Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31595
(516 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 190 1e-47
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 190 1e-47
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 174 1e-42
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 164 9e-40
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 155 7e-37
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 150 2e-35
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 146 2e-34
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 145 5e-34
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 142 3e-33
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 140 1e-32
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 140 2e-32
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 140 2e-32
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 139 3e-32
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 139 3e-32
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 138 5e-32
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 138 7e-32
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 138 7e-32
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 137 1e-31
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 137 2e-31
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 137 2e-31
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 136 3e-31
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 135 6e-31
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 133 3e-30
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 131 8e-30
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 131 1e-29
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 130 1e-29
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 130 2e-29
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 130 2e-29
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 130 2e-29
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 129 4e-29
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 128 7e-29
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 128 1e-28
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 127 1e-28
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 126 2e-28
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 126 3e-28
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 126 3e-28
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 125 7e-28
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 124 9e-28
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 123 2e-27
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 123 3e-27
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 122 4e-27
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 122 4e-27
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 122 5e-27
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 122 5e-27
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 120 1e-26
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 120 2e-26
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 120 2e-26
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 118 6e-26
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 118 6e-26
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 118 8e-26
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 117 1e-25
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 116 4e-25
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 113 2e-24
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 112 5e-24
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 110 2e-23
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 109 3e-23
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 79 2e-22
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 105 6e-22
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 104 1e-21
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 2e-21
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 102 4e-21
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 102 4e-21
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 102 6e-21
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 101 1e-20
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 2e-20
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 100 4e-20
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 9e-20
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 98 1e-19
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 1e-19
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 98 1e-19
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 98 1e-19
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 97 2e-19
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 96 4e-19
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 96 5e-19
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 96 5e-19
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 94 1e-18
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 1e-18
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 94 2e-18
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 94 2e-18
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 93 3e-18
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 93 5e-18
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 5e-18
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 91 1e-17
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 2e-17
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 2e-17
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 90 3e-17
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 3e-17
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 90 3e-17
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 89 6e-17
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 6e-17
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 89 7e-17
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 89 7e-17
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 88 1e-16
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 88 1e-16
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 88 1e-16
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 88 1e-16
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 2e-16
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 87 2e-16
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 86 4e-16
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 5e-16
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 7e-16
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 7e-16
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 7e-16
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 85 7e-16
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 9e-16
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 84 2e-15
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 84 2e-15
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 2e-15
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 3e-15
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 83 3e-15
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 4e-15
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 4e-15
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 83 5e-15
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 5e-15
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 82 8e-15
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 82 8e-15
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 1e-14
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 81 1e-14
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 1e-14
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 1e-14
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 81 1e-14
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 1e-14
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 81 1e-14
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 1e-14
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 81 2e-14
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 80 3e-14
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 3e-14
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 80 3e-14
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 80 3e-14
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 3e-14
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 80 3e-14
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 79 4e-14
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 79 4e-14
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 4e-14
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 4e-14
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 79 6e-14
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 6e-14
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 79 6e-14
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 79 8e-14
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 78 1e-13
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 78 1e-13
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 1e-13
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 77 2e-13
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 77 3e-13
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 76 4e-13
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 4e-13
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 76 4e-13
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 76 6e-13
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 6e-13
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 75 7e-13
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 7e-13
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 74 2e-12
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 74 2e-12
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 74 2e-12
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 74 2e-12
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 2e-12
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 3e-12
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 73 3e-12
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 73 4e-12
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 4e-12
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 73 4e-12
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 5e-12
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 5e-12
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 7e-12
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 72 7e-12
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 7e-12
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 72 9e-12
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 9e-12
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 72 9e-12
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 72 9e-12
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 72 9e-12
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 71 1e-11
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 71 1e-11
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 71 2e-11
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 71 2e-11
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 71 2e-11
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 71 2e-11
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 70 3e-11
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-11
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 70 3e-11
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 70 3e-11
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 70 3e-11
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 70 3e-11
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 70 3e-11
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 70 3e-11
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 70 4e-11
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 70 4e-11
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 69 5e-11
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 5e-11
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 5e-11
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 69 5e-11
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 69 5e-11
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 69 5e-11
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 69 5e-11
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 69 6e-11
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 6e-11
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 69 6e-11
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 69 6e-11
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 6e-11
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 69 6e-11
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 69 6e-11
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 6e-11
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 69 8e-11
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 69 8e-11
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 69 8e-11
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 69 8e-11
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 68 1e-10
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 1e-10
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 68 1e-10
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 68 1e-10
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 68 1e-10
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 68 1e-10
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 1e-10
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 1e-10
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 68 1e-10
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 67 2e-10
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 67 2e-10
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 2e-10
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 2e-10
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 67 2e-10
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 67 3e-10
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 67 3e-10
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 67 3e-10
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 67 3e-10
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 3e-10
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 66 3e-10
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 3e-10
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 66 3e-10
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 66 4e-10
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 4e-10
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 4e-10
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 66 6e-10
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 66 6e-10
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 66 6e-10
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 66 6e-10
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 66 6e-10
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 66 6e-10
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 65 8e-10
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 8e-10
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 65 8e-10
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 65 1e-09
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 65 1e-09
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 65 1e-09
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 65 1e-09
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 65 1e-09
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 65 1e-09
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 65 1e-09
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 64 1e-09
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 1e-09
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 64 1e-09
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-09
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 64 1e-09
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 1e-09
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 64 1e-09
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 64 2e-09
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 64 2e-09
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 64 2e-09
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 64 2e-09
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 64 2e-09
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 2e-09
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 3e-09
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 63 3e-09
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 4e-09
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 63 4e-09
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 63 4e-09
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 4e-09
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 63 4e-09
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 4e-09
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 4e-09
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 6e-09
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 62 6e-09
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 6e-09
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 6e-09
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 62 6e-09
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 62 7e-09
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 62 7e-09
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 62 7e-09
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 62 1e-08
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 62 1e-08
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 62 1e-08
UniRef50_Q5QUE2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 62 1e-08
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 1e-08
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 61 1e-08
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 1e-08
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 61 2e-08
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 61 2e-08
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 60 2e-08
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 60 2e-08
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 60 2e-08
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 60 2e-08
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 60 2e-08
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 2e-08
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 3e-08
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 60 3e-08
UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 60 3e-08
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 60 3e-08
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 60 4e-08
UniRef50_Q82ZC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 4e-08
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 60 4e-08
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 60 4e-08
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 60 4e-08
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 59 5e-08
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 59 5e-08
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 59 5e-08
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 5e-08
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 59 5e-08
UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular ... 59 7e-08
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 59 7e-08
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 7e-08
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 7e-08
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 59 7e-08
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 9e-08
UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 58 9e-08
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 58 1e-07
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 1e-07
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 58 1e-07
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 58 1e-07
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 58 2e-07
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 58 2e-07
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 58 2e-07
UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 58 2e-07
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 2e-07
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 2e-07
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 57 3e-07
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 57 3e-07
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 57 3e-07
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 57 3e-07
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 3e-07
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 57 3e-07
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 4e-07
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 4e-07
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 56 4e-07
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 4e-07
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 56 4e-07
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 56 5e-07
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 56 5e-07
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 5e-07
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 5e-07
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 6e-07
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 56 6e-07
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 56 6e-07
UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 6e-07
UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase; ... 56 6e-07
UniRef50_UPI00015B4C72 Cluster: PREDICTED: similar to ENSANGP000... 55 8e-07
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 8e-07
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 8e-07
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 55 8e-07
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 8e-07
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 55 8e-07
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 55 8e-07
UniRef50_Q5PCV8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 55 8e-07
UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase; ... 55 1e-06
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 55 1e-06
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 55 1e-06
