Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbS20056
(596 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 111 1e-24
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 111 1e-24
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 111 1e-24
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 111 1e-24
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 105 2e-22
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 105 2e-22
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 105 2e-22
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 105 2e-22
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 105 2e-22
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 101 1e-21
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 101 1e-21
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 101 1e-21
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 100 3e-21
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 100 3e-21
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 100 3e-21
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 100 3e-21
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 100 3e-21
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 97 6e-20
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 71 4e-12
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 71 4e-12
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 70 7e-12
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 51 3e-06
AB077881-1|BAB83897.1| 1306|Homo sapiens caspr5 protein. 30 7.2
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 111 bits (268), Expect = 1e-24
Identities = 47/114 (41%), Positives = 75/114 (65%), Gaps = 3/114 (2%)
Frame = +2
Query: 203 TPGACLRPQQCG---CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNED 373
TPG+ ++ G C S YH D++++ L + YRFS+SW R+ PTG ++ +N
Sbjct: 938 TPGSNVKDNATGDIACDS--YHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSH 995
Query: 374 GLXYYSELLDTLHKNNIKPVVTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
G+ YY+ L++ L +NI P+VT++HWDLPQ+LQD+GGW NP ++D+ + +C
Sbjct: 996 GVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (257), Expect = 3e-23
Identities = 46/84 (54%), Positives = 58/84 (69%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH D+ + L +S YRFS+SW R+LP G + +NE GL YY L+DTL +I+P
Sbjct: 1429 YHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQ 1488
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIV 505
VTIYHWDLPQ+LQD+GGW N IV
Sbjct: 1489 VTIYHWDLPQTLQDVGGWENETIV 1512
Score = 96.3 bits (229), Expect = 7e-20
Identities = 39/94 (41%), Positives = 57/94 (60%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH DV L+ L Y+FS+SW R+ P G+ + + G+ YY++L+D L I+P+
Sbjct: 433 YHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPM 492
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
T++HWDLPQ+LQD GGW N +VD +C
Sbjct: 493 ATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 61.7 bits (143), Expect = 2e-09
Identities = 24/53 (45%), Positives = 36/53 (67%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
F F +GV+++++Q+EGAW+ GKG SIWD +TH V D++ D+A DS
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDS 955
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/53 (50%), Positives = 37/53 (69%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
FP+GF + A+A++Q+EGAW GKG SIWD ++H P RV + + DVA DS
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDS 1428
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 22/31 (70%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWD 188
FP+GF +G +T +F VEG W G+G SIWD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 43.6 bits (98), Expect = 5e-04
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F+DYA F+TFGDRV +W+TF+EP
Sbjct: 519 FLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 39.5 bits (88), Expect = 0.009
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEPL 588
F YA F TFGDRV W+TFNEP+
Sbjct: 1042 FDSYADFCFQTFGDRVKFWMTFNEPM 1067
Score = 39.1 bits (87), Expect = 0.012
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +2
Query: 299 LSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIYHWDLPQS 466
++ Y+ +SW ++LP G + +E + Y LL L ++P+V ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.083
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNE 582
