Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31945
(516 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VNX4 Cluster: CG7145-PA, isoform A; n=4; Diptera|Rep:... 253 2e-66
UniRef50_UPI00006A1A38 Cluster: Delta-1-pyrroline-5-carboxylate ... 171 8e-42
UniRef50_Q8T0Q8 Cluster: GH13449p; n=4; Sophophora|Rep: GH13449p... 170 1e-41
UniRef50_P30038 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 169 3e-41
UniRef50_P0C2X9 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 167 1e-40
UniRef50_Q5BVL1 Cluster: SJCHGC02702 protein; n=2; Schistosoma j... 162 4e-39
UniRef50_Q9NKR5 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 148 9e-35
UniRef50_Q9P8I0 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 138 5e-32
UniRef50_A1DMS3 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 134 1e-30
UniRef50_Q0BZR5 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 133 3e-30
UniRef50_Q8CJR1 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 128 1e-28
UniRef50_P07275 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 126 4e-28
UniRef50_A1WRX5 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 124 9e-28
UniRef50_Q2PIP5 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 113 2e-24
UniRef50_Q5B0A8 Cluster: Putative uncharacterized protein; n=1; ... 112 4e-24
UniRef50_Q2J962 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 111 1e-23
UniRef50_Q4T8X0 Cluster: Chromosome undetermined SCAF7712, whole... 98 1e-19
UniRef50_UPI0000E4A52D Cluster: PREDICTED: hypothetical protein;... 91 1e-17
UniRef50_Q95TY8 Cluster: GH20963p; n=1; Drosophila melanogaster|... 76 4e-13
UniRef50_Q4JC93 Cluster: Aldehyde dehydrogenase; n=2; Sulfolobac... 58 9e-08
UniRef50_Q83DR6 Cluster: Proline dehydrogenase/delta-1-pyrroline... 54 1e-06
UniRef50_Q082D7 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 50 3e-05
UniRef50_Q703Z2 Cluster: Aldehyde dehydrogenase; n=1; Thermoprot... 49 7e-05
UniRef50_UPI00015BD0F0 Cluster: UPI00015BD0F0 related cluster; n... 47 2e-04
UniRef50_Q9HKJ5 Cluster: Aldehyde dehydrogenase related protein;... 47 2e-04
UniRef50_A4Z2X8 Cluster: Bifunctional putA protein: proline dehy... 46 5e-04
UniRef50_Q97D25 Cluster: NADP-dependent glyceraldehyde-3-phospha... 45 0.001
UniRef50_Q1AXK7 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacte... 44 0.002
UniRef50_O24897 Cluster: Delta-1-pyrroline-5-carboxylate dehydro... 43 0.005
UniRef50_A3WI91 Cluster: Succinate-semialdehyde dehydrogenase (N... 42 0.006
UniRef50_Q9K9B2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 42 0.006
UniRef50_Q21J80 Cluster: Aldehyde dehydrogenase; n=1; Saccharoph... 42 0.008
UniRef50_Q0S1Y5 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcu... 42 0.008
UniRef50_A3WGW3 Cluster: PutA; n=17; Proteobacteria|Rep: PutA - ... 40 0.025
UniRef50_Q8XHP4 Cluster: NADP-dependent glyceraldehyde-3-phospha... 40 0.034
UniRef50_Q62BD6 Cluster: Methylmalonate-semialdehyde dehydrogena... 40 0.034
UniRef50_Q39NZ7 Cluster: Succinic semialdehyde dehydrogenase; n=... 40 0.045
UniRef50_A5WEU6 Cluster: Aldehyde dehydrogenase; n=13; Proteobac... 40 0.045
UniRef50_A3V8Q9 Cluster: Succinate-semialdehyde dehydrogenase; n... 40 0.045
UniRef50_Q8Y8I9 Cluster: Lmo0913 protein; n=11; Listeria|Rep: Lm... 39 0.059
UniRef50_Q9Z672 Cluster: Succinic semialdehyde dehydrogenase; n=... 39 0.078
UniRef50_Q7Z1Q3 Cluster: Aldehyde dehydrogenase protein 12, isof... 39 0.078
UniRef50_Q7WBK1 Cluster: Probable aldehyde dehydrogenase; n=2; B... 38 0.10
UniRef50_Q8U2S5 Cluster: Non-phosphorylating glyceraldehyde-3-ph... 38 0.10
UniRef50_A6GKH6 Cluster: Succinate-semialdehyde dehydrogenase (N... 38 0.18
UniRef50_A1RDQ2 Cluster: Aldehyde dehydrogenase; n=4; Actinobact... 37 0.24
UniRef50_Q75TD2 Cluster: Aldehyde dehydrogenase family; n=14; Ba... 37 0.31
UniRef50_O66573 Cluster: Aldehyde dehydrogenase; n=1; Aquifex ae... 36 0.41
UniRef50_Q97BQ6 Cluster: Betaine aldehyde dehydrogenase; n=2; Th... 36 0.41
UniRef50_Q13XQ3 Cluster: Aldehyde dehydrogenase; n=7; Burkholder... 36 0.72
UniRef50_Q9URW9 Cluster: Aldehyde dehydrogenase; n=20; Ascomycot... 36 0.72
UniRef50_Q1IRG5 Cluster: Methylmalonate-semialdehyde dehydrogena... 35 0.96
UniRef50_A0QUC9 Cluster: Aldehyde dehydrogenase; n=1; Mycobacter... 35 0.96
UniRef50_Q16SX1 Cluster: Mitogen activated protein kinase kinase... 35 0.96
UniRef50_Q7NGY2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 35 1.3
UniRef50_Q5SJP9 Cluster: 5-carboxymethyl-2-hydroxymuconate semia... 35 1.3
UniRef50_A3ER29 Cluster: NAD-dependent aldehyde dehydrogenase; n... 35 1.3
UniRef50_A3BFM0 Cluster: Putative uncharacterized protein; n=2; ... 35 1.3
UniRef50_Q4J9S9 Cluster: Aldehyde dehydrogenase; n=1; Sulfolobus... 35 1.3
UniRef50_O32507 Cluster: Succinate-semialdehyde dehydrogenase [N... 35 1.3
UniRef50_Q89N88 Cluster: Methylmalonate-semialdehyde dehydrogena... 34 2.2
UniRef50_Q74E56 Cluster: Aldehyde dehydrogenase family protein; ... 34 2.2
UniRef50_Q5HLA7 Cluster: Aldehyde dehydrogenase family protein; ... 34 2.2
UniRef50_P25553 Cluster: Aldehyde dehydrogenase A; n=57; Bacteri... 34 2.2
UniRef50_Q0C0P8 Cluster: Succinylglutamic semialdehyde dehydroge... 33 2.9
UniRef50_Q22MH3 Cluster: Putative uncharacterized protein; n=1; ... 33 2.9
UniRef50_UPI0000ECD688 Cluster: Histone-lysine N-methyltransfera... 33 3.9
UniRef50_Q39H94 Cluster: Methylmalonate-semialdehyde dehydrogena... 33 3.9
UniRef50_Q6GVP0 Cluster: Possible polyketide synthase; n=15; Act... 33 3.9
UniRef50_A0LKD3 Cluster: Aldehyde dehydrogenase; n=1; Syntrophob... 33 3.9
UniRef50_Q97YT9 Cluster: Methylmalonate-semialdehyde dehydrogena... 33 3.9
UniRef50_Q99708 Cluster: Retinoblastoma-binding protein 8; n=27;... 33 5.1
UniRef50_UPI000050FFD5 Cluster: COG1012: NAD-dependent aldehyde ... 32 6.8
UniRef50_Q72KD3 Cluster: Aldehyde dehydrogenase; n=2; Thermus th... 32 6.8
UniRef50_Q6A9P5 Cluster: Putative immunogenic protein antigen 84... 32 6.8
UniRef50_A5KNY9 Cluster: Putative uncharacterized protein; n=1; ... 32 6.8
UniRef50_Q4Q7X4 Cluster: Dynein heavy chain, putative; n=10; Try... 32 6.8
UniRef50_A7HAX3 Cluster: Methylmalonate-semialdehyde dehydrogena... 32 8.9
UniRef50_A2F7J4 Cluster: Putative uncharacterized protein; n=1; ... 32 8.9
UniRef50_Q8NF91 Cluster: Nesprin-1; n=45; Eukaryota|Rep: Nesprin... 32 8.9
>UniRef50_Q9VNX4 Cluster: CG7145-PA, isoform A; n=4; Diptera|Rep:
CG7145-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 574
Score = 253 bits (619), Expect = 2e-66
Identities = 117/172 (68%), Positives = 140/172 (81%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
LK TAS ED+PIVI GK E RYQVMPHDH K+A +YYA +K IEKAI+ +V+ Q
Sbjct: 63 LKGTASSCEDIPIVIGGKEYKTPEVRYQVMPHDHQHKLASFYYADKKLIEKAIKTAVETQ 122
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFN 360
+WDR + +R+KIW+ AA+LMA YRQ LNAAT+LGQSK+ IQAEID+AAELIDF R N
Sbjct: 123 PKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSAAELIDFIRMN 182
Query: 361 VHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+FLKE +KYQPISE+ +TKNSLR+RGIDGFIAA+SPFNFTAIGGNL+YTP
Sbjct: 183 AYFLKEVTKYQPISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNLSYTP 234
>UniRef50_UPI00006A1A38 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor (EC 1.5.1.12)
(P5C dehydrogenase) (Aldehyde dehydrogenase 4A1).; n=3;
Xenopus tropicalis|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor (EC 1.5.1.12)
(P5C dehydrogenase) (Aldehyde dehydrogenase 4A1). -
Xenopus tropicalis
Length = 510
Score = 171 bits (416), Expect = 8e-42
Identities = 82/172 (47%), Positives = 117/172 (68%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
L + E++P V+ G+ + + RYQV P HS ++AKY YA ++ + KAI A++ +
Sbjct: 44 LHELKATTEEIPCVVGGEEVWTKDVRYQVSPFKHSHRVAKYCYADKELLNKAINAAMGVR 103
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFN 360
WD P+ +R +I+ AA+L++G R + A T++GQ K+ IQAEIDAAAELIDFFRFN
Sbjct: 104 KEWDLKPVQDRAQIFFKAADLLSGPRRAEILAKTMIGQGKTAIQAEIDAAAELIDFFRFN 163
Query: 361 VHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+ E + QPI S ++ NS+ +RG++GFIAA+SPFNFTAIGGNLA P
Sbjct: 164 AKYALELTHEQPI--SIPVSTNSMVYRGLEGFIAAVSPFNFTAIGGNLAGAP 213
>UniRef50_Q8T0Q8 Cluster: GH13449p; n=4; Sophophora|Rep: GH13449p -
Drosophila melanogaster (Fruit fly)
Length = 614
