Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbS20075
(756 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 44 4e-04
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 44 4e-04
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 44 4e-04
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 44 4e-04
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 44 4e-04
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 44 4e-04
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 44 4e-04
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 44 4e-04
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 44 4e-04
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 44 4e-04
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 44 4e-04
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 44 6e-04
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 40 0.010
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 36 0.21
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 36 0.21
BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding doma... 31 5.9
AY186997-1|AAP12462.1| 1024|Homo sapiens WAMTP1-MAML2 fusion pro... 31 5.9
AY040324-1|AAK93833.1| 1024|Homo sapiens MECT1/MAML2 fusion prot... 31 5.9
AY040322-1|AAK93831.1| 1153|Homo sapiens nuclear transcription f... 31 5.9
AJ972402-1|CAI99884.1| 637|Homo sapiens MLL-MAML2 protein. 31 5.9
AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.9
AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.9
AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein. 31 5.9
AB058722-1|BAB47448.1| 1173|Homo sapiens KIAA1819 protein protein. 31 5.9
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 30 7.8
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 30 7.8
AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide exch... 30 7.8
AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited g... 30 7.8
AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited g... 30 7.8
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 485 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 526
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 486 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 527
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 486 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 527
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 199 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 240
Score = 33.5 bits (73), Expect = 0.84
Identities = 12/28 (42%), Positives = 17/28 (60%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEK 313
G+ + +K ++CGAV HC TVW K
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNK 55
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 524
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/44 (45%), Positives = 22/44 (50%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWS 750
P HK LLG +C WGPSYWC N A HC VW+
Sbjct: 489 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVWN 530
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 31 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 88
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 89 ILVYLEKTCDWLPKPNMSASCKE 111
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 22 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 58
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 44.0 bits (99), Expect = 6e-04
Identities = 20/43 (46%), Positives = 21/43 (48%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVW 747
P HK LLG +C WGPSYWC N A HC VW
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNT-ETAAQCNAVEHCKRHVW 523
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/83 (27%), Positives = 37/83 (44%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 409
G+ + +K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 410 LAASIESACHDIQYPAIAKICKD 478
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
+LG CT G + WC N A + HC+ VW+K
Sbjct: 19 VLGLKECTRGSAVWCQNV-KTASDCGAVKHCLQTVWNK 55
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +1
Query: 619 PVKHKDQLLGKSRCTWGPSYWCSN 690
P HK LLG +C WGPSYWC N
Sbjct: 180 PSAHKP-LLGTEKCIWGPSYWCQN 202
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 35.5 bits (78), Expect = 0.21
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEK 313
G+T ++L+ A CGAVG+C VW K
Sbjct: 29 GSTVWCQDLQTAARCGAVGYCQGAVWNK 56
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
LLG +C GPS+WC + A+ HC VW +
Sbjct: 476 LLGTDQCALGPSFWCRSQ-EAAKLCNAVQHCQKHVWKE 512
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 35.5 bits (78), Expect = 0.21
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +2
Query: 230 GTTSMVRELKRGAECGAVGHCTATVWEK 313
G+T ++L+ A CGAVG+C VW K
Sbjct: 51 GSTVWCQDLQTAARCGAVGYCQGAVWNK 78
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +1
Query: 640 LLGKSRCTWGPSYWCSNF*HWAENATLRLHCINRVWSK 753
LLG +C GPS+WC + A+ HC VW +
Sbjct: 498 LLGTDQCALGPSFWCRSQ-EAAKLCNAVQHCQKHVWKE 534
>BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding domain
protein 2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 305 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 469
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AY186997-1|AAP12462.1| 1024|Homo sapiens WAMTP1-MAML2 fusion protein
protein.
Length = 1024
Score = 30.7 bits (66), Expect = 5.9
Identities = 22/73 (30%), Positives = 31/73 (42%)
Frame = -3
Query: 292 TVSNRAAFSPPL*LSHHTCGPLAHSSVLVAQTTNLYNKGTLETVDKQQTCLSSLRM*FKF 113
+V N P L S + P S+V++ T N + E KQQ L+S + F
Sbjct: 797 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 856
Query: 112 NTPALILALQILK 74
TPA Q L+
Sbjct: 857 GTPAAYTPNQSLQ 869
>AY040324-1|AAK93833.1| 1024|Homo sapiens MECT1/MAML2 fusion protein
protein.
