Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbS20012
(652 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 171 9e-42
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 155 1e-36
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 150 2e-35
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 148 1e-34
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 147 2e-34
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 136 4e-31
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 128 1e-28
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 122 7e-27
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 109 6e-23
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 83 7e-15
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 60 5e-08
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 53 7e-06
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 52 1e-05
UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5; B... 36 0.84
UniRef50_Q9Y133 Cluster: CG6706-PB, isoform B; n=9; Eumetazoa|Re... 36 1.1
UniRef50_Q3JHI0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141, w... 35 1.5
UniRef50_Q2HCI2 Cluster: Predicted protein; n=1; Chaetomium glob... 35 1.5
UniRef50_Q757T0 Cluster: Probable E3 ubiquitin-protein ligase HU... 35 1.9
UniRef50_Q9H302 Cluster: NADP+-specific isocitrate dehydrogenase... 34 2.6
UniRef50_Q91L92 Cluster: ORF160; n=1; Shrimp white spot syndrome... 34 3.4
UniRef50_Q7S3X3 Cluster: Putative uncharacterized protein NCU022... 34 3.4
UniRef50_Q55ME2 Cluster: Putative uncharacterized protein; n=1; ... 33 5.9
UniRef50_UPI00015B4AD9 Cluster: PREDICTED: similar to sulfate tr... 33 7.8
UniRef50_UPI0000DD7A64 Cluster: PREDICTED: hypothetical protein;... 33 7.8
UniRef50_Q88U08 Cluster: ABC transporter, ATP-binding protein; n... 33 7.8
UniRef50_Q0SI24 Cluster: 3-isopropylmalate dehydrogenase; n=9; B... 33 7.8
UniRef50_A7BWX3 Cluster: Putative uncharacterized protein; n=2; ... 33 7.8
UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 33 7.8
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 171 bits (417), Expect = 9e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 292 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395
Score = 140 bits (340), Expect = 2e-32
Identities = 61/82 (74%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 209 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 268
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F YKT FD+ KIWYEHRLI
Sbjct: 269 IFDKHYKTDFDKNKIWYEHRLI 290
Score = 38.7 bits (86), Expect = 0.12
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 377 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 422
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 155 bits (375), Expect = 1e-36
Identities = 64/84 (76%), Positives = 78/84 (92%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVA A+K GG+VWACKNYDGDVQSD++AQG+GSLG+MTSVL+CPDGRT+E+E+AHGTV
Sbjct: 314 DMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRTIEAEAAHGTV 373
Query: 437 TRHYRMHQQGKPTSTNPVASIYAW 508
TRHYR+HQ+G TSTN +ASI+AW
Sbjct: 374 TRHYRVHQKGGETSTNSIASIFAW 397
Score = 108 bits (260), Expect = 1e-22
Identities = 46/69 (66%), Positives = 59/69 (85%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVA+ MYNTDESI +FA +S +A QK+WPLYLSTKNTILK+YDGRFKDIF+E +++ ++
Sbjct: 220 GVALSMYNTDESIWAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQENYETKWR 279
