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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV31786
         (516 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH...   252   4e-66
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   252   4e-66
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s...   248   6e-65
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC...   192   3e-48
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla...   189   3e-47
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;...   186   2e-46
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica...   184   8e-46
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   176   2e-43
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ...   173   2e-42
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...   146   3e-34
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   142   3e-33
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   142   4e-33
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   140   2e-32
UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone...   139   4e-32
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   138   5e-32
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ...   137   2e-31
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   136   3e-31
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E...   135   5e-31
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr...   135   5e-31
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who...   133   2e-30
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   133   2e-30
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil...   131   8e-30
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   131   8e-30
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   130   2e-29
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut...   128   6e-29
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   128   6e-29
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   128   7e-29
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1...   127   1e-28
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   127   1e-28
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen...   126   4e-28
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...   124   9e-28
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...   123   2e-27
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000...   122   4e-27
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...   120   2e-26
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   120   3e-26
UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   119   5e-26
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   118   1e-25
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   118   1e-25
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte...   117   2e-25
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   117   2e-25
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,...   116   2e-25
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p...   116   2e-25
UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E...   115   6e-25
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   115   7e-25
UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;...   115   7e-25
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n...   114   1e-24
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   114   1e-24
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   113   2e-24
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   113   2e-24
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...   112   4e-24
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   112   5e-24
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   111   7e-24
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   111   9e-24
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   110   2e-23
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   110   2e-23
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   105   6e-22
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   103   2e-21
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone...   102   4e-21
UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;...   102   6e-21
UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   102   6e-21
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   101   1e-20
UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...   101   1e-20
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s...   100   2e-20
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone...   100   4e-20
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo...    99   5e-20
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ...    97   2e-19
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma...    97   3e-19
UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone...    96   4e-19
UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello...    95   8e-19
UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni...    93   3e-18
UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon...    91   1e-17
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ...    86   4e-16
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ...    70   4e-11
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh...    65   8e-10
UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;...    41   0.019
UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu...    40   0.045
UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura...    39   0.059
UniRef50_A6S3R6 Cluster: Putative uncharacterized protein; n=1; ...    34   1.7  
UniRef50_Q00160 Cluster: Uncharacterized gene 37 protein; n=1; I...    34   2.2  
UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6; Alph...    33   5.1  
UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza sativa|...    33   5.1  
UniRef50_Q2HW29 Cluster: Putative uncharacterized protein; n=1; ...    33   5.1  
UniRef50_UPI0000546B3D Cluster: PREDICTED: hypothetical protein;...    32   6.8  
UniRef50_Q1QBJ3 Cluster: Glycosyl transferase, group 1; n=1; Psy...    32   6.8  
UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia int...    32   6.8  
UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; ...    32   6.8  
UniRef50_A3UUK2 Cluster: Lipase/acylhydrolase family protein; n=...    32   6.8  
UniRef50_A5KMP2 Cluster: Putative uncharacterized protein; n=1; ...    32   8.9  

>UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH
           protein - Homo sapiens (Human)
          Length = 640

 Score =  252 bits (617), Expect = 4e-66
 Identities = 116/170 (68%), Positives = 138/170 (81%), Gaps = 1/170 (0%)
 Frame = +2

Query: 2   VFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT 181
           VF LP+TTFIG +E ALPLREI+ RLE AYC +IG+EFMFIN LEQC WIRQ+ E P + 
Sbjct: 91  VFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIM 150

Query: 182 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 361
           +   ++KR +LARL RST FE FL +KWSSEKRFGLEGCE+LIPA+K +ID S++ GV+ 
Sbjct: 151 QFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDY 210

Query: 362 IIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTY 508
           +IMGMPHRGRLNVLANV RK L Q+F QF + LEA D+GSGDVKYHLG Y
Sbjct: 211 VIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMY 260


>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial precursor; n=77; Eumetazoa|Rep:
           2-oxoglutarate dehydrogenase E1 component, mitochondrial
           precursor - Homo sapiens (Human)
          Length = 1002

 Score =  252 bits (617), Expect = 4e-66
 Identities = 116/170 (68%), Positives = 138/170 (81%), Gaps = 1/170 (0%)
 Frame = +2

Query: 2   VFKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT 181
           VF LP+TTFIG +E ALPLREI+ RLE AYC +IG+EFMFIN LEQC WIRQ+ E P + 
Sbjct: 185 VFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIM 244

Query: 182 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 361
           +   ++KR +LARL RST FE FL +KWSSEKRFGLEGCE+LIPA+K +ID S++ GV+ 
Sbjct: 245 QFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDY 304

Query: 362 IIMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTY 508
           +IMGMPHRGRLNVLANV RK L Q+F QF + LEA D+GSGDVKYHLG Y
Sbjct: 305 VIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMY 354


>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
           shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
           SCAF14563, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1054

 Score =  248 bits (607), Expect = 6e-65
 Identities = 114/171 (66%), Positives = 138/171 (80%), Gaps = 1/171 (0%)
 Frame = +2

Query: 5   FKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK 184
           F+LPSTTFIG ++  LPLREI+ RLE AYC +IG+EFMFIN+++QC WIR ++E P + +
Sbjct: 185 FQLPSTTFIGGEDSTLPLREIIRRLEMAYCGHIGVEFMFINNVDQCQWIRNKIETPGIMR 244

Query: 185 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 364
                KR +LARL RST FE+FLA+KWSSEKRFGLEGCE+LIPA+K +ID S+  GV+S+
Sbjct: 245 FTDADKRTLLARLIRSTRFEDFLARKWSSEKRFGLEGCEVLIPALKTIIDESSAAGVDSV 304

Query: 365 IMGMPHRGRLNVLANVCRKPLHQLFTQF-AGLEAEDDGSGDVKYHLGTYIE 514
           IMGMPHRGRLNVLANV RK L Q+F QF   LEA D+GSGDVKYHLG Y E
Sbjct: 305 IMGMPHRGRLNVLANVIRKDLDQIFCQFDPKLEAADEGSGDVKYHLGMYHE 355


>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
           isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG33791-PC, isoform C - Apis mellifera
          Length = 980

 Score =  192 bits (469), Expect = 3e-48
 Identities = 86/170 (50%), Positives = 117/170 (68%)
 Frame = +2

Query: 5   FKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK 184
           F L   T IG  +++LPLR+IL RL Q YC ++G+E+ +I+ L   +W+R + E P    
Sbjct: 150 FPLAPFTVIGGSKRSLPLRDILIRLNQVYCGHLGLEYTYIHDLVMLDWLRDKFEIPGAWD 209

Query: 185 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 364
           + AD ++ I   + ++  FE FLA+K+ +EKRFGLEGCE  IP+M Q ++ S + GVES+
Sbjct: 210 LPADHRKFIWMNIMKAVTFEGFLARKFPTEKRFGLEGCESFIPSMNQCLETSAEHGVESV 269

Query: 365 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIE 514
           ++GM HRGRLN L NVC KPLHQL TQF  +  E  GSGDVKYHLGT+ E
Sbjct: 270 VIGMAHRGRLNTLINVCMKPLHQLLTQFHSIALEGFGSGDVKYHLGTHAE 319


>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
           Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
           sativa (Rice)
          Length = 1016

 Score =  189 bits (461), Expect = 3e-47
 Identities = 91/167 (54%), Positives = 119/167 (71%), Gaps = 7/167 (4%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR 205
           F+ E      LR +L RLEQAYC  IG E+M I   E+CNW+R R+E  N  + + D+++
Sbjct: 172 FLSENRPVQTLRSVLERLEQAYCGTIGYEYMHIPDREKCNWLRDRIETVNAREYSYDRRQ 231

Query: 206 LILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHR 385
           ++L RL  ST FE+FLA+KW++ KRFGLEG E LIP MK++ D +  LGVESI++GMPHR
Sbjct: 232 VMLDRLMWSTQFESFLAQKWTTAKRFGLEGAETLIPGMKEMFDRAADLGVESIVIGMPHR 291

Query: 386 GRLNVLANVCRKPLHQLFTQFAG--LEAED-----DGSGDVKYHLGT 505
           GRLNVL NV RKPL Q+F++F+G    AE+      G+GDVKYHLGT
Sbjct: 292 GRLNVLGNVVRKPLRQIFSEFSGGTKPAEEGEGLYTGTGDVKYHLGT 338


>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 1012

 Score =  186 bits (454), Expect = 2e-46
 Identities = 84/170 (49%), Positives = 115/170 (67%)
 Frame = +2

Query: 5   FKLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK 184
           F L + T IG   + LPLREI+ RL + YC ++G+E+++I+      W+R + E P   +
Sbjct: 189 FPLGTITVIGGDRETLPLREIIKRLNKVYCGHLGLEYIYIHDSTVLEWLRYKFEIPGAWE 248

Query: 185 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 364
           + AD ++ I   + ++  FENFLAKK+ +EKRFGLEGCE  I +M Q ++ S++ GVE++
Sbjct: 249 LAADHRKWIWVNIMKAVTFENFLAKKYGTEKRFGLEGCESFIASMAQCLETSSEQGVETV 308

Query: 365 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIE 514
            +GM HRGRLN L NVC KPLHQL TQF  +  E  GSGDVKYHLGT  E
Sbjct: 309 AIGMAHRGRLNTLVNVCSKPLHQLLTQFKPISLEGLGSGDVKYHLGTCAE 358


>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
           CaKGD1 2-oxoglutarate dehydrogenase; n=4;
           Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
           albicans CaKGD1 2-oxoglutarate dehydrogenase -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 997

 Score =  184 bits (449), Expect = 8e-46
 Identities = 82/154 (53%), Positives = 114/154 (74%)
 Frame = +2

Query: 41  EKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILAR 220
           +K+L LREI++  E+ YC + G+E++ I S EQC+W+R+R+E P   K + D+KR IL R
Sbjct: 177 KKSLTLREIISNCERLYCQSYGVEYIHIPSKEQCDWLRERIEIPEPYKYSPDEKRQILDR 236

Query: 221 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 400
           +  S  FE+FLA K+ ++KRFGLEG E ++P MK +ID S + GVE I++GMPHRGRLN+
Sbjct: 237 VIWSCSFESFLASKFPNDKRFGLEGAESVVPGMKAMIDTSVEFGVEDIVIGMPHRGRLNM 296

Query: 401 LANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           L+NV RKP   +F++F G    D+GSGDVKYHLG
Sbjct: 297 LSNVVRKPNESIFSEFTGSREFDEGSGDVKYHLG 330


>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
           2-oxoglutarate dehydrogenase E1 component, mitochondrial
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 1014

 Score =  176 bits (429), Expect = 2e-43
 Identities = 80/161 (49%), Positives = 117/161 (72%), Gaps = 2/161 (1%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR 205
           F  + +  + L+EI++ LE+ YC++ G+++  I S ++C+W+R+R+E P   +   DQKR
Sbjct: 187 FARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKR 246

Query: 206 LILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHR 385
            IL RLT +T FE+FL+ K+ ++KRFGLEG E ++P +K ++D S +LGVE I++GM HR
Sbjct: 247 QILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHR 306

Query: 386 GRLNVLANVCRKPLHQLFTQFAGLEAEDD--GSGDVKYHLG 502
           GRLNVL+NV RKP   +F++F G  A DD  GSGDVKYHLG
Sbjct: 307 GRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLG 347