F DYA F +FGD VG+W TF++
Sbjct: 151 FADYATFAFHSFGDLVGIWFTFSD 174
Score = 35.9 bits (79), Expect = 0.11
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 418 QHQTGSHYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
Q Q ++ L + G W + + F +YA +LF GD+V WIT NEP
Sbjct: 1486 QPQVTIYHWDLPQTLQDVGGW--ENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 111 bits (268), Expect = 1e-24
Identities = 47/114 (41%), Positives = 75/114 (65%), Gaps = 3/114 (2%)
Frame = +2
Query: 203 TPGACLRPQQCG---CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNED 373
TPG+ ++ G C S YH D++++ L + YRFS+SW R+ PTG ++ +N
Sbjct: 938 TPGSNVKDNATGDIACDS--YHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSH 995
Query: 374 GLXYYSELLDTLHKNNIKPVVTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
G+ YY+ L++ L +NI P+VT++HWDLPQ+LQD+GGW NP ++D+ + +C
Sbjct: 996 GVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (257), Expect = 3e-23
Identities = 46/84 (54%), Positives = 58/84 (69%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH D+ + L +S YRFS+SW R+LP G + +NE GL YY L+DTL +I+P
Sbjct: 1429 YHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQ 1488
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIV 505
VTIYHWDLPQ+LQD+GGW N IV
Sbjct: 1489 VTIYHWDLPQTLQDVGGWENETIV 1512
Score = 96.3 bits (229), Expect = 7e-20
Identities = 39/94 (41%), Positives = 57/94 (60%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH DV L+ L Y+FS+SW R+ P G+ + + G+ YY++L+D L I+P+
Sbjct: 433 YHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPM 492
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
T++HWDLPQ+LQD GGW N +VD +C
Sbjct: 493 ATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 61.7 bits (143), Expect = 2e-09
Identities = 24/53 (45%), Positives = 36/53 (67%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
F F +GV+++++Q+EGAW+ GKG SIWD +TH V D++ D+A DS
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDS 955
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/53 (50%), Positives = 37/53 (69%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
FP+GF + A+A++Q+EGAW GKG SIWD ++H P RV + + DVA DS
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDS 1428
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 22/31 (70%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWD 188
FP+GF +G +T +F VEG W G+G SIWD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 43.6 bits (98), Expect = 5e-04
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F+DYA F+TFGDRV +W+TF+EP
Sbjct: 519 FLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 39.5 bits (88), Expect = 0.009
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEPL 588
F YA F TFGDRV W+TFNEP+
Sbjct: 1042 FDSYADFCFQTFGDRVKFWMTFNEPM 1067
Score = 39.1 bits (87), Expect = 0.012
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +2
Query: 299 LSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIYHWDLPQS 466
++ Y+ +SW ++LP G + +E + Y LL L ++P+V ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.083
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNE 582
F DYA F +FGD VG+W TF++
Sbjct: 151 FADYATFAFHSFGDLVGIWFTFSD 174
Score = 35.9 bits (79), Expect = 0.11
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 418 QHQTGSHYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
Q Q ++ L + G W + + F +YA +LF GD+V WIT NEP
Sbjct: 1486 QPQVTIYHWDLPQTLQDVGGW--ENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 111 bits (268), Expect = 1e-24
Identities = 47/114 (41%), Positives = 75/114 (65%), Gaps = 3/114 (2%)
Frame = +2
Query: 203 TPGACLRPQQCG---CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNED 373
TPG+ ++ G C S YH D++++ L + YRFS+SW R+ PTG ++ +N
Sbjct: 370 TPGSNVKDNATGDIACDS--YHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSH 427
Query: 374 GLXYYSELLDTLHKNNIKPVVTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
G+ YY+ L++ L +NI P+VT++HWDLPQ+LQD+GGW NP ++D+ + +C
Sbjct: 428 GVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFC 481
Score = 107 bits (257), Expect = 3e-23
Identities = 46/84 (54%), Positives = 58/84 (69%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH D+ + L +S YRFS+SW R+LP G + +NE GL YY L+DTL +I+P
Sbjct: 861 YHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQ 920
