Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31705
(394 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 96 3e-20
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 96 3e-20
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 96 3e-20
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 96 3e-20
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 96 3e-20
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 96 3e-20
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 96 3e-20
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 85 6e-17
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 85 8e-17
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 85 8e-17
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 85 8e-17
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 83 3e-16
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 83 3e-16
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 81 2e-15
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 81 2e-15
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 79 5e-15
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 77 3e-14
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 77 3e-14
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 77 3e-14
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 77 3e-14
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 77 3e-14
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 77 3e-14
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 77 3e-14
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 77 3e-14
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 77 3e-14
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 74 1e-13
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 74 1e-13
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 74 1e-13
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 74 1e-13
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 74 1e-13
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 74 1e-13
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 74 1e-13
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 74 2e-13
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 74 2e-13
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 74 2e-13
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 74 2e-13
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 74 2e-13
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 74 2e-13
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 58 1e-08
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.007
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 33 0.34
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 33 0.34
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 33 0.34
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 33 0.34
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 33 0.34
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 33 0.34
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 33 0.34
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 33 0.34
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 33 0.34
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 33 0.34
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 33 0.34
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.44
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.44
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 33 0.44
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 33 0.44
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 33 0.44
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 33 0.44
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 33 0.44
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 33 0.44
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 33 0.44
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 33 0.44
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 33 0.44
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 33 0.44
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 33 0.44
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 33 0.44
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 33 0.44
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 1.8
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 30 2.4
BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19 ... 29 4.1
AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein pr... 29 4.1
AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens ... 29 4.1
AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens ... 29 4.1
AB037748-1|BAA92565.2| 1804|Homo sapiens KIAA1327 protein protein. 28 9.5
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 96.3 bits (229), Expect = 3e-20
Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 11/100 (11%)
Frame = +1
Query: 112 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 258
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L NY+DAQYYG I IGTPPQ F VVFDTGS NLWVPS C
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHC 110
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 85.4 bits (202), Expect = 6e-17
Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = +1
Query: 121 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 285
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 286 YGVISIGTPPQSFKVVFDTGSCNLWVPSKKCHY 384
+G I +GTPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHF 111
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 85.0 bits (201), Expect = 8e-17
Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = +1
Query: 121 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 285
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 286 YGVISIGTPPQSFKVVFDTGSCNLWVPSKKCHY 384
+G I +GTPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHF 111
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 85.0 bits (201), Expect = 8e-17
Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = +1
Query: 121 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 285
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 286 YGVISIGTPPQSFKVVFDTGSCNLWVPSKKCHY 384
+G I +GTPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHF 111
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 85.0 bits (201), Expect = 8e-17
Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = +1
Query: 121 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 285
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 286 YGVISIGTPPQSFKVVFDTGSCNLWVPSKKCHY 384
+G I +GTPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHF 111
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 83.0 bits (196), Expect = 3e-16
Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 5/86 (5%)
Frame = +1
Query: 142 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 306
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 307 TPPQSFKVVFDTGSCNLWVPSKKCHY 384
TPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHF 107
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 83.0 bits (196), Expect = 3e-16
Identities = 41/86 (47%), Positives = 54/86 (62%), Gaps = 5/86 (5%)
Frame = +1
Query: 142 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 306
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 307 TPPQSFKVVFDTGSCNLWVPSKKCHY 384
TPPQ+F V FDTGS NLWVPS++CH+
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHF 111
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 80.6 bits (190), Expect = 2e-15
Identities = 47/104 (45%), Positives = 57/104 (54%), Gaps = 12/104 (11%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 252
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 253 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
+PL NYLD +Y+G I IGTP Q F VVFDTGS NLWVPS C
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC 107
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 80.6 bits (190), Expect = 2e-15
Identities = 47/104 (45%), Positives = 57/104 (54%), Gaps = 12/104 (11%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 252
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 253 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
+PL NYLD +Y+G I IGTP Q F VVFDTGS NLWVPS C
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC 107
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 79.0 bits (186), Expect = 5e-15
Identities = 46/104 (44%), Positives = 57/104 (54%), Gaps = 12/104 (11%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 252
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 253 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
+PL NYLD +Y+G I IGTP Q F V+FDTGS NLWVPS C
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC 107
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-14
Identities = 31/40 (77%), Positives = 35/40 (87%)
Frame = +1
Query: 259 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
L+NY+D QYYG I IGTPPQ+FKVVFDTGS N+WVPS KC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKC 117
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 74.1 bits (174), Expect = 1e-13
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)
Frame = +1
Query: 103 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 252
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 253 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGS NLWVPS C
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC 109
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 101
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 73.7 bits (173), Expect = 2e-13
Identities = 43/89 (48%), Positives = 54/89 (60%), Gaps = 9/89 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNLWVPSKKC 378
ISIGTPPQ+F V+FDTGS NLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 58.0 bits (134), Expect = 1e-08
Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 9/82 (10%)
Frame = +1
Query: 139 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 291
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 292 VISIGTPPQSFKVVFDTGSCNL 357
ISIGTPPQ+F V+FDTGS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.007
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +1
Query: 130 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 282
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 283 YYGVISIGTP 312
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAV 39
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.1 bits (72), Expect = 0.34
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY + IGTPPQ +++ DTGS N V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAV 88
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 32.7 bits (71), Expect = 0.44
Identities = 12/27 (44%), Positives = 19/27 (70%)
Frame = +1
Query: 283 YYGVISIGTPPQSFKVVFDTGSCNLWV 363
YY +++G+PPQ+ ++ DTGS N V
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAV 132
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 1.8
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -2
Query: 348 GSGVEYHLERLRRRADTDHSVVLSIK 271
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 30.3 bits (65), Expect = 2.4
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 301 IGTPPQSFKVVFDTGSCNLWV 363
IGTPPQ +++ DTGS N V
Sbjct: 3 IGTPPQKLQILVDTGSSNFAV 23
>BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19
protein.
Length = 458
Score = 29.5 bits (63), Expect = 4.1
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 280 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 164
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 137 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 175
>AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein
protein.
Length = 339
Score = 29.5 bits (63), Expect = 4.1
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 280 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 164
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 18 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 56
>AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 4.1
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 280 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 164
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ31005 fis, clone HLUNG2000068, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 4.1
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 280 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 164
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AB037748-1|BAA92565.2| 1804|Homo sapiens KIAA1327 protein protein.
Length = 1804
Score = 28.3 bits (60), Expect = 9.5
Identities = 11/29 (37%), Positives = 18/29 (62%)
Frame = -1
Query: 280 EHQDNLTMVRVKGQSHRILISTAPVQCQP 194
+ +D LT+ RV+ S +IST+ +C P
Sbjct: 1064 QDEDRLTITRVEDLSDAAIISTSTAECMP 1092
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,215,127
Number of Sequences: 237096
Number of extensions: 1296447
Number of successful extensions: 2369
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 2314
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2358
length of database: 76,859,062
effective HSP length: 82
effective length of database: 57,417,190
effective search space used: 2756025120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -