Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fbS20012
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 171 1e-42
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 171 1e-42
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 171 1e-42
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 171 1e-42
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 171 1e-42
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 167 4e-41
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 165 9e-41
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 165 9e-41
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 165 9e-41
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 165 9e-41
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 165 9e-41
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 165 9e-41
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 165 9e-41
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 165 9e-41
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 161 1e-39
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 131 2e-30
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 34 0.38
BC030775-1|AAH30775.1| 941|Homo sapiens ARTS-1 protein protein. 32 2.0
AY358590-1|AAQ88953.1| 941|Homo sapiens ARTS-1 protein. 32 2.0
AY028807-1|AAK37778.1| 948|Homo sapiens adipocyte-derived leuci... 32 2.0
AY028806-1|AAK37777.1| 948|Homo sapiens adipocyte-derived leuci... 32 2.0
AF222340-1|AAF34664.1| 941|Homo sapiens type 1 tumor necrosis f... 32 2.0
AF183569-1|AAF20384.1| 941|Homo sapiens aminopeptidase PILS pro... 32 2.0
AF106037-1|AAF07395.1| 941|Homo sapiens adipocyte-derived leuci... 32 2.0
AB011097-1|BAA25451.2| 951|Homo sapiens KIAA0525 protein protein. 32 2.0
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 171 bits (417), Expect = 1e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 292 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395
Score = 140 bits (340), Expect = 3e-33
Identities = 61/82 (74%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 209 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 268
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F YKT FD+ KIWYEHRLI
Sbjct: 269 IFDKHYKTDFDKNKIWYEHRLI 290
Score = 38.7 bits (86), Expect = 0.018
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 377 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 422
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 171 bits (417), Expect = 1e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 259 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 318
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 319 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 362
Score = 140 bits (340), Expect = 3e-33
Identities = 61/82 (74%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 176 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 235
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F YKT FD+ KIWYEHRLI
Sbjct: 236 IFDKHYKTDFDKNKIWYEHRLI 257
Score = 38.7 bits (86), Expect = 0.018
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 344 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 389
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 171 bits (417), Expect = 1e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 292 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395
Score = 140 bits (340), Expect = 3e-33
Identities = 61/82 (74%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 209 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 268
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F YKT FD+ KIWYEHRLI
Sbjct: 269 IFDKHYKTDFDKNKIWYEHRLI 290
Score = 38.7 bits (86), Expect = 0.018
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 377 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 422
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 171 bits (417), Expect = 1e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 292 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395
Score = 140 bits (340), Expect = 3e-33
Identities = 61/82 (74%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 209 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 268
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F YKT FD+ KIWYEHRLI
Sbjct: 269 IFDKHYKTDFDKNKIWYEHRLI 290
Score = 38.7 bits (86), Expect = 0.018
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 377 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 422
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 171 bits (417), Expect = 1e-42
Identities = 75/104 (72%), Positives = 89/104 (85%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQ +K SGGFVWACKNYDGDVQSDI+AQG+GSLG+MTSVL+CPDG+T+E+E+AHGTV
Sbjct: 292 DMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYR HQ+G+PTSTNP+ASI+AW L DG +L RFA
Sbjct: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395
Score = 139 bits (336), Expect = 9e-33
Identities = 60/82 (73%), Positives = 68/82 (82%)
Frame = +3
Query: 9 LYDFKTPGVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEE 188
+Y+F GV MGMYNTDESI FAHS FQ A+QKKWPLY+STKNTILK YDGRFKDIF+E
Sbjct: 209 VYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQE 268
Query: 189 VFQSDYKTKFDEAKIWYEHRLI 254
+F Y+T FD+ KIWYEHRLI
Sbjct: 269 IFDKHYETDFDKNKIWYEHRLI 290
Score = 38.7 bits (86), Expect = 0.018