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIV 505
VTIYHWDLPQ+LQD+GGW N IV
Sbjct: 921 VTIYHWDLPQTLQDVGGWENETIV 944
Score = 61.7 bits (143), Expect = 2e-09
Identities = 24/53 (45%), Positives = 36/53 (67%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
F F +GV+++++Q+EGAW+ GKG SIWD +TH V D++ D+A DS
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDS 387
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/53 (50%), Positives = 37/53 (69%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
FP+GF + A+A++Q+EGAW GKG SIWD ++H P RV + + DVA DS
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDS 860
Score = 39.5 bits (88), Expect = 0.009
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEPL 588
F YA F TFGDRV W+TFNEP+
Sbjct: 474 FDSYADFCFQTFGDRVKFWMTFNEPM 499
Score = 35.9 bits (79), Expect = 0.11
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 418 QHQTGSHYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
Q Q ++ L + G W + + F +YA +LF GD+V WIT NEP
Sbjct: 918 QPQVTIYHWDLPQTLQDVGGW--ENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 971
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 111 bits (268), Expect = 1e-24
Identities = 47/114 (41%), Positives = 75/114 (65%), Gaps = 3/114 (2%)
Frame = +2
Query: 203 TPGACLRPQQCG---CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNED 373
TPG+ ++ G C S YH D++++ L + YRFS+SW R+ PTG ++ +N
Sbjct: 938 TPGSNVKDNATGDIACDS--YHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSH 995
Query: 374 GLXYYSELLDTLHKNNIKPVVTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
G+ YY+ L++ L +NI P+VT++HWDLPQ+LQD+GGW NP ++D+ + +C
Sbjct: 996 GVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFC 1049
Score = 107 bits (257), Expect = 3e-23
Identities = 46/84 (54%), Positives = 58/84 (69%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH D+ + L +S YRFS+SW R+LP G + +NE GL YY L+DTL +I+P
Sbjct: 1429 YHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQ 1488
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIV 505
VTIYHWDLPQ+LQD+GGW N IV
Sbjct: 1489 VTIYHWDLPQTLQDVGGWENETIV 1512
Score = 96.3 bits (229), Expect = 7e-20
Identities = 39/94 (41%), Positives = 57/94 (60%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
YH DV L+ L Y+FS+SW R+ P G+ + + G+ YY++L+D L I+P+
Sbjct: 433 YHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPM 492
Query: 434 VTIYHWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
T++HWDLPQ+LQD GGW N +VD +C
Sbjct: 493 ATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFC 526
Score = 61.7 bits (143), Expect = 2e-09
Identities = 24/53 (45%), Positives = 36/53 (67%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
F F +GV+++++Q+EGAW+ GKG SIWD +TH V D++ D+A DS
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDS 955
Score = 60.9 bits (141), Expect = 3e-09
Identities = 27/53 (50%), Positives = 37/53 (69%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADS 254
FP+GF + A+A++Q+EGAW GKG SIWD ++H P RV + + DVA DS
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDS 1428
Score = 45.6 bits (103), Expect = 1e-04
Identities = 17/31 (54%), Positives = 22/31 (70%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWD 188
FP+GF +G +T +F VEG W G+G SIWD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 43.6 bits (98), Expect = 5e-04
Identities = 16/25 (64%), Positives = 21/25 (84%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F+DYA F+TFGDRV +W+TF+EP
Sbjct: 519 FLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 39.5 bits (88), Expect = 0.009
Identities = 16/26 (61%), Positives = 18/26 (69%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEPL 588
F YA F TFGDRV W+TFNEP+
Sbjct: 1042 FDSYADFCFQTFGDRVKFWMTFNEPM 1067
Score = 39.1 bits (87), Expect = 0.012
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +2
Query: 299 LSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIYHWDLPQS 466
++ Y+ +SW ++LP G + +E + Y LL L ++P+V ++H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPAS 139
Score = 36.3 bits (80), Expect = 0.083
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNE 582
F DYA F +FGD VG+W TF++
Sbjct: 151 FADYATFAFHSFGDLVGIWFTFSD 174
Score = 35.9 bits (79), Expect = 0.11
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 418 QHQTGSHYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
