Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= epV31563
(516 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P55072 Cluster: Transitional endoplasmic reticulum ATPa... 225 4e-58
UniRef50_A4ICJ9 Cluster: Transitional endoplasmic reticulum ATPa... 163 2e-39
UniRef50_Q4Y788 Cluster: Cell division cycle protein 48 homologu... 151 9e-36
UniRef50_UPI0000E4A84B Cluster: PREDICTED: similar to valosin; n... 135 6e-31
UniRef50_A0EEE7 Cluster: Chromosome undetermined scaffold_91, wh... 105 8e-22
UniRef50_Q4YQQ6 Cluster: Cell division cycle ATPase, putative; n... 68 1e-10
UniRef50_A5KAB5 Cluster: Cell division cycle ATPase, putative; n... 64 2e-09
UniRef50_Q7QWL6 Cluster: GLP_762_31096_33708; n=1; Giardia lambl... 61 1e-08
UniRef50_A7AVE1 Cluster: Cell division cycle protein ATPase, put... 50 2e-05
UniRef50_Q4MZM6 Cluster: Cell division cycle protein 48, putativ... 49 7e-05
UniRef50_Q1JSD1 Cluster: Transitional endoplasmic reticulum ATPa... 49 7e-05
UniRef50_Q4UBT9 Cluster: Cell divison cycle CDC48 homologue, put... 47 3e-04
UniRef50_A2FWK7 Cluster: ATPase, AAA family protein; n=1; Tricho... 35 0.96
UniRef50_UPI0000499E59 Cluster: hypothetical protein 73.t00008; ... 33 2.9
UniRef50_Q7QTA1 Cluster: GLP_15_26945_31573; n=3; root|Rep: GLP_... 33 2.9
UniRef50_Q28VJ3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.1
UniRef50_Q4E0K4 Cluster: Ubiquitin hydrolase, putative; n=3; Try... 32 8.9
UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1; ... 32 8.9
>UniRef50_P55072 Cluster: Transitional endoplasmic reticulum ATPase
(TER ATPase) (15S Mg(2+)- ATPase p97 subunit); n=169;
Eukaryota|Rep: Transitional endoplasmic reticulum ATPase
(TER ATPase) (15S Mg(2+)- ATPase p97 subunit) - Homo
sapiens (Human)
Length = 806
Score = 225 bits (551), Expect = 4e-58
Identities = 104/147 (70%), Positives = 124/147 (84%)
Frame = +2
Query: 74 ADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKR 253
AD+K DDLSTAIL++K+RPNRLIV+EA+++DNSVV+LSQ KM++LQLFRGDTVLLKGK+
Sbjct: 5 ADSKG-DDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKK 63
Query: 254 RKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSV 433
R+E VCIVLSDD C DEKIRM DV+SI PCP VKYGKR+H+LPIDD+V
Sbjct: 64 RREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTV 123
Query: 434 EGLTGNLFEVYLKPYFMEAYRPIHRDD 514
EG+TGNLFEVYLKPYF+EAYRPI + D
Sbjct: 124 EGITGNLFEVYLKPYFLEAYRPIRKGD 150
>UniRef50_A4ICJ9 Cluster: Transitional endoplasmic reticulum ATPase,
putative; n=2; Leishmania|Rep: Transitional endoplasmic
reticulum ATPase, putative - Leishmania infantum
Length = 690
Score = 163 bits (396), Expect = 2e-39
Identities = 72/131 (54%), Positives = 94/131 (71%)
Frame = +2
Query: 122 KDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPD 301
K + N+LIVEE +DDNSVV+L+ +ME+L +FRGDTVL+KGK+ + TVCI + DD CP
Sbjct: 11 KVKLNKLIVEEPYNDDNSVVSLNPKRMEELNIFRGDTVLVKGKKHRSTVCIAMEDDECPP 70
Query: 302 EKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFEVYLKPYF 481
EKI+M D + I PC V YG RVH+LPIDD+VE LTG+LFE +LKPYF
Sbjct: 71 EKIKMNKVARRNIRIHLGDTIRIVPCKDVPYGNRVHLLPIDDTVENLTGDLFENFLKPYF 130
Query: 482 MEAYRPIHRDD 514
+E+YRP+ + D
Sbjct: 131 LESYRPVKKGD 141
>UniRef50_Q4Y788 Cluster: Cell division cycle protein 48 homologue,
putative; n=4; Plasmodium|Rep: Cell division cycle
protein 48 homologue, putative - Plasmodium chabaudi
Length = 250
Score = 151 bits (366), Expect = 9e-36