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 54 1e-06
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 1e-06
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 1e-06
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 54 1e-06
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 1e-06
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 54 1e-06
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 54 1e-06
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 1e-06
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 54 1e-06
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 54 2e-06
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 2e-06
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 54 3e-06
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 54 3e-06
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 54 3e-06
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 54 3e-06
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 54 3e-06
UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase; ... 54 3e-06
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 54 3e-06
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 54 3e-06
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 53 3e-06
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 53 3e-06
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 53 3e-06
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 3e-06
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 3e-06
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 53 3e-06
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 53 3e-06
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 53 3e-06
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 53 3e-06
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 53 4e-06
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 4e-06
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 53 4e-06
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 53 4e-06
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 52 6e-06
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 6e-06
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 6e-06
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 6e-06
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 52 6e-06
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 52 8e-06
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 52 8e-06
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 8e-06
UniRef50_A6Q6K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 8e-06
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 52 8e-06
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 52 8e-06
UniRef50_Q8H423 Cluster: Putative phosphoglycerate dehydrogenase... 52 8e-06
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 52 8e-06
UniRef50_Q0CK41 Cluster: Putative uncharacterized protein; n=5; ... 52 8e-06
UniRef50_A5CWD1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 52 8e-06
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 52 1e-05
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 52 1e-05
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 52 1e-05
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase; ... 52 1e-05
UniRef50_A7PQ72 Cluster: Chromosome chr18 scaffold_24, whole gen... 52 1e-05
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 51 1e-05
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 51 1e-05
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 51 1e-05
UniRef50_A0IKR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 1e-05
UniRef50_Q65DI8 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_Q11GX7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 2e-05
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 51 2e-05
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 51 2e-05
UniRef50_A4SNU1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 51 2e-05
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 50 2e-05
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 50 3e-05
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 50 3e-05
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 50 3e-05
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_Q5AUK0 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_A2R1X3 Cluster: Remark: D(--)-Mandelate dehydrogenase; ... 50 4e-05
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 50 4e-05
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 49 6e-05
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 49 6e-05
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 6e-05
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 49 6e-05
UniRef50_A2D764 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 6e-05
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 49 6e-05
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 49 6e-05
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 7e-05
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 7e-05
UniRef50_A0YAX4 Cluster: Phosphoglycerate dehydrogenase and rela... 49 7e-05
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 49 7e-05
UniRef50_Q8A2E4 Cluster: Erythronate-4-phosphate dehydrogenase; ... 49 7e-05
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 49 7e-05
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 48 1e-04
UniRef50_Q2B326 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 1e-04
UniRef50_A6DPW5 Cluster: 2-hydroxyacid-family dehydrogenase; n=2... 48 1e-04
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 1e-04
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 1e-04
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 48 1e-04
UniRef50_Q1YTV2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 1e-04
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 48 1e-04
UniRef50_A5FIN4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 1e-04
UniRef50_Q8D2P6 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 1e-04
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 48 1e-04
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 48 2e-04
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 48 2e-04
UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1; Rhi... 48 2e-04
UniRef50_A7CWK1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A6UHC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A4B0Y8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 48 2e-04
UniRef50_A1W7E2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 48 2e-04
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 47 2e-04
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 47 2e-04
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 47 2e-04
UniRef50_A4AK07 Cluster: Glycerate dehydrogenase; n=1; marine ac... 47 2e-04
UniRef50_Q9I3W9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 47 2e-04
UniRef50_Q7VRU9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 47 2e-04
UniRef50_Q6F943 Cluster: Erythronate-4-phosphate dehydrogenase; ... 47 2e-04
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 47 3e-04
UniRef50_A7LVV2 Cluster: Putative uncharacterized protein; n=1; ... 47 3e-04
UniRef50_A6PLZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 3e-04
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 190 bits (464), Expect = 1e-47
Identities = 86/158 (54%), Positives = 118/158 (74%)
Frame = +2
Query: 41 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 220
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 221 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 400
+V+ A LK+VGRAG GVDNID+ +A + G+ V+N PG N++SACELTC ++ LAR+V
Sbjct: 61 DVIAASPNLKLVGRAGTGVDNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNV 120
Query: 401 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
V A ++K GRWDR LY G EL+GK L ++G GR+GRE
Sbjct: 121 VQAGQSMKEGRWDRKLYAGRELSGKALGVVGFGRIGRE 158
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 190 bits (464), Expect = 1e-47
Identities = 92/158 (58%), Positives = 119/158 (75%)
Frame = +2
Query: 41 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 220
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 221 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 400
+V L+VVGRAG GVDNID+++A +KGV V+N PG N++SACELTC L+ LAR+V
Sbjct: 61 DVFACCPNLRVVGRAGTGVDNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNV 120
Query: 401 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
A +LK GRWDR LY+G EL+GKTLA+LG+GR+GRE
Sbjct: 121 TQAVQSLKDGRWDRKLYSGFELSGKTLAVLGMGRIGRE 158
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 174 bits (423), Expect = 1e-42
Identities = 82/156 (52%), Positives = 110/156 (70%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 226
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 227 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 406
+ AG LK++GRAG GVDNID +A GV V+N PG N LSA E TC L+ LARH+
Sbjct: 64 IKAGKNLKIIGRAGTGVDNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQ 123
Query: 407 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
AS + K G+W+R + G+EL GKTLAI+GLGR+GRE
Sbjct: 124 ASASTKEGKWERKQFMGNELFGKTLAIIGLGRIGRE 159
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 164 bits (399), Expect = 9e-40
Identities = 75/155 (48%), Positives = 113/155 (72%)
Frame = +2
Query: 50 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
+A KL+VVGRAG GVDN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A
Sbjct: 65 NAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQA 124
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ ++K G+W+R + G+EL GKTL ILGLGR+GRE
Sbjct: 125 TASMKDGKWERKKFMGTELNGKTLGILGLGRIGRE 159
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 155 bits (375), Expect = 7e-37
Identities = 73/155 (47%), Positives = 105/155 (67%)
Frame = +2
Query: 50 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
+L+++GRAG GVDNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A
Sbjct: 71 AKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQA 130
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
LK G W++ LY G EL GKTL+++GLGRVGRE
Sbjct: 131 MADLKQGNWNKHLYAGIELEGKTLSLIGLGRVGRE 165
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 150 bits (363), Expect = 2e-35
Identities = 66/152 (43%), Positives = 111/152 (73%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
LK++GRAG G+DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +
Sbjct: 63 KNLKIIGRAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANAS 122
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
LK+G+W+R+ + G E+ KTL I+GLGR+G E
Sbjct: 123 LKSGKWERSKFMGVEVMNKTLGIIGLGRIGGE 154
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 147 bits (355), Expect = 2e-34
Identities = 71/151 (47%), Positives = 104/151 (68%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V++
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLKV+GRAG GVDNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +L
Sbjct: 63 KLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASL 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
K G WDR + G EL GKTL ++GLGR+G++
Sbjct: 123 KRGEWDRKRFKGIELYGKTLGVIGLGRIGQQ 153
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 145 bits (352), Expect = 5e-34
Identities = 65/151 (43%), Positives = 99/151 (65%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAK 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LK++GRAG GVDNID+++A ++G+ V+NAPG N +S E LML AR + A ++
Sbjct: 63 NLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSV 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
K G+W+R + G EL GKT ++GLGRVG E
Sbjct: 123 KEGKWERKKFMGIELRGKTAGVIGLGRVGFE 153
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 142 bits (345), Expect = 3e-33
Identities = 73/154 (47%), Positives = 100/154 (64%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 232
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
AG KL+V+GRAG GVDNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+
Sbjct: 60 AGKKLQVIGRAGVGVDNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRAN 119
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+LK+G+W R + GSEL GKTL I+GLG +G E
Sbjct: 120 ASLKSGQWKRNEFVGSELKGKTLGIVGLGNIGSE 153
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 140 bits (340), Expect = 1e-32
Identities = 72/151 (47%), Positives = 99/151 (65%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++DA
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDASE 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LKV+ RAG GVDN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +L
Sbjct: 63 NLKVIARAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASL 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
K G WDR + G E+ KTL I+GLGR+G++
Sbjct: 123 KKGEWDRKSFKGMEVYAKTLGIVGLGRIGQQ 153
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 140 bits (339), Expect = 2e-32
Identities = 70/126 (55%), Positives = 90/126 (71%), Gaps = 1/126 (0%)
Frame = +2
Query: 140 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
K++ EELL IP +DAL+ RS T+VT EVL G +LKVVGRAG GVDNIDV +A ++GV
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVLARGTRLKVVGRAGVGVDNIDVAAATERGVV 86
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGL 496
V+N PGAN S E L++ +AR++ A AL + GRWDR + G+EL GKTL I+GL
Sbjct: 87 VVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFVGTELHGKTLGIIGL 146
Query: 497 GRVGRE 514
GR+G E
Sbjct: 147 GRIGSE 152
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 140 bits (338), Expect = 2e-32
Identities = 63/127 (49%), Positives = 95/127 (74%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
+ + K L+ +P +DAL+VRSAT+VT EVL AG +L+VVGRAG GVDNID+++A ++G
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLRVVGRAGTGVDNIDLEAATRQG 86
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILG 493
+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+R + G E+ KTL ++G
Sbjct: 87 IMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMGFEVRNKTLGLVG 146
Query: 494 LGRVGRE 514
LGR+G E
Sbjct: 147 LGRIGAE 153
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 139 bits (337), Expect = 3e-32
Identities = 67/151 (44%), Positives = 96/151 (63%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++AG
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAGK 65
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LK++ RAG G+DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +L
Sbjct: 66 NLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSL 125
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
K G+W++ G EL GKTL ++G G +G+E
Sbjct: 126 KEGKWEKKALKGKELLGKTLGLIGFGNIGQE 156
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 139 bits (337), Expect = 3e-32
Identities = 64/150 (42%), Positives = 100/150 (66%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEAAE 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LKVVGRAG G+DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++
Sbjct: 63 NLKVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASM 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGR 511
KAG+W++ + G E+ K ++G+GR+GR
Sbjct: 123 KAGKWEKKKFQGHEVTAKVAGVVGIGRIGR 152
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 138 bits (335), Expect = 5e-32
Identities = 70/155 (45%), Positives = 97/155 (62%), Gaps = 1/155 (0%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 223
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 224 VLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 403
+++ KLKVVGRAG GVDNID+ A K+G+ V N P +N +SACELT L+L +R++
Sbjct: 61 LMNMAKKLKVVGRAGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIA 120
Query: 404 PASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
LK G WDR + G+EL KTL I+GLGR+G
Sbjct: 121 KTDRFLKEGNWDRDSFMGTELFNKTLGIIGLGRIG 155
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 138 bits (334), Expect = 7e-32
Identities = 59/152 (38%), Positives = 102/152 (67%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 232
+ VL+ D + + +L G+ K + ++L + ++D L VRSAT+VT ++LD
Sbjct: 2 VARVLVSDDLSPEAVRILQEAGLEVDVKVGLKPDQLERIVGDYDGLAVRSATKVTAQLLD 61
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
+LKV+GRAG GVDN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+
Sbjct: 62 KAARLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAAT 121
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
++KAG+W++ + G ELAG+TL ++G+G +G
Sbjct: 122 GSVKAGKWEKKRFQGHELAGRTLGVVGIGNIG 153
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 138 bits (334), Expect = 7e-32
Identities = 64/150 (42%), Positives = 96/150 (64%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAAAS 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LKV+GRAG GVDN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ +
Sbjct: 64 RLKVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATAST 123
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGR 511
KAG+W+++ + G ELAGKT ++GLG VGR
Sbjct: 124 KAGKWEKSRFMGRELAGKTAGVIGLGNVGR 153
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 137 bits (332), Expect = 1e-31
Identities = 63/157 (40%), Positives = 104/157 (66%)
Frame = +2
Query: 41 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 220
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 221 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 400
E+L +LKV+GRAGAG+DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR +
Sbjct: 60 EILKNADRLKVIGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRI 119
Query: 401 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
A+ + KAG+W+++ + G EL KTL I+G+G++G+
Sbjct: 120 PQANASNKAGKWEKSKFMGVELFQKTLGIVGMGKIGQ 156
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 137 bits (331), Expect = 2e-31
Identities = 67/150 (44%), Positives = 100/150 (66%), Gaps = 1/150 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIENA 62
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LKV+GRAG GVDNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +
Sbjct: 63 PRLKVIGRAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQS 122
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVG 508
++ GRWD+ + G+EL +TL I+GLG++G
Sbjct: 123 MREGRWDKKRFMGTELFHQTLGIIGLGKIG 152
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 137 bits (331), Expect = 2e-31
Identities = 67/156 (42%), Positives = 104/156 (66%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 226
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 227 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 406
++A LK++GRAG GVDN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++
Sbjct: 74 IEAADNLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQ 133
Query: 407 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
A+ +LKA W R + G E+ GKTL ++GLGR+G E
Sbjct: 134 ANASLKAREWKRNKFMGVEVKGKTLGVIGLGRIGSE 169
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 136 bits (329), Expect = 3e-31
Identities = 70/149 (46%), Positives = 92/149 (61%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALDKAR 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LKV+GRAG G DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL
Sbjct: 63 NLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQAL 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
G WDR Y G E+ GKTL I+GLGR+G
Sbjct: 123 HEGIWDRKKYMGVEVKGKTLGIIGLGRIG 151
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 135 bits (326), Expect = 6e-31
Identities = 66/118 (55%), Positives = 84/118 (71%)
Frame = +2
Query: 155 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 334
ELL +P DA++VRSAT+V E L A +LKV+ RAG G+DN+DV +A + GV V+NAP
Sbjct: 44 ELLAALPEADAILVRSATKVDAEALAAARRLKVIARAGVGLDNVDVRAATQAGVMVVNAP 103
Query: 335 GANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+N +SA EL LML ARH+ PA ALK G W RA YTG+EL KT+ I+GLGR+G
Sbjct: 104 TSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTGTELYEKTVGIVGLGRIG 161
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 133 bits (321), Expect = 3e-30
Identities = 66/149 (44%), Positives = 99/149 (66%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E+++ G
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLKV+GRAG GVDNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A
Sbjct: 62 KLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAA 121
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
G + R + G EL GKT+ I+GLGR+G
Sbjct: 122 LNGDFRRDRFKGVELNGKTVGIIGLGRIG 150
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 131 bits (317), Expect = 8e-30
Identities = 65/152 (42%), Positives = 99/152 (65%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV +A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEAAK 143
Query: 242 -KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A +
Sbjct: 144 GRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADAS 203
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+KAG+W+R+ Y G L GKTLA++G G+VG E
Sbjct: 204 IKAGKWERSKYVGVSLVGKTLAVMGFGKVGTE 235
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 131 bits (316), Expect = 1e-29
Identities = 63/151 (41%), Positives = 93/151 (61%)
Frame = +2
Query: 59 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++DAG
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
LK++ R G G+DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + +
Sbjct: 62 QNLKILARYGVGLDNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAK 121
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+KAG W + Y G E+AGKT+ I+G GR+GR
Sbjct: 122 VKAGEWPKGKYIGIEIAGKTMGIVGFGRIGR 152
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 130 bits (315), Expect = 1e-29
Identities = 67/149 (44%), Positives = 96/149 (64%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEAAG 61
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LK +GRAG GVDNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L
Sbjct: 62 RLKAIGRAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASL 121
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
+ G W+RA + G E+A KTL ++GLG VG
Sbjct: 122 RRGEWNRAAFKGVEVAEKTLGLVGLGHVG 150
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 130 bits (314), Expect = 2e-29
Identities = 57/149 (38%), Positives = 101/149 (67%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++ AG
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAGS 90
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LK++GRAG GVDNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++
Sbjct: 91 QLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSV 150