Q Q ++ L + G W + + F +YA +LF GD+V WIT NEP
Sbjct: 1486 QPQVTIYHWDLPQTLQDVGGW--ENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 105 bits (251), Expect = 2e-22
Identities = 47/98 (47%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +2
Query: 218 LRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSEL 397
L+P S Y+N RD + + EL ++ YRFS+SW RVLP G + + N +GL YY L
Sbjct: 117 LQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRL 176
Query: 398 LDTLHKNNIKPVVTIYHWDLPQSLQD-LGGWTNPIIVD 508
L+ L + ++PVVT+YHWDLPQ LQD GGW N + D
Sbjct: 177 LERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALAD 214
Score = 52.4 bits (120), Expect = 1e-06
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHP 209
FP GF + V +A++Q EG W GKG SIWD +TH HP
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HP 97
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 508 YFVDYARLLFTTFGDRVGVWITFNEP 585
+F DYA L F FG +V WIT + P
Sbjct: 215 HFRDYAELCFRHFGGQVKYWITIDNP 240
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 105 bits (251), Expect = 2e-22
Identities = 47/98 (47%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +2
Query: 218 LRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSEL 397
L+P S Y+N RD + + EL ++ YRFS+SW RVLP G + + N +GL YY L
Sbjct: 117 LQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRL 176
Query: 398 LDTLHKNNIKPVVTIYHWDLPQSLQD-LGGWTNPIIVD 508
L+ L + ++PVVT+YHWDLPQ LQD GGW N + D
Sbjct: 177 LERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALAD 214
Score = 52.4 bits (120), Expect = 1e-06
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHP 209
FP GF + V +A++Q EG W GKG SIWD +TH HP
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HP 97
Score = 51.2 bits (117), Expect = 3e-06
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 275 VDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIY--- 445
+ L+ E+ ++ +RFS+ W +LP G + VN L YY + L + NI PVV ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 446 --HWDLPQSLQDLGGWTNP 496
+ LP+ L G W NP
Sbjct: 642 APNQGLPRLLARQGAWENP 660
Score = 35.1 bits (77), Expect = 0.19
Identities = 14/25 (56%), Positives = 16/25 (64%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F +YARL F G V +WIT NEP
Sbjct: 666 FAEYARLCFQELGHHVKLWITMNEP 690
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 508 YFVDYARLLFTTFGDRVGVWITFNEP 585
+F DYA L F FG +V WIT + P
Sbjct: 215 HFRDYAELCFRHFGGQVKYWITIDNP 240
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 105 bits (251), Expect = 2e-22
Identities = 47/98 (47%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +2
Query: 218 LRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSEL 397
L+P S Y+N RD + + EL ++ YRFS+SW RVLP G + + N +GL YY L
Sbjct: 117 LQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRL 176
Query: 398 LDTLHKNNIKPVVTIYHWDLPQSLQD-LGGWTNPIIVD 508
L+ L + ++PVVT+YHWDLPQ LQD GGW N + D
Sbjct: 177 LERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALAD 214
Score = 52.4 bits (120), Expect = 1e-06
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHP 209
FP GF + V +A++Q EG W GKG SIWD +TH HP
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HP 97
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 508 YFVDYARLLFTTFGDRVGVWITFNEP 585
+F DYA L F FG +V WIT + P
Sbjct: 215 HFRDYAELCFRHFGGQVKYWITIDNP 240
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 105 bits (251), Expect = 2e-22
Identities = 47/98 (47%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +2
Query: 218 LRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSEL 397
L+P S Y+N RD + + EL ++ YRFS+SW RVLP G + + N +GL YY L
Sbjct: 117 LQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRL 176
Query: 398 LDTLHKNNIKPVVTIYHWDLPQSLQD-LGGWTNPIIVD 508
L+ L + ++PVVT+YHWDLPQ LQD GGW N + D
Sbjct: 177 LERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALAD 214
Score = 52.4 bits (120), Expect = 1e-06
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHP 209
FP GF + V +A++Q EG W GKG SIWD +TH HP
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HP 97
Score = 51.2 bits (117), Expect = 3e-06
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 275 VDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIY--- 445
+ L+ E+ ++ +RFS+ W +LP G + VN L YY + L + NI PVV ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 446 --HWDLPQSLQDLGGWTNP 496