Score = 170 bits (414), Expect = 1e-41
Identities = 83/165 (50%), Positives = 113/165 (68%)
Frame = +1
Query: 22 IEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTP 201
+E VPIVI G+ E QV+P+D + IA Y +A I+ AI SV+AQ +WD+
Sbjct: 79 VEHVPIVINGQEFQAKEDFQQVLPYDIQQPIAHYGHAHRVLIQMAIDKSVEAQVKWDKVR 138
Query: 202 LTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKEN 381
L++R+ IW+ AA L+AG YR ++ AAT+LGQ K++ QAE+D AEL+DF R N FL+E
Sbjct: 139 LSDRIDIWERAAMLIAGRYRYNIIAATMLGQGKTLRQAEMD-VAELVDFMRINPVFLREL 197
Query: 382 SKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+ Y+PI + +NS+R RG+ GF+AAISPFNFT I NLAYTP
Sbjct: 198 ANYEPIRDIQNNCRNSMRLRGLSGFVAAISPFNFTGIAANLAYTP 242
>UniRef50_P30038 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor; n=34;
Eumetazoa|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 563
Score = 169 bits (411), Expect = 3e-41
Identities = 82/172 (47%), Positives = 116/172 (67%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
LK +E +P V+ + + + +YQV P +H K+AK+ YA + + KAI+A++ A+
Sbjct: 54 LKDLKGRMEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAAR 113
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFN 360
WD P+ +R +I+ AA++++G R + A T++GQ K+VIQAEIDAAAELIDFFRFN
Sbjct: 114 KEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFN 173
Query: 361 VHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+ E QPIS P + NS +RG++GF+AAISPFNFTAIGGNLA P
Sbjct: 174 AKYAVELEGQQPISVPP--STNSTVYRGLEGFVAAISPFNFTAIGGNLAGAP 223
>UniRef50_P0C2X9 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor; n=36;
Euteleostomi|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor - Rattus
norvegicus (Rat)
Length = 563
Score = 167 bits (407), Expect = 1e-40
Identities = 81/164 (49%), Positives = 113/164 (68%)
Frame = +1
Query: 25 EDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPL 204
E +P V+ + + + RYQ+ P +H K+AK+ YA + + KAI+A+V A+ WD P+
Sbjct: 61 EAIPCVVGDEEVWTSDVRYQLSPFNHGHKVAKFCYADKALLNKAIEAAVLARKEWDLKPV 120
Query: 205 TERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENS 384
+R +I+ AA++++G R + A T++GQ K+VIQAEIDAAAELIDFFRFN F E
Sbjct: 121 ADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELE 180
Query: 385 KYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
QPIS P + N + +RG++GF+AAISPFNFTAIGGNLA P
Sbjct: 181 GEQPISVPP--STNHVVYRGLEGFVAAISPFNFTAIGGNLAGAP 222
>UniRef50_Q5BVL1 Cluster: SJCHGC02702 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC02702 protein - Schistosoma
japonicum (Blood fluke)
Length = 224
Score = 162 bits (394), Expect = 4e-39
Identities = 82/162 (50%), Positives = 106/162 (65%)
Frame = +1
Query: 31 VPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTE 210
VPI I ++ PR QV P +HSK +A +YYASE+ I AIQ+ + A+ W RT E
Sbjct: 59 VPICIGSSELSSEHPRKQVWPFEHSKTLANFYYASEEQINSAIQSCLAARDSWSRTSFDE 118
Query: 211 RVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKY 390
R KI+ AA+L++ +R+ L A+TILGQ+K++ QAEIDAAAEL DF RFNV F E Y
Sbjct: 119 RAKIFLKAADLISNEHREELLASTILGQAKTIFQAEIDAAAELADFLRFNVQFASEALLY 178
Query: 391 QPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+PI+ I N + +R +GF AAI PFNFTAI GNL P
Sbjct: 179 RPINTKDAI--NKVVYRPNEGFWAAIPPFNFTAIAGNLVSAP 218
>UniRef50_Q9NKR5 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, putative; n=7; Eukaryota|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase, putative
- Leishmania major
Length = 560
Score = 148 bits (358), Expect = 9e-35
Identities = 73/171 (42%), Positives = 103/171 (60%)
Frame = +1
Query: 4 KRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQT 183
K + + PI+I GK T MP DH +IAK Y A+ + +KA++A+V+A
Sbjct: 41 KEARGEVRECPIMIGGKPYTSSNIIKATMPSDHQVQIAKAYNATPELAKKAVEAAVEASK 100
Query: 184 RWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNV 363
W + P +R I+ AA L++ YR + A T+LGQSK+ QAEID AE DF R+N+
Sbjct: 101 EWSQVPFRDRAAIFYKAAHLLSTKYRHEMRAVTMLGQSKNPWQAEIDCVAEACDFIRWNI 160
Query: 364 HFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
HF +E QP S S + N+ +R ++GF++AI+PFNFTAI NLA TP
Sbjct: 161 HFAEELYAQQPRSVSNSGVWNTTDYRPLEGFVSAITPFNFTAIAANLAGTP 211
>UniRef50_Q9P8I0 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor; n=8;
Dikarya|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor - Emericella
nidulans (Aspergillus nidulans)
Length = 572
Score = 138 bits (335), Expect = 5e-32
Identities = 69/162 (42%), Positives = 102/162 (62%)
Frame = +1
Query: 31 VPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTE 210
VP+VIAGK + Q P H +A Y A+ K ++ AI+++++A+ W TP +
Sbjct: 68 VPLVIAGKEVKSSSSLTQSNPASHGP-VATYSNATAKDVQAAIESALEARKSWASTPFAD 126
Query: 211 RVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKY 390
R ++ AA+L++ YR + A T+ GQ K+ QAEID+AAEL DFFRF V + ++
Sbjct: 127 RASVFLKAADLISTKYRYDVMALTMHGQGKNAWQAEIDSAAELCDFFRFGVKYAEDLYAQ 186
Query: 391 QPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
QP+ +P + N + +R ++GF+ AISPFNFTAIGGNLA P
Sbjct: 187 QPVHHAPGVW-NRVEYRPLEGFVYAISPFNFTAIGGNLAGAP 227
>UniRef50_A1DMS3 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase PrnC; n=11; Pezizomycotina|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase PrnC -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 578
Score = 134 bits (324), Expect = 1e-30
Identities = 69/163 (42%), Positives = 101/163 (61%)
Frame = +1
Query: 28 DVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLT 207
+VP+VIAGK I + Q P + +A Y A+ ++ AI A+++A+ W T
Sbjct: 74 NVPLVIAGKEIKSSQTFTQSNPASRAP-VATYSNATASDVQAAIDAALEARKSWAATSFA 132
Query: 208 ERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSK 387
+R ++ AA+L++ YR + A T+ GQ K+ QAEIDAAAEL DFFRF V + ++
Sbjct: 133 DRASVFLKAADLISTKYRYDIMALTMHGQGKNAWQAEIDAAAELCDFFRFGVKYAEDMYA 192
Query: 388 YQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
QP+ +P + N + +R ++GF+ AISPFNFTAIGGNLA P
Sbjct: 193 QQPVHHAPGVW-NRVEYRPLEGFVYAISPFNFTAIGGNLAGAP 234
>UniRef50_Q0BZR5 Cluster: 1-pyrroline-5-carboxylate dehydrogenase;
n=1; Hyphomonas neptunium ATCC 15444|Rep:
1-pyrroline-5-carboxylate dehydrogenase - Hyphomonas
neptunium (strain ATCC 15444)
Length = 536
Score = 133 bits (321), Expect = 3e-30
Identities = 71/159 (44%), Positives = 93/159 (58%)
Frame = +1
Query: 40 VIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVK 219
VI GK + G PH H+ + Y A + AI A++DA+ W R R
Sbjct: 39 VINGKKVDTGTSTDMREPHAHANSLGTYASAGAPEAQAAITAAIDARHDWSRMDTAARRA 98
Query: 220 IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPI 399
++ AAEL+AG + L AAT+L QSK+ Q+EIDA+ ELIDF RFNV F ++ QP+
Sbjct: 99 VFLRAAELLAGPFNDRLLAATMLAQSKTAFQSEIDASCELIDFLRFNVAFAEQIEAMQPL 158
Query: 400 SESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
S SP +N L R +DGF+ A +PFNFTAI GNLA P
Sbjct: 159 S-SPA-ERNRLEHRPLDGFVFAAAPFNFTAIAGNLAIAP 195
>UniRef50_Q8CJR1 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase; n=43; cellular organisms|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase -
Streptomyces coelicolor
Length = 546
Score = 128 bits (308), Expect = 1e-28
Identities = 68/173 (39%), Positives = 102/173 (58%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVM-PHDHSKKIAKYYYASEKTIEKAIQASVDA 177
LK A D+P I G+ G R+ V+ PH+H ++ Y A++ + AI A++ A
Sbjct: 32 LKELADNPIDLPCTIGGEKRMGGGERFDVVQPHNHKSRLGTYANATQADAQDAIDAALAA 91
Query: 178 QTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRF 357
W +R I AAEL++G +R+++ A+T+LGQSK+ QAEID+ ELIDF+RF
Sbjct: 92 APAWRAMSFDDRAAIILRAAELLSGPWRETIAASTMLGQSKTAQQAEIDSPCELIDFWRF 151
Query: 358 NVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
NVH+ + QP + S + N + R ++GF+ AI+PFNF+AI NL P
Sbjct: 152 NVHYARNILAEQPPANSQGVW-NRMDHRPLEGFVYAITPFNFSAIAANLPTAP 203
>UniRef50_P07275 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor; n=20;
Dikarya|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 575
Score = 126 bits (303), Expect = 4e-28
Identities = 68/166 (40%), Positives = 98/166 (59%), Gaps = 3/166 (1%)
Frame = +1
Query: 28 DVPIVIAGKNITEGEPRY---QVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRT 198
+VP+VI G+ I + R Q P +H + +A A+EK + A++A+ DA+ W
Sbjct: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119
Query: 199 PLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKE 378
P +R I+ AA+L++ YR + AAT+LGQ K+V QAEID EL DFFR+ V + +
Sbjct: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179