Length = 1024
Score = 30.7 bits (66), Expect = 5.9
Identities = 22/73 (30%), Positives = 31/73 (42%)
Frame = -3
Query: 292 TVSNRAAFSPPL*LSHHTCGPLAHSSVLVAQTTNLYNKGTLETVDKQQTCLSSLRM*FKF 113
+V N P L S + P S+V++ T N + E KQQ L+S + F
Sbjct: 797 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 856
Query: 112 NTPALILALQILK 74
TPA Q L+
Sbjct: 857 GTPAAYTPNQSLQ 869
>AY040322-1|AAK93831.1| 1153|Homo sapiens nuclear transcription
factor/notch receptor regulator protein.
Length = 1153
Score = 30.7 bits (66), Expect = 5.9
Identities = 22/73 (30%), Positives = 31/73 (42%)
Frame = -3
Query: 292 TVSNRAAFSPPL*LSHHTCGPLAHSSVLVAQTTNLYNKGTLETVDKQQTCLSSLRM*FKF 113
+V N P L S + P S+V++ T N + E KQQ L+S + F
Sbjct: 926 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 985
Query: 112 NTPALILALQILK 74
TPA Q L+
Sbjct: 986 GTPAAYTPNQSLQ 998
>AJ972402-1|CAI99884.1| 637|Homo sapiens MLL-MAML2 protein.
Length = 637
Score = 30.7 bits (66), Expect = 5.9
Identities = 22/73 (30%), Positives = 31/73 (42%)
Frame = -3
Query: 292 TVSNRAAFSPPL*LSHHTCGPLAHSSVLVAQTTNLYNKGTLETVDKQQTCLSSLRM*FKF 113
+V N P L S + P S+V++ T N + E KQQ L+S + F
Sbjct: 410 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 469
Query: 112 NTPALILALQILK 74
TPA Q L+
Sbjct: 470 GTPAAYTPNQSLQ 482
>AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding protein
2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 305 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 469
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding protein
MBD2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 305 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 469
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein.
Length = 200
Score = 30.7 bits (66), Expect = 5.9
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +2
Query: 305 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 469
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 72 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 129
>AB058722-1|BAB47448.1| 1173|Homo sapiens KIAA1819 protein protein.
Length = 1173
Score = 30.7 bits (66), Expect = 5.9
Identities = 22/73 (30%), Positives = 31/73 (42%)
Frame = -3
Query: 292 TVSNRAAFSPPL*LSHHTCGPLAHSSVLVAQTTNLYNKGTLETVDKQQTCLSSLRM*FKF 113
+V N P L S + P S+V++ T N + E KQQ L+S + F
Sbjct: 946 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 1005
Query: 112 NTPALILALQILK 74
TPA Q L+
Sbjct: 1006 GTPAAYTPNQSLQ 1018
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 30.3 bits (65), Expect = 7.8
Identities = 24/106 (22%), Positives = 40/106 (37%), Gaps = 1/106 (0%)
Frame = +2
Query: 248 RELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 427
+ L++ +C A+GHC VW D E V + K K+ I ++ + +E
Sbjct: 41 QSLEQALQCRALGHCLQEVWGHVGADDLCQECED-IVHILN--KMAKEAIFQDTMRKFLE 97
Query: 428 SACHDIQYPAIAKICKD-NTAHFENYIHTFSNRTHRPRQCAKSSAC 562
C+ + + C +F I F N+T C C
Sbjct: 98 QECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLC 143
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 30.3 bits (65), Expect = 7.8
Identities = 24/106 (22%), Positives = 40/106 (37%), Gaps = 1/106 (0%)
Frame = +2
Query: 248 RELKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 427
+ L++ +C A+GHC VW D E V + K K+ I ++ + +E
Sbjct: 41 QSLEQALQCRALGHCLQEVWGHVGADDLCQECED-IVHILN--KMAKEAIFQDTMRKFLE 97
Query: 428 SACHDIQYPAIAKICKD-NTAHFENYIHTFSNRTHRPRQCAKSSAC 562
C+ + + C +F I F N+T C C
Sbjct: 98 QECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLC 143
>AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 1849
Score = 30.3 bits (65), Expect = 7.8
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 320 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 418
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 protein.
Length = 1849
Score = 30.3 bits (65), Expect = 7.8
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 320 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 418
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 variant protein.
Length = 1278
Score = 30.3 bits (65), Expect = 7.8
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +2
Query: 320 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 418
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 319 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 350
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,193,895
Number of Sequences: 237096
Number of extensions: 2499900
Number of successful extensions: 6540
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 5949
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6521
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9127122082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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