+ LP+ L G W NP
Sbjct: 642 APNQGLPRLLARQGAWENP 660
Score = 35.1 bits (77), Expect = 0.19
Identities = 14/25 (56%), Positives = 16/25 (64%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F +YARL F G V +WIT NEP
Sbjct: 666 FAEYARLCFQELGHHVKLWITMNEP 690
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 508 YFVDYARLLFTTFGDRVGVWITFNEP 585
+F DYA L F FG +V WIT + P
Sbjct: 215 HFRDYAELCFRHFGGQVKYWITIDNP 240
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 105 bits (251), Expect = 2e-22
Identities = 47/98 (47%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +2
Query: 218 LRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSEL 397
L+P S Y+N RD + + EL ++ YRFS+SW RVLP G + + N +GL YY L
Sbjct: 117 LQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRL 176
Query: 398 LDTLHKNNIKPVVTIYHWDLPQSLQD-LGGWTNPIIVD 508
L+ L + ++PVVT+YHWDLPQ LQD GGW N + D
Sbjct: 177 LERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALAD 214
Score = 52.4 bits (120), Expect = 1e-06
Identities = 21/38 (55%), Positives = 26/38 (68%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHP 209
FP GF + V +A++Q EG W GKG SIWD +TH HP
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH-HP 97
Score = 51.2 bits (117), Expect = 3e-06
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 275 VDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIY--- 445
+ L+ E+ ++ +RFS+ W +LP G + VN L YY + L + NI PVV ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 446 --HWDLPQSLQDLGGWTNP 496
+ LP+ L G W NP
Sbjct: 642 APNQGLPRLLARQGAWENP 660
Score = 35.1 bits (77), Expect = 0.19
Identities = 14/25 (56%), Positives = 16/25 (64%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F +YARL F G V +WIT NEP
Sbjct: 666 FAEYARLCFQELGHHVKLWITMNEP 690
Score = 31.9 bits (69), Expect = 1.8
Identities = 13/26 (50%), Positives = 16/26 (61%)
Frame = +1
Query: 508 YFVDYARLLFTTFGDRVGVWITFNEP 585
+F DYA L F FG +V WIT + P
Sbjct: 215 HFRDYAELCFRHFGGQVKYWITIDNP 240
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 101 bits (243), Expect = 1e-21
Identities = 45/95 (47%), Positives = 60/95 (63%), Gaps = 1/95 (1%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
Y +D+ + + +SFY+FS+SWPR+ P G + N GL YYS LLD L NI+P+
Sbjct: 131 YIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPI 190
Query: 434 VTIYHWDLPQSLQD-LGGWTNPIIVDILWTTPGYC 535
VT+YHWDLP +LQ+ GGW N I+DI YC
Sbjct: 191 VTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 63.3 bits (147), Expect = 6e-10
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Frame = +2
Query: 200 RTPGACLRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
R G L+ + C + N ++ ++++ + ++ YRF++ W VLPTG + VN L
Sbjct: 563 RVEGVRLKTRPAQCTD--FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQAL 620
Query: 380 XYYSELLDTLHKNNIKPVVTIY-----HWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
YY ++ K I +VT+Y H LP+ L GW NP + G C
Sbjct: 621 RYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 56.4 bits (130), Expect = 7e-08
Identities = 25/55 (45%), Positives = 35/55 (63%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSII 260
FPK F +G+ T + QVEG+W GKG SIWD + H H + V S+ + ++DS I
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYI 132
Score = 35.1 bits (77), Expect = 0.19
Identities = 21/48 (43%), Positives = 23/48 (47%)
Frame = +1
Query: 442 LPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
LPL E G W+ D F DYA F FGDRV WIT + P
Sbjct: 198 LPLALQ-EKYGGWKNDTIID--IFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 31.9 bits (69), Expect = 1.8
Identities = 14/25 (56%), Positives = 15/25 (60%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F YA L F GD V +WIT NEP
Sbjct: 670 FQAYAGLCFQELGDLVKLWITINEP 694
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 101 bits (243), Expect = 1e-21
Identities = 45/95 (47%), Positives = 60/95 (63%), Gaps = 1/95 (1%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
Y +D+ + + +SFY+FS+SWPR+ P G + N GL YYS LLD L NI+P+
Sbjct: 131 YIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPI 190
Query: 434 VTIYHWDLPQSLQD-LGGWTNPIIVDILWTTPGYC 535
VT+YHWDLP +LQ+ GGW N I+DI YC
Sbjct: 191 VTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 63.3 bits (147), Expect = 6e-10