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
K +W+R + G+E+ KTL ++GLG++G
Sbjct: 151 KESKWERKQFIGTEVYKKTLGVVGLGKIG 179
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 130 bits (313), Expect = 2e-29
Identities = 66/151 (43%), Positives = 91/151 (60%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLK + RAG GVDNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++
Sbjct: 72 KLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASV 131
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
K G+W++ +TG +L GKT I+GLGRVGR+
Sbjct: 132 KEGKWEKKKFTGQQLTGKTFGIIGLGRVGRQ 162
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 130 bits (313), Expect = 2e-29
Identities = 65/149 (43%), Positives = 99/149 (66%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRAAK 69
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LKVV RAG GVDN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++L
Sbjct: 70 QLKVVARAGVGVDNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSL 129
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
K+G+W+R+ + G E+ GKTL+I+GLG+VG
Sbjct: 130 KSGKWERSKFVGVEVKGKTLSIIGLGKVG 158
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 129 bits (311), Expect = 4e-29
Identities = 68/152 (44%), Positives = 94/152 (61%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
KLKVVGRAG GVDN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A +
Sbjct: 64 EKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHES 123
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ +WDR + G EL G+ L I+GLG +G +
Sbjct: 124 MLNYKWDRKKFMGEELYGRILGIIGLGNIGSQ 155
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 128 bits (309), Expect = 7e-29
Identities = 63/153 (41%), Positives = 99/153 (64%), Gaps = 1/153 (0%)
Frame = +2
Query: 59 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++A
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
L+V+ RAG GVDNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A
Sbjct: 63 SGNLRVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHK 122
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ AG+W+R + G EL KTL I+G G++G E
Sbjct: 123 SAAAGKWEREKFKGVELFKKTLGIIGTGKIGTE 155
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 128 bits (308), Expect = 1e-28
Identities = 61/116 (52%), Positives = 81/116 (69%)
Frame = +2
Query: 167 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 346
E+ DAL+VRSAT+VT+++ + LK+VGRAG GVDNID+D A K GV VINAP N
Sbjct: 37 ELHTFDALLVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNT 96
Query: 347 LSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+S E T ++ L RH+ A+ ++K+ W+R Y GSEL GKTL I+GLGR+G E
Sbjct: 97 ISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVGSELYGKTLGIVGLGRIGSE 152
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 127 bits (307), Expect = 1e-28
Identities = 60/122 (49%), Positives = 87/122 (71%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
KE+LL ++ DAL+VRSA V +L+ +L+V+GRAG GVDNI++++A +KG+ V+N
Sbjct: 34 KEQLLEQLKGADALIVRSAVFVDAAMLEHADQLRVIGRAGVGVDNIELEAATRKGIAVMN 93
Query: 329 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
PGANA++ E T LML LAR + A+ + AG+W++ G+EL GKTL I+GLGR+G
Sbjct: 94 TPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQGTELRGKTLGIVGLGRIG 153
Query: 509 RE 514
E
Sbjct: 154 LE 155
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 126 bits (305), Expect = 2e-28
Identities = 66/153 (43%), Positives = 98/153 (64%), Gaps = 1/153 (0%)
Frame = +2
Query: 59 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEAS 171
Query: 239 V-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A
Sbjct: 172 SGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADA 231
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++K+G+W R Y G L GKTLA++G G+VG E
Sbjct: 232 SVKSGKWQRNKYVGVSLVGKTLAVMGFGKVGSE 264
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 126 bits (304), Expect = 3e-28
Identities = 58/152 (38%), Positives = 95/152 (62%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
+L++D + + +LL A GI + K+ EEL + DA ++RS +T E L+
Sbjct: 4 ILVLDDIAQEGIDLLEASEGIEYEVRTKLKGEELRQSLNEFDAAILRSGVTITPESLEGN 63
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+L+ + RAG G DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +
Sbjct: 64 TRLRALVRAGVGTDNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQS 123
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
L GRWDR + G+++AGKTL I+G+GR+GRE
Sbjct: 124 LVEGRWDRKKFMGTQVAGKTLGIVGMGRIGRE 155
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 126 bits (304), Expect = 3e-28
Identities = 63/150 (42%), Positives = 96/150 (64%), Gaps = 1/150 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VLI D + ++L I ++ +S EE+ + + D +++RSAT++T+EVL
Sbjct: 4 VLITDNLSPAGLKILEDNPEIEVDIRSGLSPEEVREALKSADGIIIRSATKLTEEVLKGQ 63
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LK + RAG GVDNID +A ++G+ V+N P N S E T LM+ LAR++ PA
Sbjct: 64 PRLKAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYAT 123
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+K G+W+R TG+++AGKTLAI+GLGR+G
Sbjct: 124 MKEGKWERKKLTGTQVAGKTLAIIGLGRIG 153
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 125 bits (301), Expect = 7e-28
Identities = 62/126 (49%), Positives = 86/126 (68%), Gaps = 4/126 (3%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNIDVDSAGKKGV 316
K+ELL++I D LVVRSAT+VTKEV+DA G KLK++ RAG GVDNIDV A KG+
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGL 91
Query: 317 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 496
V N P A++ S EL M ++R + A+ ++ G+W++ YTG+E+ GKTL ++G
Sbjct: 92 TVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTGTEIFGKTLGLIGF 151
Query: 497 GRVGRE 514
GR+ RE
Sbjct: 152 GRIARE 157
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 124 bits (300), Expect = 9e-28
Identities = 61/151 (40%), Positives = 95/151 (62%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ D + L G + +EE+ + + DA VVRS T+VT+E+++
Sbjct: 4 ILVTDPIHEDALRKLEELGEVVVLE-DADEEEIREHVRDADAWVVRSGTRVTRELIEEAK 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LKV+ RAG GVDNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A ++
Sbjct: 63 NLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSV 122
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ G WDR + G ELAGKTL ++GLGR+G++
Sbjct: 123 RRGEWDRKRFMGVELAGKTLGLIGLGRIGQQ 153
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 123 bits (297), Expect = 2e-27
Identities = 60/151 (39%), Positives = 94/151 (62%), Gaps = 2/151 (1%)
Frame = +2
Query: 62 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+AG
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64
Query: 239 V-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
KLK V RAG G+DN+D+ +A K GV V+N P N ++ E T +M+ L R++ +
Sbjct: 65 APKLKAVARAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTL 124
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+L++G+W++ G E+ KTL ++G G++G
Sbjct: 125 SLRSGQWEKKKLQGREVFNKTLGVIGFGKIG 155
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 123 bits (296), Expect = 3e-27
Identities = 67/151 (44%), Positives = 94/151 (62%), Gaps = 1/151 (0%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLME-IPNHDALVVRSATQVTKEVLDAGV 241
L+ D V ELL GI + K E+L E I D L+VRS T+V +EV++A
Sbjct: 5 LVTDKVHPAGLELLREKGIEVVEDLEAYKPEVLKERIKGFDVLIVRSRTKVRREVIEAAD 64
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLKV+ RAG+G+DNID+++A +KG+ V+NAP A + EL +M+VLAR + L
Sbjct: 65 KLKVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKL 124
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
G W++ + G ELAGKTL ++G GR+GRE
Sbjct: 125 LEGEWEKVM--GFELAGKTLGVVGFGRIGRE 153
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 122 bits (295), Expect = 4e-27
Identities = 65/152 (42%), Positives = 96/152 (63%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VLI D + + + L A I +++EL +I + DA++VRS TQVT+ +++
Sbjct: 5 VLISDPLSEEGLKPLQEAENIEVVINPGWNEQELSDQIDSFDAILVRSQTQVTRALIEKA 64
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
LK++GRAG GVDNID+++A + GV V+NAP N SA E T +++ L+R++ A A
Sbjct: 65 SNLKIIGRAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHA 124
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
LK +WDR + G EL KTL I+GLGR+G E
Sbjct: 125 LKQKQWDRKRFVGVELKQKTLGIVGLGRIGAE 156
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 122 bits (295), Expect = 4e-27
Identities = 67/151 (44%), Positives = 89/151 (58%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V +A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEAAS 66
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
L +VGRAG GVDNID+D+A + GV V NAP N +A E T + AR + A L
Sbjct: 67 DLIIVGRAGIGVDNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARL 126
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ G W ++ Y G+E+ GKTL ++GLGRVG+E
Sbjct: 127 RTGEWAKSEYLGTEVNGKTLGVVGLGRVGQE 157
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 122 bits (294), Expect = 5e-27
Identities = 62/152 (40%), Positives = 96/152 (63%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
+L+ D + K A L G S E++L + + A+ VRS T++T+EV+ A
Sbjct: 3 ILVADKISPKGVAYLRQQEGFEVVEAYGSSPEKVLELVKDVHAIAVRSETKITREVIAAA 62
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LKVVGRAG GVDN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +
Sbjct: 63 PQLKVVGRAGVGVDNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAAS 122
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++ G+WDR ++G EL KTL ++G+GR+G E
Sbjct: 123 MREGKWDRKSFSGVELFKKTLGVIGMGRIGGE 154
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 122 bits (294), Expect = 5e-27
Identities = 58/121 (47%), Positives = 84/121 (69%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
+ +LL +P DAL+VRSAT V EVL A KLK+V RAG G+DN+DVD+A +GV V+N
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVN 93
Query: 329 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
AP +N SA E L+L +R + A +L+A W R+ ++G+E+ GKT+ ++GLGR+G
Sbjct: 94 APTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLGRIG 153
Query: 509 R 511
+
Sbjct: 154 Q 154
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 120 bits (290), Expect = 1e-26
Identities = 60/136 (44%), Positives = 89/136 (65%), Gaps = 1/136 (0%)
Frame = +2
Query: 104 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVD 280
L+ G + + +EE L +P++DAL+ RS T+V +E+LDA G +LKV+GR G GVD
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVD 92
Query: 281 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 460
NID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WDR + G
Sbjct: 93 NIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLGL 151
Query: 461 ELAGKTLAILGLGRVG 508
EL KTL I+GLGR+G
Sbjct: 152 ELTDKTLGIVGLGRIG 167
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 120 bits (289), Expect = 2e-26
Identities = 57/151 (37%), Positives = 93/151 (61%), Gaps = 2/151 (1%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISK--EELLMEIPNHDALVVRSATQVTKEVLDA 235
VL+ D + ++ G+ + K E+LL I +D L +RSAT+VT++++ A
Sbjct: 10 VLVSDKLSPTAVQIFKDRGVDVDYLPDLGKDKEKLLEVIGEYDGLAIRSATKVTEKLIAA 69
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
KLKVVGRAG GVDN+D+ +A ++G+ V+N P N+++ E LM +AR + A T
Sbjct: 70 AKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADT 129
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+ +AG+W++ + G E+ GKTL ++G G +G
Sbjct: 130 STRAGKWEKNRFMGVEITGKTLGVVGCGNIG 160
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 120 bits (289), Expect = 2e-26
Identities = 60/151 (39%), Positives = 94/151 (62%), Gaps = 1/151 (0%)
Frame = +2
Query: 59 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEK 63
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
LKV+ RAG GVDNID+D+A +G+ VINAP N +SA E + ++L +AR++ A
Sbjct: 64 ASNLKVIARAGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHA 123
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+LK W+R + G EL KTL ++G GR+G
Sbjct: 124 SLKNKEWNRKAFKGVELYQKTLGVIGAGRIG 154
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 118 bits (285), Expect = 6e-26
Identities = 64/155 (41%), Positives = 97/155 (62%)
Frame = +2
Query: 50 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
++ VLI D + C +LL G+ K +SKEEL++EI + + T+VT +V
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCET------TKVTADVT 58
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
+ KL++VGRAG G+DN+++++A K + V+N P +LSA ELTC +++ L R + P
Sbjct: 59 NTAEKLQLVGRAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP- 117
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
G+WD+ + G+EL GKTL ILGLGR+GRE
Sbjct: 118 ------GKWDQEEFMGTELNGKTLGILGLGRIGRE 146
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 118 bits (285), Expect = 6e-26
Identities = 58/127 (45%), Positives = 82/127 (64%)
Frame = +2
Query: 131 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 310
T + K+ L +I D L+VRSAT+VTKE+L+ KLK+V RAG G+DNIDVD+A K
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILEHADKLKIVARAGMGLDNIDVDTAKLK 86
Query: 311 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAIL 490
G+ V+N PG N+LS EL ++L + RH+ + LK +W++ G EL+ KT I+
Sbjct: 87 GITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEGFELSQKTFGII 146
Query: 491 GLGRVGR 511
G G VG+
Sbjct: 147 GFGYVGK 153
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 118 bits (284), Expect = 8e-26
Identities = 64/154 (41%), Positives = 92/154 (59%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 226
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 227 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 406
+ GV LK++ RAG G+DNID + A K+ + ++ APGA+ SA ELT L++ AR +
Sbjct: 75 IRYGVNLKIIARAGIGLDNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYD 134
Query: 407 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+ K G + + G ELAGKT+ I+G GR+G
Sbjct: 135 SMNMAKGGIFKK--IEGIELAGKTIGIVGFGRIG 166
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 117 bits (282), Expect = 1e-25
Identities = 64/137 (46%), Positives = 88/137 (64%), Gaps = 13/137 (9%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVG 319
+S ELL ++ DAL+VRS T+VT+EVL+AG +L+VVGRAG G+DN+D+ +A + G
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAGRGRLRVVGRAGVGIDNVDLQAATEAGCL 165
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKA------------GRWDRALYTGSE 463
V+NAP AN ++A E L+ +AR+V A ALKA G+W R Y G
Sbjct: 166 VVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFTAQGKWQRTKYVGVS 225
Query: 464 LAGKTLAILGLGRVGRE 514
L GKTLA++G G+VG E
Sbjct: 226 LVGKTLAVMGFGKVGSE 242
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 116 bits (278), Expect = 4e-25
Identities = 64/142 (45%), Positives = 93/142 (65%), Gaps = 4/142 (2%)
Frame = +2
Query: 98 ELLNAYGIATT----TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRA 265
E+L A G A T+A + ++LL +P DAL+V VT EV++AG +L+V+ +
Sbjct: 20 EILEAAGSAAVRPHETRA-MPADDLLARVPEADALIV-GMDLVTAEVIEAGPRLRVIAKH 77
Query: 266 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 445
G GVDNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W +
Sbjct: 78 GVGVDNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK- 136
Query: 446 LYTGSELAGKTLAILGLGRVGR 511
LY G ELAG+TL ++G GR+GR
Sbjct: 137 LY-GPELAGRTLGVIGFGRIGR 157
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 113 bits (273), Expect = 2e-24
Identities = 58/153 (37%), Positives = 91/153 (59%), Gaps = 1/153 (0%)
Frame = +2
Query: 53 IKSVLIVDGV-GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
+ VL+ + + G L+ + + + + L +I N AL+VR+ T+V +E++
Sbjct: 1 MSDVLVTENIQGVSMNRLIQEHDVEFDAYLWQNIDLLKQKIQNTRALIVRNQTKVDRELI 60
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
DA +LK++ RAGAG+DN+D + A +KG+ V P AN+LS ELT LML L R + A
Sbjct: 61 DAAPELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEA 120
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
G W+R +TG+EL GK+ ++GLGR+G
Sbjct: 121 RQDTLTGGWNRLKFTGTELYGKSFGLIGLGRIG 153
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 112 bits (269), Expect = 5e-24
Identities = 56/123 (45%), Positives = 86/123 (69%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+S EEL+ + + DAL+V + +VT++V++AG KLKV+ R G G DN+D+++A KKG+ V
Sbjct: 40 LSAEELIPLVKDADALIVGN-DKVTEDVINAGKKLKVISRYGVGYDNVDLNAAKKKGIVV 98
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
N P AN S +L LMLVLAR+++ +K+G W R + G+E+ GKTL I+GLG+
Sbjct: 99 TNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--GTEIYGKTLGIIGLGK 156
Query: 503 VGR 511
+G+
Sbjct: 157 IGK 159
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 110 bits (264), Expect = 2e-23
Identities = 55/152 (36%), Positives = 85/152 (55%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++ +
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEIIRS 64
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
K++ R G G+DNID+ +A GV VINA + EL +ML +AR + A
Sbjct: 65 AKDCKIIARVGVGLDNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADR 124
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
++ G+W + G+EL GK L I+GLG +GR
Sbjct: 125 GIRGGKWLKGELGGTELKGKYLGIVGLGNIGR 156
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 109 bits (263), Expect = 3e-23
Identities = 60/154 (38%), Positives = 88/154 (57%), Gaps = 3/154 (1%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++D +
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI 62
Query: 242 K---LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
K LK++ R G GVDNIDV A + G+ V N P A++ S E+ M LAR + ++
Sbjct: 63 KGGKLKLIIRGGVGVDNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSN 122
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+KAG W + Y G EL GKTL I+G+GR+G E
Sbjct: 123 ITMKAGLWKKKDYVGVELEGKTLGIIGMGRIGSE 156
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 79.4 bits (187), Expect(2) = 2e-22
Identities = 39/77 (50%), Positives = 48/77 (62%)
Frame = +2
Query: 284 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 463
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 464 LAGKTLAILGLGRVGRE 514
L GKTL I+GLGR+GRE
Sbjct: 106 LYGKTLGIVGLGRIGRE 122
Score = 48.4 bits (110), Expect(2) = 2e-22
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +2
Query: 41 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 175
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 105 bits (252), Expect = 6e-22
Identities = 55/151 (36%), Positives = 89/151 (58%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFAA 62
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LK++ RAG GV+NI +D+A KG+ V N P + + E +M+ LAR + A +
Sbjct: 63 KRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHES 122
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ G+W + GS++ KTL ++G G++GR
Sbjct: 123 MSQGKWQSTEFLGSDINDKTLGVIGGGKIGR 153
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 104 bits (249), Expect = 1e-21
Identities = 54/150 (36%), Positives = 88/150 (58%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIIDNAK 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LK++ RAG G D+IDVD A +KG+ ++ APG++ S ELT ++ AR ++
Sbjct: 64 RLKIIARAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENT 123
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ D G EL+GKTL I+G GR+GR
Sbjct: 124 RKN--DFTKLKGIELSGKTLGIIGYGRIGR 151
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 103 bits (247), Expect = 2e-21
Identities = 63/171 (36%), Positives = 97/171 (56%), Gaps = 24/171 (14%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRAAK 69
Query: 242 KLKVVGRAGAGVDNI------------------------DVDSAGKKGVGVINAPGANAL 349
+LKVV RAG GVDN+ DV+ A K G+ V+N+P N
Sbjct: 70 QLKVVARAGVGVDNVGELAQPPLPPSPSLGSWPLTSHRTDVEEATKLGIVVVNSPSGNIG 129
Query: 350 SACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
+A E T L++ +AR++ A ++LK+G+W+R+ + G E+ GKTL+I+GLG+
Sbjct: 130 AAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEVKGKTLSIIGLGK 180
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 102 bits (245), Expect = 4e-21
Identities = 52/153 (33%), Positives = 88/153 (57%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 232
++ VLI + A +L+ G +L+ + + L+VRS ++T E++D
Sbjct: 1 MRKVLIPTKLDKFAATMLSDRGYNVVLDGATPLADLVKANSDAEVLIVRSE-KITPEIID 59
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
+LK++ RAGAG + ID+ A K + V+N PGAN+ + E +ML +RH++PA
Sbjct: 60 LLPQLKLIVRAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPAD 119
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ + G W+++ + G EL GKT+ ILGLG +G+
Sbjct: 120 ISTRKGDWEKSKFMGRELTGKTVGILGLGHIGQ 152
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 102 bits (245), Expect = 4e-21
Identities = 48/153 (31%), Positives = 94/153 (61%), Gaps = 2/153 (1%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
+L +G G + +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ +
Sbjct: 160 NPQLLAIGCFCIGTNQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTH 219
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++AG W++ E+ GKTL I+G G +G +
Sbjct: 220 EMRAGIWNKLSKNCWEIRGKTLGIVGYGHIGSQ 252
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 102 bits (244), Expect = 6e-21
Identities = 59/155 (38%), Positives = 92/155 (59%)
Frame = +2
Query: 50 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
+I VLI D + C ++L G+ ++KEEL+ E+ + + L ++SAT+VT + +
Sbjct: 5 NICKVLISDSLDPCCQKILQDGGLQN-----LNKEELITELQDCEGLTIQSATKVTADAV 59
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
+A KL+VVG AG G+DN+D+++A +K + V+N N+LS ELTC + L A P
Sbjct: 60 NAAQKLQVVGSAGTGMDNVDLEAAMRKSILVMNTSNGNSLSPVELTCGMNLCQAD--FPG 117
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+ + + G+ L GKTL LGLGR+GRE
Sbjct: 118 NNFNERWQMGPEEVHGATLTGKTLGNLGLGRIGRE 152
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 101 bits (241), Expect = 1e-20
Identities = 55/149 (36%), Positives = 84/149 (56%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LIVD + A E A G + ++ + L I ++D + VR+ ++ +E++DAG
Sbjct: 6 ILIVDELHAIFKERAAAMGYEVHDEPNFTRAQTLAAIADYDGIAVRTKFRIDRELIDAGT 65
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLK + RAGAG+DNID A ++ + +INAP N + E LML L + A +
Sbjct: 66 KLKFIARAGAGLDNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEI 125
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVG 508
+ G+WDR G EL GKT+ I+G G +G
Sbjct: 126 RKGKWDREGNRGYELKGKTVGIIGYGFMG 154
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 100 bits (240), Expect = 2e-20
Identities = 55/142 (38%), Positives = 79/142 (55%), Gaps = 4/142 (2%)
Frame = +2
Query: 98 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAG 274
ELL + + K + IS +EL + + DAL+ +T+VTKEV+DA LK+V GAG