Query: 210 TKFDEAKIW 236
KFD+A IW
Sbjct: 280 AKFDDAGIW 288
Score = 36.3 bits (80), Expect = 0.64
Identities = 19/45 (42%), Positives = 26/45 (57%)
Frame = +1
Query: 514 GLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHG 648
GL HRAKL + R+ + V ++SGKMTKDL + +HG
Sbjct: 400 GLGHRAKLDDNKRLLDFVQ-KLEAACVGTVESGKMTKDLALLVHG 443
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 150 bits (364), Expect = 2e-35
Identities = 62/84 (73%), Positives = 77/84 (91%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVA A+K GG+VWACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 253 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAW 508
TRH+R+HQ+G TSTN +ASI+AW
Sbjct: 313 TRHFRVHQKGGETSTNSIASIFAW 336
Score = 128 bits (308), Expect = 2e-28
Identities = 55/75 (73%), Positives = 66/75 (88%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAM MYNTDESIR+FA +S A +KKWPLYLSTKNTILK+YDGRFKDIF+EV+++ +K
Sbjct: 177 GVAMAMYNTDESIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWK 236
Query: 210 TKFDEAKIWYEHRLI 254
+K+D A IWYEHRLI
Sbjct: 237 SKYDAAGIWYEHRLI 251
Score = 40.3 bits (90), Expect = 0.039
Identities = 21/46 (45%), Positives = 29/46 (63%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHG 648
RGLAHRAKL ++++ + V ++SGKMTKDL + IHG
Sbjct: 338 RGLAHRAKLDDNAKLLDFTE-KLEAACVGTVESGKMTKDLALIIHG 382
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 148 bits (358), Expect = 1e-34
Identities = 69/104 (66%), Positives = 79/104 (75%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ IK GGF+ A KNYDGDVQSDIVAQG+GSLG+MTS L PDG ESE+AHGTV
Sbjct: 308 DMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLTTPDGSAFESEAAHGTV 367
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+ TSTNP+ASI+AW L D TP++ FA
Sbjct: 368 TRHYREHQKGRETSTNPIASIFAWTRGLVQRGQLDNTPDVVTFA 411
Score = 130 bits (314), Expect = 3e-29
Identities = 58/94 (61%), Positives = 77/94 (81%), Gaps = 1/94 (1%)
Frame = +3
Query: 9 LYDFKTPG-VAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFE 185
+YDF++ G VAM MYNTD+SIR FAHSSF++AL K PLY+STKNTILKRYDGRFKDIF+
Sbjct: 224 VYDFQSGGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTKNTILKRYDGRFKDIFQ 283
Query: 186 EVFQSDYKTKFDEAKIWYEHRLITTWWHRLLRDQ 287
E+++++YK +FD IWYEHRLI ++++ +
Sbjct: 284 EIYEAEYKKEFDAKGIWYEHRLIDDMVAQMIKSE 317
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 147 bits (356), Expect = 2e-34
Identities = 65/103 (63%), Positives = 82/103 (79%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVA A+K GG+VWACKNYDGDVQSD++AQG+GSLG+MTSVL+ DG+T+ESE+AHGTV
Sbjct: 324 DMVAYAVKSEGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSADGKTLESEAAHGTV 383
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERF 565
TRH+R+HQ+G+ TSTN +ASI+AW L D +L F
Sbjct: 384 TRHFRLHQKGQETSTNSIASIFAWTRGLEHRAKLDKNEKLMDF 426
Score = 139 bits (336), Expect = 6e-32
Identities = 60/82 (73%), Positives = 72/82 (87%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+YDFK PGVA+ MYN DESIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+E
Sbjct: 241 VYDFKGPGVALAMYNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQE 300
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
V+++++K KF+E IWYEHRLI
Sbjct: 301 VYEANWKQKFEEHSIWYEHRLI 322
Score = 38.7 bits (86), Expect = 0.12
Identities = 19/46 (41%), Positives = 28/46 (60%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHG 648
RGL HRAKL ++ ++ + V +++GKMTKDL + IHG
Sbjct: 409 RGLEHRAKLDKNEKLMDFVK-KLESSCVNTVETGKMTKDLALLIHG 453