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Frame = +2
Query: 200 RTPGACLRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
R G L+ + C + N ++ ++++ + ++ YRF++ W VLPTG + VN L
Sbjct: 563 RVEGVRLKTRPAQCTD--FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQAL 620
Query: 380 XYYSELLDTLHKNNIKPVVTIY-----HWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
YY ++ K I +VT+Y H LP+ L GW NP + G C
Sbjct: 621 RYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 56.4 bits (130), Expect = 7e-08
Identities = 25/55 (45%), Positives = 35/55 (63%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSII 260
FPK F +G+ T + QVEG+W GKG SIWD + H H + V S+ + ++DS I
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYI 132
Score = 35.1 bits (77), Expect = 0.19
Identities = 21/48 (43%), Positives = 23/48 (47%)
Frame = +1
Query: 442 LPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
LPL E G W+ D F DYA F FGDRV WIT + P
Sbjct: 198 LPLALQ-EKYGGWKNDTIID--IFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 31.9 bits (69), Expect = 1.8
Identities = 14/25 (56%), Positives = 15/25 (60%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F YA L F GD V +WIT NEP
Sbjct: 670 FQAYAGLCFQELGDLVKLWITINEP 694
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 101 bits (243), Expect = 1e-21
Identities = 45/95 (47%), Positives = 60/95 (63%), Gaps = 1/95 (1%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPV 433
Y +D+ + + +SFY+FS+SWPR+ P G + N GL YYS LLD L NI+P+
Sbjct: 131 YIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPI 190
Query: 434 VTIYHWDLPQSLQD-LGGWTNPIIVDILWTTPGYC 535
VT+YHWDLP +LQ+ GGW N I+DI YC
Sbjct: 191 VTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYC 225
Score = 63.3 bits (147), Expect = 6e-10
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Frame = +2
Query: 200 RTPGACLRPQQCGCGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
R G L+ + C + N ++ ++++ + ++ YRF++ W VLPTG + VN L
Sbjct: 563 RVEGVRLKTRPAQCTD--FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQAL 620
Query: 380 XYYSELLDTLHKNNIKPVVTIY-----HWDLPQSLQDLGGWTNPIIVDILWTTPGYC 535
YY ++ K I +VT+Y H LP+ L GW NP + G C
Sbjct: 621 RYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLC 677
Score = 56.4 bits (130), Expect = 7e-08
Identities = 25/55 (45%), Positives = 35/55 (63%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSII 260
FPK F +G+ T + QVEG+W GKG SIWD + H H + V S+ + ++DS I
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNV---SSTNGSSDSYI 132
Score = 35.1 bits (77), Expect = 0.19
Identities = 21/48 (43%), Positives = 23/48 (47%)
Frame = +1
Query: 442 LPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNEP 585
LPL E G W+ D F DYA F FGDRV WIT + P
Sbjct: 198 LPLALQ-EKYGGWKNDTIID--IFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 31.9 bits (69), Expect = 1.8
Identities = 14/25 (56%), Positives = 15/25 (60%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F YA L F GD V +WIT NEP
Sbjct: 670 FQAYAGLCFQELGDLVKLWITINEP 694
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 3e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWLSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.7 bits (81), Expect = 0.062
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWLSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 100 bits (240), Expect = 3e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWLSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.7 bits (81), Expect = 0.062
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWLSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 3e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWLSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.7 bits (81), Expect = 0.062
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWLSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 3e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWLSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.7 bits (81), Expect = 0.062
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWLSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 100 bits (240), Expect = 3e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWLSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.7 bits (81), Expect = 0.062
