELLHCQEYGNEI-----IAFTDNEFKTINNPFGPA-KLKLLGFKPETFLCKEKWF 450
           PL K +++   ++G        + FT  E ++I   FG    LKL+GF+    L + +W 
Sbjct: 400 PLSKDQVIPAFQFGPSSSLRGQVTFTPGELRSIKT-FGMLPSLKLIGFRNRDDLLRFEWN 458

Query: 451 LKNCSFLFPNEKSIEGS 501
           +K+  F++P++   +GS
Sbjct: 459 VKHSYFIYPSDSEWKGS 475


>UniRef50_A0DDG8 Cluster: Chromosome undetermined scaffold_46, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_46,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 2450

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 19/58 (32%), Positives = 26/58 (44%)
 Frame = +2

Query: 134 SIYKLLKSNIEPKKVYLSNETNAVVTSDTKTTKVLVKPDTVWILIGLKNKKCLYLSLS 307
           S +K ++   EP K  L N  N   T+     K+  K  T W++    N KC Y S S
Sbjct: 820 SNFKCIEVKDEPYKNVLLNTLNCTQTNLNLCGKITTKGQTCWVVDNNSNLKCSYYSAS 877


>UniRef50_Q8I612 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium falciparum 3D7|Rep: Putative uncharacterized
           protein - Plasmodium falciparum (isolate 3D7)
          Length = 992

 Score = 33.5 bits (73), Expect = 4.0
 Identities = 19/70 (27%), Positives = 33/70 (47%)
 Frame = +2

Query: 116 NVSIGISIYKLLKSNIEPKKVYLSNETNAVVTSDTKTTKVLVKPDTVWILIGLKNKKCLY 295
           N+ I +    L   N+    +Y+  ETN ++  DT+  ++       + ++  K K+CL 
Sbjct: 595 NIDIHLVTRNLKVENVIDTNIYVYTETNIIIFGDTRNIQL-----APYNILNTKQKECLD 649

Query: 296 LSLSCFTVKN 325
            S   FT KN
Sbjct: 650 KSKIIFTEKN 659


>UniRef50_Q556G9 Cluster: Putative uncharacterized protein; n=2;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 406

 Score = 33.5 bits (73), Expect = 4.0
 Identities = 15/52 (28%), Positives = 30/52 (57%)
 Frame = +2

Query: 140 YKLLKSNIEPKKVYLSNETNAVVTSDTKTTKVLVKPDTVWILIGLKNKKCLY 295
           YK+L+S I+  K  +  + N +V+ +TKTTK +   +  + ++G +  +  Y
Sbjct: 26  YKVLESTIQDDKKKIEKKYNELVSEETKTTKEIEAIENAFKILGTEKYRNAY 77


>UniRef50_A0RNP3 Cluster: Putative uncharacterized protein; n=1;
           Campylobacter fetus subsp. fetus 82-40|Rep: Putative
           uncharacterized protein - Campylobacter fetus subsp.
           fetus (strain 82-40)
          Length = 245

 Score = 33.1 bits (72), Expect = 5.3
 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
 Frame = +1

Query: 412 FKPE-TFLCKEKWFLKNCSFLFPNEKSIEGSTTVSRQCTKHVLKQ 543
           FKPE  ++C E W +K+   LFPNEK  EGS  V  +     LK+
Sbjct: 96  FKPEGAYIC-ESWIVKSGDPLFPNEK--EGSWAVGIKLESDELKE 137


>UniRef50_A0RPJ0 Cluster: Cytolethal distending toxin A/C family;
           n=1; Campylobacter fetus subsp. fetus 82-40|Rep:
           Cytolethal distending toxin A/C family - Campylobacter
           fetus subsp. fetus (strain 82-40)
          Length = 183

 Score = 32.7 bits (71), Expect = 7.0
 Identities = 18/79 (22%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
 Frame = +2

Query: 2   NKNSLPKSVWKIEDVTKLILNECDRHLATAQLIFEIGNNVSIGISIY-KLLKSNIEPKKV 178
           N +SL K+ W + ++T   +   D    T Q +  + +NV +G+S+  KL   + E   V
Sbjct: 49  NPSSLIKTNWNLREITLPYIISKDYPFGTVQFVSPVNDNVCLGLSLAGKLTTMSCESTAV 108

Query: 179 YLSNETNAVVTSDTKTTKV 235
                  +++ ++T   ++
Sbjct: 109 GNYGSVFSILPTNTSAVQI 127


>UniRef50_A6VY73 Cluster: Transcriptional regulator, GntR family;
           n=1; Marinomonas sp. MWYL1|Rep: Transcriptional
           regulator, GntR family - Marinomonas sp. MWYL1
          Length = 219

 Score = 32.3 bits (70), Expect = 9.3
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
 Frame = +2

Query: 44  VTKLILNECDRHLATAQLIFEIGNNVSIGISIYKLLKSNIEPKKVYLSN---ETNAVVTS 214
           V++ I+ EC RHL + +L+  I N+  +  SI     SN E K++Y      E +AV   
Sbjct: 44  VSRTIVRECIRHLESERLVVGIPNSGFVVASI-----SNAEVKEIYEIRTLLECSAVKAC 98

Query: 215 DTKTTKVLVK 244
             K T  ++K
Sbjct: 99  SLKATPTVIK 108


>UniRef50_Q9GUN4 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 460

 Score = 32.3 bits (70), Expect = 9.3
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
 Frame = +2

Query: 5   KNSLPKSVWKIEDVTKL----ILNECDRHLATAQLIFEIGNNVSIGISIYKLLKSNIEPK 172
           KN +   V K+E+  +L    I+  C   +    LI E    ++  +++     SN+E +
Sbjct: 35  KNFIISYVRKLEENKELYSAGIVGTCMPDIFRKPLILETPTAITHELTLQWTTVSNVEEQ 94

Query: 173 KVYLSNETNAVVTSDTKTTKVL 238
           KV +++E + +   DTKT K L
Sbjct: 95  KVMVTDENSTMSEVDTKTLKDL 116


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 526,599,070
Number of Sequences: 1657284
Number of extensions: 9648464
Number of successful extensions: 25477
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 24679
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25468
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43562448615
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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