>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1013

 Score =  173 bits (422), Expect = 2e-42
 Identities = 83/164 (50%), Positives = 111/164 (67%), Gaps = 4/164 (2%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR 205
           F+  K+    LR++L RL++ YC +IGIE+M I   E C+WIR + E     ++   +K 
Sbjct: 183 FLTNKQPETTLRQVLKRLKETYCGDIGIEYMHIQDREMCDWIRDKFETSQPVEIPDKEKI 242

Query: 206 LILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHR 385
            IL RL+ +  FE FL  K+ + +RFGL+GCE LIP MK +ID +T+ GVESI++GMPHR
Sbjct: 243 KILERLSWADQFEGFLGLKYRATRRFGLDGCESLIPGMKAMIDTATEDGVESIVLGMPHR 302

Query: 386 GRLNVLANVCRKPLHQLFTQFAG----LEAEDDGSGDVKYHLGT 505
           GRLNVLANV RKPL  +F +F G    +E E   +GDVKYHLGT
Sbjct: 303 GRLNVLANVVRKPLPAIFNEFNGGVISIEGEYSATGDVKYHLGT 346


>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
           decarboxylase - Lentisphaera araneosa HTCC2155
          Length = 913

 Score =  146 bits (354), Expect = 3e-34
 Identities = 70/152 (46%), Positives = 96/152 (63%), Gaps = 3/152 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRS 232
           L++I++ LE  YC++IG+E+ +  S E   W+ ++ME   N    N  QK  IL +LT+ 
Sbjct: 121 LKDIISHLEDTYCSSIGVEYRYSQSSEMRQWLHEKMESNANKPNFNKTQKMNILKKLTQG 180

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
            GFE FL  K+  +KRF LEG E  IPAM ++ +  ++LGV+  +MGM HRGRLNVLAN+
Sbjct: 181 VGFEKFLGVKYVGQKRFSLEGLEAFIPAMTELFNQGSRLGVQEFVMGMAHRGRLNVLANL 240

Query: 413 CRKPLHQLFTQFAGLEAEDD--GSGDVKYHLG 502
             K    LF +F G    DD  G GDVKYH+G
Sbjct: 241 FEKEYKALFQEFEGHALPDDVGGDGDVKYHMG 272


>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Geobacter sulfurreducens
          Length = 894

 Score =  142 bits (345), Expect = 3e-33
 Identities = 70/151 (46%), Positives = 99/151 (65%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRS 232
           LREIL  L + YC ++G+EFM I    +  W+ +RMEP  N   ++ DQK  IL +L  +
Sbjct: 118 LREILATLRETYCRSVGVEFMHIQDPAERTWLIERMEPVRNRPPVSLDQKLRILEKLREA 177

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
           + FE FL +K+  +KRF LEG E LIPA+  V++ + +LGV+ +++GM HRGRLNVLA +
Sbjct: 178 SLFEEFLHRKFLGQKRFSLEGGEALIPALDAVVERAARLGVDDLVLGMAHRGRLNVLATI 237

Query: 413 CRKPLHQLFTQFA-GLEAEDDGSGDVKYHLG 502
             KP+  +F +FA  +E    G GDVKYH G
Sbjct: 238 IGKPVENIFAEFADNVELAFVGDGDVKYHKG 268


>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           mitochondrial, putative; n=9; Plasmodium|Rep:
           2-oxoglutarate dehydrogenase E1 component,
           mitochondrial, putative - Plasmodium vivax
          Length = 1059

 Score =  142 bits (344), Expect = 4e-33
 Identities = 75/175 (42%), Positives = 103/175 (58%), Gaps = 5/175 (2%)
 Frame = +2

Query: 5   FKLPSTT-FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT 181
           F LPS T F   K++   LR +++RLEQ YC  IG E+M I      N+I +R+E     
Sbjct: 185 FDLPSITGFSSNKKETSTLRSLIDRLEQTYCGTIGFEYMHITDESVVNYIVKRIERDRKF 244

Query: 182 KMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVES 361
           + +   KR IL    R+  FEN++A K+++ KRFG++GCE LI  MK +I  +  +  ES
Sbjct: 245 QYDRKTKRKILENTARAFIFENYMAAKFATTKRFGVDGCETLITGMKALISRAAMVHTES 304

Query: 362 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDD----GSGDVKYHLGTYIE 514
           ++M M HRGRLNVL NV  KPL  +  +F G     D     +GDVKYHLG  I+
Sbjct: 305 VLMSMSHRGRLNVLFNVLHKPLENMMCEFRGKTGFTDNIWGNTGDVKYHLGVEID 359


>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=16; cellular organisms|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Robiginitalea biformata
           HTCC2501
          Length = 940

 Score =  140 bits (339), Expect = 2e-32
 Identities = 67/151 (44%), Positives = 99/151 (65%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRS 232
           LREI++ L + YC+ IG+E+M+I S E+  WI+Q +    N    + ++K+ IL +L  +
Sbjct: 139 LREIIDHLTRIYCDAIGVEYMYIRSPERVEWIQQWLNVNDNHPNFSPERKKYILRKLNEA 198

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
             FE FL  K+  +KRF LEG E LIPA+  +++ + +LGV+  +MGM HRGRLNVL N+
Sbjct: 199 VSFEGFLHTKYVGQKRFSLEGNESLIPAVDAIVERAAELGVQQFVMGMAHRGRLNVLTNI 258

Query: 413 CRKPLHQLFTQFAGLEAEDD-GSGDVKYHLG 502
             KP   +F++F G + E +   GDVKYHLG
Sbjct: 259 FGKPATDIFSEFEGKDYEQEIFDGDVKYHLG 289


>UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component;
           n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate
           dehydrogenase E1 component - Gluconobacter oxydans
           (Gluconobacter suboxydans)
          Length = 885

 Score =  139 bits (336), Expect = 4e-32
 Identities = 70/152 (46%), Positives = 98/152 (64%), Gaps = 3/152 (1%)
 Frame = +2

Query: 59  REILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTG 238
           R+++ RL +AYC     EFM +    Q  W   R+E P     + D KR++LA LTR+ G
Sbjct: 100 RDLIARLRRAYCGTTAAEFMHLQDPAQRQWWIDRLENP-APGPSLDPKRILLA-LTRAEG 157

Query: 239 FENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCR 418
           FE F  K++   +RFGLEG E +I A++ +ID + +  + S+ +GMPHRGRLNV+AN+ R
Sbjct: 158 FEQFCQKRFMGMRRFGLEGGESVIVALRTLIDAAAQDDIRSVSLGMPHRGRLNVMANILR 217

Query: 419 KPLHQLFTQFAGLEAEDD---GSGDVKYHLGT 505
           KP   +F++FAG   + D   GSGDVKYHLGT
Sbjct: 218 KPFAAIFSEFAGASFKPDTIEGSGDVKYHLGT 249


>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Corynebacterium glutamicum (Brevibacterium
           flavum)
          Length = 1257

 Score =  138 bits (335), Expect = 5e-32
 Identities = 71/160 (44%), Positives = 98/160 (61%), Gaps = 2/160 (1%)
 Frame = +2

Query: 32  GEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLI 211
           G KE  + LRE+L+RL  AY   +G E+  I   ++  W++ R+E        A+QK  I
Sbjct: 465 GGKE-TMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQK-YI 522

Query: 212 LARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGR 391
           L +L  +  FENFL  K+  +KRF LEG E LIP M   ID +   G++ +++GMPHRGR
Sbjct: 523 LQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGR 582

Query: 392 LNVLANVCRKPLHQLFTQFAGL--EAEDDGSGDVKYHLGT 505
           LNVL N+  KPL  +F +F G   + +  GSGDVKYHLG+
Sbjct: 583 LNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGS 622


>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 1304

 Score =  137 bits (331), Expect = 2e-31
 Identities = 71/161 (44%), Positives = 98/161 (60%), Gaps = 2/161 (1%)
 Frame = +2

Query: 32  GEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLI 211
           G+ ++ L LR+IL RL   Y   +GIE+M I   EQ  W+++R+E P     + D +R I
Sbjct: 492 GDSDQML-LRDILTRLHDTYTRTVGIEYMHIQDPEQRAWVQKRIERPYEAP-SPDAQRHI 549

Query: 212 LARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGR 391
           L  L R+  FE FL  K+  +KRF LEG E LIP +  ++  S + G+  + +GM HRGR
Sbjct: 550 LGTLIRAEAFEEFLQTKFMGQKRFSLEGGESLIPLLDHILADSARTGIHEVAIGMAHRGR 609

Query: 392 LNVLANVCRKPLHQLFTQFAG--LEAEDDGSGDVKYHLGTY 508
           LNVLAN+  K   Q+F +F G  +     GSGDVKYHLGT+
Sbjct: 610 LNVLANIAGKSYAQIFDEFEGNYMPNSVQGSGDVKYHLGTW 650


>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=3; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Salinibacter ruber (strain
           DSM 13855)
          Length = 1243

 Score =  136 bits (329), Expect = 3e-31
 Identities = 68/157 (43%), Positives = 99/157 (63%), Gaps = 3/157 (1%)
 Frame = +2

Query: 41  EKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILA 217
           E  LPLREIL+ L ++Y + +G  FM I+  E+  WI+ R+EP  N    + +++  I+ 
Sbjct: 441 EDKLPLREILSILRKSYTSKVGTAFMHISDPEEKTWIQNRIEPMRNAGSPSEEERHRIVQ 500

Query: 218 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 397
           +L  +  FE FL  K+   KRF LEG E +IP +  ++  +   GVE ++MGM HRGRLN
Sbjct: 501 KLNAAEAFERFLHTKYIGHKRFSLEGSETMIPLIDTLLSDAADEGVEEVVMGMAHRGRLN 560

Query: 398 VLANVCRKPLHQLFTQFAG-LEAE-DDGSGDVKYHLG 502
           VLAN+  KP  ++F++F G ++     GSGDVKYHLG
Sbjct: 561 VLANIIGKPYEEIFSKFEGNIDPNTTQGSGDVKYHLG 597


>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
           component; n=7; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase complex, E1 component - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 942

 Score =  135 bits (327), Expect = 5e-31
 Identities = 72/161 (44%), Positives = 93/161 (57%), Gaps = 1/161 (0%)
 Frame = +2

Query: 23  TFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT-KMNADQ 199
           +F G       LREIL  L Q YC +IG E+M I+   Q  WI+ R+E    T + +A+ 
Sbjct: 139 SFHGFSADHATLREILEALRQTYCGSIGSEYMHISDTGQKRWIQSRLESVRGTPRFSAEM 198

Query: 200 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 379
           K+ IL R T +   E FL  K+  +KRF LEG E  I AM +++ V   LG + I++GM 
Sbjct: 199 KKRILERTTAAETLEKFLHTKYVGQKRFSLEGGESTIVAMDEIVRVGGSLGAQEIVIGMA 258

Query: 380 HRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           HRGRLNVL N   K    LF +F G  A D  +GDVKYHLG
Sbjct: 259 HRGRLNVLVNTLGKSPSMLFAEFEGKAAADLTAGDVKYHLG 299


>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component; n=4;
           Bacteroidetes|Rep: Oxoglutarate dehydrogenase
           (Succinyl-transferring), E1 component - Cytophaga
           hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 946

 Score =  135 bits (327), Expect = 5e-31
 Identities = 68/155 (43%), Positives = 98/155 (63%), Gaps = 3/155 (1%)
 Frame = +2

Query: 47  ALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT-KMNADQKRLILARL 223
           A  LR+I+  L+  Y   IG E+M+I   E+  W+R ++E  ++   +  D+K+ IL++L
Sbjct: 150 AASLRKIVETLKFIYEGAIGFEYMYIRKPEKLAWLRNKIEKESLAHNLTLDEKKRILSKL 209

Query: 224 TRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVL 403
             +  FENFL  K+  +KRF LEG E  IPA+ ++I  S +LGVE +++GM HRGRLNVL
Sbjct: 210 NEAVVFENFLHTKYVGQKRFSLEGGETTIPALDKMITASAELGVEEVVIGMAHRGRLNVL 269

Query: 404 ANVCRKPLHQLFTQFAGLEAED--DGSGDVKYHLG 502
           AN+  K   Q+F +F G    D   G GDVKYH+G
Sbjct: 270 ANIMGKTYEQIFNEFEGNIKPDMTMGDGDVKYHMG 304


>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_5,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1002

 Score =  133 bits (322), Expect = 2e-30
 Identities = 66/157 (42%), Positives = 97/157 (61%), Gaps = 5/157 (3%)
 Frame = +2

Query: 50  LPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTR 229
           + LR+++N LE+AYC  I  E+M I S E+ NWIR+++E       + +QK     RL +
Sbjct: 181 MKLRDLINYLEKAYCGKISYEYMHIQSTEERNWIREQIEKFEEFLPSKEQKLKTFERLGQ 240

Query: 230 STGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLAN 409
              F  FL KK+++ KRFG+EGC+ +I  ++ ++D +   GVE I+ GM HRGRLN L N
Sbjct: 241 EHAFSTFLQKKFNTSKRFGIEGCDSMISGLQSMVDSAASAGVEYIVFGMAHRGRLNTLYN 300

Query: 410 VCRKPLHQLFTQF---AGLEAED--DGSGDVKYHLGT 505
           V +K   ++  +F    G+  ED    SGDVKYHLG+
Sbjct: 301 VFQKSPEEIMVEFQDLKGIYNEDIWGNSGDVKYHLGS 337


>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Brucella melitensis
          Length = 1004

 Score =  133 bits (322), Expect = 2e-30
 Identities = 66/151 (43%), Positives = 99/151 (65%), Gaps = 4/151 (2%)
 Frame = +2

Query: 62  EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNV-TKMNADQKRLILARLTRSTG 238
           E+L+ L++ YC  IG+EFM I+   +  WI++R+E P+       + K+ IL++L  + G
Sbjct: 197 EMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEG 256

Query: 239 FENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCR 418
           FE F+  K+   KRFGL+G E LIPA++Q++    ++G++ +++GM HRGRLNVL+ V  
Sbjct: 257 FEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMG 316

Query: 419 KPLHQLFTQF-AGLEAEDD--GSGDVKYHLG 502
           KP   +F +F  G    DD  GSGDVKYHLG
Sbjct: 317 KPHRAIFHEFKGGSYTPDDVEGSGDVKYHLG 347


>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
           oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
           oryzae
          Length = 453

 Score =  131 bits (317), Expect = 8e-30
 Identities = 66/155 (42%), Positives = 96/155 (61%), Gaps = 1/155 (0%)
 Frame = +2

Query: 41  EKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILAR 220
           EK  PL E++   E+ YC+ +GIE+M I++ EQ +WIR R+E     +   ++KR +L  
Sbjct: 128 EKPKPLWEVIAACEKTYCSTMGIEYMHISNQEQVDWIRARIEGAQRHRFTDEEKRRMLHG 187

Query: 221 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 400
           L R+T +E F+A K+ +EKRFGL+G E  IPA++  ID S + GV+ I MG+ HRGR+N+
Sbjct: 188 LVRATSWEKFVATKFPNEKRFGLDGVESYIPALETAIDRSAEHGVDKIEMGVAHRGRMNM 247

Query: 401 LANVCRKPLHQLFTQFAGLEAEDDG-SGDVKYHLG 502
           L N+  K    +F  F        G  GD+KYH G
Sbjct: 248 LYNIVGKDGASMFRDFDPKGTSSWGIPGDIKYHYG 282


>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Azotobacter vinelandii
          Length = 943

 Score =  131 bits (317), Expect = 8e-30
 Identities = 68/160 (42%), Positives = 93/160 (58%), Gaps = 1/160 (0%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKM-NADQK 202
           +IG++E  L  REIL  L++ YC  IG EF  I   EQ NW  QR+E      + + + K
Sbjct: 149 YIGKEEATL--REILQALQETYCRTIGAEFTHIVDSEQRNWFAQRLESVRGRPVYSKEAK 206

Query: 203 RLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPH 382
             +L RL+ + G E +L  K+   KRFGLEG E L+P + ++I  S   G + +++GM H
Sbjct: 207 SHLLERLSAAEGLEKYLGTKYPGTKRFGLEGGESLVPVVDEIIQRSGSYGTKEVVIGMAH 266

Query: 383 RGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           RGRLN+L N   K    LF +F G    + GSGDVKYH G
Sbjct: 267 RGRLNLLVNALGKNPRDLFDEFEGKHLVELGSGDVKYHQG 306


>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=2; Cystobacterineae|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Myxococcus xanthus (strain
           DK 1622)
          Length = 963

 Score =  130 bits (314), Expect = 2e-29
 Identities = 67/157 (42%), Positives = 98/157 (62%), Gaps = 3/157 (1%)
 Frame = +2

Query: 41  EKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILA 217
           E+ + L E+L RL + Y + IG+E+M +   E+  W+  RME   N T  + D+ R IL 
Sbjct: 160 EQRVRLTELLARLRRTYTDTIGVEYMHMLDSERRRWLMHRMESNENRTDFSPDECRHILT 219

Query: 218 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 397
           +L+ + GFE+FL  K+   KRF L+G E LIP +  + +V+T +G+  I++GM HRGRLN
Sbjct: 220 KLSYAEGFEHFLHTKYVGAKRFSLDGGEALIPMLDALGEVATGMGLREIVIGMAHRGRLN 279

Query: 398 VLANVCRKPLHQLFTQFAGLEAEDD--GSGDVKYHLG 502
           VL N+  K   Q+F++F G     D  G GDVKYH+G
Sbjct: 280 VLTNILGKQPDQIFSEFDGPRNPQDYLGRGDVKYHMG 316


>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
           Opitutaceae bacterium TAV2|Rep: Oxoglutarate
           dehydrogenase - Opitutaceae bacterium TAV2
          Length = 384

 Score =  128 bits (310), Expect = 6e-29
 Identities = 66/152 (43%), Positives = 94/152 (61%), Gaps = 3/152 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNAD-QKRLILARLTRS 232
           LR+I+  ++  YC+N+G+E+M +       W++ RME  N      + QKR IL+R+ ++
Sbjct: 126 LRDIVEAVKDTYCSNVGVEYMHVQDHAAREWLQVRMEATNNNPAFTNAQKRRILSRIHKA 185

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
             FE FL  K+  +KRF LEG E LI A+  +I+ +  +GVE  ++GM HRGRL+VLAN 
Sbjct: 186 ELFEKFLHTKYVGQKRFSLEGGETLIAALDAMIEHAPDVGVEEFVLGMAHRGRLSVLANT 245

Query: 413 CRKPLHQLFTQFAG--LEAEDDGSGDVKYHLG 502
            RKP   LF QF+   +     G GDVKYHLG
Sbjct: 246 LRKPFDVLFEQFSENYIPHTVAGDGDVKYHLG 277


>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Haemophilus influenzae
          Length = 935

 Score =  128 bits (310), Expect = 6e-29
 Identities = 63/156 (40%), Positives = 93/156 (59%), Gaps = 1/156 (0%)
 Frame = +2

Query: 38  KEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-IL 214
           K   + L E+   L++ YC +IG+EFM +  +EQ  W++ +ME      +   ++R+  L
Sbjct: 149 KRDTIKLGELAQMLKETYCGSIGLEFMHVQDMEQKMWLQSKMESLLDKPLFTSEERVNFL 208

Query: 215 ARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRL 394
             LT + G E +L  K+   KRF LEG +  IP MK++I  S++ GV  ++MGM HRGRL
Sbjct: 209 RELTAADGLERYLGAKFPGAKRFSLEGSDAFIPLMKEIIRHSSRQGVNDVVMGMAHRGRL 268

Query: 395 NVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           N+L NV  K    LF +FAG +   + +GDVKYH G
Sbjct: 269 NMLVNVLGKKPENLFDEFAG-KHSSERTGDVKYHQG 303


>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Francisella tularensis|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Francisella tularensis
           subsp. tularensis (strain FSC 198)
          Length = 941

 Score =  128 bits (309), Expect = 7e-29
 Identities = 63/154 (40%), Positives = 101/154 (65%), Gaps = 1/154 (0%)
 Frame = +2

Query: 44  KALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARL 223
           KA+PL++++N+ +  Y +NIG E+ +I + E+  W++ R+E   V  + +D K+ IL +L
Sbjct: 153 KAIPLQQVINKAKAIYESNIGYEYRYIGNKEEKLWLQDRIEDTAV--IPSDSKKWILQQL 210

Query: 224 TRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVS-TKLGVESIIMGMPHRGRLNV 400
             + G E +LA ++  +KRFGLEG E LIP+++ +++ + ++     I +GM HRGRLNV
Sbjct: 211 VAAEGLEKYLALRYVGQKRFGLEGGESLIPSLQHIVEKAVSRHSTRFIQLGMAHRGRLNV 270

Query: 401 LANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           L NV  K    LF +F G ++E   SGDVKYH+G
Sbjct: 271 LVNVMGKNPKDLFEEFEGKQSEKSLSGDVKYHMG 304


>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
           component family protein; n=1; Tetrahymena thermophila
           SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
           family protein - Tetrahymena thermophila SB210
          Length = 1054

 Score =  127 bits (307), Expect = 1e-28
 Identities = 65/156 (41%), Positives = 95/156 (60%), Gaps = 6/156 (3%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           LR++++ L+Q YCN +G ++M IN+  + +WIRQR+E     K   +Q      RL R  
Sbjct: 229 LRDLIDHLKQIYCNKVGYQYMHINNKTERDWIRQRIENAEQFKPTKEQLVRTADRLCRDY 288

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
            F  FL  K+S+ KRFG EGC+  I  +  ++D +    +E+I++GMPHRGRLN L +V 
Sbjct: 289 CFTEFLNNKFSTSKRFGSEGCDSFISGLGALVDHAADKKIENIVIGMPHRGRLNTLYSVL 348

Query: 416 RKPLHQLFTQF-----AGLEAEDDG-SGDVKYHLGT 505
           +KP   +  +F     A  + E+ G SGDVKYHLGT
Sbjct: 349 KKPAVNILAEFQDINVAKFDEENWGNSGDVKYHLGT 384


>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
           E1 component - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 963

 Score =  127 bits (307), Expect = 1e-28
 Identities = 72/166 (43%), Positives = 95/166 (57%), Gaps = 4/166 (2%)
 Frame = +2

Query: 17  STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP----PNVTK 184
           S TF G+    + LRE++N L + YC  IG E+M+     Q  W +Q++E     PN+TK
Sbjct: 155 SNTFFGKD--TMSLRELINALRETYCGTIGAEYMYATDQNQKRWWQQKLESIRSKPNLTK 212

Query: 185 MNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 364
              ++K  IL RLT + G E FL  K+  +KRF LEG E  I +M ++I      GV+ I
Sbjct: 213 ---EKKLHILDRLTAAEGLERFLHTKYVGQKRFSLEGGESFIASMDELIQQGGIKGVQEI 269

Query: 365 IMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           ++GM HRGRLNVL N   K    LF +F     ED  SGDVKYH G
Sbjct: 270 VIGMAHRGRLNVLVNSLGKVPADLFAEFDHTAPEDLPSGDVKYHQG 315