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWLSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (239), Expect = 4e-21
Identities = 40/90 (44%), Positives = 64/90 (71%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKN 418
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ G+ YY++++D L KN
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKN 110
Query: 419 NIKPVVTIYHWDLPQSLQDLGGWTNPIIVD 508
+ P+VT+YH+DLPQ+L+D GGW + I++
Sbjct: 111 GVTPIVTLYHFDLPQTLEDQGGWWSEAIIE 140
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 36.3 bits (80), Expect = 0.083
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 436 HYLPLGFATEPAGPWRVDQSNHSRYFVDYARLLFTTFGDRVGVWITFNE 582
++ L E G W + S F YA+ F+TFGDRV WIT NE
Sbjct: 119 YHFDLPQTLEDQGGWWSEAIIES--FDKYAQFCFSTFGDRVKQWITINE 165
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 96.7 bits (230), Expect = 6e-20
Identities = 42/82 (51%), Positives = 60/82 (73%), Gaps = 2/82 (2%)
Frame = +2
Query: 254 YHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGY-SNLVNEDGLXYYSELLDTLHKNNIKP 430
Y+ + D+ L+ EL ++ YRFS+SWPR+LPTG + VN+ G+ +YS+L+D L +NI P
Sbjct: 90 YYKVQEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITP 149
Query: 431 VVTIYHWDLPQSLQ-DLGGWTN 493
+VT++HWDLPQ LQ GGW N
Sbjct: 150 IVTLHHWDLPQLLQVKYGGWQN 171
Score = 64.1 bits (149), Expect = 4e-10
Identities = 26/52 (50%), Positives = 35/52 (67%)
Frame = +3
Query: 96 FPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAAD 251
FP GF +GV ++++Q EGAW+ GKG SIWD +TH +V + ADVA D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACD 88
Score = 41.9 bits (94), Expect = 0.002
Identities = 17/28 (60%), Positives = 20/28 (71%)
Frame = +1
Query: 502 SRYFVDYARLLFTTFGDRVGVWITFNEP 585
+ YF DYA L F FGDRV WITF++P
Sbjct: 175 ANYFRDYANLCFEAFGDRVKHWITFSDP 202
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 42.7 bits (96), Expect = 0.001
Identities = 18/47 (38%), Positives = 29/47 (61%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ +
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 70.5 bits (165), Expect = 4e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 42.7 bits (96), Expect = 0.001
Identities = 18/47 (38%), Positives = 29/47 (61%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ +
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 69.7 bits (163), Expect = 7e-12
Identities = 30/69 (43%), Positives = 40/69 (57%)
Frame = +3
Query: 90 LCFPKGFKFGVATASFQVEGAWNVSGKGESIWDRYTHEHPERVFDHSNADVAADSIIISD 269
+ FP GF + ATA++QVEG W+ GKG +WD +TH+ ERVF + DVA S +
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTL-- 58
Query: 270 VTWTSSLNC 296
W L C
Sbjct: 59 --WEEDLKC 65
Score = 42.7 bits (96), Expect = 0.001
Identities = 18/47 (38%), Positives = 29/47 (61%)
Frame = +2
Query: 239 CGSRLYHNFRRDVDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGL 379
CGS Y + D+ + +L L+ YRFS+SW R+LP G + +N+ +
Sbjct: 53 CGS--YTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 51.2 bits (117), Expect = 3e-06
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Frame = +2
Query: 275 VDLVTELSLSFYRFSVSWPRVLPTGYSNLVNEDGLXYYSELLDTLHKNNIKPVVTIY--- 445
+ L+ E+ ++ +RFS+ W +LP G + VN L YY + L + NI PVV ++
Sbjct: 309 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 368
Query: 446 --HWDLPQSLQDLGGWTNP 496
+ LP+ L G W NP
Sbjct: 369 APNQGLPRLLARQGAWENP 387
Score = 35.1 bits (77), Expect = 0.19
Identities = 14/25 (56%), Positives = 16/25 (64%)
Frame = +1
Query: 511 FVDYARLLFTTFGDRVGVWITFNEP 585
F +YARL F G V +WIT NEP
Sbjct: 393 FAEYARLCFQELGHHVKLWITMNEP 417
>AB077881-1|BAB83897.1| 1306|Homo sapiens caspr5 protein.
Length = 1306
Score = 29.9 bits (64), Expect = 7.2
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Frame = +2
Query: 197 PRTPGACLRPQQCGCGSRLYHNFRRDVDLVTELSLSFY----RFSVSWPRVLPTGYSN 358
P PG L+ GC LY+N +DL Y FS S P+++P + N
Sbjct: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVN 372
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,539,816
Number of Sequences: 237096
Number of extensions: 2115157
Number of successful extensions: 6023
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 5429
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6016
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6324506272
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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