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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= epV31676
         (516 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC038233-1|AAH38233.1|  771|Homo sapiens pleckstrin and Sec7 dom...    31   3.2  
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.          30   4.2  
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.          30   4.2  
U48436-1|AAC82513.1| 1311|Homo sapiens fragile X mental retardat...    29   7.3  
BC132683-1|AAI32684.1| 1301|Homo sapiens AFF2 protein protein.         29   7.3  
BC075045-1|AAH75045.1|  534|Homo sapiens PSD3 protein protein.         29   7.3  
BC075044-1|AAH75044.1|  533|Homo sapiens PSD3 protein protein.         29   7.3  
AJ001550-1|CAA04822.1| 1272|Homo sapiens FMR2 protein protein.         29   7.3  
AF519767-1|AAM74203.1|  534|Homo sapiens ADP-ribosylation factor...    29   7.3  
AF243495-1|AAF61269.2|  534|Homo sapiens hepatocellular carcinom...    29   7.3  
AF012624-1|AAB71534.1| 1311|Homo sapiens familial mental retarda...    29   7.3  
AB208940-1|BAD92177.1|  861|Homo sapiens Hypothetical protein DK...    29   7.3  
AB102644-1|BAC81113.1| 1272|Homo sapiens FMR2 protein.                 29   7.3  
AB023159-1|BAA76786.2|  537|Homo sapiens KIAA0942 protein protein.     29   7.3  
BC142950-1|AAI42951.1|  736|Homo sapiens endothelin converting e...    29   9.7  
AY359003-1|AAQ89362.1|  736|Homo sapiens ECE2 protein.                 29   9.7  
AF521189-1|AAM77664.1|  811|Homo sapiens endothelin-converting e...    29   9.7  
AF428264-1|AAL30387.1|  736|Homo sapiens endothelin converting e...    29   9.7  
AF428263-1|AAL30386.1|  787|Homo sapiens endothelin converting e...    29   9.7  
AF192531-1|AAG28399.1|  765|Homo sapiens endothelin-converting e...    29   9.7  
AB011176-1|BAA25530.2|  773|Homo sapiens KIAA0604 protein protein.     29   9.7  

>BC038233-1|AAH38233.1|  771|Homo sapiens pleckstrin and Sec7 domain
           containing 2 protein.
          Length = 771

 Score = 30.7 bits (66), Expect = 3.2
 Identities = 17/43 (39%), Positives = 24/43 (55%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           KTH DM G+  TP  + R W+ F   LKG+     ++ YRP +
Sbjct: 522 KTHADMDGKR-TPRGR-RGWKKFYAVLKGTILYLQKDEYRPDK 562


>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
          Length = 2767

 Score = 30.3 bits (65), Expect = 4.2
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 128 GRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIAA 307
           G++ TP+K      S+  +  G+  +  +  Y   ++ VFP +LS YP   S+ D P+AA
Sbjct: 794 GQDLTPAKLLVKIMSYREAASGNFSLFIQSLYEAGQQDVFP-VLSQYP---SLQDVPLAA 849

Query: 308 AE 313
            E
Sbjct: 850 LE 851


>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
          Length = 2768

 Score = 30.3 bits (65), Expect = 4.2
 Identities = 20/62 (32%), Positives = 33/62 (53%)
 Frame = +2

Query: 128 GRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIAA 307
           G++ TP+K      S+  +  G+  +  +  Y   ++ VFP +LS YP   S+ D P+AA
Sbjct: 794 GQDLTPAKLLVKIMSYREAASGNFSLFIQSLYEAGQQDVFP-VLSQYP---SLQDVPLAA 849

Query: 308 AE 313
            E
Sbjct: 850 LE 851


>U48436-1|AAC82513.1| 1311|Homo sapiens fragile X mental retardation
            protein FMR2p protein.
          Length = 1311

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 19/74 (25%), Positives = 33/74 (44%)
 Frame = +3

Query: 201  TSEPRKGTGQHAAAFFPNSCRPTLTPSRFTTTLSLPLRGLRYPATVTCLSIARSTATPRA 380
            +++P++  G+  A F   S     TP + ++            ATVT  +I  +T T  A
Sbjct: 951  STKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATA 1010

Query: 381  LSMPTTTLALSIIT 422
             +  TTT   + I+
Sbjct: 1011 TATATTTTTTTTIS 1024


>BC132683-1|AAI32684.1| 1301|Homo sapiens AFF2 protein protein.
          Length = 1301

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 19/74 (25%), Positives = 33/74 (44%)
 Frame = +3

Query: 201  TSEPRKGTGQHAAAFFPNSCRPTLTPSRFTTTLSLPLRGLRYPATVTCLSIARSTATPRA 380
            +++P++  G+  A F   S     TP + ++            ATVT  +I  +T T  A
Sbjct: 941  STKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATA 1000

Query: 381  LSMPTTTLALSIIT 422
             +  TTT   + I+
Sbjct: 1001 TATATTTTTTTTIS 1014


>BC075045-1|AAH75045.1|  534|Homo sapiens PSD3 protein protein.
          Length = 534

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           K H DM G+ +TP  K R W++F   LKG+     ++ Y+P +
Sbjct: 281 KIHADMDGK-KTPRGK-RGWKTFYAVLKGTVLYLQKDEYKPEK 321


>BC075044-1|AAH75044.1|  533|Homo sapiens PSD3 protein protein.
          Length = 533

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           K H DM G+ +TP  K R W++F   LKG+     ++ Y+P +
Sbjct: 280 KIHADMDGK-KTPRGK-RGWKTFYAVLKGTVLYLQKDEYKPEK 320