>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr13 scaffold_17, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 973

 Score =  126 bits (303), Expect = 4e-28
 Identities = 59/113 (52%), Positives = 76/113 (67%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR 205
           F+ E      LR IL RLEQAYC +IG E+M I   ++CNW+R ++E P   + N  ++ 
Sbjct: 181 FLSENRPVQTLRAILTRLEQAYCGSIGYEYMHIADRDKCNWLRDKIETPTPRQYNQQRRE 240

Query: 206 LILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESI 364
           +IL RL  ST FENFLA KW++ KRFGLEG E LIP MK++ D +  LGVESI
Sbjct: 241 VILDRLIWSTQFENFLATKWTAAKRFGLEGGETLIPGMKEMFDRAADLGVESI 293


>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
           E1 subunit - Anaeromyxobacter sp. Fw109-5
          Length = 940

 Score =  124 bits (300), Expect = 9e-28
 Identities = 59/150 (39%), Positives = 88/150 (58%), Gaps = 1/150 (0%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRS 232
           LR ++ RLE+ YC  +G+E   ++  +   W+ QRME   N   +  + KR +L ++  +
Sbjct: 143 LRGLVARLEETYCRTLGVELAHMHDADLRGWLEQRMERTRNRVSLEPEVKRRLLEKVVEA 202

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
              E +L  K+   KRF +EG E L+P  +  +D +   GV ++++GM HRGRLNVLANV
Sbjct: 203 ETLEQYLGTKFLGAKRFSVEGAEGLLPLFELAVDRAIGHGVRNVVIGMAHRGRLNVLANV 262

Query: 413 CRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
             KPL  +F +F      + G GDVKYHLG
Sbjct: 263 VGKPLRDIFAEFRDAAIINAGGGDVKYHLG 292


>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
           subunit - Solibacter usitatus (strain Ellin6076)
          Length = 1220

 Score =  123 bits (297), Expect = 2e-27
 Identities = 64/160 (40%), Positives = 92/160 (57%), Gaps = 3/160 (1%)
 Frame = +2

Query: 32  GEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRL 208
           G  +    LREIL  L Q YC  IG E+M I   EQ  W++QRMEP  N   ++ + +  
Sbjct: 406 GAPKSLATLREILETLRQTYCGKIGCEYMNIQVPEQKRWLQQRMEPEANNWLLDRETRLR 465

Query: 209 ILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRG 388
            L  +     FE+FL  ++  +KRF LEG E  +  ++++++ +    V  I++GM HRG
Sbjct: 466 TLHSVIAGEEFEHFLHSRFVGQKRFALEGGETALAILEEILERAAGRNVHEIVVGMAHRG 525

Query: 389 RLNVLANVCRKPLHQLFTQFAGL--EAEDDGSGDVKYHLG 502
           RLN+LAN   K + Q+F++F G        GSGDVKYHLG
Sbjct: 526 RLNILANTVGKDVKQIFSEFEGEIDPGSTQGSGDVKYHLG 565


>UniRef50_UPI0000DAE34D Cluster: hypothetical protein
           Rgryl_01000074; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000074 - Rickettsiella
           grylli
          Length = 929

 Score =  122 bits (295), Expect = 4e-27
 Identities = 62/150 (41%), Positives = 92/150 (61%), Gaps = 1/150 (0%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRS 232
           +  +LN L++ YC +IG E+  I    Q  W+++R+E        +A  K+ IL  L R+
Sbjct: 149 VESVLNHLKKIYCRSIGFEYEHIACHAQRTWLQERIESVTGKPDFSAKVKKNILKGLIRA 208

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
            G E FL  K+ ++KRF LEG + LIP ++ +I  +++  VE I++GM HRGRLNVL N+
Sbjct: 209 DGLEKFLGNKFVAQKRFSLEGGDSLIPLLEALITDASRAEVEEIVIGMAHRGRLNVLINI 268

Query: 413 CRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
             K   QLF +F G   +++ SGDVKYH G
Sbjct: 269 LGKSPAQLFEEFEGKMIQENRSGDVKYHKG 298


>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
           Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
           dehydrogenase E1 - Blastopirellula marina DSM 3645
          Length = 929

 Score =  120 bits (289), Expect = 2e-26
 Identities = 58/151 (38%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNV-TKMNADQKRLILARLTRS 232
           +RE+  R+++ YC ++GI+   I+      W+ + +E  +  + +  D +R IL RLT +
Sbjct: 143 VRELFERMQRVYCGDVGIQLQHIDDHVVRRWLIEEVEGDDRDSSLGRDTQRRILQRLTEA 202

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
             FE F+ KK+   K F LEG E LIP +   I    + G+  +++ MPHRGRL+VLANV
Sbjct: 203 MVFEEFVRKKYLGAKTFSLEGSETLIPLLDLAIHGFAEQGISELVLAMPHRGRLSVLANV 262

Query: 413 CRKPLHQLFTQFAGLEAEDD-GSGDVKYHLG 502
            R+P  ++F+QF   + +   G GDVKYH+G
Sbjct: 263 IRQPPREIFSQFEDADPKRHIGGGDVKYHMG 293


>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Escherichia coli (strain
           UTI89 / UPEC)
          Length = 939

 Score =  120 bits (288), Expect = 3e-26
 Identities = 62/162 (38%), Positives = 90/162 (55%)
 Frame = +2

Query: 17  STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNAD 196
           S TF G     +PL+++LN LEQA+  +   E   + + E+ NW+  R+E  N  + +A 
Sbjct: 141 SVTF-GAHTTQMPLKQLLNLLEQAWAGSQAYELAHLENREEINWLLSRIESSNAPQADAQ 199

Query: 197 QKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGM 376
                  +L  +   E +L  ++  +KRF LEG E  IPA+  +       GVE +++GM
Sbjct: 200 TCIARFEKLMAAETLERYLHTRYVGQKRFSLEGGESAIPALDTLTKRLRAQGVEEMVIGM 259

Query: 377 PHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
            HRGRLNVL N+  K   QLF +F G +    GSGDVKYH+G
Sbjct: 260 AHRGRLNVLVNLLNKDPAQLFAEFEGKQTIGSGSGDVKYHMG 301


>UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1
           component - Bacillus anthracis
          Length = 955

 Score =  119 bits (286), Expect = 5e-26
 Identities = 58/153 (37%), Positives = 94/153 (61%), Gaps = 6/153 (3%)
 Frame = +2

Query: 62  EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTG 238
           ++++RL++ Y  ++  EF  I   E+  W+ Q +E  ++ +  +++KR  +L RLT   G
Sbjct: 143 DVIHRLKEVYTQSLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEG 202

Query: 239 FENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCR 418
           FE FL K +  +KRF +EG ++L+P + +++    K GVE +++GM HRGRL+VLA+V  
Sbjct: 203 FEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLE 262

Query: 419 KPLHQLFTQF-----AGLEAEDDGSGDVKYHLG 502
           KP   +F +F      G  A    +GDVKYHLG
Sbjct: 263 KPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLG 295


>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Blochmannia floridanus
          Length = 970

 Score =  118 bits (283), Expect = 1e-25
 Identities = 64/169 (37%), Positives = 87/169 (51%), Gaps = 4/169 (2%)
 Frame = +2

Query: 20  TTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVT---KMN 190
           T  +G  +  + L  I   L++ YC  IGIE+M I  + Q  WI+   E   +      +
Sbjct: 150 TNLLGMNKGIITLNSIYKFLKKTYCGTIGIEYMHILDINQILWIQDYFESHTIEISDHFS 209

Query: 191 ADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVST-KLGVESII 367
             ++R  L  L  S   E +L  K+   KRF LEG ++LIP +K+ I  S     ++ I 
Sbjct: 210 VKEQRQFLNELIASEELERYLGIKFPGSKRFSLEGGDVLIPMLKEAIRYSVLNHNIQEIF 269

Query: 368 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIE 514
           +GMPHRGRLN L NV  K    LF +F G   +   SGDVKYH G Y E
Sbjct: 270 LGMPHRGRLNTLINVLGKNPQDLFNEFYGTNQKYTNSGDVKYHQGLYSE 318


>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Enterobacteriaceae|Rep: 2-oxoglutarate
           dehydrogenase E1 component - Buchnera aphidicola subsp.
           Schizaphis graminum
          Length = 923

 Score =  118 bits (283), Expect = 1e-25
 Identities = 60/160 (37%), Positives = 90/160 (56%), Gaps = 1/160 (0%)
 Frame = +2

Query: 26  FIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR 205
           F    +  + +R++  +L   YC +IG E+M+I +  +  WI + +E      +   +++
Sbjct: 134 FKNSSQYEIKIRDLYEQLNNKYCGSIGFEYMYIENSFEKKWITKHIELFFKENLFIKKEK 193

Query: 206 L-ILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPH 382
           +  L  +     FE +L KK+S  KRF LEG E LI  + ++I  S K  V  II+GM H
Sbjct: 194 IRFLKEILYGETFEKYLGKKFSGTKRFSLEGGETLISILHEIIRYSKKNDVSEIILGMAH 253

Query: 383 RGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           RGRLNVL NV  K    LF +F+G+    + SGDVKYH+G
Sbjct: 254 RGRLNVLVNVLNKNPQVLFNEFSGINIPKEYSGDVKYHMG 293


>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
           Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
           fastidiosa
          Length = 967

 Score =  117 bits (281), Expect = 2e-25
 Identities = 69/167 (41%), Positives = 95/167 (56%), Gaps = 5/167 (2%)
 Frame = +2

Query: 17  STTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPN-VTKMNA 193
           ST  IG + + + LR +L  L+  Y + IG EFM I+  EQ  WI +R+E        NA
Sbjct: 161 STGGIGGQPR-MKLRNLLAHLKATYTDTIGTEFMHISEFEQRQWIYRRLENVGGKIASNA 219

Query: 194 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMG 373
             ++ IL RLT + G E +L  K+  +KRF LEG + LIP M  ++  +    V+ I++G
Sbjct: 220 TNRKRILERLTAAEGLERYLHTKYVGQKRFSLEGSDTLIPLMDTLVRQAGNNDVKDIVVG 279

Query: 374 MPHRGRLNVLANVCRKPLHQLFTQFAGL--EAEDD--GSGDVKYHLG 502
           M HRGRLNVL N   K   +LF +F G    A  D   +GDVKYH+G
Sbjct: 280 MAHRGRLNVLVNTLGKNPRKLFDEFEGKFEHAHHDRAHTGDVKYHMG 326


>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           2-oxoglutarate dehydrogenase, E1 component family
           protein - Tetrahymena thermophila SB210
          Length = 992

 Score =  117 bits (281), Expect = 2e-25
 Identities = 60/157 (38%), Positives = 93/157 (59%), Gaps = 6/157 (3%)
 Frame = +2

Query: 62  EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGF 241
           EI+   ++ Y   IG E+  I ++++  W+++R+E   +   N   ++  L RL R+  F
Sbjct: 171 EIIEICKKIYTGKIGFEYYHIENVDEKLWLQKRIEDIGLKPQNNVDRKKTLERLLRNEQF 230

Query: 242 ENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRK 421
             FL  ++S+ KRFG+EGC+  I  +  ++D + + GV+S+I+GMPHRGRLN LA V  K
Sbjct: 231 NLFLKNRFSTSKRFGIEGCDSFISGLGALVDHACENGVQSLILGMPHRGRLNTLACVFNK 290