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 136 bits (329), Expect = 4e-31
Identities = 59/82 (71%), Positives = 70/82 (85%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+FK PGVA+ MYN DESIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+E
Sbjct: 44 VYNFKGPGVALSMYNVDESIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQE 103
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
V++ +K KF+E IWYEHRLI
Sbjct: 104 VYEEKWKEKFEENSIWYEHRLI 125
Score = 91.5 bits (217), Expect = 2e-17
Identities = 40/58 (68%), Positives = 49/58 (84%)
Frame = +3
Query: 60 ESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
+SIR+FA SS +AL KKWPLYLSTKNTILK+YDGRFKDIF+EV++ +K KF+E I
Sbjct: 157 QSIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQEVYEEKWKEKFEENSI 214
Score = 59.7 bits (138), Expect = 6e-08
Identities = 24/31 (77%), Positives = 27/31 (87%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQ 349
DMVA A+K GG+VWACKNYDGDVQSD +AQ
Sbjct: 127 DMVAYAVKSEGGYVWACKNYDGDVQSDFLAQ 157
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 128 bits (309), Expect = 1e-28
Identities = 60/104 (57%), Positives = 73/104 (70%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
D+VA+ +K GGF+WACKNYDGDV SD+V+ +GSL MMTSVL+ P G E E+AHGTV
Sbjct: 266 DIVARVMKAEGGFIWACKNYDGDVMSDMVSSAFGSLAMMTSVLVSPQG-YYEYEAAHGTV 324
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
RHY H +GK TSTN VA+I+AW L DG +LE FA
Sbjct: 325 QRHYYRHLEGKETSTNSVATIFAWTGALRKRGELDGNQKLEEFA 368
Score = 85.8 bits (203), Expect = 8e-16
Identities = 38/83 (45%), Positives = 56/83 (67%)
Frame = +3
Query: 6 VLYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFE 185
++ +FK PGVAMGM+N SI SFA S F AL K ++ K+TI K YD +FK++F+
Sbjct: 182 LVQEFKAPGVAMGMHNMTASIESFARSCFNYALDTKQDVWFGAKDTISKTYDAKFKEVFQ 241
Query: 186 EVFQSDYKTKFDEAKIWYEHRLI 254
VF +++K +F+EA + Y + LI
Sbjct: 242 TVFDTEFKDRFEEAGLTYFYSLI 264
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 122 bits (294), Expect = 7e-27
Identities = 57/104 (54%), Positives = 72/104 (69%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
D VA+ +K GGF+WACKNYDGDV SD+VA +GSL MMTSVL+ P+G E E+AHGTV
Sbjct: 252 DAVARVVKSEGGFIWACKNYDGDVMSDMVATAFGSLAMMTSVLVSPEG-YYEYEAAHGTV 310
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
+HY H +G+ TSTN +A+++AW L DG EL FA
Sbjct: 311 QKHYYQHLKGQLTSTNSMATLFAWTGALRKRGEIDGINELVEFA 354
Score = 88.2 bits (209), Expect = 1e-16
Identities = 42/95 (44%), Positives = 62/95 (65%)
Frame = +3
Query: 3 RVLYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIF 182
+ L+ F PGV MGM+N D+SI SFA S F AL L+ ++K+TI K YD RFKDIF
Sbjct: 167 QTLHVFNGPGVVMGMHNLDKSIESFARSCFNYALDMNQNLWFASKDTISKTYDHRFKDIF 226
Query: 183 EEVFQSDYKTKFDEAKIWYEHRLITTWWHRLLRDQ 287
+E++ ++Y KF++A I Y + LI R+++ +
Sbjct: 227 QEIYDTEYDAKFNDAGIEYFYTLIDDAVARVVKSE 261
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 109 bits (262), Expect = 6e-23
Identities = 47/67 (70%), Positives = 57/67 (85%)
Frame = +3
Query: 54 TDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
TDESI SFA +S A +KKWPLYLSTKNTILK+YDGRFKDIF+EV++ +K+K++ A I
Sbjct: 1 TDESIYSFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEKSWKSKYEAAGI 60
Query: 234 WYEHRLI 254
WYEHRLI
Sbjct: 61 WYEHRLI 67
Score = 52.0 bits (119), Expect = 1e-05
Identities = 21/34 (61%), Positives = 26/34 (76%)
Frame = +2
Query: 419 SAHGTVTRHYRMHQQGKPTSTNPVASIYAWQEVL 520
+AHG VTRHYR+HQ+G STN +ASI+AW L