Identities = 21/47 (44%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGL HR KL + + ++ VE ++SG MTKDL CIHGL
Sbjct: 377 RGLEHRGKLDGNQDLIRFAQ-MLEKVCVETVESGAMTKDLAGCIHGL 422
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 167 bits (405), Expect = 4e-41
Identities = 76/104 (73%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+ESAHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 224 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 283
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 284 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 327
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 148 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 207
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 208 SQFEAQKIWYEHRLI 222
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 309 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 354
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 37.9 bits (84), Expect = 0.031
Identities = 20/47 (42%), Positives = 27/47 (57%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTK L CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKGLAACIKGL 383
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 165 bits (402), Expect = 9e-41
Identities = 75/104 (72%), Positives = 86/104 (82%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTNP+ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIKGL 383
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 161 bits (392), Expect = 1e-39
Identities = 74/104 (71%), Positives = 85/104 (81%)
Frame = +2
Query: 257 DMVAQAIKGSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLMCPDGRTVESESAHGTV 436
DMVAQA+K GGF+WACKNYDGDVQSD VAQGYGSLGMMTSVL+CPDG+TVE+E+AHGTV
Sbjct: 253 DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTV 312
Query: 437 TRHYRMHQQGKPTSTNPVASIYAWQEVLHTGPN*DGTPELERFA 568
TRHYRM+Q+G+ TSTN +ASI+AW L D EL FA
Sbjct: 313 TRHYRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFA 356
Score = 129 bits (311), Expect = 1e-29
Identities = 56/75 (74%), Positives = 64/75 (85%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK YDGRFKDIF+E++ YK
Sbjct: 177 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYK 236
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 237 SQFEAQKIWYEHRLI 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 21/47 (44%), Positives = 28/47 (59%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLAHRAKL + + + + +E I++G MTKDL CI GL
Sbjct: 338 RGLAHRAKLDNNKELAFFAN-ALEEVSIETIEAGFMTKDLAACIRGL 383
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 131 bits (316), Expect = 2e-30
Identities = 56/75 (74%), Positives = 65/75 (86%)
Frame = +3
Query: 30 GVAMGMYNTDESIRSFAHSSFQVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYK 209
GVAMGMYN D+SI FAHSSFQ+AL K WPLYLSTKNTILK+YDGRFKDIF+E++ YK
Sbjct: 78 GVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYK 137
Query: 210 TKFDEAKIWYEHRLI 254
++F+ KIWYEHRLI
Sbjct: 138 SQFEAQKIWYEHRLI 152
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 34.3 bits (75), Expect = 0.38
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = +1
Query: 511 RGLAHRAKLGRDSRIGALRS*PSKRRXVECIDSGKMTKDLVICIHGL 651
RGLA RAK + + + + +E I++G MTKDL CI GL
Sbjct: 16 RGLALRAKTDNNKELAFFAN-ALEEVCIETIEAGFMTKDLAACIKGL 61
Score = 30.3 bits (65), Expect = 6.2
Identities = 15/31 (48%), Positives = 17/31 (54%)
Frame = +2
Query: 476 STNPVASIYAWQEVLHTGPN*DGTPELERFA 568
STNP+ASI+AW L D EL FA
Sbjct: 4 STNPIASIFAWTRGLALRAKTDNNKELAFFA 34
>BC030775-1|AAH30775.1| 941|Homo sapiens ARTS-1 protein protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY358590-1|AAQ88953.1| 941|Homo sapiens ARTS-1 protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY028807-1|AAK37778.1| 948|Homo sapiens adipocyte-derived leucine
aminopeptidase 2 isoform b protein.
Length = 948
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AY028806-1|AAK37777.1| 948|Homo sapiens adipocyte-derived leucine
aminopeptidase 2 isoform a protein.
Length = 948
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF222340-1|AAF34664.1| 941|Homo sapiens type 1 tumor necrosis
factor receptor shedding aminopeptidase regulator
protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF183569-1|AAF20384.1| 941|Homo sapiens aminopeptidase PILS
protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AF106037-1|AAF07395.1| 941|Homo sapiens adipocyte-derived leucine
aminopeptidase protein.
Length = 941
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 130 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 176
>AB011097-1|BAA25451.2| 951|Homo sapiens KIAA0525 protein protein.
Length = 951
Score = 31.9 bits (69), Expect = 2.0
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +3
Query: 93 QVALQKKWPLYLSTKNTILKRYDGRFKDIFEEVFQSDYKTKFDEAKI 233
Q+AL PL + T++ Y G + F ++S Y+TK E +I
Sbjct: 133 QIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRI 179
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,053,681
Number of Sequences: 237096
Number of extensions: 2449923
Number of successful extensions: 5367
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 4866
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5357
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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