Query: 422 PLHQLFTQFAGL------EAEDDGSGDVKYHLGTYIE 514
              Q+F +F  +      +AE   SGDVKYHLG   E
Sbjct: 291 NPEQIFAEFQEIRDKSLDDAEWGNSGDVKYHLGCTTE 327


>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
           subunit; n=3; cellular organisms|Rep: Predicted
           2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
           tauri
          Length = 1210

 Score =  116 bits (280), Expect = 2e-25
 Identities = 60/147 (40%), Positives = 87/147 (59%)
 Frame = +2

Query: 62  EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGF 241
           E+  RL   YC  + +E   + S ++  W+R + E     + +   +R  LARL R+   
Sbjct: 172 ELFERLRDVYCGTMSVECNHLTSQDRKRWLRMQFES-GPERPSEKTRRKTLARLLRADML 230

Query: 242 ENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRK 421
           ENFLA+++ S KRFGLEG E LIP ++  ++ + +  VESI++GMPHRGRLNVL NV  K
Sbjct: 231 ENFLAERFPSAKRFGLEGAESLIPGLQAFVERAAERRVESIVLGMPHRGRLNVLHNVFGK 290

Query: 422 PLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           PL  +  +    +      GDV+YHLG
Sbjct: 291 PLGAISAEIVD-DRSSFLVGDVRYHLG 316


>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
           putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
           dehydrogenase subunit, putative - Trypanosoma brucei
          Length = 1008

 Score =  116 bits (280), Expect = 2e-25
 Identities = 59/159 (37%), Positives = 94/159 (59%), Gaps = 2/159 (1%)
 Frame = +2

Query: 32  GEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLI 211
           GE  K   L++I+ +L+  YC +IG EF+     +  +W  + +       ++ +++  I
Sbjct: 169 GENVKEATLQQIVEKLQMMYCGSIGFEFLLTEGDDVRHWFHKEILK-TFEPLSKEERIHI 227

Query: 212 LARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGR 391
           L  + +S GFE F+  K+ ++ RFGL+G E L+PA+  ++  ++ LGV S + GMPHRGR
Sbjct: 228 LDDVVKSCGFETFIQLKYGTQLRFGLDGAEALVPAVIALMQEASDLGVTSFVQGMPHRGR 287

Query: 392 LNVLANVCRKPLHQLFTQFAGLEAEDDGS--GDVKYHLG 502
           LN+LANV  KPL  +  +F G    +  +  GD KYHLG
Sbjct: 288 LNLLANVKVKPLTDILAEFEGKTHRNAIARLGDNKYHLG 326


>UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1
           component, sucA; n=1; Candidatus Protochlamydia
           amoebophila UWE25|Rep: Probable 2-oxoglutarate
           dehydrogenase E1 component, sucA - Protochlamydia
           amoebophila (strain UWE25)
          Length = 890

 Score =  115 bits (277), Expect = 6e-25
 Identities = 59/145 (40%), Positives = 87/145 (60%), Gaps = 3/145 (2%)
 Frame = +2

Query: 77  LEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK-MNADQKRLILARLTRSTGFENFL 253
           L + YC+ IG E+  +N  +   WI+  +E     + +  +QK+ +LA L+RS  FE FL
Sbjct: 114 LRKIYCDRIGFEYKHLNDKKMEVWIQDFIEQQFFKQTLTKEQKQHVLACLSRSELFETFL 173

Query: 254 AKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQ 433
             K+  +KRF LEG E LIP +  +I+   + GV+  ++GM HRGRLNVLAN+  K L  
Sbjct: 174 HTKYIGQKRFSLEGAETLIPMLDLLIEAGAEQGVQEFLVGMAHRGRLNVLANILNKSLDT 233

Query: 434 LFTQFAG--LEAEDDGSGDVKYHLG 502
           +F++F    +    +G GDVKYH G
Sbjct: 234 IFSEFGEEYIPTSLEGMGDVKYHKG 258


>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
           component - Anaplasma marginale (strain St. Maries)
          Length = 930

 Score =  115 bits (276), Expect = 7e-25
 Identities = 60/153 (39%), Positives = 96/153 (62%), Gaps = 4/153 (2%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNA-DQKRLILARLTRS 232
           L  IL  L++ YC +IG EFM I S E+ +W+R ++E  N +++ A ++KR  L  L  +
Sbjct: 150 LPSILQALKETYCGSIGYEFMHIPSSEERDWLRDKIE--NTSRVIAPERKRETLRCLQET 207

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
             FE FL  ++   KRF +EG ++L+P ++++I ++     + +++G+ HRGRL+VL  V
Sbjct: 208 ELFEQFLHVRYPGYKRFSVEGGDVLVPLLERIIALAPGFNCKEVVLGLSHRGRLSVLTRV 267

Query: 413 CRKPLHQLFTQFAGLEAEDDG---SGDVKYHLG 502
            RKP   +  +F+G  A  +G   SGDVKYHLG
Sbjct: 268 MRKPYAAVLYEFSGGMAYPEGLSLSGDVKYHLG 300


>UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;
           n=4; Paramecium tetraurelia|Rep: 2-oxoglutarate
           dehydrogenase, putative - Paramecium tetraurelia
          Length = 964

 Score =  115 bits (276), Expect = 7e-25
 Identities = 61/161 (37%), Positives = 92/161 (57%), Gaps = 5/161 (3%)
 Frame = +2

Query: 35  EKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLIL 214
           E ++   +REI +RL Q Y    G+E++ + S EQ +W+ Q M+     K + + +    
Sbjct: 141 EVKEEWTIREIYDRLSQIYTKKYGVEYIHMVSTEQKHWVEQEMDRIAQWKPSKETQTATW 200

Query: 215 ARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRL 394
            RL R   F  FL  ++++ KRFG+EG + LI  ++ ++D   +  VE II+GM HRGRL
Sbjct: 201 QRLARVDLFNEFLKNRFTTSKRFGIEGTDTLIVGLEALVDQCAQNKVEHIIVGMAHRGRL 260

Query: 395 NVLANVCRKPLHQLFTQFAG-----LEAEDDGSGDVKYHLG 502
           + LANV +KPL  +F +F       +E      GDVKYHLG
Sbjct: 261 STLANVFKKPLEIIFAEFQNKYSKEIEESWGNIGDVKYHLG 301


>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
           Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
           Rhodopirellula baltica
          Length = 969

 Score =  114 bits (275), Expect = 1e-24
 Identities = 62/165 (37%), Positives = 94/165 (56%), Gaps = 2/165 (1%)
 Frame = +2

Query: 14  PSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPP-NVTKMN 190
           P  + I E      L  ILN+L+  YC +IG +FM I++    +W+++RME   N   ++
Sbjct: 168 PFDSSILENVSGSTLDVILNKLQSTYCRSIGAQFMHIDNRNIRDWLQRRMETTENRLDLS 227

Query: 191 ADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIM 370
            + +R I  RL  +T FE F+ +K+   K F LEG E LIP +   ++ + +  V+ ++M
Sbjct: 228 HEVQRRIYTRLADATIFEEFVRRKFVGAKTFSLEGAESLIPLIDLALEKAGQHQVKEVVM 287

Query: 371 GMPHRGRLNVLANVCRKPLHQLFTQFAGLEAE-DDGSGDVKYHLG 502
            M HRGRLNV+AN+ +K    +F  F     E   G GDV+YHLG
Sbjct: 288 AMAHRGRLNVMANILKKRAMNIFWSFDDPTPELSRGGGDVRYHLG 332


>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=2; Proteobacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 940

 Score =  114 bits (274), Expect = 1e-24
 Identities = 62/152 (40%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
 Frame = +2

Query: 53  PLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRME-PPNVTKMNADQKRLILARLTR 229
           PL EI   +++ YC+ IG E+M I    +  WI+  +E   +    + + +R IL RLT 
Sbjct: 151 PLEEIFALIKKIYCHTIGAEYMHITETAEKRWIQSYLEGAQDDPGPSVELQRHILERLTA 210

Query: 230 STGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLAN 409
           + G E +L   +  +KRF LEG + LIP +  +I  +   GV  I++GM HRGRLNVL N
Sbjct: 211 AEGLERYLHTNYVGQKRFSLEGGDSLIPLLDNLILYAGSKGVGEIVIGMAHRGRLNVLVN 270

Query: 410 VCRKPLHQLFTQFAGL-EAEDDGSGDVKYHLG 502
              K    LF +F G  E ++  SGDVKYHLG
Sbjct: 271 TLGKLPRDLFMEFEGQHETDNKRSGDVKYHLG 302


>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
           component - Rickettsia felis (Rickettsia azadi)
          Length = 977

 Score =  113 bits (273), Expect = 2e-24
 Identities = 63/152 (41%), Positives = 91/152 (59%), Gaps = 3/152 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           L E++ +L++ Y  +IG+EF  I ++E+ NW+  ++E   VT  +++ K+ IL  L    
Sbjct: 195 LSELVTKLDKTYTGSIGVEFEQIENVEEKNWLYNKLES-EVT-FSSEDKKTILNDLVEVE 252

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
           GFE +L  K+   KRF +EG +  I AM + ID+S   GVE I++GM HRGRLN L  V 
Sbjct: 253 GFEQYLHTKFPGAKRFSVEGGDASIVAMSKAIDLSMNQGVEEIVIGMAHRGRLNTLTKVV 312

Query: 416 RKPLHQLFTQF-AGLEAEDD--GSGDVKYHLG 502
            KP   +   F +G    D+   SGDVKYHLG
Sbjct: 313 GKPYKAVIAGFISGSVFPDELNVSGDVKYHLG 344


>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
           component - Leptospira interrogans
          Length = 920

 Score =  113 bits (273), Expect = 2e-24
 Identities = 57/151 (37%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPN-VTKMNADQKRLILARLTRS 232
           L EI++  E+ YCN IG E  ++ + E+  W++++ME P  +  +    K  +  +L ++
Sbjct: 135 LAEIVDLYEKVYCNTIGAEHFYLVNDEEREWLQKKMESPEFLAPLPRGIKLRLFEKLFQA 194

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
             FE FLAKK+  +KRF LEG E  IP +  +++ +    ++ +++GM HRGRLNVL N+
Sbjct: 195 DYFETFLAKKYVGKKRFSLEGGESFIPLLDTIVEEAGYHQMDGLVIGMAHRGRLNVLVNI 254

Query: 413 CRKPLHQLFTQFAGLEAEDDGS-GDVKYHLG 502
             KP   +F +F     +D+ S  DVKYHLG
Sbjct: 255 IEKPASLIFAEFEEKTDKDNLSYADVKYHLG 285


>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
           decarboxylase - Plesiocystis pacifica SIR-1
          Length = 927

 Score =  112 bits (270), Expect = 4e-24
 Identities = 58/151 (38%), Positives = 88/151 (58%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRS 232
           LREI+ RL   YC ++G+E+  +    Q  W++QRME   N      D++  +L+ L   
Sbjct: 131 LREIIERLRNTYCRHVGVEYWHLYDPAQRAWLQQRMEGCQNEVVPPQDEQVRLLSSLINV 190

Query: 233 TGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANV 412
              ++FL  K+   KRF + G E LIP +  +I+ + +  +  +I GM HRGRLNVL N+
Sbjct: 191 DTVDHFLHSKFLGAKRFSISGAESLIPLLDCLIEGAAEHDIGEVIFGMAHRGRLNVLMNI 250

Query: 413 CRKPLHQLFTQFAGLEAED-DGSGDVKYHLG 502
             K   ++F +F+  +AE   G+GDVKYHLG
Sbjct: 251 LGKAPKEVFEEFSNTDAESYIGAGDVKYHLG 281