Query: 379 NSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
QP+ ES T N +R ++GF+ A+SPFNFTAI NL P
Sbjct: 180 LYAQQPV-ESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAP 224
>UniRef50_A1WRX5 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase; n=1; Verminephrobacter eiseniae
EF01-2|Rep: Delta-1-pyrroline-5-carboxylate
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 532
Score = 124 bits (300), Expect = 9e-28
Identities = 62/165 (37%), Positives = 98/165 (59%)
Frame = +1
Query: 22 IEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTP 201
+ ++P V+ GK I + PHD S+ +A+ + S+ ++ AI+++++A W R
Sbjct: 37 VVEIPAVVGGKKIFSDDVEIIHAPHDRSRVLARVHRPSQAQVDDAIRSNLEAAHDWSRMD 96
Query: 202 LTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKEN 381
+R I AA ++ G R +NAAT+LGQSK++ +AE D+A ELIDF FN ++
Sbjct: 97 FADRAAIMHRAAGIVRGRLRHRINAATMLGQSKTLDEAEADSACELIDFLHFNTFNAQQI 156
Query: 382 SKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
QP+S +N +R ++GF+ A+SPFNFTAIG NL+ P
Sbjct: 157 VTDQPLSVQD--AQNRCDWRPLEGFVYAVSPFNFTAIGTNLSCAP 199
>UniRef50_Q2PIP5 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase; n=2; Trichocomaceae|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase -
Aspergillus oryzae
Length = 534
Score = 113 bits (273), Expect = 2e-24
Identities = 63/175 (36%), Positives = 103/175 (58%), Gaps = 3/175 (1%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHD-HSKKIAKYYYASEKTIE-KAIQASVD 174
L S + ++P +I GK I G QV P D + +A+Y+ +TI+ KAI +++
Sbjct: 31 LAEMESTVTEIPSIINGKRIRTGHKGKQVNPWDRYGAPLAEYHQVDPETIKAKAIPGALE 90
Query: 175 AQTRWDRTPLTERVKIWQTAAELMAGA-YRQSLNAATILGQSKSVIQAEIDAAAELIDFF 351
A+ W +R I++ AA+L+ Y+ L AA+++GQ K+ QAE D AE+ID
Sbjct: 91 ARKHWANMSFKDRCAIYKKAAKLVESPKYQWKLMAASMIGQGKTCGQAEGDCIAEVIDTL 150
Query: 352 RFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
F+V+F + QP + + + + L +R ++GF+ AISPFNFTA+G ++A+TP
Sbjct: 151 NFHVYFCAQLYDQQPPKQLDS-SSSRLDYRPLEGFVLAISPFNFTALGAHIAFTP 204
>UniRef50_Q5B0A8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 610
Score = 112 bits (270), Expect = 4e-24
Identities = 56/121 (46%), Positives = 80/121 (66%)
Frame = +1
Query: 154 AIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAA 333
AI++++ A+ W+ TP +R I+ AAEL+ G YR L AAT+LGQ K++ QAEIDAAA
Sbjct: 193 AIESALKAKKDWENTPFIDRAAIFLKAAELVTGKYRYELIAATMLGQGKNIWQAEIDAAA 252
Query: 334 ELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYT 513
EL DFFR N +F E + QP + + + +R ++GF+ A+SPFN TA+GG+L
Sbjct: 253 ELADFFRLNCNFAAELLERQP-TRGTVGMWSRMEYRPLEGFVYAVSPFNLTALGGSLLSG 311
Query: 514 P 516
P
Sbjct: 312 P 312
>UniRef50_Q2J962 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase; n=23; cellular organisms|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 588
Score = 111 bits (266), Expect = 1e-23
Identities = 64/150 (42%), Positives = 83/150 (55%)
Frame = +1
Query: 67 GEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM 246
G R V PH + + + ++ A+ A+ A W R + AAE +
Sbjct: 64 GPARDVVQPHAYRRVLGTLRESTHADAAAAVAAAKKAAPGWRDLGFAGRAAVLLRAAEAL 123
Query: 247 AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKN 426
AG +R +LNAAT+LGQSK+ QAEIDAA ELIDF+RFNV F E + S N
Sbjct: 124 AGPWRDTLNAATMLGQSKTCQQAEIDAACELIDFWRFNVMFAAE--LLADVPASGIGEWN 181
Query: 427 SLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
L R ++GF+ A+SPFNFTAI GNLA P
Sbjct: 182 RLDLRPLEGFVYAVSPFNFTAIAGNLATAP 211
>UniRef50_Q4T8X0 Cluster: Chromosome undetermined SCAF7712, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF7712, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 774
Score = 97.9 bits (233), Expect = 1e-19
Identities = 60/173 (34%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
L R E++P V+ +++ + RYQ+ P +HS K+AK+ YA ++ I KAI ASV A+
Sbjct: 33 LDRVKRSTEEIPCVVGDQHVWTRDVRYQLSPFNHSHKVAKFCYADKELINKAILASVAAR 92
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFN 360
WD P+ +R ++ AA++++G R + A T++GQ V + D++ R
Sbjct: 93 REWDLKPVQDRAQVLFKAADVISGPRRAEILAKTMIGQ---VEPPQPDSSRWTA---RAA 146
Query: 361 VHFLKENSKYQPISESPTITKNSLRF-RGIDGFIAAISPFNFTAIGGNLAYTP 516
+ ++ + S RF GF+AA++PFNFTAIGGNLA TP
Sbjct: 147 PTPCSTGAWRSEVTRPAPPPRCSSRFCPPPQGFVAAVAPFNFTAIGGNLAGTP 199
>UniRef50_UPI0000E4A52D Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 492
Score = 91.1 bits (216), Expect = 1e-17
Identities = 44/103 (42%), Positives = 60/103 (58%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
LKR ED+P VI GK I G +V P DH + K +YA + IE AI+ +++A+
Sbjct: 58 LKRRWGTQEDIPCVIGGKEIFTGNTETEVAPFDHQHVLCKVHYADKMVIETAIKTALEAR 117
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVI 309
WDR PL ERV I AA+L G YR L A+ ++GQ +V+
Sbjct: 118 DEWDRRPLQERVAILVKAADLACGKYRAELAASCMMGQGNAVV 160
>UniRef50_Q95TY8 Cluster: GH20963p; n=1; Drosophila
melanogaster|Rep: GH20963p - Drosophila melanogaster
(Fruit fly)
Length = 581
Score = 76.2 bits (179), Expect = 4e-13
Identities = 46/163 (28%), Positives = 78/163 (47%)
Frame = +1
Query: 28 DVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLT 207
+VP +I + + + PH +A YYA+ K IE AI++++ AQ W P+
Sbjct: 84 EVPTIIGDDTVYTMDTQRVCCPHHLQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIA 143
Query: 208 ERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSK 387
+R+ IW+ AA ++ L ++ SK+ A D L+ R N +L+ S+
Sbjct: 144 QRLAIWRRAATIIE-EDELRLRVFLMMTLSKTADDATRD-IRRLLTSLRANADYLEHLSE 201
Query: 388 YQPISESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+ + S R +DGF+AA++PF A+ +LA P
Sbjct: 202 LRFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSSLALCP 244
>UniRef50_Q4JC93 Cluster: Aldehyde dehydrogenase; n=2;
Sulfolobaceae|Rep: Aldehyde dehydrogenase - Sulfolobus
acidocaldarius
Length = 521
Score = 58.4 bits (135), Expect = 9e-08
Identities = 47/163 (28%), Positives = 83/163 (50%), Gaps = 5/163 (3%)
Frame = +1
Query: 10 TASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRW 189
++ + ++ P++I + I E + + ++ + A+E + +AI+ + +A W
Sbjct: 33 SSGIGKEYPLIIGKREIRTNEKIIVTVSFNSDLRLGIFQKATENELNEAIETAENAYKEW 92
Query: 190 DRTPLTERVKIWQTAAELMAGAYRQSLNAATIL---GQSKSVIQAEIDAAAELIDFFRFN 360
+ +RV+I AAELMA ++ +L AATI G+++ AE+D E ID+ R+
Sbjct: 93 QYSDWKDRVEIAMRAAELMA-RHKFAL-AATITFENGKNRYEAMAEVD---ETIDYLRYY 147
Query: 361 VHFLKENSKYQPISESPTITKNSLRFRGID--GFIAAISPFNF 483
+ L+EN Y ES I KN + + G +SPFNF
Sbjct: 148 AYLLEENRGYIREMES-RIYKNEKGYSVMRPYGTWFVVSPFNF 189
>UniRef50_Q83DR6 Cluster: Proline
dehydrogenase/delta-1-pyrroline-5-carboxylate
dehydrogenase; n=7; Proteobacteria|Rep: Proline
dehydrogenase/delta-1-pyrroline-5-carboxylate
dehydrogenase - Coxiella burnetii
Length = 1046
Score = 54.4 bits (125), Expect = 1e-06
Identities = 40/144 (27%), Positives = 69/144 (47%)
Frame = +1
Query: 52 KNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQT 231
+ I G+P + P D+ ++I A+E +EKAIQA A WD+ ++ R I +
Sbjct: 564 QEIKNGKPVFD--PTDNRRQIGVIELANESDVEKAIQAGHSAFPNWDQKGISARATILRK 621
Query: 232 AAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESP 411
A+L+ ++ L A ++ + +Q + E DF R+ +++ + +
Sbjct: 622 MADLLE-KHKAEL-MAVVVREGGRTLQNALSEVREATDFCRYYAEQAEQHLSDKAL-PGY 678
Query: 412 TITKNSLRFRGIDGFIAAISPFNF 483
T N+LR G G I ISP+NF
Sbjct: 679 TGESNTLRMNG-RGIILCISPWNF 701
>UniRef50_Q082D7 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|Rep:
Aldehyde dehydrogenase - Shewanella frigidimarina
(strain NCIMB 400)
Length = 460
Score = 50.0 bits (114), Expect = 3e-05
Identities = 37/119 (31%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Frame = +1
Query: 130 ASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATI-LGQSKSV 306
AS+ +++AI+ + DA W T TER +I AAEL+ N TI +G+ S
Sbjct: 20 ASDSEVKQAIENAHDAFLLWKNTGFTERARIMHAAAELLRRDVDYYANLLTIEMGKLISE 79
Query: 307 IQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+AEI +A++ D++ N L K I L G + AI P+NF
Sbjct: 80 AKAEIALSADIFDYYADNAQKLLAPQKLPVADADAEILCEPL------GVLLAIEPWNF 132
>UniRef50_Q703Z2 Cluster: Aldehyde dehydrogenase; n=1; Thermoproteus
tenax|Rep: Aldehyde dehydrogenase - Thermoproteus tenax
Length = 528
Score = 48.8 bits (111), Expect = 7e-05
Identities = 42/150 (28%), Positives = 61/150 (40%)
Frame = +1
Query: 34 PIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTER 213
PI I GK + + P D S KI + + + + A+ +V+A W R ER
Sbjct: 42 PIYIGGKEVYTSGKFEKRSPFDTSIKIGTFQRGTPEEFKAALSKAVEAFPEWSRLDWRER 101