Identities = 69/147 (46%), Positives = 99/147 (67%), Gaps = 1/147 (0%)
Frame = +2
Query: 77 DNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRR 256
D K+ D + L +K RLIVEEA +DDNSVVAL+ +ME+L FRGDT+L+KGK+R
Sbjct: 6 DTKTLGDDNNGKLPKKKNLCRLIVEEATNDDNSVVALNTKRMEELNFFRGDTILIKGKKR 65
Query: 257 KETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVE 436
T+CI+L+D++ + KIR+ D+V + CP + YGK++ +LPIDD++E
Sbjct: 66 HSTICIILNDNDLDEGKIRINKVARKNLRVCLGDIVYVKACPEIPYGKKIQVLPIDDTIE 125
Query: 437 GLT-GNLFEVYLKPYFMEAYRPIHRDD 514
GL LFE++LKPYF E+YRP+ + D
Sbjct: 126 GLAKDTLFEIFLKPYFNESYRPVKKGD 152
>UniRef50_UPI0000E4A84B Cluster: PREDICTED: similar to valosin; n=3;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
valosin - Strongylocentrotus purpuratus
Length = 596
Score = 135 bits (326), Expect = 6e-31
Identities = 78/148 (52%), Positives = 100/148 (67%)
Frame = +2
Query: 71 MADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGK 250
MA+N S DD++TAILR K +PNRL+VEEA++DDNSVV+LSQAKM++LQLFRGDTV+LKGK
Sbjct: 1 MAEN-SGDDIATAILRTKAKPNRLVVEEAINDDNSVVSLSQAKMDELQLFRGDTVMLKGK 59
Query: 251 RRKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDS 430
+R++TVCIVLSDD D+KIR+ V+ RV + D
Sbjct: 60 KRRDTVCIVLSDDTVTDDKIRVNRV--------------------VRSNLRVR---LGDI 96
Query: 431 VEGLTGNLFEVYLKPYFMEAYRPIHRDD 514
V L F+VYL+PYF EAYRP+ + D
Sbjct: 97 VRNL----FDVYLRPYFQEAYRPVRKGD 120
>UniRef50_A0EEE7 Cluster: Chromosome undetermined scaffold_91, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_91,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 772
Score = 105 bits (251), Expect = 8e-22
Identities = 55/128 (42%), Positives = 77/128 (60%), Gaps = 1/128 (0%)
Frame = +2
Query: 134 NRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIR 313
NRL+V E+ +DDNSVV L Q K+ +L+LF+GD VLL+GK K+TV I +S+ E +
Sbjct: 17 NRLMVCESTADDNSVVQLCQDKLNELKLFKGDMVLLEGKNNKKTVAIAISNRQ-DKESVH 75
Query: 314 MXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLT-GNLFEVYLKPYFMEA 490
M D ++I P S+ +VHILP DS+ G NL + YL PYF++A
Sbjct: 76 MNSVIRKNLGIQIGDFITIQPTASLPQLTKVHILPFQDSISGTNEKNLTQNYLIPYFLDA 135
Query: 491 YRPIHRDD 514
YRP+ + D
Sbjct: 136 YRPVSKGD 143
>UniRef50_Q4YQQ6 Cluster: Cell division cycle ATPase, putative; n=3;
Plasmodium (Vinckeia)|Rep: Cell division cycle ATPase,
putative - Plasmodium berghei
Length = 932
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/130 (30%), Positives = 66/130 (50%), Gaps = 2/130 (1%)
Frame = +2
Query: 131 PNRLIVEEAVSD-DNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEK 307
PN +VE + DN + +S+ KM++L + G TVLLKGK++KE V IV D+
Sbjct: 101 PNYCLVENIDENADNFDIYMSKEKMKELNINDGFTVLLKGKKKKEMVAIVREDNRLNKYS 160
Query: 308 IRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFE-VYLKPYFM 484
+ + +D++ I P ++K K V + P +D+V +T E L Y
Sbjct: 161 VSISFSIKRNLRLMHNDIIKIYPLSNIKNIKNVILSPFNDTVNNITKQEIEKEILNTYLK 220
Query: 485 EAYRPIHRDD 514
+Y+P+ D+
Sbjct: 221 NSYKPLSVDN 230
>UniRef50_A5KAB5 Cluster: Cell division cycle ATPase, putative; n=1;
Plasmodium vivax|Rep: Cell division cycle ATPase,
putative - Plasmodium vivax
Length = 1089
Score = 64.1 bits (149), Expect = 2e-09
Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 2/126 (1%)
Frame = +2
Query: 131 PNRLIVEEAVSD-DNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEK 307
P+ +VE DN + LS+AKME+L L G TVLLKGK++KE + I D
Sbjct: 270 PSYCLVENVDEQIDNCEIYLSKAKMEELNLSEGFTVLLKGKKKKEMLAIAKLDRRLQKHF 329