>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Staphylococcus aureus
          Length = 932

 Score =  112 bits (269), Expect = 5e-24
 Identities = 57/159 (35%), Positives = 92/159 (57%), Gaps = 12/159 (7%)
 Frame = +2

Query: 62  EILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGF 241
           E + R+E+ Y   I  E+  IN+  +  W+++R+E P    +N ++KR +  +L    GF
Sbjct: 136 EAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGF 195

Query: 242 ENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRK 421
           E +L K +   KRF +EG + L+P +++ I ++ K G+++I +GM HRGRLNVL +V  K
Sbjct: 196 EKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEK 255

Query: 422 PLHQLFTQFAGLE----AEDDGS--------GDVKYHLG 502
           P   + ++F   +      +DGS        GDVKYHLG
Sbjct: 256 PYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLG 294


>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
           2-oxoglutarate dehydrogenase E1 component - Buchnera
           aphidicola subsp. Cinara cedri
          Length = 933

 Score =  111 bits (268), Expect = 7e-24
 Identities = 55/165 (33%), Positives = 93/165 (56%), Gaps = 1/165 (0%)
 Frame = +2

Query: 11  LPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMN 190
           L  + F+  K+     ++I    ++ YC  IG E+M I++ ++  W+++ +E     K+ 
Sbjct: 133 LIKSDFLFFKKNINSFQDIYLFFKKKYCGYIGFEYMHISNTKEKLWLQKNIESKKFEKLF 192

Query: 191 ADQKRL-ILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 367
           + +K+  IL  L +ST +ENF+ KK+   KRF LEGC+ L+P +K++I+      +  I 
Sbjct: 193 SKRKKKNILKNLIKSTVYENFINKKFPGTKRFSLEGCDSLLPMIKEIINFCLNKKITKIF 252

Query: 368 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           +GM HRGRLNV+ N+ +     +F            +GDVKYH+G
Sbjct: 253 LGMAHRGRLNVMHNILKHNTLNMFLNIQDKLCHSHRTGDVKYHIG 297


>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=15; Bacteria|Rep: 2-oxoglutarate
           dehydrogenase, E1 component - Deinococcus radiodurans
          Length = 956

 Score =  111 bits (267), Expect = 9e-24
 Identities = 57/156 (36%), Positives = 93/156 (59%), Gaps = 7/156 (4%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK---MNADQKRLILARLT 226
           LR+++ +L+  YC  IG E+ ++ + E+  W ++R+E         ++ D++R ++ +L 
Sbjct: 143 LRDVIAQLQDTYCGAIGFEYNYLPANERA-WFQERIEKGRGQGRYGLSQDERRRLMQKLN 201

Query: 227 RSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVID-VSTKLGVESIIMGMPHRGRLNVL 403
            + G E +L  ++   KRFGLEG E  IP M ++I     + GV+ +++GM HRGRLN L
Sbjct: 202 AAEGLELYLKNRYPGVKRFGLEGGESFIPLMDRIIQQAGGRYGVKEVVVGMAHRGRLNTL 261

Query: 404 ANVCRKPLHQLFTQFAG---LEAEDDGSGDVKYHLG 502
            N+  KP   LF +F G   L  + D +GDVKYH+G
Sbjct: 262 VNIFGKPSGTLFDEFDGKKKLSDDPDIAGDVKYHMG 297


>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
           , putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
           dehydrogenase E1 component , putative - Babesia bovis
          Length = 891

 Score =  110 bits (265), Expect = 2e-23
 Identities = 60/168 (35%), Positives = 92/168 (54%), Gaps = 4/168 (2%)
 Frame = +2

Query: 11  LPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMN 190
           LPS    G    +  + E ++ L + YC +  +EF+ +   EQ  +I +R+E P     +
Sbjct: 80  LPSGLIPGHMGSSSTVAECIDNLRRTYCGDFAVEFIHLPEEEQRFFI-ERIERPGAMDFS 138

Query: 191 ADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIM 370
            + +      + R+  FE F  K + + KRFG +G E  I A+  + ++S   GV+S+IM
Sbjct: 139 KEDRLNFFRSIARAVTFERFCTKAFPTVKRFGADGIESSILAVDVLSEMSMAFGVDSLIM 198

Query: 371 GMPHRGRLNVLANVCRKPLHQLFTQFAGLE-AEDDGS---GDVKYHLG 502
           GM HRGRLN+L NV  +PL ++F +F G      +GS   GDVKYH G
Sbjct: 199 GMSHRGRLNMLVNVLNRPLEEMFAEFRGKNWYATEGSEYCGDVKYHFG 246


>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Orientia tsutsugamushi Boryong|Rep:
           2-oxoglutarate dehydrogenase, E1 component - Orientia
           tsutsugamushi (strain Boryong) (Rickettsia
           tsutsugamushi)
          Length = 963

 Score =  110 bits (264), Expect = 2e-23
 Identities = 53/151 (35%), Positives = 88/151 (58%), Gaps = 2/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           LR ++++LEQ YC NI +EF  +   ++ +W+  ++E  ++   +   + L+L  L   T
Sbjct: 168 LRTLISQLEQIYCGNIAVEFNHLTDRDEIDWLYDQLEQVSLNLNDNIDRELLLKNLISIT 227

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
           GFE FL  K+   KRF ++G E  I A+   I+ +    ++ +++GM HRGRL  LA V 
Sbjct: 228 GFEEFLHTKFVGAKRFSIQGAEASIAAVIDAIEQAIDYCIKEVVIGMAHRGRLVTLAEVA 287

Query: 416 RKPLHQLFTQFAG-LEAEDDG-SGDVKYHLG 502
           +KP + + ++F   +   D   SGDVKYH+G
Sbjct: 288 KKPHYAIISEFMNEVHINDKNISGDVKYHMG 318


>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Dichelobacter nodosus VCS1703A|Rep:
           2-oxoglutarate dehydrogenase, E1 component -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 917

 Score =  105 bits (252), Expect = 6e-22
 Identities = 55/156 (35%), Positives = 90/156 (57%), Gaps = 2/156 (1%)
 Frame = +2

Query: 41  EKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILA 217
           +K + L +++ RL+  YC++I +E   I    + +W+   +E       ++A Q+  +L 
Sbjct: 131 QKTMRLADLVARLKATYCHHIALETSHIEEQTESDWLYHYLETYAGKYPISAAQQHELLT 190

Query: 218 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 397
           +L  +  FE +L +++  +KRF LEG + LIP + Q+I      G + + + M HRGRLN
Sbjct: 191 QLIAADRFEQYLHQRYVGQKRFSLEGGDALIPLLNQLIMELAHNGAQQLCLAMAHRGRLN 250

Query: 398 VLANVCRKPLHQLFTQFAGLEAEDDG-SGDVKYHLG 502
           VLA+V  KP  ++F +F G  A     +GDVKYHLG
Sbjct: 251 VLAHVLGKPAARIFAEFEGQTASAAPINGDVKYHLG 286


>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
           E1 component - Coxiella burnetii
          Length = 934

 Score =  103 bits (247), Expect = 2e-21
 Identities = 56/157 (35%), Positives = 91/157 (57%), Gaps = 2/157 (1%)
 Frame = +2

Query: 38  KEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEP--PNVTKMNADQKRLI 211
           K KA  L+EI  RL + YC +IG+++  I+   + NW+R  +E   P++ + + + KR I
Sbjct: 144 KPKAT-LKEIYTRLREIYCGSIGVQYSTISDERERNWLRDYVEQRLPSI-EFDKETKRNI 201

Query: 212 LARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGR 391
           L +L  +   E +L  K+  + R+ LEG + LIP + ++   +    +E I++ M HRGR
Sbjct: 202 LQQLVTAESLEKYLDTKYVGQVRYSLEGGDSLIPLLDELTKRARHQKIEEIVICMAHRGR 261

Query: 392 LNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           +NVL N+  +   +LF +F G +     SGDVKYH G
Sbjct: 262 VNVLLNIMGQSAAELFQEFEGKKDYGLMSGDVKYHRG 298


>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
           putative; n=2; Theileria|Rep: 2-oxoglutarate
           dehydrogenase e1 component, putative - Theileria parva
          Length = 1030

 Score =  102 bits (245), Expect = 4e-21
 Identities = 55/168 (32%), Positives = 85/168 (50%), Gaps = 3/168 (1%)
 Frame = +2

Query: 8   KLPSTTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKM 187
           K+P+    G       + E+  +L++ YC NI  EF  I + E+  ++   +E     K 
Sbjct: 158 KIPNLGIGGVFNMTGTVEELAEKLKERYCGNISFEFGHIANSEEVAFLINEIESDEFLKF 217

Query: 188 NADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESII 367
           N +        + ++  FE F AK + + KRFG++G E ++  ++ + +     G+ SI+
Sbjct: 218 NKNDHLKCFKSICKAVKFEQFCAKTFPTLKRFGMDGIESILLLLESIEENGRNFGINSIM 277

Query: 368 MGMPHRGRLNVLANVCRKPLHQLFTQFAGLE---AEDDGSGDVKYHLG 502
           M M HRGRLNVL N   KPL + F +F G          SGDVKYH G
Sbjct: 278 MTMSHRGRLNVLCNFLNKPLQESFAEFRGANWFINSHFRSGDVKYHNG 325


>UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
           Bacillus sp. B14905|Rep: Alpha-ketoglutarate
           decarboxylase - Bacillus sp. B14905
          Length = 670

 Score =  102 bits (244), Expect = 6e-21
 Identities = 54/161 (33%), Positives = 90/161 (55%), Gaps = 13/161 (8%)
 Frame = +2

Query: 59  REILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK-MNADQKRLILARLTRST 235
           ++ ++ L+  Y N +  E+  + + E+ NWI+ ++E  +  + +++D+K+ +L RLTR  
Sbjct: 153 KDAIDYLKAIYTNKVAFEYEHVVATEERNWIQAQIESGSFQQALSSDEKKALLDRLTRVE 212

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
            FE F+ K +  +KRF  EG +  I    ++I  +  L VE + +GM HRGRLNVL ++ 
Sbjct: 213 NFEKFIHKTFVGQKRFSGEGLDTQIVLFDEIIKTAEALSVEKVRIGMAHRGRLNVLTHIL 272

Query: 416 RKPLHQLFTQFA------------GLEAEDDGSGDVKYHLG 502
            KP   +F+ FA             LE     +GDVKYH+G
Sbjct: 273 NKPYDMMFSDFAHVSNDLFMPENGRLEITKGWTGDVKYHMG 313


>UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
           component - Geobacillus kaustophilus
          Length = 950

 Score =  102 bits (244), Expect = 6e-21
 Identities = 54/155 (34%), Positives = 94/155 (60%), Gaps = 13/155 (8%)
 Frame = +2

Query: 77  LEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFL 253
           L + Y + I  EF  +++LE+ NW+ Q++E        A+++R+ +L RLT   GFE F+
Sbjct: 153 LRKIYTDKIAFEFSQVHNLEERNWLIQQIESGAYYPSLANKERVALLRRLTEVEGFEKFI 212

Query: 254 AKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQ 433
            + +  +KRF +EG + ++P + +++  + +  ++++ +GM HRGRLNVLA+V  KP   
Sbjct: 213 HRTYVGQKRFSIEGLDSMVPLLDELVRQAIEHEIDAVNIGMAHRGRLNVLAHVLGKPYEM 272