Query: 214 VKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQ 393
+I A+L+ R L AA K+ +A + E ID R+ V + + Y
Sbjct: 102 ARILAKLADLIE-RDRFKLAAAITYEVGKNRFEA-LAEIHEAIDVLRYYVELIHKMDGYV 159
Query: 394 PISESPTITKNSLRFRGIDGFIAAISPFNF 483
SP + L G ISPFNF
Sbjct: 160 LQMRSPIPNERPLSVLRPYGAWFVISPFNF 189
>UniRef50_UPI00015BD0F0 Cluster: UPI00015BD0F0 related cluster; n=1;
unknown|Rep: UPI00015BD0F0 UniRef100 entry - unknown
Length = 477
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/150 (24%), Positives = 68/150 (45%), Gaps = 2/150 (1%)
Frame = +1
Query: 40 VIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVK 219
++ G+ I G + P+D++K I K Y ++ +EKAI+ + + E+ +
Sbjct: 7 ILGGEFIKTGTVLDVIYPYDNTK-IGKSYVVNDSYVEKAIEKAKIGLKKLSSLSAFEKYE 65
Query: 220 IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKE-NSKYQP 396
I +EL+ ++ + + K++ +A ++ I+ FRF+ K K P
Sbjct: 66 ILYKTSELLR-KNKEEIARTIVYEVGKTIKEARVEVD-RAIETFRFSAEEAKRIYGKTYP 123
Query: 397 ISESPT-ITKNSLRFRGIDGFIAAISPFNF 483
+ P +K R G + AISPFNF
Sbjct: 124 VDAHPNGKSKFGFYIRVPAGIVVAISPFNF 153
>UniRef50_Q9HKJ5 Cluster: Aldehyde dehydrogenase related protein;
n=3; Thermoplasmatales|Rep: Aldehyde dehydrogenase
related protein - Thermoplasma acidophilum
Length = 515
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Frame = +1
Query: 43 IAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKI 222
I ++I E + + P D S+ IA + AS++++ KA+ + W +R
Sbjct: 43 IIKEDIVESKKIKDISPIDGSE-IATFQLASDESVNKAVDMLYRSYKNWYNIGYMKRALT 101
Query: 223 WQTAAELMAGAYRQSLNAATILGQSKSVIQAE-IDAAAELIDFFRFNVHFLKENSKYQPI 399
+ AA +++ Q A IL + E I E IDF R+ L EN + +
Sbjct: 102 FLKAAGMLSD---QKFKFAAILTYENGKNRYEAIGDVDEAIDFMRYYAINLIENQGFIKL 158
Query: 400 SESPTITKNSLRFRGIDGFIAAISPFNFTAIGGNLAYTP 516
+ + S+ G ISPFNF +IG ++ P
Sbjct: 159 TGKAYKNEESMSVMKPYGVFGVISPFNFFSIGVGMSSGP 197
>UniRef50_A4Z2X8 Cluster: Bifunctional putA protein: proline
dehydrogenase (N-terminal); delta-
1-pyrroline-5-carboxylate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Bifunctional putA protein:
proline dehydrogenase (N-terminal); delta-
1-pyrroline-5-carboxylate dehydrogenase - Bradyrhizobium
sp. (strain ORS278)
Length = 1031
Score = 46.0 bits (104), Expect = 5e-04
Identities = 37/139 (26%), Positives = 57/139 (41%)
Frame = +1
Query: 67 GEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM 246
G PR P D A E+AI A+V T W T +R K+ + AA+++
Sbjct: 554 GMPRRLTSPFDPGVVAGSVIEADAAVAERAIAAAVVGLTSWRMTSAAQRAKVLRRAADMI 613
Query: 247 AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKN 426
+ ++ + ++ I I E +DF R+ + + PT N
Sbjct: 614 EQRRARLIHLLAV--EAGKTIDDAIAEIREAVDFCRYYAAEGERLFGAELGLPGPTGESN 671
Query: 427 SLRFRGIDGFIAAISPFNF 483
+LR R G AISP+NF
Sbjct: 672 ALRLRP-RGVFVAISPWNF 689
>UniRef50_Q97D25 Cluster: NADP-dependent glyceraldehyde-3-phosphate
dehydrogenase; n=27; Firmicutes|Rep: NADP-dependent
glyceraldehyde-3-phosphate dehydrogenase - Clostridium
acetobutylicum
Length = 482
Score = 44.8 bits (101), Expect = 0.001
Identities = 42/136 (30%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Frame = +1
Query: 91 PHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM--AGAYRQ 264
P+D S I K S++ +++ ++S AQ +W TP+ ER +I + AA+++ Y
Sbjct: 33 PYDGSL-IGKVQALSKEEVDEIFKSSRTAQKKWGETPINERARIMRKAADILDDNAEYIA 91
Query: 265 SLNAATILGQSKSVIQAEIDAAAELIDF-FRFNVHFLKE--NSKYQPISESPTITKNSLR 435
+ + I KS + +E+ A+ I F H E NS P S+ K SL
Sbjct: 92 KILSNEIAKDLKSSL-SEVKRTADFIRFTANEGTHMEGEAINSDNFPGSKK---DKLSLV 147
Query: 436 FRGIDGFIAAISPFNF 483
R G + AISPFN+
Sbjct: 148 ERVPLGIVLAISPFNY 163
>UniRef50_Q1AXK7 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Aldehyde dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 486
Score = 44.0 bits (99), Expect = 0.002
Identities = 36/142 (25%), Positives = 60/142 (42%)
Frame = +1
Query: 67 GEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM 246
GE +V+ +++A+ AS + I +A +A+ +AQ RW ER ++ A+L+
Sbjct: 20 GERAREVVSPVTGERLAEAPEASAEEISRAARAAREAQPRWAALSAWERAEVCHAVADLL 79
Query: 247 AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKN 426
++ L L Q K I E + FR +K + S K
Sbjct: 80 EER-KEELARQLSLEQGKPYRSEAIPDIEETAENFRVAAEDVKRLET--AVIPSQDANKR 136
Query: 427 SLRFRGIDGFIAAISPFNFTAI 492
FR +G A I+P+NF +
Sbjct: 137 IFTFREPNGVYACITPWNFPTV 158
>UniRef50_O24897 Cluster: Delta-1-pyrroline-5-carboxylate
dehydrogenase; n=18; Campylobacterales|Rep:
Delta-1-pyrroline-5-carboxylate dehydrogenase -
Helicobacter pylori (Campylobacter pylori)
Length = 1185
Score = 42.7 bits (96), Expect = 0.005
Identities = 25/106 (23%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = +1
Query: 82 QVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYR 261
+V H KKIA + A ++ I KA++ + ++R+ + TE + A+L
Sbjct: 525 EVFDRIHHKKIASVHLADKEAILKALEVAKSDKSRFSQKSFTEIHALMSQTAQLFRERRG 584
Query: 262 QSLNAATI-LGQSKSVIQAEIDAAAELIDFFRFNVHFLKE-NSKYQ 393
+ + + +G++ + AE+ A + ++F+ +++ L+E N+K Q
Sbjct: 585 DLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNTKTQ 630
>UniRef50_A3WI91 Cluster: Succinate-semialdehyde dehydrogenase
(NAD(P)+); n=1; Erythrobacter sp. NAP1|Rep:
Succinate-semialdehyde dehydrogenase (NAD(P)+) -
Erythrobacter sp. NAP1
Length = 483
Score = 42.3 bits (95), Expect = 0.006
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Frame = +1
Query: 31 VPIVIAGKNITEG-EPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLT 207
V ++IAG + EG + ++ + ++I AS+ ++ A+ A+ W TP
Sbjct: 7 VKMLIAGNWVAEGGDGEMPIVNPANEERIGSAPKASKAQLDAALAAADAGFQLWSNTPAI 66
Query: 208 ERVKIWQTAAELMAGAYRQSLNAATI-LGQSKSVIQAEIDAAAELIDF 348
ER ++ + AAEL+ T+ +G+ + E AA+LIDF
Sbjct: 67 ERFRVIRRAAELLRERAEGIARVMTLEMGKPHAQALGETTGAADLIDF 114
>UniRef50_Q9K9B2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase 1;
n=57; Bacteria|Rep: 1-pyrroline-5-carboxylate
dehydrogenase 1 - Bacillus halodurans
Length = 515
Score = 42.3 bits (95), Expect = 0.006
Identities = 37/153 (24%), Positives = 66/153 (43%)
Frame = +1
Query: 25 EDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPL 204
++ P++I G+ +T + P + + A++ EKAIQ++ +A W
Sbjct: 35 KEYPLIINGERVTTEDKIQSWNPARKDQLVGSVSKANQDLAEKAIQSADEAFQTWRNVNP 94
Query: 205 TERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENS 384
ER I AA ++ + +A + K +A+ D AE IDF + + E +
Sbjct: 95 EERANILVKAAAIIR-RRKHEFSAWLVHEAGKPWKEADAD-TAEAIDFLEYYARQMIELN 152
Query: 385 KYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+ + I P + + F G ISP+NF
Sbjct: 153 RGKEILSRP--GEQNRYFYTPMGVTVTISPWNF 183
>UniRef50_Q21J80 Cluster: Aldehyde dehydrogenase; n=1;
Saccharophagus degradans 2-40|Rep: Aldehyde
dehydrogenase - Saccharophagus degradans (strain 2-40 /
ATCC 43961 / DSM 17024)
Length = 462
Score = 41.9 bits (94), Expect = 0.008
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Frame = +1
Query: 106 KKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATI 285
+++ Y ++ +I++ + + A +W +T L ER+ + + A +A + TI
Sbjct: 22 QEVGSYALLAKNSIDRKLDQADVAFKQWRKTALDERIALIKRVATQLAENKQGLATFITI 81
Query: 286 -LGQSKSVIQAEIDAAAELIDFFRFNVH-FLKENSKYQPISESPTITKNSLRFRGIDGFI 459
+G+ + +AEID L D++ N H FL+ +PIS + + + + F+ + G I
Sbjct: 82 EMGKPINQAKAEIDKCIALCDYYCKNAHQFLRA----KPISSN--LKNSRVEFQPL-GVI 134
Query: 460 AAISPFNF 483
+ P+NF
Sbjct: 135 LGVMPWNF 142
>UniRef50_Q0S1Y5 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcus
sp. RHA1|Rep: Aldehyde dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 489
Score = 41.9 bits (94), Expect = 0.008
Identities = 34/157 (21%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Frame = +1
Query: 16 SVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDR 195
S+ + + +AG+ T + +V P D + Y A+ +E A A+ AQ W
Sbjct: 12 SIADGRTLYVAGRWSTTTDTFERVDPSDLRRVTGIYTSATPGNVESAYAAAGRAQPAWSE 71
Query: 196 TPLTERVKIWQTAAELM-AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFL 372
T ER ++AA+L+ + + +L +G++ +AE+ + ++ ++ + L
Sbjct: 72 TTAIERSDFLRSAADLLESRVHDAALTITADMGKAIRDARAEVLRSVAILRYYAGEI--L 129
Query: 373 KENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+ + + P ++ T+ G+ + AI+P+NF
Sbjct: 130 QPSGETYPSADPHTMLMTVEEPLGV---VCAITPWNF 163
>UniRef50_A3WGW3 Cluster: PutA; n=17; Proteobacteria|Rep: PutA -
Erythrobacter sp. NAP1
Length = 1076
Score = 40.3 bits (90), Expect = 0.025
Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 1/140 (0%)
Frame = +1
Query: 67 GEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM 246
