Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31919
(516 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z67743-1|CAA91556.1| 789|Homo sapiens CLC-7 chloride channel pr... 146 4e-35
BC012737-1|AAH12737.1| 805|Homo sapiens chloride channel 7 prot... 146 4e-35
BC006158-1|AAH06158.1| 453|Homo sapiens CLCN7 protein protein. 146 4e-35
AL031600-1|CAB53065.1| 758|Homo sapiens chloride channel 7 prot... 146 4e-35
AF224741-1|AAF34711.1| 805|Homo sapiens chloride channel protei... 146 4e-35
AE006467-8|AAK61282.1| 812|Homo sapiens putative chloride chann... 146 4e-35
X83378-1|CAA58292.1| 869|Homo sapiens putative chloride channel... 112 8e-25
D28475-1|BAA05836.4| 872|Homo sapiens KIAA0046 protein. 112 8e-25
BC117424-1|AAI17425.1| 869|Homo sapiens chloride channel 6 prot... 112 8e-25
BC117420-1|AAI17421.1| 869|Homo sapiens chloride channel 6 prot... 112 8e-25
AL953897-20|CAI15895.1| 869|Homo sapiens chloride channel 6 pro... 112 8e-25
AL953897-19|CAI15894.1| 953|Homo sapiens chloride channel 6 pro... 112 8e-25
AL021155-11|CAI23406.1| 869|Homo sapiens chloride channel 6 pro... 112 8e-25
AL021155-10|CAI23405.1| 953|Homo sapiens chloride channel 6 pro... 112 8e-25
AF009257-1|AAB69287.1| 869|Homo sapiens putative chloride chann... 112 8e-25
X78520-2|CAA55281.1| 762|Homo sapiens chloride channel 3 protein. 56 6e-08
X78520-1|CAA55280.1| 820|Homo sapiens chloride channel 3 protein. 56 6e-08
AF172729-1|AAD51034.1| 818|Homo sapiens chloride channel 3 prot... 56 6e-08
AF029346-1|AAB95161.1| 818|Homo sapiens chloride channel protei... 56 6e-08
AB019542-1|BAC54560.1| 810|Homo sapiens clcn3e protein. 56 6e-08
X91906-1|CAA63000.1| 746|Homo sapiens voltage-gated chloride io... 54 3e-07
BC130431-1|AAI30432.1| 746|Homo sapiens CLCN5 protein protein. 54 3e-07
BC130429-1|AAI30430.1| 746|Homo sapiens CLCN5 protein protein. 54 3e-07
AL663118-1|CAI41555.1| 746|Homo sapiens chloride channel 5 (nep... 54 3e-07
X77197-1|CAA54417.1| 760|Homo sapiens chloride channel protein. 53 5e-07
BC130278-1|AAI30279.1| 760|Homo sapiens chloride channel 4 prot... 53 5e-07
BC036068-1|AAH36068.1| 760|Homo sapiens chloride channel 4 prot... 53 5e-07
AF170492-1|AAD50981.1| 760|Homo sapiens chloride channel CLC4 p... 53 5e-07
AB019432-1|BAA77327.1| 760|Homo sapiens chloride channel protei... 53 5e-07
S77770-1|AAB34722.2| 898|Homo sapiens voltage-gated chloride ch... 52 1e-06
AF026004-1|AAB88807.1| 898|Homo sapiens chloride channel protei... 52 1e-06
Z25884-1|CAA81103.1| 988|Homo sapiens human ClC-1 muscle chlori... 46 8e-05
Z25753-1|CAB56792.1| 703|Homo sapiens skeletal muscle chloride ... 46 8e-05
Z25587-1|CAA80996.1| 988|Homo sapiens human ClC-1 muscle chlori... 46 8e-05
BC113495-1|AAI13496.1| 988|Homo sapiens chloride channel 1, ske... 46 8e-05
BC112156-1|AAI12157.1| 988|Homo sapiens chloride channel 1, ske... 46 8e-05
Z30644-1|CAA83121.1| 687|Homo sapiens chloride channel (putativ... 40 0.004
S80315-1|AAB35898.1| 687|Homo sapiens ClC chloride channel ClC-... 40 0.004
BC020873-1|AAH20873.1| 462|Homo sapiens CLCNKB protein protein. 40 0.004
AL355994-13|CAI16141.1| 517|Homo sapiens chloride channel Kb pr... 40 0.004
AL355994-12|CAI16140.1| 687|Homo sapiens chloride channel Kb pr... 40 0.004
BC004946-1|AAH04946.1| 261|Homo sapiens Unknown (protein for IM... 40 0.005
Z30643-1|CAA83120.1| 687|Homo sapiens chloride channel (putativ... 40 0.007
BC053869-1|AAH53869.1| 686|Homo sapiens chloride channel Ka pro... 40 0.007
BC048282-1|AAH48282.1| 687|Homo sapiens chloride channel Ka pro... 40 0.007
AL355994-10|CAI16138.1| 686|Homo sapiens chloride channel Ka pr... 40 0.007
AL355994-9|CAI16137.1| 687|Homo sapiens chloride channel Ka pro... 40 0.007
BC072004-1|AAH72004.1| 881|Homo sapiens CLCN2 protein protein. 37 0.036
BC021578-1|AAH21578.1| 387|Homo sapiens CLCN2 protein protein. 37 0.036
X81836-1|CAA57430.1| 260|Homo sapiens Dents disease candidate p... 31 3.2
AK096088-1|BAC04699.1| 632|Homo sapiens protein ( Homo sapiens ... 29 9.7
>Z67743-1|CAA91556.1| 789|Homo sapiens CLC-7 chloride channel
protein protein.
Length = 789
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 434 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 493
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 494 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 553
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 554 MMEATSNVTYGFPIMLVLMTAKI 576
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 575 KIVGDVFIEGLYDMHIQLQSVPFLHWE 601
>BC012737-1|AAH12737.1| 805|Homo sapiens chloride channel 7
protein.
Length = 805
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 450 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 509
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 510 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 569
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 570 MMEATSNVTYGFPIMLVLMTAKI 592
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 591 KIVGDVFIEGLYDMHIQLQSVPFLHWE 617
>BC006158-1|AAH06158.1| 453|Homo sapiens CLCN7 protein protein.
Length = 453
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 98 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 157
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 158 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 217
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 218 MMEATSNVTYGFPIMLVLMTAKI 240
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 239 KIVGDVFIEGLYDMHIQLQSVPFLHWE 265
>AL031600-1|CAB53065.1| 758|Homo sapiens chloride channel 7
protein.
Length = 758
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 403 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 462
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 463 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 522
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 523 MMEATSNVTYGFPIMLVLMTAKI 545
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 544 KIVGDVFIEGLYDMHIQLQSVPFLHWE 570
>AF224741-1|AAF34711.1| 805|Homo sapiens chloride channel protein 7
protein.
Length = 805
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 450 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 509
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 510 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 569
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 570 MMEATSNVTYGFPIMLVLMTAKI 592
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 591 KIVGDVFIEGLYDMHIQLQSVPFLHWE 617
>AE006467-8|AAK61282.1| 812|Homo sapiens putative chloride channel
protein 7 protein.
Length = 812
Score = 146 bits (354), Expect = 4e-35
Identities = 68/143 (47%), Positives = 94/143 (65%), Gaps = 1/143 (0%)
Frame = +1
Query: 1 LQLYCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAV 180
LQL+C GEYN++AA +F TPE SV S HDP GSY P ++ +F + YF L+ WT+GL V
Sbjct: 450 LQLFCADGEYNSMAAAFFNTPEKSVVSLFHDPPGSYNPLTLGLFTLVYFFLACWTYGLTV 509
Query: 181 SSGLFIPNLLTGAAWGRLLAISIQYMLPSKT-INPAKYXXXXXXXXXXXXXRMTISLTVI 357
S+G+FIP+LL GAAWGRL IS+ Y+ + +P KY RMT+SLTVI
Sbjct: 510 SAGVFIPSLLIGAAWGRLFGISLSYLTGAAIWADPGKYALMGAAAQLGGIVRMTLSLTVI 569
Query: 358 IIETTGQISNALPIMITLVVAQM 426
++E T ++ PIM+ L+ A++
Sbjct: 570 MMEATSNVTYGFPIMLVLMTAKI 592
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 591 KIVGDVFIEGLYDMHIQLQSVPFLHWE 617
>X83378-1|CAA58292.1| 869|Homo sapiens putative chloride channel
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>D28475-1|BAA05836.4| 872|Homo sapiens KIAA0046 protein.