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDAAPSLKIVANYGAG 75
Query: 275 VDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRA 445
DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 76 YDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPL 135
Query: 446 LYTGSELAGKTLAILGLGRVGR 511
+ G E+ GKT+ I+GLG +G+
Sbjct: 136 FFLGREVHGKTIGIIGLGEIGK 157
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 99.5 bits (237), Expect = 4e-20
Identities = 54/150 (36%), Positives = 85/150 (56%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 244
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D+ K
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIIDSCTK 66
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
L+ + RAGAGVDNID + +K + + +A N ++ E T L+L L ++V + T +K
Sbjct: 67 LQFIARAGAGVDNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVRSDTEVK 126
Query: 425 AGRWDRALYTGSELAGKTLAILGLGRVGRE 514
W R G EL T+ ++G G +G+E
Sbjct: 127 DAIWLREENRGYELESLTVGLIGYGNMGKE 156
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 98.3 bits (234), Expect = 9e-20
Identities = 54/152 (35%), Positives = 86/152 (56%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ D + A G+ + ++ +EL + LVVRS QV +V DA
Sbjct: 3 ILVADAFPTERLADFQALGLEVAHRPDVAVQELAAAARDAAILVVRSK-QVQADVFDAAP 61
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
L +V RAGAGV+ IDV +A ++GV V N PG N+++ EL L++ L R + L
Sbjct: 62 GLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALL 121
Query: 422 KAGRWDRALYTGSE-LAGKTLAILGLGRVGRE 514
+AG+WD+ ++ ++ L G+TL + G+G +GRE
Sbjct: 122 RAGKWDKKTFSEAQGLYGRTLGVAGVGSIGRE 153
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 97.9 bits (233), Expect = 1e-19
Identities = 54/151 (35%), Positives = 83/151 (54%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ + + LL G + + L+ + + DA++ R+ +++VL+
Sbjct: 5 VLVPQKIAQEGIRLLEENGASIVVPPSHDEATLVEYVSDVDAIIARTEIY-SEKVLENAN 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LK++ R G GVDNIDV +A K G+ V N P AN + EL T ML RH++P A+
Sbjct: 64 RLKIIARHGIGVDNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAV 123
Query: 422 KAGRWD-RALYTGSELAGKTLAILGLGRVGR 511
+AG +D R G EL GKT+ I+G G +GR
Sbjct: 124 RAGNFDIRNQLFGYELNGKTVGIIGFGNIGR 154
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/153 (33%), Positives = 90/153 (58%), Gaps = 1/153 (0%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 232
+K VL+ + + + +LL T S++ L+ + + DA+++R+ +++T+EV++
Sbjct: 1 MKKVLLSEEIHPEGRKLLEGK-FEIVTAPDTSQQTLISMVKDVDAIILRTRSKITREVIE 59
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
LK++ R GAGVDNIDV++A +KG+ V N P N LS E T ++L L++ +
Sbjct: 60 NAPHLKIISRTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMD 119
Query: 413 TALKAGRWD-RALYTGSELAGKTLAILGLGRVG 508
A+++G W R E+ GK L I+G+G +G
Sbjct: 120 KAVRSGNWGARNSNISVEIEGKVLGIVGMGNIG 152
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 97.9 bits (233), Expect = 1e-19
Identities = 55/150 (36%), Positives = 85/150 (56%), Gaps = 1/150 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VL+ D A+ L +G + + E+L + + LVVRS T V V++A
Sbjct: 3 VLLADAFPAEHVSALTEHGHDCDYQPDTTTEQLPDRLTGREVLVVRS-TAVPSAVIEAAD 61
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
L++V RAG+G + ID +SA ++GV V N PG NA++ EL LML L R V L
Sbjct: 62 SLRLVIRAGSGTNTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDL 121
Query: 422 KAGRWDRALYTGSE-LAGKTLAILGLGRVG 508
+AGRWD+ Y+ + + G+ + ++GLG++G
Sbjct: 122 RAGRWDKKRYSRARGIHGRRVGVVGLGQIG 151
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 97.9 bits (233), Expect = 1e-19
Identities = 49/151 (32%), Positives = 85/151 (56%)
Frame = +2
Query: 59 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
++LI+D + LL + GI + I++ E+L + ++ L+VRS T + ++++
Sbjct: 4 NILIIDKMHPSITSLLESRGIQGDYRPDITRAEILTIVDKYEGLMVRSKTAIDEDLIGRA 63
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
+LKV+ RAGAG+D ID+ +A +G+ V+NAP N + E T ++L L +V A
Sbjct: 64 SRLKVIARAGAGLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWE 123
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+K W R G EL K + ++G G +G+
Sbjct: 124 VKNFAWKREANRGVELMDKVVGVIGYGNMGK 154
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 97.5 bits (232), Expect = 2e-19
Identities = 52/152 (34%), Positives = 80/152 (52%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
+ VLI + ++L G +A + EL P+ + ++VRS ++T EV+D
Sbjct: 3 QKVLIPTKLSTAAKDILEGNGFTVVQEAGVDLVELAKAHPDTEGMIVRSE-KLTPEVIDL 61
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
LK V RAGAG + ID+ A K + V+N PGAN+ + E +M+ AR +
Sbjct: 62 FPNLKAVVRAGAGYNTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDR 121
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ +AG W +A G EL GKT+ I G G +G+
Sbjct: 122 STRAGEWKKAQLQGFELTGKTVGIAGFGNIGQ 153
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 96.3 bits (229), Expect = 4e-19
Identities = 51/159 (32%), Positives = 86/159 (54%), Gaps = 5/159 (3%)
Frame = +2
Query: 50 DIKSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNH---DALVVRSATQV 214
D++ L++ G + A+ + G A + + + L EI D ++VR ++
Sbjct: 9 DMRYKLLITGPALTAEATAIAARRGAALVDNPRYASPQELAEITAREQPDGIIVRQG-KI 67
Query: 215 TKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 394
+V+ A KLK + + G G DNIDV++A ++G+ V A GAN+ S EL LM +AR
Sbjct: 68 DDQVIGASQKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAR 127
Query: 395 HVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ +K G WD+A G++L G++L ++G G +GR
Sbjct: 128 EIPHLDARIKTGHWDKATTKGAQLLGRSLGVIGFGEIGR 166
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 95.9 bits (228), Expect = 5e-19
Identities = 43/109 (39%), Positives = 71/109 (65%)
Frame = +2
Query: 188 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 367
+VVR + ++ + A L+V+ + G GVDNIDVD+A ++ + V+ A GANALS E
Sbjct: 76 VVVRMG-RFSEAAIKAAPSLRVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHA 134
Query: 368 CTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
TL+ + + +VP + ++AGRW++A Y+G ELAG + ++G G + R+
Sbjct: 135 ITLLFAVVKRIVPLDSGIRAGRWEKAGYSGKELAGMIIGLVGFGAIARQ 183
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 95.9 bits (228), Expect = 5e-19
Identities = 52/120 (43%), Positives = 69/120 (57%), Gaps = 1/120 (0%)
Frame = +2
Query: 158 LLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPG 337
LL + DAL+VR+ TQV +L+ L+VVGR G G+DNIDV + +G+ VI A G
Sbjct: 38 LLDALAGADALIVRNRTQVDAALLERAPALRVVGRLGVGLDNIDVAACRDRGIRVIPASG 97
Query: 338 ANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGRE 514
ANA S E T +L R S + G+W RA L G E GKTL ++G G +GR+
Sbjct: 98 ANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSEGREALGKTLGLIGFGDIGRQ 157
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 94.3 bits (224), Expect = 1e-18
Identities = 52/151 (34%), Positives = 89/151 (58%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
VLI + + +LL G ++E L+ + + DA+++R+A ++++ V++
Sbjct: 5 VLIPQPIAKEGIDLLEKEGAEVIIPPDYNEETLISHVSDVDAILIRTA-KLSRVVIEKAS 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLKV+ R G GVDNID+++A +G+ V NAP AN + E TL+L +R ++ +AL
Sbjct: 64 KLKVIARHGIGVDNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSAL 123
Query: 422 KAGRWD-RALYTGSELAGKTLAILGLGRVGR 511
+ G ++ R G EL GKTL ++G G +G+
Sbjct: 124 RNGDFEVRNRKFGIELKGKTLGVVGFGNIGQ 154
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 94.3 bits (224), Expect = 1e-18
Identities = 49/154 (31%), Positives = 86/154 (55%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 226
V +VLI + + E L S+E L I + +ALV RS +V+ ++
Sbjct: 20 VHTMNVLIASSIDGEAIERLEQEHQVIRAFPNSSEESLHALIRDCEALVFRSGIRVSADL 79
Query: 227 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 406
+ +LK++ RAG+G+DN+DV+ A K+GV ++ P +A + E+ ML L+R ++
Sbjct: 80 MGCAPRLKLLVRAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLE 139
Query: 407 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
A +++ GRW++ ++G L KTL ++G+G G
Sbjct: 140 ADRSMRNGRWEKHEFSGYLLRDKTLGVVGIGNTG 173
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 93.9 bits (223), Expect = 2e-18
Identities = 55/154 (35%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELL-NAYGIATTTKAKISKEELLMEI-PNHDALVVRSATQVTKEVL 229
K++++ D + ++L N I A K++L+ EI P D + RS+T V L
Sbjct: 4 KTIVVCDHIHQSGLDILANDSEIKLINAADEPKDKLIAEIIPLADVAITRSSTDVDAAFL 63
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
++ K+ + RAG GVDN+D+ + K+G+ V+N P AN ++A ELT ML R A
Sbjct: 64 ESAKKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYA 123
Query: 410 STALKAGR-WDRALYTGSELAGKTLAILGLGRVG 508
LK R W R + G+EL K L I+G G +G
Sbjct: 124 HNNLKLDRVWRRQDWYGTELKDKKLGIIGFGNIG 157
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 93.9 bits (223), Expect = 2e-18
Identities = 65/169 (38%), Positives = 92/169 (54%), Gaps = 9/169 (5%)
Frame = +2
Query: 32 KPRMVVDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRS 202
K V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRS
Sbjct: 6 KANQQVNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRS 63
Query: 203 ATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLM- 379
ATQV K+++D LK++GR G G+DNIDV A +KG+ VIN P A++ S EL +
Sbjct: 64 ATQVRKDIIDNCPSLKLIGRGGVGMDNIDVAYAKEKGLHVINTPAASSESVAELVFAHLF 123
Query: 380 -----LVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
L A +P K + ++ GSEL GKTL ++G GR+G+
Sbjct: 124 GGVRFLYDANRNMPLEGDSKFKQLKKSYAGGSELRGKTLGVIGFGRIGQ 172
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 93.5 bits (222), Expect = 3e-18
Identities = 49/150 (32%), Positives = 84/150 (56%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LI + + + E L +G S++ L+ E+ + DA++VR A +T++V+ AG
Sbjct: 5 ILITESIEEEGVEYLKKFGYEIKMPRDTSEDVLIEEVKDCDAILVRMAN-ITEKVIRAGK 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
KLKV+ R G GV+N+D+ +A + + + NAP +N + E T L++ LA+ L
Sbjct: 64 KLKVISRFGVGVNNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGL 123
Query: 422 KAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ G + G +L GK L I+GLG +G+
Sbjct: 124 RKGNFKVRDILGIDLEGKVLGIVGLGSIGK 153
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 92.7 bits (220), Expect = 5e-18
Identities = 50/150 (33%), Positives = 82/150 (54%), Gaps = 1/150 (0%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 244
LIV + + LL G+ A + ++ I + DA + R+A T+ + +AG +
Sbjct: 9 LIVQPIHEEGLALLREAGVECIAPASAAMADVAAAIADCDAAITRNAGLDTRAI-EAGRR 67
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
L+V+G G G + ID+ +A + G+ V+N PGANA S EL + + L + VP A++
Sbjct: 68 LRVIGNHGTGTNMIDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVR 127
Query: 425 AGRWDRALYTG-SELAGKTLAILGLGRVGR 511
G W+ G EL+G +L I+G G++GR
Sbjct: 128 QGNWNIRYEAGLRELSGMSLGIVGFGQIGR 157
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 92.7 bits (220), Expect = 5e-18
Identities = 49/110 (44%), Positives = 69/110 (62%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DA++ R+AT ++ + A LKV+ + G GV NIDV +A ++G+ V PGANA S E
Sbjct: 75 DAVISRTAT-LSAAAIAACPTLKVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAE 133
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+T LM AR + L+AGRW RA G EL+G+TL +LG G+VG+
Sbjct: 134 MTLGLMFAAARRIAWMDAELRAGRWSRA-QDGLELSGRTLGLLGFGQVGQ 182
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/164 (33%), Positives = 85/164 (51%)
Frame = +2
Query: 23 STTKPRMVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRS 202
+T R D K++L +G+ + N +G T +EL + + DA++
Sbjct: 9 ATNYSRYCADAKAMLAAEGIDV----VENGFGRPMTF------DELSARLGDVDAVIAGV 58
Query: 203 ATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 382
T + V + +LK + R G GVDNID+D+A + G+ V NAPG NA + ELT L+L
Sbjct: 59 DTW-NERVFNLAPRLKAIARFGVGVDNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLIL 117
Query: 383 VLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
R + AL+ G WDR + G EL G+ + +LG G + R+
Sbjct: 118 SAMRRIPYLHDALRGGAWDR--FVGQELIGRRVGLLGFGNIARK 159
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/110 (44%), Positives = 66/110 (60%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DALVV VT E L G KL+ V + G GVDNID+ + + G+ V N P ANA + E
Sbjct: 53 DALVV-GLVPVTPETLTQGGKLRAVIKHGVGVDNIDIPACTEAGLPVCNTPAANADAVAE 111
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
L LM +AR + ++ AG WDR + G++L GKTL I+GLG +G+
Sbjct: 112 LAVGLMFSMARWIPQGHASVTAGGWDRRI--GTQLGGKTLGIVGLGNIGK 159
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 90.2 bits (214), Expect = 2e-17
Identities = 42/114 (36%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Frame = +2
Query: 176 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 355
N D +++R+ T T+E+++A +LK++ R G G DN+D+ +A + V V + PG+N+ +
Sbjct: 41 NIDGVILRAET-FTREMIEASPRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAV 99
Query: 356 CELTCTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGR 511
E +L+L L R ++PA+ + AG W R G EL+G+TL I+G G +G+
Sbjct: 100 AEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDLVGFELSGRTLGIVGFGAIGK 153
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 89.8 bits (213), Expect = 3e-17
Identities = 46/125 (36%), Positives = 70/125 (56%), Gaps = 3/125 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
I KE L + + DAL+ +T V KEV+DA LK++ GAG +N+D+D A ++ + V
Sbjct: 34 IDKETLKQGVKDADALISLLSTSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDV 93
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILG 493
N P A+ S ELT L+L +AR + + W + G E++GKT+ I+G
Sbjct: 94 TNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIG 153
Query: 494 LGRVG 508
LG +G
Sbjct: 154 LGEIG 158
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 89.8 bits (213), Expect = 3e-17
Identities = 48/152 (31%), Positives = 86/152 (56%), Gaps = 1/152 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+L+ + + A+ E+L A + ++ L+ + + D +++R+ VT+ ++++
Sbjct: 7 ILLYESMHARGTEVL-AEKCELVYATSLDEKNLIAQAADVDGIIIRANGAVTRALIESAP 65
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+LKV+GR G G+D ID+ A ++GV V+ P AN S E + ++LA+ + AL
Sbjct: 66 RLKVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIAL 125
Query: 422 KAGRW-DRALYTGSELAGKTLAILGLGRVGRE 514
+ G W R G+EL GK L +LG GR+GR+
Sbjct: 126 RTGDWAARNRLIGTELHGKALGVLGFGRIGRQ 157
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 89.8 bits (213), Expect = 3e-17
Identities = 54/164 (32%), Positives = 86/164 (52%), Gaps = 1/164 (0%)
Frame = +2
Query: 26 TTKPRMVVDIKSVLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRS 202
TT P ++ L+++GV ELL + G I + ++ LL +I + L +RS
Sbjct: 103 TTMPSLIDPPYHALLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRS 162
Query: 203 ATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 382
TQVT+ +LDA KL +G G + +D+D A +GV V N+P AN S EL ++
Sbjct: 163 KTQVTQAILDAAPKLLGIGCFCIGTNQVDLDYATTRGVAVFNSPFANTRSVAELVIGEII 222
Query: 383 VLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
L+R + S + G W++ E+ GKT+ I+G G +G +
Sbjct: 223 SLSRKMTQRSEEVHRGVWNKTHVGCYEVRGKTVGIVGYGHIGSQ 266
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 89.0 bits (211), Expect = 6e-17
Identities = 45/126 (35%), Positives = 72/126 (57%), Gaps = 3/126 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
IS EL+ + + D L++ +TQV ++VLD LK++ GAG +NID+ +A K+ + V
Sbjct: 34 ISHAELIRRVADADFLIIPLSTQVDQDVLDHAPHLKLIANFGAGTNNIDIAAAAKRQIPV 93
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILG 493
N P +A++ E T L++ LA +V ++ W + G L GKTL ILG
Sbjct: 94 TNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLFFLGHNLQGKTLGILG 153
Query: 494 LGRVGR 511
LG++G+
Sbjct: 154 LGQIGQ 159
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 89.0 bits (211), Expect = 6e-17
Identities = 51/125 (40%), Positives = 73/125 (58%), Gaps = 1/125 (0%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK-LKVVGRAGAGVDNIDVDSAGKKGVG 319
++++EL+ I DALV VT +V+ AG+ LK++ + G G + IDV +A G+
Sbjct: 37 LTEDELVELIKGMDALVA-GMDAVTAKVIAAGLPTLKIIAKHGVGYNTIDVAAAAAYGIP 95
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 499
V PGAN +S EL LML +ARH+ ++ G W R TGSEL GK L I+G+G
Sbjct: 96 VTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSR--MTGSELYGKVLGIIGMG 153
Query: 500 RVGRE 514
+G E
Sbjct: 154 SIGCE 158
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 88.6 bits (210), Expect = 7e-17
Identities = 56/153 (36%), Positives = 78/153 (50%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 232
I +V+ D G +L + I A +E+LL ALVVR+ TQV +++++
Sbjct: 8 IDAVITEDVWGRAFNDLGTSRSILRAPHAWQDREKLLELGSRSRALVVRNRTQVDRQLIE 67
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
A L+V+ RAG G+DNIDV A + GV V+ GANA+S E T + L R V
Sbjct: 68 ACPSLRVIARAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELD 127
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ G W+R G EL G +LG G GR
Sbjct: 128 ADCRRGGWERT--PGRELHGGVWGLLGAGATGR 158
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 88.6 bits (210), Expect = 7e-17
Identities = 51/152 (33%), Positives = 79/152 (51%), Gaps = 2/152 (1%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTT--KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 238
L+V+GV K E L A G K + E+L I + + +RS T +T++V++A
Sbjct: 14 LLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAA 73
Query: 239 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 418
KL +G G + +D+D+A K+G+ V NAP +N S EL +L+L R V A+
Sbjct: 74 EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAK 133
Query: 419 LKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
G W++ E GK L I+G G +G +
Sbjct: 134 AHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQ 165
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 88.2 bits (209), Expect = 1e-16
Identities = 49/151 (32%), Positives = 82/151 (54%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
K +LI D L + ++ + L + + AL++RS T++ +E+L
Sbjct: 3 KKILITDRFAQDSFLYLQQHSQFEVVRSDNPQHLPLEHLVSAHALIIRSRTKIDEELLKK 62
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
+L+++ +G D+ID+++ K GV V++ P AN SA +LT L+L ++ A
Sbjct: 63 ARQLQLIVTCTSGFDHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHK 122
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+KAG W+R TG ELAG+ I+GLGR+G
Sbjct: 123 MVKAGEWNRDQITGIELAGRNYGIVGLGRIG 153
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 88.2 bits (209), Expect = 1e-16
Identities = 45/131 (34%), Positives = 73/131 (55%), Gaps = 7/131 (5%)
Frame = +2
Query: 140 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
+I +E LL ++ DALV + ++ KEV + KL++V G DNID++ A K+G+
Sbjct: 33 EIPREILLKKVKEVDALVTMLSERIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIY 92
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-------ALYTGSELAGKT 478
V N P + +L L+L ARHVV +++G W + + G ++ GKT
Sbjct: 93 VTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKT 152
Query: 479 LAILGLGRVGR 511
+ I+GLGR+G+
Sbjct: 153 IGIIGLGRIGQ 163
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 87.8 bits (208), Expect = 1e-16
Identities = 50/121 (41%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Frame = +2
Query: 152 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 331
+EL + + DA +V S T+EVL LKV+ R G G D+ID D+A + GVG+
Sbjct: 41 DELATLLEDCDAAIV-STDPFTREVLAGDRNLKVIARVGVGTDSIDHDAAKEFGVGISVT 99
Query: 332 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYTGSELAGKTLAILGLGRVG 508
PG NA + + T ++L L R VV A+KAGRWDR T +EL KT+ ++G G +G
Sbjct: 100 PGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEATPTELYRKTVGLIGAGIIG 159
Query: 509 R 511
+
Sbjct: 160 K 160
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 87.8 bits (208), Expect = 1e-16
Identities = 45/122 (36%), Positives = 70/122 (57%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
SKE++ I +D + +RS + KE + LK +GR GAG++NIDV A KK + +
Sbjct: 56 SKEQIEHRIGEYDGITIRSRFTIDKEFIKKAKNLKFIGRVGAGLENIDVAYAKKKNIFLA 115
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRV 505
AP N + E T ++L L ++ A+ ++ G+WDR G EL GKT+ I+G G +
Sbjct: 116 AAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRGVELDGKTVGIIGYGNM 175
Query: 506 GR 511
G+
Sbjct: 176 GK 177
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 87.4 bits (207), Expect = 2e-16
Identities = 55/151 (36%), Positives = 77/151 (50%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LI V L G S E + I + L++R+ TKEV DA
Sbjct: 5 ILIPQDVDESGKNYLQEKGYELRILQDSSIENICNNIGDCSGLLLRTVP-CTKEVFDAAP 63
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
LKV+GR G G DNID+ A +G+ V P ANA S E T L+L A+++V A L
Sbjct: 64 HLKVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKEL 123
Query: 422 KAGRWD-RALYTGSELAGKTLAILGLGRVGR 511
+ G ++ R G ++ GKTL I+G GR+G+
Sbjct: 124 RQGNYEIRNQMPGIDVFGKTLGIIGFGRIGK 154
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 87.0 bits (206), Expect = 2e-16
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 2/140 (1%)
Frame = +2
Query: 98 ELLNAYGIATT--TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 271
E LN G T T I KE+L + + +++ + Q+ KE++DA LK + + GA
Sbjct: 20 ENLNRLGNVTILDTDNGIEKEKLKQAVREVE-VIITAVVQIDKEIIDAAPNLKYIMKFGA 78
Query: 272 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 451
G DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+ L
Sbjct: 79 GYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE--LS 136
Query: 452 TGSELAGKTLAILGLGRVGR 511
G E+ K L I+G G +G+
Sbjct: 137 MGIEIFQKKLGIIGFGAIGQ 156
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 86.2 bits (204), Expect = 4e-16
Identities = 40/111 (36%), Positives = 67/111 (60%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DA++VR ++T EV+ A LKV+ + G GVDNID+ +A +G+ V+ + G+N+ + E
Sbjct: 58 DAMMVRQG-RITDEVIGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAE 116
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
L L+L + + P + A+K G W + + G + G L ++G G +GRE
Sbjct: 117 HAIALALMLVKEIQPLNAAVKGGAWPKPTFIGKDFQGAMLGLVGYGGIGRE 167
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 85.8 bits (203), Expect = 5e-16
Identities = 43/118 (36%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
Frame = +2
Query: 161 LMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 340
L+ + D ++VR+ TQV + LDA +L+V+G G G+DNID+ + +G+ V A GA
Sbjct: 39 LVAVARADGVIVRNRTQVDRPFLDAASRLRVIGLLGTGLDNIDMAACAARGISVHPATGA 98
Query: 341 NALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGR 511
N S E T L+L R ++ ++ G W R L G E+AG+ L + G G V +
Sbjct: 99 NTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGEGGEIAGRKLGLYGCGAVAQ 156
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 85.4 bits (202), Expect = 7e-16
Identities = 43/110 (39%), Positives = 65/110 (59%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DA++VR ++ +++ A LKVV + GAG ++ID+ +A GV V+ A GANA S E
Sbjct: 49 DAIIVRLVERIDADLMKASPNLKVVAKHGAGTNDIDLAAAKALGVPVLAAVGANAHSVAE 108