GE MPHD ++ A+++ ++ A + Q WD +R + + AA+L
Sbjct: 598 GEIAPITMPHDLEAEVGTRRDATQEEVDAAFTRAAAIQPGWDALGGHKRALLLEEAADLF 657
Query: 247 AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPIS-ESPTITK 423
+ L+ ++ + I E +DF R+ + PI PT
Sbjct: 658 EAHTGEFLSLCQ--REAGKTLLDGIAEVREAVDFLRYYASEARRQFG-DPIQLPGPTGED 714
Query: 424 NSLRFRGIDGFIAAISPFNF 483
N+LR G G ISP+NF
Sbjct: 715 NTLRMHG-RGVFVTISPWNF 733
>UniRef50_Q8XHP4 Cluster: NADP-dependent glyceraldehyde-3-phosphate
dehydrogenas; n=20; Firmicutes|Rep: NADP-dependent
glyceraldehyde-3-phosphate dehydrogenas - Clostridium
perfringens
Length = 482
Score = 39.9 bits (89), Expect = 0.034
Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Frame = +1
Query: 133 SEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQ 312
S++ ++K I + AQ W+ PL ER + A+L+ +++ L I +K
Sbjct: 43 SKEDVDKIIDNAEKAQKSWNEVPLNERAHVLYKTADLLE-EHKEELANIMIREVAKDKKS 101
Query: 313 AEIDAAAELIDFFRFNVHFLKE-NSKYQPISESPTITKNSLRF--RGIDGFIAAISPFNF 483
A + + D+ RF K + + P P ++ + R G + AISPFN+
Sbjct: 102 A-LSEVSRTADYIRFTADAAKSMDGESIPSDNFPGFNRSKISVVTREPLGVVLAISPFNY 160
>UniRef50_Q62BD6 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=309; cellular organisms|Rep:
Methylmalonate-semialdehyde dehydrogenase - Burkholderia
mallei (Pseudomonas mallei)
Length = 552
Score = 39.9 bits (89), Expect = 0.034
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 3/164 (1%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
+K ++V + +I GK + GE V + A ++E AI A+ A
Sbjct: 48 MKHDSNVTPPLGHLIDGKRVDGGERVQPVFDPATGASTKRVRMADRPSVEAAIAAAQAAY 107
Query: 181 TRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQA--EIDAAAELIDFFR 354
W TP +R ++ L+ + L A K + A E+ E +++
Sbjct: 108 PAWRNTPPLKRARVMSRFKTLLE-EHANELCALITAEHGKVLADAMGELQRGIENVEYAS 166
Query: 355 FNVHFLK-ENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+ LK E+SK + P I S F+ + G +A I+PFNF
Sbjct: 167 YAPELLKGEHSK----NVGPAIDSWS-EFQAL-GVVAGITPFNF 204
>UniRef50_Q39NZ7 Cluster: Succinic semialdehyde dehydrogenase; n=13;
cellular organisms|Rep: Succinic semialdehyde
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 502
Score = 39.5 bits (88), Expect = 0.045
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Frame = +1
Query: 145 IEKAIQASVDAQTRWDRTPLTERVKIWQTAAEL-MAGAYRQSLNAATILGQSKSVIQAEI 321
+E+AI++S AQ W + ER K+ + +L +A A +L + G+ + + EI
Sbjct: 70 VEQAIESSALAQQGWQKRTSHERAKLLRAWFDLILANADDLALIMTSEQGKPLAEARGEI 129
Query: 322 DAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTA 489
AA +++F + Y + P K L R G AAI+P+NF A
Sbjct: 130 TYAASFVEWFAEEAKRV-----YGDVMPHPQGDKRILVIRQPIGVCAAITPWNFPA 180
>UniRef50_A5WEU6 Cluster: Aldehyde dehydrogenase; n=13;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Psychrobacter sp. PRwf-1
Length = 484
Score = 39.5 bits (88), Expect = 0.045
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +1
Query: 85 VMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAA-ELMAGAYR 261
+ P D S+ I +Y A E +E+AI A+ AQ W R P+ + I Q+ EL+A
Sbjct: 26 INPSDISETIGEYAQADESHVEEAIAAARRAQPEWARVPMERKQAILQSIGDELIARCDE 85
Query: 262 QSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFR 441
+ G+ + + EI + + +F V L++ S P + K +
Sbjct: 86 LGRLLSREEGKPFAEGRGEIYRSGQFFHYFAAEV--LRQMGDLAD-SVRPGV-KIEVTRE 141
Query: 442 GIDGFIAAISPFNF 483
+ G +A ISP+NF
Sbjct: 142 AV-GVVAIISPWNF 154
>UniRef50_A3V8Q9 Cluster: Succinate-semialdehyde dehydrogenase; n=3;
Alphaproteobacteria|Rep: Succinate-semialdehyde
dehydrogenase - Loktanella vestfoldensis SKA53
Length = 479
Score = 39.5 bits (88), Expect = 0.045
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Frame = +1
Query: 154 AIQASVDAQTRWDRTPLTERVKIWQTAAELMA-GAYRQSLNAATILGQSKSVIQAEIDAA 330
AIQA+ A W + P+ ER +I + A+ M A LG+ AEI +
Sbjct: 43 AIQAAARAFESWKKVPMVERARIQKACAQAMRDNAETVGAILNKELGRPLHACVAEISRS 102
Query: 331 AELIDFF-RFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
A+L+D + + S E +T++ L G + AI+PFN+
Sbjct: 103 ADLLDVYAEEGLRLTATMSLASGAGEKTIVTRDPL------GVVVAITPFNY 148
>UniRef50_Q8Y8I9 Cluster: Lmo0913 protein; n=11; Listeria|Rep:
Lmo0913 protein - Listeria monocytogenes
Length = 488
Score = 39.1 bits (87), Expect = 0.059
Identities = 43/163 (26%), Positives = 74/163 (45%), Gaps = 2/163 (1%)
Frame = +1
Query: 1 LKRTASVIEDVPIVIAGKNITEGEPRY--QVMPHDHSKKIAKYYYASEKTIEKAIQASVD 174
+K TA + I GK T+G+ + ++ + IAK A +KAI+A+ D
Sbjct: 3 IKETALPKVQTKLFINGK-WTDGDNKETKDIVNPANGDVIAKIAQAGPSETKKAIKAAKD 61
Query: 175 AQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFR 354
A W + L +RVK+ A+LM +L L Q K + +++ + ++ FR
Sbjct: 62 AFPDWAKMELADRVKLLHKIADLME-EKADTLAKIMTLEQGKPLKESKGEVLTG-VENFR 119
Query: 355 FNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
F + Y +P ++ + I G +AAI+P+NF
Sbjct: 120 FAAE--EARRLYGETIPAPNNHAFIVKKQPI-GVVAAITPWNF 159
>UniRef50_Q9Z672 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Zymomonas mobilis|Rep: Succinic semialdehyde
dehydrogenase - Zymomonas mobilis
Length = 458
Score = 38.7 bits (86), Expect = 0.078
Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 3/127 (2%)
Frame = +1
Query: 112 IAKYYYASEKTIEKAI-QASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATI- 285
+ KY S+K ++ ++ +A+ + W + + ER K+ AAE+ + TI
Sbjct: 14 VKKYPDFSDKQVKDSVDRAATVFKNDWSQRTIAERSKVLHKAAEIFRSDVDKYAKLLTID 73
Query: 286 LGQSKSVIQAEIDAAAELIDFFRFN-VHFLKENSKYQPISESPTITKNSLRFRGIDGFIA 462
+G+ + + E++ +A+++D++ N FL Q + E P + G +
Sbjct: 74 MGKKIAEARGEVNLSADILDYYAKNGEKFLAP----QKVEEKPGAVVKAFPL----GLLL 125
Query: 463 AISPFNF 483
AI P+NF
Sbjct: 126 AIEPWNF 132
>UniRef50_Q7Z1Q3 Cluster: Aldehyde dehydrogenase protein 12, isoform
a; n=3; Caenorhabditis|Rep: Aldehyde dehydrogenase
protein 12, isoform a - Caenorhabditis elegans
Length = 499
Score = 38.7 bits (86), Expect = 0.078
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Frame = +1
Query: 49 GKNIT-EGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIW 225
GK T E + V+ + +AK A+ +++ ++A+ DAQ+ W T +R K+
Sbjct: 18 GKRTTIESTETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADAQSAWGETTALDRGKVL 77
Query: 226 QTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAA--AELIDFF 351
A+L+ + + + + K + +A D A A+ DFF
Sbjct: 78 HKVADLIR-EHAEEIAIWEVKTNGKPIYEARCDIASSADTFDFF 120
>UniRef50_Q7WBK1 Cluster: Probable aldehyde dehydrogenase; n=2;
Bordetella|Rep: Probable aldehyde dehydrogenase -
Bordetella parapertussis
Length = 475
Score = 38.3 bits (85), Expect = 0.10
Identities = 35/150 (23%), Positives = 60/150 (40%)
Frame = +1
Query: 43 IAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKI 222
+AG+ GEP P D ++ Y +A + + +A++A+ +A W R ++
Sbjct: 9 VAGQWQDGGEPVALYNPSDLQEEAGVYMHAPVEMVNQAVRAAEEALDAWRGLHAMARSRL 68
Query: 223 WQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPIS 402
A+ + G R L A Q K + A + A D FR+ Y S
Sbjct: 69 LDGIADGLVGR-RDELAMAIAREQGKPLRDA-LAEATRAADIFRYFASETIRQKGYTYAS 126
Query: 403 ESPTITKNSLRFRGIDGFIAAISPFNFTAI 492
P + R G +A ++P+NF +
Sbjct: 127 IRPGVRVEVQ--RNPVGVVALVTPWNFPVV 154
>UniRef50_Q8U2S5 Cluster: Non-phosphorylating
glyceraldehyde-3-phosphate dehydrogenase; n=2;
Thermococcaceae|Rep: Non-phosphorylating
glyceraldehyde-3-phosphate dehydrogenase - Pyrococcus
furiosus
Length = 506
Score = 38.3 bits (85), Expect = 0.10
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 3/150 (2%)
Frame = +1
Query: 43 IAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRT-PLTERVK 219
IAGK I GE + + + IA+ S + IE+AI + + R P +R+
Sbjct: 28 IAGKWIY-GEKFKDIKSPINGEVIARVSILSREQIEEAISTTYEIGREKIRDYPGEKRIS 86
Query: 220 IWQTAAELMAGAYRQSLNAATI-LGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQP 396
+ AAE+M A+ + + G+ KS E+ A E ++ F F + Y P
Sbjct: 87 SFLKAAEMMKEAFDDFVRILILDAGKPKSNAMGEVKATIERLEKTTFE--FGRLIGDYIP 144
Query: 397 ISESP-TITKNSLRFRGIDGFIAAISPFNF 483
S T+ ++ R G I AISPFN+
Sbjct: 145 GDWSEETLESEAIVKREPYGLILAISPFNY 174
>UniRef50_A6GKH6 Cluster: Succinate-semialdehyde dehydrogenase
(NAD(P)+); n=1; Plesiocystis pacifica SIR-1|Rep:
Succinate-semialdehyde dehydrogenase (NAD(P)+) -
Plesiocystis pacifica SIR-1
Length = 541
Score = 37.5 bits (83), Expect = 0.18
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 1/115 (0%)
Frame = +1
Query: 139 KTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAE 318
+ +EKAI A+ AQ W RT ER ++ + + + A L AA K++ A