Query: 308 IRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLT-GNLFEVYLKPYFM 484
+ + +D++ I P V + V + P D+V GL+ L + L+PY
Sbjct: 330 VVISFAMKKNLRLMHNDIIKIFPLMKVHPLRTVVLSPFSDTVGGLSKAELEQEVLRPYLK 389
Query: 485 EAYRPI 502
++P+
Sbjct: 390 GTFKPL 395
>UniRef50_Q7QWL6 Cluster: GLP_762_31096_33708; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_762_31096_33708 - Giardia lamblia
ATCC 50803
Length = 870
Score = 61.3 bits (142), Expect = 1e-08
Identities = 33/103 (32%), Positives = 52/103 (50%)
Frame = +2
Query: 134 NRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIR 313
NR IV + D+S + LS K+ L LF+GD V LKG+ K T +V S ++ +
Sbjct: 12 NRFIVNDNPGGDDSQIILSSEKVNVLDLFQGDYVRLKGRFGKTTHAMVQSREDVDKIVVL 71
Query: 314 MXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGL 442
M D+V + P ++ Y KR+ ++P + +EGL
Sbjct: 72 MNKTMRANLGVNLGDIVILYPAQNLPYHKRIKVIPFEQDLEGL 114
>UniRef50_A7AVE1 Cluster: Cell division cycle protein ATPase,
putative; n=1; Babesia bovis|Rep: Cell division cycle
protein ATPase, putative - Babesia bovis
Length = 922
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Frame = +2
Query: 131 PNRLIVEEAVSDDNSVVALSQAK--MEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDE 304
PN L V V D NS + + K +L + G+ V ++GK+R +TVC+V D N D
Sbjct: 133 PN-LFVLSGVFDGNSSIEIRMGKEPANKLGVAEGNLVRVRGKKRCDTVCVVGIDPNITDN 191
Query: 305 KIRMXXXXXXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSV 433
++ + DV+SI + K V ++P +DSV
Sbjct: 192 QVLIHSDTRRNLKLRTGDVMSIDLISDIPPAKLVKLMPFEDSV 234
>UniRef50_Q4MZM6 Cluster: Cell division cycle protein 48, putative;
n=1; Theileria parva|Rep: Cell division cycle protein
48, putative - Theileria parva
Length = 954
Score = 48.8 bits (111), Expect = 7e-05
Identities = 29/97 (29%), Positives = 46/97 (47%)
Frame = +2
Query: 164 DDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXX 343
+ N V + +A+ +L + GD + +KG+RRK TVC V ++ ++
Sbjct: 154 NSNVNVRIGKAQANKLSVMPGDLLKVKGRRRKVTVCGVDVTESITKNEVSFHEDLRRNLR 213
Query: 344 XXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNL 454
DVV + +V K VHILP D++E L L
Sbjct: 214 LRLGDVVFMEKINTVPEAKFVHILPFKDTIEPLIKQL 250
>UniRef50_Q1JSD1 Cluster: Transitional endoplasmic reticulum ATPase;
n=1; Toxoplasma gondii|Rep: Transitional endoplasmic
reticulum ATPase - Toxoplasma gondii
Length = 792
Score = 48.8 bits (111), Expect = 7e-05
Identities = 23/78 (29%), Positives = 39/78 (50%)
Frame = +2
Query: 200 MEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXXXXXSDVVSIAPC 379
M LQ+ RGD VLL G+R++ETV I + D + + + D + + P
Sbjct: 1 MAALQVQRGDVVLLSGRRKRETVAIAMPDRSLEARHVVLHAHALKNIKLHAQDAIKVTPQ 60
Query: 380 PSVKYGKRVHILPIDDSV 433
+ + +RV +LP D++
Sbjct: 61 RLLPHARRVFVLPFSDTL 78
>UniRef50_Q4UBT9 Cluster: Cell divison cycle CDC48 homologue,
putative or transitional endoplasmic reticulum ATPase,
putative; n=1; Theileria annulata|Rep: Cell divison
cycle CDC48 homologue, putative or transitional
endoplasmic reticulum ATPase, putative - Theileria
annulata
Length = 905
Score = 46.8 bits (106), Expect = 3e-04
Identities = 27/97 (27%), Positives = 45/97 (46%)
Frame = +2
Query: 164 DDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXXXXXXX 343
+ N V + + + +L L GD V ++G+RRK TVC V ++ ++
Sbjct: 129 NSNVNVKIGKEQANKLNLMTGDFVKVRGRRRKVTVCGVDVTESITKNEVSFHEDLRRNLR 188
Query: 344 XXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNL 454
D+V + ++ K VHILP D++E L L
Sbjct: 189 LRLGDIVFMDKINTIPEAKIVHILPFKDTIEPLIKQL 225