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
LML L + V ++ G WD+ Y G EL G+ L ++G+G +GR
Sbjct: 109 HAFMLMLALIKDVRNQDAYVRGGGWDKKGYRGRELRGRVLGLVGIGMIGR 158
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 85.4 bits (202), Expect = 7e-16
Identities = 40/101 (39%), Positives = 67/101 (66%)
Frame = +2
Query: 209 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
+++ +VL+ +LK + R G GVD+IDV++A + G+ V+ APGAN+ ELT L+L
Sbjct: 72 RLSGQVLEDLTRLKAISRNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAG 131
Query: 389 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+R + LK+G+W+R G+E++GK L ++G G++GR
Sbjct: 132 SRSIPWHDAQLKSGQWNRR--PGNEVSGKVLGLIGCGQIGR 170
>UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=3; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 396
Score = 85.4 bits (202), Expect = 7e-16
Identities = 51/151 (33%), Positives = 79/151 (52%), Gaps = 1/151 (0%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 241
+LI D + K E+L A G I++ L EI +++ L+VRS V ++A
Sbjct: 4 ILIADSLSPKAVEMLKAAGHEVRMDPSITQASLANEISDYNVLIVRSKV-VNAAAIEAAK 62
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
L ++ RAGAGV+ IDV++A KGV V N PG N + EL ++ R + + L
Sbjct: 63 GLNLIIRAGAGVNTIDVNAASAKGVLVCNTPGMNNDAVAELAFGHIVCCDRCITTNTAHL 122
Query: 422 KAGRWDRALYTGSE-LAGKTLAILGLGRVGR 511
+ G W + L+ E L +TL I+G G + +
Sbjct: 123 RNGEWRKKLFLTCEGLRDRTLGIVGRGNIAK 153
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 85.4 bits (202), Expect = 7e-16
Identities = 49/162 (30%), Positives = 83/162 (51%), Gaps = 1/162 (0%)
Frame = +2
Query: 32 KPRMVVDIKSVLIVDGVGAKCAELLNAYGIATTT-KAKISKEELLMEIPNHDALVVRSAT 208
KP D+K +L+++ V + G K+ + +EEL+ +I + A+ +RS T
Sbjct: 52 KPFSTGDMK-ILLLENVNQTAITIFEEQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKT 110
Query: 209 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
++T VL L +G G + +D+D A +G+ V N+P +N+ S EL ++ L
Sbjct: 111 RLTSNVLQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISL 170
Query: 389 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
AR + S L G W++ E+ GKTL I+G G +G +
Sbjct: 171 ARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQ 212
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 85.0 bits (201), Expect = 9e-16
Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Frame = +2
Query: 56 KSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 229
K V++V + + E+L + + K + + + + + ++ ++ V+
Sbjct: 144 KPVVLVTAADLAPQALEMLAQFDVVFAGKQPTEDDIVALCVKHKPVAIIVRYGKINARVM 203
Query: 230 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 409
DA L+V+ + G+G+D ID D+A +G+ V A GANA + E L+L A+ V
Sbjct: 204 DAAENLQVISKHGSGIDVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQL 263
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
++ G WD+A + EL G+TL ++GLG +GR
Sbjct: 264 DMRMREGHWDKATHKSVELDGRTLGLVGLGAIGR 297
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 84.2 bits (199), Expect = 2e-15
Identities = 49/153 (32%), Positives = 81/153 (52%), Gaps = 2/153 (1%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTTKAKISKE-ELLMEIPNHDALV-VRSATQVTKEVLDA 235
+L+++G+ A A G T+ K + E + L E +V +RS TQ+T+EVL+
Sbjct: 14 ILLLEGIHESAAAHFAAEGYTEVTRVKGALEGDALKEALQGVHMVGIRSRTQLTREVLEG 73
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
+L +G G + +D+++A G+ V NAP +N S EL +++L R + S
Sbjct: 74 ADRLMAIGCFCIGTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSE 133
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
A G WD++ E+ GKTL I+G G +G +
Sbjct: 134 ACHKGGWDKSATNAWEVRGKTLGIVGYGSIGSQ 166
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 84.2 bits (199), Expect = 2e-15
Identities = 39/126 (30%), Positives = 73/126 (57%), Gaps = 3/126 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+SKEE++ DA+V + + KE + + K K++ G +NID+++A ++G+ V
Sbjct: 32 LSKEEMIKRAEYADAIVTQLRDPIDKEFIYSLKKAKIIANYAVGYNNIDIEAAKERGIYV 91
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 493
N PG + ++ L+L +AR +V + ++ G+ W L+ G +L GKTL ++G
Sbjct: 92 TNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIG 151
Query: 494 LGRVGR 511
+GR+G+
Sbjct: 152 MGRIGQ 157
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 83.8 bits (198), Expect = 2e-15
Identities = 45/151 (29%), Positives = 73/151 (48%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
+ VL +D LL G + +++ L + +V+RS ++ E L +
Sbjct: 4 RKVLFIDSAHPSLTLLLQELGFTCDYFPEYKRDDYLKIASQYLGVVIRSKIKIDAEFLSS 63
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
+L+ + R GAG++NID+ SA K V +NAP N + E ++L L ++ A
Sbjct: 64 ATQLRFIARVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADA 123
Query: 416 ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
++ G W R G EL GKT+ I+G G G
Sbjct: 124 EVRKGIWLREQNRGIELGGKTVGIIGYGNTG 154
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 83.4 bits (197), Expect = 3e-15
Identities = 48/118 (40%), Positives = 68/118 (57%), Gaps = 3/118 (2%)
Frame = +2
Query: 167 EIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 343
EI N DA+ +R ++ E++ A KL++V R GAG DN+D +A + GV V N PGAN
Sbjct: 37 EIQNEVDAVFLRGG-HISAEMIAASPKLRIVARHGAGYDNVDYKAAAELGVWVTNTPGAN 95
Query: 344 ALSACELTCTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGR 511
S E L+L ++R V A+ + W DR TG EL G+TL ++G G +GR
Sbjct: 96 RRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSLTGIELEGRTLGLIGFGDIGR 153
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 83.4 bits (197), Expect = 3e-15
Identities = 51/142 (35%), Positives = 72/142 (50%), Gaps = 1/142 (0%)
Frame = +2
Query: 83 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 262
G A +L+A T A E + + DAL+V + TQVT EV++A LKVVGR
Sbjct: 15 GETRAAVLDAVDATVETIAAKEPEAVARAVDGADALIVDAGTQVTAEVIEAADSLKVVGR 74
Query: 263 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 442
AG G+DNI V +A GV V+N P + T LML R + ++K G W
Sbjct: 75 AGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKRGEWKW 134
Query: 443 AL-YTGSELAGKTLAILGLGRV 505
A+ LAG T+ ++ G++
Sbjct: 135 AVGQPIRRLAGSTVGLVAFGKL 156
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/101 (41%), Positives = 62/101 (61%)
Frame = +2
Query: 209 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
+V E L+A LK++ + G GVD+ID+ +A +G+ V NAPG NA S +L ML L
Sbjct: 61 KVYAEDLEAAPNLKLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSL 120
Query: 389 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
AR +V A + G W + G ++ GKTL +LGLG++G+
Sbjct: 121 ARQIVSADKRTRDGFWGTVM--GKDVYGKTLGVLGLGQIGK 159
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/131 (32%), Positives = 72/131 (54%)
Frame = +2
Query: 119 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDS 298
I + + KI+ EL +I N D L+ ++T+EV+ LK++ R G G+D ++ +
Sbjct: 29 ILNSHERKITTRELASDIGNSDVLIA-GTERITEEVIKNAPNLKLISRVGVGLDGVNFEL 87
Query: 299 AGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKT 478
K G+ V P A ++ EL ++L L+R + ++ G WDR Y G+ L GKT
Sbjct: 88 CNKYGIKVTYTPDAPTMAVAELCVGIILDLSRKISYTDRNVRKGVWDR--YMGNLLYGKT 145
Query: 479 LAILGLGRVGR 511
+ I G+GR+G+
Sbjct: 146 VGIFGMGRIGK 156
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 82.6 bits (195), Expect = 5e-15
Identities = 47/112 (41%), Positives = 69/112 (61%), Gaps = 1/112 (0%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DAL+V VT E+++ LK++ + G GVDNID+++A KKG+ V GAN+LS E
Sbjct: 44 DALIV-GTHPVTAEMVENS-SLKIIAKHGVGVDNIDLEAATKKGIPVTITAGANSLSVAE 101
Query: 362 LTCTLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
LT + L+R +V A L RW+ + G E++GKTL ++G G +GRE
Sbjct: 102 LTIAFIFALSRGLVWAHNKLFLERRWEGTV--GQEVSGKTLGVVGFGSIGRE 151
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 82.6 bits (195), Expect = 5e-15
Identities = 42/93 (45%), Positives = 55/93 (59%)
Frame = +2
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
AG L+ + R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV +
Sbjct: 65 AGDALRAICRPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASD 124
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
L+ W A G E+ GKTL I+GLGR+GR
Sbjct: 125 RVLRTEGWRAARLRGIEVRGKTLGIVGLGRIGR 157
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 81.8 bits (193), Expect = 8e-15
Identities = 44/154 (28%), Positives = 83/154 (53%), Gaps = 1/154 (0%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
K V + D + A ++L G+ + E++ E A+++ + +++DA
Sbjct: 3 KQVFLPDDIPAVGKKILEEAGLEVVVGSGRDHEKMKAEGVEASAVLI-GTQKFDADIMDA 61
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
LKV+ R G G D +DVD+A ++G+ V+N P A + S E + +L +++++ S
Sbjct: 62 MPNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSK 121
Query: 416 ALKAGRWD-RALYTGSELAGKTLAILGLGRVGRE 514
A+ W+ R + G ++ GKT+ ILG GR+G++
Sbjct: 122 AIHDDNWNYRKAHPGRDIEGKTVGILGFGRIGQQ 155
>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
Alphaproteobacteria|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 166
Score = 81.8 bits (193), Expect = 8e-15
Identities = 51/118 (43%), Positives = 60/118 (50%)
Frame = -1
Query: 501 LPRPRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALI 322
+P P RVL SS+P+ SHLPA+ EA WRA NI S + L G I
Sbjct: 1 MPAPMTPRVLLVSSVPMNLDFSHLPAWVEAEASGIWRATANIIAMACSAVVIILPNGVFI 60
Query: 321 TPTPFLPAESTSMLSTPAPARPTTFSFTPASNTSLVT*VAERTTRASWLGISIRSSSL 148
T TP L A S SMLS P PAR T + + VT VAER R S+ I+ S SL
Sbjct: 61 TITPRLEAASLSMLSVPMPARAMTLRLSALARIFSVTLVAERMARPSYWPITSASLSL 118
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 81.4 bits (192), Expect = 1e-14
Identities = 51/131 (38%), Positives = 73/131 (55%), Gaps = 11/131 (8%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
K LL E DA++VRS K++ D +++V+GRAG GV+NI V GV V+N
Sbjct: 23 KYTLLTECEEPDAILVRSCNLHDKKIAD---RVQVIGRAGVGVNNIPVRPLTLSGVPVLN 79
Query: 329 APGANALSACELTCTLMLVLARHVVPA-----------STALKAGRWDRALYTGSELAGK 475
PGANA + EL T +L+ +RH+ PA T ++ ++G EL GK
Sbjct: 80 TPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITHQVEKNKKRFSGFELPGK 139
Query: 476 TLAILGLGRVG 508
TL I+GLG++G
Sbjct: 140 TLGIIGLGQIG 150
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 81.4 bits (192), Expect = 1e-14
Identities = 49/143 (34%), Positives = 80/143 (55%), Gaps = 1/143 (0%)
Frame = +2
Query: 83 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 262
G K E NA +A T + + +L E+ + + L++R + + +E + LKV+GR
Sbjct: 15 GMKVLEDANAQ-VAITNDG--NPKIMLPELLDAEGLIIRIGS-IDRETMLQAKNLKVIGR 70
Query: 263 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD- 439
G GVD++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G +
Sbjct: 71 PGVGVDDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAI 130
Query: 440 RALYTGSELAGKTLAILGLGRVG 508
R+ Y EL KTLA++G GR+G
Sbjct: 131 RSSYKAYELNHKTLALIGYGRIG 153
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 81.4 bits (192), Expect = 1e-14
Identities = 48/139 (34%), Positives = 80/139 (57%)
Frame = +2
Query: 92 CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 271
C +LN +G T EE++ + DAL+V + +V +V+ +LK++ + G
Sbjct: 29 CEVVLNPFGRPFTN------EEIIRYASDADALIVGN-DKVPGDVIKKCKRLKIIAKHGV 81
Query: 272 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 451
GVD+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W + +
Sbjct: 82 GVDSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV- 140
Query: 452 TGSELAGKTLAILGLGRVG 508
G L+ KT+ I+G+G +G
Sbjct: 141 -GISLSKKTIGIIGVGTIG 158
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 81.4 bits (192), Expect = 1e-14
Identities = 43/115 (37%), Positives = 61/115 (53%), Gaps = 1/115 (0%)
Frame = +2
Query: 170 IPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 346
+P A ++ + +D AG L + R G GVDNID+ +A ++G+ VIN P
Sbjct: 44 LPGSAAAIISAMINADGAWMDRAGPTLMAIARPGIGVDNIDLAAATERGILVINTPDGPT 103
Query: 347 LSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
S E L+L LA+ VV A + W A G E+ GKTL ++GLGR+GR
Sbjct: 104 ESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRGVEVRGKTLGVVGLGRIGR 158
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 81.4 bits (192), Expect = 1e-14
Identities = 41/132 (31%), Positives = 71/132 (53%), Gaps = 5/132 (3%)
Frame = +2
Query: 131 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 310
T+ + +EE+L ++ + DA++ + E++ G KLKV+ GAG D +DV +A ++
Sbjct: 7 TEDYMPREEVLHKVTDVDAIICHGKDKADAELVAKGSKLKVISNFGAGYDTVDVKAATER 66
Query: 311 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-----ALYTGSELAGK 475
+ V N PGA + ++ L+L R A L+ G W+R + G+ GK
Sbjct: 67 NIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGK 126
Query: 476 TLAILGLGRVGR 511
TL I+G+G +G+
Sbjct: 127 TLGIIGMGNIGK 138
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 81.0 bits (191), Expect = 1e-14
Identities = 40/124 (32%), Positives = 71/124 (57%)
Frame = +2
Query: 140 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
K++++E++ + N ++ +T+ VL + L+V+ R G G+DN+D+++A + +
Sbjct: 37 KLTEDEIITLLGNDTVALLAGVEPLTEHVLTSASALRVIARCGTGMDNVDLEAARRLNIQ 96
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 499
V N P A A + ELT LML R + +++ G W R+ G LA +T+ I+GLG
Sbjct: 97 VSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QGRLLAARTVGIVGLG 154
Query: 500 RVGR 511
+GR
Sbjct: 155 HIGR 158
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 81.0 bits (191), Expect = 1e-14
Identities = 53/142 (37%), Positives = 71/142 (50%), Gaps = 4/142 (2%)
Frame = +2
Query: 98 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 277
+LL A GI A + L I DA++VR Q+ E++D +L V+ G G
Sbjct: 16 QLLRAAGITVIEPAGPGLDALRQVIAGADAVLVRD--QLPAELIDMAPRLCVIANHGTGT 73
Query: 278 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 445
D I V A G+ V+ P AN S E LMLV AR V A A + G W ++
Sbjct: 74 DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQP 133
Query: 446 LYTGSELAGKTLAILGLGRVGR 511
+Y+ L GKTL ++GLGR GR
Sbjct: 134 MYS---LYGKTLGVIGLGRTGR 152
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/111 (38%), Positives = 65/111 (58%), Gaps = 1/111 (0%)
Frame = +2
Query: 182 DALVVRSATQ-VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 358
D + V + T+ +T V+DA LKV+ R G G+DN+D+++A +G+ V N P +
Sbjct: 48 DCVAVAAGTEPLTARVMDALPGLKVISRCGTGMDNVDMEAARARGIAVRNTPDGPTQAVA 107
Query: 359 ELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
ELT L L L R V L++G W + + G+ L GK L I+G+GR+GR
Sbjct: 108 ELTLGLALDLMRQVSRMDRELRSGVWKKRM--GNLLGGKRLGIVGMGRIGR 156
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 80.6 bits (190), Expect = 2e-14
Identities = 45/124 (36%), Positives = 72/124 (58%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
IS+ ++E A +V + ++ VL LK++ + G GVDNIDVD+A K GV V
Sbjct: 35 ISQSAFVLEARGAQAAIV-AFNEIHDAVLAQLPDLKIIAKHGVGVDNIDVDAAKKHGVTV 93
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
N P AN + + +L+L LAR + + K G+W +L+ G+++ +TL I+GLG
Sbjct: 94 TNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-GADVYQQTLGIIGLGA 151
Query: 503 VGRE 514
+G+E
Sbjct: 152 IGKE 155
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 80.2 bits (189), Expect = 3e-14
Identities = 39/106 (36%), Positives = 59/106 (55%)
Frame = +2
Query: 194 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 373
+ ++ V +++L LKV+ RAG G DN+D+D+A + G+ V N PG N + EL
Sbjct: 54 IAASEPVARDMLATSPMLKVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALA 113
Query: 374 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
LML AR + + G W R G+EL GK+L ++G G G+
Sbjct: 114 LMLACARRLNTVLAGVDDGGWPRE--AGTELRGKSLGVIGYGPSGK 157
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 80.2 bits (189), Expect = 3e-14
Identities = 43/125 (34%), Positives = 71/125 (56%), Gaps = 3/125 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+ ++EL +I DA++ + + E++ G LKV+G+ AG +NID+D+A + GV V
Sbjct: 31 MDRQELSRQIATADAILTSLSDPLDAEMIGQGKNLKVIGQCAAGFNNIDLDAAKQAGVVV 90
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILG 493
+ PG + +L TL+L + R A ++AG R+D G+ L G TL I+G
Sbjct: 91 TSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIVG 150
Query: 494 LGRVG 508
LG++G
Sbjct: 151 LGQIG 155
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 80.2 bits (189), Expect = 3e-14
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 1/137 (0%)
Frame = +2
Query: 104 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN 283
LN GI T + E ++ E+ + DA++ R + E LDA LK++ G+G +
Sbjct: 18 LNNAGIRTRYATAPTMEAVIREVGDADAVITRDLG-FSAEALDAAPNLKIISCHGSGTNR 76
Query: 284 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGS 460
I +A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R G
Sbjct: 77 IAKAAAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGM 136
Query: 461 ELAGKTLAILGLGRVGR 511
EL +TL ++G G + R
Sbjct: 137 ELHTRTLGLVGFGAIAR 153
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 80.2 bits (189), Expect = 3e-14
Identities = 45/124 (36%), Positives = 74/124 (59%)
Frame = +2
Query: 140 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
+ SKEEL+ +I + +A++ + +++EV+D LKV+ + G G+DNIDVD A K +
Sbjct: 37 RYSKEELIEKIKDANAIITGN-DPLSREVIDQAKNLKVISKYGVGLDNIDVDYANSKDIV 95
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 499
V A AN++S E+T +ML +R V + + G+ R + G EL K L ++GLG
Sbjct: 96 VHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--GYELYQKNLGLIGLG 153
Query: 500 RVGR 511
+G+
Sbjct: 154 AIGQ 157
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 80.2 bits (189), Expect = 3e-14
Identities = 41/109 (37%), Positives = 63/109 (57%)
Frame = +2
Query: 185 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 364
ALV+R + V+ VL A L++V + GAGVD++D+++A +GV V A ANA + E
Sbjct: 55 ALVLRGSKPVSAAVLRAAPALRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEH 114
Query: 365 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
LML L R + ++AG W + + G + G T+ I+G G +GR
Sbjct: 115 ALALMLALVRQLPQLDQQVRAGGWAGSNWQGRDFRGSTVGIVGYGAIGR 163
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 79.8 bits (188), Expect = 3e-14
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 1/152 (0%)
Frame = +2
Query: 56 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
K +L+ + + E L + G T + + ++ ++ +IP D ++VR + ++ V DA
Sbjct: 23 KRILLPQELMPEGREYLESRGYQLVTGSGMDEDHVIHDIPECDGIIVR-LSPMSARVFDA 81
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
KLKV+ R G+G D +D+ +A K GV V+NAP AN+ S EL ML +R+
Sbjct: 82 AKKLKVLVRHGSGYDTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQ 141
Query: 416 ALKAGRWDRALYT-GSELAGKTLAILGLGRVG 508
+ + L T SE+A K L ++G+G +G
Sbjct: 142 TMLVDYYKAKLDTPKSEIACKKLGLIGVGNIG 173
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 79.4 bits (187), Expect = 4e-14
Identities = 43/156 (27%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Frame = +2
Query: 53 IKSVLIVDGVGAKCAELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVL 229
+ L+++ + + L G ++ + +++L+ + D L +RS T+VT+ V+
Sbjct: 21 VMKALLLENIHDEAVRTLKKAGYEVERVSEALDEDDLISALDGVDLLGIRSRTRVTRRVV 80
Query: 230 DA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 406
+A G KL VG G + +D+D+ + GV NAP +N S EL ++ LAR +
Sbjct: 81 EACGDKLHAVGAFCIGTNQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGD 140
Query: 407 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
+T + G W ++ E+ G+ L I+G G +G++
Sbjct: 141 RNTQMHNGVWRKSAIGSHEIRGRRLGIIGYGNIGQQ 176
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 79.4 bits (187), Expect = 4e-14
Identities = 43/122 (35%), Positives = 69/122 (56%), Gaps = 2/122 (1%)
Frame = +2
Query: 152 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 331
E+ L+ + + A+++ + K DA LK++ R G G DNI V+SA K GV V N
Sbjct: 35 EKKLLSLASDAAVIIMTDMAFDKNWFDALPNLKLIARRGVGYDNIPVESATKHGVWVTNT 94
Query: 332 PGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALYTGSELAGKTLAILGLGRV 505
PGANA++ EL TL+L + R V A+ +++ G A G L+GK + ++G G++
Sbjct: 95 PGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASLMGHNLSGKIIGLIGYGQI 154
Query: 506 GR 511
+
Sbjct: 155 AQ 156
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 79.4 bits (187), Expect = 4e-14
Identities = 44/127 (34%), Positives = 75/127 (59%)
Frame = +2
Query: 131 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 310
T+A+++ E L P DA++ R+ + +++ L+V+ R G G +N+D++SA ++
Sbjct: 34 TEAELA--ESLRSTP-FDAVISRTLA-LPAMMIETAPALRVISRHGVGYNNVDIESATRR 89
Query: 311 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAIL 490
GV V+ A GAN S EL L L +AR + +++A +W+R+ Y G + AGKT I+
Sbjct: 90 GVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-GLQFAGKTAGIV 148
Query: 491 GLGRVGR 511
G +GR
Sbjct: 149 AFGAIGR 155
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 79.4 bits (187), Expect = 4e-14
Identities = 39/101 (38%), Positives = 64/101 (63%), Gaps = 1/101 (0%)
Frame = +2
Query: 212 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 391
V+ +V+ A L+ + R G G+DN+ + ++G+G++ A GANA+ EL+ LML
Sbjct: 60 VSDKVIAAADSLRAISRNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAAL 119
Query: 392 RHVVPASTA-LKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
RH +PA TA ++AG W R+ G E+A +T+ I+G G +G+
Sbjct: 120 RH-IPAETAGIRAGGWPRS--RGREIAERTVGIIGCGAIGK 157
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 79.0 bits (186), Expect = 6e-14
Identities = 41/126 (32%), Positives = 68/126 (53%), Gaps = 3/126 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+S+E L + + A V+ + + +EV +LKV+ G DNID+ A K GV V
Sbjct: 34 MSRESFLANVEDATACVITLSEHIDEEVFLRAQQLKVIANMAVGFDNIDISLAKKHGVVV 93
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILG 493
N P + EL TLML +AR ++ A++ ++ G+W L +G ++ G T+ I G
Sbjct: 94 TNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYLLSGKDVYGATVGIFG 153
Query: 494 LGRVGR 511
+G +G+
Sbjct: 154 MGDIGK 159
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 79.0 bits (186), Expect = 6e-14
Identities = 42/109 (38%), Positives = 61/109 (55%)
Frame = +2
Query: 185 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 364
AL +RS+++ T+ V A KL++V G G D++D+ +A + GV V N PG A S E
Sbjct: 52 ALNIRSSSRFTERVFAACPKLRMVSIWGTGTDHVDLAAAARHGVTVANTPGVAARSIAEH 111
Query: 365 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
T L+ +AR + A + G W+R EL GKT ++G G VGR
Sbjct: 112 TLALLFAVARQIPHMDAATRRGAWERG--QSMELYGKTCGVIGYGAVGR 158
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 79.0 bits (186), Expect = 6e-14
Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 2/141 (1%)
Frame = +2
Query: 98 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 277
E + G+ T ++ +E + + D +V + ++T+E++ KLK++ + G GV
Sbjct: 19 ESIKPSGVTVTYWYTLNDKEKEQALNSADYFLV-ALYKITQELIQKAPKLKMIQKTGVGV 77
Query: 278 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 457
DNID+ +A G+ V N PG NA S ELT +++ L R + K G W +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137
Query: 458 S--ELAGKTLAILGLGRVGRE 514
S E+ GKT I+G G +GRE
Sbjct: 138 SSYEVKGKTHGIIGFGNIGRE 158