Length = 872
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 432 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 490
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 491 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 550
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 551 TNEITYGLPIMVTLMVAK 568
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 568 KWTGDFFNKGIYDIHVGLRGVPLLEWE 594
>BC117424-1|AAI17425.1| 869|Homo sapiens chloride channel 6
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>BC117420-1|AAI17421.1| 869|Homo sapiens chloride channel 6
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>AL953897-20|CAI15895.1| 869|Homo sapiens chloride channel 6
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>AL953897-19|CAI15894.1| 953|Homo sapiens chloride channel 6
protein.
Length = 953
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>AL021155-11|CAI23406.1| 869|Homo sapiens chloride channel 6
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>AL021155-10|CAI23405.1| 953|Homo sapiens chloride channel 6
protein.
Length = 953
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>AF009257-1|AAB69287.1| 869|Homo sapiens putative chloride channel
protein.
Length = 869
Score = 112 bits (269), Expect = 8e-25
Identities = 55/138 (39%), Positives = 86/138 (62%)
Frame = +1
Query: 10 YCEXGEYNALAAIWFQTPEASVRSFLHDPMGSYKPWSILVFVVCYFLLSTWTFGLAVSSG 189
+C YN +A ++F E+++ H G++ P ++ +F V YFLL+ WT+G++V SG
Sbjct: 429 FCPNDTYNDMATLFFNPQESAILQLFHQD-GTFSPVTLALFFVLYFLLACWTYGISVPSG 487
Query: 190 LFIPNLLTGAAWGRLLAISIQYMLPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIET 369
LF+P+LL GAA+GRL+A ++ + I + RMTISLTVI+IE+
Sbjct: 488 LFVPSLLCGAAFGRLVANVLKSYIGLGHIYSGTFALIGAAAFLGGVVRMTISLTVILIES 547
Query: 370 TGQISNALPIMITLVVAQ 423
T +I+ LPIM+TL+VA+
Sbjct: 548 TNEITYGLPIMVTLMVAK 565
Score = 52.0 bits (119), Expect = 1e-06
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
KW GDFFN+GIYDI++ L GVPLL WE
Sbjct: 565 KWTGDFFNKGIYDIHVGLRGVPLLEWE 591
>X78520-2|CAA55281.1| 762|Homo sapiens chloride channel 3 protein.
Length = 762
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYM------------ 258
W + + ++ +++ +TFG+ V SGLFIP++ GA GR++ I+++ +
Sbjct: 443 WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKE 502
Query: 259 ---LPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + I P Y RMT+SL VI+ E TG + +P+M ++ ++
Sbjct: 503 WCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSK 560
Score = 33.1 bits (72), Expect = 0.59
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+GD F EGIY+ +I+L G P L
Sbjct: 560 KWVGDAFGREGIYEAHIRLNGYPFL 584
>X78520-1|CAA55280.1| 820|Homo sapiens chloride channel 3 protein.
Length = 820
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYM------------ 258
W + + ++ +++ +TFG+ V SGLFIP++ GA GR++ I+++ +
Sbjct: 501 WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKE 560
Query: 259 ---LPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + I P Y RMT+SL VI+ E TG + +P+M ++ ++
Sbjct: 561 WCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSK 618
Score = 33.1 bits (72), Expect = 0.59
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+GD F EGIY+ +I+L G P L
Sbjct: 618 KWVGDAFGREGIYEAHIRLNGYPFL 642
>AF172729-1|AAD51034.1| 818|Homo sapiens chloride channel 3
protein.
