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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbS20773
         (657 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U80226-1|AAB38510.1|  500|Homo sapiens gamma-aminobutyric acid t...    97   5e-20
S75578-1|AAD14176.1|  450|Homo sapiens 4-aminobutyrate aminotran...    97   5e-20
BC015628-1|AAH15628.1|  500|Homo sapiens 4-aminobutyrate aminotr...    97   5e-20
BC031413-1|AAH31413.1|  500|Homo sapiens 4-aminobutyrate aminotr...    95   1e-19
L32961-1|AAA74449.1|  500|Homo sapiens 4-aminobutyrate aminotran...    92   1e-18
AK223128-1|BAD96848.1|  502|Homo sapiens alanine-glyoxylate amin...    36   0.13 
AB193309-1|BAD66662.1|  514|Homo sapiens beta-alanine-pyruvate a...    36   0.13 
AK223375-1|BAD97095.1|  514|Homo sapiens alanine-glyoxylate amin...    34   0.51 
AJ292204-1|CAC24841.1|  514|Homo sapiens alanine-glyoxylate amin...    34   0.51 
L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula oc...    32   2.1  
DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein ...    32   2.1  
BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein ...    32   2.1  

>U80226-1|AAB38510.1|  500|Homo sapiens gamma-aminobutyric acid
           transaminase protein.
          Length = 500

 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 40/80 (50%), Positives = 57/80 (71%)
 Frame = +1

Query: 259 DKPNIQTAIPGPKSQQLLKELNTLQQAGAVQLFADYDKSIGNYFFDADGNAFLDAFTQIS 438
           D P ++T +PGP+SQ+L+K+LN +Q A AV  F +Y++S GNY  D DGN  LD ++QIS
Sbjct: 42  DGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQIS 101

Query: 439 SLPVGYNHPELLSAFEDQHN 498
           S+P+GY+HP LL   +   N
Sbjct: 102 SVPIGYSHPALLKLIQQPQN 121



 Score = 41.1 bits (92), Expect = 0.003
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +3

Query: 510 INRPALGVFPSADWPEKLKNVLLSVGPVGLDNIAPMMCGXCSIENAYKT 656
           +NRPALG+ P  ++ EKL+  LLSV P G  + +P       ++   KT
Sbjct: 126 VNRPALGILPPENFVEKLRQSLLSVAPKGCPSSSPWPACPAPMKTTLKT 174


>S75578-1|AAD14176.1|  450|Homo sapiens 4-aminobutyrate
           aminotransferase protein.
          Length = 450

 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 40/80 (50%), Positives = 57/80 (71%)
 Frame = +1

Query: 259 DKPNIQTAIPGPKSQQLLKELNTLQQAGAVQLFADYDKSIGNYFFDADGNAFLDAFTQIS 438
           D P ++T +PGP+SQ+L+K+LN +Q A AV  F +Y++S GNY  D DGN  LD ++QIS
Sbjct: 7   DGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQIS 66

Query: 439 SLPVGYNHPELLSAFEDQHN 498
           S+P+GY+HP LL   +   N
Sbjct: 67  SVPIGYSHPALLKLIQQPQN 86



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/49 (53%), Positives = 33/49 (67%)
 Frame = +3

Query: 510 INRPALGVFPSADWPEKLKNVLLSVGPVGLDNIAPMMCGXCSIENAYKT 656
           +NRPALG+ P  ++ EKL+  LLSV P G+  +  M CG CS ENA KT
Sbjct: 91  VNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKT 139


>BC015628-1|AAH15628.1|  500|Homo sapiens 4-aminobutyrate
           aminotransferase protein.
          Length = 500

 Score = 97.1 bits (231), Expect = 5e-20
 Identities = 40/80 (50%), Positives = 57/80 (71%)
 Frame = +1

Query: 259 DKPNIQTAIPGPKSQQLLKELNTLQQAGAVQLFADYDKSIGNYFFDADGNAFLDAFTQIS 438
           D P ++T +PGP+SQ+L+K+LN +Q A AV  F +Y++S GNY  D DGN  LD ++QIS
Sbjct: 42  DGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQIS 101

Query: 439 SLPVGYNHPELLSAFEDQHN 498
           S+P+GY+HP LL   +   N
Sbjct: 102 SVPIGYSHPALLKLIQQPQN 121



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/49 (53%), Positives = 33/49 (67%)
 Frame = +3

Query: 510 INRPALGVFPSADWPEKLKNVLLSVGPVGLDNIAPMMCGXCSIENAYKT 656
           +NRPALG+ P  ++ EKL+  LLSV P G+  +  M CG CS ENA KT
Sbjct: 126 VNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKT 174


>BC031413-1|AAH31413.1|  500|Homo sapiens 4-aminobutyrate
           aminotransferase protein.
          Length = 500

 Score = 95.5 bits (227), Expect = 1e-19
 Identities = 39/80 (48%), Positives = 57/80 (71%)
 Frame = +1

Query: 259 DKPNIQTAIPGPKSQQLLKELNTLQQAGAVQLFADYDKSIGNYFFDADGNAFLDAFTQIS 438
           D P ++T +PGP+S++L+K+LN +Q A AV  F +Y++S GNY  D DGN  LD ++QIS
Sbjct: 42  DGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQIS 101

Query: 439 SLPVGYNHPELLSAFEDQHN 498
           S+P+GY+HP LL   +   N
Sbjct: 102 SVPIGYSHPALLKLIQQPQN 121



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 26/49 (53%), Positives = 33/49 (67%)
 Frame = +3