Query: 434 LFTQFAGLEAED----DGS--------GDVKYHLG 502
           +F +F   E+++    +GS        GDVKYHLG
Sbjct: 273 IFAEFQHAESKNFIPSEGSVAITYGWTGDVKYHLG 307


>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Neorickettsia sennetsu str.
           Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component
           - Neorickettsia sennetsu (strain Miyayama)
          Length = 905

 Score =  101 bits (242), Expect = 1e-20
 Identities = 52/154 (33%), Positives = 81/154 (52%), Gaps = 5/154 (3%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMN--ADQKRLILARLTR 229
           + +I+  +   YC +IG++FM ++   +  W+ +R+E     ++      K  +L  L R
Sbjct: 128 VEQIVCEMHAVYCGHIGVQFMHLSDNSEVTWLEERLEGRPFCRIGFGTSHKLALLDVLIR 187

Query: 230 STGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLAN 409
             G E F+  K+ + KRF +EGC+  + A++ +I+V+   G   +I+GM HRGRLN L N
Sbjct: 188 VNGLEEFVNTKFRAVKRFSVEGCDTALVALESIIEVAANAGCTDVIVGMSHRGRLNSLVN 247

Query: 410 VCRKPLHQLFTQFAG---LEAEDDGSGDVKYHLG 502
              K    LF  F G      E    GDVKYH G
Sbjct: 248 TFGKKYRALFHGFEGKSPFPEECKIHGDVKYHYG 281


>UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1
           component; n=1; Acidobacteria bacterium Ellin345|Rep:
           2-oxoglutarate dehydrogenase, E1 component -
           Acidobacteria bacterium (strain Ellin345)
          Length = 820

 Score =  101 bits (242), Expect = 1e-20
 Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 1/140 (0%)
 Frame = +2

Query: 89  YCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWS 268
           YC  IG+EFM I   E+  WI ++ E         D +R +L  L R+  FE  L  ++ 
Sbjct: 58  YCGTIGVEFMHIADPERRRWIAEKFEGEPGP---VDHRR-VLDALVRADMFEQTLQSRYI 113

Query: 269 SEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF 448
             KR+ LEG   LIP + ++++ + + G E  +M M HRGRLNV+ NV  +P  ++F  F
Sbjct: 114 GTKRYSLEGNTSLIPLLHEILNAAAEHGAEQAVMAMSHRGRLNVIVNVVNRPAAEIFAGF 173

Query: 449 AGLEAEDD-GSGDVKYHLGT 505
             ++     G GDVKYH+G+
Sbjct: 174 EDVDPRSVLGGGDVKYHIGS 193


>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 13 SCAF15000, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 974

 Score =  100 bits (239), Expect = 2e-20
 Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 3/156 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           + E+   LE  YC  + +E   +++LE+  W+  R E       +A+++R +   +  S 
Sbjct: 116 VEEVQAYLEDTYCGRLSVETSQLSTLEEREWLADRFEELKKKSFSAEERRRLAKVMLESQ 175

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
            F++FLA K+++ KR+G EG E ++    ++   S+  GV  I++GMPHRGRLN+L  + 
Sbjct: 176 EFDHFLAAKFATVKRYGGEGAESMMGFFYELFHQSSHSGVTDIVIGMPHRGRLNLLTGLL 235

Query: 416 RKPLHQLFTQFAGLEAEDDGS---GDVKYHLGTYIE 514
           + P   +F +  GL    D S   GDV  HL + +E
Sbjct: 236 KFPPELMFRKMRGLSEFPDSSPAIGDVLSHLTSSVE 271


>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
           putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
           dehydrogenase E1 component, putative - Leishmania major
          Length = 979

 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 50/160 (31%), Positives = 92/160 (57%), Gaps = 9/160 (5%)
 Frame = +2

Query: 50  LPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTK-----MNADQKRLIL 214
           L +R++   L + YC  IG E + +   +   ++R ++E  +        M+ +++  I 
Sbjct: 170 LTIRQLHELLTERYCGRIGFELVHLTDGDAKRFVRSQIELKDGCSALHRPMSREERLRIW 229

Query: 215 ARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRL 394
             +  +  FE+F  +K+S++KRFG +G E ++  ++ +++ S++LGV++I +GM HRGRL
Sbjct: 230 DTVASAVFFEDFFKRKYSTQKRFGCDGAESMVAGLRALLEKSSELGVQAINLGMAHRGRL 289

Query: 395 NVLANVCRKPLHQLFTQFAGLEAED----DGSGDVKYHLG 502
           NVL +V  KP   +  +F G+  ++        DVKYHLG
Sbjct: 290 NVLCHVIGKPFEVILKEFVGVTGQELHPFQIQSDVKYHLG 329


>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
           Dictyostelium discoideum AX4|Rep: Oxoglutarate
           dehydrogenase - Dictyostelium discoideum AX4
          Length = 900

 Score = 99.1 bits (236), Expect = 5e-20
 Identities = 50/151 (33%), Positives = 85/151 (56%), Gaps = 3/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           L ++++ LE AYCN++  +F  I S+E+  W+ ++ E       +  +K  IL  L +S 
Sbjct: 94  LDQVVSFLENAYCNDVTAQFDHIESIEEKAWLYEKFEQLQHQNPSKSEKINILKNLIKSE 153

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
            F+ F+ KK+ + KR+GLEG E ++ +   +   S K  ++++++GMPHRGRLN+L  +C
Sbjct: 154 IFDQFMQKKFPTFKRYGLEGNESMMVSCDSIFRESAKNQLKNVVIGMPHRGRLNLLVQMC 213

Query: 416 RKPLHQLFTQFAGLEAEDD---GSGDVKYHL 499
             P    F +  G     +   G GDV  H+
Sbjct: 214 NYPAKDFFWKVKGNSEFSEGILGVGDVTSHI 244


>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 334

 Score = 97.1 bits (231), Expect = 2e-19
 Identities = 45/92 (48%), Positives = 64/92 (69%)
 Frame = +2

Query: 38  KEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILA 217
           +EK + LREI+   E+ YC + G+E++ I   EQC+W+R R+E     K + D+KR IL 
Sbjct: 214 REK-MTLREIIAACERIYCGSYGVEYIHIPDREQCDWLRARIEVDKPFKYSIDEKRRILD 272

Query: 218 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIP 313
           RL  S+ FE+FLA K+ ++KRFGLEGCE L+P
Sbjct: 273 RLIWSSSFESFLATKYPNDKRFGLEGCETLVP 304


>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
           domain-containing protein 1; n=39; Eumetazoa|Rep:
           Dehydrogenase E1 and transketolase domain-containing
           protein 1 - Homo sapiens (Human)
          Length = 919

 Score = 96.7 bits (230), Expect = 3e-19
 Identities = 52/162 (32%), Positives = 89/162 (54%), Gaps = 3/162 (1%)
 Frame = +2

Query: 38  KEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILA 217
           KE+A  L E+L  L Q YC  I IE   + S ++ +W  +R E         ++++ +  
Sbjct: 110 KEEA-SLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSK 168

Query: 218 RLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLN 397
            +  S  F++FLA K+S+ KR+G EG E ++    +++ +S   G+  +I+GMPHRGRLN
Sbjct: 169 LMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLN 228

Query: 398 VLANVCRKPLHQLFTQFAGLEAEDD---GSGDVKYHLGTYIE 514
           +L  + + P   +F +  GL    +    +GDV  HL + ++
Sbjct: 229 LLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVD 270


>UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component;
           n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1
           component - Chlamydophila abortus
          Length = 908

 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 52/154 (33%), Positives = 84/154 (54%), Gaps = 3/154 (1%)
 Frame = +2

Query: 50  LPLREILNRLEQAYCNNIGIEFMFIN-SLEQCNWIRQRMEPPNVTKMNADQKRLILARLT 226
           +P+R+++  L+  YC +I +E +  +  L++  W     + P   + + ++       + 
Sbjct: 120 VPVRDLIQALKNFYCRSISVETLACSPQLQEYVWKLMESKSP---QRSPEELARSYQDIC 176

Query: 227 RSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLA 406
           ++T FE FL  K++ +KRF LEGCE L+  ++ ++       + S I+GM HRGRLNVL 
Sbjct: 177 KATFFEEFLQVKFTGQKRFSLEGCESLVSMLEHLVRYGVTQNITSYILGMAHRGRLNVLT 236

Query: 407 NVCRKPLHQLFTQFAGLEAED--DGSGDVKYHLG 502
           NV  KP  Q+F +F         D  GDVKYH G
Sbjct: 237 NVLGKPYSQVFMEFEDNPQFRGLDTVGDVKYHKG 270


>UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1;
           Bdellovibrio bacteriovorus|Rep: Oxoglutarate
           dehydrogenase - Bdellovibrio bacteriovorus
          Length = 901

 Score = 95.1 bits (226), Expect = 8e-19
 Identities = 52/157 (33%), Positives = 83/157 (52%), Gaps = 4/157 (2%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           L EI+N L+  YC  + ++     S ++  W+ Q+ E  N  K+    K+  L+ LT++ 
Sbjct: 114 LGEIINHLKATYCGTLSLQAADA-SPKEVQWLTQQFEN-NPAKLALADKKDALSSLTKAE 171

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
             E F+  ++   KRF +EG + ++P M  +++  T   V+ + +GM HRGR+N+L N  
Sbjct: 172 TLEKFVHTRYVGTKRFSVEGADSILPMMDTLVNKGTAQQVQEVFVGMAHRGRVNILVNFF 231

Query: 416 RKPLHQLFTQFAG----LEAEDDGSGDVKYHLGTYIE 514
            KP   +F  F G     E  +D   DVKYHLG   E
Sbjct: 232 GKPEEYVFGDFNGPLELAEPIEDFDNDVKYHLGYVTE 268


>UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
           n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase,
           E1 subunit - Burkholderia phymatum STM815
          Length = 891

 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 55/156 (35%), Positives = 83/156 (53%), Gaps = 4/156 (2%)
 Frame = +2

Query: 47  ALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKR-LILARL 223
           AL + E+  +L++ YC  +G++   +       W+  RME   V      Q+R  +L RL
Sbjct: 114 ALTVGELDQQLKRVYCGGLGLDCSGVRDDSIRRWLFNRMESELVCPQPTPQERDALLRRL 173

Query: 224 TRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVL 403
                +E  +A +    KRF LEGCE L+P +  +I+ S   GV+ I +GMPHRGRLN L
Sbjct: 174 LTVEMWERLVASRHGHAKRFSLEGCESLVPLLDALIESSAIDGVQQIFLGMPHRGRLNAL 233

Query: 404 ANVCRKPLHQLFTQFAGLEAEDDGSG---DVKYHLG 502
            N+   P+ ++    A L+ E D +    D+ YHLG
Sbjct: 234 VNLMDFPVAEM---LACLDHESDIAAMQTDLPYHLG 266


>UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           2-oxoglutarate dehydrogenase, E1 component family
           protein - Tetrahymena thermophila SB210
          Length = 1004

 Score = 91.1 bits (216), Expect = 1e-17
 Identities = 43/145 (29%), Positives = 84/145 (57%)
 Frame = +2

Query: 20  TTFIGEKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQ 199
           +++I    +A  +  +   L++ Y + +G+EF  +N   +  W+    E   +T++ + +
Sbjct: 150 SSYISTLPEAQEVASLEQYLKRVYQDTVGVEFEHVNDPAERTWLYYNFERHQLTELTSFE 209

Query: 200 KRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMP 379
           K  I + L+++   ++FL KK+ + KR+  EG E  I  +K ++  ++++GVE  ++GMP
Sbjct: 210 KVNIHSLLSQTEALDHFLHKKFQTFKRYAGEGAESSIVGLKTILAKASEMGVEDAVIGMP 269