Length = 818
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYM------------ 258
W + + ++ +++ +TFG+ V SGLFIP++ GA GR++ I+++ +
Sbjct: 501 WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKE 560
Query: 259 ---LPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + I P Y RMT+SL VI+ E TG + +P+M ++ ++
Sbjct: 561 WCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSK 618
Score = 33.1 bits (72), Expect = 0.59
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+GD F EGIY+ +I+L G P L
Sbjct: 618 KWVGDAFGREGIYEAHIRLNGYPFL 642
>AF029346-1|AAB95161.1| 818|Homo sapiens chloride channel protein 3
protein.
Length = 818
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYM------------ 258
W + + ++ +++ +TFG+ V SGLFIP++ GA GR++ I+++ +
Sbjct: 501 WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKE 560
Query: 259 ---LPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + I P Y RMT+SL VI+ E TG + +P+M ++ ++
Sbjct: 561 WCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSK 618
Score = 33.1 bits (72), Expect = 0.59
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+GD F EGIY+ +I+L G P L
Sbjct: 618 KWVGDAFGREGIYEAHIRLNGYPFL 642
>AB019542-1|BAC54560.1| 810|Homo sapiens clcn3e protein.
Length = 810
Score = 56.4 bits (130), Expect = 6e-08
Identities = 31/118 (26%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYM------------ 258
W + + ++ +++ +TFG+ V SGLFIP++ GA GR++ I+++ +
Sbjct: 443 WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAYYHHDWFIFKE 502
Query: 259 ---LPSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + I P Y RMT+SL VI+ E TG + +P+M ++ ++
Sbjct: 503 WCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTGGLEYIVPLMAAVMTSK 560
Score = 33.1 bits (72), Expect = 0.59
Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+GD F EGIY+ +I+L G P L
Sbjct: 560 KWVGDAFGREGIYEAHIRLNGYPFL 584
>X91906-1|CAA63000.1| 746|Homo sapiens voltage-gated chloride ion
channel protein.
Length = 746
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GRLL + ++ +
Sbjct: 429 WQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNS 488
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ I P Y RMT+SL VI+ E TG + +P+M + ++
Sbjct: 489 WCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSK 546
Score = 29.9 bits (64), Expect = 5.5
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D EGIYD +I+L G P L
Sbjct: 546 KWVADALGREGIYDAHIRLNGYPFL 570
>BC130431-1|AAI30432.1| 746|Homo sapiens CLCN5 protein protein.
Length = 746
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GRLL + ++ +
Sbjct: 429 WQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNS 488
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ I P Y RMT+SL VI+ E TG + +P+M + ++
Sbjct: 489 WCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSK 546
Score = 29.9 bits (64), Expect = 5.5
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D EGIYD +I+L G P L
Sbjct: 546 KWVADALGREGIYDAHIRLNGYPFL 570
>BC130429-1|AAI30430.1| 746|Homo sapiens CLCN5 protein protein.
Length = 746
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GRLL + ++ +
Sbjct: 429 WQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNS 488
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ I P Y RMT+SL VI+ E TG + +P+M + ++
Sbjct: 489 WCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSK 546
Score = 29.9 bits (64), Expect = 5.5
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D EGIYD +I+L G P L
Sbjct: 546 KWVADALGREGIYDAHIRLNGYPFL 570
>AL663118-1|CAI41555.1| 746|Homo sapiens chloride channel 5
(nephrolithiasis 2, X-linked, Dent disease) protein.
Length = 746
Score = 54.0 bits (124), Expect = 3e-07
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GRLL + ++ +
Sbjct: 429 WQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNS 488
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ I P Y RMT+SL VI+ E TG + +P+M + ++
Sbjct: 489 WCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSK 546
Score = 29.9 bits (64), Expect = 5.5
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D EGIYD +I+L G P L
Sbjct: 546 KWVADALGREGIYDAHIRLNGYPFL 570
>X77197-1|CAA54417.1| 760|Homo sapiens chloride channel protein.