>AJ001550-1|CAA04822.1| 1272|Homo sapiens FMR2 protein protein.
          Length = 1272

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 19/74 (25%), Positives = 33/74 (44%)
 Frame = +3

Query: 201  TSEPRKGTGQHAAAFFPNSCRPTLTPSRFTTTLSLPLRGLRYPATVTCLSIARSTATPRA 380
            +++P++  G+  A F   S     TP + ++            ATVT  +I  +T T  A
Sbjct: 912  STKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATA 971

Query: 381  LSMPTTTLALSIIT 422
             +  TTT   + I+
Sbjct: 972  TATATTTTTTTTIS 985


>AF519767-1|AAM74203.1|  534|Homo sapiens ADP-ribosylation factor
           guanine nucleotide factor 6 protein.
          Length = 534

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           K H DM G+ +TP  K R W++F   LKG+     ++ Y+P +
Sbjct: 281 KIHADMDGK-KTPRGK-RGWKTFYAVLKGTVLYLQKDEYKPEK 321


>AF243495-1|AAF61269.2|  534|Homo sapiens hepatocellular
           carcinoma-associated antigen 67 protein.
          Length = 534

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           K H DM G+ +TP  K R W++F   LKG+     ++ Y+P +
Sbjct: 281 KIHADMDGK-KTPRGK-RGWKTFYAVLKGTVLYLQKDEYKPEK 321


>AF012624-1|AAB71534.1| 1311|Homo sapiens familial mental retardation
            protein 2 protein.
          Length = 1311

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 19/74 (25%), Positives = 33/74 (44%)
 Frame = +3

Query: 201  TSEPRKGTGQHAAAFFPNSCRPTLTPSRFTTTLSLPLRGLRYPATVTCLSIARSTATPRA 380
            +++P++  G+  A F   S     TP + ++            ATVT  +I  +T T  A
Sbjct: 951  STKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATA 1010

Query: 381  LSMPTTTLALSIIT 422
             +  TTT   + I+
Sbjct: 1011 TATATTTTTTTTIS 1024


>AB208940-1|BAD92177.1|  861|Homo sapiens Hypothetical protein
           DKFZp434B216 variant protein.
          Length = 861

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 15/39 (38%), Positives = 21/39 (53%)
 Frame = +1

Query: 349 PSRDLRLLPAPYLCPQLPSLSRLLQANPKSLRGSXNLKT 465
           P+  + L+P P L     +LS  L A PK++    NLKT
Sbjct: 296 PNESVLLMPLPILLHVQETLSTELSAAPKNVTSMINLKT 334


>AB102644-1|BAC81113.1| 1272|Homo sapiens FMR2 protein.
          Length = 1272

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 19/74 (25%), Positives = 33/74 (44%)
 Frame = +3

Query: 201  TSEPRKGTGQHAAAFFPNSCRPTLTPSRFTTTLSLPLRGLRYPATVTCLSIARSTATPRA 380
            +++P++  G+  A F   S     TP + ++            ATVT  +I  +T T  A
Sbjct: 912  STKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATA 971

Query: 381  LSMPTTTLALSIIT 422
             +  TTT   + I+
Sbjct: 972  TATATTTTTTTTIS 985


>AB023159-1|BAA76786.2|  537|Homo sapiens KIAA0942 protein protein.
          Length = 537

 Score = 29.5 bits (63), Expect = 7.3
 Identities = 16/43 (37%), Positives = 25/43 (58%)
 Frame = +2

Query: 107 KTHLDMIGRNETPSKKARFWQSFVRSLKGSEDIRAEERYRPTR 235
           K H DM G+ +TP  K R W++F   LKG+     ++ Y+P +
Sbjct: 284 KIHADMDGK-KTPRGK-RGWKTFYAVLKGTVLYLQKDEYKPEK 324


>BC142950-1|AAI42951.1|  736|Homo sapiens endothelin converting
           enzyme 2 protein.
          Length = 736

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 475 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 532

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 533 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 564


>AY359003-1|AAQ89362.1|  736|Homo sapiens ECE2 protein.
          Length = 736

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 475 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 532

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 533 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 564


>AF521189-1|AAM77664.1|  811|Homo sapiens endothelin-converting
           enzyme-2C protein.
          Length = 811

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 550 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 607

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 608 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 639


>AF428264-1|AAL30387.1|  736|Homo sapiens endothelin converting
           enzyme-2B protein.
          Length = 736

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 475 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 532

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 533 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 564


>AF428263-1|AAL30386.1|  787|Homo sapiens endothelin converting
           enzyme-2A protein.
          Length = 787

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 526 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 583

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 584 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 615


>AF192531-1|AAG28399.1|  765|Homo sapiens endothelin-converting
           enzyme 2B protein.
          Length = 765

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 504 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 561

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 562 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 593


>AB011176-1|BAA25530.2|  773|Homo sapiens KIAA0604 protein protein.
          Length = 773

 Score = 29.1 bits (62), Expect = 9.7
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
 Frame = +2

Query: 173 FVRSLKGSEDIRAEERYRPTRRSVFPELLSTYPYSKSIYDDPIA--------AAERITVP 328
           F+   K  +D+   + Y  +  S F  +L+ Y +S  +  D +         +    TV 
Sbjct: 512 FILEPKELDDVY--DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVN 569

Query: 329 GYRYLPVHREIY---GYSPRPIYAHNYPRSLDY 418
            Y YLP   EI    G    P YA N+P++L++
Sbjct: 570 AY-YLPTKNEIVFPAGILQAPFYARNHPKALNF 601


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,130,662
Number of Sequences: 237096
Number of extensions: 1469493
Number of successful extensions: 7885
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 7687
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7871
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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