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 78.6 bits (185), Expect = 8e-14
Identities = 47/154 (30%), Positives = 77/154 (50%), Gaps = 2/154 (1%)
Frame = +2
Query: 59 SVLIVDGVGAKCAELLNAYGIATTTKAKISKE--ELLMEIPNHDALVVRSATQVTKEVLD 232
+ L+++ V L G T + S + +L EI + L +RS T V +LD
Sbjct: 8 TALLLENVHPDADNALQTAGPVTVKRLSGSPDRAQLESEIASASVLGIRSRTHVDAALLD 67
Query: 233 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 412
A +L+ VG G + +D+ +A ++GV V NAP AN S ELT +++L R +
Sbjct: 68 AAKELQAVGCFCIGTNQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKM 127
Query: 413 TALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
A++ G W + +E+ K L I+G G +G +
Sbjct: 128 FAIQRGEWLKTADGANEVRKKKLGIIGYGNIGAQ 161
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 78.2 bits (184), Expect = 1e-13
Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 1/171 (0%)
Frame = +2
Query: 5 SRLNNDSTTKPRMVVDIKSVLIVDGVGAKCAELLNAYGI-ATTTKAKISKEELLMEIPNH 181
S L DSTT + ++ SVL+++ + + + K ++ EL + H
Sbjct: 11 SGLRYDSTTT---LGNMTSVLLLENIHDSASRHFADTNVDIERRKGALAGAELRRALQQH 67
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
+ +RSAT + ++ +DA L +G G +D+ +A G+ V NAP +N S E
Sbjct: 68 QLIGIRSATHLLRDEIDAARHLLAIGCFCIGTSQVDLPAAAHHGIPVFNAPFSNTRSVAE 127
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
L ++L R V S AG W + E GKT+AI+G G +G +
Sbjct: 128 LVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFEARGKTIAIVGYGNIGAQ 178
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 78.2 bits (184), Expect = 1e-13
Identities = 42/101 (41%), Positives = 61/101 (60%)
Frame = +2
Query: 212 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 391
VT++VL A +LKV+ R G G D +DVD+A G V A GAN + + T LML +
Sbjct: 94 VTRDVLAAHPQLKVIARRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVL 153
Query: 392 RHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
R + + A+ G W R L G++L GKT+ ++G GR+GR+
Sbjct: 154 RRLKASQAAIARGDW-RVL-VGADLTGKTVGLIGFGRIGRQ 192
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 77.8 bits (183), Expect = 1e-13
Identities = 43/126 (34%), Positives = 70/126 (55%), Gaps = 4/126 (3%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
S+EEL + L+ + ++ E++D AG +L VV G +NIDVD+A +GV V
Sbjct: 120 SREELCRLVKGRHGLLTMLSDRIDGELMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVV 179
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 493
N P + +L +L+ +RHV+PA ++ G W+ + G E + KTL I+G
Sbjct: 180 GNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTGWLGVEPSDKTLGIVG 239
Query: 494 LGRVGR 511
+GR+G+
Sbjct: 240 MGRIGK 245
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 77.8 bits (183), Expect = 1e-13
Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 244
++V G+ + L T A K+ L + + DAL+ V +E+LDAG K
Sbjct: 12 VLVAGLAVRQLPELEKVCEVTFAPAGAGKDWYLANLGDFDALIT-GKLPVDQELLDAGKK 70
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
LK+V G G D+IDVD A +G+ V N P + E+ TL+L L+R + + ++
Sbjct: 71 LKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAEMAFTLLLALSRKLALYNQEMR 130
Query: 425 AGRW-DRALY--TGSELAGKTLAILGLGRVGR 511
+ D L G GKTL I G+GR+G+
Sbjct: 131 QENFLDTGLLENQGQSPVGKTLGIFGMGRIGK 162
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 77.8 bits (183), Expect = 1e-13
Identities = 39/128 (30%), Positives = 71/128 (55%), Gaps = 6/128 (4%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
S+EEL IP D +++ T++TK++L+ +LKV+ AG D++DV+ A K+G+ V
Sbjct: 32 SEEELKEIIPELDGIIIAPVTRITKDILERAERLKVISCQSAGYDHVDVEEATKRGIYVT 91
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE------LAGKTLAI 487
G + + E L++ L R + A + ++ G+W+ + E L GK + I
Sbjct: 92 KVSGLLSEAVAEFALGLLISLMRKIHYADSFIREGKWESHTFVWREFKEVETLYGKEVGI 151
Query: 488 LGLGRVGR 511
+G+G +G+
Sbjct: 152 VGMGAIGK 159
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 77.0 bits (181), Expect = 2e-13
Identities = 40/126 (31%), Positives = 68/126 (53%), Gaps = 3/126 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+ K ELL + L+ ++ EV+D LKV+ GVD++D+++A ++G+ V
Sbjct: 59 LPKAELLKRVEGAVGLIPTVEDRIDAEVMDRAKGLKVIACYSVGVDHVDLEAARERGIRV 118
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILG 493
+ PG + +LT L+L +AR VV + + G W L G +L G TL ++G
Sbjct: 119 THTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPELLLGLDLQGLTLGLVG 178
Query: 494 LGRVGR 511
+GR+G+
Sbjct: 179 MGRIGQ 184
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/118 (39%), Positives = 68/118 (57%), Gaps = 9/118 (7%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DA ++RS T E L + LKV+ RAGAGV+NI +D A G V N PG+NA + E
Sbjct: 31 DAYLIRSVNLHT-ETLPSS--LKVIVRAGAGVNNIPIDQATANGTAVFNTPGSNANAVKE 87
Query: 362 LTCTLMLVLARHVVPAST---------ALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
L L+++ +R+++ A+T + D+ + G EL GKTLA++GLG VG
Sbjct: 88 LIIGLLIMASRNLIAATTYSAQHTEADISQRTEHDKTQFNGIELTGKTLAVIGLGHVG 145
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 76.6 bits (180), Expect = 3e-13
Identities = 54/151 (35%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 244
LIV + L A GIA + + DA++ R A + AG +
Sbjct: 4 LIVQPIHEAGLAALRAAGIAPILCPAPDMATVARHMAGIDAVITRDAG-LDAAAFAAGDR 62
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
L+ V GAG D +D ++A +KGV V N PGANA S EL L L +AR + A AL+
Sbjct: 63 LRAVVVHGAGHDPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALR 122
Query: 425 AGRWD-RALYTGSELAGKTLAILGLGRVGRE 514
G+ R SEL G+T ++G G GRE
Sbjct: 123 EGKTGFRESARFSELRGRTALVVGWGASGRE 153
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 76.6 bits (180), Expect = 3e-13
Identities = 42/132 (31%), Positives = 68/132 (51%), Gaps = 1/132 (0%)
Frame = +2
Query: 119 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDS 298
I TT +IS++ I DAL++R+ +T +D +LK+V R G G D +DV +
Sbjct: 24 ITTTYIDEISEDSYTPHIAGADALLIRTQA-LTSPTIDRADRLKIVSRHGVGYDAVDVAA 82
Query: 299 AGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAGK 475
+G+ + AN+ S E C L+L + + A A++ G W R ++ G+
Sbjct: 83 LNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLESQDIRGR 142
Query: 476 TLAILGLGRVGR 511
L ILG GR+G+
Sbjct: 143 NLLILGFGRIGQ 154
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 76.6 bits (180), Expect = 3e-13
Identities = 42/108 (38%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Frame = +2
Query: 188 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 367
L VR Q+T +VLDA +L V +G GVDNID+ +A + GV V N PG E
Sbjct: 47 LAVRYPAQITADVLDAAPQLLAVLSSGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHA 106
Query: 368 CTLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGRVG 508
L++++ R + + G W++ L T EL G TL I+G G VG
Sbjct: 107 LGLLIMITRDLTAVARDAMTGAWEKRLTTRRVELTGGTLGIVGCGNVG 154
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/161 (29%), Positives = 86/161 (53%), Gaps = 5/161 (3%)
Frame = +2
Query: 44 VVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 223
VV I S +IV+ + + LN+ +++++ + + A+V R A +++ +
Sbjct: 4 VVGIDSSVIVEELDQEKVRELNSLAEIVYFNPYAPEDQIVSLLRDAIAIVDRKA-KISSK 62
Query: 224 VLDAGVKLKVVGRAGAGVDN--IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 397
++ LK++ R GAGVD +D+ +A ++ + + PG N+++ ELT L + L R
Sbjct: 63 IIRELRNLKLIARTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRK 122
Query: 398 VVPASTALKAGRWDRAL---YTGSELAGKTLAILGLGRVGR 511
V+P + ++KAG+W G EL GK ILG G +G+
Sbjct: 123 VIPLALSVKAGKWSELKPKDTMGHELEGKAWGILGFGNIGK 163
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 76.2 bits (179), Expect = 4e-13
Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 3/125 (2%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
++ +L I +D ++V KE++DA LKV+ G G D+ID+D A +KG+ V N
Sbjct: 39 RQWVLKNIAKYDGVIVAKMI-FDKEIIDAAKNLKVISTYGVGFDHIDIDYAREKGIVVTN 97
Query: 329 APGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRALYTGSELAGKTLAILGLG 499
P + EL T+++ AR + AL+ G + D G + GKTL ILG+G
Sbjct: 98 CPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYDSQGYTIEGKTLGILGMG 157
Query: 500 RVGRE 514
R+G++
Sbjct: 158 RIGQQ 162
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 76.2 bits (179), Expect = 4e-13
Identities = 34/89 (38%), Positives = 55/89 (61%)
Frame = +2
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
L++V GAG +N+DV +A ++G+ V +APG NA + + ++L LAR P + A++
Sbjct: 66 LEIVCAFGAGYENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALARGYAPLTGAVR 125
Query: 425 AGRWDRALYTGSELAGKTLAILGLGRVGR 511
AGRW + L G L ++G+GR+GR
Sbjct: 126 AGRWHASRAARPTLTGAALGVIGMGRIGR 154
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 76.2 bits (179), Expect = 4e-13
Identities = 40/107 (37%), Positives = 57/107 (53%)
Frame = +2
Query: 194 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 373
VRS T+V + +A +L VG G D ID++ A + GV V NAP +N S EL
Sbjct: 49 VRSKTKVRAPIFEAVPRLAAVGAFCIGTDQIDLEVAAQSGVAVFNAPFSNTRSVAELVIA 108
Query: 374 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++ L+R + S A GRW + E+ GKTL I+G G +G +
Sbjct: 109 EIVCLSRQLFERSWAAHEGRWRKDAKGAHEVRGKTLGIIGYGHIGSQ 155
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 75.8 bits (178), Expect = 6e-13
Identities = 41/126 (32%), Positives = 67/126 (53%), Gaps = 4/126 (3%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
I K EL+ I DA+ ++ +EVL A G KLKV+ GVD++D+ + + +
Sbjct: 410 IPKPELIKRIKEADAIFCLLTDKIDEEVLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIP 469
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAIL 490
+ PG + ELT L+L +R ++ A+ A+ G W TG +++G + I+
Sbjct: 470 IGYTPGVLTDATAELTMALLLATSRRLIEANRAIYRGEWKAWCPTWMTGPKISGSNIGIV 529
Query: 491 GLGRVG 508
GLGR+G
Sbjct: 530 GLGRIG 535
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 75.8 bits (178), Expect = 6e-13
Identities = 39/102 (38%), Positives = 62/102 (60%), Gaps = 1/102 (0%)
Frame = +2
Query: 212 VTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
+T V+D + +LKV+ + G G+D IDV A K + V+ PG N + E T L+L L
Sbjct: 58 ITAAVIDKSLPRLKVISKYGIGLDKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLAL 117
Query: 389 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++++ + + ++G W R TG EL KT+ I+GLGR+G+E
Sbjct: 118 EKNILFHTDSTRSGGWKRK--TGHELLAKTIGIVGLGRIGKE 157
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 75.4 bits (177), Expect = 7e-13
Identities = 42/122 (34%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
+K E+ I + VR T++ + + KLKV+ +G G D ID+ A K GV V+
Sbjct: 46 TKNEINQAIQEASGVFVRYPTKLDAQAIGLAKKLKVISTSGFGTDAIDISVATKHGVVVV 105
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGR 502
N PG + + E T ++L LA+ + + +K G + R +L GKTL I+GLGR
Sbjct: 106 NNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQPMQLEGKTLGIVGLGR 165
Query: 503 VG 508
+G
Sbjct: 166 IG 167
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 75.4 bits (177), Expect = 7e-13
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 2/124 (1%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+ KE L+ +ALV+ + KEVLDAG KLK+V A GVD+IDV+ A +KGV V
Sbjct: 40 VPKEVLIDAARRCEALVIFIGDVIDKEVLDAGEKLKIVSTASVGVDHIDVEYAKRKGVVV 99
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALYTGSELAGKTLAILGL 496
+ P + +L L++ + R + +++G D G L GK I+GL
Sbjct: 100 AHTPYVLVDAVADLAVGLLIAVTRKIALGDRLIRSGAADAVWGSLMGVNLRGKRAGIVGL 159
Query: 497 GRVG 508
G +G
Sbjct: 160 GNIG 163
>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 161
Score = 74.9 bits (176), Expect = 1e-12
Identities = 49/116 (42%), Positives = 56/116 (48%)
Frame = -1
Query: 498 PRPRMARVLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALIT 319
P+P + VLP S P+ R H P+ A WRA S A L GAL T
Sbjct: 3 PKPTIPTVLPKISTPLKEERFHSPSRRVASAAGIWRAVDRSRETACSQAEWMLEVGALAT 62
Query: 318 PTPFLPAESTSMLSTPAPARPTTFSFTPASNTSLVT*VAERTTRASWLGISIRSSS 151
TP A S LS P PARPT F A+ TS T VAERT RAS ++ SSS
Sbjct: 63 MTPASVAAGMSTLSRPTPARPTIFRLGAAAMTSASTLVAERTRRAS-ASLTASSSS 117
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 74.5 bits (175), Expect = 1e-12
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 4/126 (3%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
+++EEL+ + DA++ V E+LDA G + K++ G +N ++D+A K+GV
Sbjct: 35 LTREELMNAVKGRDAVITLLTDNVDAEILDAAGPQCKIIANYAVGFNNFNLDAATKRGVI 94
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAIL 490
+ N PG + L+L A+ + + ++ G+ W + G ++ GKTL I
Sbjct: 95 MTNTPGVLDKATATHAWALLLATAKRISESERYVREGKWKGWSPMTFIGQDVDGKTLGIA 154
Query: 491 GLGRVG 508
GLGR+G
Sbjct: 155 GLGRIG 160
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 74.1 bits (174), Expect = 2e-12
Identities = 40/121 (33%), Positives = 70/121 (57%)
Frame = +2
Query: 152 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 331
E L + D L++ + + KEV++A LK++ A G+D+I++++ K + V N+
Sbjct: 81 EVLKKRVETADVLILANMP-LKKEVIEAATNLKMISVAFTGIDHINMETCRKNNIMVCNS 139
Query: 332 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
G + S ELT L+L L R++VP + ++ G + Y+ +LAGKTL ++G G +G
Sbjct: 140 AGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQYDLAGKTLGVIGAGDIGT 198
Query: 512 E 514
E
Sbjct: 199 E 199
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/150 (34%), Positives = 76/150 (50%), Gaps = 4/150 (2%)
Frame = +2
Query: 77 GVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVV 256
G GA A + T +A L E H +++ VT E + A +L+++
Sbjct: 19 GAGAALASVFPGQARVTVVEATDEDPAALREA--H--VIITGLGPVTAEHIAAAPELQLI 74
Query: 257 GRAGAGVDNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAG 430
A G D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL
Sbjct: 75 QCASHGFDYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDA 134
Query: 431 RW--DRALYTGSELAGKTLAILGLGRVGRE 514
W R + +EL+GKTL I+GLG +G E
Sbjct: 135 DWALPRLQRSITELSGKTLGIVGLGHIGEE 164
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 74.1 bits (174), Expect = 2e-12
Identities = 36/113 (31%), Positives = 61/113 (53%)
Frame = +2
Query: 170 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 349
I + +AL+ RS +T ++ L+++ RAG+G+DN+D+D + ++ P A
Sbjct: 38 IRDREALIFRSGVNITAGIMACAPDLQLLIRAGSGLDNVDLDYLRNHDLKLVRIPQPGAR 97
Query: 350 SACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
+ EL +ML L+R ++ A L+ G W + G L K L I+GLG +G
Sbjct: 98 AVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRGHLLVNKQLGIVGLGNIG 150
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 74.1 bits (174), Expect = 2e-12
Identities = 39/135 (28%), Positives = 69/135 (51%)
Frame = +2
Query: 107 NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNI 286
N Y + + E+ ++EI +V + ++V+D L+ + R G G+D++
Sbjct: 25 NGYEVINNPFGRKLTEDEVIEIAKECVGIVAGVEPLNQKVMDNLPNLRCISRVGVGMDSV 84
Query: 287 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 466
D+D A +KG+ V N P S ELT + L L R V A +K G W + + G+ +
Sbjct: 85 DLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--GNLM 142
Query: 467 AGKTLAILGLGRVGR 511
K + ++GLG++G+
Sbjct: 143 YEKKVGLIGLGKIGK 157
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 74.1 bits (174), Expect = 2e-12
Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 3/146 (2%)
Frame = +2
Query: 83 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 262
G + A L + + +E L+ E LV +V ++DA L+ V
Sbjct: 13 GGELAPLRELFEVRGGAPRPPPRERLVEEAREAAVLVPTYIDRVDAALVDALPALRHVAS 72
Query: 263 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-- 436
G GV+++D+D+ ++GV V N PG + + L+L AR VV ++AG W
Sbjct: 73 YGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTE 132
Query: 437 -DRALYTGSELAGKTLAILGLGRVGR 511
D A G+E+ GKT+ ++G GR+G+
Sbjct: 133 VDPAWMLGTEVTGKTVGVVGFGRIGQ 158
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/110 (37%), Positives = 57/110 (51%)
Frame = +2
Query: 179 HDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 358
H V+ E+ DA K V+ R G G DNI++ A +KG+ N PGA S
Sbjct: 44 HAKYVIVGGAPYRNELYDAVPKGGVIARFGIGCDNINLPRAAEKGIYCTNTPGALEQSVA 103
Query: 359 ELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
E ++L+ AR + A+ + G W TG ELAGKTLA++G G +G
Sbjct: 104 ECAIGMILLAARQFIAAADDCRNGLWQP--QTGCELAGKTLAVIGCGAIG 151
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 74.1 bits (174), Expect = 2e-12
Identities = 49/127 (38%), Positives = 66/127 (51%), Gaps = 5/127 (3%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+++EL A VV +V E+LDA G L+VV G DNIDV +A GV V
Sbjct: 38 TRDELAAGFTGACAAVVTLTERVDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGVTV 97
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSEL-AGKTLAIL 490
N PG + + T L+L + R VV L++ R W + TG ++ AG TL IL
Sbjct: 98 TNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRMLTGLDVSAGATLGIL 157
Query: 491 GLGRVGR 511
G GR+GR
Sbjct: 158 GYGRIGR 164
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 73.7 bits (173), Expect = 2e-12
Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +2
Query: 164 MEIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 340
+EIP+ + L V ++++K+V+D+ LK++ G D+IDV A KG+ V N P
Sbjct: 38 VEIPDDIEILSVFIYSKISKDVIDSLPDLKLIATRSTGFDHIDVAYANSKGITVCNVPSY 97
Query: 341 NALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
S E LML LAR + ++ G + + G ELAGKTL ++G GR+G
Sbjct: 98 GEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRGIELAGKTLGVIGTGRIG 153
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 73.7 bits (173), Expect = 2e-12
Identities = 50/153 (32%), Positives = 81/153 (52%), Gaps = 12/153 (7%)
Frame = +2
Query: 86 AKCAELLNAYGIATTTKAKISKEELLM-EIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 262
A+ ++L I+ A++ + ++ ++ + DA++VRSA E+ + +GR
Sbjct: 2 AEARKILTLNAISARGLARLPEHYVVGGDLADPDAILVRSANMHEMEI---PTSVCAIGR 58
Query: 263 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA----------- 409
AGAG +NI V ++G+ V NAPGANA + EL ML+ AR++VPA
Sbjct: 59 AGAGTNNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTD 118
Query: 410 STALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
KA + + G EL G+TL ++GLG +G
Sbjct: 119 EAMHKATEAGKKQFAGMELPGRTLGVIGLGAIG 151
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 73.3 bits (172), Expect = 3e-12
Identities = 42/124 (33%), Positives = 66/124 (53%), Gaps = 3/124 (2%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
S +EL+ D L+ A +T+ + +A L++V + GVDNID+++A V V
Sbjct: 36 SVDELIALADGADVLLSVLADPITEALFEARPGLQMVSQYAVGVDNIDLEAAEAHDVAVT 95
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGL 496
+ PG + + L+L ARHV A ++ G RW+ G ELA KT+ I+G+
Sbjct: 96 HTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTHLMGMELARKTIGIVGM 155
Query: 497 GRVG 508
GR+G
Sbjct: 156 GRIG 159
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 73.3 bits (172), Expect = 3e-12
Identities = 46/136 (33%), Positives = 71/136 (52%), Gaps = 6/136 (4%)
Frame = +2
Query: 119 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKL---KVVGRAGAGVDNID 289
I T K +S E++L I + V+ T+ EVL + + K G +N+D
Sbjct: 42 ICTEKKTILSVEDILALIGDKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVD 101
Query: 290 VDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RALYTGS 460
V++A K GV V N PG + EL +L L AR +V A ++AGR+D L+ G+
Sbjct: 102 VNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGN 161
Query: 461 ELAGKTLAILGLGRVG 508
L G+T+ ++G GR+G
Sbjct: 162 LLKGQTVGVIGAGRIG 177
>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
domain; n=1; Symbiobacterium thermophilum|Rep:
Phosphoglycerate dehydrogenase, N-terminal domain -
Symbiobacterium thermophilum
Length = 140
Score = 72.9 bits (171), Expect = 4e-12
Identities = 37/97 (38%), Positives = 59/97 (60%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
S ++ E+ A++VR A T+E+++A L+V+ + G GVDNIDV +A ++G+ V+
Sbjct: 34 SPAAVIPELDGVQAIIVRLAP-CTREIIEAAPDLRVIAKHGVGVDNIDVAAATERGILVL 92
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 436
N P ANA+S E + LA+ VV A++ GRW
Sbjct: 93 NTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRW 129
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 72.9 bits (171), Expect = 4e-12
Identities = 39/110 (35%), Positives = 61/110 (55%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
+ L V T+V + VL +L++V AG D+ID+++ K+G+ V + P + S E
Sbjct: 51 EVLCVFVRTRVDESVLRMLPRLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAE 110
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
L+L + RH+ A + G + TG EL G+TL I+GLGR+GR
Sbjct: 111 HAFALLLGVTRHLTQAHERARQGSFAYRGLTGFELEGRTLGIVGLGRIGR 160
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 72.9 bits (171), Expect = 4e-12
Identities = 39/112 (34%), Positives = 63/112 (56%)
Frame = +2
Query: 176 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 355
N AL++RS+ +T E + + L +G+ G G++ ID D+ K+G+ ++N PGANA
Sbjct: 476 NARALLIRSS-YLTAEDIASCPNLVAIGKHGVGIEKIDQDACVKRGIKILNTPGANARDV 534
Query: 356 CELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
EL TL L +AR + +T + + G L KT+ I+G+G +GR
Sbjct: 535 AELVVTLALSVARGIRSITTRQMSKPVPKETCNGLTLYQKTIGIIGMGNIGR 586
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 72.9 bits (171), Expect = 4e-12
Identities = 40/104 (38%), Positives = 61/104 (58%), Gaps = 3/104 (2%)
Frame = +2
Query: 212 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 391
+T+E++ A K+K++ + G +NIDV++A K + V N G NALS E T L L
Sbjct: 60 ITEEMMRAMEKVKLIQQPSTGYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALL 119
Query: 392 RHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGRE 514
R ++ A ++ +GRW++ A EL GKT I+G+G GRE
Sbjct: 120 RRLIYAHNSVLSGRWEQDEMANLGVYELHGKTWGIIGMGAQGRE 163
>UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 325
Score = 72.5 bits (170), Expect = 5e-12
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 1/123 (0%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
S+E ++ + D ++VR ++ V++ V+DA + K V R G GVDNID+ +A + + V
Sbjct: 45 SEEAAILAVRGADVVLVRESS-VSRRVIDAMDRCKAVIRYGIGVDNIDMAAAAARRIAVA 103
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGR 502
N P T L L + R VV +++GRW + L G+TL ++G GR
Sbjct: 104 NVPDYGTDEVSTQTVALALAVVRQVVSHDREVRSGRWSTGVIKPMYRLRGRTLGLIGYGR 163
Query: 503 VGR 511
+ R
Sbjct: 164 IAR 166
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 72.5 bits (170), Expect = 5e-12
Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 3/126 (2%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
+KE LL I + D ++++S ++ KE + A LK+V AG G+D+I +D K+G+
Sbjct: 30 NKERLLEVIEDKDVVILKSRIELDKEAIFAAKHLKLVVMAGIGLDHICLDELKKRGIAWF 89
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGL 496
N P +A EL L L LAR + + L+ W R G L + I+G
Sbjct: 90 NIPDLSARGVAELVLGLTLSLARKICLGDSLLRNNEFKLWKRPELMGFNLQDRLFGIVGY 149
Query: 497 GRVGRE 514
G++G+E
Sbjct: 150 GKIGKE 155
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 72.5 bits (170), Expect = 5e-12
Identities = 41/128 (32%), Positives = 70/128 (54%), Gaps = 4/128 (3%)
Frame = +2
Query: 140 KISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGV 316
+I + + L++ DA L+ ++ +V DA KL++VG + AG++N++V A K+G+