Length = 760
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GR++ I ++ +
Sbjct: 443 WQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWYYFRN 502
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + P Y RMT+SL VI+ E TG + +P+M V ++
Sbjct: 503 WCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSK 560
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D F EGIY+ +I L G P L
Sbjct: 560 KWVADAFGKEGIYEAHIHLNGYPFL 584
>BC130278-1|AAI30279.1| 760|Homo sapiens chloride channel 4
protein.
Length = 760
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GR++ I ++ +
Sbjct: 443 WQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWIIFRN 502
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + P Y RMT+SL VI+ E TG + +P+M V ++
Sbjct: 503 WCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSK 560
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D F EGIY+ +I L G P L
Sbjct: 560 KWVADAFGKEGIYEAHIHLNGYPFL 584
>BC036068-1|AAH36068.1| 760|Homo sapiens chloride channel 4
protein.
Length = 760
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GR++ I ++ +
Sbjct: 443 WQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWIIFRN 502
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + P Y RMT+SL VI+ E TG + +P+M V ++
Sbjct: 503 WCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSK 560
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D F EGIY+ +I L G P L
Sbjct: 560 KWVADAFGKEGIYEAHIHLNGYPFL 584
>AF170492-1|AAD50981.1| 760|Homo sapiens chloride channel CLC4
protein.
Length = 760
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GR++ I ++ +
Sbjct: 443 WQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWIIFRN 502
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + P Y RMT+SL VI+ E TG + +P+M V ++
Sbjct: 503 WCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSK 560
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D F EGIY+ +I L G P L
Sbjct: 560 KWVADAFGKEGIYEAHIHLNGYPFL 584
>AB019432-1|BAA77327.1| 760|Homo sapiens chloride channel protein 4
protein.
Length = 760
Score = 53.2 bits (122), Expect = 5e-07
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Frame = +1
Query: 115 WSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYML----------- 261
W + + ++ +++ +TFG+ + SGLFIP++ GA GR++ I ++ +
Sbjct: 443 WQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWIIFRN 502
Query: 262 ----PSKTINPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
+ + P Y RMT+SL VI+ E TG + +P+M V ++
Sbjct: 503 WCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSK 560
Score = 30.3 bits (65), Expect = 4.2
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D F EGIY+ +I L G P L
Sbjct: 560 KWVADAFGKEGIYEAHIHLNGYPFL 584
>S77770-1|AAB34722.2| 898|Homo sapiens voltage-gated chloride
channel protein.
Length = 898
Score = 52.0 bits (119), Expect = 1e-06
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP------SKT-- 273
++++F++ F +S + V G F+P + GAA+GRL+ S+ P S T
Sbjct: 434 TLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYR 493
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
I P Y T+S VI+ E TGQI++ LP+MI +++A + LQ
Sbjct: 494 IVPGGYAVVGAAALAGAVTH-TVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQ 549
>AF026004-1|AAB88807.1| 898|Homo sapiens chloride channel protein
protein.
Length = 898
Score = 52.0 bits (119), Expect = 1e-06
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP------SKT-- 273
++++F++ F +S + V G F+P + GAA+GRL+ S+ P S T
Sbjct: 434 TLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYR 493
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
I P Y T+S VI+ E TGQI++ LP+MI +++A + LQ
Sbjct: 494 IVPGGYAVVGAAALAGAVTH-TVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQ 549
>Z25884-1|CAA81103.1| 988|Homo sapiens human ClC-1 muscle chloride
channel protein.
Length = 988
Score = 46.0 bits (104), Expect = 8e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Frame = +1
Query: 121 ILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLPS--------KTI 276
I +F V F +S + + G F+P + GAA+GRL+ + + P I
Sbjct: 460 IFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKI 519
Query: 277 NPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
P Y T+S VI E TGQI++ LP+M+ +++A M + LQ
Sbjct: 520 LPGGYAVIGAAALTGAVSH-TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574
>Z25753-1|CAB56792.1| 703|Homo sapiens skeletal muscle chloride
channel protein protein.
Length = 703
Score = 46.0 bits (104), Expect = 8e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Frame = +1
Query: 121 ILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLPS--------KTI 276
I +F V F +S + + G F+P + GAA+GRL+ + + P I
Sbjct: 175 IFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKI 234
Query: 277 NPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
P Y T+S VI E TGQI++ LP+M+ +++A M + LQ
Sbjct: 235 LPGGYAVIGAAALTGAVSH-TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 289
>Z25587-1|CAA80996.1| 988|Homo sapiens human ClC-1 muscle chloride
channel protein.
Length = 988
Score = 46.0 bits (104), Expect = 8e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Frame = +1
Query: 121 ILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLPS--------KTI 276
I +F V F +S + + G F+P + GAA+GRL+ + + P I
Sbjct: 460 IFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKI 519
Query: 277 NPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
P Y T+S VI E TGQI++ LP+M+ +++A M + LQ
Sbjct: 520 LPGGYAVIGAAALTGAVSH-TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574
>BC113495-1|AAI13496.1| 988|Homo sapiens chloride channel 1,
skeletal muscle (Thomsen disease, autosomal dominant)
protein.
Length = 988
Score = 46.0 bits (104), Expect = 8e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Frame = +1
Query: 121 ILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLPS--------KTI 276
I +F V F +S + + G F+P + GAA+GRL+ + + P I
Sbjct: 460 IFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKI 519
Query: 277 NPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
P Y T+S VI E TGQI++ LP+M+ +++A M + LQ
Sbjct: 520 LPGGYAVIGAAALTGAVSH-TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574
>BC112156-1|AAI12157.1| 988|Homo sapiens chloride channel 1,
skeletal muscle (Thomsen disease, autosomal dominant)
protein.
Length = 988
Score = 46.0 bits (104), Expect = 8e-05
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Frame = +1
Query: 121 ILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLPS--------KTI 276
I +F V F +S + + G F+P + GAA+GRL+ + + P I
Sbjct: 460 IFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKI 519
Query: 277 NPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
P Y T+S VI E TGQI++ LP+M+ +++A M + LQ
Sbjct: 520 LPGGYAVIGAAALTGAVSH-TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574
>Z30644-1|CAA83121.1| 687|Homo sapiens chloride channel (putative)
protein.
Length = 687
Score = 40.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRL ++ ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFEVTGQIVHALPVLMAVLAA 508
>S80315-1|AAB35898.1| 687|Homo sapiens ClC chloride channel ClC-K2
protein.
Length = 687
Score = 40.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRL ++ ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFEVTGQIVHALPVLMAVLAA 508
>BC020873-1|AAH20873.1| 462|Homo sapiens CLCNKB protein protein.
Length = 462
Score = 40.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRL ++ ++ P +
Sbjct: 273 TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNP 332
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 333 IMPGGYALAGAAAFSGAVTH-TISTALLAFEVTGQIVHALPVLMAVLAA 380
>AL355994-13|CAI16141.1| 517|Homo sapiens chloride channel Kb
protein.
Length = 517
Score = 40.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRL ++ ++ P +
Sbjct: 232 TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNP 291
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 292 IMPGGYALAGAAAFSGAVTH-TISTALLAFEVTGQIVHALPVLMAVLAA 339
>AL355994-12|CAI16140.1| 687|Homo sapiens chloride channel Kb
protein.
Length = 687
Score = 40.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRL ++ ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFEVTGQIVHALPVLMAVLAA 508
>BC004946-1|AAH04946.1| 261|Homo sapiens Unknown (protein for
IMAGE:3615790) protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.005
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 422 KWIGDFFNEGIYDIYIQLAGVPLLPWE 502
K +GD F EG+YD++IQL VP L WE
Sbjct: 47 KIVGDVFIEGLYDMHIQLQSVPFLHWE 73
Score = 36.7 bits (81), Expect = 0.048
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 331 RMTISLTVIIIETTGQISNALPIMITLVVAQM 426
RMT+SLTVI++E T ++ PIM+ L+ A++
Sbjct: 17 RMTLSLTVIMMEATSNVTYGFPIMLVLMTAKI 48
>Z30643-1|CAA83120.1| 687|Homo sapiens chloride channel (putative)
protein.