Sbjct: 123 AAHGAVTRHYRVHQKGGEASTNSIASIFAWSRGL 156
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 82.6 bits (195), Expect = 7e-15
Identities = 42/85 (49%), Positives = 51/85 (60%)
Frame = -1
Query: 508 PGVDRSDRVSGCRLALLVHTVVTCHRPVRRFGFHGTAIGTHQY*CHHSQ*PVTLSNNIGL 329
PG+DR D V G RLALLV TV+ HR VRR H AI HQ HH Q P L + + L
Sbjct: 120 PGIDRRDGVGGGRLALLVLTVMARHRAVRRLRLHDPAIRRHQLRGHHPQRPEALRHRVRL 179
Query: 328 HISVVVFAGPNKAT*SLNSLCHHVV 254
H++V+V AGP++ L HHVV
Sbjct: 180 HVAVIVLAGPDELAVPLERAGHHVV 204
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/69 (37%), Positives = 39/69 (56%)
Frame = -3
Query: 245 MLVPYLGFIKLSLVVTLKNFFENVFETTIVTFQNGILRRQV*RPFFL*SYLKTGMGKGPN 66
+LVP ++L + L + E V E +V +NG+L RQV RP + ++ G GK +
Sbjct: 208 VLVPDALRLELLGKLRLVDLLEQVLEPPVVGLENGVLGRQVHRPAQRQTVVQRGAGKVAD 267
Query: 65 RFVGIVHAH 39
R V +VHAH
Sbjct: 268 RLVLVVHAH 276
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 60.1 bits (139), Expect = 5e-08
Identities = 36/85 (42%), Positives = 46/85 (54%)
Frame = -1
Query: 508 PGVDRSDRVSGCRLALLVHTVVTCHRPVRRFGFHGTAIGTHQY*CHHSQ*PVTLSNNIGL 329
PG DR +RV L LL+ T+V HR + FGF AIG Q H + L + IGL
Sbjct: 89 PGEDRCNRVRRGFLTLLMLTIVAGHRTMSGFGFDRLAIGRQQNRGHQPERAEALRDGIGL 148
Query: 328 HISVVVFAGPNKAT*SLNSLCHHVV 254
++VVV AGP+ A+ L HVV
Sbjct: 149 DVAVVVLAGPDVASGPLQGRGDHVV 173
Score = 56.4 bits (130), Expect = 6e-07
Identities = 29/78 (37%), Positives = 46/78 (58%)
Frame = -3
Query: 248 TMLVPYLGFIKLSLVVTLKNFFENVFETTIVTFQNGILRRQV*RPFFL*SYLKTGMGKGP 69
T+ V GF++L L L +F E+V E ++ ++G+L RQV RPF + G G+
Sbjct: 176 TVFVGDPGFLELILEFGLVDFLEDVLEAAVIGLEDGVLGRQVDRPFAHQAVHHRGAGEFA 235
Query: 68 NRFVGIVHAHSNARSFKI 15
+RFV +VH H NA + ++
Sbjct: 236 DRFVEVVHGHGNAGARRV 253
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +3
Query: 51 NTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAK 230
N ++++AH FQ A+ +K YL K+T++ YDG + E +++ +YK +F+
Sbjct: 195 NDIADVKAWAHRFFQRAIDEKRDAYLGLKDTVIAGYDGVMRAAIEAIYKQEYKKQFEAVG 254
Query: 231 IWYEHRLITTWWHRLLRD--QVALFGPAKTTT 320
I Y + L+ R++ + + AL+G TT
Sbjct: 255 INYYYELVDAQAARIVANPPERALWGVPDNTT 286
Score = 41.9 bits (94), Expect = 0.013
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 296 VWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTVTRHY--RMHQQGK 469
++ +N DGD+ SDI A GSL +S++ T+ E+ HGT Y + GK
Sbjct: 440 LYPAQNLDGDIFSDISAALGGSLATASSIIESKSS-TMLFEAPHGTAHDLYLKYLESNGK 498
Query: 470 PTSTNPVASIYAWQEVLHT 526
NP A IYA L T
Sbjct: 499 DAHFNPSALIYALANALET 517
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Frame = +2
Query: 287 GGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVL--MCPDGRTV-ESESAHGTVTRHYRMH 457
GGF A NYDGDV +D +AQ + S G +TS L + DG + E E++HGTV
Sbjct: 290 GGFGMAAHNYDGDVLTDELAQVHKSPGFITSNLVGVHEDGTLIKEFEASHGTVADMDEAR 349
Query: 458 QQGKPTSTNPVASI 499
+G+ TS NP+ +
Sbjct: 350 LRGEETSLNPLGMV 363
>UniRef50_Q67N12 Cluster: 3-isopropylmalate dehydrogenase; n=5;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Symbiobacterium thermophilum
Length = 357
Score = 35.9 bits (79), Expect = 0.84
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Frame = +2
Query: 305 CKNYDGDVQSDIVAQGYGSLGMMTSVLMCPD----GRTVESESAHGT 433
C N DGD+ SD+V YGS+ S+L+ D R V +E+ HGT
Sbjct: 230 CLNRDGDILSDLVLALYGSIAGSESLLIAFDEQFNPRVVMAEAPHGT 276
>UniRef50_Q9Y133 Cluster: CG6706-PB, isoform B; n=9; Eumetazoa|Rep:
CG6706-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 1221
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/67 (29%), Positives = 32/67 (47%)
Frame = +2
Query: 335 DIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTVTRHYRMHQQGKPTSTNPVASIYAWQE 514
D V Y G+M SV + G E HG + +YR+H T N + ++ +
Sbjct: 41 DGVENSYTGRGVMPSVKLAL-GHVNE----HGKILANYRLHMWWNDTQCNAAVGVKSFFD 95
Query: 515 VLHTGPN 535
++H+GPN
Sbjct: 96 MMHSGPN 102
>UniRef50_Q3JHI0 Cluster: Putative uncharacterized protein; n=1;
Burkholderia pseudomallei 1710b|Rep: Putative
uncharacterized protein - Burkholderia pseudomallei
(strain 1710b)
Length = 736
Score = 35.1 bits (77), Expect = 1.5
Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 400 PYRGIRIGARDGDTSLPYA-PARQADIH*PGRFYLRLARGLAHRAKLGRDSRIGALRS*P 576
P+ + + +R P+A PA + PGR +RL G+ RA+ GR+ R+ A R+ P
Sbjct: 6 PHPCVPLASRTAGGEAPHAAPAGRGRRVLPGRRTIRLCMGVVRRAR-GRERRLRAGRAVP 64
Query: 577 SKRRXVECIDSGK 615
+ RR I +G+
Sbjct: 65 AARRRPAEIHAGQ 77
>UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_141,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 490
Score = 35.1 bits (77), Expect = 1.5
Identities = 18/61 (29%), Positives = 32/61 (52%)
Frame = +3
Query: 36 AMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTK 215
++ + ++ I + H SF++ L K +STKN ++ Y+G + FE Q D+K
Sbjct: 101 SLSIITSNNIINQWRHYSFKLPLPKLNNQDVSTKNQKIRAYNGSYSINFESTQQRDFKYV 160
Query: 216 F 218
F
Sbjct: 161 F 161
>UniRef50_Q2HCI2 Cluster: Predicted protein; n=1; Chaetomium
globosum|Rep: Predicted protein - Chaetomium globosum
(Soil fungus)
Length = 673
Score = 35.1 bits (77), Expect = 1.5
Identities = 15/28 (53%), Positives = 22/28 (78%)
Frame = -2
Query: 645 VYTNNQIFCHFTAIDALDXTPLRGLRAK 562
+Y++NQ FCH+ A+ +L +PLR LRAK
Sbjct: 81 LYSSNQFFCHYEALHSL--SPLRDLRAK 106
>UniRef50_Q757T0 Cluster: Probable E3 ubiquitin-protein ligase HUL4;
n=1; Eremothecium gossypii|Rep: Probable E3
ubiquitin-protein ligase HUL4 - Ashbya gossypii (Yeast)
(Eremothecium gossypii)
Length = 839
Score = 34.7 bits (76), Expect = 1.9
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 3/43 (6%)
Frame = +3
Query: 120 LYLSTKNTILK--RYDGR-FKDIFEEVFQSDYKTKFDEAKIWY 239
LY T +LK YDG F+DIF F++ + +FDE+KI Y
Sbjct: 614 LYPETGTNMLKMLEYDGEDFEDIFALTFETCFPDRFDESKIHY 656
>UniRef50_Q9H302 Cluster: NADP+-specific isocitrate dehydrogenase;
n=1; Homo sapiens|Rep: NADP+-specific isocitrate
dehydrogenase - Homo sapiens (Human)
Length = 127
Score = 34.3 bits (75), Expect = 2.6
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLA RAK + + + + +E I++G MTKDL CI GL
Sbjct: 16 RGLALRAKTDNNKELAFFAN-ALEEVCIETIEAGFMTKDLAACIKGL 61
>UniRef50_Q91L92 Cluster: ORF160; n=1; Shrimp white spot syndrome
virus|Rep: ORF160 - White spot syndrome virus (WSSV)
Length = 786
Score = 33.9 bits (74), Expect = 3.4
Identities = 19/55 (34%), Positives = 29/55 (52%)
Frame = +3
Query: 60 ESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDE 224
+SIR F S Q +QK+W ++ N ++ YDG EE+F+ YK +E
Sbjct: 702 QSIRKFIGESMQ-HVQKEWSSAVNNGNRGVENYDGLNAQFSEELFELLYKLIIEE 755
>UniRef50_Q7S3X3 Cluster: Putative uncharacterized protein
NCU02216.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU02216.1 - Neurospora crassa
Length = 493
Score = 33.9 bits (74), Expect = 3.4
Identities = 21/79 (26%), Positives = 35/79 (44%)
Frame = +2
Query: 281 GSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTVTRHYRMHQ 460
G+ G+ W YDGDV + Q +L T+ L+ T E E+ VT +
Sbjct: 383 GTCGYRWNVGKYDGDVSNGPAGQEMSALAAFTTYLI-----TEEHEAVKPLVTNNTGGQS 437