Sbjct: 45 RAVEKAIAAARRAQREWSRTSFAERRRVLRHLLDQLL-AQADDLCAAICRDTGKTLHHAM 103
Query: 319 IDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNS-LRFRGIDGFIAAISPFN 480
I + + R+ + + + + +P+ + K + + F+ + G I I+P+N
Sbjct: 104 IGEIWPIAEKLRWTLDHGETHLRPEPVRSGVLVHKRARVEFQPL-GVIGVIAPWN 157
>UniRef50_A1RDQ2 Cluster: Aldehyde dehydrogenase; n=4;
Actinobacteria (class)|Rep: Aldehyde dehydrogenase -
Arthrobacter aurescens (strain TC1)
Length = 455
Score = 37.1 bits (82), Expect = 0.24
Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Frame = +1
Query: 145 IEKAIQASVDAQTRWDRTPLTERVK-IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEI 321
+ A++ + AQ W R PL ER +W A ++A + +L +T +G+ + + E+
Sbjct: 27 VNAAVERAGAAQRAWVRKPLAERRDALWAIADAVIAHSDELALLESTDVGKPLAAARQEV 86
Query: 322 DAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
AE ++ V + ++ P+ ++T FR G +A I+P+NF
Sbjct: 87 LGVAECFKYYAGTVDKILGDTI--PVDGGVSMT-----FREPLGVVAVIAPWNF 133
>UniRef50_Q75TD2 Cluster: Aldehyde dehydrogenase family; n=14;
Bacillaceae|Rep: Aldehyde dehydrogenase family -
Geobacillus kaustophilus
Length = 478
Score = 36.7 bits (81), Expect = 0.31
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Frame = +1
Query: 79 YQVMPHDHSKK-IAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGA 255
Y + +S++ IA+ A+E+ +++AI A+ A+ P ER I + E +
Sbjct: 22 YTELKSPYSRETIAEIPVATEQEVDEAIAAAYAARQTMAAMPAHERAAILERVGEQLKAR 81
Query: 256 YRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKE-NSKYQPISESPTITKN-S 429
++ L +K +I A+ + A I ++F K + + P+ +P +
Sbjct: 82 QEEAARLIA-LEAAKPIITAKGEVA-RTIQTYKFAAEEAKRIHGETLPLDAAPGGEHRIA 139
Query: 430 LRFRGIDGFIAAISPFNF 483
L R G I AI+PFNF
Sbjct: 140 LTVREPIGVIGAITPFNF 157
>UniRef50_O66573 Cluster: Aldehyde dehydrogenase; n=1; Aquifex
aeolicus|Rep: Aldehyde dehydrogenase - Aquifex aeolicus
Length = 476
Score = 36.3 bits (80), Expect = 0.41
Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 3/152 (1%)
Frame = +1
Query: 37 IVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERV 216
++I G+ + + E + P+ K I + EK +EKAI+ + + ER
Sbjct: 6 MLIGGEWVDKEEKIEVIYPYTR-KPIGRVPKGDEKDVEKAIERAKEGFKEIFSLTAYERY 64
Query: 217 KIWQTAAELMAGAYRQSLNAATI-LGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQ 393
+I AA+L+ + + +G++ + E+ A + + F + N +
Sbjct: 65 EILMRAAQLLKERAEEFAKTLVLEVGKTIREARTEVQRAIQTLIFSAEEAK--RVNGETF 122
Query: 394 PISESPTITKNSLRF--RGIDGFIAAISPFNF 483
PI P K L F R G ++AI+PFNF
Sbjct: 123 PIDAHPN-GKGKLGFYIRVPVGIVSAITPFNF 153
>UniRef50_Q97BQ6 Cluster: Betaine aldehyde dehydrogenase; n=2;
Thermoplasmatales|Rep: Betaine aldehyde dehydrogenase -
Thermoplasma volcanium
Length = 498
Score = 36.3 bits (80), Expect = 0.41
Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 6/153 (3%)
Frame = +1
Query: 40 VIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTR-WDRTPLTERV 216
+I G G+ P D S IA Y+A + KAI +S D+ + W + L+ER
Sbjct: 10 IINGTEEMVGDESIVKSPVDGSP-IASVYFADRDAVSKAIDSSYDSYYKVWSKFTLSERK 68
Query: 217 KIWQTAAELMAG-----AYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKEN 381
K+ A+ + A +SLN L QS + +I E + +F F E
Sbjct: 69 KLLAKLADRIQEKSERYATLESLNTGKTLRQS---MLMDIPLGIEHLRYFATETEFKMER 125
Query: 382 SKYQPISESPTITKNSLRFRGIDGFIAAISPFN 480
P E P + +++ + G + AI+P+N
Sbjct: 126 QITHP--EYPD-SHGIVQYVPM-GVVGAITPWN 154
>UniRef50_Q13XQ3 Cluster: Aldehyde dehydrogenase; n=7;
Burkholderiales|Rep: Aldehyde dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 485
Score = 35.5 bits (78), Expect = 0.72
Identities = 36/153 (23%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Frame = +1
Query: 40 VIAGK--NITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTER 213
+IAG+ G+ + P D + ++ + + AIQA+ A +W RTP+T R
Sbjct: 11 LIAGEWTESVSGKTFANINPADTRDVVGQFQASVVADAQAAIQAASSAFAQWRRTPVTAR 70
Query: 214 VKIWQTAAELM---AGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENS 384
+I AA+ + A + Q L G+ + + EI +A+++ F+ +
Sbjct: 71 ARIVNKAADWLESHADTFAQELTREE--GKPLAQSRDEILRSAQVLRFYAVEAQSFTGET 128
Query: 385 KYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
E T+ R G + I+P+NF
Sbjct: 129 FPSDDPEQHVYTQ-----REPLGVVTVITPWNF 156
>UniRef50_Q9URW9 Cluster: Aldehyde dehydrogenase; n=20;
Ascomycota|Rep: Aldehyde dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 496
Score = 35.5 bits (78), Expect = 0.72
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +1
Query: 112 IAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILG 291
IAK Y A EK I+ A++++ +A W + P +E+ ++ AEL + +L A +
Sbjct: 47 IAKVYLAGEKEIDYAVKSAKEAFKTWKKVPGSEKGELLMKLAEL-TEKHADTLAAIEAMD 105
Query: 292 QSKSVI---QAEIDAAAELIDF 348
K ++ + ++D L+ +
Sbjct: 106 SGKPLVSNARGDVDGTIALLRY 127
>UniRef50_Q1IRG5 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=3; Bacteria|Rep: Methylmalonate-semialdehyde
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 490
Score = 35.1 bits (77), Expect = 0.96
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 1/117 (0%)
Frame = +1
Query: 145 IEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATIL-GQSKSVIQAEI 321
+ +A++A+ A W TP +R++ +LM + + TI G++ + + E+
Sbjct: 51 VNEAVRAAAAAWPAWRETPPGDRIQYIFKLKQLMEEHFEEIARTVTIENGKTLTEARGEV 110
Query: 322 DAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAI 492
E ++ + + + + IS + + +R G +AAI+PFNF A+
Sbjct: 111 RRGIENVEV-ACGIPLMMQGYNLENISRGI----DEIMYRHPIGVVAAITPFNFPAM 162
>UniRef50_A0QUC9 Cluster: Aldehyde dehydrogenase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Aldehyde dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 480
Score = 35.1 bits (77), Expect = 0.96
Identities = 41/151 (27%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = +1
Query: 43 IAGKNITEGEPRYQVM--PHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERV 216
I G+ + EGE + P D +++A + +E+A+QA+ +A R PL R+
Sbjct: 16 INGEWVAEGENGTTTLTAPFD-GRELAVIPVGGRRDVERAVQAAHNA--RRTGLPLDRRL 72
Query: 217 KIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKE-NSKYQ 393
I + A +A A + A L +K + A + ID +F+V + S+
Sbjct: 73 TILEAVAASIA-ARSEDFARAIALECAKPIKTARAEVL-RAIDTIKFSVAAARTLGSESV 130
Query: 394 PISESPT-ITKNSLRFRGIDGFIAAISPFNF 483
P+ + K + R G +AAI+PFNF
Sbjct: 131 PLDATAAGAGKVTFTKRVPVGVVAAIAPFNF 161
>UniRef50_Q16SX1 Cluster: Mitogen activated protein kinase kinase
kinase 4, mapkkk4, mekk4; n=1; Aedes aegypti|Rep:
Mitogen activated protein kinase kinase kinase 4,
mapkkk4, mekk4 - Aedes aegypti (Yellowfever mosquito)
Length = 1431
Score = 35.1 bits (77), Expect = 0.96
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +1
Query: 166 SVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNA-ATILGQSKSVIQA--EIDAAAE 336
S+D + R R ++ ++WQT A + Q+ +A T+ Q K + QA EIDA E
Sbjct: 211 SID-KDRTSRNVISTEERLWQTHANDLIWLELQAWHADRTVEQQDKILCQARNEIDALLE 269
Query: 337 LIDFFRFNVHFLKENS 384
I FRF H + NS
Sbjct: 270 EIMNFRFQRHLARMNS 285
>UniRef50_Q7NGY2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase;
n=12; Cyanobacteria|Rep: 1-pyrroline-5-carboxylate
dehydrogenase - Gloeobacter violaceus
Length = 996
Score = 34.7 bits (76), Expect = 1.3
Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
Frame = +1
Query: 43 IAGKNITEGEPRYQVM-PHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVK 219
+ G G P V P + + A + ++A++ + A W +T R +
Sbjct: 508 VVGGKARRGLPTLSVPNPAEPGTVLGALGLADAELADEAVKVAHTAWLSWSKTTPEARAR 567
Query: 220 IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPI 399
+ AELM R +L A + K +++ D +E IDF R+ + + +
Sbjct: 568 LLGRLAELME-QQRSALTAWIVYETGKPWRESDAD-VSEAIDFCRYYGRQILKLTAQAQH 625
Query: 400 SESPTITKNSLRFRGIDGFIAAISPFNF 483
+ P T N +R G A I+P+NF
Sbjct: 626 RDVPGET-NGYHYRS-RGVAAVIAPWNF 651
>UniRef50_Q5SJP9 Cluster: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenaseiheyensis HTE831]'; n=2;
Thermus thermophilus|Rep:
5-carboxymethyl-2-hydroxymuconate semialdehyde
dehydrogenaseiheyensis HTE831]' - Thermus thermophilus
(strain HB8 / ATCC 27634 / DSM 579)
Length = 515
Score = 34.7 bits (76), Expect = 1.3
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 136 EKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELM-AGAYRQSLNAATILGQSKSVIQ 312
E+ +++A +A+ +A RW RT ER + AEL+ A ++ GQ +++
Sbjct: 63 EREVDRAAKAAHEAFQRWSRTKAKERKRYLLRIAELIEKHADELAVMECLDAGQVLRIVR 122
Query: 313 AEIDAAAELIDFF 351
A++ AAE F+
Sbjct: 123 AQVARAAENFAFY 135
>UniRef50_A3ER29 Cluster: NAD-dependent aldehyde dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: NAD-dependent