Length = 687
Score = 39.5 bits (88), Expect = 0.007
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRLL ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFELTGQIVHALPVLMAVLAA 508
>BC053869-1|AAH53869.1| 686|Homo sapiens chloride channel Ka
protein.
Length = 686
Score = 39.5 bits (88), Expect = 0.007
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRLL ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFELTGQIVHALPVLMAVLAA 508
>BC048282-1|AAH48282.1| 687|Homo sapiens chloride channel Ka
protein.
Length = 687
Score = 39.5 bits (88), Expect = 0.007
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRLL ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFELTGQIVHALPVLMAVLAA 508
>AL355994-10|CAI16138.1| 686|Homo sapiens chloride channel Ka
protein.
Length = 686
Score = 39.5 bits (88), Expect = 0.007
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRLL ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFELTGQIVHALPVLMAVLAA 508
>AL355994-9|CAI16137.1| 687|Homo sapiens chloride channel Ka
protein.
Length = 687
Score = 39.5 bits (88), Expect = 0.007
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Frame = +1
Query: 118 SILVFVVCYFLLSTWTFGLAVSSGLFIPNLLTGAAWGRLLAISIQYMLP--------SKT 273
++ F+V F + + + +G F+P + GAA GRLL ++ P +
Sbjct: 401 TLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNP 460
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVA 420
I P Y TIS ++ E TGQI +ALP+++ ++ A
Sbjct: 461 IMPGGYALAGAAAFSGAVTH-TISTALLAFELTGQIVHALPVLMAVLAA 508
>BC072004-1|AAH72004.1| 881|Homo sapiens CLCN2 protein protein.
Length = 881
Score = 37.1 bits (82), Expect = 0.036
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +1
Query: 337 TISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
T+S VI+ E TGQI++ LP+MI +++A + LQ
Sbjct: 497 TVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQ 532
>BC021578-1|AAH21578.1| 387|Homo sapiens CLCN2 protein protein.
Length = 387
Score = 37.1 bits (82), Expect = 0.036
Identities = 16/36 (44%), Positives = 25/36 (69%)
Frame = +1
Query: 337 TISLTVIIIETTGQISNALPIMITLVVAQMDRRFLQ 444
T+S VI+ E TGQI++ LP+MI +++A + LQ
Sbjct: 38 TVSTAVIVFELTGQIAHILPVMIVVILANAVAQSLQ 73
>X81836-1|CAA57430.1| 260|Homo sapiens Dents disease candidate
protein.
Length = 260
Score = 30.7 bits (66), Expect = 3.2
Identities = 15/50 (30%), Positives = 23/50 (46%)
Frame = +1
Query: 274 INPAKYXXXXXXXXXXXXXRMTISLTVIIIETTGQISNALPIMITLVVAQ 423
I P Y RMT+SL VI+ E TG + +P+M + ++
Sbjct: 11 ITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSK 60
Score = 29.9 bits (64), Expect = 5.5
Identities = 13/25 (52%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = +2
Query: 422 KWIGDFFN-EGIYDIYIQLAGVPLL 493
KW+ D EGIYD +I+L G P L
Sbjct: 60 KWVADALGREGIYDAHIRLNGYPFL 84
>AK096088-1|BAC04699.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ38769 fis, clone KIDNE2015556, highly similar to
RENAL SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2. ).
Length = 632
Score = 29.1 bits (62), Expect = 9.7
Identities = 16/72 (22%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Frame = +1
Query: 46 IWFQTPEASVRSFLHDPMGS----YKPWSILVFVVCYFLLSTWTFGLAVSSGLFIPNLLT 213
+W+ P + + + +G Y+ +++L +VC+ LL + FG++++ + +
Sbjct: 480 LWYPVPCTRLPIRMAEALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQVMVGV-- 537
Query: 214 GAAWGRLLAISI 249
G +G LLA +
Sbjct: 538 GTPFGALLAFVV 549
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,966,423
Number of Sequences: 237096
Number of extensions: 1820685
Number of successful extensions: 3507
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 3282
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3471
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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