Query: 510 INRPALGVFPSADWPEKLKNVLLSVGPVGLDNIAPMMCGXCSIENAYKT 656
           +NRPALG+ P  ++ EKL+  LLSV P G+  +  M CG CS ENA KT
Sbjct: 126 VNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKT 174


>L32961-1|AAA74449.1|  500|Homo sapiens 4-aminobutyrate
           aminotransferase protein.
          Length = 500

 Score = 92.3 bits (219), Expect = 1e-18
 Identities = 38/80 (47%), Positives = 56/80 (70%)
 Frame = +1

Query: 259 DKPNIQTAIPGPKSQQLLKELNTLQQAGAVQLFADYDKSIGNYFFDADGNAFLDAFTQIS 438
           D P ++T +PGP+SQ+L+K+LN +Q A AV  F +Y++S GNY  D DGN  LD ++QIS
Sbjct: 42  DGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQIS 101

Query: 439 SLPVGYNHPELLSAFEDQHN 498
           S+P+GY+ P L+   +   N
Sbjct: 102 SVPIGYSDPALVKLIQQPQN 121



 Score = 56.4 bits (130), Expect = 8e-08
 Identities = 25/49 (51%), Positives = 32/49 (65%)
 Frame = +3

Query: 510 INRPALGVFPSADWPEKLKNVLLSVGPVGLDNIAPMMCGXCSIENAYKT 656
           +NRPAL + P  ++ EKL+  LLSV P G+  +  M CG CS ENA KT
Sbjct: 126 VNRPALEILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKT 174


>AK223128-1|BAD96848.1|  502|Homo sapiens alanine-glyoxylate
           aminotransferase 2 precursor variant protein.
          Length = 502

 Score = 35.9 bits (79), Expect = 0.13
 Identities = 17/48 (35%), Positives = 30/48 (62%)
 Frame = +1

Query: 385 YFFDADGNAFLDAFTQISSLPVGYNHPELLSAFEDQHNLKS*LIGQLW 528
           + FDA+GN +LD F+ I ++ VG+ HP++ +  + Q       +G+LW
Sbjct: 83  WLFDAEGNRYLDFFSGIVTVSVGHCHPKVNAVAQKQ-------LGRLW 123


>AB193309-1|BAD66662.1|  514|Homo sapiens beta-alanine-pyruvate
           aminotransferase protein.
          Length = 514

 Score = 35.9 bits (79), Expect = 0.13
 Identities = 17/48 (35%), Positives = 30/48 (62%)
 Frame = +1

Query: 385 YFFDADGNAFLDAFTQISSLPVGYNHPELLSAFEDQHNLKS*LIGQLW 528
           + FDA+GN +LD F+ I ++ VG+ HP++ +  + Q       +G+LW
Sbjct: 95  WLFDAEGNRYLDFFSGIVTVSVGHCHPKVNAVAQKQ-------LGRLW 135


>AK223375-1|BAD97095.1|  514|Homo sapiens alanine-glyoxylate
           aminotransferase 2 precursor variant protein.
          Length = 514

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 16/48 (33%), Positives = 30/48 (62%)
 Frame = +1

Query: 385 YFFDADGNAFLDAFTQISSLPVGYNHPELLSAFEDQHNLKS*LIGQLW 528
           + FDA+G+ +LD F+ I ++ VG+ HP++ +  + Q       +G+LW
Sbjct: 95  WLFDAEGSRYLDFFSGIVTVSVGHCHPKVNAVAQKQ-------LGRLW 135


>AJ292204-1|CAC24841.1|  514|Homo sapiens alanine-glyoxylate
           aminotransferase 2 protein.
          Length = 514

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 16/48 (33%), Positives = 30/48 (62%)
 Frame = +1

Query: 385 YFFDADGNAFLDAFTQISSLPVGYNHPELLSAFEDQHNLKS*LIGQLW 528
           + FDA+G+ +LD F+ I ++ VG+ HP++ +  + Q       +G+LW
Sbjct: 95  WLFDAEGSRYLDFFSGIVTVSVGHCHPKVNAVAQKQ-------LGRLW 135


>L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula
            occludens) protein ZO-1 protein.
          Length = 1736

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
 Frame = -3

Query: 640  SIEQXP--HIIGAMLSNPTGPTDNNTFFNFSGQSAEGKTPRA 521
            S E  P  HI  + LS P  P  +    NFS  S++GK P A
Sbjct: 1354 SFENKPPAHIAASHLSEPAKPAHSQNQSNFSSYSSKGKPPEA 1395


>DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein 1
            (zona occludens 1) protein.
          Length = 1748

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
 Frame = -3

Query: 640  SIEQXP--HIIGAMLSNPTGPTDNNTFFNFSGQSAEGKTPRA 521
            S E  P  HI  + LS P  P  +    NFS  S++GK P A
Sbjct: 1366 SFENKPPAHIAASHLSEPAKPAHSQNQSNFSSYSSKGKPPEA 1407


>BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein 1
            (zona occludens 1) protein.
          Length = 1748

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
 Frame = -3

Query: 640  SIEQXP--HIIGAMLSNPTGPTDNNTFFNFSGQSAEGKTPRA 521
            S E  P  HI  + LS P  P  +    NFS  S++GK P A
Sbjct: 1366 SFENKPPAHIAASHLSEPAKPAHSQNQSNFSSYSSKGKPPEA 1407


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,942,855
Number of Sequences: 237096
Number of extensions: 1693429
Number of successful extensions: 3038
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 2770
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3038
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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