Sbjct: 60 EIEEVDALIQSEGKDAELLAGLFVPISSKVFDAMPKLRIVGVSRAGLENVNVKEATKRGI 119
Query: 317 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS---ELAGKTLAI 487
V N G NA + + T LML R++ A ++K G W + EL GK + +
Sbjct: 120 LVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNSDWVPELKGKKVGL 179
Query: 488 LGLGRVGR 511
+G G +GR
Sbjct: 180 VGFGYIGR 187
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 72.1 bits (169), Expect = 7e-12
Identities = 42/127 (33%), Positives = 71/127 (55%), Gaps = 11/127 (8%)
Frame = +2
Query: 167 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 346
+I D ++VRS E+ ++ + +GRAGAG +NI V+ +G+ V N PGANA
Sbjct: 35 DITGPDVILVRSHNLHDMEIPESVI---AIGRAGAGTNNIPVNQMSARGIPVFNTPGANA 91
Query: 347 LSACELTCTLMLVLARHVVPASTALKAGRWD-----------RALYTGSELAGKTLAILG 493
+ EL ML+ +R+++PA ++ D + ++G EL G+TL ++G
Sbjct: 92 NAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNLQVEAGKKQFSGLELPGRTLGVIG 151
Query: 494 LGRVGRE 514
LG++GR+
Sbjct: 152 LGKIGRQ 158
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 72.1 bits (169), Expect = 7e-12
Identities = 41/158 (25%), Positives = 81/158 (51%), Gaps = 4/158 (2%)
Frame = +2
Query: 47 VDIKSVLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 223
+D K +L+ V + +L++ + + + S++ +L + +D ++ + KE
Sbjct: 1 MDKKKILVTGTVPKEGLRKLMDRFDVTYSEDRPFSRDYVLEHLSEYDGWLLMGQ-KGDKE 59
Query: 224 VLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 403
++DAG L+++ G D++D A +KG+ V N+P A + E+T L+L ++ +
Sbjct: 60 MIDAGENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLA 119
Query: 404 PASTALKAGRW---DRALYTGSELAGKTLAILGLGRVG 508
+ +++G W Y G L G TL I G+GR+G
Sbjct: 120 FYDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIG 157
>UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 204
Score = 72.1 bits (169), Expect = 7e-12
Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 11/146 (7%)
Frame = +2
Query: 104 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN 283
LN +A + E+ E+ + DA+++RS E+ ++ +GRAGAGV+N
Sbjct: 7 LNNISVAGLDRLPRDNYEVASEVAHPDAILLRSYKMHDMEIPKT---VQAIGRAGAGVNN 63
Query: 284 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA---STAL--------KAG 430
I VD +G+ V NAPGANA + EL ML+ AR++ + +T L K
Sbjct: 64 IPVDKMTARGISVFNAPGANANAVKELVVAGMLLAARNISQSWKFATGLEGDDAVISKNV 123
Query: 431 RWDRALYTGSELAGKTLAILGLGRVG 508
+ + G EL G+T+ ++GLG +G
Sbjct: 124 ESGKKNFVGFELPGRTMGVIGLGAIG 149
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 71.7 bits (168), Expect = 9e-12
Identities = 46/144 (31%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Frame = +2
Query: 89 KCAELLNAYGIATTTKAK---ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVG 259
K ELL+ GI + ++ EEL+ I ++V S + K+VL+ +LK +
Sbjct: 16 KPLELLSQAGIEYILNEQGYHLTDEELIQIIDGCAGIIVGSEP-LPKKVLETNPRLKTIA 74
Query: 260 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 439
G +DNIDV+ A +K + + N P A++ E T L+L L R + +++G W
Sbjct: 75 CCGKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWH 134
Query: 440 RALYTGSELAGKTLAILGLGRVGR 511
+ + G+ L GK + I+GLG+VG+
Sbjct: 135 KRI--GNLLHGKRVGIIGLGQVGK 156
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 71.7 bits (168), Expect = 9e-12
Identities = 41/109 (37%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Frame = +2
Query: 188 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 367
L+ RS QV +L+ L+V+ G G D I V A +G+ V + PG + CEL
Sbjct: 43 LITRSNYQVPLALLELLPALQVISTCGVGYDGIPVAYAQARGIAVTHTPGVLDDAVCELG 102
Query: 368 CTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGRVGR 511
L+L L R + + ++ GRW D A + LAGK + I+GLGR+GR
Sbjct: 103 VGLLLGLLRDIPASDRFVRDGRWSDSAYPLTTSLAGKAVGIVGLGRIGR 151
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 71.7 bits (168), Expect = 9e-12
Identities = 55/149 (36%), Positives = 80/149 (53%), Gaps = 23/149 (15%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 310
K K+S+E+L+ HDA +V S +T V+ A +LK++ A NIDV++A ++
Sbjct: 31 KPKLSEEQLIAL--GHDADFLVTSYDDITARVIKACPQLKLIACTRANPVNIDVNAATER 88
Query: 311 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-----------AGR-----WD- 439
G+ V+ PG N+ +A ELT LML LARH+ A +ALK AG WD
Sbjct: 89 GIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALKQRQFTATTPGNAGLKTDVVWDV 148
Query: 440 -----RALYTGSELAGKTLAILGLGRVGR 511
++ G EL KTL I+G G +G+
Sbjct: 149 TKDSPYEVFKGVELRNKTLGIVGYGSIGQ 177
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 71.7 bits (168), Expect = 9e-12
Identities = 39/124 (31%), Positives = 67/124 (54%), Gaps = 3/124 (2%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 325
+++EL+ D + + ++ +E+L+ +L+VV G +NID+ +A ++ V V
Sbjct: 34 TRDELVSGFQWADGALTMLSDKIDRELLEVAPRLRVVANYAVGYNNIDLTAANERHVVVT 93
Query: 326 NAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGL 496
N P A + +LT L+L +AR +V ++AG W G +L GKTL I+GL
Sbjct: 94 NTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAPEFLLGMDLHGKTLGIIGL 153
Query: 497 GRVG 508
G +G
Sbjct: 154 GEIG 157
>UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 421
Score = 71.7 bits (168), Expect = 9e-12
Identities = 41/144 (28%), Positives = 76/144 (52%), Gaps = 1/144 (0%)
Frame = +2
Query: 32 KPRMVVDIKSVLIVDGVGAKCAELLNAYGIATTT-KAKISKEELLMEIPNHDALVVRSAT 208
KP DIK +L+++ V ++L G K + +++L+ +I + + +RS T
Sbjct: 56 KPFNTTDIK-ILLLENVNQSGQDILREQGYQVEAHKTSLPEDQLIEKIRSVHVIGIRSKT 114
Query: 209 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
+++++VL L VVG G + +D++ A + G+ V N+P AN+ S EL ++ L
Sbjct: 115 RLSEKVLREAKNLLVVGCFCIGTNQVDLEYAARHGIAVFNSPFANSRSVAELVIAEIITL 174
Query: 389 ARHVVPASTALKAGRWDRALYTGS 460
AR + S + G W+++ T S
Sbjct: 175 ARQLGDRSNEMHRGTWNKSYTTTS 198
>UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Bacteroides fragilis
Length = 306
Score = 71.3 bits (167), Expect = 1e-11
Identities = 45/121 (37%), Positives = 68/121 (56%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
K +LL + + +A+++RS + EVLDA +LK+V RAGAG DN+D+++A GV V+N
Sbjct: 39 KAQLLDAVKDANAIIIRSDI-IDAEVLDAAKELKIVVRAGAGYDNVDLNAATAHGVCVMN 97
Query: 329 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
PG N+ + EL L++ R+ + +G+EL GK L I G VG
Sbjct: 98 TPGQNSNAVAELVFGLLVYAVRNFYNGT-------------SGTELMGKKLGIHAYGNVG 144
Query: 509 R 511
R
Sbjct: 145 R 145
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 71.3 bits (167), Expect = 1e-11
Identities = 38/100 (38%), Positives = 61/100 (61%), Gaps = 11/100 (11%)
Frame = +2
Query: 242 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 421
+L +GRAGAG +NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L
Sbjct: 52 ELLAIGRAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWL 111
Query: 422 KAGRW-DRAL----------YTGSELAGKTLAILGLGRVG 508
+ D+A+ ++GSE++GKTL ++GLG +G
Sbjct: 112 TGQKGNDKAIDVAVENGKKAFSGSEISGKTLGVIGLGNIG 151
>UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: Similar to
glycerate dehydrogenase - Staphylococcus haemolyticus
(strain JCSC1435)
Length = 179
Score = 70.9 bits (166), Expect = 2e-11
Identities = 33/91 (36%), Positives = 59/91 (64%)
Frame = +2
Query: 128 TTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGK 307
T + IS+E L+ +I + DAL+ +TQV+++V+++ KLK++ GAG +NID+ +A +
Sbjct: 28 TGETLISQELLIQKIQDADALITLLSTQVSRQVIESAPKLKIIANYGAGFNNIDIQAARE 87
Query: 308 KGVGVINAPGANALSACELTCTLMLVLARHV 400
+ V N P A+ + ELT ++L +AR +
Sbjct: 88 HHINVTNTPIASTNATAELTMGILLAVARRI 118
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 70.9 bits (166), Expect = 2e-11
Identities = 42/129 (32%), Positives = 63/129 (48%), Gaps = 4/129 (3%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
+ + + L+ I ALV + V+DA L+ + G D+IDV A +G
Sbjct: 65 RVPMPRRALIRAISGAHALVCFPYDVIDAGVMDAAPDLETIATYSVGYDHIDVAHARGRG 124
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL----YTGSELAGKTL 481
+ V P + +LT LML L R V ++AGRW + Y G+++ GKTL
Sbjct: 125 ITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRIIRAGRWRQIYGADDYLGTDVGGKTL 184
Query: 482 AILGLGRVG 508
ILG+GR+G
Sbjct: 185 GILGMGRIG 193
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/108 (35%), Positives = 60/108 (55%)
Frame = +2
Query: 191 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 370
V+ S T EVL +++VV R G G D+++V +A ++ + V PG S E T
Sbjct: 49 VICSTEPYTAEVLSR-TQVRVVSRVGVGYDSVNVPAATEQNIAVCRTPGTLHQSVVEHTI 107
Query: 371 TLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 514
++L + R+V+ + ++AG WDR G GKTL I+G G +G+E
Sbjct: 108 GMILAIYRNVISQNKQVRAGDWDRT--AGPRAYGKTLGIIGYGVIGKE 153
>UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5;
Burkholderiales|Rep: 2-hydroxyacid dehydrogenase -
Ralstonia solanacearum UW551
Length = 331
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 4/127 (3%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+S EL+ + ++ + ++ +LDA LK V G G +N+DV + +GV V
Sbjct: 34 LSPSELIERLQGKQGVMSTGSERIDAALLDACPGLKAVCNVGVGYNNVDVAACTARGVVV 93
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYT---GSELAGKTLAIL 490
N P + + LML AR + + ++ G W + +Y GS++ G TL IL
Sbjct: 94 TNTPDVLTQTTADFGFALMLATARRITESERFVRRGEWQKTGIYNQMLGSDIYGATLGIL 153
Query: 491 GLGRVGR 511
G+GR+G+
Sbjct: 154 GMGRIGQ 160
>UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3;
Mesorhizobium loti|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 341
Score = 70.1 bits (164), Expect = 3e-11
Identities = 41/126 (32%), Positives = 71/126 (56%), Gaps = 2/126 (1%)
Frame = +2
Query: 140 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
+ +++EL+ + AL+ S T++T+ V+ A L+ + + G GVD+ID+D+A + G+
Sbjct: 45 RFTEDELIAKAHGCIALMGASGTRITRRVMQALPDLRYISKYGIGVDSIDIDAATEHGIL 104
Query: 320 VINAPG-ANALSACELTCTLMLVLARHV-VPASTALKAGRWDRALYTGSELAGKTLAILG 493
V + P + E LML +A+ + ++ G W R L G+ L G T+ I+G
Sbjct: 105 VSSTPNDFQIFTVSEHAVALMLAVAKQLGTWTPEFMRRGGW-RGLTHGATLRGATVGIVG 163
Query: 494 LGRVGR 511
LGR+GR
Sbjct: 164 LGRIGR 169
>UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 320
Score = 70.1 bits (164), Expect = 3e-11
Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Frame = +2
Query: 98 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 277
EL + Y + + EE+L IP +D L V KE++D KLK+V G
Sbjct: 17 ELESKYEVTFPEGRDFTYEEVLEMIPEYDVLCSMFDFPVNKELIDHASKLKMVANYAVGY 76
Query: 278 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK---AGRWDRAL 448
+NIDV +KG+ V N P L LML +AR + L+ G L
Sbjct: 77 NNIDVAYCLEKGITVANTPDPVTAPTANLALGLMLDVARRITECDRKLRREGLGMKVGVL 136
Query: 449 YT-GSELAGKTLAILGLGRVGR 511
G + GKTL I+G+GR+G+
Sbjct: 137 ENLGINVTGKTLGIIGMGRIGK 158
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 70.1 bits (164), Expect = 3e-11
Identities = 39/120 (32%), Positives = 66/120 (55%), Gaps = 3/120 (2%)
Frame = +2
Query: 158 LLME-IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 334
LL E + + + LV +V E+L +L+V+ +A G DN+D+ + ++G+ N P
Sbjct: 39 LLYEWLADAEGLVSTGDVRVDDELLAHAPRLRVIAQASVGYDNVDIAACTRRGIPFGNTP 98
Query: 335 GANALSACELTCTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVG 508
G + +LT L+L AR + + +GRW + + G +L GKTL I+G+GR+G
Sbjct: 99 GVLVEATADLTFGLLLCAARRIHEGWNQVASGRWLNNHDVPFGIDLYGKTLGIVGMGRIG 158
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 70.1 bits (164), Expect = 3e-11
Identities = 36/131 (27%), Positives = 66/131 (50%), Gaps = 5/131 (3%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
K I ++EL+ + D ++ ++ E++++ LK V GVD++DV + +G
Sbjct: 30 KGSIPRDELMARVEGVDGIICLLTERIDGELINSSKNLKAVSCVSVGVDHVDVGTLTARG 89
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-----LYTGSELAGKT 478
+ + + PG + +L L+L AR + ++ G W A + G +AGKT
Sbjct: 90 IPLGHTPGVLVDATADLAFGLLLAAARRIPQGDRHVRTGGWQGASWSPKAFLGCSVAGKT 149
Query: 479 LAILGLGRVGR 511
L I+GLG +G+
Sbjct: 150 LGIIGLGDIGQ 160
>UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2;
Entamoeba histolytica|Rep: D-phosphoglycerate
dehydrogenase - Entamoeba histolytica
Length = 299
Score = 70.1 bits (164), Expect = 3e-11
Identities = 43/121 (35%), Positives = 67/121 (55%)
Frame = +2
Query: 149 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 328
KE+++ I + D ++VRS ++ +E++ AG K+K++ RAGAG DNID+++ + + V+N
Sbjct: 39 KEDVIERIKDADGVIVRS-DKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMN 97
Query: 329 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
PG N EL +M+ R K G+ G EL KTL I G G VG
Sbjct: 98 TPGQNRNGVAELCIGMMIFGFR------KGFKEGK-------GRELKDKTLGICGCGYVG 144
Query: 509 R 511
+
Sbjct: 145 K 145
>UniRef50_Q4PP80 Cluster: Putative glyoxylate
reductase/hydroxypyruvate reductase; n=1; Lysiphlebus
testaceipes|Rep: Putative glyoxylate
reductase/hydroxypyruvate reductase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 325
Score = 70.1 bits (164), Expect = 3e-11
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%)
Frame = +2
Query: 101 LLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAG 274
L N Y + K I + E L + + D + ++ +E+L AG KLKVV G
Sbjct: 21 LKNKYDLICWNKTTPIPRTEFLSMVKDVDGIFCLLTDKIDEEILSTAGSKLKVVSTMSVG 80
Query: 275 VDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRA 445
+D++++++ +G+ V PG + ELT L+L +R ++ A AL+ G W
Sbjct: 81 LDHLNLNALKTRGIHVGYTPGVLTDATAELTIGLLLATSRKIIAAEHALRNGEWTSWSPN 140
Query: 446 LYTGSELAGKTLAILGLGRVG 508
G LA T+ I+GLGR+G
Sbjct: 141 WMCGPGLANSTVGIVGLGRIG 161
>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1388 - Pyrococcus horikoshii
Length = 119
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/89 (47%), Positives = 49/89 (55%)
Frame = -1
Query: 477 VLPASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPA 298
VLP+SS+P+ +H P+ + A + A NIN SS L LA GAL T PF A
Sbjct: 5 VLPSSSIPIASFFAHTPSLIFLSAKAIFLATENINPTASSATLLELAAGALTTSIPFSLA 64
Query: 297 ESTSMLSTPAPARPTTFSFTPASNTSLVT 211
STSMLS P PA T SF S T LVT
Sbjct: 65 ASTSMLSKPTPALAITLSFGALSITLLVT 93
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 70.1 bits (164), Expect = 3e-11
Identities = 41/122 (33%), Positives = 64/122 (52%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+S EE L I D VV S ++ D+ LK+V G D++D+D+A KGV V
Sbjct: 34 LSMEEYLCRIAEADVAVV-SHFKLPARSFDSST-LKLVALTRTGYDDVDLDAATLKGVAV 91
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
NAPG + + E ++L R + A ++ ++D + G EL GKT+ I+G G+
Sbjct: 92 ANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEGRELRGKTMGIIGTGQ 151
Query: 503 VG 508
+G
Sbjct: 152 IG 153
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 69.7 bits (163), Expect = 4e-11
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 3/140 (2%)
Frame = +2
Query: 98 ELLNAYG---IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAG 268
E+LN G + K K++ E+ D ++ + T+ ++ LK++ R G
Sbjct: 22 EILNQSGWEIVTNPLKRKLTPLEVSEFAKEVDGII--AGTEDLTPLIHKNRNLKIISRVG 79
Query: 269 AGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL 448
G+D++ ++ ++G+ V P A ++ ELT LM+ R V A LK G W R
Sbjct: 80 IGLDSVPLNLCKERGIAVAYTPDAVTMAVAELTIGLMISSTRKVFLAHQELKTGGWSR-- 137
Query: 449 YTGSELAGKTLAILGLGRVG 508
+TG L T+ I+G+GRVG
Sbjct: 138 FTGKRLGESTIGIVGVGRVG 157
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 69.7 bits (163), Expect = 4e-11
Identities = 44/134 (32%), Positives = 72/134 (53%), Gaps = 4/134 (2%)
Frame = +2
Query: 122 ATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNID 289
AT + A++S + + HDA+ V EV+DA GVKL ++ R AG DN+D
Sbjct: 61 ATYSSARLSLDTASLA-QGHDAVCVFVDDDARGEVVDALAERGVKL-ILLRC-AGFDNVD 117
Query: 290 VDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELA 469
+ A ++G+ V+ P + LS E +M+ L RH+ + L+ G + GS +
Sbjct: 118 CERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVGSSMR 177
Query: 470 GKTLAILGLGRVGR 511
GKT+ ++G G++GR
Sbjct: 178 GKTVGVVGTGKIGR 191
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 69.3 bits (162), Expect = 5e-11
Identities = 48/165 (29%), Positives = 81/165 (49%), Gaps = 6/165 (3%)
Frame = +2
Query: 32 KPRMVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQ 211
KP +V+ K + D V + EL +A ++S+ E++ + D LV
Sbjct: 32 KPMVVLTRK---LPDPVETRMRELFDAR--LNIDDHRMSQPEIIAALKEADVLVPCITDV 86
Query: 212 VTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 388
+ V++ AG LK++ G GVDNIDV +A ++G+ V N P ++T L+L +
Sbjct: 87 IDAAVIEQAGPNLKLIANFGNGVDNIDVAAAARRGITVTNTPNVLTEDTADMTLALLLSV 146
Query: 389 ARHVVPASTAL--KAGR---WDRALYTGSELAGKTLAILGLGRVG 508
R +V + + + G+ W G + GK L I+G+GR+G
Sbjct: 147 PRRLVEGANVINERHGQWPGWSPTWMLGRRIWGKRLGIVGMGRIG 191
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 69.3 bits (162), Expect = 5e-11
Identities = 37/109 (33%), Positives = 59/109 (54%)
Frame = +2
Query: 185 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 364
A++ +T +T + A L++V GAG +NI+ D+A +GV V +AP N+ +
Sbjct: 50 AVLTNGSTGLTGAEMAALPALELVASFGAGYENIERDAARMRGVRVCHAPDTNSQVVADH 109
Query: 365 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+ML +R + LKAG+WD + GKTL I+GLG +G+
Sbjct: 110 ALAMMLAWSRGIAMLDRGLKAGQWDALRAPRPGVRGKTLGIVGLGNIGQ 158
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 69.3 bits (162), Expect = 5e-11
Identities = 38/107 (35%), Positives = 63/107 (58%), Gaps = 5/107 (4%)
Frame = +2
Query: 206 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 385
T +T+++L KL++V + G G+D ID++ A ++GV V G+NA + E T L+L
Sbjct: 60 TAITEKLLQESPKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILA 119
Query: 386 LARHVVPASTALKAGRWDRALYTG-----SELAGKTLAILGLGRVGR 511
R + A +++ G+W +YT +L+GKT+ ILG G +GR
Sbjct: 120 ALRRLALADQSMREGKW---IYTELRPLCRKLSGKTVGILGFGNIGR 163
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 69.3 bits (162), Expect = 5e-11
Identities = 42/118 (35%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
Frame = +2
Query: 167 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 346
E+ +VVR A + L+ KL+ + R GAG+D I V +A + G+ V N P NA
Sbjct: 35 ELAEASFVVVRRA--IPAGALENAPKLRALVRHGAGLDFIPVQAASRLGIAVTNTPSVNA 92
Query: 347 LSACELTCTLMLVLARHVVPASTALKAGRWD--RALYTGS-ELAGKTLAILGLGRVGR 511
S E L++ LAR +V ++ W RA GS E+AGK L ++G G +G+
Sbjct: 93 KSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAAPGSCEIAGKALGLIGYGGIGQ 150
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 69.3 bits (162), Expect = 5e-11
Identities = 36/125 (28%), Positives = 64/125 (51%), Gaps = 3/125 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+ +E LL + ++ + + +E+ + LKVV G DNID+ +A +K V V
Sbjct: 61 VPREILLEKAGEASGILSMLSDPIDRELFEKSPNLKVVANLAVGFDNIDLKAANEKDVAV 120
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 493
N P + +LT LM+ AR ++ A ++ G+ W L G+++ KT+ I+G
Sbjct: 121 CNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSPLLMAGTDIHHKTVGIIG 180
Query: 494 LGRVG 508
+G +G
Sbjct: 181 MGSIG 185
>UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Rep:
Glyoxylate reductase - Roseiflexus sp. RS-1
Length = 340
Score = 69.3 bits (162), Expect = 5e-11
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+ +E LL + + D ++ +V E+L A +LKVV G DN+D+ + +GV +
Sbjct: 35 VPRETLLRAVADVDGILTLLTDRVDTELLAAAPRLKVVANMAVGYDNVDLPALTARGVLL 94
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILG 493
N P + +L L+L +R VV + AG W G ++ G TL I+G
Sbjct: 95 TNTPDVLTETTADLVWALILAASRRVVEGHRLIAAGGWTTWSPMFMVGQDVHGATLGIVG 154
Query: 494 LGRVG 508
GR+G
Sbjct: 155 AGRIG 159
>UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p -
Drosophila melanogaster (Fruit fly)
Length = 362
Score = 69.3 bits (162), Expect = 5e-11
Identities = 43/128 (33%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
+ + EL+ + DAL +V KEVLDA G +LK V G D+IDV+ K+G+
Sbjct: 74 VPRSELIRVVAGKDALYCALTDKVDKEVLDAAGPQLKCVATISVGYDHIDVEECRKRGIR 133
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAIL 490
V P + ELT L+L R + A+ + G W G L G + +L
Sbjct: 134 VGFTPDVLTDATAELTLALLLATNRRLFEANKQVYNGGWKSWAPMWMCGQGLKGSRVGLL 193
Query: 491 GLGRVGRE 514
G GR+G+E
Sbjct: 194 GFGRIGQE 201
>UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase;
n=1; Rhodococcus sp. RHA1|Rep: Probable phosphoglycerate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 163
Score = 68.9 bits (161), Expect = 6e-11
Identities = 42/119 (35%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
Frame = +2
Query: 158 LLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPG 337
L+ P+ DAL+V VT +VL A LKV+ R G GVD+IDV +A + GV V N P
Sbjct: 14 LIARCPHADALIVW-VQPVTADVLAALPHLKVISRLGTGVDSIDVPAANRHGVVVTNVPD 72
Query: 338 ANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS--ELAGKTLAILGLGRVG 508
AN+ T L L R + +++ G+W A G + +T ++G G++G
Sbjct: 73 ANSEEVATHTMGLALAAHRRLPSFDKSVRQGQWHSAPIHGEIRRPSEQTFGVIGYGKIG 131
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 68.9 bits (161), Expect = 6e-11
Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 2/125 (1%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGV--KLKVVGRAGAGVDNIDVDSAGKKGV 316
+S+ EL+ +P D ++ T V +AG +LK + G GVDN+D + + G+
Sbjct: 79 LSEAELIELVPQFDGWIIGD-DPATARVFEAGKAGRLKAAVKWGVGVDNVDFAACQRLGL 137
Query: 317 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 496
+ N PG ++ ++ LAR +KAG W ++ G LAGKT+A+ G
Sbjct: 138 PISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AGISLAGKTVALAGF 195
Query: 497 GRVGR 511
G +GR
Sbjct: 196 GDIGR 200
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 68.9 bits (161), Expect = 6e-11
Identities = 52/152 (34%), Positives = 77/152 (50%), Gaps = 26/152 (17%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
K K+S +L+ E+ + ++V S +VT V+ A +L+V+ A NID +A +G
Sbjct: 31 KPKLSAGQLI-ELAHDAEVLVTSYDEVTDAVMAACPRLQVIACTRANPVNIDTQAAQARG 89
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-------------------- 433
+ V+ PG NA +A ELT LML LARH+ + ALK G
Sbjct: 90 IRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQADNASAATQQGLRRDVV 149
Query: 434 WDRA------LYTGSELAGKTLAILGLGRVGR 511
WD + ++ GSEL KTL ++G G +GR
Sbjct: 150 WDVSPESPYEVFKGSELRNKTLGLVGYGNIGR 181
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/143 (31%), Positives = 74/143 (51%), Gaps = 5/143 (3%)
Frame = +2
Query: 98 ELLNAYGI---ATTTKAKISKE--ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 262
E+L A G T+ + KE ++ ++ +DA V+ A ++EVL LKV+ R
Sbjct: 18 EILQAAGFEVDTVPTEVDLRKEPHRVVEQVQGYDA-VLAGAEIYSREVLQQLPDLKVISR 76
Query: 263 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 442
G G D +D+ +A + + V PG N S E L++ +AR A+++G W+R
Sbjct: 77 YGVGFDAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWER 136
Query: 443 ALYTGSELAGKTLAILGLGRVGR 511
L + G T+ I+GLGR+G+
Sbjct: 137 EL--TPRVWGSTIGIVGLGRIGQ 157
>UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidiphilium cryptum
JF-5|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidiphilium cryptum (strain JF-5)
Length = 328
Score = 68.9 bits (161), Expect = 6e-11
Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Frame = +2
Query: 110 AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNID 289
A GI ++S E I DA+++R+ + EV+ +L++V R G G D++D