aldehyde dehydrogenase - Leptospirillum sp. Group II UBA
Length = 502
Score = 34.7 bits (76), Expect = 1.3
Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 4/150 (2%)
Frame = +1
Query: 46 AGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIW 225
+G+N P +++P K + A +E+A++ + + + P R +I
Sbjct: 26 SGENRRTYFPFSRLLPVPGGKDVWSVDQAERTDLEEALRDAGNTRRIMRDLPRFRRSRIL 85
Query: 226 QTAAELMAGAYRQSLNAATI--LGQSKSVIQAEIDAAAELIDFFRFNVHFLKE-NSKYQP 396
+ + L+ +R+ L + +G+ S + E+D AA FR H + + + P
Sbjct: 86 ENVSRLLE-EHREPLAKLIVQEVGKPLSAARFEVDRAAST---FRTAAHAAADFGTSWMP 141
Query: 397 ISESPT-ITKNSLRFRGIDGFIAAISPFNF 483
P I N L R GF+ A++P+NF
Sbjct: 142 GDSVPQGIGMNGLVERIPKGFVLAVTPYNF 171
>UniRef50_A3BFM0 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 1657
Score = 34.7 bits (76), Expect = 1.3
Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Frame = +1
Query: 64 EGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAEL 243
E +P + H + + +Y + +K IQA +A + DR LT K +QTAA L
Sbjct: 111 ENDPTLKGRVHQSDAREMQRFY--REYYKKYIQALQNAADKADRALLT---KAYQTAAVL 165
Query: 244 MAGAYRQSLNAATILGQSKSVIQAEIDAAAELID----FFRFNVHFLKENSKYQPISESP 411
+ L A + QS V QA +D ++ + + +N+ L S YQPI + P
Sbjct: 166 F-----EVLKAVNV-SQSVEVDQAILDTHNKVEEKKKLYVPYNILPLDPESTYQPIMQYP 219
Query: 412 TI--TKNSLR-FRGI 447
I N+LR RG+
Sbjct: 220 EIQAAVNALRNIRGL 234
>UniRef50_Q4J9S9 Cluster: Aldehyde dehydrogenase; n=1; Sulfolobus
acidocaldarius|Rep: Aldehyde dehydrogenase - Sulfolobus
acidocaldarius
Length = 493
Score = 34.7 bits (76), Expect = 1.3
Identities = 34/157 (21%), Positives = 68/157 (43%), Gaps = 5/157 (3%)
Frame = +1
Query: 28 DVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQAS---VDAQTRWDRT 198
+V +I G+ E Y+ P++ + K A E +E+AI + D +
Sbjct: 3 EVKSIINGEERRSDEYIYRECPYNIDTSVTKINVAKESDVEEAIDVAREFFDKDKNGWVS 62
Query: 199 PLTERVKIWQTAAELMAGAYRQSLNAATI--LGQSKSVIQAEIDAAAELIDFFRFNVHFL 372
R K+ AE + G Q+L+ + +G + +++AAA++ +++ +
Sbjct: 63 NYKARDKVLFRIAEKIRGEI-QTLSRLLVEEIGMPIRQARVQVNAAADVFEYYAGFGSKI 121
Query: 373 KENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+ SK+ P + I K + G + I+P+NF
Sbjct: 122 YDTSKFLPSKDMVQIIKEPV------GVVGLITPWNF 152
>UniRef50_O32507 Cluster: Succinate-semialdehyde dehydrogenase
[NADP+]; n=8; Bacteria|Rep: Succinate-semialdehyde
dehydrogenase [NADP+] - Deinococcus radiodurans
Length = 477
Score = 34.7 bits (76), Expect = 1.3
Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +1
Query: 112 IAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATI-L 288
+ + + I I+ + A W + P+TER I + AAELM + + T+ +
Sbjct: 26 VKTFPFLESAEIPALIERADQAYREWGQRPVTERAAIMRRAAELMLERTDELASLITLEM 85
Query: 289 GQSKSVIQAEIDAAAELIDFF 351
G+ + E+ AA +++++
Sbjct: 86 GKLLREAKGEVALAASILNYY 106
>UniRef50_Q89N88 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=10; Bacteria|Rep: Methylmalonate-semialdehyde
dehydrogenase - Bradyrhizobium japonicum
Length = 498
Score = 33.9 bits (74), Expect = 2.2
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 1/127 (0%)
Frame = +1
Query: 115 AKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNA-ATILG 291
AK AS+ + A++ + AQ W T R ++ EL+ Y + A G
Sbjct: 33 AKVALASKAEVRAAVENARAAQPEWAATNPQRRARVMMKFVELVQRDYDKLAELLAREHG 92
Query: 292 QSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAIS 471
++ + +I E+ +F H +K +Y P I S+R + + G +A I+
Sbjct: 93 KTVPDAKGDIQRGLEVAEFACGIPHLMK--GEYTE-GAGPGIDIYSMR-QAL-GVVAGIT 147
Query: 472 PFNFTAI 492
PFNF A+
Sbjct: 148 PFNFPAM 154
>UniRef50_Q74E56 Cluster: Aldehyde dehydrogenase family protein;
n=3; Deltaproteobacteria|Rep: Aldehyde dehydrogenase
family protein - Geobacter sulfurreducens
Length = 475
Score = 33.9 bits (74), Expect = 2.2
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Frame = +1
Query: 37 IVIAGKNITEGEPRYQVM-PHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTER 213
+++ G+ + P +V+ P+D S I A+ + ++ AI+A+ P R
Sbjct: 7 VLVGGEWTGDDRPGIEVVNPYDDSV-IGVVPEATNEDVDHAIRAAQAGFAEMSALPAYRR 65
Query: 214 VKIWQTAAELMAGAYRQSLNA-ATILGQSKSVIQAEIDAAAELIDFFRF-NVHFLKENSK 387
I +EL+ + A G+S AE D +AE FRF ++ + +
Sbjct: 66 SDILDRTSELIKRDREEIAEIIAREAGKSWKFALAEADRSAET---FRFASLEARNAHGE 122
Query: 388 YQPISESPTIT-KNSLRFRGIDGFIAAISPFNF 483
P+ SP + R G I AI+PFNF
Sbjct: 123 IVPMDASPVSAGRFGFYLRTPIGVIGAIAPFNF 155
>UniRef50_Q5HLA7 Cluster: Aldehyde dehydrogenase family protein;
n=5; Staphylococcus|Rep: Aldehyde dehydrogenase family
protein - Staphylococcus epidermidis (strain ATCC 35984
/ RP62A)
Length = 479
Score = 33.9 bits (74), Expect = 2.2
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Frame = +1
Query: 130 ASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVI 309
A+E+ + AI+ S AQ W+R P R + + L+ R + + Q K++
Sbjct: 42 ATEEEVNDAIEKSQQAQLEWERVPQPTRAEHVKLLIPLLE-KNRDEIAQLYVKEQGKTLT 100
Query: 310 QA--EIDAAAELIDF 348
QA EID + ID+
Sbjct: 101 QAYGEIDKSISFIDY 115
>UniRef50_P25553 Cluster: Aldehyde dehydrogenase A; n=57;
Bacteria|Rep: Aldehyde dehydrogenase A - Escherichia
coli (strain K12)
Length = 479
Score = 33.9 bits (74), Expect = 2.2
Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 4/154 (2%)
Frame = +1
Query: 34 PIVIAGKNIT-EGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTE 210
P+ I G+ +T G+ V+ I++ + KAI A+ AQ W+ P E
Sbjct: 8 PMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERAQPEWEALPAIE 67
Query: 211 RVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQ--AEIDAAAELIDFFRFNVHFLKENS 384
R W ++ AG ++ + ++ + IQ AE++ A D+ + + +
Sbjct: 68 RAS-W--LRKISAGIRERASEISALIVEEGGKIQQLAEVEVAF-TADYIDYMAEWAR--- 120
Query: 385 KYQ-PISESPTITKNSLRFRGIDGFIAAISPFNF 483
+Y+ I +S +N L F+ G I P+NF
Sbjct: 121 RYEGEIIQSDRPGENILLFKRALGVTTGILPWNF 154
>UniRef50_Q0C0P8 Cluster: Succinylglutamic semialdehyde
dehydrogenase; n=4; Alphaproteobacteria|Rep:
Succinylglutamic semialdehyde dehydrogenase - Hyphomonas
neptunium (strain ATCC 15444)
Length = 484
Score = 33.5 bits (73), Expect = 2.9
Identities = 30/118 (25%), Positives = 55/118 (46%)
Frame = +1
Query: 130 ASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVI 309
A+ + ++ A+ ++ A + W RTP+ ER+ I + AE + G + A K++
Sbjct: 36 ANAEDVKAAVASAQAAFSGWARTPVAERISILERYAEEL-GKRAGEIAEAISRDMGKALW 94
Query: 310 QAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
++ +AA + +V LKE + + E ++ L R G +A PFNF
Sbjct: 95 DSQAEAAT-MKAKIAVSVAALKERAGER--DEPAAFGQSRLTHRP-HGVMAVFGPFNF 148
>UniRef50_Q22MH3 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 2162
Score = 33.5 bits (73), Expect = 2.9
Identities = 19/66 (28%), Positives = 38/66 (57%)
Frame = -1
Query: 216 YAFSQRSAVPTSLSIDRRLNRLFNCFFTGIVIFSYLF*VIMGHHLISWLTFCNIFSGNYN 37
YA SQ+ +P L+ + LN+ + +F +F+ + + H++S L FC +++ +YN
Sbjct: 1792 YAESQK--IPDYLTYIK-LNKKVSPYFFSTFLFNKIVDLYSEEHILS-LLFCTVYTEDYN 1847
Query: 36 WYVFNY 19
+ F+Y
Sbjct: 1848 YRFFDY 1853
>UniRef50_UPI0000ECD688 Cluster: Histone-lysine N-methyltransferase
SETDB2 (EC 2.1.1.43) (SET domain bifurcated 2) (Chronic
lymphocytic leukemia deletion region gene 8 protein).;
n=1; Gallus gallus|Rep: Histone-lysine
N-methyltransferase SETDB2 (EC 2.1.1.43) (SET domain
bifurcated 2) (Chronic lymphocytic leukemia deletion
region gene 8 protein). - Gallus gallus
Length = 569
Score = 33.1 bits (72), Expect = 3.9
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +1
Query: 22 IEDVPIVIAGKNITEGEPRYQ-VMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRT 198
+ +V V+ G++I E +P+ Q V+ D S + ++ ++ IEK+ S +A + R
Sbjct: 60 LTNVNDVLDGEDIQEPKPKSQRVVTDDSSGNSVEGSHSKKEKIEKSDSESEEASSEIQRV 119
Query: 199 PLTERVKIWQTAAELMA 249
PL R +I + ++ ++
Sbjct: 120 PLNPRYRIHKCSSACLS 136
>UniRef50_Q39H94 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=25; Proteobacteria|Rep: Methylmalonate-semialdehyde
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 506
Score = 33.1 bits (72), Expect = 3.9
Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 3/155 (1%)
Frame = +1
Query: 28 DVPIVIAGKNITEGEPRYQ-VMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPL 204
DV + G + R+Q V+ + + + A + +++A+ ++ A W TP
Sbjct: 12 DVGHYVDGAPVAGRSGRFQDVLNPALGRAVRRVALADDNEVQQAVASANAAFPAWAATPP 71
Query: 205 TERVKIWQTAAELMAGAYRQSLNAATILGQSK--SVIQAEIDAAAELIDFFRFNVHFLKE 378
R ++ +LM +R +L A K S Q E+ ++I+F LK
Sbjct: 72 IRRARVMHRFLQLM-NEHRDALAAIITAEHGKVFSDAQGEVARGIDIIEFACGVPQLLKG 130