>UniRef50_A2FWK7 Cluster: ATPase, AAA family protein; n=1;
Trichomonas vaginalis G3|Rep: ATPase, AAA family protein
- Trichomonas vaginalis G3
Length = 2005
Score = 35.1 bits (77), Expect = 0.96
Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Frame = +2
Query: 152 EAVSDDNSVVA-LSQAKMEQLQLFRGDTVLLKGKRRKETVCIVLSDDNCPDEKIRMXXXX 328
+ V D N + A +S M L + G V ++ ++ +T+ + D PD IR+
Sbjct: 9 DKVDDFNDLNAYISNKAMNALGISDGSVVSVRNQQNSQTLVAIQGCD-MPDNVIRLSRCH 67
Query: 329 XXXXXXXXSDVVSIAPCPSVKYGKRVHILPIDDSVEGLTGNLFEV 463
+ V I+ + + V + PI D++ G++GN ++
Sbjct: 68 RINIGSFLGETVKISKPIKSQKAEIVLVAPIADTINGISGNFCDL 112
>UniRef50_UPI0000499E59 Cluster: hypothetical protein 73.t00008;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 73.t00008 - Entamoeba histolytica HM-1:IMSS
Length = 586
Score = 33.5 bits (73), Expect = 2.9
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Frame = +2
Query: 71 MADNKSPDDLSTAILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFR-----GDTV 235
++D+ S DD+ T + + + L ++ DD+ AL++ + E+ + F D
Sbjct: 130 ISDSDSDDDVKTDVKKTTTKKEELSDSDSDDDDDIAAALAKKRAERAKKFAISDSDSDDD 189
Query: 236 LLKGKRRKETVCIVLSDDNCPDEKIR 313
+K +K T I LSD + D+ I+
Sbjct: 190 DIKPAAKKTTKKISLSDSDSDDDDIK 215
>UniRef50_Q7QTA1 Cluster: GLP_15_26945_31573; n=3; root|Rep:
GLP_15_26945_31573 - Giardia lamblia ATCC 50803
Length = 1542
Score = 33.5 bits (73), Expect = 2.9
Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 8/87 (9%)
Frame = -2
Query: 437 PQLN-HQLAVCGLVFHISLKDTELWIPHQKDAHEGCFSRHGSSEFSH-------QGNYHL 282
P +N + +++ G + S K+ +P HEG FS E+ H G Y
Sbjct: 1125 PHMNPYTISISGTRYEFSTKNDTYTVPFPLTVHEGRFSVPTKIEYFHPDRPTCKDGEYAW 1184
Query: 281 RARCKRFPCGVCL*ARLCHHGRVEVAP 201
R + F C +C C G + P
Sbjct: 1185 RLQTGAFTCMICPTGYFCSEGVMNPCP 1211
>UniRef50_Q28VJ3 Cluster: Putative uncharacterized protein; n=1;
Jannaschia sp. CCS1|Rep: Putative uncharacterized
protein - Jannaschia sp. (strain CCS1)
Length = 348
Score = 32.7 bits (71), Expect = 5.1
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Frame = +2
Query: 86 SPDDLST--AILRRKDRPNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRK 259
S DL+T A++R + +P R+ + DD + + + ME L GD + L G++
Sbjct: 259 SAADLATGRAVVRDRTKPMRIFYH-LMLDDPACLLVENCPMETAHL--GDVMALGGRQIS 315
Query: 260 ETVCIVLSD 286
+ C VLSD
Sbjct: 316 QAACPVLSD 324
>UniRef50_Q4E0K4 Cluster: Ubiquitin hydrolase, putative; n=3;
Trypanosoma cruzi|Rep: Ubiquitin hydrolase, putative -
Trypanosoma cruzi
Length = 1135
Score = 31.9 bits (69), Expect = 8.9
Identities = 9/17 (52%), Positives = 13/17 (76%)
Frame = -2
Query: 230 CHHGRVEVAPFWPVKVP 180
CHH R +++PFW + VP
Sbjct: 752 CHHTRTQLSPFWDISVP 768
>UniRef50_A6R127 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 885
Score = 31.9 bits (69), Expect = 8.9
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +2
Query: 131 PNRLIVEEAVSDDNSVVALSQAKMEQLQLFRGDTVLLKGKRRKET 265
P R +A SD+ S+V + ++ + +++ RGDT L KGKR+ T
Sbjct: 407 PERCGDVDATSDERSMVVVEESYLP-VEIDRGDTRLGKGKRKAST 450
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 519,426,489
Number of Sequences: 1657284
Number of extensions: 9790822
Number of successful extensions: 24668
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 24029
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24662
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 31782822356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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