Sbjct: 21 AEGITLDVVDEVSLESYAKLIVRADAVLIRTQP-MPAEVIATAPQLRIVSRHGVGYDSVD 79
Query: 290 VDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSEL 466
V + + + + N+ S E ++L LAR + A +AG W R ++
Sbjct: 80 VPALNARRIPLSLVGDVNSRSVAEHALMMILALARRLPDYDRATRAGEWHRRDSREAGDI 139
Query: 467 AGKTLAILGLGRVGR 511
AGK+L ++G GR+GR
Sbjct: 140 AGKSLLVIGFGRIGR 154
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 68.9 bits (161), Expect = 6e-11
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +2
Query: 113 YGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDV 292
+G K EE L+E + + T +VL L+ VG G N+D+
Sbjct: 44 FGPVGNVKEASGTEEQLLESLSGVQIAATQMAPFTADVLAKSPDLRFVGVCRGGPVNVDL 103
Query: 293 DSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY----TGS 460
+A + GV V APG NA +A E L+L R + + LK+G W Y G
Sbjct: 104 QAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYENAGI 163
Query: 461 ELAGKTLAILGLGRVGR 511
EL G T+ ++G G +GR
Sbjct: 164 ELEGSTVGLVGYGAIGR 180
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 68.9 bits (161), Expect = 6e-11
Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 2/104 (1%)
Frame = +2
Query: 206 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 385
T ++ +++A L+++ G G D +DV++A + GV V N P E+T LML
Sbjct: 55 TGCSRGIIEALPDLEIISSFGVGYDAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLA 114
Query: 386 LARHVVPASTALKAGRWDR--ALYTGSELAGKTLAILGLGRVGR 511
LA V + ++ GRW+ A+ +EL G T+ I+GLGR+G+
Sbjct: 115 LAHRVPESHAYVRDGRWETEGAMPLTAELTGATVGIIGLGRIGK 158
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 68.9 bits (161), Expect = 6e-11
Identities = 34/102 (33%), Positives = 55/102 (53%)
Frame = +2
Query: 206 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 385
+++T EVL +L+++ G D+ID+D G+ V N P + E L+L
Sbjct: 52 SRLTAEVLAQFPRLRLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLA 111
Query: 386 LARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
++RH+V + + G + + G EL GKTL +LG GR+GR
Sbjct: 112 VSRHIVTGAERTRRGDFSQHGLRGFELRGKTLGVLGTGRIGR 153
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 68.5 bits (160), Expect = 8e-11
Identities = 49/149 (32%), Positives = 75/149 (50%)
Frame = +2
Query: 65 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 244
+ VDG+ C + +G K ++EEL + +A +VRS ++ +E +
Sbjct: 71 IAVDGIEKICKDNGLTFGKIEGYK---TQEELYSAAESAEACIVRS-DKLDEEFFNRAKN 126
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
LK+V RAGAGVD ID+D+A K V V N PG NA + E+ L++ + R+ A+
Sbjct: 127 LKIVVRAGAGVDTIDLDAASKHHVVVENTPGQNANAVAEMVFALLIAMKRNHFDAT---- 182
Query: 425 AGRWDRALYTGSELAGKTLAILGLGRVGR 511
+G E+ G TL + G G V R
Sbjct: 183 ---------SGREIRGSTLGLYGCGNVSR 202
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 68.5 bits (160), Expect = 8e-11
Identities = 43/125 (34%), Positives = 66/125 (52%), Gaps = 6/125 (4%)
Frame = +2
Query: 155 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 334
EL +E +V+ S ++ + L A KL+ + G +N+DV++AGK+G+ V N P
Sbjct: 40 ELRVERAKDADIVLTSKVKLDEATLAALPKLRYISMLATGYNNVDVEAAGKRGIPVANIP 99
Query: 335 GANALSACELTCTLMLVLARHVVPASTALKAGRW----DRALYTGS--ELAGKTLAILGL 496
+ S + T L+L LA HV +A+KA W D + + EL G TL I+G
Sbjct: 100 AYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHSFWKTPIVELDGLTLGIVGY 159
Query: 497 GRVGR 511
G +GR
Sbjct: 160 GTIGR 164
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 68.5 bits (160), Expect = 8e-11
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Frame = +2
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
L V +G+G D ID+D+ + GV V+N G NA S E+T LML + R + + +L+
Sbjct: 85 LLAVSSSGSGCDTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLR 144
Query: 425 AGRWD-RALYTGSELAGKTLAILGLGRVGR 511
A + R G EL G+TL ++G+G GR
Sbjct: 145 AHNCESREDLMGHELRGRTLGLVGVGHAGR 174
>UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 339
Score = 68.5 bits (160), Expect = 8e-11
Identities = 36/112 (32%), Positives = 60/112 (53%), Gaps = 1/112 (0%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
D +++R+ VT E++ A L+++ R G GVDN+ + + +G+ V N PG+NA + E
Sbjct: 59 DGILLRTG-DVTAEMVLAAPNLRIISRNGTGVDNVPLPTCLSRGIAVTNIPGSNAFAVAE 117
Query: 362 LTCTLMLVLARHVVPASTALKAG-RWDRALYTGSELAGKTLAILGLGRVGRE 514
L LML + R VV ++ G R L GK + ++G+G + E
Sbjct: 118 LAIALMLTVLRRVVEVDKRIRGGERVPSIEALAPGLGGKKVGLVGMGDIAYE 169
>UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Psychroflexus torquis ATCC 700755|Rep:
D-3-phosphoglycerate dehydrogenase - Psychroflexus
torquis ATCC 700755
Length = 326
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/169 (30%), Positives = 87/169 (51%), Gaps = 8/169 (4%)
Frame = +2
Query: 32 KPRMVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNH--DALVVRSA 205
KP + +K +L DG+ +LL G K K+++ +L I + D ++V+ +
Sbjct: 3 KPHKKMKMK-ILATDGLSGIGVQLLENAGHEVIIK-KVAQNQLSEYITTNEFDGVLVKRS 60
Query: 206 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 385
T +TK +L LK +G +ID+D A +KG+ V A A++ S ELT +L
Sbjct: 61 TPLTKVILSESPTLKFIGNCDIISTHIDIDFAEQKGLSVFQAITASSNSIAELTIGHLLS 120
Query: 386 LARHVVPASTALKA---GRWD--RALYT-GSELAGKTLAILGLGRVGRE 514
RH+ ++ + ++D R Y+ G+E+ GK L I+G G VG+E
Sbjct: 121 CVRHLKDSNREMPLEGDSKFDTLRHSYSAGTEVEGKILGIIGFGNVGQE 169
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/122 (34%), Positives = 67/122 (54%), Gaps = 1/122 (0%)
Frame = +2
Query: 152 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 331
+E+L I + L+ +V +L KLK+V + GAG DN+D+D+ + G+ NA
Sbjct: 40 KEMLHHIEDCQVLIPEHI-KVDCSLLSIAKKLKLV-QTGAGFDNVDIDACTQYGIWAANA 97
Query: 332 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YTGSELAGKTLAILGLGRVG 508
G NA + E L+L +++ + +K + L YTGSEL GKT+ I+G G VG
Sbjct: 98 AGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYTGSELKGKTIGIIGFGAVG 157
Query: 509 RE 514
++
Sbjct: 158 KK 159
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 68.1 bits (159), Expect = 1e-10
Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +2
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
G KLK + + G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR
Sbjct: 96 GGKLKYISKQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDR 155
Query: 416 ALKAGRWDRAL--YTGSELAGKTLAILGLGRVG 508
++ G L + G L GKTL ++G G +G
Sbjct: 156 KIRKGASVTKLDGWKGQMLYGKTLGVIGGGNIG 188
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 68.1 bits (159), Expect = 1e-10
Identities = 37/110 (33%), Positives = 62/110 (56%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
+ L+V + T V ++L +L+ V A G DN+D+++ K G+ V N P A+A S E
Sbjct: 41 EILIVTTFTPVNGDLLKKMPRLRFVQVASIGYDNVDMNAMKKNGIMVSNIPTASADSVAE 100
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 511
+++L L + +++GRW R + S+L GKT I+G+G +GR
Sbjct: 101 HALSMVLSLIKDQRFLDAEIRSGRWPR-ITRSSDLMGKTFGIVGMGSIGR 149
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 68.1 bits (159), Expect = 1e-10
Identities = 41/123 (33%), Positives = 62/123 (50%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+S +E + I + D +VV V+ E L + +LK++ G DN+D++ A GV V
Sbjct: 33 VSLDEFIDRIKDADIVVV-GRYGVSAEALRSAPRLKMISLWQTGFDNVDLEEATDHGVIV 91
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
N P S E L L L R V A L+ G +D Y G++L KT+ +LG G
Sbjct: 92 SNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVGNQLMSKTIGVLGTGE 151
Query: 503 VGR 511
+G+
Sbjct: 152 IGK 154
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/140 (29%), Positives = 77/140 (55%), Gaps = 4/140 (2%)
Frame = +2
Query: 98 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 277
E+L++ + ++EE++ + DA++ + A ++ EV+ K K++ R G GV
Sbjct: 21 EVLSSLNVEFVATQCRTEEEVISACRDADAIINQYAP-ISAEVIAQLEKCKIISRYGVGV 79
Query: 278 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 445
+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+ +
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139
Query: 446 LYTGSELAGKTLAILGLGRV 505
+Y L G+TL ++GLGR+
Sbjct: 140 IY---RLRGRTLGLVGLGRI 156
>UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3;
Gammaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pseudomonas fluorescens
(strain PfO-1)
Length = 322
Score = 67.7 bits (158), Expect = 1e-10
Identities = 37/109 (33%), Positives = 57/109 (52%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DA++ R + E + A LK++ GAG + +D+ +A +G+ V N G NA S +
Sbjct: 47 DAVLTRGPLGLYAEEIAALPALKIICVIGAGYEQVDLQAASDRGLTVTNGAGVNASSVAD 106
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
++L L R + A++ G W + + LAGK L ILGLG VG
Sbjct: 107 HAMAMLLALVRDIPRCDGAVRRGEWPKIM--RPSLAGKRLGILGLGAVG 153
>UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 388
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/126 (31%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
Frame = +2
Query: 137 AKISKEELLMEIPNHDALVV-RSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
A+ + L + DALV+ R T++ + +L +LK++ + G ++D+D+ ++G
Sbjct: 98 AESDPQRLAERFASADALVLTRERTRIDEALLARLPRLKLISQTGKIAAHLDLDACTRRG 157
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILG 493
V V G + ++ EL TL+L R ++PA A + GRW + G LAG TL I G
Sbjct: 158 VAVAEGRG-SPIAPAELAWTLILNARRRLLPAIAAFREGRWQTNI--GERLAGLTLGIWG 214
Query: 494 LGRVGR 511
G++G+
Sbjct: 215 YGKIGQ 220
>UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2;
Alphaproteobacteria|Rep: Glycolate reductase - alpha
proteobacterium HTCC2255
Length = 319
Score = 67.7 bits (158), Expect = 1e-10
Identities = 37/126 (29%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Frame = +2
Query: 146 SKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
+KEE++ DA+V + + +V+ G +LK++ GVD+ D+ + +K + V
Sbjct: 36 TKEEIISASFEFDAIVPCHSEVFSSDVVSKFGPRLKIIANHSVGVDHCDLAALNEKNILV 95
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILG 493
N P + + E+ LML ARH V +++G W + G +L G + I+G
Sbjct: 96 TNTPDVLSDATAEIAMLLMLGAARHAVLGDEIVRSGNWKNWSPSFMVGKQLTGARIGIIG 155
Query: 494 LGRVGR 511
+GRVG+
Sbjct: 156 MGRVGQ 161
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 67.3 bits (157), Expect = 2e-10
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Frame = +2
Query: 125 TTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAG 304
T + +E L E+ D + + E + +LKVV G DNID+ A
Sbjct: 27 TEENIPMPRELFLKELEEADGVFTNLTDRFDVEAFERAKRLKVVSTMAVGYDNIDIKEAT 86
Query: 305 KKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGK 475
K+GV V + PG + +LT L++ R + + ++ +W + TG + G
Sbjct: 87 KRGVSVGHTPGVLTEATADLTFALLMATGRRLRESIDYVRNDQWKSWGPFMLTGQAIYGT 146
Query: 476 TLAILGLGRVGR 511
TL I+G+GR+G+
Sbjct: 147 TLGIIGMGRIGQ 158
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/116 (35%), Positives = 63/116 (54%), Gaps = 6/116 (5%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
D LVV S + V V + G L+VV N+D+ A G+ V++ P NA + E
Sbjct: 56 DVLVVESDS-VGGPVFERG--LRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAE 112
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDR------ALYTGSELAGKTLAILGLGRVGR 511
+T L+L +ARH++PA +++G R + G+E+AG T ++GLG VGR
Sbjct: 113 MTVALLLAVARHLIPADADVRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGR 168
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 9/118 (7%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
+ +V+RS T+V E L L + RAG GV+ I+V+ A + G V+N PG NA + E
Sbjct: 32 EGIVIRS-TKVKDEWLTPD--LLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKE 88
Query: 362 LTCTLMLVLARHVVPAS---------TALKAGRWDRALYTGSELAGKTLAILGLGRVG 508
L +L+ +R ++ AS L+ R+ Y G EL GKT+ +LGLG +G
Sbjct: 89 LVLCCLLLSSRPIIEASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIG 146
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/123 (30%), Positives = 67/123 (54%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 322
++ E++ + + VV A ++T+ V +A L V+ R G G + +DV++A G V
Sbjct: 44 LNVEDIRLLLEGAGGWVVGHA-RITRAVFEALPDLAVISRRGVGYEKVDVEAARDLGRVV 102
Query: 323 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 502
A G N S + +M+ + R A +A+KAG+W+ + G+EL + + I+G GR
Sbjct: 103 AIAAGGNDASVADQVIGMMISIGRRFQEAQSAMKAGKWN--ILVGTELYRRKVGIVGFGR 160
Query: 503 VGR 511
+GR
Sbjct: 161 IGR 163
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 67.3 bits (157), Expect = 2e-10
Identities = 44/137 (32%), Positives = 72/137 (52%), Gaps = 7/137 (5%)
Frame = +2
Query: 119 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRA----GAGVDNI 286
I T K +S E+++ I + V+ T+ E L + + + GRA G +N+
Sbjct: 42 ICTQKKTILSVEDIIALIGDKCDGVIGQLTEDWGETLFSALS-RAGGRAFSNMAVGYNNV 100
Query: 287 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---RALYTG 457
DV++A K GV V N PG + EL +L + AR +V A ++AG +D L+ G
Sbjct: 101 DVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVG 160
Query: 458 SELAGKTLAILGLGRVG 508
+ L G+T+ ++G GR+G
Sbjct: 161 NLLRGQTVGVIGAGRIG 177
>UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Vibrio|Rep: D-3-phosphoglycerate dehydrogenase - Vibrio
alginolyticus 12G01
Length = 166
Score = 66.9 bits (156), Expect = 3e-10
Identities = 35/115 (30%), Positives = 65/115 (56%), Gaps = 2/115 (1%)
Frame = +2
Query: 62 VLIVDGVGAKCAELLNAYGIATTT--KAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
+L+++G+ E+L A G K + +EEL+ + + + +RS T +++EV++A
Sbjct: 13 ILLLEGLHPSSVEVLQAAGYTNIEYHKGSLPEEELIEAVKDVHFIGIRSRTNLSEEVINA 72
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 400
KL +G G + +++D+A K+G+ V NAP +N S EL +L+L R +
Sbjct: 73 ANKLVAIGCFCIGTNQVNLDAAAKRGIPVFNAPFSNTRSVAELVLGQILLLVRGI 127
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 66.9 bits (156), Expect = 3e-10
Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 1/128 (0%)
Frame = +2
Query: 134 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 313
+A K+E ++++ +V + L LK++ R G G DN+D AG+ G
Sbjct: 26 EAPDDKQETILKVGKDADGIVLMTDPFDNQTLTKFTNLKIIARHGVGFDNVDEKFAGEHG 85
Query: 314 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YTGSELAGKTLAIL 490
V V P ANA + E T +L L++++ S ++ G + L + G +L+ K + ++
Sbjct: 86 VYVTITPMANASTVAETTIAEILDLSKNLTKISDEMRQGNFAYKLDHMGFDLSHKKIGVM 145
Query: 491 GLGRVGRE 514
G GR+GR+
Sbjct: 146 GYGRIGRQ 153
>UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: D-3-phosphoglycerate
dehydrogenase - Microscilla marina ATCC 23134
Length = 322
Score = 66.9 bits (156), Expect = 3e-10
Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 6/160 (3%)
Frame = +2
Query: 50 DIKSVLIVDGVGAKCAELLNAYGIATTTK-AKISKEELLMEIPNHD-ALVVRSATQVTKE 223
+I VL +DG L+ Y T+ + S E + I H +V A + +E
Sbjct: 3 EIPIVLKIDGATYFEMPQLDGYLAKHQTRLVEASLNEAISAINEHSPGAIVSGAAPIGRE 62
Query: 224 VLDAGVK--LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 397
++DAG++ L+ + +AG G+DNID + A + + V N P + E LML LAR
Sbjct: 63 IMDAGLQKGLRGIVKAGTGLDNIDCEYARCQQILVENIPDYVHETVAEYAINLMLSLARK 122
Query: 398 VVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGR 511
P ++ W G+EL GKT+ ++G GR+ R
Sbjct: 123 SWPVQQTMRQKGWFDITPASLGTELNGKTIGLVGFGRIAR 162
>UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 323
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/126 (30%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 319
I + ELL + A+ ++ EVLDA G +LKVV G D+++ K+G+
Sbjct: 35 IPRNELLNRVKGKHAIFCLLTEKIDAEVLDACGPQLKVVATMSVGYDHVNTKEIEKRGLQ 94
Query: 320 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY-TGSELAGKTLAIL 490
+ PG + L L+L ++R +V A+ K G W + ++ TG+ L G T+ ++
Sbjct: 95 LGFTPGVLTDATATLNVALLLAVSRRIVEAAAEAKNGGWGTWKPMWMTGATLKGSTVGVV 154
Query: 491 GLGRVG 508
G GR+G
Sbjct: 155 GFGRIG 160
>UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Caldivirga
maquilingensis IC-167|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Caldivirga
maquilingensis IC-167
Length = 326
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DALVV +V VL + K+KV+ G D+ID+D+A ++G+ V P + +
Sbjct: 53 DALVVTIGDRVDDYVL-SNAKVKVIATYSVGYDHIDLDAATRRGIPVGYTPEVLVEAVAD 111
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRAL--YTGSELAGKTLAILGLGRVG 508
L L++ LAR V+ +++G + + G+E+ GKTL ILGLG +G
Sbjct: 112 LAIGLIITLARRVIEGDRLVRSGEAYKVWGEFLGTEVWGKTLGILGLGNIG 162
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/130 (33%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
Frame = +2
Query: 122 ATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSA 301
A AK + L P H V AT + L+A +KVV R G G D +DV +
Sbjct: 34 ANLISAKDFQALLKSHAPVHG--VALGATAFGETELEASKDMKVVTRIGVGYDAVDVPAL 91
Query: 302 GKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKT 478
++ V ++ A AN+ S E +ML LA+ + +K G+W DR +L GKT
Sbjct: 92 SRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSCVKDGKWADRLGMLPFDLYGKT 151
Query: 479 LAILGLGRVG 508
+ I+G GR+G
Sbjct: 152 VLIIGFGRIG 161
>UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 309
Score = 66.5 bits (155), Expect = 3e-10
Identities = 32/114 (28%), Positives = 61/114 (53%), Gaps = 1/114 (0%)
Frame = +2
Query: 176 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 355
N +A+++RS T++ + ++ +++V G G DN+ + + N PG +
Sbjct: 41 NFEAILIRSNTKLPQSLIQQIPSIRLVATCGVGYDNLPLPYLKANNIKASNTPGVLNDAV 100
Query: 356 CELTCTLMLVLARHVVPASTALKAGRWDRALY-TGSELAGKTLAILGLGRVGRE 514
CEL +ML L R + + +K+ W +A + + LAGK + I G+GR+G++
Sbjct: 101 CELAIGMMLSLMRRIPESQEYVKSSAWSKAPFKLTTTLAGKRVGIAGMGRIGQD 154
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 66.5 bits (155), Expect = 3e-10
Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Frame = +2
Query: 191 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 370
V+ A +T+E+LD KL + G G D+ID++ +KGV ++N PG N+ ELT
Sbjct: 83 VICRANLITREMLDKEGKLMGLAIVGVGYDSIDIEGCKEKGVTLMNCPGENSQVVAELTL 142
Query: 371 TLMLVLARHVVPASTALKAGRWDRALYT-GSELAGKTLAILGLGRVGR 511
+L L L R V L+AG ++ G L GK + ++G+ R
Sbjct: 143 SLTLALLRRVPELDRRLRAGETMLSINNLGRTLRGKVVGMVGISATAR 190
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 66.1 bits (154), Expect = 4e-10
Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 3/113 (2%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
+AL+V + +T+ LD L+V+G G++++ + S +G+ ++N G + +
Sbjct: 61 EALIVLLSEPLTEADLDLCPNLRVIGTYSVGINHLPITSCQSRGIRIVNTQGVLTDATAD 120
Query: 362 LTCTLMLVLARHVVPASTALKAGRWD---RALYTGSELAGKTLAILGLGRVGR 511
L TL+L L R V +++G W L G+ L GKT ILG G +GR
Sbjct: 121 LALTLLLSLTRRVREGEALVRSGHWKGWAPDLLLGTGLTGKTCGILGSGPIGR 173
>UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=8; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 335
Score = 66.1 bits (154), Expect = 4e-10
Identities = 32/110 (29%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +2
Query: 191 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 370
++ S+ +T +L + +LKV+ GVDN D+ + +G+ + + PG + +
Sbjct: 57 MIGSSYAITASLLASAPQLKVISSVSVGVDNYDLPALAARGIMLCHTPGVLTETTADTIF 116
Query: 371 TLMLVLARHVVPASTALKAGRWDRAL---YTGSELAGKTLAILGLGRVGR 511
+L++ +R +V ++ ++ GRW R + G ++ GKTL ILG GR+G+
Sbjct: 117 SLIMASSRRLVELASHVREGRWTRNIGEDLFGWDVHGKTLGILGFGRIGQ 166
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/125 (29%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVL-DAGVKLKVVGRAGAGVDN-IDVDSAGKKGV 316
+ ++E++ + DA + VT++++ A LKV+ G G +DV +A K +
Sbjct: 44 LKEDEIIEALAGVDAYIPGGEEVVTEKIIASAKNTLKVISFNGVGYGYYVDVPAAKKHNI 103
Query: 317 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 496
V N P AN+L+ E T L+L L + + + K+G W + Y +++ KT+ I+G+
Sbjct: 104 AVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQDVSDKTIGIVGM 161
Query: 497 GRVGR 511
G +GR
Sbjct: 162 GSIGR 166
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 65.7 bits (153), Expect = 6e-10
Identities = 36/109 (33%), Positives = 57/109 (52%), Gaps = 1/109 (0%)
Frame = +2
Query: 188 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 367
L+VRS+ ++++ L +G+ G G+D IDVD+ +G+ + N PG NA + EL
Sbjct: 61 LLVRSSRLTAQDIISCP-NLVAIGKQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELV 119
Query: 368 CTLMLVLARHVVPASTALKAG-RWDRALYTGSELAGKTLAILGLGRVGR 511
TL AR V +G + +G L KT+ ILG+G +G+
Sbjct: 120 LTLATASARQVGSIIAKQSSGILVPKEKCSGLILHEKTIGILGMGNIGK 168
>UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3;
Cyanobacteria|Rep: Glycerate dehydrogenase - Anabaena
sp. (strain PCC 7120)
Length = 332
Score = 65.7 bits (153), Expect = 6e-10
Identities = 43/154 (27%), Positives = 77/154 (50%), Gaps = 4/154 (2%)
Frame = +2
Query: 62 VLIVDGVGAKCAELL--NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 235
V+I + V + ELL + IA +K +S+EE+L + +AL+V + + L
Sbjct: 5 VVITNWVHPEVIELLKPSCEVIANPSKEALSREEILQRAKDAEALMVFMPDTIDEAFLRE 64
Query: 236 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 415
KLK++ A G DN DV + +G+ P + E+T L++ L R ++
Sbjct: 65 CPKLKIIAAALKGYDNFDVAACTHRGIWFTIVPSLLSAPTAEITIGLLIGLGRQMLEGDR 124
Query: 416 ALKAGRWD--RALYTGSELAGKTLAILGLGRVGR 511
++ G++ R + LA +TL I+G+G +G+
Sbjct: 125 FIRTGKFTGWRPQFYSLGLANRTLGIVGMGALGK 158
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 65.7 bits (153), Expect = 6e-10
Identities = 38/98 (38%), Positives = 55/98 (56%), Gaps = 10/98 (10%)
Frame = +2
Query: 245 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 424
+K V RAGAGV+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 50 VKAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVK 109
Query: 425 ----------AGRWDRALYTGSELAGKTLAILGLGRVG 508
+ + G+ELAGK L I+GLG +G
Sbjct: 110 ELPAEDDVEQKVEAGKKAFAGTELAGKKLGIIGLGAIG 147
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 65.7 bits (153), Expect = 6e-10
Identities = 38/125 (30%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = +2
Query: 143 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK--LKVVGRAGAGVDNIDVDSAGKKGV 316
+S EL+ +P D ++ T+ V AGV+ LK + G GVDN+D +A G+
Sbjct: 37 LSVAELVDLLPGFDGWIIGD-DPATRAVFAAGVRGRLKAAVKWGVGVDNVDFAAARALGI 95
Query: 317 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 496
+ N P ++ + + LAR ++AG W + G LAGKT+A++G
Sbjct: 96 PIANTPAMFGAEVADVAVSYVTALARETFSVDREVRAGGWPKP--CGVSLAGKTVALVGF 153
Query: 497 GRVGR 511
G +G+
Sbjct: 154 GDIGK 158
>UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Actinomycetales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 326
Score = 65.7 bits (153), Expect = 6e-10
Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Frame = +2
Query: 182 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 361
DALVV+ A +V ++LDA ++ VGR G GVD +DVD+ +GV V N P S +
Sbjct: 46 DALVVQYA-RVDADLLDALPTVRAVGRYGVGVDTVDVDACTARGVAVCNVPDYGTESVSD 104
Query: 362 LTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVG 508
L L AR + ++AG + A L + G+ ++GLG +G
Sbjct: 105 HAIALALAAARRIAWMDRRVRAGAGELAPLRPVHQFGGRVFGVVGLGLIG 154
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 538,029,943
Number of Sequences: 1657284
Number of extensions: 11108914
Number of successful extensions: 65609
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 56135
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 64656
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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