Query: 461 QGKPTSTNPVASIYAWQEV 517
+G P + A++ + E+
Sbjct: 438 RGNPNAGGTPATVMSMSEL 456
>UniRef50_Q55ME2 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 529
Score = 33.1 bits (72), Expect = 5.9
Identities = 16/36 (44%), Positives = 20/36 (55%)
Frame = +2
Query: 290 GFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPD 397
G ACKN DGD + + +G S M TS L+ PD
Sbjct: 52 GTTMACKNEDGDEEEEADVEGILSPTMDTSTLLSPD 87
>UniRef50_UPI00015B4AD9 Cluster: PREDICTED: similar to sulfate
transporter; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to sulfate transporter - Nasonia vitripennis
Length = 714
Score = 32.7 bits (71), Expect = 7.8
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Frame = +2
Query: 230 DMVRASFNYDMVAQAIKGSGGFVWACK-NYDGDVQSDIVAQGYGSL 364
D++ SF MV+ I S ++A K NYD D +++AQG G+L
Sbjct: 333 DIILDSFVITMVSYTISMSMALIFAQKLNYDVDSNQELMAQGLGNL 378
>UniRef50_UPI0000DD7A64 Cluster: PREDICTED: hypothetical protein;
n=2; Euarchontoglires|Rep: PREDICTED: hypothetical
protein - Homo sapiens
Length = 239
Score = 32.7 bits (71), Expect = 7.8
Identities = 15/32 (46%), Positives = 22/32 (68%)
Frame = +1
Query: 436 DTSLPYAPARQADIH*PGRFYLRLARGLAHRA 531
D+++P AP QA+ H P R R ARGL+H++
Sbjct: 155 DSAIPKAPCAQANSHPPRRTSPRGARGLSHQS 186
>UniRef50_Q88U08 Cluster: ABC transporter, ATP-binding protein; n=2;
Lactobacillus|Rep: ABC transporter, ATP-binding protein
- Lactobacillus plantarum
Length = 292
Score = 32.7 bits (71), Expect = 7.8
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +2
Query: 317 DGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTVTRHY 448
DGDV +DI+ Q Y G T V DG + + G +T HY
Sbjct: 209 DGDV-TDILGQSYAVTGPQTDVSTYTDGLNIIGKDHLGGITAHY 251
>UniRef50_Q0SI24 Cluster: 3-isopropylmalate dehydrogenase; n=9;
Bacteria|Rep: 3-isopropylmalate dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 365
Score = 32.7 bits (71), Expect = 7.8
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +3
Query: 24 TPGVAMGM-YNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQS 200
TP VA+ + T ++ AH++F +A + + + K +L G F+D+ EV Q
Sbjct: 156 TPDVALAVGVVTRKACERIAHTAFALARTRGRHVTIVHKANVLSMTTGLFRDVCREVGQR 215
Query: 201 DY 206
DY
Sbjct: 216 DY 217
>UniRef50_A7BWX3 Cluster: Putative uncharacterized protein; n=2;
Beggiatoa|Rep: Putative uncharacterized protein -
Beggiatoa sp. PS
Length = 461
Score = 32.7 bits (71), Expect = 7.8
Identities = 14/38 (36%), Positives = 19/38 (50%)
Frame = +3
Query: 453 CTSKASRHPLTRSLLSTPGKRSCTPGQIRTGLQNWSAS 566
CTS R PL + L+ P + +C PG QNW +
Sbjct: 84 CTSNPQRQPLAGTCLADP-ENTCLPGPKENNSQNWQGN 120
>UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG06736 - Caenorhabditis
briggsae
Length = 394
Score = 32.7 bits (71), Expect = 7.8
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Frame = +3
Query: 54 TDESIRSFAHSSFQVALQKKWPLYLSTKNTILKR----YDGRFKDIFEEVFQSDYKTKFD 221
TD +++ F+H A + LY T N + K + +F +I+E FQ+ + T FD
Sbjct: 81 TDPNLK-FSHLG---ACKANLTLYEQTLNKLWKPNTCFVNSKFAEIYESPFQNVFLTLFD 136
Query: 222 EAKIWYEHRL 251
+W +RL
Sbjct: 137 NGTVWVNYRL 146
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 718,820,835
Number of Sequences: 1657284
Number of extensions: 15587938
Number of successful extensions: 41615
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 39885
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41597
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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