Query: 379 NSKYQPISESPTITKNSLRFRGIDGFIAAISPFNF 483
+ ++ + ++ R G +A I+PFNF
Sbjct: 131 D-----FTDQVSTGIDNWTMRQPLGVVAGITPFNF 160
>UniRef50_Q6GVP0 Cluster: Possible polyketide synthase; n=15;
Actinomycetales|Rep: Possible polyketide synthase -
Mycobacterium avium
Length = 2124
Score = 33.1 bits (72), Expect = 3.9
Identities = 15/40 (37%), Positives = 24/40 (60%)
Frame = +1
Query: 226 QTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELID 345
++ AE + + + LN AT+ G S V+ E+DA EL+D
Sbjct: 697 RSRAEQLIAPWGERLNIATVNGISAVVVSGEVDALTELLD 736
>UniRef50_A0LKD3 Cluster: Aldehyde dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Aldehyde
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 528
Score = 33.1 bits (72), Expect = 3.9
Identities = 36/167 (21%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
Frame = +1
Query: 1 LKRT-ASVIEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDA 177
L RT A + + +++ GK++ + P D + + + A+ A+ +A
Sbjct: 29 LARTRARLGREYGMLVNGKDLFAVDKFEDRSPADTEVILGVFQKGGPREAHAAVAAAREA 88
Query: 178 QTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRF 357
+W RTP ER + + AA+ + + A L K+ ++A + AAE D R+
Sbjct: 89 FPKWSRTPWRERAALLRKAADRIDDRI-FDIGVAMALEVGKNRMEA-LGDAAETADLIRY 146
Query: 358 NVHFLKENSKYQPISESPTITKNSLRFRGID-----GFIAAISPFNF 483
+ ++ + + ++E R + G ISPFN+
Sbjct: 147 SCERMEAGNGF--VAEMGRDPLQGFDSRNVSVLRPYGVWLVISPFNY 191
>UniRef50_Q97YT9 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=2; Sulfolobus|Rep: Methylmalonate-semialdehyde
dehydrogenase - Sulfolobus solfataricus
Length = 492
Score = 33.1 bits (72), Expect = 3.9
Identities = 27/128 (21%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = +1
Query: 112 IAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILG 291
IA+ ++++ +E+AIQ++ +A +W P+T R++ + A + Y +++ +
Sbjct: 43 IAEVPFSAKDEVEEAIQSAQEAFEKWREVPITTRIQ-YLFALKNRLEEYSETIARIIVQN 101
Query: 292 QSKSVIQAEID--AAAELIDFFRFNVHFLKENSKYQPISE--SPTITKNSLRFRGIDGFI 459
K++ +A D E ++ + L + +S+ T+ + L G
Sbjct: 102 HGKTIQEARGDMRRTIENVEAAISAAYTLYKGEHLDQVSQEVDETVVREPL------GVF 155
Query: 460 AAISPFNF 483
I+PFNF
Sbjct: 156 GIITPFNF 163
>UniRef50_Q99708 Cluster: Retinoblastoma-binding protein 8; n=27;
Amniota|Rep: Retinoblastoma-binding protein 8 - Homo
sapiens (Human)
Length = 897
Score = 32.7 bits (71), Expect = 5.1
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +1
Query: 259 RQSLNAATILGQSKSV-IQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSLR 435
+ S N AT++ ++ + +Q E + + H L+ N K QP ES T++SLR
Sbjct: 248 KSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLR 307
Query: 436 F 438
F
Sbjct: 308 F 308
>UniRef50_UPI000050FFD5 Cluster: COG1012: NAD-dependent aldehyde
dehydrogenases; n=1; Brevibacterium linens BL2|Rep:
COG1012: NAD-dependent aldehyde dehydrogenases -
Brevibacterium linens BL2
Length = 189
Score = 32.3 bits (70), Expect = 6.8
Identities = 31/151 (20%), Positives = 56/151 (37%)
Frame = +1
Query: 40 VIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVK 219
+ G + Y V+ + + + A+ + KA + AQ W +TP ER
Sbjct: 15 IFTGAWTNGADESYDVIEPATGQTLGRLGAANADDVNKAATRAAAAQKEWAKTPPAERAA 74
Query: 220 IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPI 399
+ + A L A + + + + I A+ + F L + K Q +
Sbjct: 75 VLRRAGALWA---EHAEEISDWIVRESGGIPAKAGLEVSSAEQICFESSALPSHPKGQVL 131
Query: 400 SESPTITKNSLRFRGIDGFIAAISPFNFTAI 492
+ + S R G ++ I+PFNF I
Sbjct: 132 TSNEPRWSFSRRVPA--GVVSVIAPFNFPLI 160
>UniRef50_Q72KD3 Cluster: Aldehyde dehydrogenase; n=2; Thermus
thermophilus|Rep: Aldehyde dehydrogenase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 530
Score = 32.3 bits (70), Expect = 6.8
Identities = 34/149 (22%), Positives = 59/149 (39%), Gaps = 1/149 (0%)
Frame = +1
Query: 40 VIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLTERVK 219
++ G+ + EG + P D +A++ A + + KA + +A W RTP R +
Sbjct: 17 LVGGEEVLEGPLLERRNPSDREDVVARFPEADKDLVRKAALKAREAFAEWSRTPAPIRGQ 76
Query: 220 IWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSK-YQP 396
+ +++ + +L + K+ +A D E ID F F E + Y
Sbjct: 77 VLFNLVKILE-REKPTLTRLMVREVGKTPKEAAGD-VQEAIDTALF---FASEGRRLYGQ 131
Query: 397 ISESPTITKNSLRFRGIDGFIAAISPFNF 483
S K FR G + I+ NF
Sbjct: 132 TVPSEMRDKELFTFRRPLGVVGIITAGNF 160
>UniRef50_Q6A9P5 Cluster: Putative immunogenic protein antigen 84;
n=1; Propionibacterium acnes|Rep: Putative immunogenic
protein antigen 84 - Propionibacterium acnes
Length = 361
Score = 32.3 bits (70), Expect = 6.8
Identities = 21/68 (30%), Positives = 35/68 (51%)
Frame = +1
Query: 151 KAIQASVDAQTRWDRTPLTERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQAEIDAA 330
KA + +VDAQTR +R + RV + ++ + A R + +A T + ++AE D
Sbjct: 232 KAHELTVDAQTRAERIESSARVNAEKLTSDAKSNADRVNADAQTRRTELFRELEAERDNL 291
Query: 331 AELIDFFR 354
A +D R
Sbjct: 292 AGRVDHLR 299
>UniRef50_A5KNY9 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC 27756
Length = 1129
Score = 32.3 bits (70), Expect = 6.8
Identities = 16/57 (28%), Positives = 28/57 (49%)
Frame = +1
Query: 253 AYRQSLNAATILGQSKSVIQAEIDAAAELIDFFRFNVHFLKENSKYQPISESPTITK 423
A+ +LNAA K Q E+D A +++ + +K+ ++ QP+ P TK
Sbjct: 1034 AFETALNAAKETAADKDAAQTEVDNALNVLNAAVAKLEKVKDPNQQQPVQPQPEQTK 1090
>UniRef50_Q4Q7X4 Cluster: Dynein heavy chain, putative; n=10;
Trypanosomatidae|Rep: Dynein heavy chain, putative -
Leishmania major
Length = 4225
Score = 32.3 bits (70), Expect = 6.8
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 13/145 (8%)
Frame = +1
Query: 109 KIAKYYYASEKTIEKAIQASVDAQTR-WDRTPLT-ERVKIWQTAAELMAGAYRQSLNAAT 282
++A AS T+ + VDA+ W+ K+ A+ AY SL A
Sbjct: 1904 EVADLAVASPATVSRCGMVYVDAEDLPWNAVACQWSETKLAAAGAQPQCRAYILSLFDAY 1963
Query: 283 I---------LGQSKSVIQA-EIDAAAELIDFFRFNVHFLKENSKYQPISESPTITKNSL 432
+ L S S+I A +I+ L D F +H K P+ E+P + + +
Sbjct: 1964 VEKGLTWLRQLPASASLISAGDINVVQSLCDLFTALMHVNKVQLMADPVGEAPPPSDDPM 2023
Query: 433 RFRGIDGFIAAISPFNFT-AIGGNL 504
FR + AI F+F +IGGN+
Sbjct: 2024 -FRERNEICNAIFAFSFVWSIGGNV 2047
>UniRef50_A7HAX3 Cluster: Methylmalonate-semialdehyde dehydrogenase;
n=1; Anaeromyxobacter sp. Fw109-5|Rep:
Methylmalonate-semialdehyde dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 492
Score = 31.9 bits (69), Expect = 8.9
Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 3/157 (1%)
Frame = +1
Query: 31 VPIVIAGK-NITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQTRWDRTPLT 207
+P+++ G E V+ + +A+ ++ A++A+ A W TP+
Sbjct: 16 LPLLVDGAARPAEAAEAAPVLEPATGRTLAQVPLCGPADVDTAVRAAAAAFPAWRATPVP 75
Query: 208 ERVKIWQTAAELMAGAYRQSLNAATILGQSKSVIQA--EIDAAAELIDFFRFNVHFLKEN 381
ERV++ L+ + +L A+ K + A E+ E++D F + L +
Sbjct: 76 ERVQVLFRYKALLE-REQDALAASVSRENGKLLADARNEVRRGIEVVD-FACGMPTLAQG 133
Query: 382 SKYQPISESPTITKNSLRFRGIDGFIAAISPFNFTAI 492
+ I+ +S +R G +A I PFNF A+
Sbjct: 134 RTVEGIARG----VDSHTWRVPVGVVAGICPFNFPAM 166
>UniRef50_A2F7J4 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1381
Score = 31.9 bits (69), Expect = 8.9
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 7/71 (9%)
Frame = +1
Query: 265 SLNAATILGQSKSVIQAEIDAAAEL--IDFFRFNVHF-LKENSKYQ----PISESPTITK 423
SL IL ++ IQAEID++ ++ + FNV+F +K+ +K + IS S +T
Sbjct: 273 SLLCIDILKNEQNHIQAEIDSSFQILGVSSQSFNVNFEVKDFTKLEITVNTISNSENVTL 332
Query: 424 NSLRFRGIDGF 456
+ L++R I F
Sbjct: 333 DILKYRNIPAF 343
>UniRef50_Q8NF91 Cluster: Nesprin-1; n=45; Eukaryota|Rep: Nesprin-1 -
Homo sapiens (Human)
Length = 8797
Score = 31.9 bits (69), Expect = 8.9
Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = +1
Query: 4 KRTASV-IEDVPIVIAGKNITEGEPRYQVMPHDHSKKIAKYYYASEKTIEKAIQASVDAQ 180
KRT S+ ++ +V I G Q++ +K I + E T+E+ I+ +
Sbjct: 1387 KRTESIAVQAENLVKEASEIPLGPQNKQLL-QQQAKSIKEQVKKLEDTLEEDIKTMEMVK 1445
Query: 181 TRWDRTPLT-ERVKIWQTAAELMAGAYRQSLNAATI-LGQSKSVIQAEIDA 327
T+WD E + +W T E A S +A + + Q K IQ EI++
Sbjct: 1446 TKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQ-EIES 1495
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.131 0.373
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 486,011,198
Number of Sequences: 1657284
Number of extensions: 8920731
Number of successful extensions: 24868
Number of sequences better than 10.0: 80
Number of HSP's better than 10.0 without gapping: 24247
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24844
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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