Query: 380 HRGRLNVLANVCRKPLHQLFTQFAG 454
           HRGRLNVL N+   P+  L  + +G
Sbjct: 270 HRGRLNVLCNLLDYPVADLLRKISG 294


>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
           Bilateria|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 911

 Score = 86.2 bits (204), Expect = 4e-16
 Identities = 47/151 (31%), Positives = 76/151 (50%), Gaps = 3/151 (1%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           L ++  +L   YC    IEFM IN+ E+  WI Q  E     ++  ++   I   + +  
Sbjct: 105 LHDLAEQLRHIYCGPTAIEFMHINNWEERQWISQNFENCIAEELRKEELLRIGDLMLKCE 164

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
            F+ FL+ K+ + KR+G EG E +     ++ + + +  VE II+G+ HRGRLN+L  + 
Sbjct: 165 NFDKFLSTKFPTLKRYGAEGAESMFAFFSELFEGAAEKQVEEIIIGIAHRGRLNLLTQLM 224

Query: 416 RKPLHQLFTQFAG---LEAEDDGSGDVKYHL 499
             P   +F +  G        D +GDV  HL
Sbjct: 225 DFPPVHMFRKIKGRAEFPESADAAGDVLSHL 255


>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
           Drosophila melanogaster (Fruit fly)
          Length = 919

 Score = 69.7 bits (163), Expect = 4e-11
 Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 4/144 (2%)
 Frame = +2

Query: 77  LEQAYCN-NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFL 253
           L+  YC  +   EF ++  +E+  W+ +  E  +  ++   ++  I   L +S  ++NF+
Sbjct: 123 LKDIYCGRSTSAEFSYVEDIEEREWLARNFETLDQQQLGKSERCEIAELLIKSQAWDNFM 182

Query: 254 AKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQ 433
           A K+ + KR+G EG E ++    Q++  S +  +E +++ MPHRGR  + A +      +
Sbjct: 183 ALKFPTVKRYGGEGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPLQAALLNMRPAK 242

Query: 434 LFTQFAGLE--AED-DGSGDVKYH 496
           +F +  G    +ED +   DV  H
Sbjct: 243 VFRKLGGASEFSEDIEAMSDVISH 266


>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_10,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 893

 Score = 65.3 bits (152), Expect = 8e-10
 Identities = 42/154 (27%), Positives = 77/154 (50%), Gaps = 4/154 (2%)
 Frame = +2

Query: 56  LREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRST 235
           L E +N+L   Y  ++G+EF  I   E+  W+ +  E     ++    +  I   L +  
Sbjct: 101 LEEYINKL---YAQSVGVEFEQIEDPEEKQWLHENYEKFMNEEITQADRVSIHNLLVQME 157

Query: 236 GFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVC 415
             +++  KK+++ KR+  EG E +I A++ +   + +LGV  ++  M HRGR  +++++ 
Sbjct: 158 AIDHYYHKKFTTFKRYAGEGGEGVIVALRAIYGQAVELGVTDVVQSMAHRGRFPLMSSLL 217

Query: 416 RKPLHQLFTQFAG---LEAE-DDGSGDVKYHLGT 505
             P   +F +  G   L  E   G  DV +HL T
Sbjct: 218 DFPPSDIFRKIMGENDLPQEYTFGVDDVVHHLST 251


>UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;
           Aspergillus|Rep: Contig An06c0020, complete genome -
           Aspergillus niger
          Length = 456

 Score = 40.7 bits (91), Expect = 0.019
 Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
 Frame = +2

Query: 353 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDG-SGDVKYHLG 502
           +E I MG+ HRGR+N L N+  K    +   F   E    G  GDVKYH G
Sbjct: 1   MELIEMGLGHRGRMNALYNIVGKDGPSMLRDFDSKETSAWGMRGDVKYHYG 51


>UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 730

 Score = 39.5 bits (88), Expect = 0.045
 Identities = 21/43 (48%), Positives = 25/43 (58%)
 Frame = +2

Query: 374 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLG 502
           M HRGRLNVL NV  KPL  +  +    +      GDV+YHLG
Sbjct: 1   MAHRGRLNVLHNVFGKPLGAICAEIVD-DRSSFLVGDVRYHLG 42


>UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura
           dioica|Rep: CG1544-PA-like protein - Oikopleura dioica
           (Tunicate)
          Length = 886

 Score = 39.1 bits (87), Expect = 0.059
 Identities = 28/90 (31%), Positives = 46/90 (51%)
 Frame = +2

Query: 134 EQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIP 313
           EQ ++IR  +        +A     IL +L +   F+ FLA ++   KR+GLEG E ++ 
Sbjct: 134 EQQHFIRSELALIEKESSDASHTGYIL-QLAKE--FDEFLALRFPDVKRYGLEGSETIML 190

Query: 314 AMKQVIDVSTKLGVESIIMGMPHRGRLNVL 403
               +++   K     + +GM HRGR N+L
Sbjct: 191 WFDTILNEVDK--DNHVTIGMTHRGRNNLL 218


>UniRef50_A6S3R6 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 977

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 50  LPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKM-NADQKRLILARLT 226
           LPL E+LNRL QA  N++  E M + ++           PP++TK  +     +    L 
Sbjct: 104 LPLTELLNRLAQATHNDLRQEIMKLANM-PIPQSAMNTNPPHITKEDDTSNDNVNKKSLG 162

Query: 227 RSTGFENFLAKKWSSEKRFGLE 292
           ++TG     +K+  SE+ + L+
Sbjct: 163 QATGSTKLESKRRGSEQNYRLK 184


>UniRef50_Q00160 Cluster: Uncharacterized gene 37 protein; n=1;
           Ictalurid herpesvirus 1|Rep: Uncharacterized gene 37
           protein - Ictalurid herpesvirus 1 (IcHV-1) (Channel
           catfish herpesvirus)
          Length = 670

 Score = 33.9 bits (74), Expect = 2.2
 Identities = 22/84 (26%), Positives = 41/84 (48%)
 Frame = +2

Query: 107 IEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFG 286
           I+FMF++SL     +  R+ P  VTK+   +  ++  ++   T  E F A+   +     
Sbjct: 577 IQFMFVDSLNAPGVLMDRLYPSKVTKLTFTELMVLSEKVETVTLPEIFAAQIGLNPSEVR 636

Query: 287 LEGCEILIPAMKQVIDVSTKLGVE 358
           L+  +   P  + V  V+ +LGV+
Sbjct: 637 LKNRDACEPPREIVTGVNHELGVD 660


>UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6;
           Alphaproteobacteria|Rep: Protein-tyrosine-phosphatase -
           Erythrobacter litoralis (strain HTCC2594)
          Length = 157

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
 Frame = +2

Query: 401 LANVCRKPLHQLF----TQFAGLEAEDDGSGDVKYHLG 502
           L N+CR PL +      +  AGL+AE D +G   YH+G
Sbjct: 12  LGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVG 49


>UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza
           sativa|Rep: CAA303711.1 protein - Oryza sativa (Rice)
          Length = 764

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = +3

Query: 414 AVSLCTSCSHSSPVSKLRMMVP 479
           AV+LC +CSH SPVS LR   P
Sbjct: 352 AVTLCRACSHLSPVSPLRSKPP 373


>UniRef50_Q2HW29 Cluster: Putative uncharacterized protein; n=1;
           Medicago truncatula|Rep: Putative uncharacterized
           protein - Medicago truncatula (Barrel medic)
          Length = 244

 Score = 32.7 bits (71), Expect = 5.1
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
 Frame = +2

Query: 20  TTFIGEKEKALPLREILNRLEQAYCNNIGIEFM---FINSLEQCNWIRQRMEPPNVTKMN 190
           ++ +G+K  +LP +   N  E+        EF     + +L Q   + Q +E        
Sbjct: 55  SSVLGKKRYSLPSKVKKNGKEKHNKAAFSNEFQPKPVVGALSQLLLLEQALEQDEGRHSR 114

Query: 191 ADQKRL--ILARLTRSTGFENFLAKKWSSEKR 280
            D++RL  +L  L +  G  NF+  KW + K+
Sbjct: 115 MDKQRLKILLGFLEKKKGLNNFITAKWRASKK 146


>UniRef50_UPI0000546B3D Cluster: PREDICTED: hypothetical protein;
           n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 749

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 13/31 (41%), Positives = 18/31 (58%)
 Frame = +3

Query: 360 PSLWACPIEGASTYSRTCAVSLCTSCSHSSP 452
           P  + CP     TYS TC+ +L  SCS ++P
Sbjct: 246 PCSFTCPESCLKTYSETCSDTLSKSCSFNNP 276


>UniRef50_Q1QBJ3 Cluster: Glycosyl transferase, group 1; n=1;
           Psychrobacter cryohalolentis K5|Rep: Glycosyl
           transferase, group 1 - Psychrobacter cryohalolentis
           (strain K5)
          Length = 373

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 13/51 (25%), Positives = 27/51 (52%)
 Frame = +2

Query: 35  EKEKALPLREILNRLEQAYCNNIGIEFMFINSLEQCNWIRQRMEPPNVTKM 187
           E E+A   +E+  R+++    NIG   + + ++ + NWI    + PN+  +
Sbjct: 71  ETEQATAYKEVAARIDEYVLKNIGTPKLILANIYKVNWIMAYSKLPNIVNV 121


>UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia
           intracellularis PHE/MN1-00|Rep: Hyphotheical protein -
           Lawsonia intracellularis (strain PHE/MN1-00)
          Length = 554

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 15/51 (29%), Positives = 27/51 (52%)
 Frame = +2

Query: 341 TKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKY 493
           T+  + +II   P   R +V++  C++P +     F  L   D+GSGD+ +
Sbjct: 127 TEQAIINIIATAPSGHRKSVISAFCQEPFNIFEKNFNKLRGSDEGSGDLSH 177


>UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 455

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 19/56 (33%), Positives = 28/56 (50%)
 Frame = +2

Query: 326 VIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKY 493
           V+ +STKLG+E+ I     RG+ N+    C  P + +      LE  +DG    KY
Sbjct: 236 VVHLSTKLGLEA-IRAAKARGQKNIYVETC--PQYLMLDDTCYLEQGEDGFAGAKY 288


>UniRef50_A3UUK2 Cluster: Lipase/acylhydrolase family protein; n=2;
           Vibrio|Rep: Lipase/acylhydrolase family protein - Vibrio
           splendidus 12B01
          Length = 278

 Score = 32.3 bits (70), Expect = 6.8
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 17  STTFIGEKEKAL-PLREILNRLEQAYCNNIGIEFMFINSL 133
           ST ++G K + L P  E+LN     YC+  GI F+ +NS+
Sbjct: 200 STLYVGSKLQGLNPSVELLNSKISEYCSQQGIAFLDVNSV 239


>UniRef50_A5KMP2 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus torques ATCC 27756|Rep: Putative
           uncharacterized protein - Ruminococcus torques ATCC
           27756
          Length = 1255

 Score = 31.9 bits (69), Expect = 8.9
 Identities = 17/38 (44%), Positives = 23/38 (60%)
 Frame = +2

Query: 194 DQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEIL 307
           DQ+ LI+A    + G E FL  KWS+ K  G EG +I+
Sbjct: 792 DQRTLIVAAPDDNKGQEKFLGYKWSNRK--GQEGIQII 827


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 550,153,896
Number of Sequences: 1657284
Number of extensions: 11295522
Number of successful extensions: 34075
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 33017
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33972
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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